JP2003160450A - Shampoo composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a shampoo composition capable of exhibiting persistent and ultrahigh fungicidal effects and having excellent effects on prevention of dandruff and pruritus of the scalp, low irritation, high safety and good usability by regulating the kind and formulation ratio of a surfactant without containing a fungicide. <P>SOLUTION: This shampoo composition is obtained by including (a) an anionic surfactant and (b) an alkylaminoacetic acid betaine surfactant in a specific formulation ratop in combination. Furthermore, the formulation ratio is preferably (1/9) to (2/1), more preferably (1/9) to (1/1) expressed in terms of weight ratio. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a shampoo composition characterized by containing no germicide. More specifically, by adjusting the type and mixing ratio of the surfactant,
It has a long-lasting and extremely high bactericidal effect, and dandruff of the scalp,
It is highly effective in preventing itching, has low irritation and high safety,
It relates to a shampoo composition having good usability.

[0002]

2. Description of the Related Art Dander and itching of the scalp are caused by the fact that the sebum and the like are decomposed by bacteria present in the scalp to form decomposed products and metabolites, and the decomposed products and metabolites stimulate the scalp. To do. Therefore, the growth of the above-mentioned bacteria is prevented, the decomposition products and metabolites of sebum are reduced, and dandruff of the scalp,
In order to suppress itching, many cosmetics for hair containing a bactericide and an antibacterial agent have been studied.

However, when a shampoo composition is blended with a bactericide, the bactericide itself is washed away from the hair by washing and does not remain sufficiently, and it is almost effective against bacteria that adhere to the hair after washing. There was a problem not to do.

In addition, since many of these bactericidal and antibacterial agents are irritating to the skin or mucous membranes and have side effects such as causing allergic disorders and the like, there are many cases of safety problems. At present, the effect cannot be fully exerted due to the limitation of the amount used and the dosage form that can be compounded.

On the other hand, among the surfactants which are essential components for shampoo compositions, many studies have been made to use those having a bactericidal effect as a cleaning base. It is generally known that cationic surfactants, alkylaminoacetic acid betaine-type surfactants, which are a type of amphoteric surfactants, etc., have a bactericidal effect.

In particular, the alkylaminoacetic acid betaine type surfactant is a useful raw material which is widely used in detergent compositions such as shampoo compositions as a base having both a bactericidal effect and a surfactant activity. is there. These alkylaminoacetic acid betaine-type surfactants have insufficient detergency and foaming power to be used alone, so from the viewpoint of usability, they should be used in combination with anionic surfactants that are excellent in detergency and foaming power. Used. It is known that the combined use of these surfactants synergistically improves the feeling of use.

However, when such an alkylaminoacetic acid betaine type surfactant is blended with a detergent containing an anionic surfactant as a main base, these surfactants form a complex with each other. However, there is a problem that the bactericidal effect of the alkylaminoacetic acid betaine type surfactant is not sufficiently exhibited.

[0008] In recent years, in order to obtain a composition mild to the skin, a weakly acidic detergent having a pH close to the surface of the skin tends to be preferred, but the detergent composition makes the system weakly acidic. In that case, there is a weakness that it is difficult to maintain sufficient antibacterial property even if a bactericide is added.

Therefore, it is possible to obtain a shampoo composition which has a high bactericidal effect, an excellent effect of preventing dandruff and itchiness of the scalp, low irritation, high safety, good usability, and which can sufficiently satisfy consumers. It wasn't easy.

[0010]

Therefore, in the present invention, the kind of the surfactant,
By adjusting the blending ratio, it exerts a sustained and extremely high bactericidal effect, and has an excellent effect of preventing scalp dandruff and itching.
It was intended to obtain a shampoo composition having low irritation, high safety and good usability.

[0011]

[Means for Solving the Problems] As a result of intensive studies to solve the above problems, as a result, an anionic surfactant and an alkylaminoacetic acid betaine-type surfactant are used in combination and contained at a specific mixing ratio. Exhibits a sustained and extremely high bactericidal effect, has an excellent effect of preventing dandruff and itching of the scalp, has low irritation, high safety and good usability,
It was found that a shampoo composition can be obtained, and the present invention has been completed.

That is, the present invention relates to a shampoo composition comprising an anionic surfactant and an alkylaminoacetic acid betaine type surfactant in a specific compounding ratio.

[0013]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described in detail below.

As the anionic surfactant used in the present invention, polyoxyethylene alkyl ether sulfate, alkyl sulfate ester, α-olefin sulfonate,
Examples thereof include alkylbenzene sulfonate, higher fatty acid soap, alkyl ether phosphate salt, acyl amino acid salt, and the like, and it is particularly preferable to use polyoxyethylene alkyl ether sulfate.

The amount of the anionic surfactant blended is preferably about 0.1 to 10% by weight, more preferably 0.2 to 5% by weight, based on the entire shampoo composition.

