CN115501169A - Traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease - Google Patents
Traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease Download PDFInfo
- Publication number
- CN115501169A CN115501169A CN202211417558.0A CN202211417558A CN115501169A CN 115501169 A CN115501169 A CN 115501169A CN 202211417558 A CN202211417558 A CN 202211417558A CN 115501169 A CN115501169 A CN 115501169A
- Authority
- CN
- China
- Prior art keywords
- root
- raw materials
- disease
- crohn
- filtrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 48
- 208000011231 Crohn disease Diseases 0.000 title claims abstract description 37
- 206010000060 Abdominal distension Diseases 0.000 title claims abstract description 34
- 241000792859 Enema Species 0.000 title claims abstract description 18
- 239000007920 enema Substances 0.000 title claims abstract description 18
- 229940095399 enema Drugs 0.000 title claims abstract description 18
- 239000000706 filtrate Substances 0.000 claims abstract description 27
- 239000002994 raw material Substances 0.000 claims abstract description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 238000002156 mixing Methods 0.000 claims abstract description 17
- 229940079593 drug Drugs 0.000 claims abstract description 16
- 238000009835 boiling Methods 0.000 claims abstract description 13
- 238000001914 filtration Methods 0.000 claims abstract description 13
- 240000000691 Houttuynia cordata Species 0.000 claims abstract description 11
- 244000234609 Portulaca oleracea Species 0.000 claims abstract description 11
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 11
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 10
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 10
- 241000099774 Cuscuta salina Species 0.000 claims abstract description 9
- 235000013717 Houttuynia Nutrition 0.000 claims abstract description 9
- 240000004510 Agastache rugosa Species 0.000 claims abstract description 8
- 241000758794 Asarum Species 0.000 claims abstract description 8
- 241001071917 Lithospermum Species 0.000 claims abstract description 7
- 229940107666 astragalus root Drugs 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims abstract description 3
- 241000207929 Scutellaria Species 0.000 claims description 8
- 239000009636 Huang Qi Substances 0.000 claims description 5
- 241000130781 Arnebia Species 0.000 claims description 4
- 244000150195 Cyperus longus Species 0.000 claims description 4
- 235000018109 Cyperus longus Nutrition 0.000 claims description 4
- 244000075634 Cyperus rotundus Species 0.000 claims description 4
- 235000005010 Scirpus paludosus Nutrition 0.000 claims description 4
- 238000002791 soaking Methods 0.000 claims description 4
- 241001529821 Agastache Species 0.000 claims description 2
- 235000013719 Houttuynia cordata Nutrition 0.000 claims description 2
- 241001162994 Rugosus Species 0.000 claims description 2
- 240000004534 Scutellaria baicalensis Species 0.000 claims description 2
- 235000017089 Scutellaria baicalensis Nutrition 0.000 claims description 2
- 241001573366 Astragalus membranaceus Species 0.000 claims 1
- 241000037740 Coptis chinensis Species 0.000 claims 1
- 244000116484 Inula helenium Species 0.000 claims 1
- 235000002598 Inula helenium Nutrition 0.000 claims 1
- 235000006533 astragalus Nutrition 0.000 claims 1
- 210000000952 spleen Anatomy 0.000 abstract description 24
- 230000000694 effects Effects 0.000 abstract description 15
- 230000008901 benefit Effects 0.000 abstract description 7
- 230000001105 regulatory effect Effects 0.000 abstract description 6
- 210000001835 viscera Anatomy 0.000 abstract description 2
- 241000050051 Chelone glabra Species 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 description 14
- 230000000968 intestinal effect Effects 0.000 description 9
- 210000001035 gastrointestinal tract Anatomy 0.000 description 8
- 210000002429 large intestine Anatomy 0.000 description 8
- 230000001737 promoting effect Effects 0.000 description 8
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical group NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 230000007812 deficiency Effects 0.000 description 6
- 210000004072 lung Anatomy 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 6
- 230000004087 circulation Effects 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 231100000331 toxic Toxicity 0.000 description 5
- 230000002588 toxic effect Effects 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 230000035619 diuresis Effects 0.000 description 4
- 210000002216 heart Anatomy 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 208000004998 Abdominal Pain Diseases 0.000 description 3
- 102100024484 Codanin-1 Human genes 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 101000980888 Homo sapiens Codanin-1 Proteins 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 206010061876 Obstruction Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 210000000232 gallbladder Anatomy 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000009527 percussion Methods 0.000 description 3
