CN115463046A - Bacteriostatic hand sanitizer easy to wash and preparation method thereof - Google Patents
Bacteriostatic hand sanitizer easy to wash and preparation method thereof Download PDFInfo
- Publication number
- CN115463046A CN115463046A CN202211010425.1A CN202211010425A CN115463046A CN 115463046 A CN115463046 A CN 115463046A CN 202211010425 A CN202211010425 A CN 202211010425A CN 115463046 A CN115463046 A CN 115463046A
- Authority
- CN
- China
- Prior art keywords
- percent
- hand sanitizer
- sodium
- bacteriostatic
- essence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses an antibacterial hand sanitizer easy to wash and a preparation method thereof. The hand sanitizer comprises the following components in percentage by mass: 4 to 10 percent of palmitoyl sodium glutamate, 4 to 8 percent of sodium lauroyl glycinate propionate, 1 to 5 percent of cocamidopropyl amine oxide, 1 to 3 percent of lauroyl isopropanolamine, 1 to 5 percent of octyl/decyl glucoside, 1 to 3 percent of undecylenoyl hydrolyzed wheat protein zinc, 2 to 5 percent of bacteriostatic agent, 1 to 5 percent of humectant, 0.01 to 0.1 percent of metal chelating agent, 0.1 to 1 percent of pH regulator, 0.01 to 0.1 percent of essence, and the balance of water. The hand sanitizer disclosed by the invention is mild in quality, low in irritation, proper in viscosity, rich in foam, easy to wash, wide in antibacterial spectrum, good in antibacterial effect on gram-negative bacteria, gram-positive bacteria and gram-positive fungi, and wide in application prospect.
Description
Technical Field
The invention belongs to the technical field of daily chemical articles, and particularly relates to an antibacterial hand sanitizer easy to wash and a preparation method thereof.
Background
The hand sanitizer is one of important daily necessities in daily life, and has various varieties and large consumption. As a primary cleaning product for personal homes and public places, hand sanitizers are closely associated with health. A high-quality antibacterial hand sanitizer has the characteristics of high safety, strong detergency, good antibacterial activity, low irritation and the like. At present, the hand sanitizer on the market is mainly divided into a soap base system and a surfactant system, wherein the soap base system has the characteristic of easy washing, but has high irritation and is easy to hurt the skin of hands, the surfactant system is an AES system which has strong cleaning and degreasing capabilities, and the hands are usually dry after being washed, so that unpleasant hand washing experience is brought to users.
The hand sanitizer of an amino acid system has mild skin effect, small irritation, low toxicity, good foaming and emulsifying properties, strong dirt-removing capacity, good biodegradability and good compatibility with other various surfactants, and is widely applied to the field of daily chemicals and used for preparing shower gel, shampoo, hand sanitizer, detergent and the like. However, the hand sanitizer with a mild amino acid surfactant system in the current market is mainly a common hand sanitizer, has no bacteriostatic function or weak bacteriostatic effect, and mainly plays a cleaning role. Therefore, the development of a novel natural, safe, efficient and bacteriostatic novel amino acid hand sanitizer with effective decontamination, environmental friendliness and low cost has important practical significance.
Disclosure of Invention
The invention aims to provide an antibacterial hand sanitizer easy to wash and a preparation method thereof. The hand sanitizer has the advantages of mild quality, low irritation, proper viscosity, abundant foam, easiness in washing, wide antibacterial spectrum and good antibacterial effect on gram negative bacteria, gram positive bacteria and gram negative bacteria and fungi.
The invention is realized by the following technical scheme:
an easy-to-wash antibacterial hand sanitizer comprises the following components in percentage by mass: 4 to 10 percent of palmitoyl sodium glutamate, 4 to 8 percent of sodium lauroyl glycinate propionate, 1 to 5 percent of cocamidopropyl amine oxide, 1 to 3 percent of lauroyl isopropanolamine, 1 to 5 percent of octyl/decyl glucoside, 1 to 3 percent of undecylenoyl hydrolyzed wheat protein zinc, 2 to 5 percent of bacteriostatic agent, 1 to 5 percent of humectant, 0.01 to 0.1 percent of metal chelating agent, 0.1 to 1 percent of pH regulator, 0.01 to 0.1 percent of essence, and the balance of water.
