CN115192655A - Traditional Chinese medicine oral liquid and preparation method and application thereof - Google Patents

Traditional Chinese medicine oral liquid and preparation method and application thereof Download PDF

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CN115192655A
CN115192655A CN202210746135.7A CN202210746135A CN115192655A CN 115192655 A CN115192655 A CN 115192655A CN 202210746135 A CN202210746135 A CN 202210746135A CN 115192655 A CN115192655 A CN 115192655A
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solution
parts
oral liquid
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preparing
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宋曼玲
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention relates to a traditional Chinese medicine oral liquid, a preparation method and application thereof, belonging to the technical field of traditional Chinese medicines. The oral liquid comprises the following components in parts by weight: 5-50 parts of masson pine pollen concentrated solution, 2-30 parts of gynostemma pentaphylla solution, 1-10 parts of hawthorn solution, 1-5 parts of pearl powder aqueous solution and 1-5 parts of medlar solution, and the preparation method comprises the steps of mixing and stirring the components uniformly; the invention is used for eliminating gastrointestinal diseases, adopts pure traditional Chinese medicines for treatment, has no toxic or side effect, has good clinical curative effect, can completely reduce the use of antibiotics and surgical treatment of patients, and avoids the toxic or side effect of western antibacterial medicines and the injury caused by the surgery.

Description

Traditional Chinese medicine oral liquid and preparation method and application thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine oral liquid as well as a preparation method and application thereof.
Background
Gastrointestinal diseases belong to common diseases and are also high-risk diseases. The existing treatment methods are only surgical and western medicine treatment methods, and lack specificity, and the surgical and western medicines have certain damage and toxic and side effects on human bodies.
Pine pollen is the male spore of pine, integrates the essence of pine, contains more comprehensive nutrient substances, and has complete proteins, amino acids, mineral substances, vitamins, nucleic acids, flavones, unsaturated fatty acids, enzymes and the like which are necessary for human bodies, rich content, reasonable proportion and high nutritional value. The China people have two thousand years of history of eating the pollen pini, and the pollen pini is listed as the pollen which can be used as both medicine and food in ancient medical literature and modern pharmacopoeia. Like the first pharmacopoeia of China, shen nong Ben Cao Jing, pine pollen is listed as a superior health-preserving product, a health-care longevity medicine. Tang & lt & ltNew repair materia Medica & gt, ming Li Shizhen & lt & gt compendium of materia Medica & gt, yuan and Ming-term food channel and the like all have high evaluation on pollen Pini: the pine pollen is warm, sweet, mild and nontoxic, has the effects of moistening heart and lung, nourishing qi, beautifying, dispelling wind, stopping bleeding, and reducing weight and prolonging life after long-term use. The pharmacopoeia of the people's republic of China and the compilation of Chinese herbal medicines are also recorded: pollen Pini is sweet and warm, nontoxic, astringent, and hemostatic, and can be used for treating gastric ulcer, duodenal ulcer, and hemoptysis.
The masson pine is a unique tree species in China, is an evergreen needle-leaved large tree with long life, has the tree age of thousands of years, and is a fine product in pine pollen. Aiming at the problems that the existing chemical drugs have side effects or toxicity to human bodies to a greater or lesser extent, the inventor of the invention is continuously dedicated to the development and research of the pinus massoniana lamb pollen, and the pinus massoniana lamb pollen is taken as the main raw material, so that through scientific formula, the development of a traditional Chinese medicine which can eliminate gastrointestinal diseases and is beneficial and harmless to the health of human bodies is needed.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: the traditional Chinese medicine oral liquid and the preparation method and the application thereof are provided, so that the defects of the prior art are overcome, no toxic or side effect is caused, the clinical curative effect is good, the use of antibiotics and surgical treatment of a patient can be completely reduced, and the toxic or side effect of western antibacterial drugs and the injury caused by the surgery are avoided.
