CN114796054B

CN114796054B - Hair loss prevention scalp care composition, and preparation method and application thereof

Info

Publication number: CN114796054B
Application number: CN202210524479.3A
Authority: CN
Inventors: 阮景波; 李传茂; 张伟杰; 张楚标; 曾伟丹
Original assignee: Guangdong Danz Group Co Ltd; Guangzhou Keneng Cosmetic Research Co Ltd
Current assignee: Guangdong Danz Group Co Ltd; Guangzhou Keneng Cosmetic Research Co Ltd
Priority date: 2022-05-13
Filing date: 2022-05-13
Publication date: 2023-10-20
Anticipated expiration: 2042-05-13
Also published as: CN114796054A

Abstract

The invention provides an anti-hair loss scalp care composition, which comprises a bright cola seed extract and an inonotus obliquus extract; the content of the extract of the bright cola seeds is 0.01-99.99% based on 100% of the total mass of the hair loss prevention scalp care composition; the content of Inonotus obliquus extract is 0.01-99.99%. The raw materials of the hair loss prevention scalp care composition of the invention are easy to obtain, and the hair loss prevention effect is excellent.

Description

Hair loss prevention scalp care composition, and preparation method and application thereof

Technical Field

The invention relates to an anti-hair loss scalp care composition, and a preparation method and application thereof, and belongs to the field of daily chemicals.

Background

Alopecia is a phenomenon of hair loss, and is divided into physiological and pathological aspects. Physiological alopecia refers to the normal shedding of hair. Pathologic alopecia refers to abnormal or excessive hair loss. With the increasing social pressure and the increasing pace of life, the environment is worsened and the eating habit of bad diet is increased, and the number of patients suffering from alopecia is increased along with the increasing unhealthy and sub-healthy conditions. Alopecia has a great influence on appearance and self-confidence, and even on marital, occupation and progress.

In general, pathological hair loss can be divided into two basic types, permanent hair loss due to damaged hair follicles, and temporary hair loss due to short-term damage to hair follicles. The hair loss process of permanent alopecia (i.e., male pattern alopecia) is gradually generated, and the hair edges of the forehead part are obviously retracted at the beginning, and the hair at the top of the head is thin; then gradually develop, and finally only the back of the head is left, and the hair is sparse on both sides of the head. Temporary alopecia is often caused by diseases that result in high fever. However, ingestion of metals (such as thallium, tin and arsenic) or drugs, malnutrition, certain inflammatory dermatological disorders, chronic wasting diseases, and endocrine dyscrasias can also cause temporary alopecia upon X-ray.

In the prior art, three main methods are currently available on the market to reduce hair loss and improve hair: 1. botulinum toxin was used: the botulinum toxin blocks the transmission of nerve signals, so that scalp tissues are in a loose state, and hair can be conveniently grown; however, after long-term and repeated use, scalp tissue becomes thin and hair follicle soil is damaged; 2. hyaluronic acid was used: hair growth can be promoted by supplementing water and corresponding nutrition, but multiple uses can cause imbalance (hypotonic) of scalp tissue osmotic pressure; 3. hair transplantation: the operation process is complicated, the pain is obvious, the cost is relatively high, and the problem of survival rate after hair follicle transplantation can not be solved.

Citation 1 provides a hair tonic composition which contains a lipase derived from bacteria, i.e., a lipid degrading enzyme which appears to have antibacterial activity. Disadvantages of such compositions are the resulting dryness of the hair, itching and irritation of the scalp, unpleasant odors after application to the hair skin and possible damage to the hair skin/scalp over prolonged use.

Citation 2 discloses an anti-hair loss repair composition and its application. The hair loss prevention and repair composition consists of the following components: hair follicle progenitor cells, mesenchymal stem cell factors, mesenchymal stem cell lysate and platelet-rich fibrin; wherein, every 10mL of mesenchymal stem cell lysate and (1-10) x 10 ⁶ The number of progenitor cells of the hair follicle,0.2-0.6mL mesenchymal stem cell factor, 0.2-0.6mL platelet rich fibrin; the mesenchymal stem cell lysate is prepared by a method comprising the following steps: (1-10). Times.10 ⁷ After digestion of the mesenchymal stem cells, they were dissolved in 10mL of physiological saline. However, the hair follicle progenitor cells, mesenchymal stem cell factors, mesenchymal stem cell lysate, platelet-rich fibrin and the like required by the method are difficult to obtain, so that the cost is excessive.