- 238000010926 purge Methods 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 208000031481 Pathologic Constriction Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 208000033809 Suppuration Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000000172 allergic effect Effects 0.000 description 2
- 230000001174 ascending effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 235000019658 bitter taste Nutrition 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 206010016766 flatulence Diseases 0.000 description 2
- 238000007429 general method Methods 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 229960004963 mesalazine Drugs 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000008855 peristalsis Effects 0.000 description 2
- 238000002203 pretreatment Methods 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 230000036262 stenosis Effects 0.000 description 2
- 208000037804 stenosis Diseases 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 206010060921 Abdominal abscess Diseases 0.000 description 1
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 208000008710 Amebic Dysentery Diseases 0.000 description 1
- 206010001986 Amoebic dysentery Diseases 0.000 description 1
- 208000016583 Anus disease Diseases 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 244000247747 Coptis groenlandica Species 0.000 description 1
- 235000002991 Coptis groenlandica Nutrition 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 208000018672 Dilatation Diseases 0.000 description 1
- 206010013654 Drug abuse Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 206010058838 Enterocolitis infectious Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010016717 Fistula Diseases 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 206010018691 Granuloma Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 description 1
- 201000006347 Intellectual Disability Diseases 0.000 description 1
- 206010022699 Intestinal stenosis Diseases 0.000 description 1
- 206010074063 Ischaemic enteritis Diseases 0.000 description 1
- 206010034236 Pelvic abscess Diseases 0.000 description 1
- 206010056626 Pseudopolyp Diseases 0.000 description 1
- 208000015634 Rectal Neoplasms Diseases 0.000 description 1
- 206010038074 Rectal polyp Diseases 0.000 description 1
- 241000132004 Symphyotrichum cordifolium Species 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000035568 catharsis Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000000112 colonic effect Effects 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000003890 fistula Effects 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 230000001861 immunosuppressant effect Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000027139 infectious colitis Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000003243 intestinal obstruction Diseases 0.000 description 1
- 206010022694 intestinal perforation Diseases 0.000 description 1
- 201000008267 intestinal tuberculosis Diseases 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000009191 jumping Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- 229950010883 phencyclidine Drugs 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 208000022075 polyp of rectum Diseases 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 206010038038 rectal cancer Diseases 0.000 description 1
- 201000001275 rectum cancer Diseases 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000010079 rubber tapping Methods 0.000 description 1
- 201000004409 schistosomiasis Diseases 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease, which can effectively solve the problem of preparing medicines for treating abdominal distension caused by Crohn's disease, and the enema is prepared from the following raw materials by weight: 10-20g of costustoot, 15-20g of rhizoma cyperi, 10-20g of wrinkled gianthyssop herb, 9-15g of kudzuvine root, 12-15g of baical skullcap root, 12-15g of golden thread, 20-30g of purslane, 20-30g of heartleaf houttuynia herb, 6-9g of lithospermum and 15-20g of astragalus root, 400-600mL of water is added into the raw materials, the raw materials are soaked for 15-25 minutes at the temperature of 18-25 ℃, boiled with strong fire, decocted with slow fire for 20-30 minutes and filtered to obtain first filtrate; adding 400-600mL of water into the residue, boiling with strong fire, decocting with slow fire for 20-30min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing. The traditional Chinese medicine composition has the advantages of mutual support of the components, effects of regulating qi, clearing hollow viscera, invigorating spleen, clearing heat and eliminating dampness, effective treatment of abdominal distension caused by the Crohn disease, convenient use, safety and good effect, is an innovation of medicines for treating abdominal distension caused by the Crohn disease, has practical clinical application value and great economic and social benefits.
