CN115475136A - Biological product for slowing body skin neutralization aging rate - Google Patents
Biological product for slowing body skin neutralization aging rate Download PDFInfo
- Publication number
- CN115475136A CN115475136A CN202211285429.0A CN202211285429A CN115475136A CN 115475136 A CN115475136 A CN 115475136A CN 202211285429 A CN202211285429 A CN 202211285429A CN 115475136 A CN115475136 A CN 115475136A
- Authority
- CN
- China
- Prior art keywords
- skin
- product
- neutralization
- body skin
- aging
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a biological product for slowing down the neutralization aging rate of body skin, which is prepared from the following raw materials in parts by weight, 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-100 g of sodium alginate; the invention makes animal pancreas, animal thymus, papain and sodium alginate into paste, freeze-dried powder or other forms. The biological product is independently used for body skin, can deeply clean three metabolism barrier garbage of the skin, permeate the skin, smooth the three metabolism, hydrate and moisten the skin, improve the skin lipoid metabolism level and slow down the rate of body skin neutralization and aging.
Description
Technical Field
The invention belongs to the field of human skin aging resistance, and particularly relates to a biological product for slowing down the rate of neutralization and aging of body skin.
Background
At present, some products such as cleaning products, skin care products, moisturizing products and the like exist in the cosmetic categories at home and abroad, but the products only play a role in beautifying the life of the skin and do not slow down the skin neutralization rate outside the body.
At present, the problems that the skin is seriously polluted repeatedly in the deep layer, three metabolism (gas metabolism, liquid metabolism and solid metabolism) passages of the skin are seriously blocked, the skin is neutralized in advance and the like cannot be solved for the skin outside the body at home and abroad, and the skin appearance damage mainly comes from three aspects, one is the influence of the reproductive system in the body; secondly, the influence of three major metabolism of the body skin; and the third is the influence of pollution or damage caused by the natural environment. All three factors directly contribute to accelerating the skin towards neutrality.
Although the skin cleaning products, the skin nursing products and the skin moisturizing products sold on the market at present and various medicines related to the skin have the functions, no product can be used for clearing the three skin metabolisms, ensuring the three skin metabolisms to be smooth and leading the skin to be transparent, and further the problem of slowing down the skin neutralization process is solved. Therefore, the development of a natural biological cosmetic product which can effectively clean the skin, promote three metabolism of the skin outside the body to be smooth and slow down the skin neutralization and aging rate is particularly necessary.
Disclosure of Invention
The biological product has the biological effects of deeply cleaning barrier garbage of three major metabolisms of the skin, enabling the skin to be permeable and smooth, enabling skin cells to be hydrated and moist, improving the skin lipoid metabolism level and slowing down the rate of neutralization of the natural aging of the body skin.
In order to achieve the purpose, the technical scheme of the invention is that the biological product for slowing down the neutralization aging rate of body skin is prepared from the following raw materials in parts by weight: 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-150 g of sodium alginate.
The preparation method comprises the following steps:
firstly, crushing pancreas and thymus gland slices by a meat grinder, adding an ethanol solution of 3% peracetic acid by mass, and soaking for 10 hours at room temperature;
step two, adding purified water with the mass of 2.5 times of that of the mixture treated in the step one, and pulping by using a colloid mill; adding polylysine, potassium sorbate, calcium propionate and sodium propionate, stirring uniformly, slowly heating to 20-25 ℃, heating for 8 hours, and removing connective tissues by using an 80-mesh screen to obtain pancreas and thymus mixed feed liquid;
step three, adding papain into the mixture liquid obtained in the step two, and stirring and mixing uniformly to obtain a mixed liquid;
step four, preparing sodium alginate into a solution with the content of 1.5% by using purified water, adding the solution into the mixed feed liquid obtained in the step three, and uniformly stirring to obtain an ointment, namely the biological product for slowing down the body skin neutralization aging.
The invention has the following beneficial effects:
1. the present invention features that animal's pancreas and thymus are used as material and the product is prepared through soaking, grinding and low temperature preparation, and contains pancreatin, thymus peptide, polypeptide, polysaccharide, lipopolysaccharide, lipoprotein, etc.
