CN114748576A - Medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste and preparation method thereof - Google Patents

Medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste and preparation method thereof Download PDF

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CN114748576A
CN114748576A CN202210534322.9A CN202210534322A CN114748576A CN 114748576 A CN114748576 A CN 114748576A CN 202210534322 A CN202210534322 A CN 202210534322A CN 114748576 A CN114748576 A CN 114748576A
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CN114748576B (en
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栗明峰
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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to twenty medicinal and edible radix pseudostellariae and sea buckthorn paste and a preparation method thereof, wherein the twenty medicinal and edible radix pseudostellariae and sea buckthorn paste is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, the traditional Chinese medicine composition comprises radix polygonati officinalis, Chinese yam, liquorice, white hyacinth beans, endothelium corneum gigeriae galli, Chinese date, poria cocos, radix pseudostellariae, rehmannia glutinosa, oysters, dried tangerine peel, radish seeds, radix foeniculiae galli, sword beans, dark plum, emblic leafflower fruits, sweet almonds, sea-buckthorns, bunge cherry seeds and mulberries which are medicinal and edible raw material medicines, and the paste can be used for conditioning repeated constipation, diarrhea, dyspepsia, poor absorption and repeated upper respiratory tract infection caused by deficiency of congenital spleen and stomach of children and acquired weakness of spleen and can play a good conditioning role on sequelae (pharyngitis, hypertrophy of tonsil, hypertrophy of adenoids, allergic rhinitis and allergic tracheitis); moreover, the medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste has good taste, is easy to accept by children, has small side effect and is particularly suitable for children to take.

Description

Medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food and a preparation method thereof.
Background
The weakness of the spleen and the stomach of children is mainly manifested by yellow and waxy face, no bloody color, emaciation, constipation or diarrhea, poor appetite, and the condition of abdominal fullness and distention, indigestion, vigorous lung fire, repeated upper respiratory tract infection and the like after eating a little more. Weakness of the spleen and stomach of children is usually caused by congenital deficiency or acquired malnutrition. Wherein, the congenital reasons comprise premature birth of children, weakness of spleen and stomach of parents, and the like; acquired reasons include diet, such as raw and cold greasy food, improper feeding, food retention, etc.; in addition, some children who have got other diseases may not timely regulate the abdomen after the disease, which may also lead to a series of spleen and stomach weakness diseases.
At present, the children with stomach deficiency and spleen weakness can be generally conditioned by some Chinese patent medicines and physical therapy methods such as massage and moxibustion, but the inventor of the application finds that the existing treatment methods are generally too single in curative effect and poor in curative effect in medical practice, and in addition, the receptivity of the children in the age group needs to be fully considered for the administration of the children, so that the negative influence of the side effect of the medicine on the children needs to be reduced or avoided as much as possible.
Disclosure of Invention
The invention aims to provide twenty medicinal and edible radix pseudostellariae and sea buckthorn paste and a preparation method thereof, and solves the technical problems that the treatment effect for the weakness of spleen and stomach of children is poor in the prior art, and especially for children patients under the age of 5 years old, the curative effect cannot be considered, and meanwhile, the side effect cannot be reduced.
The invention relates to a traditional Chinese medical doctor of a chestnut pediatric clinic of Dongtian Naoku, Mengzhou, Henan province, specially attacks pediatrics, mainly treats the pediatric diseases including weakness of spleen and stomach of children, low resistance, repeated illness and the like, carries out medical treatment for many years, and collects and treats a large number of infantile cases with weakness of spleen and stomach.
In the long-term diagnosis and treatment process, the inventor has a profound understanding and thinking on the treatment and curative effects of various Chinese patent medicines and Chinese herbal prescriptions for conditioning the weakness of the spleen and the stomach of the child and the curative effects of traditional physical therapies such as massage and moxibustion, and finds that the traditional physical therapies such as the traditional Chinese patent medicines, the massage and the moxibustion have a single treatment effect on the weak stomach and the spleen of the child, and particularly have poor curative effects on sequelae caused by the weakness of the spleen and the stomach for a long time.
In addition, the gastrointestinal functions and physical conditions of children under 5 years old and children over 5 years old are generally obviously different, the state also provides the standard of 'judgment on growth conditions of children under 5 years old', the gastrointestinal functions of children under 5 years old are relatively fragile and have poor absorption capacity, and the prescription needs to fully consider and reduce the side effects on the children of the age group.
Therefore, by combining clinical experience and traditional Chinese medicine theories, the inventor develops a traditional Chinese medicine ointment capable of effectively regulating the deficiency of spleen and stomach of children, namely twenty medicinal and edible radix pseudostellariae and sea buckthorn ointment, and the ointment achieves the treatment effect and reduces the side effect on the children.
The first aspect of the present invention is:
the twenty-flavor radix pseudostellariae and sea buckthorn paste with the homology of medicine and food is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, wherein the traditional Chinese medicine composition comprises, by weight, 450-550 parts of radix polygonati officinalis, 350-450 parts of Chinese yam, 350-450 parts of liquorice, 350-450 parts of white hyacinth bean, 350-450 parts of endothelium corneum gigeriae galli, 450-550 parts of Chinese date, 450-550 parts of poria cocos, 350-450 parts of radix pseudostellariae, 350-450 parts of rehmannia, 350-450 parts of oyster, 350-450 parts of dried orange peel, 350-450 parts of semen raphani, 350-450 parts of radix foenigii, 550-650 parts of sword bean, 450-550 parts of dark plum fruit, 350-450 parts of emblic leafflower fruit, 550-650 parts of sweet almond, 350-450 parts of sea buckthorn, 350-450 parts of bunge cherry seed and 550-650 parts of mulberry.
Preferably, the traditional Chinese medicine composition comprises, by weight, 500 parts of polygonatum odoratum, 400 parts of Chinese yam, 400 parts of liquorice, 400 parts of white hyacinth bean, 400 parts of endothelium corneum gigeriae galli, 500 parts of Chinese date, 500 parts of poria cocos, 400 parts of radix pseudostellariae, 400 parts of rehmannia, 400 parts of oyster, 400 parts of dried orange peel, 400 parts of radish seed, 400 parts of ginseng, 600 parts of sword bean, 500 parts of dark plum, 400 parts of emblic leafflower fruit, 600 parts of sweet almond, 400 parts of sea buckthorn, 400 parts of bunge cherry seed and 600 parts of mulberry.
The second aspect of the present invention is:
the invention provides a preparation method of twenty medicinal and edible radix pseudostellariae and sea buckthorn paste in any one of the first aspect, which comprises the following steps:
(1) preparing a liquid medicine:
(1.1) preparing monarch drug liquid: preparing monarch drug liquid from the polygonatum, the Chinese date, the poria cocos and the dark plum in a monarch drug formula in the traditional Chinese medicine composition;
(1.2) preparing a ministerial drug liquid: the ministerial drug liquid medicine is prepared from Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea buckthorn and bunge cherry seed in the ministerial drug formula in the traditional Chinese medicine composition;
(1.3) preparing an adjuvant liquid medicine: preparing adjuvant liquid medicine from semen lablab album, endothelium corneum Gigeriae Galli, radix Pseudostellariae, rehmanniae radix, Concha Ostreae, and radix Adenophorae in adjuvant prescription of Chinese medicinal composition;
(1.4) preparing the liquid medicine of the medicines: preparing a liquid medicine of the guiding medicaments by using sword beans, sweet almonds and mulberries in a guiding medicament formula in the traditional Chinese medicine composition;
(2) the monarch drug liquid medicine, the ministerial drug liquid medicine, the adjuvant drug liquid medicine and the conductant drug liquid medicine prepared in the step (1) are placed in a cool place and are kept stand for a period of time for standby;
(3) mixing the monarch drug liquid medicine, the ministerial drug liquid medicine, the adjuvant drug liquid medicine and the conductant drug liquid medicine which are kept stand for standby in the step (2), decocting the mixed liquid medicine by adopting a small fire, evaporating and concentrating the mixed liquid medicine, continuously stirring the mixed liquid medicine at the same time, preventing coking, gradually forming the mixed liquid medicine into a thick paste, then adding a proper amount of maltose, decocting by using the small fire, continuously stirring and uniformly mixing, turning off the fire, taking out the mixture from a pot, and packaging in a medical medicine bottle.
Preferably, the preparation of the monarch drug liquid specifically comprises the following steps:
(1.1.1) soaking: cutting and cleaning polygonatum, Chinese date, poria cocos and dark plum in a monarch drug formula in the traditional Chinese medicine composition, putting the cut and cleaned monarch drug, adding 7500-8500 parts of cold water according to the same weight parts of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.1.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foam floating on the surface to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.1.3) merging the decocted liquid medicines, filtering for many times by using gauze after precipitation, and further removing impurities in the liquid medicines.
Preferably, the preparation of the ministerial drug liquid medicine specifically comprises the following steps:
(1.2.1) soaking: cutting and cleaning Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed in a ministerial medicine formula in the traditional Chinese medicine composition, putting the cut and cleaned Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed into a medicine decocting pot, adding 9100-11000 parts of cold water in parts by weight of the Chinese medicine composition, and soaking for 10-14 hours;
(1.2.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; decocting for the third time according to the same method for the second time, and then filtering and taking out the liquid medicine;
(1.2.3) merging the decocted liquid medicines, filtering for many times by using gauze after precipitation, and further removing impurities in the liquid medicines.
Preferably, the preparation of the adjuvant liquid medicine specifically comprises:
(1.3.1) soaking: chopping and cleaning white hyacinth beans, endothelium corneum gigeriae galli, radix pseudostellariae, rehmannia root, oyster and holothurian in an adjuvant drug formula in the traditional Chinese medicine composition, putting the cut white hyacinth beans, endothelium corneum gigeriae galli, radix pseudostellariae, rehmannia root, oyster and holothurian into a decoction pot, adding 7500-8500 parts of cold water according to the same weight parts of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.3.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.3.3) mixing the decocted liquid medicines, precipitating, and filtering with gauze for multiple times to further remove impurities in the liquid medicines.
Preferably, the preparation of the liquid medicine of the medicant specifically comprises:
(1.4.1) soaking: chopping and cleaning sword beans, sweet almonds and mulberries in a messenger medicine formula in the traditional Chinese medicine composition, putting the chopped sword beans, sweet almonds and mulberries into a medicine decocting pot, adding 11500-12500 parts of cold water according to the same weight parts of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.4.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; decocting for the third time according to the same method for the second time, and then filtering and taking out the liquid medicine;
(1.4.3) merging the decocted liquid medicines, precipitating, and then filtering for many times by using gauze to further remove impurities in the liquid medicines.
In the process of developing the twenty-ingredient radix pseudostellariae and sea buckthorn paste with homology of medicine and food, the inventor mainly bases on the theory of traditional Chinese medicine with homology of medicine and food, and because the components in the formula with homology of medicine and food can be used as food and can also be used as traditional Chinese medicinal materials with therapeutic effect, the formula of the traditional Chinese medicine with homology of medicine and food is safer than that of a pure traditional Chinese medicine, has small side effect and is suitable for children.
The theory of homology of medicine and food (also called as homology of medicine and food) has existed in Chinese traditional medicine since ancient times, and the theory is considered that: many foods are both foods and medicines, many foods can be used for medicines, many medicines can also be eaten, and the strict distinction between the foods and the medicines is difficult, so that the food therapy method is the basis of the theory of homology of medicine and food and the food therapy method. Wherein, the internal classic has a very excellent theory on food therapy, such as treating diseases with toxic materials, and removing six of the toxic materials; treating diseases with common toxicity, seven of them are removed; treating diseases with small toxicity, and removing eight of the medicines; no toxicity, ten remove nine; the food of the cereal, meat, fruit and vegetable can be eaten after the food is completely eaten, and the food can not hurt the body, which can be called the earliest food therapy principle.
