CN114931617A - Preparation method of traditional Chinese medicine compound granules for treating AIDS-related symptoms - Google Patents
Preparation method of traditional Chinese medicine compound granules for treating AIDS-related symptoms Download PDFInfo
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- 239000008187 granular material Substances 0.000 title claims abstract description 51
- 208000030507 AIDS Diseases 0.000 title claims abstract description 36
- 239000003814 drug Substances 0.000 title claims abstract description 34
- 208000024891 symptom Diseases 0.000 title claims abstract description 34
- 150000001875 compounds Chemical class 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 34
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 34
- 235000008434 ginseng Nutrition 0.000 claims abstract description 34
- 244000274050 Platycodon grandiflorum Species 0.000 claims abstract description 19
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- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 17
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 17
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 17
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 17
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 17
- 235000010580 Psophocarpus tetragonolobus Nutrition 0.000 claims abstract description 17
- 241000046198 Triteleia hyacinthina Species 0.000 claims abstract description 17
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 17
- 235000011477 liquorice Nutrition 0.000 claims abstract description 17
- 235000001188 Peltandra virginica Nutrition 0.000 claims abstract description 16
- 239000002994 raw material Substances 0.000 claims abstract description 14
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 20
- 239000000341 volatile oil Substances 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 238000002156 mixing Methods 0.000 claims description 18
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- 239000007864 aqueous solution Substances 0.000 claims description 11
- 239000004375 Dextrin Substances 0.000 claims description 10
- 229920001353 Dextrin Polymers 0.000 claims description 10
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 10
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 10
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 10
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 10
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 10
- 229930006000 Sucrose Natural products 0.000 claims description 10
- 235000019425 dextrin Nutrition 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 10
- 238000001914 filtration Methods 0.000 claims description 10
- 239000011259 mixed solution Substances 0.000 claims description 10
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- 238000004519 manufacturing process Methods 0.000 abstract description 6
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- 239000002674 ointment Substances 0.000 abstract description 2
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- 238000000034 method Methods 0.000 description 1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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Abstract
The invention discloses a preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which relates to the technical field of traditional Chinese medicines and aims to solve the problems that the traditional Chinese medicine for treating AIDS-related symptoms is inconvenient to take, a large amount of medicines are required to be taken by a patient, the patient is caused to be in intense discomfort, active ingredients are not easy to be absorbed by a human body, and the using effect is poor, and the following scheme is proposed, wherein the traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following raw materials in parts by weight: 370 grams of ginseng, 360 grams of tuckahoe, 380 grams of stir-fried white hyacinth bean, 280 grams of platycodon grandiflorum, 220 grams of platycodon grandiflorum, 180 grams of lotus seed, 400 grams of liquorice, 410 grams of bran-fried atractylodes macrocephala, 420 grams of yam, 395 grams of yam, 190 grams of bran-fried coix seed and 200 grams of amomum fruit. The invention has reasonable design, improved ointment yield, easy extraction of effective components by human body, improved bioavailability, short production period, stable quality, convenient administration, small dosage, and good use effect.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms.
Background
AIDS is a very harmful infectious disease and is caused by infection of HIV, which is a virus capable of attacking the human immune system, and the most important CD4T lymphocyte in the human immune system is taken as a main attack target to destroy the cell in a large amount, so that the human body loses the immune function. Therefore, the human body is easy to be infected by various diseases and malignant tumors occur, and the fatality rate is high. In order to relieve the physical discomfort of AIDS patients, a preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms is urgently needed.
However, the existing traditional Chinese medicine for treating AIDS-related symptoms is inconvenient to take, causes strong discomfort of patients due to the need of taking a large amount of medicine, and has poor using effect because the effective components are not easy to be absorbed by human bodies.
Disclosure of Invention
The invention aims to solve the defects that the traditional Chinese medicine for treating the related symptoms of AIDS is inconvenient to take, a patient needs to take a large amount of medicines, the patient feels intense discomfort, the effective components are not easy to be absorbed by the human body, and the using effect is poor.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following raw materials in parts by weight:
390g of ginseng 370-.
In a preferred embodiment, the traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following raw materials in parts by weight:
405-410g of ginseng, 390-400g of tuckahoe, 300-310g of stir-fried white hyacinth bean, 190-200g of platycodon grandiflorum, 205-210g of lotus seed, 395-400g of liquorice, 395-400g of bran-fried atractylodes macrocephala, 380-390g of yam, 205-210g of bran-fried coix seed and 190-205g of amomum fruit.