2. The second characteristic of the invention is that the ingredients contained in the product have biodegradability.
3 the use observations of the inventive article show that: the pancreatin in the product can degrade the stratum corneum metabolized by the skin and die the cast-off cells, plays a biological role in cleaning and permeating the skin, and promotes smooth metabolism of the three parts of the skin; meanwhile, the thymosin, various polypeptides, polysaccharides, lipopolysaccharides and lipoprotein have the biological effects of moisturizing the skin, and the phenomenon of neutralization of the body skin is obviously slowed down after long-term use.
Detailed Description
The present invention is further illustrated by the following examples, which include, but are not limited to, the following examples.
A biological product for slowing the rate of neutralization and aging of body skin is prepared from the following raw materials in parts by weight: 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-100 g of sodium alginate.
Example 1
A biological product for slowing the rate of neutralization aging of body skin comprises the following substances in parts by weight: 1000g of animal pancreas, 1000g of animal thymus, 35g of papain and 30g of sodium alginate. The preparation method comprises the following steps:
the method comprises the following steps: mixing animal pancreas and thymus slice, crushing, adding 3% ethanol solution of peroxyacetic acid, and soaking at low temperature for 8 hr;
step two: adding purified water with the mass of 2.5 times of that of the mixture treated in the first step into the mixture, and pulping by using a colloid mill;
step three: adding 48g (content: 0.6%) of polylysine, 48g (content: 0.6%) of potassium sorbate, 80g (content: 1%) of calcium propionate and 80g (content: 1%) of sodium propionate into the serous fluid obtained in the second step, uniformly stirring, slowly heating to 20-25 ℃, wherein the heating time is 8 hours, and then removing connective tissues by using a 80-mesh screen to obtain pancreas and thymus mixed fluid;
step four: adding papain into the mixture liquid obtained in the third step, and uniformly stirring to obtain a mixture liquid;
step five: preparing sodium alginate solution with 1.5% pure water; adding 1.5 percent of 2L sodium alginate solution into the mixture liquid obtained in the fourth step, and uniformly stirring to obtain paste;
step six: and D, directly subpackaging the paste obtained in the step five into paste products, or freezing at low temperature to obtain frozen products.
Example 2
A biological product for slowing the rate of neutralization aging of body skin comprises the following substances in parts by weight: 1500g of pancreas, 1000g of thymus, 40g of papain and 40g of sodium alginate; the preparation method comprises the following steps:
the method comprises the following steps: mixing pancreas and thymus gland sliced sheet, crushing, adding 3% ethanol solution of peroxyacetic acid, and soaking at low temperature for 10 hr;
step two: adding purified water with the mass of 3 times into the mixture treated in the first step, and pulping by using a colloid mill;
step three: adding 55g (content: 0.5%) of polylysine, 55g (content: 0.5%) of potassium sorbate, 55g (content: 0.5%) of calcium propionate and 55g (content: 0.5%) of sodium propionate into the slurry obtained in the second step, uniformly stirring, slowly heating to 20-25 ℃, wherein the heating time is 10h, and then removing connective tissues by using an 80-mesh screen to obtain a pancreas and thymus mixed feed liquid;
step four: adding papain into the mixture liquid obtained in the third step, and uniformly stirring to obtain a mixed liquid;
step five: preparing sodium alginate solution with the content of 1.5% by using purified water, adding 1.5% of 2.7L of sodium alginate solution into the mixture liquid obtained in the fourth step, and uniformly stirring to obtain product paste;
step six: and D, directly packaging the product paste obtained in the step five into paste products, or freezing the product paste at low temperature to obtain frozen products.
Example 3
A biological product for slowing the rate of neutralization aging of body skin comprises the following substances in parts by weight: 2000g of pancreas, 2500g of thymus, 100g of papain and 75g of sodium alginate; the preparation method comprises the following steps:
the method comprises the following steps: mixing pancreas and thymus gland sliced sheet, crushing, adding 3% ethanol solution of peroxyacetic acid, and soaking at low temperature for 10 hr;
step two: adding purified water with the mass of 2.5 times of that of the mixture treated in the first step into the mixture, and pulping by using a colloid mill;
step three: adding 128g (content: 0.8%) of polylysine, 128g (content: 0.8%) of potassium sorbate, 32g (content: 0.2%) of calcium propionate and 32g (content: 0.2%) of sodium propionate into the serous fluid obtained in the second step, uniformly stirring, slowly heating to 20-25 ℃, heating for 10 hours, and then removing connective tissues by using a 80-mesh screen to obtain a pancreas and thymus mixed fluid;
step four: adding papain into the mixture liquid obtained in the third step, and uniformly stirring to obtain a mixed liquid;
step five: preparing sodium alginate into a solution with the content of 1.5% by using purified water, adding a 5.0L sodium alginate solution with the content of 1.5% into the mixture liquid obtained in the fourth step, and uniformly stirring to obtain a product paste;
step six: and D, directly packaging the product paste obtained in the step five into paste products, or freezing the product paste at low temperature to obtain frozen products.
