CN115300436A - Bletilla striata composition with antibacterial and skin care functions and preparation method thereof - Google Patents
Bletilla striata composition with antibacterial and skin care functions and preparation method thereof Download PDFInfo
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- CN115300436A CN115300436A CN202210591646.6A CN202210591646A CN115300436A CN 115300436 A CN115300436 A CN 115300436A CN 202210591646 A CN202210591646 A CN 202210591646A CN 115300436 A CN115300436 A CN 115300436A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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Abstract
The invention relates to the technical field of skin care pharmacy, and discloses a bletilla striata composition with antibacterial and skin care functions and a preparation method thereof, wherein the bletilla striata composition comprises the following main components: 1-10g of bletilla striata, 1-10g of fructus forsythiae, 1-10g of radix sophorae flavescentis, 1-10g of peony root bark and 1-10g of radix scutellariae, wherein the main components are in a ratio of 2. The bletilla striata composition with the antibacterial skin care function and the preparation method thereof are characterized in that forsythia suspense, sophora flavescens, peony root bark and scutellaria baicalensis in main components are mixed, pulverized and subjected to alcohol extraction, the mixture is compressed into thick paste in vacuum, then the rhizoma bletillae is pulverized and subjected to ultrasonic extraction, the extracting solution of the rhizoma bletillae is prepared into a yellow-brown extract by using a membrane concentration technology, and finally the yellow-brown extract is mixed with cosolvents such as purified water, butanediol, pentanediol and the like to prepare a functional stock solution, so that the prepared stock solution can perform a certain protection effect on skin when the antibacterial treatment is performed on the skin.
Description
Technical Field
The invention relates to the technical field of skin care pharmacy, in particular to a bletilla striata composition with antibacterial and skin care functions and a preparation method thereof.
Background
In the prior art, the research on the field of skin disease medicines is increasing, and skin care medicines and skin disease medicines have become combined research fields, so that the skin can be nursed or treated, and meanwhile, certain diseases appearing on the skin epidermis or the smooth and elastic effects of the skin can be treated or nursed.
However, the skin surface of a human body still has more bacteria which need to be treated, so that other damages to the skin are avoided, and the existing drug therapy does not have the function of skin care while inhibiting the bacteria, so that certain damages to the skin can be caused after the therapy.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides the bletilla striata composition with the antibacterial and skin care functions and the preparation method thereof, and the bletilla striata composition has the advantages of being capable of protecting the skin to a certain extent when the skin is subjected to antibacterial treatment and the like, and solves the technical problems.
Technical scheme
In order to achieve the purpose, the invention provides the following technical scheme: a bletilla striata composition with antibacterial and skin care functions comprises the following main components: 1-10g of bletilla, 1-10g of fructus forsythiae, 1-10g of radix sophorae flavescentis, 1-10g of peony root bark and 1-10g of radix scutellariae, wherein the main components have the following proportion of 2.
Preferably, 1-10g of bletilla striata, 1-10g of fructus forsythiae, 1-10g of radix sophorae flavescentis, 1-10g of peony root bark and 1-10g of radix scutellariae, wherein the main components are in a ratio of 1.
Preferably, 1-10g of bletilla striata, 1-10g of fructus forsythiae, 1-10g of radix sophorae flavescentis, 1-10g of peony root bark and 1-10g of radix scutellariae, wherein the main components have the following ratio of 2.
Preferably, the bletilla striata composition with bacteriostatic and skin care functions and the preparation method thereof comprise the following steps:
i: the main components comprise 2;
II: vacuum compressing the extractive solution to obtain soft extract with relative density of 1.32-1.38 (60) ° C;
III: pulverizing rhizoma Bletillae into powder, adding into hot water solvent, and extracting for 2-3 times by ultrasonic wave;
IV: concentrating the extract to a yellowish-brown extract at 1.32-1.38 (60 ℃) by using a membrane concentration technology, wherein the ratio of bletilla to water is 1 to 4-10, the extraction temperature is 50-90 ℃, and the extraction time is 2-3 hours;
v: and finally, adding purified water, butanediol, pentanediol and other cosolvents to obtain the stable bacteriostatic functional stock solution.
