CN114796383A - Traditional Chinese medicine stomach-protecting powder for preventing stomach cancer - Google Patents

Traditional Chinese medicine stomach-protecting powder for preventing stomach cancer Download PDF

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CN114796383A
CN114796383A CN202210406908.7A CN202210406908A CN114796383A CN 114796383 A CN114796383 A CN 114796383A CN 202210406908 A CN202210406908 A CN 202210406908A CN 114796383 A CN114796383 A CN 114796383A
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stomach
traditional chinese
patients
protecting powder
chinese medicine
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史玉林
史迪文
史博文
史大程
张媛媛
史大鹏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention relates to a traditional Chinese medicine stomach-protecting powder for preventing stomach cancer. It can not only completely cure four refractory stomach diseases such as atrophic gastritis, erosive gastritis, helicobacter pylori and gastric ulcer which can be developed into gastric cancer, but also prevent gastric cancer; meanwhile, the traditional Chinese medicine composition has excellent prevention and treatment effects on patients with superficial gastritis, enteritis, reflux esophagitis, duodenal ulcer, gastric mucosa injury caused by frequent drinking, spicy and hot eating, overeating, frequent taking of antirheumatic drugs, antihypertensive drugs and anticancer drugs, and part of patients with halitosis. The stomach protecting powder belongs to nontoxic grade, and has no toxic or side effect on human, so the stomach protecting powder can be taken no matter how big or small people or the physique of patients, and the patients suffer from the gastropathy.

Description

Traditional Chinese medicine stomach-protecting powder for preventing stomach cancer
(I) technical field
The invention relates to a traditional Chinese medicine stomach-protecting powder for preventing stomach cancer, which can cure various stomach diseases and prevent the occurrence of stomach cancer
The specific Chinese patent medicine belongs to a new medicine and a new technology for treating gastropathy and preventing gastric cancer.
(II) background of the invention
According to the survey of the world health organization of the united nations, more than 50 percent of people all over the world suffer from stomach diseases, the cancer mortality rate of the world is 25 percent of stomach cancer, and half of new cases of the stomach cancer all over the world come from China, so that the research and development of the specific traditional Chinese medicine for preventing the stomach cancer is urgent.
The medical scientist recognizes: there are many gastric diseases, but only four gastric diseases, atrophic gastritis, erosive gastritis, helicobacter pylori and gastric ulcer, can develop into gastric cancer. In other words, the four stomach diseases are cured, and the gastric cancer is prevented.
Disclosure of the invention
The tests of pharmacology, drug effect, toxicology and the like and a large number of clinical application experiments prove that the stomach-protecting powder is prepared in four years: the secret recipe medicine can thoroughly cure the four stomach diseases which cause the gastric cancer. The roots of the four diseases, such as atrophic gastritis, erosive gastritis, helicobacter pylori, gastric ulcer and the like, are that gastric mucosa is damaged in different degrees, and if the gastric mucosa is repaired, the four gastric diseases can be thoroughly cured.
The research of marine pharmacology experts proves that: calcium carbonate contained in cuttlebone in the stomach protecting powder can neutralize gastric acid, so that stimulation and damage of gastric acid to gastric mucosa at a focus can be reduced, and meanwhile, the stimulation and damage to gastric mucosa at a pathological part can be further reduced due to the change of the pH value of gastric content and the reduction of the activity of pepsin, and the gastric protecting powder is further beneficial to the repair of the gastric mucosa at the focus.
In addition, after the colloid contained in the cuttlebone reacts with organic matters in the stomach and gastric acid, a protective film can be formed on the gastric mucosa and the ulcer surface thereof, and the repair of the damaged gastric mucosa is facilitated. Meanwhile, experiments prove that: the cuttlebone can not only promote the synthesis of PGE2 of rat gastric mucosa, but also increase the synthesis of PGE2 of stress and acetic gastric ulcer model rat gastric mucosa, and the functions are both favorable for the protection and the repair of the gastric mucosa.
A large number of animal experiments and clinical experiments of tested human groups in the disease control center of Hunan province of the national authoritative testing organization also prove that the stomach-protecting powder has the effects of protecting and repairing the gastric mucosa of animals and human bodies. Therefore, the stomach protecting powder can thoroughly cure the four stomach diseases, namely, the stomach protecting powder can cure the root of the disease.
The animal experiment experimental group uses 2.5g/kg of stomach protecting powder and 1 percent of carboxymethyl cellulose to perfuse the stomach of a rat for 30 days continuously; the control group rats were gavaged with 1% carboxymethylcellulose for 30 consecutive days. On the day of experiment completion, both groups of rats were gavaged with 1 ml/rat of absolute alcohol, and then sacrificed for anatomical observation of lesions of gastric mucosal lesions as shown in the following table.
Total area of gastric mucosa hyperemia and diffuse bleeding (x + -s)
Group of Animal number (only) Area (mm) 2 ) P
Control group 10 34.70±9.46 ……
Experimental group 10 21.70±7.18 0.009
The experiment proves that the stomach protecting powder has obvious protective effect on the damage of the gastric mucosa of animals
The human body test feeding experiment that the stomach protecting powder has the functions of protecting and repairing the damage of the gastric mucosa is to randomly divide voluntary subjects meeting the experiment standard into a test feeding group and a control group. The 'Jinhai stomach-protecting powder' and the placebo are respectively taken for 45 days according to the recommended dose, and after the experiment is finished, the result of the statistical treatment of each index data is as follows:
improvement of clinical symptoms
Figure BSA0000271400100000021
Gastroscopy gastric mucosa injury repair condition
Figure BSA0000271400100000022
The experiment proves that: the stomach protecting powder has obvious protection and repair functions on gastric mucosa of a human body.
The stomach-protecting powder is prepared from various traditional Chinese medicines, and has scientific formula, comprehensive action and multiple functions. In the formula, astragalus mongholicus, qi tonifying, yang rising, spleen tonifying, stomach invigorating, rhizoma cyperi, qi circulation promoting, spleen warming and stomach harmonizing, cuttlebone, chicken's gizzard-membrane, stomach invigorating, bleeding stopping, antacid and pain relieving, rhizoma corydalis, angelica dahurica, blood circulation promoting, pain relieving, qi regulating and middle warmer regulating, cassia twig, spleen warming, yang supporting, szechwan chinaberry fruit, qi circulation promoting, pain relieving, bulbus fritillariae cirrhosae, antacid and convulsion relieving, angelica sinensis, blood circulation promoting, bleeding stopping and pain relieving are matched with each other to realize synergistic interaction, so that the traditional Chinese medicine can treat both symptoms and root causes, and can stop medicine thoroughly after healing. Unlike some stomach medicines, it is not necessary to take the medicine for stomach pain and then take the medicine for stomach pain, which is the essential difference between stomach-protecting powder and other stomach medicines that are currently available.
Most of the stomach-protecting powder is a traditional Chinese medicine with homology of medicine and food, and a large number of animal experiments and clinical experiments in the disease control center of Hunan province verify that the Mingjin Haiwai stomach-protecting powder belongs to a nontoxic grade, so that the stomach-protecting powder can be taken by adults, children and patients regardless of constitutions, and is suitable for a large number of people.
The clinical application also finds that the stomach protecting powder can completely cure four stomach diseases of atrophic gastritis, erosive gastritis, helicobacter pylori and gastric ulcer which cause gastric cancer, and has excellent treatment and prevention effects on patients with gastric mucosa injury and part of halitosis caused by frequent drinking, eating spicy soup, overeating, frequent taking of anti-rheumatism drugs, anti-cancer drugs, antihypertensive drugs and the like.
(IV) detailed description
A large number of clinical applications prove that the total effective rate of the stomach protecting powder for treating the stomach diseases reaches over 96.2 percent.
The cure rate reaches more than 90 percent (40 patients in atrophic gastritis medical record group are continuously taken for 3-5 months, 38 patients are cured and 2 patients become non-atrophic gastritis after gastroscope review, 50 patients in erosive gastritis medical record group are cured and 48 patients are cured and 2 patients are obviously improved after gastroscope review for 2-3 months, 50 patients in gastric ulcer disease record group are cured and 2 patients are obviously improved and 1 patient is slightly improved after gastroscope review for 3 months, 40 patients in helicobacter pylori medical record group are continuously taken for 1-1.5 months, and 40 patients are all cured after c14 exhalation test),
for example, if a certain one of Shandong's king takes the stomach-protecting powder for one month, the four stomach diseases of atrophic gastritis, erosive gastritis, helicobacter pylori and gastric ulcer which are suffered by the powder can be completely cured.