Preferably, the bacteriostatic hand sanitizer easy to wash comprises the following components in percentage by mass: 6 to 8 percent of palmitoyl sodium glutamate, 4 to 6 percent of sodium lauroyl glycinate propionate, 2 to 4 percent of cocamidopropyl amine oxide, 1 to 2 percent of lauroyl isopropanolamine, 2 to 4 percent of octyl/decyl glucoside, 1 to 3 percent of undecylenic hydrolyzed wheat protein zinc, 2 to 4 percent of bacteriostatic agent, 2 to 4 percent of humectant, 0.01 to 0.1 percent of metal chelating agent, 0.1 to 1 percent of pH regulator, 0.01 to 0.1 percent of essence and the balance of water.
Preferably, the bacteriostatic agent is composed of eugenol glucoside and repacketisium germanium according to the mass ratio of 1 (0.3-0.7).
Preferably, the bacteriostatic agent consists of eugenol glucoside and repaglinide in a mass ratio of 1.
Preferably, the humectant is at least one selected from propylene glycol, butylene glycol, glycerin, squalane, ceramide, jojoba oil, sodium hyaluronate and sodium tocopheryl phosphate.
Preferably, the metal chelating agent is at least one selected from sodium gluconate, pentasodium penta-pentetate, disodium ethylene diamine tetraacetate, tetrasodium ethylene diamine tetraacetate and sodium ethylene diamine tetra-methyl-methylene phosphate.
Preferably, the pH regulator is at least one selected from sodium citrate and citric acid.
Preferably, the essence is at least one selected from menthol, jasmine essence, green tea essence, grapefruit essence, sweet orange essence and osmanthus essence.
The method for preparing the bacteriostatic hand sanitizer easy to wash specifically comprises the following steps:
sequentially adding palmitoyl sodium glutamate, sodium lauroyl glycinate propionate, cocamidopropyl amine oxide, lauroyl isopropanolamine and water into a reaction kettle, uniformly stirring, heating to 60-75 ℃, keeping the temperature for 20-30 min, cooling to 50-55 ℃, adding octyl/decyl glucoside, undecylenoyl hydrolyzed wheat protein zinc, a bacteriostatic agent, a humectant, a metal chelating agent and a pH regulator, stirring for 30-60 min, continuously cooling to room temperature, adding essence, uniformly stirring, and discharging to obtain the compound.
Compared with the prior art, the invention has the following beneficial effects:
1. the washing product containing the amino acid surfactant has the common use experience of difficult thickening and unclean washing. According to the invention, by optimizing the surfactant composition of the hand sanitizer, sodium palmitoyl glutamate and sodium lauroyl glycine propionate are used as main surfactants, and cocoamidopropyl amine oxide, lauroyl isopropanolamine and undecylenic hydrolyzed wheat protein zinc are compounded as auxiliary surfactants, so that the hand sanitizer which is low in irritation, proper in viscosity, rich in foam and easy to wash is obtained, and the defects of difficult thickening and unclean washing of the existing amino acid hand sanitizer are overcome.
2. The invention takes the combination of the eugenol glucoside and the repacketia as the antibacterial agent, has the characteristics of high efficiency and wide antibacterial spectrum, can inhibit gram-negative bacteria and gram-positive bacteria, can also inhibit fungi, and effectively prevents the invasion of various pathogenic microorganisms. The eugenol glucoside is a glucoside of eugenol, has improved hydrophilic lipophilicity and bioavailability, reduced volatility and irritation, and certain inhibitory activity on bacteria and fungi. Repage, also known as dicarboxyethyl germanium sesquioxide, has a weak inhibitory activity against bacteria and fungi. The inventor finds that the inhibitory activity of the eugenol glucoside and the repacketisol germanium on bacteria and fungi is obviously improved by compounding the eugenol glucoside and the repacketisol germanium according to a certain proportion, and the synergistic inhibitory activity is generated by compounding the eugenol glucoside and the repacketisol germanium. The combination of eugenol glucoside and repacketisium can be used as a bacteriostatic agent for preparing hand sanitizer and obtain excellent bacteriostatic effect.
In a word, the antibacterial hand sanitizer provided by the invention can deeply decontaminate, has strong antibacterial power and abundant foam, is easy to flush and biodegrade, has the effects of moisturizing and moistening skin, and is simple in preparation process and easy for industrial production.
Detailed Description
The following examples are further illustrative of the present invention and are not intended to be limiting thereof. The components of the formulations in the following examples are, unless otherwise specified, conventional commercial products.
Example 1
An easy-to-wash antibacterial hand sanitizer comprises the following components in percentage by mass: 8% of palmitoyl sodium glutamate, 5% of sodium lauroyl glycine propionate, 4% of cocamidopropyl amine oxide, 2% of lauroyl isopropanolamine, 4% of octyl/decyl glucoside, 3% of undecylenoyl hydrolyzed wheat protein zinc, 2.7% of eugenol glucoside, 1.3% of repacke germanium, 2% of glycerol, 0.1% of disodium ethylene diamine tetraacetate, 0.2% of sodium citrate, 0.4% of citric acid, 0.05% of green tea essence and the balance of water.
The preparation method comprises the following steps: sequentially adding palmitoyl sodium glutamate, sodium lauroyl glycinate propionate, cocamidopropyl amine oxide, lauroyl isopropanolamine and water into a reaction kettle, uniformly stirring, heating to 70 ℃, keeping the temperature for 30min, cooling to 50 ℃, adding octyl/decyl glucoside, undecylenoyl hydrolyzed wheat protein zinc, eugenol glucoside, repage, glycerin, disodium ethylene diamine tetraacetate, sodium citrate and citric acid, stirring for 60min, continuously cooling to room temperature, adding green tea essence, uniformly stirring, and discharging to obtain the tea beverage.
Example 2
An easy-to-wash antibacterial hand sanitizer comprises the following components in percentage by mass: sodium palmitoyl glutamate 6%, sodium lauroyl glycinate propionate 6%, cocamidopropyl amine oxide 2%, lauroyl isopropanolamine 2%, octyl/decyl glucoside 4%, undecylenoyl hydrolyzed wheat protein zinc 1%, eugenol glucoside 3%, repage 1%, propylene glycol 2%, jojoba oil 2%, disodium edetate 0.01%, sodium citrate 0.4%, citric acid 0.6%, jasmine essence 0.01%, and the balance of water. Preparation procedure reference example 1 was made.
Example 3
An easy-to-wash antibacterial hand sanitizer comprises the following components in percentage by mass: 7% of palmitoyl sodium glutamate, 4% of sodium lauroyl glycine propionate, 3% of cocamidopropyl amine oxide, 1% of lauroyl isopropanolamine, 2% of octyl/decyl glucoside, 3% of undecylenoyl hydrolyzed wheat protein zinc, 2.4% of eugenol glucoside, 1.6% of repacketized germanium, 1% of butanediol, 2% of squalane, 0.05% of disodium ethylenediaminetetraacetate, 0.1% of sodium citrate, 0.4% of citric acid, 0.1% of orange essence, and the balance of water. Preparation procedure reference example 1 was made.
Example 4
An easy-to-wash antibacterial hand sanitizer comprises the following components in percentage by mass: 10% of palmitoyl sodium glutamate, 4% of sodium lauroyl glycine propionate, 5% of cocamidopropyl amine oxide, 1% of lauroyl isopropanolamine, 5% of octyl/decyl glucoside, 1% of undecylenoyl hydrolyzed wheat protein zinc, 1.3% of eugenol glucoside, 0.7% of repacke germanium, 0.5% of glycerol, 0.5% of sodium tocopheryl phosphate, 0.05% of disodium edetate, 0.1% of sodium citrate, 0.4% of citric acid, 0.1% of grapefruit essence, and the balance of water. The preparation procedure is as in example 1.
Example 5
An antibacterial hand sanitizer easy to wash comprises the following components in percentage by mass: 4% of palmitoyl sodium glutamate, 8% of sodium lauroyl glycinate propionate, 1% of cocamidopropyl amine oxide, 3% of lauroyl isopropanolamine, 1% of octyl/decyl glucoside, 3% of undecylenoyl hydrolyzed wheat protein zinc, 3.8% of eugenol glucoside, 1.2% of repacke germanium, 3% of glycerol, 2% of ceramide, 0.05% of disodium edetate, 0.1% of sodium citrate, 0.3% of citric acid, 0.1% of green tea essence and the balance of water. The preparation procedure is as in example 1.
Comparative example 1
The bacteriostatic, easy-to-rinse hand sanitizer of comparative example 1 was prepared as compared to example 1 except that eugenol glucoside was absent and the amount of repatriage was increased accordingly. The preparation procedure was as described in the examples above.
Comparative example 2
The bacteriostatic, easy-to-rinse hand sanitizer of comparative example 2 was prepared as compared to example 1 except that no repatriage was included, with a corresponding increase in eugenol glucoside. The preparation procedure was as described in the examples above.
Comparative example 3
The easy-to-rinse bacteriostatic hand sanitizer of comparative example 3 was prepared as compared to example 1, except that eugenol glucoside and repatriage were not included. The preparation procedure was as described in the examples above.
Comparative example 4
The bacteriostatic easy-to-rinse hand sanitizer of comparative example 4 was prepared as compared to example 1, except that kaempferol-7-glucoside was substituted for eugenol glucoside. The preparation procedure was as described in the examples above.
Comparative example 5
Comparative example 5 an easy-to-rinse bacteriostatic hand sanitizer was prepared as compared to example 1, except that eugenol glucoside and repapragermanium were replaced with kaempferol-7-glucoside. The preparation procedure was as described in the examples above.
Test example I, patch test on human skin
The antibacterial hand sanitizer prepared in examples 1-5 and comparative examples 1-5 of the invention is tested according to related requirements and determination methods of a human skin patch test in 2015 edition of cosmetic hygiene code issued by the ministry of health, skin reactions are observed at 0h, 6h, 12h, 24h and 48h respectively, the experimental results of all volunteer subjects are negative results, and no adverse skin reaction occurs. The antibacterial hand sanitizer provided by the invention has the advantages of no anaphylactic reaction, no irritation and high safety.
Test example two evaluation of bacteriostatic Activity
The bactericidal effect of the bacteriostatic hand sanitizer prepared in examples 1 to 5 and comparative examples 1 to 5 on staphylococcus aureus, escherichia coli, candida albicans and candida albicans is determined by referring to a sterilization method in appendix C of 15979-2002 hygienic Standard for Disposable sanitary articles, and the calculated bacteriostatic rate (%) is shown in table 1.
TABLE 1 results of the test of the bacteriostatic activity
The results show that the antibacterial hand sanitizer prepared in the examples 1-5 has good antibacterial effect on staphylococcus aureus, escherichia coli, candida albicans and candida, and the antibacterial rate is up to more than 99.0%, which is superior to that of the hand sanitizer in the comparative examples 1-5. As can be seen from comparative examples 1-3, eugenol glucoside has certain inhibitory activity on bacteria and fungi, repa germanium has weaker inhibitory activity on bacteria and fungi, and the inhibitory activity on the bacteria and the fungi is obviously improved by compounding eugenol glucoside and the repa germanium according to a certain proportion, and the synergistic inhibitory activity is generated by compounding the eugenol glucoside and the repa germanium. As shown in comparative examples 4-5, kaempferol-7-glucoside and repatriage cannot generate obvious synergistic bacteriostatic effect when used together.
Test example III evaluation of foaming Properties
And (3) adding 0.5mL of prepared sample and 20mL of distilled water into a test tube, plugging the opening of the test tube by using a thumb to ensure that the direction strength tends to be consistent, shaking for 30 times, adding 20mL of distilled water along the tube wall, and flushing the foam on the tube wall. Two values need to be recorded, the first is the stable height of the foam which does not drop after shaking, the height is used for measuring the foaming performance of the hand sanitizer, and the second is the time consumed by destroying the foam to half of the original height after adding the clean water slowly, and is used for representing whether the generated foam is stable or not. The procedure was repeated three times and data and average values for each group were recorded and the results are shown in table 2.