Citation 1: US4737362a

Citation 2: CN111840330A

Disclosure of Invention

Problems to be solved by the invention

In view of the technical problems in the prior art, the invention provides an anti-hair loss scalp care composition. The raw materials of the hair loss prevention scalp care composition are easy to obtain, and the hair loss prevention effect is excellent.

Furthermore, the invention also provides a scalp care essence which can directly act on scalp and has excellent alopecia preventing effect.

Furthermore, the invention also provides a preparation method of the hair loss prevention scalp care composition and the care essence, the preparation method is simple and easy to implement, raw materials are easy to obtain, and the hair loss prevention scalp care composition and the care essence are suitable for mass production.

Solution for solving the problem

The invention provides an anti-hair loss scalp care composition, which comprises a bright cola seed extract and an inonotus obliquus extract; based on 100% of the total mass of the anti-hair loss scalp care composition,

the content of the extract of the cola nut seeds is 0.01-99.99%; the content of Inonotus obliquus extract is 0.01-99.99%.

The anti-hair loss scalp care composition according to the present invention, wherein the preparation method of the bright cola seed extract comprises a step of extracting with a solvent.

The anti-hair loss scalp care composition according to the present invention, wherein the preparation method of the inonotus obliquus extract comprises a step of extraction with a solvent.

The present invention also provides a method for preparing the anti-hair loss scalp care composition according to the present invention, wherein the method for preparing comprises the step of mixing the extract of the seeds of the kola and the extract of the inonotus obliquus.

The invention also provides an application of the anti-hair loss scalp care composition in preparing scalp care products; preferably, the scalp care product is one or a combination of more than two of shampoo, hair conditioner, hair mask and scalp care essence.

The invention further provides scalp care essence which comprises the anti-hair loss scalp care composition.

The scalp care essence according to the present invention, wherein the content of the anti-hair loss scalp care composition is 0.15 to 20% based on 100% of the total mass of the scalp care essence.

The scalp care essence according to the present invention further comprises one or a combination of two or more of a preservative, a pH adjustor, a thickener, and a solvent.

The scalp care essence according to the present invention, wherein the preservative is contained in an amount of 0.1 to 1% based on 100% by weight of the total scalp care essence; the content of the pH regulator is 0.01-0.5%; the content of the thickener is 0.05-1%; the content of the solvent is 77.5-99%.

The invention further provides a preparation method of the scalp care essence, which comprises the step of mixing the components of the scalp care essence.

ADVANTAGEOUS EFFECTS OF INVENTION

The raw materials of the hair loss prevention scalp care composition of the invention are easy to obtain, and the hair loss prevention effect is excellent.

The care essence can directly act on scalp and has excellent alopecia preventing effect.

The preparation method of the hair loss prevention scalp care composition and the hair loss prevention scalp care essence is simple and easy to implement, raw materials are easy to obtain, and the hair loss prevention scalp care composition and the hair loss prevention scalp care essence are suitable for mass production.

Detailed Description

The following describes the present invention in detail. The following description of the technical features is based on the representative embodiments and specific examples of the present invention, but the present invention is not limited to these embodiments and specific examples. It should be noted that:

in the present specification, the numerical range indicated by the term "numerical value a to numerical value B" means a range including the end point numerical value A, B.

In the present specification, unless specifically stated otherwise, "a plurality" of "a plurality of" etc. means a numerical value of 2 or more.

In this specification, the terms "substantially", "substantially" or "substantially" mean that the error is less than 5%, or less than 3% or less than 1% compared to the relevant perfect or theoretical standard.

In the present specification, "%" means mass% unless otherwise specified.

In the present specification, the meaning of "can" includes both the meaning of performing a certain process and the meaning of not performing a certain process.

In this specification, "optional" or "optionally" means that the subsequently described event or circumstance may or may not occur, and that the description includes instances where the event occurs and instances where it does not.

