CN114938804A - Menthol-based mosquito repellent liquid composition and preparation method thereof - Google Patents
Menthol-based mosquito repellent liquid composition and preparation method thereof Download PDFInfo
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- CN114938804A CN114938804A CN202210682339.9A CN202210682339A CN114938804A CN 114938804 A CN114938804 A CN 114938804A CN 202210682339 A CN202210682339 A CN 202210682339A CN 114938804 A CN114938804 A CN 114938804A
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- menthol
- mosquito repellent
- repellent liquid
- liquid composition
- based mosquito
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- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 title claims abstract description 97
- 229940041616 menthol Drugs 0.000 title claims abstract description 97
- 239000000077 insect repellent Substances 0.000 title claims abstract description 75
- 239000000203 mixture Substances 0.000 title claims abstract description 64
- 239000007788 liquid Substances 0.000 title claims abstract description 32
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 title claims abstract 20
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 51
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 29
- 239000000654 additive Substances 0.000 claims abstract description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 230000000996 additive effect Effects 0.000 claims abstract description 12
- 238000002485 combustion reaction Methods 0.000 claims abstract description 12
- 235000006679 Mentha X verticillata Nutrition 0.000 claims description 26
- 235000002899 Mentha suaveolens Nutrition 0.000 claims description 26
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims description 26
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 20
- 238000000855 fermentation Methods 0.000 claims description 12
- 230000004151 fermentation Effects 0.000 claims description 12
- KDSNLYIMUZNERS-UHFFFAOYSA-N 2-methylpropanamine Chemical compound CC(C)CN KDSNLYIMUZNERS-UHFFFAOYSA-N 0.000 claims description 10
- BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 claims description 10
- 239000006184 cosolvent Substances 0.000 claims description 10
- 239000002270 dispersing agent Substances 0.000 claims description 10
- 238000004821 distillation Methods 0.000 claims description 10
- 239000003995 emulsifying agent Substances 0.000 claims description 10
- 239000003381 stabilizer Substances 0.000 claims description 10
- NUMQCACRALPSHD-UHFFFAOYSA-N tert-butyl ethyl ether Chemical compound CCOC(C)(C)C NUMQCACRALPSHD-UHFFFAOYSA-N 0.000 claims description 10
- 244000025254 Cannabis sativa Species 0.000 claims description 9
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 claims description 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 6
- BPIUIOXAFBGMNB-UHFFFAOYSA-N 1-hexoxyhexane Chemical compound CCCCCCOCCCCCC BPIUIOXAFBGMNB-UHFFFAOYSA-N 0.000 claims description 5
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 5
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 claims description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 4
- 239000001593 sorbitan monooleate Substances 0.000 claims description 4
- 235000011069 sorbitan monooleate Nutrition 0.000 claims description 4
- 229940035049 sorbitan monooleate Drugs 0.000 claims description 4
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims description 3
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims description 3
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims description 3
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims description 3
- 239000005642 Oleic acid Substances 0.000 claims description 3
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims description 3
- 229960004050 aminobenzoic acid Drugs 0.000 claims description 3
- 239000004202 carbamide Substances 0.000 claims description 3
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims description 3
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims description 3
- -1 sucrose fatty acid ester Chemical class 0.000 claims description 3
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims description 2
- 229930006000 Sucrose Natural products 0.000 claims description 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 2
- 229930195729 fatty acid Natural products 0.000 claims description 2
- 239000000194 fatty acid Substances 0.000 claims description 2
- 229940083466 soybean lecithin Drugs 0.000 claims description 2
- 239000005720 sucrose Substances 0.000 claims description 2
- 229960004793 sucrose Drugs 0.000 claims description 2
- 241000255925 Diptera Species 0.000 abstract description 24
- 230000001846 repelling effect Effects 0.000 abstract description 12
- 239000003205 fragrance Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 241000282414 Homo sapiens Species 0.000 abstract description 4
- 241000238631 Hexapoda Species 0.000 abstract description 3
- 241001674044 Blattodea Species 0.000 abstract description 2
- 239000002360 explosive Substances 0.000 abstract description 2
- 231100000252 nontoxic Toxicity 0.000 abstract description 2
- 230000003000 nontoxic effect Effects 0.000 abstract description 2
