CN108991032B - Fly repellent and preparation method and application thereof - Google Patents
Fly repellent and preparation method and application thereof Download PDFInfo
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- CN108991032B CN108991032B CN201811259092.XA CN201811259092A CN108991032B CN 108991032 B CN108991032 B CN 108991032B CN 201811259092 A CN201811259092 A CN 201811259092A CN 108991032 B CN108991032 B CN 108991032B
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- essential oil
- fly
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- repellent
- litsea cubeba
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- 239000005871 repellent Substances 0.000 title claims abstract description 72
- 230000002940 repellent Effects 0.000 title claims abstract description 69
- 238000002360 preparation method Methods 0.000 title abstract description 22
- 239000000341 volatile oil Substances 0.000 claims abstract description 88
- 235000012854 Litsea cubeba Nutrition 0.000 claims abstract description 30
- 240000002262 Litsea cubeba Species 0.000 claims abstract description 28
- 239000000203 mixture Substances 0.000 claims abstract description 26
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- 241000333181 Osmanthus Species 0.000 claims abstract description 10
- 239000013543 active substance Substances 0.000 claims abstract description 7
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- 241001478387 Eupatorium lindleyanum Species 0.000 claims abstract description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- 241000255925 Diptera Species 0.000 claims description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 10
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 5
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- 239000002904 solvent Substances 0.000 claims description 4
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- 150000001413 amino acids Chemical class 0.000 claims description 2
- 239000004330 calcium propionate Substances 0.000 claims description 2
- 235000010331 calcium propionate Nutrition 0.000 claims description 2
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- OPGYRRGJRBEUFK-UHFFFAOYSA-L disodium;diacetate Chemical compound [Na+].[Na+].CC([O-])=O.CC([O-])=O OPGYRRGJRBEUFK-UHFFFAOYSA-L 0.000 claims description 2
- 239000000839 emulsion Substances 0.000 claims description 2
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- 239000001632 sodium acetate Substances 0.000 claims description 2
- 235000017454 sodium diacetate Nutrition 0.000 claims description 2
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- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 2
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- VEMKTZHHVJILDY-UXHICEINSA-N bioresmethrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OCC1=COC(CC=2C=CC=CC=2)=C1 VEMKTZHHVJILDY-UXHICEINSA-N 0.000 description 1
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- 229940079593 drug Drugs 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000003958 fumigation Methods 0.000 description 1
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- 231100000869 headache Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 208000029080 human African trypanosomiasis Diseases 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/24—Lauraceae [Laurel family], e.g. laurel, avocado, sassafras, cinnamon or camphor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Agronomy & Crop Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a fly repellent, a preparation method and application thereof, and the main active substances are as follows: the composition contains the essential oil of the litsea cubeba in Hunan, the essential oil of the eupatorium lindleyanum and the essential oil of the cinnamomum zeylanicum, and the composition comprises the following components in parts by weight: 40-65 parts of the essential oil of the seed of litsea cubeba in Hunan, 20-35 parts of the essential oil of the seed of euonymus alatus and 15-30 parts of the essential oil of the flower of lesser osmanthus. The invention adopts various plant-derived, safe and nontoxic essential oils as the main active ingredients of the fly repellent, so that the prepared fly repellent has the advantages of safety, no toxicity and difficulty in drug dependence. The single essential oil has an insignificant repellent effect, and the prepared fly repellent has a significant repellent effect on flies by utilizing the mutual synergistic effect of the litsea henryi essential oil, the eupatene essential oil and the artocarpus hypargyreus essential oil. The preparation process is simple, and the main raw materials are derived from plants, so that the environment is not polluted.
Description
Technical Field
The invention belongs to the technical field of plant-derived pesticides, and particularly relates to a fly repellent and a preparation method and application thereof.