Reference throughout this specification to "some specific/preferred embodiments," "other specific/preferred embodiments," "an embodiment," and so forth, means that a particular element (e.g., feature, structure, property, and/or characteristic) described in connection with the embodiment is included in at least one embodiment described herein, and may or may not be present in other embodiments. In addition, it is to be understood that the elements may be combined in any suitable manner in the various embodiments.

In the present specification, the "water" may be deionized water, double distilled water, ion-exchanged water, reverse osmosis water, purified water, or other water that can be used in the cosmetic field.

The invention provides an anti-hair loss scalp care composition, which comprises a bright cola seed extract and an inonotus obliquus extract; the content of the extract of the bright cola seeds is 0.01-99.99% based on 100% of the total mass of the hair loss prevention scalp care composition; the content of Inonotus obliquus extract is 0.01-99.99%.

The hair loss preventing scalp care composition of the present invention has excellent hair loss preventing effect.

Extract of cola nut

The cola is a plant of the family Sterculiaceae (Sterculiaceae). Evergreen arbor, about 10 meters in height. She Husheng, oval. The flower axillary grows without petals, is dicotyledon, has 4-5 starburst bone-shaped fruits on the top end of the flower stalk, has 8-10 cm length, has green peel and contains hard white or pink seeds. The main ingredients of the beverage comprise caffeine, and trace amount of theobromine (theobromine), essential oil, sugar, and cola alkali.

The invention can prevent alopecia by using the extract of the fruit seeds of the cola.

In some specific embodiments, in the present invention, the preparation method of the extract of the kola nut includes a step of extraction using a solvent, preferably, the solvent may be water, an alcohol solvent, etc., and in consideration of the efficacy of the extract of the kola nut, the extraction is preferably performed using water.

Further, in the present invention, the preparation method of the extract of cola glabra seed comprises the steps of:

pulverizing the bright cola seeds, and leaching in a solvent to obtain an extracting solution;

concentrating and drying the extract to obtain the bright cola seed extract.

Further, in the preparation of the extract of the kola nut, the temperature of the solvent may be 80-90 ℃, the number of times of extraction may be 2-6, each time of extraction may be 2-6 hours, and the extracts may be combined after the completion of the extraction. The amount of the solvent to be added is not particularly limited, and may be generally 2 to 6 times that of the bright cola seeds.

In addition, the particle size after crushing the light cola seeds can be 80-100 mesh. In carrying out leaching, ultrasonic-assisted vibration leaching may be employed in view of extraction efficiency.

Further, in the present invention, the content of the extract of the bright cola seeds is 0.01 to 99.99%, preferably 20 to 99.99%, based on 100% by mass of the total weight of the hair loss preventing scalp care composition, for example: 1%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, etc.; the cola nut extract has wide application in beverage, and can accelerate blood circulation to help fatigue recovery. The inventors found that applying the extract of kola seed as an active scalp improves scalp blood circulation and thus improves the health of hair follicles to achieve the effect of reducing hair loss.

Inonotus obliquus extract

Inonotus obliquus, latin's name Inonotus obliquus (Fr.) Pilat, is a wood rot fungus growing in the frigid zone, belonging to the genus Fungium, basidiomycetes, polyporales, polyporaceae, and Phlebopus. Inonotus obliquus contains a large amount of plant fiber polysaccharide, and is reported to have separated tannins, steroids, alkaloids, melanin, low molecular polyphenols and lignin. Inonotus obliquus is a rare and rare medicinal fungus, and animal experiments and clinical experiments show that the Inonotus obliquus has no toxic or side effect, has the effects of resisting cancer, resisting virus, resisting aging, reducing blood pressure, reducing blood sugar and reviving immunity, and can improve and prevent allergic cortex and the like.

The invention can produce synergistic effect with the extract of the cola lanuginose seeds by using the extract of the inonotus obliquus, thereby further playing the role of preventing alopecia.

In some specific embodiments, in the present invention, the preparation method of the inonotus obliquus extract includes a step of extraction with a solvent, preferably, the solvent may be water, an alcohol solvent, etc., and in consideration of the efficacy of the inonotus obliquus extract, the extraction is preferably performed using water.

Further, in the present invention, the preparation method of the inonotus obliquus extract comprises the steps of:

pulverizing Inonotus obliquus, and leaching in solvent to obtain extractive solution;

concentrating and drying the extract to obtain the inonotus obliquus extract.

