CN115004076A - 无透镜显微成像系统、方法及生化物质检测系统、方法 - Google Patents
无透镜显微成像系统、方法及生化物质检测系统、方法 Download PDFInfo
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- CN115004076A CN115004076A CN202080094159.8A CN202080094159A CN115004076A CN 115004076 A CN115004076 A CN 115004076A CN 202080094159 A CN202080094159 A CN 202080094159A CN 115004076 A CN115004076 A CN 115004076A
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Images
Classifications
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/361—Optical details, e.g. image relay to the camera or image sensor
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
- G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
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- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/04—Processes or apparatus for producing holograms
- G03H1/0443—Digital holography, i.e. recording holograms with digital recording means
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/20—Filters
- G02B5/28—Interference filters
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- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/0005—Adaptation of holography to specific applications
- G03H2001/005—Adaptation of holography to specific applications in microscopy, e.g. digital holographic microscope [DHM]
Abstract
一种无透镜显微成像系统(11)，用于对具有图形编码的微珠(15)成像，包括照明系统(11a)与成像系统(11b)，照明系统(11a)包括照明光源(111)与激发光源(112)；成像系统(11b)包括图像传感器(113)；照明光源(111)用于发出照明光照射微珠(15)，使其投影至图像传感器(113)上成像；激发光源(112)用于发出激发光激发微珠(15)使微珠(15)发出特定信号，图像传感器(113)用于采集微珠(15)及特定信号的影像以生成图像，成像系统(11)内未设置透镜系统。提升微珠(15)检测效率。
Description
PCT国内申请，说明书已公开。
Claims (22)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2020/083738 WO2021203291A1 (zh) | 2020-04-08 | 2020-04-08 | 无透镜显微成像系统、方法及生化物质检测系统、方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115004076A true CN115004076A (zh) | 2022-09-02 |
Family
ID=78022666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080094159.8A Pending CN115004076A (zh) | 2020-04-08 | 2020-04-08 | 无透镜显微成像系统、方法及生化物质检测系统、方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20230124060A1 (zh) |
| EP (1) | EP4134725A4 (zh) |
| CN (1) | CN115004076A (zh) |
| WO (1) | WO2021203291A1 (zh) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101809444A (zh) * | 2007-08-08 | 2010-08-18 | 麦克斯韦尔传感器有限公司 | 数字磁珠分析的装置和方法 |
| CN102224410A (zh) * | 2008-09-24 | 2011-10-19 | 施特劳斯控股公司 | 用于测试分析物的成像分析仪 |
| CN102508356A (zh) * | 2011-09-30 | 2012-06-20 | 浙江大学 | 基于光学投影的无透镜显微成像方法及其装置 |
| CN109001900A (zh) * | 2018-09-05 | 2018-12-14 | 南京大学 | 一种明场和荧光双模态的显微成像系统及方法 |
| CN109884018A (zh) * | 2019-03-22 | 2019-06-14 | 华中科技大学 | 一种基于神经网络的亚微米级无透镜显微成像方法及系统 |
| US20190380585A1 (en) * | 2017-02-10 | 2019-12-19 | Peking University | Femtosecond pulse laser modulator and miniature two-photon microscopic imaging device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003139773A (ja) * | 2001-10-31 | 2003-05-14 | Ebara Corp | アフィニティー反応プローブビーズ及び検出システム |
| CN108362651B (zh) * | 2018-01-26 | 2021-07-16 | 绍兴柯桥睿宇光电科技有限公司 | 一种便携式无透镜多光谱显微成像系统和方法 |
| CN109112176A (zh) * | 2018-09-04 | 2019-01-01 | 武汉尚码生物科技有限公司 | 一种微球编码载体及其应用 |
-
2020
- 2020-04-08 EP EP20930394.0A patent/EP4134725A4/en active Pending
- 2020-04-08 WO PCT/CN2020/083738 patent/WO2021203291A1/zh unknown
- 2020-04-08 CN CN202080094159.8A patent/CN115004076A/zh active Pending
- 2020-04-08 US US17/913,958 patent/US20230124060A1/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101809444A (zh) * | 2007-08-08 | 2010-08-18 | 麦克斯韦尔传感器有限公司 | 数字磁珠分析的装置和方法 |
| CN102224410A (zh) * | 2008-09-24 | 2011-10-19 | 施特劳斯控股公司 | 用于测试分析物的成像分析仪 |
| CN102508356A (zh) * | 2011-09-30 | 2012-06-20 | 浙江大学 | 基于光学投影的无透镜显微成像方法及其装置 |
| US20190380585A1 (en) * | 2017-02-10 | 2019-12-19 | Peking University | Femtosecond pulse laser modulator and miniature two-photon microscopic imaging device |
| CN109001900A (zh) * | 2018-09-05 | 2018-12-14 | 南京大学 | 一种明场和荧光双模态的显微成像系统及方法 |
| CN109884018A (zh) * | 2019-03-22 | 2019-06-14 | 华中科技大学 | 一种基于神经网络的亚微米级无透镜显微成像方法及系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20230124060A1 (en) | 2023-04-20 |
| EP4134725A1 (en) | 2023-02-15 |
| EP4134725A4 (en) | 2024-01-03 |
| WO2021203291A1 (zh) | 2021-10-14 |
| JP2023519423A (ja) | 2023-05-10 |
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