Description
Technical Field
The invention relates to a medicine, in particular to a traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease.
Background
Crohn's Disease (CD) is a kind of inflammatory bowel disease, and is mainly clinically manifested as abdominal distension, abdominal pain, diarrhea, and many cases with fever and other parenteral lesions such as joint, skin, eye, oral mucosa ulcer, etc. The western medicine mainly adopts glucocorticoid, immunosuppressant, biological agent (anti-TNF-alpha monoclonal antibody) and the like to induce and maintain relief, and the operation treatment has certain effect but treats the symptoms and the root causes.
In the attack stage of the Crohn's disease, spleen and stomach are damaged due to improper diet, exogenous pathogenic factors, emotional stimulation and the like, so that the spleen fails to transport and transport, phlegm dampness and dampness are generated internally, damp-heat is accumulated, qi and blood are stagnated, and the intestinal tract is damaged, so that the CD relapse is caused. Repeated CD attacks can aggravate spleen deficiency, so spleen deficiency is the cause of the CD attack and throughout the disease. Qi stagnation occurs when qi deficiency fails to promote the circulation due to stagnation in the middle energizer. Medical science is said in institute cloud: the right of ascending and descending is that in the middle-jiao qi, the spleen ascends and the stomach descends due to the hyperactivity of middle-jiao qi, the visceral manifestation is rotated in the wheel, and the spleen is depressed due to the failure of middle-jiao qi, leading to the adverse flow of stomach. Repeated CD attacks and damages the spleen and stomach, causing qi deficiency in the middle-jiao, qi stagnation, abnormal ascending and descending, obstruction of body fluids, accumulation of dampness. Besides affecting the middle energizer qi, weakness of the spleen and stomach also affects the qi movement of the intestines and fu organs. The small intestine secretes clear and turbid food, and the large intestine conducts dregs, both of which are smooth and depend on the descending and the passing of stomach qi, spleen deficiency causes the stagnation of qi in the middle energizer, stomach qi does not descend, qi deficiency drives weakness to cause the transmission and transformation of the large intestine, qi obstruction of the large intestine, and the functions of conducting and discharging dregs are reduced, thus the symptoms of abdominal distension, incomplete defecation and the like appear. Even if "pain, vomiting, distention and closure" occur, it is called "intestinal nodule". Among them, abdominal distension continues the longest in crohn's disease, most disturbing patients, and results in a decrease in the quality of life of patients. The treatment method of general reasons is preferably adopted. The narrow meaning of "general reasons" refers to the use of general-purpose drugs to treat some of the syndromes with the symptoms of diarrhea. Qing Dynasty Gaosheng Zhong Xin Tong Yun (medical science true biography, heart and abdominal pain): the general methods are different. Regulating qi to harmonize blood, regulating blood to harmonize qi, and dredging collaterals also. "further expand the thought connotation of the general method. The herbs with the actions of promoting qi circulation, clearing heat and eliminating dampness, and eliminating pathogens will strengthen the body resistance, make the spleen and stomach ascend and descend orderly, and regulate fu-qi. The cathartic medicine can be directly injected into large intestine of conductive organ without oral administration, and can accelerate catharsis and eliminate pathogenic factor. However, the traditional enema has large stimulation to intestinal tracts, unfixed and irregular medicine application and unsatisfactory use and curative effect, so that the development of a new medicine is imperative.
Disclosure of Invention
In view of the above situation, in order to overcome the defects of the prior art, the invention aims to provide a traditional Chinese medicine enema for treating the abdominal distension caused by the Crohn's disease, which can effectively solve the problem of preparing medicines for treating the abdominal distension caused by the Crohn's disease.