The technical scheme adopted by the invention is as follows:
a traditional Chinese medicine oral liquid comprises the following components in parts by weight: 5-50 parts of pine pollen concentrated solution, 2-30 parts of gynostemma pentaphylla solution, 1-10 parts of hawthorn solution, 1-5 parts of pearl powder aqueous solution and 1-5 parts of medlar solution.
Further, the traditional Chinese medicine oral liquid comprises, by weight, 50 parts of pine pollen concentrated solution, 30 parts of gynostemma pentaphylla solution, 10 parts of hawthorn solution, 5 parts of pearl powder aqueous solution and 5 parts of wolfberry fruit solution.
Further, the pine pollen in the pine pollen concentrated solution adopts refined horsetail pine pollen.
A preparation method of a traditional Chinese medicine oral liquid comprises the following steps:
a. preparing a pollen pini concentrated solution: drying pollen Pini, extracting nutrient solution, sequentially performing rough filtration, fine filtration, concentration, blending, filling, sterilization, labeling, packaging, sampling inspection, and warehousing;
b. preparing gynostemma pentaphylla solution according to the proportion of 1:20 parts of the raw materials are added with water for decoction, the liquid is poured out after the first decoction is carried out for 2 hours, and the weight is calculated according to the following steps of 1: adding water in a proportion of 20, boiling for 1 hour, pouring out the liquid, mixing the two times of liquid, boiling or concentrating, taking the concentrated liquid as 10 times of the raw material, filtering, pouring a pot, sealing and putting the pot into a cold storage for later use; respectively preparing the hawthorn juice and the medlar juice by the same method;
c. preparing a pearl powder aqueous solution, dissolving the instant pearl powder with purified water according to the proportion of 1;
d. mixing the prepared pollen Pini concentrated solution, herba Gynostemmatis solution, fructus crataegi solution, margarita powder water solution, and fructus Lycii solution, stirring, and making into the Chinese medicinal oral liquid.
Further, the sensory indexes of the pine pollen concentrated solution in the step a are as follows: (1) the appearance is light brown yellow translucent liquid; (2) the pine pollen has unique flavor, and is sour, sweet and delicious; (3) the long-term storage at room temperature allows a small amount of precipitation and no peculiar smell.
Further, the physical and chemical indexes of the pollen pini concentrated solution in the step a are as follows: (1) the sugar content is less than 50 percent; (2) the PH value is 4-4.5; (3) the plum degree of the concentrated solution is about 12 degrees Be; (4) the mg/Kg of lead (calculated by Pb) is less than or equal to 1; (5) arsenic (calculated As As) mg/Kg is less than or equal to 1.
Further, the microorganism indexes of the pine pollen concentrated solution in the step a are as follows: (1) total number of colonies: (cfu/g) is less than or equal to 100; (2) coliform group bacteria: (MPN/100 g) is less than or equal to 30; (3) total number of molds: (cfu/g) is less than or equal to 10; (4) pathogenic bacteria: and cannot be detected.
Further, the application of the traditional Chinese medicine oral liquid is applied to the treatment of gastrointestinal diseases.
The beneficial effects of the invention are: the traditional Chinese medicine oral liquid formula provided by the invention has the advantages that the compatibility of the traditional Chinese medicine oral liquid formula accords with the principle of monarch, minister, assistant and guide of the traditional Chinese medicine, the number of the medicines is small, the preparation method is simple and easy to implement, the gastrointestinal tract diseases can be eliminated by adopting pure traditional Chinese medicine treatment, the traditional Chinese medicine oral liquid formula has a good clinical curative effect, has no toxic or side effect, can obviously reduce the use of antibiotics for gastrointestinal tract disease patients, and avoids the toxic or side effect of western antibacterial drugs and the injury caused by operation.
Detailed Description
The following examples are provided to illustrate specific embodiments of the present invention.