Background
Flies are common insects in our lives, and because numerous bristles and hairs grow on the body surface, the flies can mechanically carry and transmit various pathogens, and are harmful to our lives. Besides disturbing people and polluting food, the fly harm is to spread various diseases and cause myiasis. The fly-borne diseases comprise two modes of mechanical transmission and biological transmission, wherein the mechanical transmission mainly transmits and spreads pathogens through actions of landing, licking, vomiting, excretion and the like, and the transmission mainly comprises digestive tract diseases (such as dysentery, cholera and the like), respiratory tract diseases (such as tuberculosis, pneumonia) and skin diseases; the biologically transmitted diseases mainly include that the tsetse fly (collecting fly) can transmit human trypanosomiasis (sleeping sickness). And fly larvae of flies can parasitize tissues and organs of human bodies and animals to cause myiasis. Musca domestica L belongs to the family of Diptera, is the most common fly in our lives, is a worldwide environment sanitary pest, is widely distributed in various parts of China, is a main activity place of kitchens, restaurants, food processing factories and the like, carries a large number of pathogenic bacteria, such as escherichia coli, oral ciliate bacteria, mycobacterium tuberculosis and the like, spreads a plurality of diseases such as typhoid fever, dysentery, cholera and the like, seriously threatens the health of human beings and disturbs the life of the human beings.
There are many methods of controlling flies, and fly repellents and insecticides are the most effective methods of use. At present, the fly insecticides such as pyrethroids are mainly chemically synthesized insecticides, but the insecticide resistance of the fly insecticides to the insecticides is in a remarkable rising trend, and the pyrethroid insecticides have certain acute toxicity and can cause symptoms such as dyspnea, cough, bronchospasm, nausea, vomiting, headache and the like. In order to solve the harm of chemosynthetic insecticides, researchers develop plant-derived fly repellents and insecticides, compared with chemosynthetic insecticides, repellents and insecticides prepared from plant extracts have certain repellent effect on flies, and have the characteristics of safety, low toxicity or no toxicity and difficulty in causing houseflies to generate drug resistance.
Disclosure of Invention
The invention aims to provide a safe and nontoxic fly repellent with a remarkable repellent effect, and a preparation method and application thereof.
The main active substances of the fly repellent are as follows: the composition contains the essential oil of the litsea cubeba in Hunan, the essential oil of the eupatorium lindleyanum and the essential oil of the cinnamomum zeylanicum, and the composition comprises the following components in parts by weight: 40-65 parts of the essential oil of the seed of litsea cubeba in Hunan, 20-35 parts of the essential oil of the seed of euonymus alatus and 15-30 parts of the essential oil of the flower of lesser osmanthus.
Preferably, the composition comprises the following components in parts by mass: 50-60 parts of the essential oil of the seed of litsea cubeba in Hunan, 25-30 parts of the essential oil of the seed of euonymus alatus and 20-25 parts of the essential oil of the flower of lesser osmanthus.
The essential oil of the litsea cubeba, the essential oil of the eupatorium japonicum and the essential oil of the cinnamomum pauciflorum are respectively extracted from the litsea cubeba fruit, the whole plant of the eupatorium japonicum and the cinnamomum pauciflorum leaf by a steam distillation method.
The composition is prepared by dissolving and mixing all components through a solvent, wherein the solvent accounts for 5-10% of the total mass of the composition.
The fly repellent comprises the following components in percentage by mass: 60-80% of the composition, 1-5% of an emulsifier, 0.1-0.5% of an antioxidant, 0.1-1% of a preservative, 1-8% of a humectant, 0.1-0.5% of a pH regulator and the balance of distilled water, wherein the total amount is 100%.
The fly repellent is emulsion.
The emulsifier is one or more of sorbitan fatty acid ester, propylene glycol fatty acid ester, sulfonate, carboxylate, sulfate and polyoxypropylene ether; the antioxidant is one or two of 2, 4-dimethyl-6-tert-butylphenol and 2, 5-di-tert-butylhydroquinone; the preservative is one or more of calcium propionate, sorbic acid and sodium diacetate; the humectant is one or more of hyaluronic acid, amino acid and polyalcohol; the pH regulator is citric acid or triethanolamine.