The traditional Chinese medicine and pharmacology have the concept that the traditional Chinese medicine is as follows: all the traditional Chinese medicines can be eaten, but the difference in dosage is only, namely, the edible amount with large toxic effect is small, and the edible amount with small toxic effect is large. Therefore, strictly speaking, in traditional Chinese medicine, medicines and food are not classified, and are relatively speaking, medicines are food, and food is medicines; food has little side effect, and the medicine has great side effect, which is another meaning of 'homology of medicine and food'.
The pharmacological analysis of each component of the traditional Chinese medicine composition used by the medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste provided by the invention is as follows:
fragrant solomonseal rhizome: nourishing yin, moistening dryness, promoting fluid production, and quenching thirst. Can be used for treating yin injury of lung and stomach, cough due to dryness-heat, dry throat, thirst, and diabetes due to internal heat.
Rehmannia root: clearing away heat, promoting salivation, cooling blood, and stopping bleeding. Can be used for treating yin impairment due to febrile disease, crimson tongue, polydipsia, macula, eruption, hematemesis, epistaxis, and sore throat.
Chinese yam: invigorating spleen and stomach, promoting fluid production, benefiting lung, invigorating kidney, and arresting seminal emission. Can be used for treating spleen deficiency, anorexia, chronic diarrhea, lung deficiency, cough, asthma, deficiency heat, and diabetes.
Tuckahoe, poria cocos: induce diuresis and drain dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Dried orange peel: regulate qi to invigorate spleen, dry dampness and resolve phlegm. Can be used for treating fullness and distention of chest and abdomen, anorexia, vomiting, diarrhea, cough, and excessive phlegm.
Chinese date: tonify middle-jiao and Qi, nourish blood and soothe the nerves. Can be used for treating spleen deficiency, anorexia, asthenia, and loose stool.
Radish seed: promote digestion, relieve distension, direct qi downward and resolve phlegm. Can be used for treating food stagnation, abdominal distention and pain, constipation, stagnation, dysentery, phlegm stagnation, and cough and asthma.
Licorice root: invigorating spleen, regulating stomach function, and invigorating qi. Can be used for treating weakness of spleen and stomach, listlessness, and debilitation.
White hyacinth bean: to invigorate the spleen, resolve dampness, regulate the middle warmer and relieve summer heat. Can be used for treating weakness of spleen and stomach, anorexia, loose stool, summer-heat, dampness, vomiting and diarrhea, chest distress, and abdominal distention.
Endothelium corneum gigeriae galli: invigorating stomach and promoting digestion. Can be used for treating dyspepsia, emesis, dysentery, infantile malnutrition, and enuresis.
Radix pseudostellariae: replenishing qi to invigorate the spleen, promoting the production of body fluid and moistening the lung. Can be used for treating spleen deficiency, asthenia, deficiency of both qi and yin, spontaneous perspiration, thirst, and dry cough due to lung dryness.
Oyster shell: to strengthen the tranquilization, subdue yang, tonify yin, soften hardness and dissipate nodulation. Can be used for treating palpitation, insomnia, vertigo, and tinnitus.
The rhizome of holothuria: tonify middle-jiao and replenish qi. Can be used for treating diarrhea due to spleen deficiency and cough due to lung deficiency.
Cutting beans: it enters stomach and kidney meridians and warms middle energizer and lowers qi to stop hiccup. Can be used for treating singultus and emesis due to deficiency-cold.
Dark plum: enters liver, spleen, lung and large intestine meridians, astringes lung and intestine, promotes the production of body fluid, and relieves ascaris. Can be used for treating lung deficiency, chronic cough, chronic dysentery, intestine dryness, asthenia heat, diabetes, ascariasis, emesis, abdominal pain, and biliary ascariasis.
Emblic leafflower fruit: enters lung and stomach channels, clears heat and cools blood, promotes digestion, invigorates stomach, promotes the production of body fluid and quenches thirst. Can be used for treating blood heat and blood stasis, dyspepsia, abdominal distention, cough, pharyngalgia, and xerostomia.
Sweet almond: enter lung and large intestine meridians, dispel phlegm and relieve cough, relieve asthma and moisten intestines. It can be used for treating cough due to exogenous pathogenic factor, asthma, sore throat, and constipation due to intestinal dryness.
Sea-buckthorn: relieving cough, eliminating phlegm, promoting digestion, removing food stagnation, promoting blood circulation, and removing blood stasis. Can be used for treating cough, excessive phlegm, dyspepsia, and abdominal pain due to food stagnation.
The Chinese dwarf cherry seeds: it enters the large, spleen, intestine and small intestine meridians, and has the actions of moistening dryness, smoothing intestine, descending qi and inducing diuresis. Can be used for treating intestinal dryness due to consumption of body fluid, food stagnation, qi stagnation, abdominal distention, constipation, edema, tinea pedis, and dysuria.
Mulberry: enter heart, liver and kidney meridians, tonify blood, nourish yin, promote fluid production and moisten dryness. Can be used for treating vertigo, tinnitus, palpitation, insomnia, thirst due to body fluid consumption, thirst due to internal heat, and constipation due to blood deficiency.
The twenty traditional Chinese medicines, namely the polygonatum odoratum, the Chinese yam, the liquorice, the white hyacinth bean, the endothelium corneum gigeriae galli, the Chinese date, the poria cocos, the radix pseudostellariae, the rehmannia root, the oyster, the dried orange peel, the radish seed, the ginseng, the sword bean, the dark plum fruit, the emblic leafflower fruit, the sweet almond, the sea buckthorn, the bunge cherry seed and the mulberry, are medicinal and edible raw materials, and can regulate the spleen and stomach and reduce the side effect to the maximum extent.
Compared with the prior art, the invention has the beneficial effects that:
1. the twenty-taste radix pseudostellariae and sea buckthorn paste with homology of medicine and food is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, can condition spleen and stomach, has the effects of tonifying spleen and benefiting lung, can achieve double conditioning, and can be used for conditioning repeated constipation, diarrhea, dyspepsia, poor absorption and repeated upper respiratory tract infection caused by deficiency of the innate spleen and stomach and weakness of the acquired spleen and stomach of children and playing a good conditioning role on sequelae (pharyngitis, hypertrophy of tonsil, hypertrophy of adenoid, allergic rhinitis and allergic tracheitis); moreover, the twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food has good taste, is easy to accept by children, has small side effect and is particularly suitable for being taken by children.
2. The traditional Chinese medicine composition adopted by the medicinal and edible Chinese herbal medicine-common source twenty-flavor radix pseudostellariae-sea buckthorn paste comprises twenty medicinal and edible raw medicines of radix polygonati officinalis, Chinese yam, liquorice, white hyacinth bean, endothelium corneum gigeriae galli, Chinese date, poria cocos, radix pseudostellariae, rehmannia root, oyster, dried orange peel, radish seed, ginseng, sword bean, dark plum, emblic leafflower fruit, sweet almond, sea buckthorn, bunge cherry seed and mulberry.
3. In consideration of the characteristics of weak gastrointestinal function and poor absorption of children under 5 years old, the medicine is concentrated into ointment, and clinical application shows that the ointment has good treatment effect on spleen and stomach weakness and sequelae of children under 5 years old.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
The present invention will be described in detail with reference to examples, in which the following examples are carried out under the conditions of conventional conditions or conditions recommended by the manufacturer, and reagents or equipment used therefor are not indicated by the manufacturer, and are commercially available products. In the following examples, 1 part was 1 g.
Example 1:
the embodiment provides twenty-ingredient radix pseudostellariae and sea buckthorn paste with homology of medicine and food, which is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, wherein the traditional Chinese medicine composition comprises 450 parts by weight of radix polygonati officinalis, 350 parts by weight of Chinese yam, 350 parts by weight of liquorice, 350 parts by weight of white hyacinth bean, 350 parts by weight of endothelium corneum gigeriae galli, 450 parts by weight of Chinese date, 450 parts by weight of poria cocos, 350 parts by weight of radix pseudostellariae, 350 parts by weight of rehmannia glutinosa, 350 parts by weight of oyster, 350 parts by weight of dried orange peel, 350 parts by weight of semen raphani, 350 parts by weight of radix codonopsis pilosulae, 550 parts by weight of sword bean, 450 parts by weight of dark plum fruit, 350 parts by weight of emblic leafflower fruit, 550 parts by weight of sweet almond, 350 parts by weight of sea buckthorn, 350 parts by weight of bunge cherry seed and 550 parts by weight of mulberry.
The preparation method of the twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food in the embodiment comprises the following steps:
(1) preparing a liquid medicine:
(1.1) preparing monarch drug liquid: the monarch drug liquid is prepared by the polygonatum, the Chinese date, the tuckahoe and the dark plum in the monarch drug formula in the traditional Chinese medicine composition.
The preparation method of the monarch drug liquid comprises the following steps:
(1.1.1) soaking: 450 parts of polygonatum odoratum, Chinese date, poria cocos and dark plum in the monarch drug formula in the traditional Chinese medicine composition are cut and cleaned and then placed into a decoction pot, the decoction pot adopts a big copper pot, 7500 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition, and the traditional Chinese medicine composition is soaked for 10 hours.
(1.1.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foam floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; and carrying out third decoction according to the same method for the second decoction, and then filtering and taking out the liquid medicine.
(1.1.3) merging the decocted liquid medicines, filtering the liquid medicines for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(1.2) preparing a ministerial drug liquid: the ministerial liquid medicine is prepared from Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed in the ministerial formula of the traditional Chinese medicine composition.
The preparation of the ministerial drug liquid specifically comprises the following steps:
(1.2.1) soaking: 350 parts of Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea buckthorn and bunge cherry seed in the ministerial drug formula in the traditional Chinese medicine composition are cut, cleaned and then placed into a decoction pot, 9100 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition, and the Chinese medicine composition is soaked for 10 hours.
(1.2.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foam floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot for decoction again, decocting according to the same method as the first decoction until the water submerges the decoction dregs, and then filtering and taking out the liquid medicine; decocting for the third time according to the same method for the second time, and then filtering and taking out the liquid medicine;
(1.2.3) merging the decocted liquid medicines, filtering the liquid medicines for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(1.3) preparing an adjuvant liquid medicine: the liquid medicine is prepared from semen lablab album, endothelium corneum Gigeriae Galli, radix Pseudostellariae, rehmanniae radix, Concha Ostreae, and radix Adenophorae in adjuvant prescription of Chinese medicinal composition.
The preparation of the adjuvant liquid medicine specifically comprises the following steps:
(1.3.1) soaking: 350 parts of white hyacinth bean, endothelium corneum gigeriae galli, radix pseudostellariae, rehmannia root, oyster shell and radix pseudostellariae in the adjuvant drug formula in the traditional Chinese medicine composition are cut, cleaned and then placed into a decoction pot, and 7500 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition to soak for 10 hours.
(1.3.2) decocting for three times: boiling with strong fire, decocting with slow fire, keeping slightly boiling, stirring while decocting, removing foam floating on the surface to avoid overflow, decocting for 1.5 hr, filtering, and taking out the decoction; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.3.3) mixing the decocted liquid medicines, precipitating, and filtering with four layers of gauze for three times to further remove impurities in the liquid medicines.
(1.4) preparing the liquid medicine of the medicines: the liquid medicine is prepared from semen Canavaliae, semen Pruni Armeniacae and Mori fructus in the prescription of Chinese medicinal composition.
The preparation of the liquid medicine of the messenger drug comprises the following steps:
(1.4.1) soaking: 550 parts of sword bean, sweet almond and mulberry in the prescription of the traditional Chinese medicine composition are respectively cut and cleaned, then the mixture is put into a decoction pot, and 11500 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition for soaking for 10 hours.
(1.4.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foam floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.4.3) merging the decocted liquid medicines, filtering the liquid medicines for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(2) And (2) placing the monarch drug liquid medicine, the ministerial drug liquid medicine, the adjuvant drug liquid medicine and the conductant drug liquid medicine prepared in the step (1) in a cool place for standing for a period of time for later use. Standing for 5 to 8 days.