TABLE 2 evaluation results of foaming Properties
Group of | Foam height/mm | Time/s for foam to collapse to half of original height |
Example 1 | 135 | 37 |
Example 2 | 127 | 31 |
Example 3 | 129 | 33 |
Example 4 | 134 | 36 |
Example 5 | 130 | 34 |
According to the requirements of national standards, the height of the foam is more than or equal to 100mm, the time for the foam to be damaged to half of the original height is more than 25s, and the test liquid soap meets the requirements, so that the finished liquid soap is proved to have good foam performance. As shown in Table 2, the bacteriostatic hand sanitizer prepared in the embodiments 1 to 5 of the present invention has good foaming and foam stabilizing properties.
Test example four evaluation of Using effects
Screening 100 volunteers, dividing the volunteers into an example 1-5 group and a comparative example 1-5 group, carrying out sensory evaluation on 10 persons in each group by correspondingly using the hand sanitizer prepared in the examples 1-5 and the comparative examples 1-5 of the invention, carrying out the evaluation on 10 points with the highest point of 10 points and the lowest point of 0 point, averaging the points scored by all the volunteers, and counting the performance evaluation results of the volunteers on the product, wherein the results are shown in a table 3.
TABLE 3 evaluation results of Using effects
The results show that the hand sanitizer prepared in the examples 1-5 has abundant foam, is easy to wash, has strong detergency, low irritation and good moisturizing property, and the total using effect score is better than that of the hand sanitizer prepared in the comparative examples 1-5.
The above is only a preferred embodiment of the present invention, and it should be noted that the above preferred embodiment should not be considered as limiting the present invention, and the protection scope of the present invention should be subject to the scope defined by the claims. It will be apparent to those skilled in the art that various modifications and adaptations can be made without departing from the spirit and scope of the invention, and these modifications and adaptations should be considered within the scope of the invention.
Claims (9)
1. An antibacterial hand sanitizer easy to wash is characterized by comprising the following components in percentage by mass: 4 to 10 percent of palmitoyl sodium glutamate, 4 to 8 percent of sodium lauroyl glycinate propionate, 1 to 5 percent of cocamidopropyl amine oxide, 1 to 3 percent of lauroyl isopropanolamine, 1 to 5 percent of octyl/decyl glucoside, 1 to 3 percent of undecylenic hydrolyzed wheat protein zinc, 2 to 5 percent of bacteriostatic agent, 1 to 5 percent of humectant, 0.01 to 0.1 percent of metal chelating agent, 0.1 to 1 percent of pH regulator, 0.01 to 0.1 percent of essence and the balance of water.
2. The bacteriostatic hand sanitizer easy to rinse according to claim 1, which is characterized by comprising the following components in percentage by mass: 6 to 8 percent of palmitoyl sodium glutamate, 4 to 6 percent of sodium lauroyl glycinate propionate, 2 to 4 percent of cocamidopropyl amine oxide, 1 to 2 percent of lauroyl isopropanolamine, 2 to 4 percent of octyl/decyl glucoside, 1 to 3 percent of undecylenoyl hydrolyzed wheat protein zinc, 2 to 4 percent of bacteriostatic agent, 2 to 4 percent of humectant, 0.01 to 0.1 percent of metal chelating agent, 0.1 to 1 percent of pH regulator, 0.01 to 0.1 percent of essence, and the balance of water.
3. The bacteriostatic hand sanitizer easy to wash of claim 1 or 2, wherein the bacteriostatic agent is composed of eugenol glucoside and repacketisol germanium in a mass ratio of 1 (0.3-0.7).
4. The bacteriostatic hand sanitizer easy to wash of claim 3, wherein the bacteriostatic agent is eugenol glucoside and repackethrin in a mass ratio of 1.
5. An easily washable bacteriostatic hand sanitizer according to claim 1 or 2, wherein said humectant is selected from at least one of propylene glycol, butylene glycol, glycerin, squalane, ceramide, jojoba oil, sodium hyaluronate, and sodium tocopheryl phosphate.
