CN1152467A - Powder medicine for curing recurrence aphtha - Google Patents

Powder medicine for curing recurrence aphtha Download PDF

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CN1152467A
CN1152467A CN 96120287 CN96120287A CN1152467A CN 1152467 A CN1152467 A CN 1152467A CN 96120287 CN96120287 CN 96120287 CN 96120287 A CN96120287 A CN 96120287A CN 1152467 A CN1152467 A CN 1152467A
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radix
medicine
rhizoma
powder
salt
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CN1070060C (en
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李佩洲
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Abstract

The invented drug is mainly used for treating the recurrent aphta. It is composed of salted root of zhejiang figwort 10-30g, salted dried rhizome of rehmannia 10-25g, salted rhizome of wind-weed, 10-25g, rhizome of Chinese atractylodes 5-12g, root of large flowered skullcap 5-12g, Chinese rhubarb 5-12g, rhizome of Chinese goldthread 5-12g, unpeeled root of herbaceous peony 5-12g etc. 12 traditional Chinese medicinal herbs.

Description

The Kouchuang powder for curing aphthosis of treatment recurrent aphtha
The present invention is a kind of Kouchuang powder for curing aphthosis, is Chinese medicine composition, is mainly used in the treatment recurrent aphtha.
Recurrent aphtha is the ulcer sexually transmitted disease (STD) of outbreak change repeatedly on the oral mucosa.Sickness rate height, touching difficulty heal, and about 20% crowd is subjected to this disease invasion and attack certain period in life (1), have a strong impact on people health.In recent years, the treatment of recurrent aphtha is subjected to the attention of Chinese scholars, has obtained many achievements.But be clinical report mostly, Chinese traditional treatment determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs complexity and typing are also lack of standardization, are not easy to clinical practice; Though doctor trained in Western medicine is treated energy respite symptom with hormone, anti-immunizing agent, side effect is big, easily causes the hormone feedback again.So Chinese and western medicine does not all still have specific Therapeutic Method and medicine at present.
The cause of disease and the pathogeny of recurrent aphtha it be not immediately clear.Someone thinks by due to anaphylaxis, viral infection, dyshormonia or the gastrointestinal dysfunction (2)The recurrence inducement is relevant with factors such as dyspepsia, constipation, ascariasis, insomnia fatigue, psychentonia, menstrual cycle, vitamin deficiency, trace element zinc deficiencies.A kind of autoimmune disease is thought in immunology research at present more, points out that the recurrence of modulation on immune status and oral ulcer has substantial connection (3)Also have the scholar to think to be because thereby the virus antigen of invading and cell surface antigen are combined into heteroantigen excites due to the generation autoantibody (4)The inventor thinks by long-term clinical observation: dyspepsia, psychentonia, insomnia fatigue are main risk factors, and about 70% patient has dyshormonia and gastrointestinal dysfunction performance, and tangible heart nourishing kidney-yin syndrome is arranged.As " Longevity and Life Preservation dispute " cloud: " aphtha is person more year after year, and this asthenic fire also "." Shengji Zonglu " cloud and for example; " insufficiency of stomach-QI, few, the empty sun of essence derived from food are upward sent out and be aphtha ... "Modern pathological study thinks that " deficiency of YIN ", " asthenic fire " with neuro dysfunction, especially have substantial connection with the excitement of sympathetic nerve pathologic; With particularly thyroid function disorder of endocrine gland (5)And body's immunity goes down relevant; Relevant with substance metabolismes such as nucleic acid, sugar, protein, lipids with the energy metabolism disorder (6)The inventor is according to the traditional Chinese medical science " the tongue is the orifice to the heart ", " The mouth is the body opening or window of the spleen ", the theory of " it is the tongue basis that the arteries and veins of enough few the moon passes through kidney ", delay difficult for a long time or outbreak repeatedly in conjunction with primary disease, consumption impairment of QI the moon, so that heart spleen kidney yin liquid deficiency, deficiency-fire stirring up, go up scorching dispute, bright Tianjin is an expectorant, and knot was hindered the understanding that film forms primary disease and " pyretic toxicity is given birth to skin ulcer " in phlegm-damp was burning hot.Think that " deficiency of YIN " and " intimately " are the pathological characteristics of recurrent aphtha, be the disease of deficiency in origin and excess in superficiality.The inventor thinks, primary disease cause of disease complexity clinically is difficult to identification, and influences each other between the cause of disease; To the treatment of primary disease, should alleviate local symptom from the enhancing body resistance, promote the principle of ulcer healing to set out, adjust allomeric function, carry out " mark ", " basis " rules together.