Further, in preparing the inonotus obliquus extract, the temperature of the solvent may be 60-80 ℃, the number of times of extraction may be 3-7, each time of extraction may be 1-5 hours, and the extracts may be combined after the completion of extraction. The amount of the solvent to be added is not particularly limited, but may be generally 1 to 5 times as large as that of the inonotus obliquus raw material.

In addition, the particle size after pulverization of Inonotus obliquus may be 80-100 mesh. In carrying out leaching, ultrasonic-assisted vibration leaching may be employed in view of extraction efficiency.

Further, in the present invention, the inonotus obliquus extract is contained in an amount of 0.01 to 99.99%, preferably 0.01 to 80%, based on 100% by mass of the total weight of the alopecia preventing scalp care composition, for example: 1%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, etc.; the inventor discovers that the inonotus obliquus extract is used in scalp care cosmetics, has good anti-inflammatory, relieving and moisturizing effects, can improve the problems of scalp dryness, red itching and the like, slow down scalp aging, and maintain the healthy state of the scalp.

Preparation method

The first aspect of the present invention also provides a method for preparing the anti-hair loss scalp care composition according to the present invention, the method comprising the step of mixing the extract of kola seed and the extract of inonotus obliquus.

Specifically, the extract of the kola seed and the extract of the inonotus obliquus may be mixed in a solvent. The mixing method is not particularly limited, and may be a mixing method commonly used in the art. For example: the extract of the seeds of the cola lanuginosa can be dissolved in a solvent to obtain a first mixed solution; and adding the inonotus obliquus extract into the first mixed solution to obtain the hair loss prevention scalp care composition. The inonotus obliquus extract can be dissolved in a solvent to obtain a first mixed solution; and adding the extract of the bright cola seeds into the first mixed solution to obtain the hair loss prevention scalp care composition. Optionally mixing the extract of cola nut seed and the extract of Inonotus obliquus, and adding solvent to dissolve the two.

Further, the temperature of the mixing is not particularly limited, and the mixing may be generally performed at room temperature. In the present invention, the room temperature may generally refer to 10 to 40 ℃.

< second aspect >

A second aspect of the present invention provides the use of an anti-hair loss scalp care composition according to the first aspect of the present invention in the preparation of a scalp care product; preferably, the scalp care product is one or a combination of more than two of shampoo, hair conditioner, hair mask and scalp care essence.

The anti-hair loss scalp care composition can play an excellent role in preventing hair loss when applied to scalp care products.

Further, the invention also provides a scalp care essence comprising the anti-hair loss scalp care composition according to the first aspect of the invention.

In some specific embodiments, the anti-hair loss scalp care composition is present in an amount of 0.15-20%, based on 100% total mass of the scalp care concentrate, for example: 1%, 3%, 5%, 7%, 8%, 9%, 11%, 13%, 15%, 17%, 18%, 19%, etc. When the content of the anti-hair loss scalp care composition is 0.15-20%, the effects of the scalp care essence can be effectively exerted.

Specifically, in the present invention, the scalp care essence further comprises one or a combination of two or more of a preservative, a pH adjuster, a thickener, and a solvent.

In the present invention, the scalp care essence of the present invention may further comprise a thickener in view of easier realization of application. The thickener is not particularly limited, and may be some commonly used in the art. Specifically, the thickener comprises one or more of carbomer, xanthan gum, sclerotium gum, guar gum, acrylic acid (ester) copolymer, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, gellan gum, sodium alginate, sodium polyacrylate and hydroxyethyl cellulose.

In the present invention, the thickener is contained in an amount of 0.05 to 1% by weight based on the total mass of the scalp care essence, for example: 0.08%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, etc. When the addition amount of the thickener is 0.05 to 1%, the product stability is excellent, the product is not thick and the spreadability is excellent.

In the present invention, the scalp care essence of the present invention may further comprise a pH adjuster in order to provide the scalp care essence with an appropriate pH value. The pH adjuster is not particularly limited, and may be some commonly used in the art. Specifically, the pH adjuster may include citric acid and one or a combination of two or more of sodium citrate, sodium hydroxide, potassium hydroxide, triethanolamine, aminomethylpropanol, arginine, and lactic acid.