(3) Mixing the monarch drug liquid, the ministerial drug liquid, the adjuvant drug liquid and the conductant drug liquid which are kept stand for standby in the step (2), decocting the mixed liquid by adopting small fire, evaporating and concentrating the mixed liquid, continuously stirring the mixed liquid to prevent coking, gradually forming the mixed liquid into thick paste, adding a proper amount of maltose, decocting by using small fire, continuously stirring and uniformly mixing, turning off fire, taking out the mixture, and packaging in a medical bottle.
The added maltose is mainly used for improving the taste, so that the ointment is suitable for children to take, and meanwhile, the maltose also has the effects of tonifying spleen and benefiting qi.
Example 2:
the embodiment provides medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste, which is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, wherein the traditional Chinese medicine composition comprises, by weight, 500 parts of radix polygonati officinalis, 400 parts of Chinese yam, 400 parts of liquorice, 400 parts of white hyacinth bean, 400 parts of endothelium corneum gigeriae galli, 500 parts of Chinese date, 500 parts of poria cocos, 400 parts of radix pseudostellariae, 400 parts of rehmannia, 400 parts of oyster, 400 parts of dried orange peel, 400 parts of semen raphani, 400 parts of radix codonopsis pilosulae, 600 parts of sword bean, 500 parts of dark plum fruit, 400 parts of emblic leafflower fruit, 600 parts of sweet almond, 400 parts of sea buckthorn, 400 parts of bunge cherry seed and 600 parts of mulberry.
The preparation method of the twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food in the embodiment comprises the following steps:
(1) preparing a liquid medicine:
(1.1) preparing monarch drug liquid: the preparation method comprises the steps of cutting and cleaning polygonatum, Chinese date, poria cocos and dark plum in a monarch drug formula in the traditional Chinese medicine composition, soaking, decocting and filtering to obtain monarch drug liquid.
The preparation method of the monarch drug liquid comprises the following steps:
(1.1.1) soaking: 500 parts of polygonatum odoratum, Chinese date, poria cocos and dark plum in the monarch drug formula in the traditional Chinese medicine composition are cut, cleaned and then placed into a drug-decocting pot, the drug-decocting pot adopts a big copper pot, 8000 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition, and the traditional Chinese medicine composition is soaked for 12 hours.
(1.1.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 2 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; and carrying out third decoction according to the same method for the second decoction, and then filtering and taking out the liquid medicine.
(1.1.3) merging the decocted liquid medicines, filtering the liquid medicines for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(1.2) preparing a ministerial drug liquid: chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed in a ministerial drug formula in the traditional Chinese medicine composition are cut, cleaned, soaked, decocted and filtered to obtain a ministerial drug liquid.
The preparation of the ministerial drug liquid comprises the following specific steps:
(1.2.1) soaking: 400 parts of Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed in the ministerial drug formula in the traditional Chinese medicine composition are cut, cleaned and then placed in a decoction pot, and 9600 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition to soak for 12 hours.
(1.2.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 2 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot for decoction again, decocting according to the same method as the first decoction until the water submerges the decoction dregs, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.2.3) merging the decocted liquid medicines, filtering the liquid medicines for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(1.3) preparing an adjuvant liquid medicine: the white hyacinth bean, the endothelium corneum gigeriae galli, the radix pseudostellariae, the rehmannia root, the oyster and the radix pseudostellariae in the adjuvant prescription in the traditional Chinese medicine composition are cut, cleaned, soaked, decocted and filtered to obtain an adjuvant liquid medicine.
The preparation of the adjuvant liquid medicine specifically comprises the following steps:
(1.3.1) soaking: 400 parts of each of white hyacinth bean, chicken's gizzard-membrane, radix pseudostellariae, rehmannia root, oyster shell and holothurian in the adjuvant prescription of the traditional Chinese medicine composition are cut, cleaned and then placed into a decoction pot, 8000 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition, and the mixture is soaked for 12 hours.
(1.3.2) decocting for three times: boiling with strong fire, decocting with slow fire, keeping slightly boiling, stirring while decocting, removing foam floating on the surface to avoid overflow, decocting for 2 hr, filtering, and taking out the decoction; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.3.3) mixing the decocted liquid medicines, precipitating, and filtering with four layers of gauze for three times to further remove impurities in the liquid medicines.
(1.4) preparing the liquid medicine of the medicines: the medicinal liquid is prepared by cutting and cleaning semen Canavaliae, semen Pruni Armeniacae and Mori fructus in the Chinese medicinal composition, soaking, decocting, and filtering.
The preparation method of the liquid medicine comprises the following steps:
(1.4.1) soaking: 600 parts of sword bean, sweet almond and mulberry in a prescription of the traditional Chinese medicine composition are cut, cleaned and then placed into a decoction pot, and 12000 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition for soaking for 12 hours.
(1.4.2) decocting for three times: boiling with strong fire, decocting with slow fire, keeping slightly boiling, stirring while decocting, removing foam floating on the surface to avoid overflow, decocting for 2 hr, filtering, and taking out the decoction; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; decocting for the third time according to the same method for the second time, and then filtering and taking out the liquid medicine;
(1.4.3) merging the decocted liquid medicines, filtering the liquid medicines for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(2) And (2) placing the monarch drug liquid medicine, the ministerial drug liquid medicine, the adjuvant drug liquid medicine and the conductant drug liquid medicine prepared in the step (1) in a cool place for standing for a period of time for later use. Standing for 5 to 8 days.
(3) Mixing the monarch drug liquid, the ministerial drug liquid, the adjuvant drug liquid and the conductant drug liquid which are kept stand for standby in the step (2), decocting the mixed liquid by adopting small fire, evaporating and concentrating the mixed liquid, continuously stirring the mixed liquid to prevent coking, gradually forming the mixed liquid into thick paste, adding a proper amount of maltose, decocting by using small fire, continuously stirring and uniformly mixing, turning off fire, taking out the mixture, and packaging in a medical bottle.