The inventor is on the basis of a large amount of clinical practices, found after Radix Scrophulariae, the Radix Rehmanniae, the Rhizoma Anemarrhenae are fried the process of preparing Chinese medicine with salt the treatment recurrent aphtha is had special pearl curative effect in 1984, the other side's medicine constantly screens on this basis, intend for Kouchuang powder for curing aphthosis be applied to clinical, from year July in January, 1988 to 1996 warp 262 routine recurrent aphtha patients are carried out observation of curative effect.The result: Kouchuang powder for curing aphthosis cure rate of the present invention is 64.5%, and total effective rate is 97.33%, through the inventor's nearly 10 years relevant document of checking, does not see that the rule of treatment is identical with the present invention with prescription.With the treatment recurrent aphtha curative effect of generally acknowledging at present medicine preferably, levamisole cure rate 18.33%, total effective rate 68.33% is compared, and Kouchuang powder for curing aphthosis curative effect of the present invention is apparently higher than levamisole and other medicines.Belong to domestic initiation, curative effect has reached advanced international level.
Kouchuang powder for curing aphthosis of the present invention by salt Radix Scrophulariae, the salt Radix Rehmanniae, stir-baked RHIZOMA ANEMARRHENAE before sprinking salt solution, Radix Scutellariae, Rhizoma Coptidis, Radix Et Rhizoma Rhei, Rhizoma Atractylodis, Radix Paeoniae Rubra, Radix Ginseng, Radix Platycodonis, Fructus Aurantii, Radix Glycyrrhizae totally 12 herbal medicines form.Radix Scrophulariae, the Radix Rehmanniae, the Rhizoma Anemarrhenae in the side, are moisturized to promote the production of body fluid and are rushed down asthenic fire at replenishing YIN and removing heat; More help its YIN nourishing eliminating stagnation behind the processed with salt, walk the descending power of kidney.The stomach-fire heat of feeling terribly worried on during Rhizoma Coptidis, Radix Scutellariae are clear; Join the Radix Et Rhizoma Rhei heat-clearing and toxic substances removing, get the property of its bitter cold sedimentation, let out below making inflammation fiery.Radix Paeoniae Rubra is joined the diffusing swollen eliminating carbuncle pain relieving of Radix Et Rhizoma Rhei cooling blood and removing stasis.The Fructus Aurantii promoting the circulation of QI to alleviate the stagnation in middle-JIAO removes and expands; Join the dehumidifying of purging heat of Radix Et Rhizoma Rhei, Radix Scutellariae, Rhizoma Coptidis, consumer product dredge stasis.Eliminate the phlegm moistening and cleaning throat, priming of Radix Platycodonis is up.Sun-dried many " tonifying five ZANG-organs is pacified spirit, " boosting qi and nourishing yin is inspired taste vigour; Join Rhizoma Atractylodis, the removing dampness of Radix Glycyrrhizae spleen benefiting and stimulating the appetite.And Radix Ginseng, Radix Glycyrrhizae stomach reinforcing protect Tianjin, make the agent in big bitter Great Cold and the worry of not damaged taste.Herbal pharmacology is thought: the Radix Rehmanniae, Radix Scrophulariae have the effect of the nucleic acid synthetic ratio of two-way adjustment " deficiency of YIN " animal model, and the liver spleen nucleic acid metabolism obstacle that hormone is caused has Accommodation, and interior DNA of cell and RNA synthetic ratio are transferred to normally.Join the nonspecific resistance of Radix Ginseng energy enhancing body, make disorderly functional recovery normal various destructive stimuluses (7)The Rhizoma Anemarrhenae can reduce neural irritability (8)Radix Ginseng can be strengthened corticocerebral process of excitation and process of inhibition, makes excited and suppress two kinds of processes to obtain balance, makes anxiety cause disorderly nervous process to be recovered, and is all effective in cure to vegetative nerve and various nervous disorder; And significant antifatigue effect arranged; Can also the endocrine regulation disorder; Substance metabolism such as sugar, protein, lipid and energy metabolism had improve and facilitation (9)Radix Glycyrrhizae