Example 4
The product pastes prepared in examples 1-3 were tested for the stratum corneum catabolism of skin, according to the test methods shown in table 1:
table 1: examples 1-3 skin cleaning test of preparations
| Categories | Example 1 | Example 2 | Example 3 |
| Amount of product put in | 1g | 1g | 1g |
| The sheet stratum corneum is more than or equal to 20 meshes | 0.1g | 0.1g | 0.1g |
| Constant volume | 100ml | 100ml | 100ml |
| Temperature of | 25℃ | 25℃ | 25℃ |
| Time of stirring | 15 minutes | 15 minutes | 15 minutes |
| Filtering with 100 mesh screen | The screen mesh is free of impurities | The screen mesh is free of impurities | The screen mesh is free of impurities |
| Conclusion | Complete decomposition | Complete decomposition | Complete decomposition |
Example 5
The product paste prepared in the examples 1-3 is subjected to a skin water metabolism influence test, and the test method adopts a comparison method: one hand and the small arm are cleaned by 3g of the product paste prepared in the examples 1 to 3 in a way that the product paste is mixed with a proper amount of water, the product paste is smeared and massaged for 8 to 10 minutes and then is washed clean by clear water, the cleaned and dried hand and the small arm and the uncleaned other hand and the small arm are respectively sleeved by two plastic sleeves, 2g of water-absorbing color-changing silica gel is respectively put into the sleeves, and the sleeves are sealed by sealing glue. The test conditions were controlled to be constant at room temperature of 30 ℃, the timing was started when the color-changing silica gel was placed, the color-changing time was accurately observed and recorded, and the results are shown in table 2. The interval of 12 months was again determined as described above (the subjects involved in the experiment used this product on average 2 times per week between 12 months).
Table 2: examples 1-3 skin cleaning test of preparations
Remarking: the measuring environment temperature is 30 ℃, the color change time is 5 average time values, the number of people in each age group is 5, the color change time 1 is the determined age, and the color change time 2 is the measuring result after the color change time 1 is separated by 12 months.
The above description is only an embodiment of the present invention with excellent effect and expression, and is not intended to limit the present invention, and it is obvious to those skilled in the art that various modifications and variations can be made in the present invention. Any modification, equivalent replacement or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (3)
1. A biological product for slowing the rate of neutralization and aging of body skin is characterized by comprising the following raw materials in parts by weight: 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-100 g of sodium alginate;
the preparation method comprises the following steps:
firstly, crushing pancreas and thymus gland slices by a meat grinder, adding an ethanol solution of 3% peracetic acid by mass, and soaking for 10 hours at room temperature;
step two, adding purified water with the mass of 2.5 times of that of the mixture treated in the step one, and pulping by using a colloid mill; adding polylysine, potassium sorbate, calcium propionate and sodium propionate, stirring uniformly, slowly heating to 20-25 deg.C for 8 hr, and removing connective tissue with 80 mesh sieve to obtain mixed pancreas and thymus feed liquid;
step three, adding papain into the mixture liquid obtained in the step two, and stirring and mixing uniformly to obtain a mixed liquid;
step four, preparing a solution with the content of 1.5% by using purified water for sodium alginate, adding the solution into the mixed liquid obtained in the step three, and uniformly stirring to obtain an ointment, namely the biological product for slowing body skin neutralization and aging.
2. The biologic product for slowing the rate of aging by neutralization of body skin according to claim 1, wherein said biologic product comprises trypsin, pancreatic amylase, pancreatic lipase, thymosin, a plurality of biological enzymes, polypeptides, polysaccharides, lipopolysaccharides, lipoproteins.