Example 3:
the embodiment provides medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste, which is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, wherein the traditional Chinese medicine composition comprises 550 parts by weight of radix polygonati officinalis, 450 parts by weight of Chinese yam, 450 parts by weight of liquorice, 450 parts by weight of white hyacinth bean, 450 parts by weight of endothelium corneum gigeriae galli, 550 parts by weight of Chinese date, 550 parts by weight of poria cocos, 450 parts by weight of radix pseudostellariae, 450 parts by weight of rehmannia glutinosa, 450 parts by weight of oyster, 450 parts by weight of dried orange peel, 450 parts by weight of semen raphani, 450 parts by weight of radix foeniculiae gracilifoliae, 650 parts by weight of sword bean, 550 parts by weight of dark plum, 450 parts by weight of emblic leafflower fruit, 650 parts by weight of sweet almond, 450 parts by weight of sea buckthorn, 450 parts by weight of bunge kernel and 650 parts by weight of mulberry.
The preparation method of the twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food in the embodiment comprises the following steps:
(1) preparing a liquid medicine:
(1.1) preparing monarch drug liquid: the preparation method comprises the steps of cutting and cleaning polygonatum, Chinese date, poria cocos and dark plum in a monarch drug formula in the traditional Chinese medicine composition, soaking, decocting and filtering to obtain monarch drug liquid.
The preparation method of the monarch drug liquid comprises the following steps:
(1.1.1) soaking: 550 parts of polygonatum odoratum, Chinese date, poria cocos and dark plum in the monarch drug formula in the traditional Chinese medicine composition are cut and cleaned, and then the mixture is placed into a decoction pot, the decoction pot adopts a big copper pot, 8500 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition, and the traditional Chinese medicine composition is soaked for 14 hours.
(1.1.2) decocting for three times: boiling with strong fire, decocting with slow fire, keeping slightly boiling, stirring while decocting, removing foam floating on the surface to avoid overflow, decocting for 2.5 hr, filtering, and taking out the decoction; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; decocting for the third time according to the same method for the second time, and filtering to obtain medicinal liquid.
(1.1.3) merging the decocted liquid medicines, filtering for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(1.2) preparing a ministerial drug liquid: chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed in a ministerial drug formula in the traditional Chinese medicine composition are cut, cleaned, soaked, decocted and filtered to obtain a ministerial drug liquid.
The preparation of the ministerial drug liquid specifically comprises the following steps:
(1.2.1) soaking: 450 parts of yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed in the ministerial drug formula in the traditional Chinese medicine composition are cut, cleaned and then placed into a decoction pot, and 11000 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition for soaking for 14 hours.
(1.2.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foam floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot for decoction again, decocting according to the same method as the first decoction until the water submerges the decoction dregs, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.2.3) merging the decocted liquid medicines, filtering for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(1.3) preparing an adjuvant liquid medicine: the white hyacinth bean, the endothelium corneum gigeriae galli, the radix pseudostellariae, the rehmannia root, the oyster and the radix pseudostellariae in the adjuvant prescription in the traditional Chinese medicine composition are cut, cleaned, soaked, decocted and filtered to obtain an adjuvant liquid medicine.
The preparation of the adjuvant liquid medicine comprises the following steps:
(1.3.1) soaking: 450 parts of white hyacinth bean, endothelium corneum gigeriae galli, radix pseudostellariae, rehmannia root, oyster shell and radix pseudostellariae in the adjuvant drug formula in the traditional Chinese medicine composition are cut and cleaned, then the mixture is placed into a decoction pot, and 8500 parts of cold water is added into the decoction pot according to the same weight parts of the traditional Chinese medicine composition, and the mixture is soaked for 14 hours.
(1.3.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foam floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot for decoction again, decocting according to the same method as the first decoction until the water submerges the decoction dregs, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.3.3) mixing the decocted liquid medicines, precipitating, and filtering with four layers of gauze for three times to further remove impurities in the liquid medicines.
(1.4) preparing a liquid medicine: the medicinal liquid is prepared by cutting and cleaning semen Canavaliae, semen Pruni Armeniacae and Mori fructus in the Chinese medicinal composition, soaking, decocting, and filtering.
The preparation of the liquid medicine of the messenger drug comprises the following steps:
(1.4.1) soaking: 650 parts of sword bean, sweet almond and mulberry in a medicine formula in the traditional Chinese medicine composition are cut, cleaned and then placed into a medicine decocting pot, 12500 parts of cold water is added according to the same weight parts of the traditional Chinese medicine composition, and the medicine is soaked for 14 hours.
(1.4.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foam floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.4.3) merging the decocted liquid medicines, filtering the liquid medicines for three times by using four layers of gauze after precipitation, and further removing impurities in the liquid medicines.
(2) And (2) placing the monarch drug liquid medicine, the ministerial drug liquid medicine, the adjuvant drug liquid medicine and the conductant drug liquid medicine prepared in the step (1) in a cool place for standing for a period of time for later use. Standing for 5 to 8 days.
(3) Mixing the monarch drug liquid, the ministerial drug liquid, the adjuvant drug liquid and the conductant drug liquid which are kept stand for standby in the step (2), decocting the mixed liquid by adopting small fire, evaporating and concentrating the mixed liquid, continuously stirring the mixed liquid to prevent coking, gradually forming the mixed liquid into thick paste, adding a proper amount of maltose, decocting by using small fire, continuously stirring and uniformly mixing, turning off fire, taking out the mixture, and packaging in a medical bottle.
The administration mode of the twenty medicinal and edible radix pseudostellariae and sea buckthorn paste comprises the following steps:
is suitable for children under 5 years old, is orally taken for 6 milliliters once and twice a day, and is taken with boiled water; one treatment course is two months and two times a year. The conditioning is best in the spring and winter of a year.
The inventor provides clinical case statistical data, which comprise statistics of treatment effects of the twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food on children with weakness of spleen and stomach, and statistics of treatment effects of the medicaments in the reference group on children with weakness of spleen and stomach, wherein the twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food are the twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food in the embodiment 2.