The invention solves the technical scheme that a traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease is prepared from the following raw material medicines in parts by weight: 10-20g of costustoot, 15-20g of rhizoma cyperi, 10-20g of wrinkled gianthyssop herb, 9-15g of kudzuvine root, 12-15g of baical skullcap root, 12-15g of golden thread, 20-30g of purslane, 20-30g of heartleaf houttuynia herb, 6-9g of lithospermum and 15-20g of astragalus root, 400-600mL of water is added into the raw materials, the raw materials are soaked for 15-25 minutes at the temperature of 18-25 ℃, boiled with strong fire, decocted with slow fire for 20-30 minutes and filtered to obtain first filtrate; adding 400-600mL of water into the residue, boiling with strong fire, decocting with slow fire for 20-30min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing.
The traditional Chinese medicine composition has the advantages of mutual support of the components, effects of regulating qi, clearing hollow viscera, invigorating spleen, clearing heat and eliminating dampness, effective treatment of abdominal distension caused by the Crohn disease, convenient use, safety and good effect, is an innovation of medicines for treating abdominal distension caused by the Crohn disease, has practical clinical application value and great economic and social benefits.
Detailed Description
The following examples and specific examples will explain the present invention in detail.
The invention is illustrated in the following examples.
Example 1
The invention relates to a traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease, which is prepared from the following raw materials in parts by weight: 15g of costustoot, 18g of rhizoma cyperi, 15g of wrinkled gianthyssop herb, 12g of kudzuvine root, 13g of baical skullcap root, 14g of golden thread, 25g of purslane, 25g of heartleaf houttuynia herb, 7g of lithospermum and 18g of astragalus root, 500mL of water is added into the raw materials, the raw materials are soaked for 15 to 25 minutes at the temperature of between 18 and 25 ℃, boiled with strong fire, decocted with slow fire for 25 minutes and filtered to obtain first filtrate; adding 500mL of water into the residue, boiling with strong fire, decocting with slow fire for 25min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing.
Example 2
The invention relates to a traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease, which is prepared from the following raw material medicines in parts by weight: 12g of costustoot, 19g of nutgrass galingale rhizome, 12g of wrinkled gianthyssop herb, 14g of kudzuvine root, 14g of baical skullcap root, 13g of golden thread, 22g of purslane, 28g of heartleaf houttuynia herb, 8g of sinkiang arnebia root and 16g of membranous milkvetch root, adding 550mL of water into the raw materials, soaking for 15-25 minutes at 18-25 ℃, boiling with strong fire, decocting with slow fire for 20min, and filtering to obtain first filtrate; adding 450mL of water into the residue, boiling with strong fire, decocting with slow fire for 30min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing.
Example 3
The invention relates to a traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease, which is prepared from the following raw materials in parts by weight: 18g of costustoot, 16g of nutgrass galingale rhizome, 18g of wrinkled gianthyssop herb, 10g of kudzuvine root, 13g of baical skullcap root, 14g of golden thread, 28g of purslane, 22g of heartleaf houttuynia herb, 9g of sinkiang arnebia root and 19g of membranous milkvetch root, adding 600mL of water into the raw materials, soaking for 15-25 minutes at 18-25 ℃, boiling with strong fire, decocting with slow fire for 30min, and filtering to obtain first filtrate; adding 400mL of water into the residue, boiling with strong fire, decocting with slow fire for 20min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing.
In the above medicament, wherein:
costustoot: pungent, bitter and warm, entering spleen, stomach, large intestine, triple energizer and gallbladder meridians, moving qi and relieving pain, invigorating spleen and promoting digestion.
Rhizoma cyperi: pungent, slightly bitter, slightly sweet and neutral, enter liver, spleen and triple energizer meridians, move qi and relieve depression, regulate menstruation and alleviate pain.
Agastache rugosus: pungent flavor, warm nature, entering spleen, stomach and lung meridians, resolving dampness and enlivening spleen, removing filth and regulating the middle warmer, relieving summer-heat, relieving exterior syndrome.
Kudzu root: sweet and pungent in flavor, cool in nature, entering lung and stomach meridians, expelling pathogenic factors from muscles and skin, bringing down fever, promoting eruption, promoting the production of body fluid to quench thirst, invigorating yang and relieving diarrhea.