3. The biologic product for slowing the rate of aging of body skin neutralization according to claim 1, wherein said biologic product is a cream cryopreservation product, a freeze-dried product, or other form of preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211285429.0A CN115475136A (en) | 2022-10-20 | 2022-10-20 | Biological product for slowing body skin neutralization aging rate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211285429.0A CN115475136A (en) | 2022-10-20 | 2022-10-20 | Biological product for slowing body skin neutralization aging rate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115475136A true CN115475136A (en) | 2022-12-16 |
Family
ID=84396772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211285429.0A Pending CN115475136A (en) | 2022-10-20 | 2022-10-20 | Biological product for slowing body skin neutralization aging rate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115475136A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6366124A (en) * | 1986-09-08 | 1988-03-24 | Yamakawa Boeki Kk | Production of deproteinized thymus extract having metabolic activity |
| JPS63188698A (en) * | 1987-01-29 | 1988-08-04 | Ichimaru Pharcos Co Ltd | Cell growth promoting substance extracted from bovine thymus, extraction thereof and inactivation treatment of virus |
| CN107281093A (en) * | 2017-08-28 | 2017-10-24 | 王发欣 | The method and moisturiser of moisturiser are prepared by animal pancreas |
| CN112442497A (en) * | 2019-09-04 | 2021-03-05 | 四川德博尔制药有限公司 | Preparation method of pancreatin |
-
2022
- 2022-10-20 CN CN202211285429.0A patent/CN115475136A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6366124A (en) * | 1986-09-08 | 1988-03-24 | Yamakawa Boeki Kk | Production of deproteinized thymus extract having metabolic activity |
| JPS63188698A (en) * | 1987-01-29 | 1988-08-04 | Ichimaru Pharcos Co Ltd | Cell growth promoting substance extracted from bovine thymus, extraction thereof and inactivation treatment of virus |
| CN107281093A (en) * | 2017-08-28 | 2017-10-24 | 王发欣 | The method and moisturiser of moisturiser are prepared by animal pancreas |
| CN112442497A (en) * | 2019-09-04 | 2021-03-05 | 四川德博尔制药有限公司 | Preparation method of pancreatin |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111067816A (en) | Moisturizing and repairing mask containing active polypeptide and preparation method thereof | |
| CN110051587A (en) | A kind of preparation method and application of the anti-apolexis composition containing a variety of sodium hyaluronates | |
| CN105168106B (en) | One kind three spends whitening and softening skin facial mask liquid and preparation method thereof | |
| CN107456433B (en) | Deep water replenishing preparation | |
| JP7315985B2 (en) | Soap composition using mountain ginseng and soap containing the same | |
| CN110448521A (en) | Stem Cell Activity factor facial mask sticking dressing and preparation method for skin repair | |
| KR20150039263A (en) | Cosmetic composition containing fermented herb extracts and marine derived materials | |
| CN104940109A (en) | Natural marine facial mask based on shell and preparation method of natural marine facial mask | |
| CN103385803B (en) | Preparation method of bacterial cellulose compound fish collagen protein facial mask | |
| CN114149878B (en) | Goat milk sand sagebrush mixture, preparation method and application thereof | |
| CN109010195A (en) | A kind of whitening Wrinkle-and scar-removing repairs face cream and preparation method thereof | |
| CN113101256B (en) | Anti-aging repair nanoemulsion and application thereof | |
| CN108977488B (en) | Elastin for intensive skin repair and preparation method thereof | |
| CN110368347A (en) | Anti-ageing reparation double-layer bi-color essence of one kind and preparation method thereof | |
| CN115475136A (en) | Biological product for slowing body skin neutralization aging rate | |
| JPH03236319A (en) | Skin drug for external use | |
| CN111714399B (en) | Whitening, antibacterial and cutin-removing hand sanitizer and preparation method thereof | |
| CN107898679A (en) | A kind of water light moisturizing stoste and preparation method thereof | |
| CN111714404B (en) | Acne-removing composition and preparation method and application thereof | |
| CN107982203A (en) | Neck cream containing human adipose-derived mesenchymal stem cell extract | |
| CN107961183A (en) | A kind of toxin expelling anti-inflammatory facial mask | |
| CN113244140A (en) | Composition for regulating skin micro-ecological balance and application and preparation method thereof | |
| CN113599322A (en) | A shampoo formula containing Gleditsia sinensis saponin and its preparation method | |
| CN111494279A (en) | Cleaning cosmetic and preparation method thereof | |
| CN110302125A (en) | Assign maintenance facial mask living |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |