CN115315445A - 一种靶向人cd47的单域抗体及其用途 - Google Patents

一种靶向人cd47的单域抗体及其用途 Download PDF

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CN115315445A
CN115315445A CN202180014200.0A CN202180014200A CN115315445A CN 115315445 A CN115315445 A CN 115315445A CN 202180014200 A CN202180014200 A CN 202180014200A CN 115315445 A CN115315445 A CN 115315445A
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antibody
seq
single domain
domain antibody
antibodies
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CN115315445B (zh
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何向宇
粘伟红
许传营
郑欣桐
张新敏
肖婧
何峰
周清
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Shanghai Shijian Biotechnology Co ltd
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Abstract

本发明涉及一种抗CD47单域抗体及其用途，以及制备该抗体的方法。所述单域抗体包含选自如下的CDR：(1)如SEQ ID NO:1、SEQ ID NO:2、SEQ ID NO:3所示的CDR1、CDR2和CDR3；或(2)如SEQ ID NO:6、SEQ ID NO:7、SEQ ID NO:8所示的CDR1、CDR2和CDR3。

Description

PCT国内申请，说明书已公开。

Claims (27)

  1. PCT国内申请，权利要求书已公开。
CN202180014200.0A 2020-02-12 2021-02-10 一种靶向人cd47的单域抗体及其用途 Active CN115315445B (zh)

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CN2020100889904 2020-02-12
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PCT/CN2021/076479 WO2021160153A1 (zh) 2020-02-12 2021-02-10 一种靶向人cd47的单域抗体及其用途

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WO2024146553A1 (en) * 2023-01-04 2024-07-11 Wuxi Biologics (Shanghai) Co., Ltd. Antibodies against cd47, method for preparing the same, and use thereof

Citations (2)

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Publication number Priority date Publication date Assignee Title
CN110003335A (zh) * 2019-04-12 2019-07-12 深圳普瑞金生物药业有限公司 Cd47单域抗体的vhh链、cd47单域抗体、核苷酸序列及试剂盒
CN110144009A (zh) * 2018-02-14 2019-08-20 上海洛启生物医药技术有限公司 Cd47单域抗体及其用途

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Publication number Priority date Publication date Assignee Title
US6075181A (en) 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
CN104804093A (zh) * 2015-05-27 2015-07-29 江苏春申堂药业有限公司 一种针对cd47的单域抗体
CN109096395B (zh) * 2017-06-20 2022-06-24 华兰生物工程股份有限公司 阻断型cd47纳米抗体及其用途
EA039662B1 (ru) * 2017-10-03 2022-02-24 Закрытое Акционерное Общество "Биокад" Антитела, специфичные к cd47 и pd-l1
EP3823653A4 (en) * 2018-07-20 2022-05-18 The Trustees of Columbia University in the City of New York PROGRAMMABLE BACTERIA FOR THE TREATMENT OF CANCER

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110144009A (zh) * 2018-02-14 2019-08-20 上海洛启生物医药技术有限公司 Cd47单域抗体及其用途
CN110003335A (zh) * 2019-04-12 2019-07-12 深圳普瑞金生物药业有限公司 Cd47单域抗体的vhh链、cd47单域抗体、核苷酸序列及试剂盒

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KR20220140787A (ko) 2022-10-18
US20230086530A1 (en) 2023-03-23
JP2023516560A (ja) 2023-04-20
EP4105234A1 (en) 2022-12-21
JP7473248B2 (ja) 2024-04-23
AU2021221001A1 (en) 2022-10-06
WO2021160153A1 (zh) 2021-08-19
CN115315445B (zh) 2024-07-12
CA3167352A1 (en) 2021-08-19

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