The statistical data are as follows:
1. the data source:
156 children patients with spleen and stomach weakness of chestnut pediatric patients who are diagnosed in 1 month to 2022 years in 2021 are collected according to diagnosis standards of spleen and stomach weakness of children in < TCM > pediatrics >, and 78 children in a treatment group and a control group are respectively collected. Wherein, the treatment groups comprise 40 men and 38 women; age 1-5 years, mean age 3.21 years; the disease course is 0.2-1.3 years old, and the average disease course is 0.71 years; severity of the disease: severe 19, moderate 37, mild 22. The control group comprises 37 men and 41 women; age 1-5 years, mean age 3.43 years; the disease course is 0.1-1.2 years old, and the average disease course is 0.65 years; severity of the disease: severe 16, moderate 35, mild 27. No obvious statistical difference exists between the two groups of sex, age distribution, disease course and disease condition, and the two groups of sex, age distribution, disease course and disease condition have comparability.
2. The treatment method comprises the following steps:
the treatment group children adopt the twenty-flavor radix pseudostellariae sea buckthorn paste with homology of medicine and food, adopt different treatment courses according to the course of disease and the severity of the state of illness of the children patients, wherein the severe children with the course of disease more than 0.5 year continuously take 5 treatment courses; the severe children with the disease course less than 0.5 year continuously take the medicine for 4 courses of treatment; the children with moderate disease course longer than 0.5 years continuously take the medicine for 4 courses of treatment; the children with moderate disease course less than 0.5 year take 3 courses of treatment continuously; the mild children patients with disease course more than 0.5 year take continuously for 3 courses of treatment; the mild children with disease course less than 0.5 year take continuously for 2 courses.
The children patients in the control group adopt conventional spleen and stomach conditioning medicines, wherein spleen tonifying granules (Chinese standard medicine: Z43020453) are adopted for the children patients mainly with the symptoms of abdominal fullness and distention, poor appetite and loose stool, and the administration course of treatment is formulated according to the instruction; infant spleen strengthening powder (Chinese medicine standard: Z42021570) is adopted for infants who mainly have dyspepsia, anorexia, abdominal distention and increased defecation frequency, and a medication course is formulated according to the instruction; for children with constipation, anorexia, common cold and dysplasia, Wang Shi Bao Chi Wan (Chinese medicine standard character: Z32020646) is used, and the course of treatment is made according to the instruction.
3. The curative effect standard is as follows:
according to the 'traditional Chinese medicine pediatric disease syndrome diagnosis curative effect standard' in the 'traditional Chinese medicine syndrome diagnosis curative effect standard', the evaluation index of the curative effect of the weakness of the spleen and the stomach of the child is formulated, wherein the obvious effect is as follows: after the treatment course is finished, the symptoms related to the weakness of the spleen and the stomach disappear; the complexion is normal and the expression is vivid; good appetite, normal food intake and normal stool, and can be judged as clinical cure. The method has the following advantages: after the medication course is finished, symptoms related to weakness of the spleen and the stomach are improved; the complexion is improved, and the spirit is changed well; improving the indexes of appetite, food intake, stool, etc. And (4) invalidation: after the treatment course is finished, symptoms related to the weakness of the spleen and the stomach are not obviously improved.
4. The statistical results for the treatment and control groups are shown in table 1 below:
TABLE 1 statistical Table of the treatment effects of the treatment groups and the control group
Group of Number of cases Clinical cure Is effective Invalidation Total effective rate
Treatment group 78 46 30 2 97.4%
Control group 78 21 41 16 79.5%
As shown in Table 1, the total effective rate of the treatment group is 97.4%, and the total effective rate of the control group is 79.5%. The treatment effect of the treatment group is better than that of the control group.
Analysis of statistical results by the inventors:
the spleen-strengthening granules in the control group can be used for conditioning symptoms of weakness of the spleen and the stomach, abdominal fullness and distention, poor appetite and loose stool, but the spleen-strengthening granules cannot be used for conditioning repeated upper respiratory tract infection, and the weakness of the spleen and the stomach often causes low immunity of children patients and insufficient resistance easily causes tonsillitis. The infant spleen-tonifying powder can be used for conditioning dyspepsia, indigestion, abdominal distension and increased defecation frequency, but has no way of tonifying spleen and improving intelligence while conditioning the spleen and stomach. The Wang Shi Baochi pill can be used for regulating symptoms such as infantile malnutrition, phlegm syncope and infantile convulsion, cough and asthma with wheezy phlegm, milk and food deficiency, vomiting and diarrhea and fever, constipation, common cold in four seasons, weakness of spleen and stomach, dysplasia and the like, and also has curative effects on patients with gastrointestinal disorder and phlegm-food retardation, but the Wang Shi Baochi pill has no method for regulating constipation and diarrhea.
The twenty-flavor radix pseudostellariae and sea buckthorn paste with homology of medicine and food is suitable for being used under five years old, can be used for conditioning repeated constipation, diarrhea, dyspepsia, malabsorption and repeated upper respiratory infection caused by deficiency of the innate spleen and stomach and weakness of the acquired spleen and stomach of children, and can play a good conditioning role on sequelae (pharyngitis, tonsil hypertrophy, adenoid hypertrophy, allergic rhinitis and allergic tracheitis).
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. The medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste is characterized by being prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, wherein the traditional Chinese medicine composition comprises, by weight, 450-550 parts of radix polygonati officinalis, 350-450 parts of Chinese yam, 350-450 parts of liquorice, 350-450 parts of white hyacinth bean, 350-450 parts of endothelium corneum gigeriae galli, 450-550 parts of Chinese date, 450-550 parts of poria cocos, 350-450 parts of radix pseudostellariae, 350-450 parts of rehmannia, 350-450 parts of oyster, 350-450 parts of pericarpium citri reticulatae, 350-450 parts of semen raphani, 350-450 parts of radix foenigii, 550-650 parts of sword bean, 450-550 parts of dark plum, 350-450 parts of emblic leafflower fruit, 550-650 parts of sweet almond, 350-450 parts of sea buckthorn, 350-450 parts of bunge cherry seed and 550-650 parts of mulberry.
