CN115461064A - 针对移植物抗宿主病的预防或治疗用组合物 - Google Patents

针对移植物抗宿主病的预防或治疗用组合物 Download PDF

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Publication number
CN115461064A
CN115461064A CN202080082543.6A CN202080082543A CN115461064A CN 115461064 A CN115461064 A CN 115461064A CN 202080082543 A CN202080082543 A CN 202080082543A CN 115461064 A CN115461064 A CN 115461064A
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dna
bacteroides
bacteria
unclassified
genus
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Pending
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CN202080082543.6A
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English (en)
Chinese (zh)
Inventor
垣花和彦
稻本恭子
本田贤也
竹下梢
切通优子
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Keio School
Tokyo Metropolitan Hospital Institution A Local Independent Administrative Legal Entity
JSR Corp
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Keio School
Floating Kyoto
JSR Corp
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Application filed by Keio School, Floating Kyoto, JSR Corp filed Critical Keio School
Publication of CN115461064A publication Critical patent/CN115461064A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202080082543.6A 2019-11-26 2020-11-25 针对移植物抗宿主病的预防或治疗用组合物 Pending CN115461064A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019-213436 2019-11-26
JP2019213436 2019-11-26
PCT/JP2020/043883 WO2021106952A1 (ja) 2019-11-26 2020-11-25 移植片対宿主病に対する予防又は治療用組成物

Publications (1)

Publication Number Publication Date
CN115461064A true CN115461064A (zh) 2022-12-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080082543.6A Pending CN115461064A (zh) 2019-11-26 2020-11-25 针对移植物抗宿主病的预防或治疗用组合物

Country Status (5)

Country Link
US (2) US20230024068A1 (enExample)
EP (1) EP4085916A4 (enExample)
JP (1) JPWO2021106952A1 (enExample)
CN (1) CN115461064A (enExample)
WO (1) WO2021106952A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118987051A (zh) * 2024-09-13 2024-11-22 南方医科大学南方医院 粪副拟杆菌在制备治疗移植物抗宿主病药物中的应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7783588B2 (ja) * 2021-07-21 2025-12-10 国立大学法人東海国立大学機構 腸内細菌叢に占めるコリンセラ属の情報を提供する方法、当該情報を用いたｃｏｖｉｄ－１９重症化予測方法およびサイトカインストーム重症化予測方法
US20240415900A1 (en) * 2021-10-20 2024-12-19 City Of Hope Clostridium butyricum compositions and methods of using the same
WO2025104216A1 (en) * 2023-11-15 2025-05-22 Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Bacteriophage compositions
JP2025174745A (ja) * 2024-05-17 2025-11-28 株式会社バイオパレット 人工腸内細菌叢の製造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160235792A1 (en) * 2014-11-25 2016-08-18 Epiva Biosciences, Inc. Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
US20170258854A1 (en) * 2014-11-25 2017-09-14 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
US20180185421A1 (en) * 2016-08-29 2018-07-05 Tokyo Metropolitan Government Composition comprising fecal microbiota

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61282440A (ja) 1985-06-07 1986-12-12 マルチ−テツクス　プロダクツ　コ−ポレ−シヨン 複合糸製品
NZ618935A (en) 2010-08-04 2014-03-28 Karma Medical Prod Co Ltd Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
US20150297642A1 (en) 2012-11-26 2015-10-22 Thomas Julius Borody Compositions for the restoration of a fecal microbiota and methods for making and using them
CN110191946A (zh) * 2016-12-23 2019-08-30 学校法人庆应义塾 诱导cd8+t细胞的组合物及方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160235792A1 (en) * 2014-11-25 2016-08-18 Epiva Biosciences, Inc. Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
US20170258854A1 (en) * 2014-11-25 2017-09-14 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
CN107249609A (zh) * 2014-11-25 2017-10-13 纪念斯隆-凯特琳癌症中心 肠道微生物群和gvhd
US20180185421A1 (en) * 2016-08-29 2018-07-05 Tokyo Metropolitan Government Composition comprising fecal microbiota

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SATOSHI KAITO等: "Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease", 《BLOOD ADV.》, vol. 2, no. 22, 27 November 2018 (2018-11-27), pages 3097 - 3101 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118987051A (zh) * 2024-09-13 2024-11-22 南方医科大学南方医院 粪副拟杆菌在制备治疗移植物抗宿主病药物中的应用

Also Published As

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US20250281549A1 (en) 2025-09-11
JPWO2021106952A1 (enExample) 2021-06-03
EP4085916A4 (en) 2024-03-27
US20230024068A1 (en) 2023-01-26
WO2021106952A1 (ja) 2021-06-03
EP4085916A1 (en) 2022-11-09

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Applicant after: JSR Corp.

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