CN115120637A - Antibacterial and antiviral liquid medicine and preparation method thereof - Google Patents

Antibacterial and antiviral liquid medicine and preparation method thereof Download PDF

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CN115120637A
CN115120637A CN202210858266.4A CN202210858266A CN115120637A CN 115120637 A CN115120637 A CN 115120637A CN 202210858266 A CN202210858266 A CN 202210858266A CN 115120637 A CN115120637 A CN 115120637A
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李文邦
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Abstract

The application provides an antibacterial and antiviral liquid medicine, and relates to the technical field of traditional Chinese medicines. An antibacterial and antiviral liquid medicine comprises the following raw materials in parts by weight: 50-350 parts of hydrated lime, 1-6 parts of sulfur, 1-5 parts of realgar, 550 parts of eucalyptus leaves and 650 parts of blumea balsamifera. The application uses the hydrated lime to detoxify and corrode, disinfects and sterilizes the surface of the skin, removes rotten skin of the diseased part and promotes the recovery of ulcer; the added sulfur and the hydrated lime can play a role in synergy, and can promote the sterilization and disinfection effects on the skin surface; the added realgar can eliminate dampness, detoxify and kill parasites, thereby eliminating dampness and heat in the body and fundamentally treating skin diseases; the eucalyptus leaves are cool in nature and can disperse heat evil; blumea balsamifera is warm in nature and can soften the property of the liquid medicine. The hydrated lime, the sulfur, the realgar and the eucalyptus leaves are selected as raw materials, so that respective advantages can be exerted, and the hydrated lime, the sulfur, the realgar and the eucalyptus leaves are mutually cooperated, so that a remarkable treatment effect on skin diseases is achieved.

Description

Antibacterial and antiviral liquid medicine and preparation method thereof
Technical Field
The application relates to the technical field of traditional Chinese medicines, in particular to an antibacterial and antiviral liquid medicine and a preparation method thereof.
Background
Viruses are a class of pathogens that are smaller than bacteria, are widely distributed in nature, and can invade the human body through different routes to cause diseases. The pathological changes of the skin mucosa caused by viruses are called viral skin diseases. The virus has special preference for different tissues of a human body, so the types of viral skin diseases caused by the virus are various, and the common diseases comprise herpes simplex, herpes zoster, chicken pox, flat wart, verruca vulgaris, molluscum contagiosum, measles, rubella, herpangina, hand-foot-and-mouth disease and the like. In addition, bacteria also cause skin diseases. Various skin diseases caused by trichomonas vaginitis, colpitis mycotica, bacterial vaginosis, fungal and viral infection bring much pain to patients with skin diseases.
However, the skin diseases caused by the problems are not ideal in the treatment effect of the skin diseases, no matter Western medicines or traditional Chinese medicines which have many side effects and high cost. Therefore, a preparation having an excellent therapeutic effect on skin diseases is urgently required.
Disclosure of Invention
The purpose of the application is to provide an antibacterial and antiviral liquid medicine which has the advantage of excellent treatment effect on skin diseases caused by bacteria and viruses.
Another objective of the present application is to provide a method for preparing an antibacterial and antiviral drug solution, so as to obtain the antibacterial and antiviral drug solution.
The technical problem to be solved by the application is solved by adopting the following technical scheme.
On one hand, the embodiment of the application provides an antibacterial and antiviral liquid medicine, which comprises the following raw materials in parts by weight: 50-350 parts of hydrated lime, 1-6 parts of sulfur, 1-5 parts of realgar, 550 parts of eucalyptus leaves and 650 parts of blumea balsamifera.
On the other hand, the embodiment of the application provides a preparation method of an antibacterial and antiviral liquid medicine, which comprises the following steps:
crushing and mixing the raw materials except the hydrated lime to obtain a mixture;
adding 500-1500 parts by weight of water into the mixture, uniformly stirring, adding the mixture, heating, and filtering to obtain the antibacterial and antiviral liquid medicine. Compared with the prior art, the method has the advantages that,
slaked lime: pungent, warm in nature, toxic. Drying dampness, killing parasites, stopping bleeding, relieving pain and removing malignant flesh. It can be used for treating scabies, tinea, eczema, wound hemorrhage, scald, hemorrhoid, rectocele, and wart. Orally taken to stop diarrhea and dysentery, metrorrhagia and leukorrhagia.
Sulfur: sour, warm in nature, toxic. It enters kidney and large intestine meridians. Externally used for detoxifying, killing parasites and treating sore; it can tonify fire, strengthen yang and relieve constipation. It can be used for treating scabies, tinea pedis, carbuncle of yin type, and malignant boil; it is orally administered for treating impotence, cold foot, asthma, constipation.
Realgar: pungent, warm in nature, toxic. It enters liver and large intestine meridians. Detoxify and kill parasites, dry dampness and dispel phlegm, check malaria. Can be used for treating carbuncle, furuncle, snake and insect bite, abdominal pain due to parasitic infestation, epilepsy, and malaria.
Eucalyptus leaves: bitter and pungent taste and cool in nature. It can be used for treating common cold, influenza, dysentery, enteritis, arthralgia, cystitis, scald, scabies, erysipelas, neurodermatitis, eczema, carbuncle, sore, and toxic swelling.
Blumea balsamifera: pungent and bitter with warm nature. Warming the middle energizer, promoting blood circulation, expelling wind and removing dampness, and killing parasites. It is indicated for dysentery due to cold-dampness, abdominal pain, borborygmus, swelling, arthralgia and myalgia, traumatic injury, tinea and sore.
Phellodendron bark: bitter taste and cold nature. It enters kidney and bladder meridians. Clear heat and dry dampness, purge fire and remove heat, remove toxicity and cure sore. Can be used for treating dysentery due to damp-heat pathogen, jaundice, leukorrhagia, stranguria with heat pathogen, tinea pedis, flaccidity { exorcism }, hectic fever due to yin-deficiency, night sweat, spermatorrhea, pyocutaneous disease, toxic swelling, eczema, and pruritus. Salted cortex phellodendri is used for nourishing yin and reducing internal heat. Can be used for treating hyperactivity of fire due to yin deficiency, night sweat and steaming bone.
Rhizoma atractylodis: pungent and bitter with warm nature. It enters spleen, stomach and liver meridians. Dry dampness and invigorate spleen, dispel wind and cold, improve vision. Can be used for treating abdominal distention, diarrhea, edema, tinea pedis, paralysis 36484m, rheumatalgia, common cold due to wind-cold evil, and night blindness.
And (3) pseudolarix: pungent flavor and warm nature. Is toxic. Relieve itching and kill parasites. Can be used for treating tinea manuum, tinea pedis, neurodermatitis, eczema, and dysentery. Soaking cortex pseudolaricis or cortex pseudolaricis in Chinese liquor (cortex pseudolaricis tincture); or grinding into fine powder, mixing with vinegar, and applying to affected part.
Excess production: sour in taste and cool in nature. Induce diuresis to remove heat, activate blood and remove toxicity. It is indicated for edema, beriberi, sore, abscess, difficult urination and menstrual abdominal pain.
Polygonum hirsutum Thunb: pungent flavor and warm nature. Clearing away heat and toxic material, expelling pus and promoting granulation, promoting blood circulation and promoting eruption. It is mainly manifested as fever due to exogenous pathogenic factors, tonsillitis, chronic malaria, dysentery, diarrhea, carbuncle, cellulitis, fistula, scrofula, contusion, snake and insect bite, traumatic injury, rheumatalgia, measles without luring.
Duckweed: pungent flavor and cold in nature. It enters lung meridian. Disperse wind-heat, promote eruption and induce diuresis. Can be used for treating measles without adequate eruption, rubella with pruritus, edema, and oliguria.
The embodiment of the application has at least the following advantages or beneficial effects:
the inventors believe that the onset of skin disease is due to the following causes: pathogenic heat affecting the exterior, entering the interior to transform into heat, causing excessive heat in viscera, accumulating in the skin and failing to discharge, causing wind-heat to stagnate in the lung, and treating diseases due to fumigation, excessive toxic heat scorching the qi and blood and flaring out the exterior of the muscles; or wind pathogen entering into body, skin striae and skin striae, defensive qi is not firm, wind pathogen invades due to deficiency, and blocks skin, the interior cannot be communicated, the exterior cannot be discharged, nutrient-defensive qi is not harmonized, qi and blood circulation is abnormal, body resistance to virus and bacteria is weak, and skin damp-heat stagnation is caused by the inclined attack of virus and bacteria, and the skin disease is manifested as skin disease. Based on the above, the inventor of the application uses the hydrated lime to detoxify and erode, disinfects and sterilizes the surface of the skin, removes the decayed skin of the diseased part and promotes the recovery of the ulcer through creative work, and the hydrated lime contains calcium, can promote the contraction of capillary vessels and inhibit the guide overflow, thereby promoting the recovery of the wound surface; the added sulfur and the hydrated lime can play a role in synergy, can promote the sterilization and disinfection of the skin surface, has the killing effect on scabies, bacteria and fungi, and can remove grease, soften epidermis and dissolve cutin, thereby promoting the drug effect to permeate the skin; the added realgar can eliminate dampness, detoxify and kill parasites, thereby eliminating dampness and heat in the body and fundamentally treating skin diseases; the eucalyptus leaves are cool in nature, can disperse heat evil, clear away heat and toxic materials and clear up heat toxin of a body, and have excellent effects of removing dampness and clearing heat under the combined action of the eucalyptus leaves and the realgar; the blumea balsamifera is warm in nature, can soften the medicine property of the liquid medicine, and can warm the middle energizer and eliminate dampness, so that the medicine effect is enhanced. The hydrated lime, the sulfur, the realgar and the eucalyptus leaves are selected as raw materials, so that respective advantages can be exerted, and the hydrated lime, the sulfur, the realgar and the eucalyptus leaves are mutually cooperated, so that a remarkable treatment effect on skin diseases is achieved.
The preparation method is simple and convenient, and the antibacterial and antiviral liquid medicine can be quickly prepared.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that, in the present application, the embodiments and features of the embodiments may be combined with each other without conflict. The present application will be described in detail below with reference to specific examples.
The embodiment provides an antibacterial and antiviral liquid medicine which comprises the following raw materials in parts by weight: 50-350 parts of hydrated lime, 1-6 parts of sulfur, 1-5 parts of realgar, 550 parts of eucalyptus leaves and 650 parts of blumea balsamifera. The inventors believe that the onset of skin disease is due to the following causes: the heat is infected by the pathogenic heat and epidemic toxin, the heat is transformed into heat in the interior, the internal organs are excessive heat and stagnate in the skin, and the heat cannot escape, so that the wind-heat stagnates the lung, the patients are fumigated, the toxic heat is intense, and the heat burns qi and blood and externally erupts the superficial muscles; or wind pathogen entering into body, skin striae and skin striae, defensive qi is not firm, wind pathogen invades due to deficiency, and blocks skin, the interior cannot be communicated, the exterior cannot be discharged, nutrient-defensive qi is not harmonized, qi and blood circulation is abnormal, body resistance to virus and bacteria is weak, and skin damp-heat stagnation is caused by the inclined attack of virus and bacteria, and the skin disease is manifested as skin disease. Based on the above, through creative work, the inventor uses the hydrated lime to detoxify and corrode, disinfects and sterilizes the surface of the skin, removes rotten skin of the affected part, and promotes ulcer recovery, and the hydrated lime contains calcium, can promote capillary vasoconstriction, and inhibit carrying overflow, thereby promoting wound recovery; the added sulfur and the hydrated lime can play a role in synergy, can promote the sterilization and disinfection of the skin surface, has the killing effect on scabies, bacteria and fungi, and can remove grease, soften epidermis and dissolve cutin, thereby promoting the drug effect to permeate the skin; the added realgar can eliminate dampness, detoxify and kill parasites, thereby eliminating dampness and heat in the body and fundamentally treating skin diseases; the eucalyptus leaves are cool in nature, can disperse heat evil, clear away heat and toxic materials and clear up heat toxin of a body, and have excellent effects of removing dampness and clearing heat under the combined action of the eucalyptus leaves and the realgar; the blumea balsamifera is warm in nature, can soften the medicine property of the liquid medicine, and can warm the middle energizer and eliminate dampness, so that the medicine effect is enhanced. The hydrated lime, the sulfur, the realgar and the eucalyptus leaves are selected as raw materials, so that respective advantages can be exerted, and the hydrated lime, the sulfur, the realgar and the eucalyptus leaves are mutually cooperated, so that a remarkable treatment effect on skin diseases is achieved.
In some embodiments of the present application, the antibacterial and antiviral liquid medicine comprises the following raw materials in parts by weight: 100-300 parts of hydrated lime, 2-5 parts of sulfur, 1-3 parts of realgar, 500 parts of eucalyptus leaves and 600 parts of blumea balsamifera.
In some embodiments of the present application, the antibacterial and antiviral drug solution comprises the following raw materials in parts by weight: 200 parts of slaked lime, 4 parts of sulfur, 2 parts of realgar, 400 parts of eucalyptus leaves and 450 parts of blumea balsamifera.
In some embodiments of the present application, the antibacterial and antiviral liquid medicine further comprises the following raw materials in parts by weight: 10-20 parts of phellodendron, 5-15 parts of rhizoma atractylodis, 2-5 parts of cortex pseudolaricis, 2-8 parts of fructus Rosae Multiflorae, 5-10 parts of polygonum puberum and 10-20 parts of duckweed. The phellodendron bark, realgar, eucalyptus leaves and blumea balsamifera act together, so that the effects of clearing heat, eliminating dampness, reducing internal heat and detoxifying can be enhanced; the rhizoma atractylodis can enhance the effect of eliminating dampness; the pseudolarix is added, so that itching relieving, insect killing and bacteria killing can be realized; the addition of the nutritive ingredients can promote blood circulation to remove blood stasis, smooth qi and blood circulation and simultaneously play a role in detoxification; the polygonum puberum can clear away heat and toxic materials and enhance the efficacy of detoxification; the addition of the duckweed can disperse wind-heat, so that heat evil can be removed conveniently, and recovery of skin diseases is accelerated.
In some embodiments of the present application, the antibacterial and antiviral drug solution comprises the following raw materials in parts by weight: 300 parts of hydrated lime, 2-5 parts of sulfur, 1-3 parts of realgar, 500 parts of eucalyptus leaves, 600 parts of blumea balsamifera, 12-18 parts of phellodendron, 8-12 parts of rhizoma atractylodis, 2-4 parts of pseudolarix, 4-7 parts of fruit of Chinese flowering crab, 6-8 parts of polygonum puberum and 12-18 parts of duckweed.
In some embodiments of the present application, the antibacterial and antiviral liquid medicine comprises the following raw materials in parts by weight: 200 parts of slaked lime, 4 parts of sulfur, 2 parts of realgar, 400 parts of eucalyptus leaves, 450 parts of blumea balsamifera, 15 parts of golden cypress, 10 parts of rhizoma atractylodis, 3 parts of pseudolarix, 6 parts of Chinese gooseberry fruits, 7 parts of polygonum hydropiper and 15 parts of duckweed.
The embodiment also provides a preparation method of the antibacterial and antiviral liquid medicine, which comprises the following steps:
crushing and mixing the raw materials except the hydrated lime to obtain a mixture;
adding 500-1500 parts by weight of water into the mixture, uniformly stirring, adding the mixture, heating, and filtering to obtain the antibacterial and antiviral liquid medicine. The preparation method is simple and convenient, and the antibacterial and antiviral liquid medicine can be rapidly prepared.
In some embodiments of the present application, the above-mentioned mixture is crushed to a size of 30-80 mesh.
In some embodiments of the present application, the heating temperature is 95-115 ℃.
In some embodiments of the present application, the heat treatment time is 3 to 4 hours.
The features and properties of the present application are described in further detail below with reference to examples.
Example 1
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 50g of slaked lime, 1g of sulfur, 1g of realgar, 200g of eucalyptus leaves and 250g of blumea balsamifera.
Crushing the raw materials except the hydrated lime into 30 meshes, and mixing to obtain a mixture;
adding slaked lime into 500g of water, stirring, adding the mixture, heating at 95 ℃ for 3h, and filtering to obtain the antibacterial and antiviral liquid medicine.
Example 2
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 100g of slaked lime, 2g of sulfur, 1g of realgar, 250g of eucalyptus leaves and 300g of blumea balsamifera.
Crushing the raw materials except the hydrated lime into 50 meshes, and mixing to obtain a mixture;
adding slaked lime into 1000g of water, stirring, adding the mixture, heating at 100 deg.C for 3.5 hr, and filtering to obtain antibacterial and antiviral medicinal liquid.
Example 3
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 200g of slaked lime, 4g of sulfur, 2g of realgar, 400g of eucalyptus leaves and 450g of blumea balsamifera.
Crushing the raw materials except the hydrated lime to 50 meshes, and mixing to obtain a mixture;
adding slaked lime into 1000g of water, stirring, adding the mixture, heating at 95-115 deg.C for 3.5h, and filtering to obtain antibacterial and antiviral medicinal liquid.
Example 4
A preparation method of an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 300g of slaked lime, 5g of sulfur, 3g of realgar, 500g of eucalyptus leaves and 600g of blumea balsamifera.
Crushing the raw materials except the hydrated lime into 60 meshes, and mixing to obtain a mixture;
adding slaked lime into 1000g of water, stirring, adding the mixture, heating at 105 ℃ for 3.5h, and filtering to obtain the antibacterial and antiviral liquid medicine.
Example 5
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 350g of slaked lime, 6g of sulfur, 5g of realgar, 550g of eucalyptus leaves and 650g of blumea balsamifera.
Crushing the raw materials except the hydrated lime into 80 meshes, and mixing to obtain a mixture;
adding slaked lime into 1500g of water, stirring, adding the mixture, heating at 115 ℃ for 4h, and filtering to obtain the antibacterial and antiviral liquid medicine.
Example 6
This example is essentially the same as example 1, except that: also comprises cortex Phellodendri, rhizoma Atractylodis, cortex pseudolaricis, fructus Rosae Multiflorae, herba Polygoni Caespitosi and herba Spirodelae.
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 50g of slaked lime, 1g of sulfur, 1g of realgar, 200g of eucalyptus leaves, 250g of blumea balsamifera, 10g of golden cypress, 5g of rhizoma atractylodis, 2g of pseudolarix, 2g of fructus rosae rugosae, 5g of polygonum hydropiper and 10g of duckweed.
Crushing the raw materials except the hydrated lime into 30 meshes, and mixing to obtain a mixture;
adding slaked lime into 500g of water, stirring uniformly, adding the mixture, heating at 95 ℃ for 3h, and filtering to obtain the antibacterial and antiviral liquid medicine.
Example 7
This example is substantially the same as example 2, except that: also comprises cortex Phellodendri, rhizoma Atractylodis, cortex pseudolaricis, fructus Rosae Multiflorae, herba Polygoni Caespitosi and herba Spirodelae.
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 100g of slaked lime, 2g of sulfur, 1g of realgar, 250g of eucalyptus leaves, 300g of blumea balsamifera, 12g of golden cypress, 8g of rhizoma atractylodis, 2g of pseudolarix, 4g of Chinese gooseberry fruits, 6g of polygonum pubescens and 12g of duckweed.
Crushing the raw materials except the hydrated lime to 50 meshes, and mixing to obtain a mixture;
adding slaked lime into 1000g of water, stirring, adding the mixture, heating at 100 deg.C for 3.5 hr, and filtering to obtain antibacterial and antiviral medicinal liquid.
Example 8
This example is substantially the same as example 3, except that: also comprises cortex Phellodendri, rhizoma Atractylodis, cortex pseudolaricis, fructus Rosae Multiflorae, herba Polygoni Caespitosi and herba Spirodelae.
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 200g of slaked lime, 4g of sulfur, 2g of realgar, 400g of eucalyptus leaves, 450g of blumea balsamifera, 15g of golden cypress, 10g of rhizoma atractylodis, 3g of pseudolarix, 6g of Chinese gooseberry fruits, 7g of polygonum pubescens and 15g of duckweed.
Crushing the raw materials except the hydrated lime to 50 meshes, and mixing to obtain a mixture;
adding slaked lime into 1000g of water, stirring, adding the mixture, heating at 95-115 deg.C for 3.5h, and filtering to obtain antibacterial and antiviral medicinal liquid.
Example 9
This example is substantially the same as example 4, except that: also comprises cortex Phellodendri, rhizoma Atractylodis, cortex pseudolaricis, fructus Rosae Multiflorae, herba Polygoni Caespitosi and herba Spirodelae.
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 300g of slaked lime, 5g of sulfur, 3g of realgar, 500g of eucalyptus leaves, 600g of blumea balsamifera, 18g of golden cypress, 12g of rhizoma atractylodis, 4g of pseudolarix, 7g of Chinese gooseberry fruits, 8g of polygonum pubescens and 18g of duckweed.
Crushing the raw materials except the hydrated lime into 60 meshes, and mixing to obtain a mixture;
adding slaked lime into 1000g of water, stirring, adding the mixture, heating at 105 deg.C for 3.5 hr, and filtering to obtain antibacterial and antiviral medicinal liquid.
Example 10
This example is substantially the same as example 4, except that: also comprises cortex Phellodendri, rhizoma Atractylodis, cortex pseudolaricis, fructus Rosae Multiflorae, herba Polygoni Caespitosi and herba Spirodelae.
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 350g of slaked lime, 6g of sulfur, 5g of realgar, 550g of eucalyptus leaves, 650g of blumea balsamifera, 20g of golden cypress, 15g of rhizoma atractylodis, 5g of pseudolarix, 8g of Chinese gooseberry fruits, 10g of polygonum hydropiper and 20g of duckweed.
