CN115475232A - 抗微生物肽及其使用方法 - Google Patents

抗微生物肽及其使用方法 Download PDF

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Publication number
CN115475232A
CN115475232A CN202211040273.XA CN202211040273A CN115475232A CN 115475232 A CN115475232 A CN 115475232A CN 202211040273 A CN202211040273 A CN 202211040273A CN 115475232 A CN115475232 A CN 115475232A
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CN
China
Prior art keywords
antimicrobial
composition
amino acid
pharmaceutical composition
antimicrobial composition
Prior art date
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Pending
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CN202211040273.XA
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English (en)
Chinese (zh)
Inventor
杰西·杰尼斯
L·爱德华·克莱门斯
亨利·W·洛佩兹
乔治·R·马丁
凯瑟琳·伍德伯恩
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Riptide Bioscience Inc
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Riptide Bioscience Inc
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Publication of CN115475232A publication Critical patent/CN115475232A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
CN202211040273.XA 2015-03-23 2016-03-23 抗微生物肽及其使用方法 Pending CN115475232A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562137206P 2015-03-23 2015-03-23
US62/137,206 2015-03-23
PCT/US2016/023801 WO2016154328A2 (en) 2015-03-23 2016-03-23 Antimicrobial peptides and methods of use thereof
CN201680025771.3A CN107614004B (zh) 2015-03-23 2016-03-23 抗微生物肽及其使用方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201680025771.3A Division CN107614004B (zh) 2015-03-23 2016-03-23 抗微生物肽及其使用方法

Publications (1)

Publication Number Publication Date
CN115475232A true CN115475232A (zh) 2022-12-16

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Family Applications (2)

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CN202211040273.XA Pending CN115475232A (zh) 2015-03-23 2016-03-23 抗微生物肽及其使用方法
CN201680025771.3A Active CN107614004B (zh) 2015-03-23 2016-03-23 抗微生物肽及其使用方法

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Country Status (8)