The content of the pH adjuster is 0.01 to 0.5% based on 100% of the total mass of the scalp care essence, for example: 0.05%, 0.08%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, etc.; when the addition amount of the pH regulator is 0.01-0.5%, the pH value of the product is proper, and the product is more beneficial to skin absorption.

In the invention, the preservative comprises one or more than two of phenoxyethanol, sodium benzoate, ethylhexyl glycerol, methylparaben, 1, 2-hexanediol, chlorphenicol, methylisothiazolinone, potassium sorbate and benzyl alcohol. The content of the preservative is 0.1-1% based on 100% of the total mass of the scalp care essence.

Further, in order to better achieve the use of the scalp, the scalp care essence of the present invention may be added with an appropriate solvent, specifically, the content of the solvent is 77.5 to 99%, for example, 78%, 80%, 82%, 85%, 88%, 90%, 92%, 95%, 98%, etc. The solvent is not particularly limited, and may be some solvents commonly used in the art, for example: one or more of ethanol, propylene glycol, butylene glycol, pentylene glycol, glycerol, dipropylene glycol, water, etc.

The invention also provides a preparation method of the scalp care essence, which comprises the step of mixing the components of the scalp care essence.

Specifically, the preparation method comprises the following steps:

1) Putting the solvent into a reaction kettle at room temperature;

2) Adding the extract of the cola seeds into a reaction kettle at room temperature, stirring until the extract is uniformly dissolved, and adding the extract of the inonotus obliquus into the reaction kettle at room temperature, stirring until the extract is uniformly dissolved;

4) Adding the thickener into a reaction kettle at room temperature, and stirring until the thickener is uniformly dissolved;

5) And (3) adding the preservative and the pH regulator into a reaction kettle at room temperature, stirring and dissolving uniformly to obtain the skin care essence.

Examples

Embodiments of the present invention will be described in detail below with reference to examples, but it will be understood by those skilled in the art that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.

In the examples and comparative examples, the extract of the bright cola nut was prepared by the following method: pulverizing the raw material of the bright cola seeds to 80-100 meshes, adding 4 times of purified water at about 85 ℃ for leaching for 4 times by using ultrasonic vibration, filtering for 4 hours each time, combining the filtrates, concentrating and drying the filtrate to obtain powder, and obtaining the bright cola seed extract.

In examples and comparative examples, inonotus obliquus extract was prepared by the following method: pulverizing dried Inonotus obliquus raw material to 80-100 mesh, adding 3 times of purified water at 70deg.C at room temperature, extracting with ultrasonic vibration for 5 times, each for 3 hr, filtering, mixing filtrates, concentrating, lyophilizing to obtain powder, and obtaining Inonotus obliquus extract.

Examples 1 to 5

According to the mass content in table 1, scalp care essence was prepared as follows.

1) Adding solvent purified water into a reaction kettle at room temperature;

2) Adding the extract of the kola seed into a reaction kettle at room temperature, stirring until the extract is dissolved uniformly, and adding the extract of the inonotus obliquus into the reaction kettle at room temperature, stirring until the extract is dissolved uniformly, so as to obtain a hair loss prevention scalp care composition solution;

4) Adding a thickening agent xanthan gum into a reaction kettle at room temperature, and stirring until the thickening agent xanthan gum is uniformly dissolved;

5) And (3) adding the preservative phenoxyethanol and the pH regulator citric acid into a reaction kettle at room temperature, stirring and dissolving uniformly to obtain the scalp care essence.

TABLE 1

Comparative examples 1 to 3

Scalp care essence was prepared according to the same method as examples 1 to 5 according to the mass contents in table 2.

TABLE 2

Performance testing

1. 60 comb method test

1. The subjects can not shampoo within 48+/-4 hours before each visit, and can not comb the hair in the morning of visiting day;

2. after each time the test mechanism is adapted to the environment, the same trained technician adopts combs (see 2.3.4) with the same specification, and the combs are uniformly combed for 60 times (30 times each from left to right) according to the sequence from left front to left back and right front to right back;

3. the hair that was shed was collected and counted.