Crushing the raw materials except the hydrated lime into 80 meshes, and mixing to obtain a mixture;
adding slaked lime into 1500g of water, stirring, adding the mixture, heating at 115 ℃ for 4h, and filtering to obtain the antibacterial and antiviral liquid medicine.
Comparative example 1
This comparative example is essentially the same as example 3, except that: it does not contain blumea balsamifera.
A method for preparing an antibacterial and antiviral liquid medicine comprises the following steps:
raw materials: 200g of slaked lime, 4g of sulfur, 2g of realgar and 400g of eucalyptus leaves.
Crushing the raw materials except the hydrated lime to 50 meshes, and mixing to obtain a mixture;
adding slaked lime into 1000g of water, stirring, adding the mixture, heating at 95-115 deg.C for 3.5h, and filtering to obtain antibacterial and antiviral medicinal liquid.
Examples of the experiments
80 SD rats with 2-3 weeks of age are selected, the weight of each SD rat is half of that of each SD rat, the weight of each SD rat is 120-130g, the weight difference of the same test is not more than 10g, and the SD rats are bred adaptively for one week. The rats were divided into 4 groups at random, each group having the same number of males and females, and the rats were tested with the antibacterial and antiviral solutions prepared in examples 3 and 8 and comparative example 1, respectively, and with physiological saline.
Before the experiment, hairs on two sides of the back of the rat spine are removed by 8% sodium sulfide, the skin is rubbed by sterile sand paper to be in a bleeding state, the trichophyton rubrum stock solution is smeared to the hairless part of the rat, 1mL of the stock solution is smeared for 7 days continuously, the skin scraps at the inoculated part are scraped every day, and after the stock solution is softened by 10% potassium hydroxide, the hypha of the trichophyton rubrum is observed through microscopic examination, namely the molding success is achieved. The rats of each group were further smeared with the corresponding antibacterial and antiviral liquid medicine/physiological saline every morning and evening, 1mL of the liquid medicine/physiological saline was smeared each time, the skin of the inoculated part of each group of guinea pigs was scraped every other day after the administration and observed by microscopic examination, and the skin conditions of the rats 7 days after the administration were as shown in table 1.
Good recovery: the skin has no infection and scab.
The recovery is better: the skin is reddish and has no scab.
The recovery is general: the skin turns red and scabs are abundant.
Poor recovery: large skin damage, large area of nodular dandruff, scabbing, and local hair loss.
TABLE 1
Group of Good recovery/only Better/only recovery Resume normal/only Poor/only recovery
Example 3 10 5 4 1
Example 8 13 5 2 0
Comparative example 1 6 6 2 6
Physiological saline 0 2 8 10
By observing the table 1, the antibacterial and antiviral liquid medicine prepared by the application has a remarkable treatment effect on skin diseases, and by comparing the antibacterial and antiviral liquid medicine with the antibacterial and antiviral liquid medicine in the example 3 and the comparative example 1, the drug effect is greatly influenced due to the lack of the blumea balsamifera.
Typical cases are:
1. hongxx, male, 18 years old, suffered from acne for 4 years, the acne was developed on face and back, the acne was improved during the period of medication through the treatment of hospital and beauty salon and the nursing of Chinese medicine, however, the acne recurred after the medicine is stopped, the antibacterial and antiviral liquid medicine prepared in the embodiment 3 of the application is selected and used, the liquid medicine is coated on the acne part in the morning and evening every day, 2 weeks are a course of treatment, and after 2 courses of treatment, the medicine is stopped and the acne does not recur.
2. Paragraph xx, a woman, 2 years old and 3 months old, when a patient is in a doctor, the patient is heated for 2 days, the fever is treated based on the antipyretic antiviral drug, but after the fever is abated, the fever is regained, the herpes exists on the hands and the feet of the patient, the antipyretic drug and the antibacterial and antiviral drug solution prepared in the application example 7 are used, the drug solution is coated on the acne part in the morning and evening every day, after the fever abates, the antipyretic drug is stopped, the antibacterial and antiviral drug solution is continuously used for 3 days, and the patient is cured.
3. Zhaxx, female, 19 years old, more small blisters on hand skin and local red and swollen, selects the antibacterial and antiviral liquid medicine prepared in the application example 5, coats the liquid medicine on the acne part in the morning and evening every day, 2 weeks is a treatment course, and after 1 treatment course, the medicine is stopped and the acne is cured.
4. The antibacterial and antiviral liquid medicine prepared in the embodiment 2 is applied to the acne part every morning and evening, 2 weeks for one treatment course, and after 2 treatment courses, the medicine is stopped and the acne part is cured.
5. Paragraph xx, men and 30 years old have dense and numb small papules on the scalp, oval alopecia spots exist, and grayish white scales exist on the surface, the antibacterial and antiviral liquid medicine prepared by the application example 3 is applied to acne positions in the morning and evening every day, 2 weeks are a treatment course, and after 2 treatment courses, the medicine is stopped and the acne is cured.
6. Yellow xx, female, age 27, dry, reddish and raised facial skin, local blister, select the antibacterial and antiviral liquid medicine prepared in example 2, apply the liquid medicine to the acne part every morning and evening, 1 week later, stop medicine, recover.
In summary, the inventors of the present application believe that the onset of skin diseases is due to the following causes: the heat is infected by the pathogenic heat and epidemic toxin, the heat is transformed into heat in the interior, the internal organs are excessive heat and stagnate in the skin, and the heat cannot escape, so that the wind-heat stagnates the lung, the patients are fumigated, the toxic heat is intense, and the heat burns qi and blood and externally erupts the superficial muscles; or wind pathogen entering into body, skin striae and skin striae, defensive qi is not firm, wind pathogen invades due to deficiency, and blocks skin, the interior cannot be communicated, the exterior cannot be discharged, nutrient-defensive qi is not harmonized, qi and blood circulation is abnormal, body resistance to virus and bacteria is weak, and skin damp-heat stagnation is caused by the inclined attack of virus and bacteria, and the skin disease is manifested as skin disease. Based on the above, through creative work, the inventor uses the hydrated lime to detoxify and corrode, disinfects and sterilizes the surface of the skin, removes rotten skin of the affected part, and promotes ulcer recovery, and the hydrated lime contains calcium, can promote capillary vasoconstriction, and inhibit carrying overflow, thereby promoting wound recovery; the added sulfur and the hydrated lime can play a role in synergy, can promote the sterilization and disinfection of the skin surface, has the killing effect on scabies, bacteria and fungi, and can remove grease, soften epidermis and dissolve cutin, thereby promoting the drug effect to permeate the skin; the added realgar can eliminate dampness, detoxify and kill parasites, thereby eliminating dampness and heat in the body and fundamentally treating skin diseases; the eucalyptus leaves are cool in nature, can disperse heat evil, clear away heat and toxic materials and clear up heat toxin of a body, and have excellent effects of removing dampness and clearing heat under the combined action of the eucalyptus leaves and the realgar; the blumea balsamifera has warm property, can soften the medicine property of the liquid medicine, and can warm the middle and eliminate dampness, thereby enhancing the medicine effect. The hydrated lime, the sulfur, the realgar and the eucalyptus leaves are selected as raw materials, so that respective advantages can be exerted, and the hydrated lime, the sulfur, the realgar and the eucalyptus leaves are mutually cooperated, so that a remarkable treatment effect on skin diseases is achieved.
The preparation method is simple and convenient, and the antibacterial and antiviral liquid medicine can be quickly prepared.
The embodiments described above are some, but not all embodiments of the present application. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Claims (10)

1. The antibacterial and antiviral liquid medicine is characterized by comprising the following raw materials in parts by weight: 50-350 parts of hydrated lime, 1-6 parts of sulfur, 1-5 parts of realgar, 550 parts of eucalyptus leaves and 650 parts of blumea balsamifera.
2. The antibacterial and antiviral liquid medicine according to claim 1, characterized in that the antibacterial and antiviral liquid medicine comprises the following raw materials in parts by weight: 100 portions of hydrated lime, 2 to 5 portions of sulfur, 1 to 3 portions of realgar, 500 portions of eucalyptus leaves and 600 portions of blumea balsamifera.
3. The antibacterial and antiviral liquid medicine according to claim 1, characterized in that the antibacterial and antiviral liquid medicine comprises the following raw materials in parts by weight: 200 parts of slaked lime, 4 parts of sulfur, 2 parts of realgar, 400 parts of eucalyptus leaves and 450 parts of blumea balsamifera.
4. The antibacterial and antiviral liquid medicine according to any one of claims 1 to 3, characterized in that the antibacterial and antiviral liquid medicine further comprises the following raw materials in parts by weight: 10-20 parts of phellodendron, 5-15 parts of rhizoma atractylodis, 2-5 parts of cortex pseudolaricis, 2-8 parts of fructus Rosae Multiflorae, 5-10 parts of polygonum puberum and 10-20 parts of duckweed.