Scutellaria baicalensis: bitter taste and cold nature, entering lung, gallbladder, spleen, large intestine and small intestine channels, clearing heat and drying dampness, purging fire and removing toxicity, stopping bleeding and preventing miscarriage.
Coptis root: bitter taste and cold nature, and they enter heart, spleen, stomach, liver, gallbladder and large intestine meridians. Clear heat and dry dampness, purge fire and remove toxicity.
Purslane: sour and cold, entering liver and large intestine meridians, clearing away heat and toxic material, cooling blood and arresting bleeding, and stopping dysentery.
Heartleaf houttuynia herb: pungent and slightly cold in property, entering lung and bladder meridians, not only can clear away heat and toxic material, cure abscess, expel pus, induce diuresis and treat stranguria, but also integrates the actions of clearing heat and relieving, expelling pus, inducing diuresis and expelling superficial evils.
Lithospermum: sweet, salty and cold in nature and taste. It enters heart and liver meridians. Has the functions of cooling blood, promoting blood circulation, detoxicating and promoting eruption.
Astragalus root: sweet in flavor and slightly warm in nature; it enters spleen and lung meridians. Invigorate spleen, strengthen middle energizer, raise yang, lift sinking, benefit wei-defensive qi to consolidate superficial, induce diuresis, expel toxin and promote tissue regeneration.
The medicinal components support and cooperate with each other. Radix aucklandiae and rhizoma Cyperi can promote the circulation of qi of the intestines and fu, compendium of materia Medica cloud: rhizoma Cyperi and radix aucklandiae have effects of resolving stagnation and regulating the middle warmer; the three herbs are monarch drugs which are used together to help dredge qi movement of spleen, stomach and intestines; the kudzu vine root, the baical skullcap root and the golden thread are used as ministerial medicaments for clearing heat, promoting diuresis and treating the symptoms; the purslane, the houttuynia cordata and the lithospermum are used as adjuvant drugs to help clear away heat and toxic materials and remove damp-heat and turbid-toxin; astragalus root, radix astragali is a guiding drug, helps to invigorate qi and spleen, and promotes qi circulation when spleen and stomach are healthy and healthy, so that damp pathogen can not be generated. The whole formula has the effects of promoting the circulation of qi, removing food retention, relaxing bowels and purging heat, is effectively used for treating the abdominal distension caused by the Crohn's disease, and obtains very good beneficial effects through experiments, and the related data are as follows:
1. general data: 65 patients with Crohn's disease and abdominal distension were diagnosed from the 12 th month of 2016 to the 12 th month of 2021 in the outpatient service and ward. Is divided into traditional Chinese medicine group and mesalazine group at random. 33 cases, 18 cases and 15 cases of men and women in the traditional Chinese medicine (namely the invention group, the same below); the largest age is 59 years, the smallest is 20 years. Mesalazine group 32, 19 men, and 13 women; the largest age is 58 years, the smallest age is 21 years.
2. Criteria for selecting cases:
patients with crohn's disease often have abdominal bloating, which is associated with the following factors:
intestinal canal obstruction: patients with crohn's disease have transmural inflammation of the intestinal tract, intestinal stenosis, and often develop intestinal flatulence after eating;
intestinal inflammation: can affect the peristalsis of the intestinal tract, and when the peristalsis of the intestinal tract is slow, the patient can have flatulence.
Intestinal microecological changes: the abdominal distension of patients with Crohn's disease is a common manifestation because the patients with Crohn's disease have severe intestinal inflammation, intestinal microecological disorder, decreased intestinal beneficial bacteria and increased harmful bacteria, which often include aerogenic bacilli, and the aerogenic bacilli cause abdominal distension of the patients.
All patients with the above symptoms can be used as the criteria for selecting cases.
