CN115362270A - Egfr/her2酪氨酸激酶抑制剂和/或her2/her3抗体在具有nrg1融合的癌症的治疗中的用途 - Google Patents

Egfr/her2酪氨酸激酶抑制剂和/或her2/her3抗体在具有nrg1融合的癌症的治疗中的用途 Download PDF

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CN115362270A
CN115362270A CN202180026311.3A CN202180026311A CN115362270A CN 115362270 A CN115362270 A CN 115362270A CN 202180026311 A CN202180026311 A CN 202180026311A CN 115362270 A CN115362270 A CN 115362270A
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cancer
nrg1
fusion
patient
therapy
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J·海马赫
J·罗比肖
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University of Texas System
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University of Texas System
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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CN202180026311.3A 2020-01-29 2021-01-29 Egfr/her2酪氨酸激酶抑制剂和/或her2/her3抗体在具有nrg1融合的癌症的治疗中的用途 Pending CN115362270A (zh)

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US202062967275P 2020-01-29 2020-01-29
US62/967,275 2020-01-29
PCT/US2021/015662 WO2021155113A1 (en) 2020-01-29 2021-01-29 Use of egfr/her2 tyrosine kinase inhibitors and/or her2/her3 antibodies for the treatment of cancers with nrg1 fusions

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CN115362270A true CN115362270A (zh) 2022-11-18

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US (1) US20230112470A1 (https=)
EP (1) EP4097261A4 (https=)
JP (2) JP2023513006A (https=)
KR (1) KR20220132555A (https=)
CN (1) CN115362270A (https=)
CA (1) CA3166133A1 (https=)
WO (1) WO2021155113A1 (https=)

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JP2024523001A (ja) * 2021-06-03 2024-06-25 メルス ナムローゼ フェンノートシャップ 新たなｎｒｇ１融合体、融合接合部及びそれらを検出するための方法

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EP4097261A4 (en) 2023-10-18
US20230112470A1 (en) 2023-04-13
JP2023513006A (ja) 2023-03-30
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