CN115087744A - 用于无细胞MeDIP测序的合成加标对照及其使用方法 - Google Patents
用于无细胞MeDIP测序的合成加标对照及其使用方法 Download PDFInfo
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- CN115087744A CN115087744A CN202080092232.8A CN202080092232A CN115087744A CN 115087744 A CN115087744 A CN 115087744A CN 202080092232 A CN202080092232 A CN 202080092232A CN 115087744 A CN115087744 A CN 115087744A
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962931411P | 2019-11-06 | 2019-11-06 | |
| US62/931,411 | 2019-11-06 | ||
| PCT/CA2020/051507 WO2021087615A1 (en) | 2019-11-06 | 2020-11-06 | Synthetic spike-in controls for cell-free medip sequencing and methods of using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115087744A true CN115087744A (zh) | 2022-09-20 |
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ID=75849048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080092232.8A Pending CN115087744A (zh) | 2019-11-06 | 2020-11-06 | 用于无细胞MeDIP测序的合成加标对照及其使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230024827A1 (https=) |
| EP (2) | EP4435118A3 (https=) |
| JP (1) | JP2023502018A (https=) |
| KR (1) | KR20220098183A (https=) |
| CN (1) | CN115087744A (https=) |
| BR (1) | BR112022008714A2 (https=) |
| CA (1) | CA3157323A1 (https=) |
| GB (1) | GB2609715B (https=) |
| WO (1) | WO2021087615A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111154846A (zh) * | 2020-01-13 | 2020-05-15 | 四川大学华西医院 | 一种甲基化核酸的检测方法 |
| US12592321B2 (en) | 2020-06-19 | 2026-03-31 | University Health Network | Cancer detection and classification using methylome analysis |
| CN114045342A (zh) * | 2021-12-01 | 2022-02-15 | 大连晶泰生物技术有限公司 | 一种游离DNA(cfDNA)甲基化突变的检测方法及试剂盒 |
| KR20250019610A (ko) * | 2022-03-21 | 2025-02-10 | 빌리언투원, 인크. | 치료 모니터링을 위한 메틸화된 세포 유리 dna의 분자 계수 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150132754A1 (en) * | 2012-05-14 | 2015-05-14 | Cb Biotechnologies, Inc. | Method for increasing accuracy in quantitative detection of polynucleotides |
| CN109415763A (zh) * | 2016-05-03 | 2019-03-01 | 大学健康网络 | 捕获无细胞的甲基化dna的方法及其用途 |
| CN109642227A (zh) * | 2016-07-19 | 2019-04-16 | 精密科学发展有限责任公司 | 来自非人类生物体的核酸对照分子 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3022321B1 (en) * | 2013-07-16 | 2021-01-13 | Zymo Research Corporation | Mirror bisulfite analysis |
| EP3978627A1 (en) * | 2016-03-25 | 2022-04-06 | Karius, Inc. | Methods using synthetic nucleic acid spike-ins |
| BR112020000681A2 (pt) * | 2017-07-12 | 2020-07-14 | University Health Network | detecção e classificação de cancro utilizando análise de metilome |
| CN111094583A (zh) * | 2017-08-04 | 2020-05-01 | 十亿至一公司 | 与生物靶相关的定量中利用靶相关分子的测序输出确定和分析 |
| US20210156863A1 (en) * | 2017-11-03 | 2021-05-27 | University Health Network | Cancer detection, classification, prognostication, therapy prediction and therapy monitoring using methylome analysis |
| NZ765943A (en) * | 2018-01-08 | 2022-10-28 | Ludwig Inst For Cancer Res Ltd | Bisulfite-free, base-resolution identification of cytosine modifications |
-
2020
- 2020-11-06 CN CN202080092232.8A patent/CN115087744A/zh active Pending
- 2020-11-06 KR KR1020227018998A patent/KR20220098183A/ko active Pending
- 2020-11-06 JP JP2022526702A patent/JP2023502018A/ja active Pending
- 2020-11-06 GB GB2207732.5A patent/GB2609715B/en active Active
- 2020-11-06 EP EP24177800.0A patent/EP4435118A3/en active Pending
- 2020-11-06 EP EP20884272.4A patent/EP4055183A4/en not_active Withdrawn
- 2020-11-06 WO PCT/CA2020/051507 patent/WO2021087615A1/en not_active Ceased
- 2020-11-06 CA CA3157323A patent/CA3157323A1/en active Pending
- 2020-11-06 BR BR112022008714A patent/BR112022008714A2/pt unknown
-
2022
- 2022-05-04 US US17/736,570 patent/US20230024827A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150132754A1 (en) * | 2012-05-14 | 2015-05-14 | Cb Biotechnologies, Inc. | Method for increasing accuracy in quantitative detection of polynucleotides |
| CN109415763A (zh) * | 2016-05-03 | 2019-03-01 | 大学健康网络 | 捕获无细胞的甲基化dna的方法及其用途 |
| CN109642227A (zh) * | 2016-07-19 | 2019-04-16 | 精密科学发展有限责任公司 | 来自非人类生物体的核酸对照分子 |
Non-Patent Citations (2)
| Title |
|---|
| KAIFU CHEN等: ""The Overlooked Fact: Fundamental Need for Spike-In Control for Virtually All Genome-Wide Analyses"", 《MOLECULAR AND CELLULAR BIOLOGY》, 31 March 2016 (2016-03-31), pages 662 - 667, XP055687658, DOI: 10.1128/MCB.00970-14 * |
| LICHUN JIANG等: ""Synthetic spike-in standards for RNA-seq experiments"", 《GENOME RESEARCH》, 30 September 2011 (2011-09-30), pages 1543 - 1551, XP055152443, DOI: 10.1101/gr.121095.111 * |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2609715A (en) | 2023-02-15 |
| GB202207732D0 (en) | 2022-07-13 |
| US20230024827A1 (en) | 2023-01-26 |
| EP4055183A1 (en) | 2022-09-14 |
| BR112022008714A2 (pt) | 2022-07-19 |
| WO2021087615A1 (en) | 2021-05-14 |
| JP2023502018A (ja) | 2023-01-20 |
| EP4055183A4 (en) | 2023-12-06 |
| EP4435118A3 (en) | 2025-01-15 |
| EP4435118A2 (en) | 2024-09-25 |
| CA3157323A1 (en) | 2021-05-14 |
| KR20220098183A (ko) | 2022-07-11 |
| GB2609715B (en) | 2025-07-30 |
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