5. The antibacterial and antiviral liquid medicine according to claim 4, characterized in that the antibacterial and antiviral liquid medicine comprises the following raw materials in parts by weight: 300 parts of hydrated lime, 2-5 parts of sulfur, 1-3 parts of realgar, 500 parts of eucalyptus leaves, 600 parts of blumea balsamifera, 12-18 parts of phellodendron, 8-12 parts of rhizoma atractylodis, 2-4 parts of pseudolarix, 4-7 parts of fruit of Chinese flowering crab, 6-8 parts of polygonum puberum and 12-18 parts of duckweed.
6. The antibacterial and antiviral liquid medicine according to claim 5, characterized in that the antibacterial and antiviral liquid medicine comprises the following raw materials by weight: 200 parts of slaked lime, 4 parts of sulfur, 2 parts of realgar, 400 parts of eucalyptus leaves, 450 parts of blumea balsamifera, 15 parts of golden cypress, 10 parts of rhizoma atractylodis, 3 parts of pseudolarix, 6 parts of Chinese gooseberry fruits, 7 parts of polygonum hydropiper and 15 parts of duckweed.
7. The method for preparing an antibacterial and antiviral drug solution according to any one of claims 1 to 6, comprising the steps of:
crushing and mixing the raw materials except the hydrated lime to obtain a mixture;
adding 500-1500 parts by weight of water into the mixture, uniformly stirring, adding the mixture, heating, and filtering to obtain the antibacterial and antiviral liquid medicine.
8. The method for preparing an antibacterial and antiviral liquid medicine according to claim 7, wherein the size of the crushed mixture is 30-80 mesh.
9. The method for preparing an antibacterial and antiviral liquid medicine according to claim 7, wherein the heating temperature is 95-115 ℃.
10. The method for preparing an antibacterial and antiviral liquid medicine according to claim 7, wherein the heat treatment time is 3-4 h.
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102784340A (en) * 2012-08-09 2012-11-21 陈俊梅 Traditional Chinese medicine composition for treating children eczema
CN104147045A (en) * 2014-08-12 2014-11-19 朱金凤 Plaster for effective treatment of foot ulcer
CN104189182A (en) * 2014-07-26 2014-12-10 杨建平 Traditional Chinese medicine lotion used for treating beriberi
CN104403843A (en) * 2014-11-24 2015-03-11 张彬 Handmade soap and preparation method thereof
CN108434233A (en) * 2018-06-07 2018-08-24 安徽老孙头鞋业有限公司 A kind of Chinese medicine composition for preventing tinea pedis, the ringworm of the foot, pin sweat
CN111514257A (en) * 2020-05-18 2020-08-11 蔡建华 Itching-relieving traditional Chinese medicine formula for insect bite dermatitis and preparation method thereof
CN112773835A (en) * 2021-03-12 2021-05-11 周梅玉 Ointment for treating various skin diseases

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102784340A (en) * 2012-08-09 2012-11-21 陈俊梅 Traditional Chinese medicine composition for treating children eczema
CN104189182A (en) * 2014-07-26 2014-12-10 杨建平 Traditional Chinese medicine lotion used for treating beriberi
CN104147045A (en) * 2014-08-12 2014-11-19 朱金凤 Plaster for effective treatment of foot ulcer
CN104403843A (en) * 2014-11-24 2015-03-11 张彬 Handmade soap and preparation method thereof
CN108434233A (en) * 2018-06-07 2018-08-24 安徽老孙头鞋业有限公司 A kind of Chinese medicine composition for preventing tinea pedis, the ringworm of the foot, pin sweat
CN111514257A (en) * 2020-05-18 2020-08-11 蔡建华 Itching-relieving traditional Chinese medicine formula for insect bite dermatitis and preparation method thereof
CN112773835A (en) * 2021-03-12 2021-05-11 周梅玉 Ointment for treating various skin diseases

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
唐庆恩等: "中药浸洗法治疗急性湿疹、手足癣56例", 上海中医药杂志, no. 11, pages 23 *
李诗梅译: "中药对放射线皮肤损害有保护作用", 中成药, vol. 13, no. 5, pages 43 *
赖志才等: "桉叶水提取物体外抗单纯疱疹病毒 I 型活性的实验研究", 中国名族民间医药, vol. 18, no. 20, pages 7 *
郝小燕等: "黔产艾纳香挥发油化学成分研究", 贵阳医学院学报, vol. 25, no. 2, pages 121 *

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