has the effect of adrenocortical hormone sample, can strengthen the hormonal system function, and obvious facilitation is arranged when Abwehrkraft des Koepers is subjected to consuming (10)Radix Glycyrrhizae, Radix Ginseng, Radix Et Rhizoma Rhei, Radix Scutellariae, Rhizoma Coptidis, Rhizoma Atractylodis are energy enhancing human body immunity function all, improves body resistance against diseases, helps immunomodulating (11)Radix Scutellariae, Radix Ginseng, Radix Glycyrrhizae have anti-allergic effects.Radix Scutellariae, Rhizoma Coptidis, Radix Paeoniae Rubra have antivirus action (12)The Rhizoma Anemarrhenae, that Rhizoma Coptidis contains zinc is more, and bacterial virulence is weakened, and quicken inflammation and disappear, thereby alleviate the infringement of tissue (13)Radix Platycodonis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae, Cang Shui eliminate the phlegm.Radix Platycodonis, Radix Glycyrrhizae, Radix Paeoniae Rubra have antiulcer action, can impel inflammation to take a turn for the better early, prevent that mucosa is subjected to environmental stimuli (14)Fructus Aurantii, Radix Ginseng, Rhizoma Atractylodis can strengthen gastrointestinal motility, and the digestant effect of being good for the stomach is arranged (15)Remove this, Radix Et Rhizoma Rhei, Radix Paeoniae Rubra, Radix Platycodonis, Radix Glycyrrhizae, Radix Scutellariae, Rhizoma Coptidis, the Rhizoma Anemarrhenae, Radix Ginseng, Rhizoma Atractylodis all have anti-inflammatory and antalgic, sedation, can effectively alleviate local symptom.More than all medicine compatibilities, reinforcing and reducing concurrently, giving consideration to both the incidental and fundamental are played replenishing YIN and removing heat, eliminating fire and detoxication, invigorating the spleen for eliminating dampness, removing heat from blood altogether and are eliminated the phlegm, promote ulcer healing, adjust allomeric function, the effect of human body immunity improving function.Pathological characteristic at recurrent aphtha " deficiency of YIN ", " intimately ", at anaphylaxis, viral infection, dyshormonia, gastrointestinal dysfunction, body's immunity go down, the causes of disease such as psychentonia, insomnia fatigue, trace element zinc deficiency, the medicine card conforms to and recovers.
The present invention's purpose provides a kind of Kouchuang powder for curing aphthosis.Another purpose of the present invention provides a kind of preparation method of Kouchuang powder for curing aphthosis.
Kouchuang powder for curing aphthosis medicine of the present invention is formed: Radix Scrophulariae 10-30g, Radix Rehmanniae 10-25g, Rhizoma Anemarrhenae 10-25g, grey water 5-12g, Radix Scutellariae 5-12g, Radix Et Rhizoma Rhei 5-12g, Rhizoma Coptidis 5-12g, Radix Paeoniae Rubra 5-12g, Radix Ginseng 5-10g, Radix Platycodonis 5-10g, Fructus Aurantii 5-15g, Radix Glycyrrhizae 5-12g.The preferred dose that the Kouchuang powder for curing aphthosis medicine is formed: profound many 15-25, Radix Rehmanniae 8-15g, Rhizoma Anemarrhenae 10-20g, Rhizoma Atractylodis 5-8g, Radix Scutellariae 5-8g, Radix Et Rhizoma Rhei 5-8g, Rhizoma Coptidis 5-8g, Radix Paeoniae Rubra 5-8g, Radix Ginseng 5-8g, Radix Platycodonis 5-8g, Fructus Aurantii 5-12g, Radix Glycyrrhizae 5-Bg.By dosage in the side, the Rhizoma Anemarrhenae, Radix Scrophulariae, the Radix Rehmanniae are fried till the medicine jaundice with frying with salt 50-100g (sea salt that does not add iodine) slow fire heating in iron pan respectively, medicine is chosen, salt stay time fry medicinal.Top dosage is amplified (Chinese medicine is from medical material company) in proportion arbitrarily, be processed into superfine powder with pulverizer and cross 100 mesh sieves, the remaining minute quantity Chinese medicine in back slightly not (account for total amount 1/15) sieves, an amount of with tap water, soaked after 30 minutes in big marmite slow fire boiling 30 minutes, leach medicinal liquid, make binding agent with this medicinal liquid, spray medicated powder and in finisher,pill, be processed into the Semen phaseoli radiati bolus, air-dry with 35 ℃ of-40 ℃ of temperature bakings then, pack standby.
The patient began to take medicine in the recurrence phase, and the adult is for oral administration by each 10Kg body weight 2-3g dosage, and general adult measures each 10g, obeyed every day 3 times, and warm water delivery service after meal changes into after serveing on 30 days and waits day clothes 2 times, serve on drug withdrawal in 2 months observation.Kouchuang powder for curing aphthosis of the present invention is examined for bearing's square gauge, is intended to observe special side's definite effect, evaluates curative effect after 1 year.Allly take the other medicines therapist again, do not take in the summary case at viewing duration.
Observed result shows that Kouchuang powder for curing aphthosis of the present invention is compared with existing medicine and had the following advantages: the medicine that 1, has overcome present treatment recurrent aphtha is only at a certain cause of disease, and generality is poor, the situation that adaptability is little.Kouchuang powder for curing aphthosis of the present invention is to set about from adjusting allomeric function, and at all multi-pathogenesis, generality is strong, wide adaptability, and the pathological characteristic of outstanding " deficiency of YIN ", " intimately " is with guiding principle band order, treating both the principal and the secondary aspects of a disease at the same time.2, determined curative effect, cure rate 64.5%, total effective rate reaches 97.33%, has no side effect, and the effect of its control recurrence is significantly higher than levamisole and other medicine.3, taking convenience has overcome that present local topical and buccal medicine thing are taken frequently, stimulating mucosal, increases the painful weakness of trouble again to the patient, and the patient is willing to accept.4, the medicine source is abundant, and the medicine valency is cheap, because of recurrent aphtha sickness rate height, so socialbenefit and economic effect will be very considerable.
The inventor is in out-patient's Chinese medicine decoction treatment is observed, and has found that medicines such as the Rhizoma Anemarrhenae, Radix Scrophulariae, the Radix Rehmanniae are good to treatment recurrent aphtha effect.But its property of medicine bitter cold is moistened, and has laxation to help wet greasy diaphragm to hinder the fraud of stomach, so parch relaxes its property of medicine, stir-fry makes its property of medicine walk the descending power that can strengthen replenishing YIN and removing heat, eliminating stagnation pathogenic fire reducing again of kidney with salt, competes to have received special pearl curative effect.On this basis, to the prescription medicine repeated screening, powder is concocted in the fixing processing of prescription in 1988.The present invention below will be described in detail with the form of embodiment, but can not be with this as the restriction to the present invention.
Embodiment:
Example 1: Radix Scrophulariae 30g, Radix Rehmanniae 25g, Rhizoma Anemarrhenae 25g, Rhizoma Atractylodis 12g, Radix Scutellariae 12g, Radix Et Rhizoma Rhei 12g, Rhizoma Coptidis 12g, Radix Paeoniae Rubra 12g, Radix Ginseng 10g, Radix Platycodonis 10g, Fructus Aurantii 15g, Radix Glycyrrhizae 12g.By dosage in the side, the Rhizoma Anemarrhenae, Radix Scrophulariae, the Radix Rehmanniae are fried till the medicine jaundice with frying with salt 100g (sea salt that does not add iodine) slow fire heating in iron pan respectively, and medicine is chosen.Top dosage is amplified (Chinese medicine is from medical material company) arbitrarily in this ratio, be processed into superfine powder with pulverizer, cross 100 mesh sieves, the remaining minute quantity Chinese medicine coarser powder in back (account for total amount 1/15) that sieves soaked after 30 minutes in big cauldron slow fire boiling 30 minutes with tap water is an amount of, leached medicinal liquid, make binding agent with this medicinal liquid, spray medicated powder and in finisher,pill, be processed into the Semen Glycines bolus, air-dry with 70 ℃ of-90 ℃ of temperature bakings then, pack standby.
The patient began to take medicine in the recurrence phase.The adult is for oral administration by each 10Kg body weight 2g-3g dosage, and general adult measures each 10g, obeys every day 3 times, and warm water delivery service serve on drug withdrawal in 2 months and observes after meal.Observe through 36 routine patients, curative effect was rapid after the patient took medicine, cure rate 64.45%, effective percentage 97.3%, inefficiency 2.7%.But at period in a medicine, about 10% patient has diarrhea to some extent, the abdominal distention symptom.
Example 2: Radix Scrophulariae 25g, Radix Rehmanniae 15g, Rhizoma Anemarrhenae 18g, Rhizoma Atractylodis 8g, Radix Scutellariae 8g, Rhizoma Coptidis 8g, Radix Et Rhizoma Rhei 10g, Radix Paeoniae Rubra 8g, Radix Ginseng 6g, Radix Platycodonis 6g, Fructus Aurantii 10g, Radix Glycyrrhizae 8g, by dosage in the side, the Rhizoma Anemarrhenae, Radix Scrophulariae, the Radix Rehmanniae are fried together with salt 80g (sea salt that does not add iodine) slow fire heating in iron pan respectively, fry till the medicine jaundice, medicine is chosen.Top dosage is amplified (Chinese medicine is from medical material company) arbitrarily in this ratio, be processed into superfine powder with pulverizer, cross 100 mesh sieves, the remaining minute quantity Chinese medicine coarser powder in back (account for total amount 1/15) that sieves, an amount of with tap water, soaked after 30 minutes in big marmite slow fire boiling 30 minutes, leach medicinal liquid, make binding agent, spray medicated powder and in finisher,pill, be processed into the Semen phaseoli radiati bolus with this medicinal liquid, air-dry with 35 ℃ of-40 ℃ of temperature bakings then, pack standby.
The patient began to take medicine in the recurrence phase.The adult is for oral administration by each 10Kg body weight 2g-3g dosage, and general adult measures 10g female time, obeys every day 3 times, and warm water delivery service after meal changes into after serveing on 30 days and obeys 2 every day, serve on drug withdrawal in 2 months and observes.Observe the curative effect of taking medicine and example 1 no significant difference through 40 routine patients.Period in a medicine, about 8% patient has loose stool, abdominal distention symptom.
Example 3: Radix Scrophulariae 20g, Radix Rehmanniae 10g, Rhizoma Anemarrhenae 15g, Rhizoma Atractylodis 6g, Radix Scutellariae 6g, Rhizoma Coptidis 6g, Radix Et Rhizoma Rhei 6g, Radix Paeoniae Rubra 6g, Radix Ginseng 6g, Radix Platycodonis 5g, Fructus Aurantii 10g, Radix Glycyrrhizae 6g, by dosage in the side, the Rhizoma Anemarrhenae, Radix Scrophulariae, the Radix Rehmanniae are fried together with salt 50g (sea salt that does not add iodine) slow fire heating in iron pan respectively, fry till the medicine jaundice, medicine is chosen.Processing method is identical with example 2.
The medication dose method is identical with example 2.Observe through 186 routine patients, the curative effect of taking medicine is better than example 2.Cure rate 64.52%, effective percentage 97.34%, inefficiency 2.66%.After taking medicine, the patient do not see malaise symptoms.About 5% patient has slight loose stool symptom.
Kouchuang powder for curing aphthosis is observed through 262 routine patients, does not meet quick and any toxic and side effects.
Kouchuang powder for curing aphthosis of the present invention is concocted the points for attention in the processing: 1, Chinese medicine can not have and goes mouldy, damages by worms, and quality is with authentic superior being as the criterion in the place of production.Dosage be meant Chinese medicine adopted choose, choose, winnow with a dustpan, methods such as sieve, Exposure to Sunlight, remove grey bits, impurity, moisture content and non-medicinal part, make medicine clean purified part.2, the Rhizoma Anemarrhenae, Radix Scrophulariae, the Radix Rehmanniae are fried together with salt respectively in the prescription, to fry to the little yellow of medicine degree of being, can not become charcoal by parching to brown.3, after medicated powder is processed into pill, must be air-dry with interior baking at 48 hours, instant pack, sealed damp-proof.
