CN114917275A - Traditional Chinese medicine formula for treating herpes zoster and preparation method thereof - Google Patents
Traditional Chinese medicine formula for treating herpes zoster and preparation method thereof Download PDFInfo
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- CN114917275A CN114917275A CN202210537626.0A CN202210537626A CN114917275A CN 114917275 A CN114917275 A CN 114917275A CN 202210537626 A CN202210537626 A CN 202210537626A CN 114917275 A CN114917275 A CN 114917275A
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- 208000007514 Herpes zoster Diseases 0.000 title claims abstract description 43
- 239000003814 drug Substances 0.000 title claims abstract description 37
- 238000002360 preparation method Methods 0.000 title claims description 11
- 244000178320 Vaccaria pyramidata Species 0.000 claims abstract description 21
- 235000010587 Vaccaria pyramidata Nutrition 0.000 claims abstract description 21
- 244000153955 Reynoutria sachalinensis Species 0.000 claims abstract description 16
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 claims abstract description 16
- 239000000843 powder Substances 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 229940079593 drug Drugs 0.000 claims abstract description 7
- 235000011803 sesame oil Nutrition 0.000 claims description 15
- 239000008159 sesame oil Substances 0.000 claims description 15
- 238000000227 grinding Methods 0.000 claims description 10
- 239000011159 matrix material Substances 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 9
- 229940099259 vaseline Drugs 0.000 claims description 8
- 235000019484 Rapeseed oil Nutrition 0.000 claims description 7
- 240000001341 Reynoutria japonica Species 0.000 claims description 6
- 235000018167 Reynoutria japonica Nutrition 0.000 claims description 6
- 239000003906 humectant Substances 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000000758 substrate Substances 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 5
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 238000000034 method Methods 0.000 claims 3
- 235000014593 oils and fats Nutrition 0.000 claims 1
- 208000002193 Pain Diseases 0.000 abstract description 17
- 230000000694 effects Effects 0.000 abstract description 17
- 239000002674 ointment Substances 0.000 description 17
- 208000015181 infectious disease Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 208000032544 Cicatrix Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 230000037387 scars Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 241000239290 Araneae Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241000219321 Caryophyllaceae Species 0.000 description 1
- 201000006082 Chickenpox Diseases 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 241000701085 Human alphaherpesvirus 3 Species 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 241000219050 Polygonaceae Species 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 244000287839 Vaccinium bracteatum Species 0.000 description 1
- 235000005480 Vaccinium bracteatum Nutrition 0.000 description 1
- 206010046980 Varicella Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 210000000578 peripheral nerve Anatomy 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract
The invention relates to a traditional Chinese medicine formula for treating herpes zoster, which consists of the following raw material medicines in parts by weight: 5-15 parts of giant knotweed and 13-18 parts of cowherb seed; the invention can effectively treat herpes zoster, patients can feel comfortable as long as the medicinal powder is mixed into paste to be applied to affected parts, most people can feel obvious pain relief in about thirty minutes, and the treatment effect is achieved in 15-30 days generally; the prescription has the advantages of quick pain relieving and quick effect, can especially effectively treat initial herpes zoster, and solves the problem that the existing medicine for treating herpes zoster has poor treatment effect on herpes zoster.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine formula for treating herpes zoster and a preparation method thereof.
Background
Herpes zoster is an acute inflammatory dermatosis caused by varicella zoster virus, is called as herpes zoster and herpes zoster in traditional Chinese medicine, and is commonly called as spider sore and herpes zoster. It is mainly characterized by clustering water bubbles, and clustering zonal distribution along peripheral nerves at one side, accompanied with obvious neuralgia. Chickenpox appeared on the skin in the early stages. For example, improper treatment may cause motor nerve paralysis, easy complication of bacterial infection, constitutional differences of patients with herpes zoster, and different clinical manifestations of different types of symptoms, but all have damp-heat fire-toxin phenomena, such as red tongue, yellow and greasy tongue coating, slippery and rapid pulse or wiry and rapid pulse, so damp-heat is an important disease-treating factor, damp-heat is accumulated in vivo, viscera dysfunction, external invasion of toxic pathogen, and meridian blockage is the basic cause of the disease.
Although the existing Chinese patent medicine for treating herpes zoster has a plurality of components, the whole treatment effect is not ideal, and after a patient is coated with the ointment, the whole pain relieving effect is not obvious, so that the patient is difficult to endure pain, and money and manpower are consumed.
In summary, the present application provides a Chinese medicinal composition for treating herpes zoster and a preparation method thereof to solve the above problems.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine formula for treating herpes zoster and a preparation method thereof, and aims to solve the problems that although the traditional Chinese patent medicine for treating herpes zoster is multiple in components, the whole treatment effect is not ideal, the whole pain relieving effect is not obvious after a patient is coated with ointment, the patient is difficult to endure pain, and money and manpower are consumed.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine formula for treating herpes zoster is composed of the following raw material medicines in parts by weight: 5-15 parts of giant knotweed and 13-18 parts of cowherb seed.