- 231100000419 toxicity Toxicity 0.000 abstract description 2
- 230000001988 toxicity Effects 0.000 abstract description 2
- NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 description 78
- 238000000034 method Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 238000002156 mixing Methods 0.000 description 4
- 206010003399 Arthropod bite Diseases 0.000 description 3
- 244000246386 Mentha pulegium Species 0.000 description 3
- 235000016257 Mentha pulegium Nutrition 0.000 description 3
- 235000004357 Mentha x piperita Nutrition 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 235000001050 hortel pimenta Nutrition 0.000 description 3
- 239000000575 pesticide Substances 0.000 description 3
- 206010061217 Infestation Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- PZNPLUBHRSSFHT-RRHRGVEJSA-N 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCCCCCCCCCC PZNPLUBHRSSFHT-RRHRGVEJSA-N 0.000 description 1
- 208000001490 Dengue Diseases 0.000 description 1
- 206010012310 Dengue fever Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010014596 Encephalitis Japanese B Diseases 0.000 description 1
- 201000006353 Filariasis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 201000005807 Japanese encephalitis Diseases 0.000 description 1
- 241000710842 Japanese encephalitis virus Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 240000004460 Tanacetum coccineum Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000003152 Yellow Fever Diseases 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- ROVGZAWFACYCSP-MQBLHHJJSA-N [2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC1C(C)=C(C\C=C/C=C)C(=O)C1 ROVGZAWFACYCSP-MQBLHHJJSA-N 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000001442 anti-mosquito Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 208000025729 dengue disease Diseases 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 231100001231 less toxic Toxicity 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- 229940015367 pyrethrum Drugs 0.000 description 1
- UQDJGEHQDNVPGU-UHFFFAOYSA-N serine phosphoethanolamine Chemical compound [NH3+]CCOP([O-])(=O)OCC([NH3+])C([O-])=O UQDJGEHQDNVPGU-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000008347 soybean phospholipid Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/06—Oxygen or sulfur directly attached to a cycloaliphatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P17/00—Pest repellants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a menthol-based mosquito repellent liquid composition and a preparation method thereof, belonging to the technical field of mosquito repellent liquid and a preparation method thereof, wherein the composition comprises methanol, menthol, an ethanol additive and water, the components are environment-friendly, the mosquito repellent liquid composition contains a light fragrance suitable for people to smell, the menthol is uniformly volatilized by combustion according to the characteristic of easy volatilization of the menthol, the light fragrance is emitted, safe, nontoxic and harmless mosquito repelling can be carried out, and the formula system of the composition is reasonable in proportion, is inflammable and non-explosive, is free from leakage and toxicity, is harmless to human bodies, has an effect of repelling insects such as flies, mosquitoes, cockroaches and the like, and is suitable for families.
Description
Technical Field
The invention relates to the technical field of mosquito repellent liquid and a preparation method thereof, and particularly relates to a menthol-based mosquito repellent liquid composition and a preparation method thereof.
Background
Mosquitoes are insects which are widely distributed on the earth, and exist in all continents except Antarctica. Mosquitoes are one of four pests, not only have strong fecundity, but also have a plurality of varieties, more than 3000 varieties, and the larger harm of the mosquitoes is also the universality of diseases transmitted by the mosquitoes; in summer, not only can dermatitis, pruritus and swelling pain be caused by mosquito bites, and sleep is affected, but also some people may cause severe allergic reactions. Moreover, it can also transmit various diseases, such as disability and death caused by dengue fever, malaria, yellow fever, filariasis, Japanese encephalitis, etc. caused by mosquito bites. Therefore, the essence of mosquito repelling is to repel and prevent diseases.
Menthol, also called menthol, isA terpenoid organic compound with chemical formula of C 10 H 20 And O. Menthol is extracted from the leaves and stems of peppermint, is white crystals, and is the main component of peppermint and peppermint essential oils. Menthol generally has two isomers (D-form and L-form), natural menthol is mainly levorotatory isomer (L-menthol), and menthol is used as an aromatizer for toothpaste, perfume, beverage, candy, etc. It can be used as irritant in medicine, and has effects of refreshing and relieving itching. The oral administration can be used as a wind-expelling medicine for treating headache, inflammation of nose, pharynx, larynx and the like, and the application and mosquito expelling of the oral preparation are not reported temporarily.