Case summary:
Case is selected: 1, oral ulcer has typical cyclic recurrence person.2, medical history is recurring person more than 4 times more than 1 year and in 1 year.3, traumatic ulcer, oral leukoplakia, syphilis oral ulcer, oral cancer patient are as observing case.
All cases are all from the clinic case in year July in January, 1988 to 1996, go to a doctor according to the patient and successively make the patient medical history record, make diagnosis recording.Observe 262 examples altogether, male 125 examples, women 137 examples.16-30 year 67 examples wherein, 31-40 year 94 examples, 41-50 year 75 examples, 26 examples more than 50 years old.Medical history 1-2 56 examples, 3-5 71 examples, 6-9 66 examples, 69 examples more than 9 years.
Therapeutic outcome:
One, efficacy assessment standard: 1, cure not recurrence in a year.2, produce effects: recurrence is no more than 2 times in 1 year, and symptom obviously alleviates.3, take a turn for the better: recurrent number obviously reduces before the treatment in 1 year.4, invalid: recurrent number does not have obvious the minimizing before the treatment in 1 year.
Two, efficacy result: observe 262 examples, cure 169 examples, account for 64.50%, produce effects 52 examples account for 19.85%, and 34 examples that take a turn for the better account for 12.98%, and invalid 7 sides account for 2.67%.
Observe the curative effect is table as a result
Total routine number Cure Produce effects Take a turn for the better Invalid Effectively total
Example ????262 ??16g ???52 ???34 ????7 ????255
??% ????100 ??64.5% ???19.85% ???12.98% ????2.67% ????97.33%
Three, model case:
Grandson * *, woman, 46 years old.Nineteen ninety-five first visit on June 26, the main suit: the oral cavity sick pain of bursting was shown effect 20 years repeatedly, whenever sent out because of fatigue or spirit depressing, and each outbreak continues not wait in 10-20 days, surplus the annual recurrence 10 time, shows effect repeatedly in this year, and this disappears, and that rises.Normal companion's dry pharynx pain, fidgety, anorexia, insomnia, stool are not smooth.Once do not have with vitamin, multiple antibiotics, hormone and Chinese medicine multi-treatment and be clearly better, check: in red tongue, yellow fur thin few Tianjin, the tip of the tongue tongue limit and the lower lip 5 place's ulcer points are arranged, each about 0.3cm * 0.4cm, shows to drape over one's shoulders yellow film, mucosa blush on every side at concavity, the causalgia sense is arranged, thready and rolling pulse.Be diagnosed as recurrent aphtha, dialectical is deficiency of YIN phlegm-fire, the last scorching film that burns, and it is for oral administration to give Kouchuang powder for curing aphthosis, and each 10g, serve on five days, taking medicine after meal at every day three times.Further consultation on July 1, the patient likes and accuses clothes and promptly took a favorable turn in two days, and now good entirely, inspection: ulcer has healed, pale tongue with thin fur, six kinds of pulses is gentle, changes into after advising it to adhere to taking medicine 30 days and obeying every day 2 times, serve on 2 months.Accused afterwards in 2 months and do not recur.Advise it tired, keeps happy, the drug withdrawal observation is followed up a case by regular visits to and was not surplusly seen recurrence in 1 year.

Claims (3)

1, a kind of Kouchuang powder for curing aphthosis compositions for the treatment of recurrent aphtha is characterized in that the ratio composition of said composition in salt Radix Scrophulariae 10-30g, salt Radix Rehmanniae 10-25g, stir-baked RHIZOMA ANEMARRHENAE before sprinking salt solution 10-25g, Rhizoma Atractylodis 5-12g, Radix Scutellariae 5-12g, Radix Et Rhizoma Rhei 5-12g, Rhizoma Coptidis 5-12g, Radix Paeoniae Rubra 5-12g, Radix Ginseng 5-10g, Radix Platycodonis 5-10g, Fructus Aurantii 5-15g, Radix Glycyrrhizae 5-12g.