Compared with the prior art, the invention provides a bletilla striata composition with antibacterial and skin care functions and a preparation method thereof, and the bletilla striata composition has the following beneficial effects:
the bletilla striata composition with the antibacterial skin care function and the preparation method thereof are characterized in that forsythia suspense, sophora flavescens, peony root bark and scutellaria baicalensis in main components are mixed, pulverized and subjected to alcohol extraction, the mixture is compressed into thick paste in vacuum, then the rhizoma bletillae is pulverized and subjected to ultrasonic extraction, the extracting solution of the rhizoma bletillae is prepared into a yellow-brown extract by using a membrane concentration technology, and finally the yellow-brown extract is mixed with cosolvents such as purified water, butanediol, pentanediol and the like to prepare a functional stock solution, so that the prepared stock solution can perform a certain protection effect on skin when the antibacterial treatment is performed on the skin.
Detailed Description
Example one
A bletilla striata composition with bacteriostatic and skin-care functions and a preparation method thereof comprise the following steps:
i: the main components are mixed, pulverized and subjected to alcohol extraction, wherein the ratio of fructus forsythiae, radix sophorae flavescentis, peony root bark and radix scutellariae is 1;
II: vacuum compressing the extractive solution to obtain soft extract with relative density of 1.32-1.38 (60) ° C;
III: pulverizing rhizoma Bletillae into powder, adding into hot water solvent, and extracting with ultrasound for 2-3 times;
IV: concentrating to obtain yellowish-brown extract at 1.32-1.38 (60 deg.C) by membrane concentration, wherein the ratio of rhizoma Bletillae to water is 1;
v: and finally, adding purified water, butanediol, pentanediol and other cosolvents to obtain the stable bacteriostatic functional stock solution.
By adopting the method, the skin condition of the human body can be improved, the resistance of the skin of the human body can be improved, and the skin of the human body can be well protected.
Compound proportion and bacteriostasis rate:
in the composition of 100 g of compound formula, the antibacterial rate is optimized according to the dosage of each medicinal material, the antibacterial effect is detected, and the result is as follows:
from the table, by combining the compatibility of the medicinal materials and the result of the antibacterial activity, the preferable composition proportions of the five medicinal materials are as follows: and (3) common bletilla pseudobulb: fructus forsythiae: flavescent sophora root: cortex moutan: scutellaria = 2.
Example two
A bletilla striata composition with bacteriostatic and skin-care functions and a preparation method thereof comprise the following steps:
i: the main components comprise 2, 5, by mass, the ratio of fructus forsythiae to radix sophorae flavescentis to peony root bark to radix scutellariae is 1.6, the ethanol extraction temperature is 80-90 ℃, and the ethanol extraction time is 2.5h;
II: vacuum compressing the extractive solution to obtain soft extract with relative density of 1.32-1.38 (60) ° C;
III: pulverizing rhizoma Bletillae into powder, adding into hot water solvent, and extracting for 2-3 times by ultrasonic wave;
IV: concentrating by membrane concentration technology to obtain yellowish-brown extract at 1.32-1.38 (60 deg.C), wherein the ratio of rhizoma Bletillae to water is 1;
v: and finally, adding purified water, butanediol, pentanediol and other cosolvents to obtain the stable bacteriostatic functional stock solution.
By adopting the method, the skin condition of the human body can be improved, the resistance of the skin of the human body can be improved, and the skin of the human body can be well protected.
Compound proportion and bacteriostasis rate:
in the composition of 100 g of compound formula, the antibacterial rate is optimized according to the dosage of each medicinal material, the antibacterial effect is detected, and the result is as follows:
from the above table, combining the compatibility of each herb and the results of the bacteriostatic activity, we prefer the five herbs to have the following composition ratio: and (3) common bletilla pseudobulb: fructus forsythiae: flavescent sophora root: cortex moutan: scutellaria = 2.