In a preferred embodiment, the traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following raw materials in parts by weight:
400g of ginseng, 400g of tuckahoe, 300g of stir-fried white hyacinth bean, 200g of platycodon root, 200g of lotus seed, 400g of liquorice, 400g of stir-fried white atractylodes rhizome, 400g of Chinese yam, 200g of stir-fried coix seed and 200g of villous amomum fruit.
In a preferred embodiment, a method for preparing a Chinese medicinal compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient ginseng, tuckahoe, fried white hyacinth bean, platycodon root, lotus seed, liquorice, bran-fried bighead atractylodes rhizome, Chinese yam, bran-fried semen coicis and fructus amomi for later use;
s2: taking the fructus amomi and the bran-fried bighead atractylodes rhizome in the S1, lifting the volatile oil, distilling, and collecting the aqueous solution in another container;
s3: decocting the fructus Amomi and rhizoma Atractylodis Macrocephalae residue in S2, and the radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis preparata in S1 in water for three times;
s4: merging the decoctions in the step S3, filtering the mixed decoctions, and merging the aqueous solution in the step S2 and the filtered mixed decoctions;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of the clear paste in the S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: and drying the granules in the S6, adding the volatile oil in the S2, and uniformly mixing to prepare 4000g of the Chinese medicinal composition.
In a preferred embodiment, the time for the first decoction in S3 is 1.5 hours, and the time for the second and third decoctions is 1 hour.
In a preferred embodiment, the mixed decoction in S4 is passed through a screen of 180-200 meshes.
In a preferred embodiment, the fluid extract in S5 has a relative density of 1.20-1.25 and a temperature of 55 ℃.
The invention has reasonable design, improved ointment yield, easy extraction of effective components by human body, improved bioavailability, short production period, stable quality, convenient administration, small dosage, and good use effect.
Detailed Description
The present invention will be further illustrated with reference to the following specific examples.
Example one
The invention provides a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which comprises the following raw materials in parts by weight:
370g of ginseng, 360g of tuckahoe, 280g of stir-fried white hyacinth bean, 210g of platycodon root, 180g of lotus seed, 390g of liquorice, 410g of stir-fried white atractylodes rhizome, 395g of yam, 190g of stir-fried coix seed and 180g of amomum fruit.
A preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient Ginseng radix, Poria, parched semen lablab album, radix Platycodi, semen Nelumbinis, Glycyrrhrizae radix, Atractylodis rhizoma parched with bran, rhizoma Dioscoreae, Coicis semen parched with bran and fructus Amomi;
s2: extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma in S1, distilling, and collecting water solution in another container;
s3: decocting fructus Amomi and rhizoma Atractylodis Macrocephalae residue with bran in S2, and radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis with bran in S1 in water for three times;
s4: merging the decoction in the step S3, filtering the mixed decoction, and merging the aqueous solution in the step S2 and the filtered mixed decoction;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of clear paste in S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and uniformly mixing to prepare 4000 g.
In the embodiment, the time for the first decoction in S3 is 1.5 hours, the time for the second decoction and the time for the third decoction are both 1 hour, the mixed decoction in S4 needs to pass through a 180-mesh screen, the relative density of the clear paste in S5 is 1.20, the temperature is 55 ℃, the production period is short, and the use effect is good.
Example two
The invention provides a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which comprises the following raw materials in parts by weight:
390g of ginseng, 380g of tuckahoe, 290g of stir-fried white hyacinth bean, 220g of platycodon root, 190g of lotus seed, 400g of liquorice, 420g of stir-fried white atractylodes rhizome, 405g of yam, 20g of stir-fried coix seed with stir-fried bran and 200g of fructus amomi.
A preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient Ginseng radix, Poria, parched semen lablab album, radix Platycodi, semen Nelumbinis, Glycyrrhrizae radix, Atractylodis rhizoma parched with bran, rhizoma Dioscoreae, Coicis semen parched with bran and fructus Amomi;
s2: extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma in S1, distilling, and collecting water solution in another container;
s3: decocting fructus Amomi and rhizoma Atractylodis Macrocephalae residue with bran in S2, and radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis with bran in S1 in water for three times;
s4: mixing decoctions in S3, filtering the mixed decoctions, and mixing the aqueous solution in S2 with the filtered mixed decoctions;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of clear paste in S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and uniformly mixing to prepare 4000 g.
In the embodiment, the time for the first decoction in S3 is 1.5 hours, the time for the second decoction and the time for the third decoction are both 1 hour, the mixed decoction in S4 needs to pass through a 180-mesh screen, the relative density of the clear paste in S5 is 1.25, the temperature is 55 ℃, the dosage is small, and the using effect is good.
EXAMPLE III
The invention provides a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which comprises the following raw materials in parts by weight:
380g of ginseng, 370g of tuckahoe, 285g of fried white hyacinth bean, 220g of platycodon root, 185g of lotus seed, 395g of liquorice, 415g of bran-fried bighead atractylodes rhizome, 400g of Chinese yam, 195g of bran-fried coix seed and 190g of fructus amomi.
A preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient ginseng, tuckahoe, fried white hyacinth bean, platycodon root, lotus seed, liquorice, bran-fried bighead atractylodes rhizome, Chinese yam, bran-fried semen coicis and fructus amomi for later use;
s2: extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma in S1, distilling, and collecting water solution in another container;
s3: decocting fructus Amomi and rhizoma Atractylodis Macrocephalae residue with bran in S2, and radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis with bran in S1 in water for three times;
s4: mixing decoctions in S3, filtering the mixed decoctions, and mixing the aqueous solution in S2 with the filtered mixed decoctions;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of clear paste in S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and mixing uniformly to prepare 4000g of the Chinese medicinal composition.
In the embodiment, the time for the first decoction in the S3 is 1.5 hours, the time for the second decoction and the time for the third decoction are both 1 hour, the mixed decoction in the S4 needs to pass through a 185-mesh screen, the relative density of the clear paste in the S5 is 1.22, the temperature is 55 ℃, the taking comfort of a patient is improved, the effective components are easily absorbed by a human body, and the use effect is good.
Example four
The invention provides a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which comprises the following raw materials in parts by weight:
400g of ginseng, 400g of tuckahoe, 300g of stir-fried white hyacinth bean, 200g of platycodon root, 200g of lotus seed, 400g of liquorice, 400g of stir-fried bighead atractylodes rhizome, 400g of Chinese yam, 200g of stir-fried coix seed and 200g of villous amomum fruit.
A preparation method of a Chinese medicinal compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient Ginseng radix, Poria, parched semen lablab album, radix Platycodi, semen Nelumbinis, Glycyrrhrizae radix, Atractylodis rhizoma parched with bran, rhizoma Dioscoreae, Coicis semen parched with bran and fructus Amomi;
s2: extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma in S1, distilling, and collecting water solution in another container;
s3: decocting fructus Amomi and rhizoma Atractylodis Macrocephalae residue with bran in S2, and radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis with bran in S1 in water for three times;
s4: merging the decoction in the step S3, filtering the mixed decoction, and merging the aqueous solution in the step S2 and the filtered mixed decoction;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of the clear paste in the S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and mixing uniformly to prepare 4000g of the Chinese medicinal composition.
In the embodiment, the time for the first decoction in the S3 is 1.5 hours, the time for the second decoction and the time for the third decoction are both 1 hour, the mixed decoction in the S4 needs to pass through a 190-mesh screen, the relative density of the clear paste in the S5 is 1.25, the temperature is 55 ℃, the production period is short, the dose is small, the taking comfort of a patient is improved, the effective components are easily absorbed by a human body, and the use effect is good.
EXAMPLE five
The invention provides a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which comprises the following raw materials in parts by weight:
405g of ginseng, 390g of tuckahoe, 300g of stir-fried white hyacinth bean, 190g of platycodon root, 205g of lotus seed, 395g of liquorice, 395g of bran-fried bighead atractylodes rhizome, 380g of yam, 205g of bran-fried coix seed and 190g of fructus amomi.
A preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient ginseng, tuckahoe, fried white hyacinth bean, platycodon root, lotus seed, liquorice, bran-fried bighead atractylodes rhizome, Chinese yam, bran-fried semen coicis and fructus amomi for later use;
s2: extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma in S1, distilling, and collecting water solution in another container;
s3: decocting fructus Amomi and rhizoma Atractylodis Macrocephalae residue parched with bran in S2, and radix Ginseng, Poria, parched semen lablab album, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae and semen Coicis parched with bran in S1 in water for three times;
s4: mixing decoctions in S3, filtering the mixed decoctions, and mixing the aqueous solution in S2 with the filtered mixed decoctions;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of the clear paste in the S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and uniformly mixing to prepare 4000 g.
In the embodiment, the time for the first decoction in the S3 is 1.5 hours, the time for the second decoction and the time for the third decoction are both 1 hour, the mixed decoction in the S4 needs to pass through a 190-mesh screen, the relative density of the clear paste in the S5 is 1.24, the temperature is 60 ℃, the production period is short, the taking comfort of a patient is improved, the effective components are easily absorbed by a human body, and the use effect is good.
EXAMPLE six
The invention provides a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which comprises the following raw materials in parts by weight:
410g of ginseng, 400g of tuckahoe, 310g of stir-fried white hyacinth bean, 200g of platycodon root, 210g of lotus seed, 400g of liquorice, 400g of stir-fried bighead atractylodes rhizome, 390g of Chinese yam, 210g of stir-fried coix seed with stir-fried bran and 205g of fructus amomi.
A preparation method of a Chinese medicinal compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient Ginseng radix, Poria, parched semen lablab album, radix Platycodi, semen Nelumbinis, Glycyrrhrizae radix, Atractylodis rhizoma parched with bran, rhizoma Dioscoreae, Coicis semen parched with bran and fructus Amomi;
s2: extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma in S1, distilling, and collecting water solution in another container;
s3: decocting fructus Amomi and rhizoma Atractylodis Macrocephalae residue with bran in S2, and radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis with bran in S1 in water for three times;
s4: merging the decoction in the step S3, filtering the mixed decoction, and merging the aqueous solution in the step S2 and the filtered mixed decoction;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of clear paste in S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and uniformly mixing to prepare 4000 g.
In the embodiment, the time for the first decoction in the S3 is 1.5 hours, the time for the second decoction and the time for the third decoction are both 1 hour, the mixed decoction in the S4 needs to pass through a 190-mesh screen, the relative density of the clear paste in the S5 is 1.20, the temperature is 55 ℃, the taking comfort of a patient is improved, the effective components are easily absorbed by a human body, and the use effect is good.
EXAMPLE seven
The invention provides a traditional Chinese medicine compound granule for treating AIDS-related symptoms, which comprises the following raw materials in parts by weight:
400g of ginseng, 395g of tuckahoe, 305g of stir-fried white hyacinth bean, 195g of platycodon root, 210g of lotus seed, 398g of liquorice, 397g of stir-fried white atractylodes rhizome, 385g of Chinese yam, 206g of stir-fried coix seed and 195g of villous amomum fruit.
A preparation method of a traditional Chinese medicine compound granule for treating AIDS-related symptoms comprises the following steps:
s1: sequentially weighing sufficient Ginseng radix, Poria, parched semen lablab album, radix Platycodi, semen Nelumbinis, Glycyrrhrizae radix, Atractylodis rhizoma parched with bran, rhizoma Dioscoreae, Coicis semen parched with bran and fructus Amomi;
s2: extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma in S1, distilling, and collecting water solution in another container;
s3: decocting fructus Amomi and rhizoma Atractylodis Macrocephalae residue with bran in S2, and radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis with bran in S1 in water for three times;
s4: merging the decoction in the step S3, filtering the mixed decoction, and merging the aqueous solution in the step S2 and the filtered mixed decoction;
s5: concentrating the mixed solution in the step S4 to obtain clear paste;
s6: taking 1 part of clear paste in S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and uniformly mixing to prepare 4000 g.
In the embodiment, the time for the first decoction in S3 is 1.5 hours, the time for the second decoction and the time for the third decoction are both 1 hour, the mixed decoction in S4 needs to pass through a 90-mesh screen, the relative density of the clear paste in S5 is 1.20, the temperature is 55 ℃, the production period is short, and the use effect is good.
The preparation method comprises the following steps of firstly weighing sufficient ginseng, poria cocos, fried white hyacinth bean, platycodon grandiflorum, lotus seed, liquorice, bran-fried bighead atractylodes rhizome, Chinese yam, bran-fried semen coicis and fructus amomi for later use; extracting volatile oil from fructus Amomi and bran-parched Atractylodis rhizoma, distilling, and collecting water solution; decocting fructus Amomi, rhizoma Atractylodis Macrocephalae residue, radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis preparata with water for three times; mixing the decoctions, filtering, and mixing the water solution and the filtered mixed decoction; concentrating the mixed solution to obtain clear paste; taking clear paste 1 part, sucrose 2 parts, dextrin 2.5 parts and a proper amount of ethanol to prepare granules; drying the granules, adding the volatile oil, and mixing to obtain 4000 g.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (7)
1. A traditional Chinese medicine compound granule for treating AIDS-related symptoms is characterized by comprising the following raw materials in parts by weight:
370 grams of ginseng, 360 grams of tuckahoe, 380 grams of stir-fried white hyacinth bean, 280 grams of platycodon grandiflorum, 220 grams of platycodon grandiflorum, 180 grams of lotus seed, 400 grams of liquorice, 410 grams of bran-fried atractylodes macrocephala, 420 grams of yam, 395 grams of yam, 190 grams of bran-fried coix seed and 200 grams of amomum fruit.
2. The compound traditional Chinese medicine granule for treating AIDS-related symptoms according to claim 1, which is characterized by comprising the following raw materials in parts by weight:
405-410g of ginseng, 390-400g of tuckahoe, 300-310g of stir-fried white hyacinth bean, 190-200g of platycodon grandiflorum, 205-210g of lotus seed, 395-400g of liquorice, 395-400g of bran-fried atractylodes macrocephala, 380-390g of yam, 205-210g of bran-fried coix seed and 190-205g of amomum fruit.
3. The compound traditional Chinese medicine granule for treating AIDS-related symptoms according to claim 2, which is characterized by comprising the following raw materials in parts by weight:
400g of ginseng, 400g of tuckahoe, 300g of stir-fried white hyacinth bean, 200g of platycodon root, 200g of lotus seed, 400g of liquorice, 400g of stir-fried bighead atractylodes rhizome, 400g of Chinese yam, 200g of stir-fried coix seed and 200g of villous amomum fruit.
4. The preparation method of the compound traditional Chinese medicine granule for treating AIDS-related symptoms according to claim 3, which is characterized by comprising the following steps:
s1: sequentially weighing sufficient Ginseng radix, Poria, parched semen lablab album, radix Platycodi, semen Nelumbinis, Glycyrrhrizae radix, Atractylodis rhizoma parched with bran, rhizoma Dioscoreae, Coicis semen parched with bran and fructus Amomi;
s2: taking the fructus amomi and the bran-fried bighead atractylodes rhizome in the S1, lifting the volatile oil, distilling, and collecting the aqueous solution in another container;
s3: decocting the fructus Amomi and rhizoma Atractylodis Macrocephalae residue in S2, and the radix Ginseng, Poria, semen lablab album preparata, radix Platycodonis, semen Nelumbinis, radix Glycyrrhizae, rhizoma Dioscoreae, and semen Coicis preparata in S1 in water for three times;
s4: merging the decoctions in the step S3, filtering the mixed decoctions, and merging the aqueous solution in the step S2 and the filtered mixed decoctions;
s5: concentrating the mixed solution in the S4 to obtain clear paste;
s6: taking 1 part of the clear paste in the S5, 2 parts of cane sugar, 2.5 parts of dextrin and a proper amount of ethanol to prepare granules;
s7: drying the granules in the S6, adding the volatile oil in the S2, and uniformly mixing to prepare 4000g of the Chinese medicinal composition.
5. The preparation method of the compound traditional Chinese medicine granule for treating AIDS-related symptoms according to claim 4, which is characterized in that: in the S3, the time of the first decoction is 1.5 hours, and the time of the second decoction and the third decoction is 1 hour.
6. The preparation method of the compound traditional Chinese medicine granule for treating AIDS-related symptoms according to claim 4, which is characterized in that: the mixed decoction in S4 needs to pass through a screen of 180-200 meshes.
7. The preparation method of the compound traditional Chinese medicine granule for treating AIDS-related symptoms according to claim 4, which is characterized in that: the relative density of the clear paste in the S5 is 1.20-1.25, and the temperature is 55 ℃.
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CN1788783A (en) * | 2005-10-20 | 2006-06-21 | 北京汉典中西药研究开发中心 | Granule containing ginseng ,Siberian cocklebur ,lagehead atractylodes and its preparation method |
CN105056092A (en) * | 2015-08-21 | 2015-11-18 | 北京汉典制药有限公司 | Preparation method of ginseng, poria cocos and white atractylodes rhizome granules and prepared ginseng, poria cocos and white atractylodes rhizome granules |
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CN1788783A (en) * | 2005-10-20 | 2006-06-21 | 北京汉典中西药研究开发中心 | Granule containing ginseng ,Siberian cocklebur ,lagehead atractylodes and its preparation method |
CN105056092A (en) * | 2015-08-21 | 2015-11-18 | 北京汉典制药有限公司 | Preparation method of ginseng, poria cocos and white atractylodes rhizome granules and prepared ginseng, poria cocos and white atractylodes rhizome granules |
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Application publication date: 20220823 |