In order to combat mosquito infestations and infestations, there are mainly 2 approaches: the first is a physical anti-mosquito method, such as screen doors, screen windows, mosquito nets, trousers and the like; the other is a chemical mosquito repelling method with pesticide, which has the mosquito repelling principle that the pesticide directly acts on the touch and chemical sensors of the mosquito to repel or kill the mosquito. Due to the limited effect of physical mosquito-repellent methods, with the development of society and the progress of science and technology, various chemical mosquito-repellent methods and products come into play, such as mosquito coil incense, electric mosquito repellent tablet, aerosol mosquito-repellent agent, toilet water, mosquito-repellent cream, mosquito-repellent agent, heating mosquito-repellent liquid and the like. Although these mosquito repelling products or methods make a great contribution to effectively preventing mosquito bites for human beings, most of them achieve the mosquito repelling effect by using toxic pyrethrum, deet, anophelifuge ester pesticides or chemical substances, are liquid or solid, are more or less toxic, and cause injury or discomfort to human bodies after long-term use.
Disclosure of Invention
In order to solve the above problems, embodiments of the present invention provide a mosquito repellent composition based on menthol and a preparation method thereof, and the present invention includes:
the invention provides a menthol-based mosquito repellent liquid composition which is technically characterized by comprising, by weight, 60-80 parts of methanol, 4-6 parts of menthol, 2-3 parts of ethanol, 2-3 parts of an additive and 10-30 parts of water.
Preferably, the menthol-based mosquito repellent composition of the present invention has a purity of 99.99% by volume of methanol.
Preferably, the preparation method of menthol in the menthol-based mosquito repellent composition comprises the following steps:
step 1: squeezing to obtain juice: selecting moldy mint, removing stems of the mint, and squeezing the mint to obtain mint juice;
step 2: and (3) low-temperature fermentation: inoculating yeast into the mint grass juice obtained in the step 1 according to the specification of 150-250mg/L, then performing temperature-controlled fermentation at the temperature of 18-20 ℃, and after fermentation, reducing the temperature to 2-5 ℃ for low-temperature storage;
and 3, step 3: and (3) distilling the mint grass juice fermented in the step (2) in a distillation device at the distillation temperature of 90-95 ℃, and collecting distillate to obtain the menthol.
Preferably, the additives in the menthol-based mosquito repellent composition of the present invention include an emulsifier, a stabilizer, a cosolvent, a combustion improver and a dispersant.
Preferably, the emulsifier in the menthol-based mosquito repellent composition of the present invention is at least one of sorbitan monooleate, soybean lecithin and sucrose fatty acid ester.
Preferably, the stabilizing agent in the menthol-based mosquito repellent composition of the present invention comprises di-tert-butyl-p-cresol and isobutylamine in a weight ratio of 3: 5.
Preferably, the cosolvent in the menthol-based mosquito repellent liquid composition of the present invention is at least one of oleic acid, p-aminobenzoic acid and urea.
Preferably, the combustion improver in the menthol-based mosquito repellent composition of the present invention comprises hexyl ether, methyl tert-butyl ether and ethyl tert-butyl ether in a weight ratio of 2:3: 5.
Preferably, the dispersing agent in the menthol-based mosquito repellent composition of the present invention is at least one of azomethylpyrrolidone, N-dimethylacetamide and N, N-dimethylformyl.
The invention also provides a preparation method of the menthol-based mosquito repellent liquid composition, which is technically characterized in that the menthol-based mosquito repellent liquid is obtained by uniformly mixing methanol, menthol, ethanol, an additive and water in proportion.
Compared with the prior art, the menthol-based mosquito repellent composition and the preparation method thereof can achieve the following technical effects:
the invention relates to a menthol-based mosquito repellent liquid composition which comprises methanol, menthol, an ethanol additive and water, wherein the components of the menthol-based mosquito repellent liquid composition are environment-friendly, the mosquito repellent liquid composition contains light fragrance suitable for people to smell, the menthol is uniformly volatilized through combustion according to the characteristic of easy volatilization of the menthol, the light fragrance is emitted, safe, nontoxic and harmless mosquito repelling can be carried out, and the formula system of the menthol-based mosquito repellent liquid composition is reasonable in proportion, is inflammable and non-explosive, is free from leakage and toxicity and harm to human bodies, has an effect of repelling insects such as flies, mosquitoes, cockroaches and the like, and is suitable for household use.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below with reference to the specific embodiments of the present invention. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A mosquito repellent liquid composition based on menthol comprises 70kg of methanol, 5kg of menthol, 2.5kg of ethanol, 2.5kg of additive and 20kg of water.
Preferably, the menthol-based mosquito repellent composition of the present invention has a purity of 99.99% by volume of methanol.
Preferably, the preparation method of menthol in the menthol-based mosquito repellent composition comprises the following steps:
step 1: squeezing to obtain juice: selecting moldless mint, removing stems, and squeezing the mint to obtain mint juice;
step 2: low-temperature fermentation: inoculating yeast into the mint herb juice obtained in the step 1 according to the specification of 200mg/L, fermenting at the controlled temperature of 19 ℃, and cooling to 3 ℃ after fermentation for low-temperature storage;
and step 3: and (3) distilling the mint grass juice fermented in the step (2) in a distillation device at the distillation temperature of 92.5 ℃, and collecting distillate to obtain the menthol.
Preferably, the additives in the menthol-based mosquito repellent composition of the present invention include an emulsifier, a stabilizer, a cosolvent, a combustion improver and a dispersant.
Preferably, the emulsifier in the menthol-based mosquito repellent composition of the present invention is sorbitan monooleate.
Preferably, the stabilizing agent in the menthol-based mosquito repellent composition of the present invention comprises di-tert-butyl-p-cresol and isobutylamine in a weight ratio of 3: 5.
Preferably, the cosolvent in the menthol-based mosquito repellent composition of the present invention is oleic acid.
Preferably, the combustion improver in the menthol-based mosquito repellent composition of the present invention comprises hexyl ether, methyl tert-butyl ether and ethyl tert-butyl ether in a weight ratio of 2:3: 5.
Preferably, the dispersant in the menthol-based mosquito repellent composition of the present invention is azomethylpyrrolidone.
According to the formula, the preparation method of the menthol-based mosquito repellent composition comprises the following steps: and uniformly mixing methanol, menthol, ethanol, an additive and water according to a proportion to obtain the menthol-based mosquito repellent liquid.
Example 2
A menthol-based mosquito repellent composition comprises 60kg of methanol, 4kg of menthol, 2kg of ethanol, 2kg of additive and 10kg of water.
Preferably, the menthol-based mosquito repellent composition of the present invention has a purity of 99.99% by volume of methanol.
Preferably, the preparation method of the menthol in the menthol-based mosquito repellent liquid composition comprises the following steps:
step 1: squeezing to obtain juice: selecting moldless mint, removing stems, and squeezing the mint to obtain mint juice;
step 2: low-temperature fermentation: inoculating microzyme into the mint grass juice obtained in the step 1 according to the specification of 150mg/L, fermenting at the controlled temperature of 18 ℃, and cooling to 2 ℃ after fermentation for low-temperature storage;
and step 3: and (3) distilling the mint grass juice fermented in the step (2) in a distillation device at the distillation temperature of 90 ℃, and collecting distillate to obtain the menthol.
Preferably, the additives in the menthol-based mosquito repellent composition of the present invention include an emulsifier, a stabilizer, a cosolvent, a combustion improver and a dispersant.
Preferably, the emulsifier in the menthol-based mosquito repellent composition of the present invention is sorbitan monooleate.
Preferably, the stabilizing agent in the menthol-based mosquito repellent composition of the present invention comprises di-tert-butyl-p-cresol and isobutylamine in a weight ratio of 3: 5.
Preferably, the cosolvent in the menthol-based mosquito repellent composition of the present invention is p-aminobenzoic acid.
Preferably, the combustion improver in the menthol-based mosquito repellent composition of the present invention comprises hexyl ether, methyl tert-butyl ether and ethyl tert-butyl ether in a weight ratio of 2:3: 5.
Preferably, the dispersing agent in the menthol-based mosquito repellent composition is N, N-dimethylacetamide.
According to the formula, the preparation method of the menthol-based mosquito repellent composition comprises the following steps: and uniformly mixing methanol, menthol, ethanol, an additive and water according to a proportion to obtain the menthol-based mosquito repellent liquid.
Example 3
A menthol-based mosquito repellent composition comprises 80kg of methanol, 6kg of menthol, 3kg of ethanol, 3kg of additives and 30kg of water.
Preferably, the menthol-based mosquito repellent composition of the present invention has a purity of 99.99% by volume of methanol.
Preferably, the preparation method of the menthol in the menthol-based mosquito repellent liquid composition comprises the following steps:
step 1: squeezing to obtain juice: selecting moldless mint, removing stems, and squeezing the mint to obtain mint juice;
and 2, step: low-temperature fermentation: inoculating yeast into the mint grass juice obtained in the step 1 according to the specification of 250mg/L, fermenting at a controlled temperature of 20 ℃, and cooling to 5 ℃ after fermentation for low-temperature storage;
and step 3: and (3) distilling the mint grass juice fermented in the step (2) in a distillation device at the distillation temperature of 90-95 ℃, and collecting distillate to obtain the menthol.
Preferably, the additives in the menthol-based mosquito repellent composition of the present invention include an emulsifier, a stabilizer, a cosolvent, a combustion improver and a dispersant.
Preferably, the menthol-based mosquito repellent composition of the present invention comprises soy lecithin as an emulsifier.
Preferably, the stabilizing agent in the menthol-based mosquito repellent composition of the present invention comprises di-tert-butyl-p-cresol and isobutylamine in a weight ratio of 3: 5.
Preferably, the cosolvent in the menthol-based mosquito repellent liquid composition is urea.
Preferably, the combustion improver in the menthol-based mosquito repellent composition of the present invention comprises hexyl ether, methyl tert-butyl ether and ethyl tert-butyl ether in a weight ratio of 2:3: 5.
Preferably, the dispersing agent in the menthol-based mosquito repellent composition of the present invention is N, N-dimethylformyl.
According to the formula, the preparation method of the menthol-based mosquito repellent composition comprises the following steps: and uniformly mixing methanol, menthol, ethanol, an additive and water according to a proportion to obtain the menthol-based mosquito repellent liquid.
The fragrance degree and the mosquito repelling duration of the obtained menthol-based mosquito repelling liquid were examined by examples 1 to 3, and the results of the examination were recorded as shown in Table 1
TABLE 1
| Degree of aromaticity | Duration of mosquito repelling/h | |
| Example 1 | Fragrance composition | 8 |
| Example 2 | Fragrance box | 7.5 |
| Example 3 | Fragrance composition | 6.5 |
The above description is only an example of the present invention, and is not intended to limit the present invention. Various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the scope of the claims of the present invention.
Claims (10)
1. The mosquito repellent liquid composition based on menthol is characterized by comprising, by weight, 60-80 parts of methanol, 4-6 parts of menthol, 2-3 parts of ethanol, 2-3 parts of an additive and 10-30 parts of water.
2. The menthol-based mosquito repellent liquid composition as claimed in claim 1, wherein the methanol has a purity of 99.99% by volume.
3. The menthol-based mosquito repellent liquid composition according to claim 1, wherein the preparation method of the menthol is as follows:
step 1: squeezing to obtain juice: selecting moldless mint, removing stems, and squeezing the mint to obtain mint juice;
and 2, step: and (3) low-temperature fermentation: inoculating yeast into the mint grass juice obtained in the step 1 according to the specification of 150-250mg/L, performing temperature-controlled fermentation at the temperature of 18-20 ℃, and cooling to 2-5 ℃ after fermentation for low-temperature storage;
and step 3: and (3) distilling the mint grass juice fermented in the step (2) in a distillation device at the distillation temperature of 90-95 ℃, and collecting distillate to obtain the menthol.
4. The menthol-based mosquito repellent liquid composition as claimed in claim 1, wherein the additive comprises an emulsifier, a stabilizer, a cosolvent, a combustion improver and a dispersant.
5. The menthol-based mosquito repellent composition according to claim 4, wherein the emulsifier is at least one of sorbitan monooleate, soybean lecithin and sucrose fatty acid ester.
6. A menthol-based mosquito repellent liquid composition according to claim 4, wherein the stabilizer comprises di-tert-butyl-p-cresol and isobutylamine in a weight ratio of 3: 5.
7. The menthol-based mosquito repellent liquid composition according to claim 4, wherein the cosolvent is at least one of oleic acid, p-aminobenzoic acid and urea.
8. A menthol-based mosquito repellent composition according to claim 4, wherein the combustion improver comprises hexyl ether, methyl tert-butyl ether and ethyl tert-butyl ether in a weight ratio of 2:3: 5.
9. A menthol-based mosquito repellent composition according to claim 4, wherein the dispersant is at least one of azomethylpyrrolidone, N-dimethylacetamide and N, N-dimethylformyl.
10. A preparation method of a menthol-based mosquito repellent liquid is characterized in that methanol, menthol, ethanol, an additive and water are uniformly mixed according to a proportion to obtain the menthol-based mosquito repellent liquid.
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