EXAMPLE III
A bletilla striata composition with bacteriostatic and skin-care functions and a preparation method thereof comprise the following steps:
i: the main components are mixed, pulverized and subjected to alcohol extraction, wherein the ratio of the main components to ethanol is 1 percent, 2 to 3;
II: vacuum compressing the extractive solution to obtain soft extract with relative density of 1.32-1.38 (60) ° C;
III: pulverizing rhizoma Bletillae into powder, adding into hot water solvent, and extracting for 2-3 times by ultrasonic wave;
IV: concentrating to obtain yellowish-brown extract at 1.32-1.38 (60 deg.C) by membrane concentration, wherein the ratio of rhizoma Bletillae to water is 1;
v: finally, purified water, butanediol, pentanediol and other cosolvents are added into the mixture to obtain stable bacteriostatic stock solution.
By adopting the method, the skin condition of the human body can be improved, the resistance of the skin of the human body can be improved, and the skin of the human body can be well protected.
Compound proportion and bacteriostasis rate:
in the composition of 100 g of compound formula, the antibacterial rate is optimized according to the dosage of each medicinal material, the antibacterial effect is detected, and the result is as follows:
from the above table, combining the compatibility of each herb and the results of the bacteriostatic activity, we prefer the five herbs to have the following composition ratio: and (3) common bletilla pseudobulb: and (3) fructus forsythiae: kuh-seng: cortex moutan: scutellaria = 2.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. A bletilla striata composition with bacteriostatic and skin-care functions is characterized in that: comprises the following main components: 1-10g of bletilla, 1-10g of fructus forsythiae, 1-10g of radix sophorae flavescentis, 1-10g of peony root bark and 1-10g of radix scutellariae, wherein the main components have the following proportion of 2.
2. The bacteriostatic skin-care function-improving bletilla rubber composition according to claim 1, which is characterized in that: 1-10g of bletilla striata, 1-10g of fructus forsythiae, 1-10g of radix sophorae flavescentis, 1-10g of peony root bark and 1-10g of radix scutellariae, wherein the main components are in a ratio of 1.
3. The bacteriostatic skin-care function-improving bletilla rubber composition according to claim 1, which is characterized in that: 1-10g of bletilla, 1-10g of fructus forsythiae, 1-10g of radix sophorae flavescentis, 1-10g of peony root bark and 1-10g of radix scutellariae, wherein the main components are in a proportion of 2.
4. The bletilla striata composition with bacteriostatic and skin care functions and the preparation method thereof according to claim 1, wherein the preparation method comprises the following steps of:
i: the main components comprise 2;
II: vacuum compressing the extractive solution to obtain soft extract with relative density of 1.32-1.38 (60) ° C;
III: pulverizing rhizoma Bletillae into powder, adding into hot water solvent, and extracting for 2-3 times by ultrasonic wave;
IV: concentrating the extract to a yellowish-brown extract at 1.32-1.38 (60 ℃) by using a membrane concentration technology, wherein the ratio of bletilla to water is 1 to 4-10, the extraction temperature is 50-90 ℃, and the extraction time is 2-3 hours;
v: and finally, adding purified water, butanediol, pentanediol and other cosolvents to obtain the stable bacteriostatic functional stock solution.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210591646.6A CN115300436A (en) | 2022-05-28 | 2022-05-28 | Bletilla striata composition with antibacterial and skin care functions and preparation method thereof |
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| CN202210591646.6A CN115300436A (en) | 2022-05-28 | 2022-05-28 | Bletilla striata composition with antibacterial and skin care functions and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115888510A (en) * | 2023-01-10 | 2023-04-04 | 汕头市奇伟实业有限公司 | Compound natural plant anticorrosion composition and multidirectional differential turbulence preparation method thereof |
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2022
- 2022-05-28 CN CN202210591646.6A patent/CN115300436A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115888510A (en) * | 2023-01-10 | 2023-04-04 | 汕头市奇伟实业有限公司 | Compound natural plant anticorrosion composition and multidirectional differential turbulence preparation method thereof |
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