Preferably, the weight ratio of each raw material medicine is as follows: 8-15 parts of giant knotweed and 13-15 parts of cowherb seed.
More preferably, the weight ratio of each raw material medicine is as follows: 15 parts of giant knotweed and 15 parts of cowherb seed.
A preparation method of a traditional Chinese medicine formula for treating herpes zoster comprises the following steps:
s1: grinding giant knotweed and cowherb seed into powder of 40-800 meshes by using a traditional Chinese medicine grinding machine, and weighing according to a formula for later use;
s2: preparing matrix suitable for normal temperature sesame oil or decocted sesame oil or heated and melted vaseline or rapeseed oil and the like;
s3: pouring the polygonum cuspidatum and the cowherb seed which are ground and crushed in the step S1 into a container for holding a substrate;
s4: continuously stirring the medicinal powder and the matrix until the mixture is blended into a uniform and fine paste;
s5: the paste in step S4 is taken out and then naturally cooled.
More preferably, in step S2, the humectant is poured into the decocting pot while the sesame oil is poured into the decocting pot.
More preferably, the humectant is vaseline, sesame oil, rapeseed oil or polyethylene glycol.
Compared with the prior art, the invention has the beneficial effects that: the invention can effectively treat herpes zoster, patients can feel comfortable as long as the medicinal powder is mixed into paste to be applied to affected parts, most people can feel obvious pain relief in about thirty minutes, and the medicine has a curing effect in 15-30 days in general; the prescription has the advantages of quick pain relieving and quick effect, can especially effectively treat initial herpes zoster, and solves the problem that the existing medicine for treating herpes zoster has poor treatment effect on herpes zoster.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
The current research situation of the medicinal materials related to the traditional Chinese medicine is as follows:
giant knotweed rhizome: is prepared from dried rhizome and root of Polygonum cuspidatum of Polygonaceae by digging in spring and autumn, and removing fibrous root, and has effects of promoting diuresis, eliminating jaundice, clearing away heat and toxic materials, removing blood stasis, and relieving pain.
Cowherb seed: is dried mature seed of Vaccinium Bracteatum L of Caryophyllaceae, and is harvested in summer when fruit is mature and pericarp is not cracked, and has effects of promoting blood circulation, dredging channels, promoting lactation, relieving swelling, inducing diuresis, and treating stranguria.
Example one
The external ointment of the embodiment is prepared from the following raw material medicines in parts by weight: 5 parts of giant knotweed and 13 parts of cowherb seed.
The preparation method of the external ointment in the embodiment comprises the following steps:
s1: grinding giant knotweed and cowherb seed into powder of 40-800 meshes by using a traditional Chinese medicine grinding machine, and weighing according to a formula for later use;
s2: preparing matrix suitable for normal temperature sesame oil or decocted sesame oil or heated and melted vaseline or rapeseed oil and the like;
s3: pouring the polygonum cuspidatum and the cowherb seed which are ground and crushed in the step S1 into a container for holding a substrate;
s4: continuously stirring the medicinal powder and the matrix until the mixture is blended into a uniform and fine paste;
s5: the paste in step S4 is taken out and then naturally cooled.
Example two
The external ointment of the embodiment is prepared from the following raw material medicines in parts by weight: 7 parts of giant knotweed and 15 parts of cowherb seed.
The preparation method of the external ointment in the embodiment comprises the following steps:
s1: grinding giant knotweed and cowherb seed into powder of 40-800 meshes by using a traditional Chinese medicine grinding machine, and weighing according to a formula for later use;
s2: preparing matrix suitable for normal temperature sesame oil or decocted sesame oil or heated and melted vaseline or rapeseed oil;
s3: pouring the polygonum cuspidatum and the cowherb seed which are ground and crushed in the step S1 into a container for holding a substrate;
s4: continuously stirring the medicinal powder and the matrix until the mixture is blended into a uniform and fine paste;
s5: the paste in step S4 is taken out and then naturally cooled.
EXAMPLE III
The external ointment of the embodiment is prepared from the following raw material medicines in parts by weight: 15 parts of giant knotweed and 15 parts of cowherb seed.
The preparation method of the external ointment in the embodiment comprises the following steps:
s1: grinding the giant knotweed rhizome and the cowherb seed into powder of 40-800 meshes by using a traditional Chinese medicine grinding machine, and weighing according to a formula for later use;
s2: preparing matrix suitable for normal temperature sesame oil or decocted sesame oil or heated and melted vaseline or rapeseed oil and the like;
s3: pouring the polygonum cuspidatum and the cowherb seed which are ground and crushed in the step S1 into a container for holding a substrate;
s4: continuously stirring the medicinal powder and the matrix until the mixture is blended into a uniform and fine paste;
s5: the paste in step S4 is taken out and then naturally cooled.