2. The medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste as claimed in claim 1, wherein the traditional Chinese medicine composition comprises 500 parts by weight of radix polygonati officinalis, 400 parts by weight of Chinese yam, 400 parts by weight of liquorice, 400 parts by weight of white hyacinth bean, 400 parts by weight of endothelium corneum gigeriae galli, 500 parts by weight of Chinese date, 500 parts by weight of poria cocos, 400 parts by weight of radix pseudostellariae, 400 parts by weight of rehmannia, 400 parts by weight of oyster, 400 parts by weight of dried orange peel, 400 parts by weight of semen raphani, 400 parts by weight of ginseng, 600 parts by weight of sword bean, 500 parts by weight of dark plum, 400 parts by weight of emblic leafflower fruit, 600 parts by weight of sweet almond, 400 parts by weight of sea buckthorn, 400 parts by weight of bunge cherry seed and 600 parts by weight of mulberry.
3. The preparation method of twenty medicinal and edible radix pseudostellariae and sea buckthorn paste as claimed in any one of claims 1-2, which is characterized by comprising the following steps:
(1) preparing a liquid medicine:
(1.1) preparing monarch drug liquid: preparing monarch drug liquid from the polygonatum, the Chinese date, the poria cocos and the dark plum in a monarch drug formula in the traditional Chinese medicine composition;
(1.2) preparing a ministerial drug liquid: the ministerial drug liquid medicine is prepared from Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea buckthorn and bunge cherry seed in the ministerial drug formula in the traditional Chinese medicine composition;
(1.3) preparing an adjuvant liquid medicine: preparing adjuvant liquid medicine from semen lablab album, endothelium corneum Gigeriae Galli, radix Pseudostellariae, rehmanniae radix, Concha Ostreae, and radix Adenophorae in adjuvant prescription of Chinese medicinal composition;
(1.4) preparing the liquid medicine of the medicines: preparing a medicated liquid from semen Canavaliae, semen Pruni Armeniacae and Mori fructus in the Chinese medicinal composition;
(2) the monarch drug liquid medicine, the ministerial drug liquid medicine, the adjuvant drug liquid medicine and the conductant drug liquid medicine prepared in the step (1) are placed in a cool place and are kept stand for a period of time for standby;
(3) mixing the monarch drug liquid, the ministerial drug liquid, the adjuvant drug liquid and the conductant drug liquid which are kept stand for standby in the step (2), decocting the mixed liquid by adopting small fire, evaporating and concentrating the mixed liquid, continuously stirring the mixed liquid to prevent coking, gradually forming the mixed liquid into thick paste, adding a proper amount of maltose, decocting by using small fire, continuously stirring and uniformly mixing, turning off fire, taking out the mixture, and packaging in a medical bottle.
4. The medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste as claimed in claim 3, wherein the monarch drug liquid is prepared by the following steps:
(1.1.1) soaking: cutting and cleaning polygonatum, Chinese date, poria cocos and dark plum in a monarch drug formula in the traditional Chinese medicine composition, putting the cut and cleaned monarch drug, adding 7500-8500 parts of cold water according to the same weight parts of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.1.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.1.3) merging the decocted liquid medicines, filtering for many times by using gauze after precipitation, and further removing impurities in the liquid medicines.
5. The medicinal and edible twenty-flavor radix pseudostellariae and sea buckthorn paste according to claim 3, wherein the ministerial medicine liquid is prepared by the following specific steps:
(1.2.1) soaking: cutting and cleaning Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed in a ministerial medicine formula in the traditional Chinese medicine composition, putting the cut and cleaned Chinese yam, liquorice, dried orange peel, radish seed, emblic leafflower fruit, sea-buckthorn and bunge cherry seed into a medicine decocting pot, adding 9100-11000 parts of cold water in parts by weight of the Chinese medicine composition, and soaking for 10-14 hours;
(1.2.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; decocting for the third time according to the same method for the second time, and then filtering and taking out the liquid medicine;
(1.2.3) merging the decocted liquid medicines, filtering for many times by using gauze after precipitation, and further removing impurities in the liquid medicines.
6. The twenty-flavor radix pseudostellariae and sea buckthorn paste as claimed in claim 3 being medicine and food homologous, wherein the preparation of the adjuvant liquid medicine specifically comprises:
(1.3.1) soaking: chopping and cleaning white hyacinth beans, endothelium corneum gigeriae galli, radix pseudostellariae, rehmannia, oysters and radix pseudostellariae in an adjuvant drug formula in the traditional Chinese medicine composition, putting the cut white hyacinth beans, endothelium corneum gigeriae galli, radix pseudostellariae, rehmannia, oysters and radix pseudostellariae into a decoction pot, adding 7500-8500 parts of cold water according to the same weight parts of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.3.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; decocting for the third time according to the same method for the second time, and then filtering and taking out the liquid medicine;
(1.3.3) mixing the decocted liquid medicines, precipitating, and filtering with gauze for multiple times to further remove impurities in the liquid medicines.
7. The twenty-ingredient radix pseudostellariae and sea buckthorn cream as claimed in claim 3, wherein the preparation of the liquid medicine of the messenger drug specifically comprises:
(1.4.1) soaking: chopping and cleaning sword beans, sweet almonds and mulberries in a messenger medicine formula in the traditional Chinese medicine composition, putting the chopped sword beans, sweet almonds and mulberries into a medicine decocting pot, adding 11500-12500 parts of cold water according to the same weight parts of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.4.2) decocting for three times: after soaking, carrying out first decoction, wherein during the first decoction, boiling with strong fire, then decocting with slow fire, keeping slightly boiling, stirring in time during the decoction, removing foams floating on the surface so as to prevent the liquid medicine from overflowing, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; during the second decoction, adding cold water into the decoction dregs in the decoction pot, decocting again, taking the water amount to submerge the decoction dregs as the standard, decocting according to the same method during the first decoction, and then filtering and taking out the liquid medicine; performing third decoction according to the same method of the second decoction, and then filtering and taking out the liquid medicine;
(1.4.3) merging the decocted liquid medicines, precipitating, and then filtering for many times by using gauze to further remove impurities in the liquid medicines.
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CN105327239A (en) * 2014-07-04 2016-02-17 浙江爱生药业有限公司 Traditional Chinese medicinal composition for treating children anorexia as well as preparation method and application of traditional Chinese medicinal composition
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