2, preparation Kouchuang powder for curing aphthosis method for compositions, it is characterized in that getting Radix Scrophulariae 10-30g, Radix Rehmanniae 10-25g, Rhizoma Anemarrhenae 10-25g fries together with salt 50-100g (sea salt that does not add iodine) slow fire heating in iron pan respectively, fry till the medicine jaundice, medicine is chosen and Rhizoma Atractylodis 5-12g, Radix Scutellariae 5-12g, Radix Et Rhizoma Rhei 5-12g, Rhizoma Coptidis 5-12g, Radix Paeoniae Rubra 5-12g, Radix Ginseng 5-10g, Radix Platycodonis 5-10g, Fructus Aurantii 5-15g, Radix Glycyrrhizae 5-12g combination, be processed into extremely fine powder with pulverizer, cross 100 mesh sieves, back remaining plate a small amount of Chinese medicine coarser powder (account for total amount 1/15) sieves, an amount of with tap water, soaked after 30 minutes in big marmite slow fire boiling 30 minutes, leach medicinal liquid, make binding agent with this medicinal liquid, spray medicated powder and in finisher,pill, be processed into the Semen phaseoli radiati bolus, air-dry with 35 ℃ of-40 ℃ of temperature bakings then, pack.
3, according to the method for claim 2, with the Chinese medicine of respectively distinguishing the flavor of in the Kouchuang powder for curing aphthosis compositions in the production of amplifying arbitrarily, feed intake of described ratio.
CN96120287A 1996-11-05 1996-11-05 Powder medicine for curing recurrence aphtha Expired - Fee Related CN1070060C (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006181A1 (en) * 1998-07-24 2000-02-10 Jinchu Lan A medicament for treating recurrent ulcer of mouth and behcet's syndrome
CN101085240B (en) * 2007-06-29 2010-06-09 李永红 Oral decoction for treating aphtha
CN103417809A (en) * 2013-08-10 2013-12-04 张安美 TCM preparation for treatment of thrush in infants and children
CN103432471A (en) * 2013-08-17 2013-12-11 马建国 Medicinal power for treating aphtha and preparation method of medicinal power
CN105434906A (en) * 2014-09-26 2016-03-30 韦栩原 Drug for treatment of mouth and tongue sore
CN106880731A (en) * 2015-12-15 2017-06-23 韦翔鹏 A kind of Kouchuang powder for curing aphthosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1078896A (en) * 1992-12-31 1993-12-01 许中伟 External application cream for mouth ulcer
CN1094298A (en) * 1993-04-28 1994-11-02 薜爱玲 Aphtha fast recovery powder and compound method thereof
CN1098299A (en) * 1993-08-04 1995-02-08 赵世平 The sweet cool Kouchuang powder for curing aphthosis and the compound method thereof that are used for recurrent aphtha and all kinds of aphthas
CN1104512A (en) * 1993-12-28 1995-07-05 西南民族学院 Medicine powder for aphtha
CN1056757C (en) * 1995-01-23 2000-09-27 福建中医学院 Method for producing instant pearl granule for treatment of aphtha
CN1052645C (en) * 1995-08-08 2000-05-24 温治亭 Traditional Chinese medicine "Zhenhuang" powder and its production method

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006181A1 (en) * 1998-07-24 2000-02-10 Jinchu Lan A medicament for treating recurrent ulcer of mouth and behcet's syndrome
CN101085240B (en) * 2007-06-29 2010-06-09 李永红 Oral decoction for treating aphtha
CN103417809A (en) * 2013-08-10 2013-12-04 张安美 TCM preparation for treatment of thrush in infants and children
CN103417809B (en) * 2013-08-10 2014-10-22 张安美 TCM preparation for treatment of thrush in infants and children
CN103432471A (en) * 2013-08-17 2013-12-11 马建国 Medicinal power for treating aphtha and preparation method of medicinal power
CN105434906A (en) * 2014-09-26 2016-03-30 韦栩原 Drug for treatment of mouth and tongue sore
CN106880731A (en) * 2015-12-15 2017-06-23 韦翔鹏 A kind of Kouchuang powder for curing aphthosis

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