Examples of the alkylaminoacetic acid betaine type surfactants used in the present invention include N-lauryldimethylaminoacetic acid betaine, N-myristyldimethylaminoacetic acid betaine and N-stearyldimethylaminoacetic acid betaine.

The amount of the betaine alkylaminoacetate surfactant is 0.1 to 0.1% with respect to the total shampoo composition.
It is preferably about 20% by weight, more preferably 5 to 15% by weight.

An anionic surfactant used in the present invention,
The blending ratio of the alkylaminoacetic acid betaine type surfactant in the shampoo composition is preferably 1/9 to 2/1 by weight, and more preferably 1/9 to 1/1. . If the ratio is out of the range, the sterilizing power and the feeling of use may decrease.

Further, the shampoo composition of the present invention may contain a cationic polymer compound. Examples of such a composition include dimethyldiallylammonium chloride / acrylic acid copolymer, vinylpyrrolidone / N, N
-Dimethylaminoethyl methacrylic acid copolymer diethyl sulfate solution, vinyl acetate / vinylpyrrolidone copolymer, O- [2-hydroxy-3- (trimethylammonio) propyl] hydroxyethyl cellulose chloride, O-chloride
[2-hydroxy-3- (trimethylammonio) propyl] guar gum and the like can be mentioned.

The amount of the above cationic polymer compound is preferably about 0.01 to 5% by weight, more preferably 0.05 to 3% by weight, based on the entire shampoo composition.

The addition of the above cationic polymer compound did not impair the bactericidal effect, and it was confirmed that the usability such as the feel at the time of washing off was improved.

The shampoo composition of the present invention may further contain other components as long as the effects of the present invention are not impaired. Examples of such components include amphoteric surfactants other than the above, nonionic surfactants, cationic surfactants, plant extracts, vitamins, alcohols, polyols, oils, pearlizing agents, moisturizing ingredients, fragrances, dyes, and ultraviolet rays. Absorption agents, antioxidants, anti-inflammatory agents and the like can be mentioned.

Further, for the purpose of further enhancing the bactericidal and antibacterial effects of the shampoo composition, for example, paraoxybenzoic acid esters such as methyl paraoxybenzoate, methyl sodium paraoxybenzoate, benzoic acid, sodium benzoate, phenoxyethanol, gluconic acid. Chlorohexidine, lysozyme chloride, sorbate, dihydroacetate,
Benzethonium chloride, isopropylmethylphenol,
Photosensitizer, cetylpyridinium chloride, piroctone olamine, zinc pyrithione, 2,2,4-trichloro-2 '
-Hydroxydiphenyl ether, triclocarban,
Preservatives such as triclosan and benzalkonium chloride, and bactericides can also be added.

[0024]

EXAMPLES The present invention will be described in more detail by showing examples, but the technical scope of the present invention is not limited thereby. Unless otherwise specified, the unit weights in the examples are shown by weight%.

Example 1 (1) Sodium polyoxyethylene lauryl sulfate 2.50 (2) Betaine N-myristyldimethylaminoacetate 12.00 (3) Betaine N-lauryldimethylaminoacetate 1.75 (4) Dimethyldiallyl chloride Ammonium / acrylic acid copolymer liquid (37.5% aqueous solution) 0.50 (5) Coconut oil fatty acid diethanolamide 1.20 (6) Dipotassium glycyrrhizinate 0.10 (7) DL-α-tocopherol 2-L- Ascorbic acid phosphoric acid diester potassium salt 0.05 (8) Citric acid pH amount of 5.0 (9) Purified water amount of 100 Total production method: (1) to (8) are sequentially added to (9). And mix and dissolve evenly.

Example 2 (1) N-coconut oil fatty acid methyl taurine sodium 2.6 (2) Polyoxyethylene (3EO) alkyl (C12-C15) sodium ether sulfate 2.4 (3) N-myristyl Dimethylaminoacetic acid betaine 5.0 (4) Coconut oil fatty acid diethanolamide 4.0 (5) Citric acid Amount to make pH 5.5 (6) O- [2-hydroxy-3- (trimethylammonio) propyl chloride chloride ] Guar gum 0.5 (7) Hydrolyzed collagen powder 0.2 (8) Fragrance 0.1 (9) Purified water Amount with 100 as the total amount Manufacturing method: (1) to (8) are sequentially added to (9) Mix evenly and dissolve.

In Example 1, betaine N-myristyldimethylaminoacetate and betaine N-lauryldimethylaminoacetate were all replaced by sodium polyoxyethylene lauryl sulfate, and in Example 2, N-myristyldimethylaminoacetate was used. All betaine acetate N-
Substitutes for coconut oil fatty acid methyl taurine sodium were prepared and designated as Comparative Example 1 and Comparative Example 2.

Next, for each of the above Examples and Comparative Examples, dandruff fungus (Malassezia furfa, Malassezia f
The bactericidal effect on urfur ) was evaluated by the following method.