A preparation method of a fly repellent comprises the following steps: the fly repellent is obtained by uniformly mixing, emulsifying and homogenizing the components according to a set proportion.
The application of the fly repellent in repelling flies.
The repellent is applied to repelling houseflies in various places.
The fruit of litsea pungens can be used as medicine, so that the litsea pungens essential oil prepared by steam distillation is safe and non-toxic. The whole plant of the eupatorium contains a plurality of aromatic oils, and branches and leaves of the eupatorium can be used as Chinese herbal medicines, so the eupatorium essential oil prepared by steam distillation is safe and nontoxic. The cinnamon twig oil has high aromatic oil content, and the bark and the root of the cinnamon twig oil can also be used as medicines, so the cinnamon twig oil prepared by steam distillation is safe and nontoxic.
The invention has the beneficial effects that: the invention adopts various plant-derived, safe and nontoxic essential oils as the main active ingredients of the fly repellent, so that the prepared fly repellent has the advantages of safety, no toxicity and difficulty in drug dependence. The single essential oil has an insignificant repellent effect, and the prepared fly repellent has a significant repellent effect on flies by utilizing the mutual synergistic effect of the litsea henryi essential oil, the eupatene essential oil and the artocarpus hypargyreus essential oil. The preparation process is simple, and the main raw materials are derived from plants, so that the environment is not polluted.
Detailed Description
The main active substances of the fly repellent are as follows: the composition contains the litsea cubeba essential oil, the eupatene essential oil and the cinnamomum zeylanicum essential oil (the following 'plant fly-expelling agent composition') and comprises the following components in parts by mass: 40-65 parts of the essential oil of the seed of litsea cubeba in Hunan, 20-35 parts of the essential oil of the seed of euonymus alatus and 15-30 parts of the essential oil of the flower of lesser osmanthus. The preparation method comprises the steps of respectively dissolving the essential oil of the litsea cubeba in the Hunan, the essential oil of the eupatorium and the essential oil of the cinnamomum pauciflorum by using absolute ethyl alcohol, and then mixing, wherein the absolute ethyl alcohol accounts for 5-10% of the total weight of the composition.
The essential oil of the litsea cubeba is prepared from litsea cubeba (litsea cubeba)Litsea hunanensis) The fruit is obtained by steam distillation. The eupatorium essential oil is prepared from eupatorium (Elsholtzia rugulosa) The whole herb is obtained by steam distillation. The oligomate essential oil is prepared from oligomate (A)Cinnamomum pauciflorum) The leaves are obtained by steam distillation. The steam distillation method adopts conventional co-distillation.
In one embodiment, the fly repellant comprises the following components (the following mass percentages are based on the fly repellant as a whole): 60-80% of the composition, 1-5% of an emulsifier, 0.1-0.5% of an antioxidant, 0.1-1% of a preservative, 1-8% of a humectant and 0.1-0.5% of a pH regulator, wherein the fly repellent is prepared by uniformly mixing the raw materials in proportion, adding distilled water to 100%, emulsifying and homogenizing for 5-8 min. Then sampling to detect the stability and appearance of the preparation, and bottling after the preparation is qualified to obtain the finished product.
The following examples further illustrate the invention without limiting its scope.
Example 1
1) Preparation of active composition
Distilling the litsea cubeba fruits in Hunan with co-water to obtain litsea cubeba essential oil; distilling the whole weed of the eupatorium japonicum with water to obtain eupatorium japonicum essential oil; co-distilling the lesser osmanthus leaves to obtain the lesser osmanthus essential oil.
Mixing the litsea pungens essential oil, the wild fructus alpiniae oxyphyllae essential oil, the cortex cinnamomi japonici essential oil and the absolute ethyl alcohol according to the mass ratio of 50:25:20:5, and uniformly mixing to obtain the active composition.
2) Preparation of fly repellent
Uniformly mixing 75% of an active composition, 4% of an emulsifier (propylene glycol fatty acid ester), 0.3% of an antioxidant (2, 4-dimethyl-6-tert-butylphenol), 0.4% of a preservative (sorbic acid), 4% of a humectant (hyaluronic acid) and 0.3% of a pH regulator (citric acid) according to mass percentage, pumping the mixture into an emulsifying pot for emulsification, and homogenizing for 5min after emulsification is finished to obtain the fly repellent; and finally, sampling to detect the stability and appearance of the preparation, and bottling after the preparation is qualified to obtain the finished product of the fly repellent.
3) Test of repellent Effect of fly repellent
The repelling effect of the fly repellent is tested by adopting a Y-shaped olfactometer method under the condition of 3.0 mu L of dosage, and the repelling rate of the fly repellent to the houseflies within 20min is tested to be (92.5 +/-6.2)%. According to the standard of GB18418-2009 domestic sanitary insecticidal product electric heating liquid mosquito incense, the housefly is fumigated by a square box method, and half knock-down time KT of the fly repellent on the housefly is measured50The value is (13.7 +/-3.0) min, and the shorter the half knockdown time is, the stronger the fumigation knockdown effect of the repellent on the houseflies is.
Example 2
1) Preparation of active composition
Distilling the litsea cubeba fruits in Hunan with co-water to obtain litsea cubeba essential oil; distilling the whole weed of the eupatorium japonicum with water to obtain eupatorium japonicum essential oil; co-distilling the lesser osmanthus leaves to obtain the lesser osmanthus essential oil.
Mixing the litsea pungens essential oil, the wild fructus alpiniae oxyphyllae essential oil, the cortex cinnamomi japonici essential oil and the absolute ethyl alcohol according to the mass ratio of 40:30:25:5, and uniformly mixing to obtain the active composition.
2) Preparation of fly repellent
Uniformly mixing 60% of active composition, 4% of emulsifier (propylene glycol fatty acid ester), 0.3% of antioxidant (2, 4-dimethyl-6-tert-butylphenol), 0.4% of preservative (sorbic acid), 4% of humectant (hyaluronic acid) and 0.3% of pH regulator (citric acid) according to mass percentage, pumping into an emulsifying pot for emulsifying, and homogenizing for 5min after the emulsification is finished to obtain the fly repellent; and finally, sampling to detect the stability and appearance of the preparation, and bottling after the preparation is qualified to obtain the finished product of the fly repellent.
3) Test of repellent Effect of fly repellent
According to the test method of example 1, the repellent effect was tested as follows: the fly repellent prepared by the method has a fly repelling rate of (83.5 +/-3.4)%, within 20 min; half knock down time KT50The value was (17.2. + -. 2.1) min.
Comparative example 1
1) Active substance: mixing the litsea pungens essential oil with absolute ethyl alcohol according to the mass percentage of 95:5 to obtain the active substance.
2) Preparing a comparative fly repellent: uniformly mixing 60% of active substance, 4% of emulsifier (propylene glycol fatty acid ester), 0.3% of antioxidant (2, 4-dimethyl-6-tert-butylphenol), 0.4% of preservative (sorbic acid), 4% of humectant (hyaluronic acid) and 0.3% of pH regulator (citric acid) according to mass percentage, pumping into an emulsifying pot for emulsifying, and homogenizing for 5min after emulsifying to obtain the litsea cubeba essential oil fly repellent; and finally, sampling to detect the stability and appearance of the preparation, and bottling after the preparation is qualified to obtain the litsea pungens essential oil fly repellent finished product.
Comparative example 2
Changing the litsea cubeba essential oil in the comparative example 1 into the eupatorium adenophorum essential oil, and obtaining the eupatorium adenophorum essential oil fly repellent with the other conditions unchanged.
Comparative example 3
And (3) replacing the litsea pungens essential oil in the comparative example 1 with the cinnamomum subavenium essential oil, and obtaining the cinnamomum subavenium essential oil fly repellent under the same other conditions.
The repellent effects of the litsea pungens essential oil fly repellent, the euonymus japonicus essential oil fly repellent and the artocarpus hypargyreus essential oil fly repellent prepared in the comparative examples 1, 2 and 3 were respectively tested, and the test results were as follows:
the measured repellent rates of the litsea cubeba essential oil fly repellent, the euonymus japonicus essential oil fly repellent and the artocarpus hypargyreus hance essential oil fly repellent on the houseflies within 20min are respectively (56.5 +/-3.7)%, (45.5 +/-3.8)%, and (28.5 +/-2.4)%. Litsea pungens essential oil fly-repellent agent, eupatene essential oil fly-repellent agent and cinnamomum zeylanicum essential oil fly-repellent agent for half-knockdown time KT of housefly50The values are (24.2 + -3.0) min, (27.2 + -3.4) min and (30.5 + -4.0) min, respectively.
Compared with the example 2, the fly repellent prepared by the single essential oil in the comparative example has obviously weakened repellent and knockdown effects, which shows that after the litsea cubeba, the wild fructus alpiniae oxyphyllae and the cinnamomum wilsonii essential oil are mixed, the synergistic interaction effect is generated, so that the repellent effect is obviously improved.
To summarize the invention:
repeated tests of the inventor show that the composition obtained by compounding the litsea cubeba essential oil, the lindera fragrans essential oil and the artocarpus hypargyreus essential oil according to a certain proportion has obvious functions of repelling and knocking down the houseflies. After the three kinds of plant essential oil are mixed, the synergistic effect is obvious. The plant housefly repellent is safe to people and livestock, and has simple preparation method and simple and convenient implementation.
Claims (10)
1. A fly repellent is characterized in that the main active substances are as follows: the composition contains the essential oil of the litsea cubeba in Hunan, the essential oil of the eupatorium lindleyanum and the essential oil of the cinnamomum zeylanicum, and the composition comprises the following components in parts by weight: 40-65 parts of the essential oil of the seed of litsea cubeba in Hunan, 20-35 parts of the essential oil of the seed of euonymus alatus and 15-30 parts of the essential oil of the flower of lesser osmanthus.
2. The fly repellent according to claim 1, wherein the composition comprises the following components in parts by weight: 50-60 parts of the essential oil of the seed of litsea cubeba in Hunan, 25-30 parts of the essential oil of the seed of euonymus alatus and 20-25 parts of the essential oil of the flower of lesser osmanthus.
3. The fly repellent according to claim 1 or 2, wherein the essential oil of Litsea cubeba, Eugenia javanica and Osmanthus fragrans champ is extracted from Litsea cubeba fruit, Eugenia javanica whole plant and Osmanthus fragrans leaves of Hunan by steam distillation.
4. The fly repellent according to claim 1, wherein the composition is prepared by dissolving and mixing the components by a solvent, and the solvent accounts for 5-10% of the total mass of the composition.
5. The fly repellent according to claim 1, which comprises the following components in percentage by mass: 60-80% of the composition, 1-5% of an emulsifier, 0.1-0.5% of an antioxidant, 0.1-1% of a preservative, 1-8% of a humectant, 0.1-0.5% of a pH regulator and the balance of distilled water, wherein the total amount is 100%.
6. The fly repellant of claim 5, wherein the fly repellant is an emulsion.
7. The fly repellent according to claim 5, wherein the emulsifier is one or more of sorbitan fatty acid ester, propylene glycol fatty acid ester, sulfonate, carboxylate, sulfate and polyoxypropylene ether; the antioxidant is one or two of 2, 4-dimethyl-6-tert-butylphenol and 2, 5-di-tert-butylhydroquinone; the preservative is one or more of calcium propionate, sorbic acid and sodium diacetate; the humectant is one or more of hyaluronic acid, amino acid and polyalcohol; the pH regulator is citric acid or triethanolamine.
8. The fly repellant of claim 1 or 5, wherein a method of preparing the fly repellant comprises the steps of: the fly repellent is obtained by uniformly mixing, emulsifying and homogenizing the components according to a set proportion.
9. Use of the fly repellant of claim 1 or 5 to repel flies.
10. The use of a fly repellant according to claim 9 to repel flies, wherein the flies are houseflies.
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