A traditional Chinese medicine oral liquid comprises the following components in parts by weight: 5-50 parts of masson pine pollen concentrated solution, 2-30 parts of gynostemma pentaphylla solution, 1-10 parts of hawthorn solution, 1-5 parts of pearl powder aqueous solution and 1-5 parts of medlar solution.
The compatibility of the oral liquid formula accords with the principle of 'monarch, minister, assistant and guide' of the traditional Chinese medicine. The masson pine pollen concentrated solution in the formula is used as genetic material of Pinus plants, not only contains various amino acids, vitamins, mineral substances, enzymes, and nutrient components and active substances such as nucleic acid, unsaturated fatty acid, lecithin, flavonoid, monosaccharide, polysaccharide and the like, but also has reasonable proportion and is called a micro nutrient bank. Meanwhile, the health-care tea has the functions of resisting aging and fatigue, regulating gastrointestinal functions, protecting liver, maintaining cardiovascular system, promoting growth and development, greatly improving the autoimmunity of human bodies and regulating organism functions.
The gynostemma pentaphylla liquid is cold in nature, bitter in taste and slightly sweet. Has the functions of clearing away heat and toxic material, relieving cough, eliminating phlegm, invigorating spleen and reinforcing deficiency.
The hawthorn juice is slightly warm in nature, sour and sweet in taste. Has the functions of promoting digestion, invigorating stomach, promoting qi circulation, dissipating blood stasis, eliminating turbid pathogen and reducing blood fat.
The wolfberry fruit juice has sweet taste, neutral nature and liver nourishing, kidney nourishing and lung moistening effects.
The pearl powder aqueous solution is sweet, salty and cold in nature. It enters heart and liver meridians. Has the functions of tranquilizing, arresting convulsion, improving eyesight, eliminating nebula, detoxicating, promoting granulation, moistening skin and removing spots.
The pharmacological analysis of the invention: the pollen pini liquid in the formula has various nutrient components and active substances of a human body, and has the functions of regulating, maintaining, promoting and improving the immunity and the organism; the gynostemma pentaphylla liquid has the functions of clearing away heat and toxic material, relieving cough, eliminating phlegm, invigorating spleen and tonifying deficiency; the hawthorn juice has the functions of promoting digestion, invigorating stomach, promoting qi circulation, removing blood stasis, eliminating turbid pathogen and reducing blood fat; the medlar liquid has the functions of soothing the liver, nourishing the kidney and moistening the lung; the pearl powder aqueous solution has the functions of calming the nerves, arresting convulsion, improving eyesight, eliminating nebula, detoxifying, promoting granulation, moistening skin and removing freckles. The whole formula has the effect of eliminating gastrointestinal diseases.
The preparation method of the traditional Chinese medicine oral liquid comprises the following steps:
a. preparing a pollen pini concentrated solution: drying pollen Pini, extracting to obtain nutrient solution, sequentially performing rough filtration, fine filtration, concentration, blending, bottling, sterilization, labeling, packaging, sampling inspection, and warehousing.
Wherein the sensory indexes of the pine pollen concentrated solution are as follows: (1) the appearance is light brown yellow translucent liquid; (2) has the unique flavor of the pine pollen and is sour, sweet and delicious; (3) the long-term storage at room temperature allows a small amount of precipitation and no peculiar smell.
The physical and chemical indexes of the pollen pini concentrated solution are as follows: (1) the sugar content is less than 50 percent; (2) the PH value is 4-4.5; (3) the plum degree of the concentrated solution is about 12 degrees Be; (4) the mg/Kg of lead (calculated by Pb) is less than or equal to 1; (5) arsenic (calculated As As) mg/Kg is less than or equal to 1.
Wherein the microorganism indexes of the pollen pini concentrated solution are as follows: (1) total number of colonies: (cfu/g) is less than or equal to 100; (2) coliform group bacteria: (MPN/100 g) is less than or equal to 30; (3) total number of molds: (cfu/g) is less than or equal to 10; (4) pathogenic bacteria: and cannot be detected.
b. Preparing gynostemma pentaphylla solution according to the proportion of 1: decocting with water at a ratio of 20, decocting for 2 hr, and pouring out the decoction according to the ratio of 1: adding water in a proportion of 20, boiling for 1 hour, pouring out the liquid, mixing the two liquids, boiling or concentrating, taking the concentrated liquid as 10 times of the raw material, filtering, pouring into a pot, sealing and putting into a cold storage for later use; the hawthorn juice and the medlar juice are respectively prepared by the same method.
c. Preparing a pearl powder aqueous solution, dissolving the instant pearl powder with purified water according to the proportion of 1.
d. Mixing the prepared pollen Pini concentrated solution, herba Gynostemmatis solution, fructus crataegi solution, margarita powder water solution, and fructus Lycii solution, and stirring to obtain the Chinese medicinal oral liquid.
The first embodiment is as follows:
a Chinese medicinal oral liquid comprises (by weight parts) pollen Pini concentrate 50, herba Gynostemmatis liquid 30, fructus crataegi liquid 10, margarita powder aqueous solution 5, and fructus Lycii liquid 5.
Example two;
a traditional Chinese medicine oral liquid comprises, by weight, 30 parts of masson pine pollen concentrated solution, 20 parts of gynostemma pentaphylla solution, 6 parts of hawthorn solution, 3 parts of pearl powder aqueous solution and 3 parts of medlar solution.
Example three:
a traditional Chinese medicine oral liquid comprises, by weight, 15 parts of masson pine pollen concentrated solution, 6 parts of gynostemma pentaphylla solution, 2 parts of hawthorn solution, 1 part of pearl powder aqueous solution and 1 part of medlar solution.
Example four:
a Chinese medicinal oral liquid comprises (by weight parts) pollen Pini concentrate 5, herba Gynostemmatis liquid 2, fructus crataegi liquid 1, margarita powder aqueous solution 1, and fructus Lycii liquid 1.
Example five:
main pharmacodynamic tests: test report of fatigue resistance of pine pollen extract to mice
1. Materials and methods
1. The masson pine pollen extract is 2000g of pure masson pine pollen which is processed by impurity removal, drying and the like, extracted by a scientific method and concentrated to 2000ml of water-soluble pollen extract without any additive;
NIH mice, female, weight 15-17 g, according to the weight pairing random grouping. The experiment is carried out in two batches, 20ml of pine pollen extracting solution/kg and 15ml of pine pollen extracting solution/kg are respectively used, the pine pollen extracting solution is mixed in a small amount of feed before being fed with common feed every day, the mixture is continuously fed for 30 days, and the anti-fatigue test is carried out on each group of mice.
2. Results of the experiment
1. Mouse rod rotation test
The mouse is put on a rotating electric rotating rod with 12 revolutions per minute, so that the mouse is forced to continuously run quickly. The time from the mouse being placed on the rotating bar to the fatigue drop rotating bar was recorded as the mouse rotating bar time. The results are shown in Table 1:
TABLE 1
Figure RE-RE-DEST_PATH_IMAGE002
2. Mouse swimming test
The mouse is loaded with 0.7 g/mouse and put into a jar with water depth of 40cm and water temperature of 30 +/-1 ℃ to force the mouse to swim and struggle. The time from the beginning of swimming to the time when the physical strength is exhausted and sinks for 10 seconds and then does not float out of the water surface is recorded as the swimming time of the mice. The results are shown in Table 2:
TABLE 2
Figure RE-RE-DEST_PATH_IMAGE004
3. Conclusion of the experiment
As can be seen from Table 1, the endurance of the pollen pini extract group is improved by 46.6-101% compared with that of the control group in the mouse rod-rotating test;
as can be seen from the table 2, in the mouse swimming test, the endurance of the pine pollen extracting solution group is improved by 56.8 to 77.6 percent compared with that of the control group;
the experimental result shows that the pollen pini extract can obviously prolong the rod rotating time and the swimming time of a mouse and greatly improve the exercise endurance, which cannot be achieved by the common bee pollen extract. The pine pollen extract can play an important role in promoting metabolism, increasing energy, improving endurance of athletes, nourishing and protecting health of middle-aged and elderly people, and the like.
Example six:
when the traditional Chinese medicine formula provided by the embodiment of the invention is applied to the treatment process of gastrointestinal diseases, more patients are cured, and representative patient information is listed here.
Case 1:
in 8 years old, a moustache, a woman and an engineer in the age of 48 have no stool form, the stool is taken several times every day, the complexion is pale, and the human body is thin. After the traditional Chinese medicine oral liquid with the formula is taken for half a month, stool is formed once a day, the weight is increased, the face is ruddy, and the energy is vigorous.
Case 2:
consider a woman, age 53, a station cadre in Shanghai. The chronic atrophic gastritis has symptoms of stomachache and dyspepsia for years, the doctor still does not get better with imported drugs such as ranitidine, and the doctor takes the traditional Chinese medicine oral liquid in 8 th month in 94 years, so that the subjective pain disappears and people feel comfortable.
Case 3:
song Dynasty, women, age 70, in the third year. The oral liquid has the advantages of normal digestion function, no stomach pain for a long time, unobstructed stools, enhanced resistance and immunity, disappearance of the dry cough for many years, few colds, quick recovery of occasional colds, good appetite, good spirit and good sleep.
In conclusion, the traditional Chinese medicine oral liquid for eliminating gastrointestinal diseases provided by the invention has good clinical curative effect and no toxic or side effect, not only has the functions of resisting fatigue, improving human immunity and organism functions, but also can obviously reduce the use of antibiotics for gastrointestinal disease patients, and avoids toxic or side effect of western antibacterial drugs and injury brought by operation.
The foregoing shows and describes the general principles, principal features, and advantages of the invention. The present invention is not limited to the above embodiments, and the above embodiments and descriptions are only illustrative of the principle of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the present invention, and these changes and modifications are within the scope of the present invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (8)

1. The traditional Chinese medicine oral liquid is characterized by comprising the following components in parts by weight:
5-50 parts of pine pollen concentrated solution, 2-30 parts of gynostemma pentaphylla solution, 1-10 parts of hawthorn solution, 1-5 parts of pearl powder aqueous solution and 1-5 parts of medlar solution.
2. The traditional Chinese medicine oral liquid of claim 1, which is characterized in that: the pearl powder health-care beverage comprises, by weight, 50 parts of pine pollen concentrated solution, 30 parts of gynostemma pentaphylla solution, 10 parts of hawthorn solution, 5 parts of pearl powder aqueous solution and 5 parts of medlar solution.
3. The traditional Chinese medicine oral liquid according to claim 1 or 2, wherein the pine pollen in the pine pollen concentrated solution is refined Chinese red pine pollen.
4. A method for preparing the traditional Chinese medicine oral liquid according to any one of claims 1 to 3, which comprises the following steps:
a. preparing a pollen pini concentrated solution: drying pollen Pini, extracting to obtain nutrient solution, sequentially performing rough filtration, fine filtration, concentration, blending, bottling, sterilization, labeling, packaging, sampling inspection, and warehousing;
b. preparing gynostemma pentaphylla solution according to the proportion of 1: decocting with water at a ratio of 20, decocting for 2 hr, and pouring out the decoction according to the ratio of 1: adding water in a proportion of 20, boiling for 1 hour, pouring out the liquid, mixing the two liquids, boiling or concentrating, taking the concentrated liquid as 10 times of the raw material, filtering, pouring into a pot, sealing and putting into a cold storage for later use; respectively preparing the hawthorn juice and the medlar juice by the same method;
c. preparing a pearl powder aqueous solution, dissolving the instant pearl powder with purified water according to the proportion of 1;
d. mixing the prepared pollen Pini concentrated solution, herba Gynostemmatis solution, fructus crataegi solution, margarita powder water solution, and fructus Lycii solution, and stirring to obtain the Chinese medicinal oral liquid.