The external ointment has the following actual clinical cases:
case 1: wangzhi, male, 42 years old, had infection in the back waist, had not been treated in hospital in time in the initial stage of infection, and had not been prohibited from eating too much, had been diagnosed as herpes zoster at present, and the blister became the rupture trend, the patient was restless;
the ointment in the first embodiment is applied once a day at night, pain is obviously relieved thirty minutes later, the effect is obvious after 7 days, and the herpes zoster disappears after 20 days without pain; after 6 months of treatment, no recurrence occurs, and the conclusion is that the disease is cured.
Case 2: tian Yi, a female, aged 53, had infection in the abdomen, itching with stinging, rupture of part of blisters with signs of infection, and was diagnosed as herpes zoster in hospitals;
the ointment in the second embodiment is applied once every night, and is applied again after severe pain, scars disappear after 1 month, residual pain disappears, skin recovers, and the ointment is reviewed in a hospital 3 times after 6 months of treatment without recurrence, and the conclusion is that the ointment is cured.
Case 3: zhao, female 56 years old, severe facial herpes zoster was diagnosed in hospitals, and had cluster rash accompanied by itching and scratching and winding phenomena during stabbing pain;
the ointment in the third embodiment is applied once every night, the herpes zoster is cured after 10 days without scars, and the herpes zoster is reexamined in a hospital within 12 months after treatment without sequelae, so that the herpes zoster is cured.
In conclusion, patients feel comfortable as long as the medicinal powder is mixed into paste to be applied to affected parts, most people feel obvious pain relief in about thirty minutes, and the medicinal powder has a healing effect in 15-30 days generally; the prescription has the advantages of quick pain relieving and quick effect, can especially effectively treat initial herpes zoster, and solves the problem that the existing medicine for treating herpes zoster has poor treatment effect on herpes zoster.
The cases are only the cases of treatment, the traditional Chinese medicine ointment for treating herpes zoster is applied to 35 cases of initial herpes zoster, 15 cases of mild herpes zoster and 20 cases of severe herpes zoster, the cure rate is more than eighty percent, most patients have the effect in half an hour after the ointment is coated, and after the ointment is applied for three treatment courses, the patients are basically cured, and the treatment effect is obvious.
Wherein the humectant is vaseline, oleum Sesami, oleum Rapae or polyethylene glycol, or other substances capable of realizing related functions;
wherein, on the basis of the prescription, other various external preparations can be prepared by utilizing the forms of extracts, extracts and the like of the raw material medicines.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. A traditional Chinese medicine formula for treating herpes zoster is characterized in that: the traditional Chinese medicine composition is composed of the following raw material medicines in parts by weight: 5-15 parts of giant knotweed and 13-18 parts of cowherb seed.
2. The traditional Chinese medicine formula for treating herpes zoster according to claim 1, which is characterized in that: the weight ratio of each raw material medicine is as follows: 8-15 parts of giant knotweed and 13-15 parts of cowherb seed.
3. The traditional Chinese medicine formula for treating herpes zoster according to claim 1, which is characterized in that: the weight ratio of each raw material medicine is as follows: 15 parts of giant knotweed and 15 parts of cowherb seed.
4. A preparation method of a traditional Chinese medicine formula for treating herpes zoster is characterized by comprising the following steps: the method comprises the following steps:
s1: grinding giant knotweed and cowherb seed into powder of 40-800 meshes by using a traditional Chinese medicine grinding machine, and weighing according to a formula for later use;
s2: preparing matrix suitable for normal temperature sesame oil or decocted sesame oil or heated and melted vaseline or rapeseed oil and the like;
s3: pouring the polygonum cuspidatum and the cowherb seed which are ground and crushed in the step S1 into a container for holding a substrate;
s4: continuously stirring the medicinal powder and the matrix until the mixture is blended into a uniform and fine paste;
s5: the paste in step S4 is taken out and then naturally cooled.
5. The method for preparing a Chinese medicinal composition for treating herpes zoster according to claim 4, which is characterized by comprising the following steps: in step S2, sesame oil and other oils and fats having similar properties to sesame oil are used as a base, and a humectant is poured into a container containing the base.
6. The method for preparing a Chinese medicinal composition for treating herpes zoster according to claim 5, which is characterized by comprising the following steps: the humectant is similar to vaseline, sesame oil, rapeseed oil or polyethylene glycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210537626.0A CN114917275A (en) | 2022-05-18 | 2022-05-18 | Traditional Chinese medicine formula for treating herpes zoster and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210537626.0A CN114917275A (en) | 2022-05-18 | 2022-05-18 | Traditional Chinese medicine formula for treating herpes zoster and preparation method thereof |
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| CN114917275A true CN114917275A (en) | 2022-08-19 |
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|---|---|---|---|
| CN202210537626.0A Pending CN114917275A (en) | 2022-05-18 | 2022-05-18 | Traditional Chinese medicine formula for treating herpes zoster and preparation method thereof |
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| Country | Link |
|---|---|
| CN (1) | CN114917275A (en) |
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2022
- 2022-05-18 CN CN202210537626.0A patent/CN114917275A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 陈文林等: "王不留行子外搽治疗带状疱疹56例" * |
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Application publication date: 20220819 |