3. Diagnostic criteria (established with reference to the criteria for crohn's disease recommended by the world health organization in 2014): (1) typical clinical symptoms. (2) And X-ray shows gastrointestinal tract fissure-shaped ulcer, cobblestone sign, pseudopolyp, multiple stenosis, fistula formation and the like. The lesions are distributed in segments. CT may show loops with thickened intestinal walls, pelvic or abdominal abscesses. (3) And longitudinal or creeping ulcers with jumping distribution are seen under the endoscope, and the surrounding mucous membrane is normal or proliferated like pebbles. (4) Non-caseous necrotic granuloma, or massive lymphocyte accumulation in lesion biopsies.
4. Inclusion criteria
(1) The standard for the diagnosis of Crohn's disease is met and the clinical severity is mild to moderate patients. (according to international CDAI scores, scores were mild from 150-275, moderate from 275-450, and scores greater than 450 were severe. Mild and moderate patients were included in this study, and severe patients were excluded), the CDAI scoring system included 8 dimensions: the number of bowel movements per day in the past 1 week, daily abdominal pain conditions (none =0,2, weight = 3), daily general health (health =0 requires the administration of phencyclidine/opioid (none =0 product, (standard body mass-actual body mass)/standard body mass.1 week observation was made for the above 8 dimensions, multiplied by the corresponding weights, and the sum of the 8 scores was the total score of the CDAI.
(2) The age is 18-65 years old, and the nature is not limited.
5. Exclusion criteria
(1) The disease condition is severe.
(2) Infectious colitis such as bacillary dysentery, amebic dysentery, chronic schistosomiasis, and intestinal tuberculosis, and patients with ulcerative colitis, ischemic enteritis, and radiation enteritis.
(3) Patients with severe complications such as local stenosis, intestinal obstruction, intestinal perforation, rectal polyp, toxic colonic dilatation, colon cancer, rectal cancer and anal disease
(4) Pregnant and lactating women.
(5) Those with severe primary heart, liver, lung, kidney, blood or severe disease affecting their survival.
(6) Disabled patients as prescribed by law (blind, deaf, dumb, intellectual disability, mental disorder, physical disability).
(7) Suspected or definite history of alcohol, drug abuse.
(8) According to the judgment of researchers, other diseases which reduce the possibility of entering the group or complicate the group exist, such as the condition that the working environment is frequently changed and the like, which is easy to cause missed visits.
(9) Allergic constitution, e.g. a history of allergy to two or more drugs or food; or one known to be allergic to the present drug ingredients.
6. The treatment scheme comprises the following steps:
the traditional Chinese medicine is prepared by 400mL of the traditional Chinese medicine enema (taking the example 1 as an example), and the enema is kept for 1 time every night, and 14 days are a treatment course. The curative effect is judged by observing two courses of treatment.
The mesalazine group is orally taken 3 times a day by 4 mesalazine tablets. The treatment course is the same as the traditional Chinese medicine.
6.1 Grading standard of abdominal distension:
degree I (mild): a swollen abdomen, slightly higher than the chest, is soft. Percussion presents a bass drum sound. Bowel sounds may be attenuated, slightly accentuated or normal. Slight abdominal distension may occur.
II degree (moderate degree), the abdomen is raised obviously higher than the chest, and has certain tension. Percussion presents the middle-tone drum sound, and the range and intensity are both increased and obvious. Bowel sounds are often attenuated, and voluntary abdominal distension is obvious, affecting food intake or other metabolism.
Degree III (severe): the whole abdomen is obviously raised and spherical, and the pressure is hard and uncomfortable without rebound pain. The percussion is a high-pitched drum sound, and can generate metal tapping sound without any change along with the body position. The bowel sound is obviously weakened or disappeared, the intestinal tract reaction is obvious when the intestinal tract sound is heard and smells over water.
And the efficacy was judged by the following formula:
the therapeutic effect determination value = pre-treatment integral-post-treatment integral/pre-treatment integral × 100%
The therapeutic criteria are as follows: the effect is shown: decision value >2/3, valid: 1/3< decision value <2/3, invalid: the decision value is <1/3.