6. An easily washable bacteriostatic hand sanitizer according to claim 1 or 2, wherein said metal chelating agent is at least one selected from the group consisting of sodium gluconate, pentasodium penta-pentetate, disodium edetate, tetrasodium edetate and sodium edetate.
7. An easily washable bacteriostatic hand sanitizer according to claim 1 or 2, wherein said pH regulator is at least one selected from sodium citrate and citric acid.
8. An easily washable bacteriostatic hand sanitizer according to claim 1 or 2, wherein said essence is at least one selected from menthol, jasmine essence, green tea essence, grapefruit essence, sweet orange essence and osmanthus essence.
9. A method of preparing a hand sanitizer according to any of claims 1 to 8, comprising the steps of: sequentially adding sodium palmitoyl glutamate, sodium lauroyl glycinate propionate, cocamidopropyl amine oxide, lauroyl isopropanolamine and water into a reaction kettle, uniformly stirring, heating to 60-75 ℃, keeping the temperature for 20-30 min, cooling to 50-55 ℃, adding octyl/decyl glucoside, undecylenoyl hydrolyzed wheat protein zinc, a bacteriostatic agent, a humectant, a metal chelating agent and a pH regulator, stirring for 30-60 min, continuously cooling to room temperature, adding essence, uniformly stirring, and discharging to obtain the compound.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211010425.1A CN115463046A (en) | 2022-08-23 | 2022-08-23 | Bacteriostatic hand sanitizer easy to wash and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211010425.1A CN115463046A (en) | 2022-08-23 | 2022-08-23 | Bacteriostatic hand sanitizer easy to wash and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN115463046A true CN115463046A (en) | 2022-12-13 |
Family
ID=84366620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211010425.1A Withdrawn CN115463046A (en) | 2022-08-23 | 2022-08-23 | Bacteriostatic hand sanitizer easy to wash and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN115463046A (en) |
-
2022
- 2022-08-23 CN CN202211010425.1A patent/CN115463046A/en not_active Withdrawn
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2016329881B2 (en) | Personal cleansing compositions and methods of stabilizing the microbiome | |
CN101766543B (en) | Hand sanitizer containing chlorine dioxide | |
RU2717335C1 (en) | Liquid cleaning compositions with antibacterial system and method for production thereof | |
JPH06506938A (en) | Antibacterial mild liquid skin cleanser | |
WO1997048377A1 (en) | Skin wash compositions comprising triclocarban and surfactants | |
MX2014012511A (en) | Foaming formulations including silicone polyesters. | |
CN104797234B (en) | Mild antibiotic cleaning compositions | |
CN108125812B (en) | A kind of antibacterial foam liquid soap of amino acid pattern and preparation method thereof | |
CN107468545B (en) | Green antibacterial skin-care hand sanitizer and preparation method thereof | |
CN115463046A (en) | Bacteriostatic hand sanitizer easy to wash and preparation method thereof | |
JPH11502233A (en) | Fungicide composition | |
CN111228177B (en) | Bacteriostatic easy-to-wash foam hand sanitizer and preparation method thereof | |
JPH02273617A (en) | Skin detergent composition | |
KR102247527B1 (en) | detergent using a kaffir lime | |
CN107468534A (en) | Moistening bath | |
JP2002293704A (en) | Sterilizing disinfection composition, hair shampooing composition and dish washing composition | |
CN112716820A (en) | Antibacterial skin-care lotion and preparation method thereof | |
CN112791026B (en) | Antibacterial hand sanitizer and preparation method thereof | |
JP3920129B2 (en) | Cleaning composition | |
JP3442565B2 (en) | Detergent composition | |
JP2022133728A (en) | Skin detergent composition | |
JP2003160450A (en) | Shampoo composition | |
JP3157524B2 (en) | Fungicide composition | |
EP4335432A1 (en) | Oral care cleaning sheet, and preparation method and use method therefor | |
CN115448974A (en) | Surfactant and application thereof in daily chemical products |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20221213 |
|
WW01 | Invention patent application withdrawn after publication |