For 20 g of sample, dandruff bacteria 1.0 × 10 ⁴
(Cfu / mL) was inoculated and thoroughly stirred. 10
After leaving it for a minute, it was diluted 10-fold and smeared on a PDA medium.
This was cultured at 37 ° C. for 4 days, the viable cell count was measured, and the survival rate was calculated.

As a result, the survival rate of dandruff was 1.9% in Example 1 and 10% in Example 2, showing that it has a sufficient bactericidal effect. On the other hand, the dandruff survival rate in Comparative Example 1 was 114% and that in Comparative Example 2 was 103%, and the shampoo composition containing no alkylaminoacetic acid betaine-type surfactant has a sufficient bactericidal effect. I didn't.

Antidandruff Evaluation and Itch Inhibition Evaluation Using the shampoo compositions of each Example and Comparative Example, 20 adult men and women with dandruff and itching associated with dandruff were used as a group and usually used daily before bedtime. A proper amount of shampoo was used instead of the shampoo, and a continuous use test for suppressing dandruff and itch was carried out for 2 months. The evaluation criteria are as defined below, and the results are shown in Table 1 by the number of people who answered each evaluation.

[Antidancer effect] Effective: Suppressed dandruff Slightly effective: Slightly suppressed dandruff Invalid: No change from before use "Itching control effect" Effective: Itching improved Slightly effective: Itching slightly improved Invalid: No change from before use

[0033]

[Table 1]

As shown in Table 1, as a result of the dandruff suppression evaluation, the panelists who answered "effective" in Examples 1 and 2 of the present invention were 85% and 75%, respectively, and the results of the itch suppression evaluation were the results of the present invention. The panelists who answered “effective” in Example 1 and Example 2 were 80% and 85%, respectively, showing suppression of dandruff and improvement of itch, and very good results were obtained even compared with the comparative example. Was given.

Evaluation of Skin Irritation / Ocular Mucosa Irritation The skin irritation was evaluated by a 48-hour back-occlusion patch test conducted by 30 male panelists using a 1.0% by weight aqueous solution of each Example as a sample. Points were scored according to the criteria shown, and the average value of 30 persons was calculated. Regarding eye mucous membrane irritation, 20 male and female panelists
An actual use (washing) test was conducted as a group, and the irritation that the eyes felt during use, such as bleeding on the eyes, was evaluated according to the evaluation criteria shown in Table 3 and scored, and the average value of 20 people was obtained. The results are shown in Table 4.

[0036]

[Table 2]

[0037]

[Table 3]

[0038]

[Table 4]

As shown in Table 4, the results of the skin irritation evaluation and the eye mucous membrane irritation evaluation showed almost no skin irritation.
Furthermore, almost no irritation of the eye mucous membrane was felt.

No panelists complained about the feeling of use of the shampoo composition of each Example.

Example 3 (1) Sodium polyoxyethylene lauryl sulfate 2.50 (2) Betaine N-myristyldimethylaminoacetate 12.00 (3) Betaine N-lauryldimethylaminoacetate 1.75 (4) Dimethyldiallyl chloride Ammonium / acrylic acid copolymer solution (37.5% aqueous solution) 0.50 (5) Coconut oil fatty acid diethanolamide 1.50 (6) Dipotassium glycyrrhizinate 0.10 (7) DL-α-tocopherol 2-L- Ascorbic acid phosphoric acid diester potassium salt 0.05 (8) Sodium chloride 2.00 (9) Sodium hydrogen carbonate 0.08 (10) Citric acid 0.08 (11) Salicylic acid 0.20 (12) Piroctone olamine 0 .30 (13) Purified water 78.94 Manufacturing method: (1) to (12) are sequentially (13). Uniformly mixed was added and dissolved.

[0042]

[Effects of the Invention] An anionic surfactant and an alkylaminoacetic acid betaine-type surfactant are used in combination, and by containing them in a specific compounding ratio, a sustained and extremely high bactericidal effect is exerted, and scalp dander, Excellent in preventing itching,
It was possible to obtain a shampoo composition with low irritation, high safety and good usability.

Continued front page    F-term (reference) 4C083 AB332 AC302 AC472 AC642                       AC692 AC711 AC712 AC782                       AC792 AC852 AD132 AD432                       AD532 AD662 BB05 BB51                       BB53 CC38 DD23 EE10 EE12                 4H003 AB23 AB31 AC13 AD04 BA12                       DA02 EB07 EB08 EB23 EB30                       EB44 EB46 ED02 FA02 FA26                       FA34

Claims (4)

[Claims] 1. (a) an anionic surfactant, and (b)
Contains an alkylaminoacetic acid betaine-type surfactant,
A shampoo composition, wherein the weight ratio of (a) and (b) is 1/9 to 2/1. 2. No bactericide is contained,
The shampoo composition according to claim 1. 3. The shampoo composition according to claim 1 or 2, which is used for anti-dandruff and anti-itch. 4. Shampoo composition according to claims 1 to 3, characterized in that it is weakly acidic.