5. The method for preparing a Chinese medicinal oral liquid according to claim 4, wherein the method comprises the following steps: the sensory indexes of the pine pollen concentrated solution in the step a are as follows: (1) the appearance is light brown yellow translucent liquid; (2) has the unique flavor of the pine pollen and is sour, sweet and delicious; (3) the long-term storage at room temperature allows a small amount of precipitation and no peculiar smell.
6. The method for preparing a Chinese medicinal oral liquid according to claim 4, wherein the method comprises the following steps: the physical and chemical indexes of the pine pollen concentrated solution in the step a are as follows: (1) the sugar content is less than 50 percent; (2) the PH value is 4-4.5; (3) the plum degree of the concentrated solution is about 12 degrees Be; (4) the mg/Kg of lead (calculated by Pb) is less than or equal to 1; (5) arsenic (calculated As As) mg/Kg is less than or equal to 1.
7. The method for preparing a Chinese medicinal oral liquid according to claim 4, wherein the method comprises the following steps: the microorganism indexes of the pine pollen concentrated solution in the step a are as follows: (1) total number of colonies: (cfu/g) is less than or equal to 100; (2) coliform group bacteria: (MPN/100 g) is less than or equal to 30; (3) total number of molds: (cfu/g) is less than or equal to 10; (4) pathogenic bacteria: and cannot be detected.
8. The use of the Chinese medicinal oral liquid according to any one of claims 1 to 3 or the Chinese medicinal oral liquid according to any one of claims 4 to 7, which is prepared by the method for preparing the Chinese medicinal oral liquid, is characterized in that: can be used for treating gastrointestinal diseases.
CN202210746135.7A 2022-06-29 2022-06-29 Traditional Chinese medicine oral liquid and preparation method and application thereof Pending CN115192655A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1228943A (en) * 1998-03-13 1999-09-22 于林 Haw, pollen beverage and production method thereof
CN1308942A (en) * 2000-02-15 2001-08-22 蒲秀琴 Tea for beautifying face and lossing weight
CN1839965A (en) * 2006-01-25 2006-10-04 余内逊 Preparation method of stomach-tonifying food-digesting oral liquid containing micro pine pollen, fig,haw, chickens gizzard-membrane, 'houtou'mushroom etc.
CN1840020A (en) * 2006-01-25 2006-10-04 余内逊 Preparation method of liver-benefiting face-beautifying oral liquid with micron pine pollen and pearl powder for women
CN102246956A (en) * 2011-05-25 2011-11-23 郭景龙 Healthcare food containing pollen pini and preparation method thereof
CN104473249A (en) * 2014-11-23 2015-04-01 福州乾正药业有限公司 Pine pollen liquid preparation and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1228943A (en) * 1998-03-13 1999-09-22 于林 Haw, pollen beverage and production method thereof
CN1308942A (en) * 2000-02-15 2001-08-22 蒲秀琴 Tea for beautifying face and lossing weight
CN1839965A (en) * 2006-01-25 2006-10-04 余内逊 Preparation method of stomach-tonifying food-digesting oral liquid containing micro pine pollen, fig,haw, chickens gizzard-membrane, 'houtou'mushroom etc.
CN1840020A (en) * 2006-01-25 2006-10-04 余内逊 Preparation method of liver-benefiting face-beautifying oral liquid with micron pine pollen and pearl powder for women
CN102246956A (en) * 2011-05-25 2011-11-23 郭景龙 Healthcare food containing pollen pini and preparation method thereof
CN104473249A (en) * 2014-11-23 2015-04-01 福州乾正药业有限公司 Pine pollen liquid preparation and preparation method thereof

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