The scalp care essence of example 1, example 2, example 3, example 4, example 5, comparative example 1, comparative example 2 and comparative example 3 is used for each time, and 20 drops of the essence are used for scalp application and massage for 1-3 minutes each time. The test of 60 times comb method is carried out for the test subjects before the use of the product and 4 weeks, 8 weeks and 12 weeks after the use of the product, so as to record the number of alopecia. The test statistics are shown in table 3 below:

TABLE 3 average number of alopecia

As can be seen from table 1, examples 1,2, 3, 4, and 5 all have remarkable anti-hair loss effects, and the effect of reducing hair loss with longer use time is more remarkable; in combination with comparative examples 1,2 and 3, 5% of Inonotus obliquus extract or 5% of clear cola seed extract has a certain anti-drop effect. And, from example 1 and comparative example 1; example 2 and comparative example 2; as is apparent from example 3 and comparative examples 1 and 2, when the inonotus obliquus extract and the kola seed extract were used together, they had a synergistic effect.

2. Rate of reduction of 12 weeks of alopecia

According to the test results in the performance test 1, the reduction rate of the perialopecia was calculated, specifically according to the following formula, and the results are shown in the following table 4:

perialopecia reduction rate/% = (number of hair loss at 0 week-number of hair loss at 12 weeks)/number of hair loss at 0 week

TABLE 4 reduction rate of alopecia in 12 weeks (%)

As can be seen from table 2, the test results of example 3, example 4, example 5 and comparative example 3 and comparative example 1, comparative example 2 show that the anti-drop effect of the inonotus obliquus extract compounded with the extract of the bright cola seeds is effective and obviously better than that of the inonotus obliquus extract or the extract of the bright cola seeds which is 5% of the extract of the inonotus obliquus alone; in conclusion, the inonotus obliquus extract or the cola bright seed extract has a certain anti-drop effect, and the combination of the inonotus obliquus extract and the cola bright seed extract has a synergistic effect, so that the anti-drop effect is more excellent.

It should be noted that, although the technical solution of the present invention is described in specific examples, those skilled in the art can understand that the present invention should not be limited thereto.

The foregoing description of embodiments of the invention has been presented for purposes of illustration and description, and is not intended to be exhaustive or limited to the embodiments disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the various embodiments described. The terminology used herein was chosen in order to best explain the principles of the embodiments, the practical application, or the technical improvements in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.

Claims

1. An anti-hair loss scalp care composition, characterized by comprising an extract of kola nut and an extract of inonotus obliquus; based on 100% of the total mass of the anti-hair loss scalp care composition,

the content of the extract of the cola nut seeds is 0.01-99.99%; the content of Inonotus obliquus extract is 0.01-99.99%;

the preparation method of the bright cola seed extract comprises the following steps:

pulverizing the bright cola seeds, and then placing the pulverized bright cola seeds in a solvent for leaching to obtain a first extract;

concentrating and drying the first extract to obtain a bright cola seed extract;

the preparation method of the inonotus obliquus extract comprises the following steps:

pulverizing Inonotus obliquus, and leaching in solvent to obtain second extractive solution;

concentrating and drying the second extract to obtain the inonotus obliquus extract.

2. A method of preparing an anti-hair loss scalp care composition according to claim 1, characterized in that the method comprises the step of mixing a kola seed extract and a inonotus obliquus extract.

3. Use of an anti-hair loss scalp care composition according to claim 1 in the preparation of a scalp care product.

4. The use according to claim 3, wherein the scalp care product is any one of shampoo, conditioner, hair mask, scalp care essence.

5. Scalp care essence characterized by comprising the anti-hair loss scalp care composition according to claim 1.

6. The scalp care essence according to claim 5, wherein the content of the anti-hair loss scalp care composition is 0.15 to 20% based on 100% of the total mass of the scalp care essence.

7. The scalp care concentrate according to claim 5 or 6, further comprising one or a combination of two or more of a preservative, a pH adjuster, a thickener, and a solvent.

8. The scalp care essence according to claim 7, wherein the content of the preservative is 0.1 to 1% based on 100% of the total mass of the scalp care essence; the content of the pH regulator is 0.01-0.5%; the content of the thickener is 0.05-1%; the content of the solvent is 77.5-99%.

9. A method of preparing a scalp care concentrate according to any one of claims 5 to 8 comprising the step of mixing the components of the scalp care concentrate.