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US (2) US10017542B2 (https=)
EP (2) EP3903823A3 (https=)
JP (2) JP6964577B2 (https=)
KR (1) KR20180002618A (https=)
CN (2) CN115475232A (https=)
AU (2) AU2016235147B2 (https=)
CA (1) CA2981705A1 (https=)
WO (1) WO2016154328A2 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180002618A (ko) * 2015-03-23 2018-01-08 립타이드 바이오사이언스, 인코포레이티드 항균 펩티드 및 이의 사용방법
US20200131231A1 (en) 2017-02-17 2020-04-30 Oxford University Innovation Limited Cell penetrating peptides
GB201812972D0 (en) 2018-08-09 2018-09-26 Univ Oxford Innovation Ltd Cell-penetrating peptides
GB201812980D0 (en) 2018-08-09 2018-09-26 Univ Oxford Innovation Ltd Cell-penetrating peptides
WO2020046297A2 (en) * 2018-08-29 2020-03-05 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
US10413584B1 (en) 2018-08-29 2019-09-17 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
US20200102356A1 (en) * 2018-10-01 2020-04-02 NMC Inc. Compositions and Methods for the Treatment of Huanglongbing (HLB) aka Citrus Greening in Citrus Plants
US10548944B1 (en) * 2018-10-19 2020-02-04 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same
CN113226349A (zh) * 2018-10-19 2021-08-06 激流生物科学有限公司 抗微生物肽及其使用方法
CN113453723A (zh) 2018-12-07 2021-09-28 牛津大学科技创新有限公司 接头
WO2020199202A1 (zh) * 2019-04-04 2020-10-08 林翰佳 碳量子点及其用途
JP2022527133A (ja) 2019-04-12 2022-05-30 リップタイド バイオサイエンス インコーポレイテッド マクロファージの活性を調節する方法
CN110305193B (zh) * 2019-07-18 2021-10-08 河南科技大学 一种抗牙龈卟啉单胞菌多肽及应用
US20230147468A1 (en) * 2020-03-31 2023-05-11 Innate Immunity LLC Recombinant peptide to treat fire blight
JP7717797B2 (ja) * 2021-09-03 2025-08-04 深▲セン▼千越生物科技有限公司 抗菌ペプチド又はペプチド誘導体、置換体及びその組成物、製造方法及び応用
CN114989254B (zh) * 2022-06-17 2023-11-03 中山大学 一种多肽及其设计方法和在制备抑制具核梭杆菌产品或预防结直肠癌药物中的应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1040033A (zh) * 1988-05-27 1990-02-28 麦盖宁科学有限公司 两亲肽及其用途
US20080153748A1 (en) * 2006-12-21 2008-06-26 Jaynes Corporation Novel molecules for the treatment and privention of fungal diseases
CN103403153A (zh) * 2010-12-23 2013-11-20 莱桑多公司 抗微生物制剂
US20140128312A1 (en) * 2010-06-29 2014-05-08 Jesse Michael Jaynes Antimicrobial lytic peptides
CN107614004A (zh) * 2015-03-23 2018-01-19 激流生物科学有限公司 抗微生物肽及其使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69034085T2 (de) * 1989-04-10 2004-05-27 Helix BioMedix, Inc., Bothell Lytsche und proliferative Peptide und deren Verwendung als Pharmaka und Phytopharmaka
US5561107A (en) * 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
IL114697A0 (en) * 1994-07-22 1995-11-27 Demeter Biotech Ltd Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use
JPH08134075A (ja) * 1994-11-02 1996-05-28 Yamanouchi Pharmaceut Co Ltd 新規なカルバペネム誘導体
KR19990082383A (ko) * 1996-02-16 1999-11-25 스티븐슨 린다 에스. 항균성 펩티드 및 이의 사용법
JP2001501620A (ja) * 1996-10-04 2001-02-06 デメジェン インコーポレイテッド 免疫不全ウイルス感染の治療方法
US6680058B1 (en) * 1997-09-03 2004-01-20 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions and methods for contraception in or sterilization of mammals
JP2003509010A (ja) * 1999-05-31 2003-03-11 ノボザイムス アクティーゼルスカブ ペプチドのスクリーニング方法
US6432415B1 (en) * 1999-12-17 2002-08-13 Axrix Laboratories, Inc. Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces
AU2003269851A1 (en) * 2002-10-09 2004-05-04 Novozymes A/S A method for screening for an antimicrobial polypeptide
CA2655448C (en) * 2005-12-22 2016-09-06 Novabiotics Limited Cyclic antimicrobial peptides
NZ571989A (en) * 2006-03-23 2012-07-27 Agriculture Victoria Serv Pty Antimicrobial protein
NZ572376A (en) * 2006-05-16 2011-10-28 Dermagen Ab Improved antimicrobial peptides
US7288622B1 (en) * 2006-09-19 2007-10-30 Issar Pharmaceuticals Pvt Ltd Composition for treatment of burns and wounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1040033A (zh) * 1988-05-27 1990-02-28 麦盖宁科学有限公司 两亲肽及其用途
US20080153748A1 (en) * 2006-12-21 2008-06-26 Jaynes Corporation Novel molecules for the treatment and privention of fungal diseases
US20140128312A1 (en) * 2010-06-29 2014-05-08 Jesse Michael Jaynes Antimicrobial lytic peptides
CN103403153A (zh) * 2010-12-23 2013-11-20 莱桑多公司 抗微生物制剂
CN107614004A (zh) * 2015-03-23 2018-01-19 激流生物科学有限公司 抗微生物肽及其使用方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陈宇婷;王长海;严秀文;黎军胜;: "抗菌肽的设计及其应用", 中国生物工程杂志, no. 07, 15 July 2013 (2013-07-15), pages 97 - 102 *

Also Published As

Publication number Publication date
KR20180002618A (ko) 2018-01-08
JP7267251B2 (ja) 2023-05-01
WO2016154328A2 (en) 2016-09-29
EP3903823A2 (en) 2021-11-03
EP3274472B1 (en) 2020-09-23
AU2019222918B2 (en) 2021-10-21
US20160296594A1 (en) 2016-10-13
JP2018512454A (ja) 2018-05-17
AU2016235147A1 (en) 2017-10-26
EP3903823A3 (en) 2022-02-23
EP3274472A4 (en) 2018-12-05
CA2981705A1 (en) 2016-09-29
AU2016235147B2 (en) 2019-09-19
US10017542B2 (en) 2018-07-10
CN107614004A (zh) 2018-01-19
US20190071470A1 (en) 2019-03-07
EP3274472A2 (en) 2018-01-31
JP6964577B2 (ja) 2021-11-10
CN107614004B (zh) 2022-12-06
AU2019222918A1 (en) 2019-09-19
JP2021054842A (ja) 2021-04-08

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Application publication date: 20221216