TABLE 1 comparison of the total effective rates of the Chinese medicinal formula group and the mesalazine group
| Group of | Number of examples | Show effect | Is effective | Nullification | Effective rate% |
| Chinese medicine | 33 | 10 | 21 | 2 | 93.9 |
| Mesalazine group | 32 | 7 | 15 | 10 | 68.7* |
Note: * P < 0.05
The total effective rate of the traditional Chinese medicine is 93.9 percent, is obviously superior to the total effective rate of the mesalazine group (68.7 percent), and has obvious difference (P is less than 0.05) after statistical treatment.
The same or similar results were obtained in the examples 1 and other examples, which are not listed here.
Experiments show that the traditional Chinese medicine enema prepared by the invention has stable and reliable curative effect on the abdominal distension caused by the Crohn disease, no obvious toxic or side effect, safe medication, stable and reliable curative effect, and the curative effect of 93.9 percent, has obvious advantages in treatment compared with the existing medicines, has very strong clinical use value, is innovation on the medicines for treating the abdominal distension caused by the Crohn disease, and has huge economic and social benefits.
Claims (4)
1. A traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease is characterized by being prepared from the following raw material medicines in parts by weight: 10-20g of elecampane, 15-20g of rhizoma cyperi, 10-20g of agastache rugosus, 9-15g of radix puerariae, 12-15g of scutellaria baicalensis, 12-15g of coptis chinensis, 20-30g of purslane, 20-30g of houttuynia cordata, 6-9g of lithospermum and 15-20g of astragalus membranaceus, 400-600mL of water is added into the raw materials, the raw materials are soaked for 15-25 minutes at the temperature of 18-25 ℃, boiled by strong fire, decocted for 20-30 minutes by slow fire and filtered to obtain first filtrate; adding 400-600mL of water into the residue, boiling with strong fire, decocting with slow fire for 20-30min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing.
2. The traditional Chinese medicine enema for treating Crohn's disease abdominal distension according to claim 1, which is prepared from the following raw materials in parts by weight: 15g of costustoot, 18g of rhizoma cyperi, 15g of wrinkled gianthyssop herb, 12g of kudzuvine root, 13g of baical skullcap root, 14g of golden thread, 25g of purslane, 25g of heartleaf houttuynia herb, 7g of lithospermum and 18g of astragalus root, 500mL of water is added into the raw materials, the raw materials are soaked for 15 to 25 minutes at the temperature of between 18 and 25 ℃, boiled with strong fire, decocted with slow fire for 25 minutes and filtered to obtain first filtrate; adding 500mL of water into the residue, boiling with strong fire, decocting with slow fire for 25min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing.
3. The traditional Chinese medicine enema for treating Crohn's disease abdominal distension according to claim 1, which is prepared from the following raw materials in parts by weight: 12g of costustoot, 19g of nutgrass galingale rhizome, 12g of wrinkled gianthyssop herb, 14g of kudzuvine root, 14g of baical skullcap root, 13g of golden thread, 22g of purslane, 28g of heartleaf houttuynia herb, 8g of sinkiang arnebia root and 16g of membranous milkvetch root, adding 550mL of water into the raw materials, soaking for 15-25 minutes at 18-25 ℃, boiling with strong fire, decocting with slow fire for 20min, and filtering to obtain first filtrate; adding 450mL of water into the residue, boiling with strong fire, decocting with slow fire for 30min, filtering to obtain the second filtrate, mixing the two filtrates, and mixing.
