CN114807042A - 一种嵌合抗原受体改造的nk细胞及其制备方法与应用 - Google Patents

一种嵌合抗原受体改造的nk细胞及其制备方法与应用 Download PDF

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CN114807042A
CN114807042A CN202210074663.2A CN202210074663A CN114807042A CN 114807042 A CN114807042 A CN 114807042A CN 202210074663 A CN202210074663 A CN 202210074663A CN 114807042 A CN114807042 A CN 114807042A
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acid sequence
dadl
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李晓东
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Nanjing Zhutianzhongke Technology Development Co ltd
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CN202210074663.2A 2021-01-22 2022-01-21 一种嵌合抗原受体改造的nk细胞及其制备方法与应用 Pending CN114807042A (zh)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107188969A (zh) * 2011-04-08 2017-09-22 美国卫生和人力服务部 抗‑表皮生长因子受体变体iii嵌合抗原受体及其用于治疗癌症的用途
CN107667170A (zh) * 2015-06-01 2018-02-06 Ucl商务股份有限公司 细胞
CN110114371A (zh) * 2016-11-11 2019-08-09 奥托路斯有限公司 嵌合抗原受体
CN110257338A (zh) * 2018-06-21 2019-09-20 上海斯丹赛生物技术有限公司 嵌合细胞因子受体

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* Cited by examiner, † Cited by third party
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AU2013221672B2 (en) * 2012-02-13 2017-11-09 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
CN107988164B (zh) * 2016-10-26 2020-07-07 阿思科力(苏州)生物科技有限公司 一种pd-1 car nk-92细胞及其制备方法与应用
CN107759701B (zh) * 2017-10-27 2021-07-02 杭州优善生物科技有限公司 嵌合抗原受体、其修饰的NK细胞、编码DNA、mRNA、表达载体、制备方法和应用
CN110079502B (zh) * 2018-02-07 2020-11-06 阿思科力(苏州)生物科技有限公司 Pd-l1 car-nk细胞及其制备和应用
CN109207430A (zh) * 2018-09-25 2019-01-15 华东师范大学 一种嵌合抗原受体nk细胞及其制备方法和应用
JP7092404B2 (ja) * 2018-10-31 2022-06-28 イミュニティーバイオ、インコーポレイテッド Pd-l1キメラ抗原受容体を発現するnk細胞によるpd-l1陽性悪性腫瘍の排除
CN112279922B (zh) * 2019-07-22 2023-07-28 南京助天中科科技发展有限公司 一种吞噬细胞嵌合抗原受体及其应用
CN110964697B (zh) * 2019-12-19 2023-07-18 中国海洋大学 一种抗肿瘤nk细胞及其制备方法和应用
CN112029729B (zh) * 2020-09-09 2023-03-31 广东昭泰体内生物医药科技有限公司 Cd19和cd22双靶点嵌合抗原受体nk细胞及其应用
CN112048481B (zh) * 2020-09-09 2023-02-10 广东昭泰体内生物医药科技有限公司 一种靶向cd19的嵌合抗原受体nk细胞及其应用

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107188969A (zh) * 2011-04-08 2017-09-22 美国卫生和人力服务部 抗‑表皮生长因子受体变体iii嵌合抗原受体及其用于治疗癌症的用途
CN107667170A (zh) * 2015-06-01 2018-02-06 Ucl商务股份有限公司 细胞
CN110114371A (zh) * 2016-11-11 2019-08-09 奥托路斯有限公司 嵌合抗原受体
CN110257338A (zh) * 2018-06-21 2019-09-20 上海斯丹赛生物技术有限公司 嵌合细胞因子受体

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