Claims (2)

1. A traditional Chinese medicine stomach-protecting powder for preventing stomach cancer is characterized in that the stomach-protecting powder comprises the following components by weight: 150g of astragalus, 100g of rhizoma cyperi, 200g of endothelium corneum gigeriae galli, 200g of cuttlebone, 100g of angelica, 100g of bulbus fritillariae cirrhosae, 150g of rhizoma corydalis, 100g of szechwan chinaberry fruit, 100g of cassia twig and 150g of radix angelicae.
2. The traditional Chinese medicine stomach-protecting powder for preventing gastric cancer according to claim 1, characterized in that all the traditional Chinese medicines of all the formulas and the contents thereof in the stomach-protecting powder formula are mixed, crushed into fine powder, stirred evenly, filled into plastic packaging bags (5 g per bag) for packaging medicines, and sterilized; patients with gastropathy take the medicine 2 times daily, 1 bag with warm water each time.
CN202210406908.7A 2022-04-07 2022-04-07 Traditional Chinese medicine stomach-protecting powder for preventing stomach cancer Pending CN114796383A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111729033A (en) * 2020-04-21 2020-10-02 史玉林 Specific traditional Chinese medicine stomach-protecting powder for preventing stomach cancer
CN113769013A (en) * 2021-09-14 2021-12-10 史玉林 Traditional Chinese medicine stomach-protecting powder for preventing stomach cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111729033A (en) * 2020-04-21 2020-10-02 史玉林 Specific traditional Chinese medicine stomach-protecting powder for preventing stomach cancer
CN113769013A (en) * 2021-09-14 2021-12-10 史玉林 Traditional Chinese medicine stomach-protecting powder for preventing stomach cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王立新等: "扶正散结汤配合手术与化疗治疗消化系恶性肿瘤320例分析", 《中原医刊》 *

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