4. The traditional Chinese medicine enema for treating Crohn's disease abdominal distension according to claim 1, which is prepared from the following raw materials in parts by weight: 18g of costustoot, 16g of nutgrass galingale rhizome, 18g of wrinkled gianthyssop herb, 10g of kudzuvine root, 13g of baical skullcap root, 14g of golden thread, 28g of purslane, 22g of heartleaf houttuynia herb, 9g of sinkiang arnebia root and 19g of membranous milkvetch root, adding 600mL of water into the raw materials, soaking for 15-25 minutes at 18-25 ℃, boiling with strong fire, decocting with slow fire for 30min, and filtering to obtain first filtrate; adding 400mL of water into the medicine residues, boiling with strong fire, decocting with slow fire for 20min, filtering to obtain a second filtrate, combining the two filtrates, and mixing uniformly to obtain the traditional Chinese medicine composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211417558.0A CN115501169A (en) | 2022-11-14 | 2022-11-14 | Traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211417558.0A CN115501169A (en) | 2022-11-14 | 2022-11-14 | Traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115501169A true CN115501169A (en) | 2022-12-23 |
Family
ID=84513813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211417558.0A Pending CN115501169A (en) | 2022-11-14 | 2022-11-14 | Traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115501169A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117180361A (en) * | 2023-10-20 | 2023-12-08 | 河南中医药大学 | Traditional Chinese medicine for treating spleen deficiency and qi stagnation combined with damp-heat type ulcerative colitis |
-
2022
- 2022-11-14 CN CN202211417558.0A patent/CN115501169A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117180361A (en) * | 2023-10-20 | 2023-12-08 | 河南中医药大学 | Traditional Chinese medicine for treating spleen deficiency and qi stagnation combined with damp-heat type ulcerative colitis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101757386B (en) | Preparation method of traditional Chinese medicine for treating infantile capillary bronchitis | |
| CN102188685B (en) | Externally-applied traditional Chinese medicine powder for treating diarrhea type irritable bowel syndrome and preparation method thereof | |
| CN103520680A (en) | Traditional Chinese medicine for treating acute heart failure | |
| CN115501169A (en) | Traditional Chinese medicine enema for treating abdominal distension caused by Crohn's disease | |
| CN102319353B (en) | Traditional Chinese drug enema for treating abdominal distension after gynecological operation | |
| CN104258289A (en) | Traditional Chinese medicine for treating enteritis | |
| CN105920534A (en) | Traditional Chinese medicine composition for treating digestive tract malignant tumors and preparation of composition | |
| CN111135239A (en) | Traditional Chinese medicine enema for treating Crohn's disease | |
| CN104547698A (en) | Traditional Chinese medicine preparation for painless treatment of haemorrhoids and preparation method thereof | |
| CN102886016B (en) | Traditional Chinese medicine preparation for treating cholecystic polypus | |
| CN104306793A (en) | Chinese herba preparation for treating lobar pneumonia | |
| CN113144067A (en) | Traditional Chinese medicine decoction for treating Crohn's disease | |
| CN105395975A (en) | Enema traditional Chinese medicine composition treating ulcerative colitis and preparation method thereof | |
| CN105327171A (en) | Traditional Chinese medicine electuary for treating mastitis and preparing method thereof | |
| CN113633748B (en) | Medicine for treating spontaneous bacterial peritonitis damp-heat stasis syndrome of liver cirrhosis and preparation method thereof | |
| CN1277558C (en) | Chinese traditional medicine preparation for treating chronic enteritis, colitis and proctitis | |
| CN104127827A (en) | Traditional Chinese medicine for treating biliary calculi | |
| CN115554374B (en) | Traditional Chinese medicine composition for treating helicobacter pylori gastritis as well as preparation method and application thereof | |
| CN114191528B (en) | Traditional Chinese medicine composition for treating cholelithiasis and preparation method and application thereof | |
| CN102698126B (en) | Traditional Chinese medicine compound having effect of treating prostatitis and preparation method thereof | |
| CN106491974B (en) | Traditional Chinese medicine composition and traditional Chinese medicine decoction for treating enteroparalysis | |
| CN113876875A (en) | Traditional Chinese medicine enema for treating abdominal pain of Crohn's disease | |
| Xu | TCM and Western Medicine: Diagnosis and Treatment of Novel Coronavirus Pneumonia, A Case Study | |
| CN117883536A (en) | Traditional Chinese medicine composition for treating intestinal inflammation and cancer transformation diseases and application thereof | |
| CN104689253A (en) | Traditional Chinese medicine composition for treating gallbladder removal syndromes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |