CN114748407A

CN114748407A - Traditional Chinese medicine mask for whitening skin and removing acne

Info

Publication number: CN114748407A
Application number: CN202210520797.2A
Authority: CN
Inventors: 金丽华; 胡德新
Original assignee: Second Affiliated Hospital of ZCMU
Current assignee: Second Affiliated Hospital of ZCMU
Priority date: 2022-05-12
Filing date: 2022-05-12
Publication date: 2022-07-15
Anticipated expiration: 2042-05-12
Also published as: CN114748407B

Abstract

The invention relates to a traditional Chinese medicine mask for whitening skin and removing acne, which is prepared from radix angelicae, rose, semen cuscutae, concha haliotidis, poria cocos, semen coicis, rhizoma typhonii, bletilla striata, radix ampelopsis, radix puerariae, edible tulip and radix bupleuri. The traditional Chinese medicine mask disclosed by the invention is simple in preparation method, wide in raw material medicine source, low in cost, free of toxic and side effects, and has remarkable curative effects of whitening, lightening spots, tendering skin, eliminating acnes and removing acne marks.

Description

Traditional Chinese medicine mask for whitening and removing acne

Technical Field

The invention relates to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine mask for whitening and removing acnes.

Background

With the improvement of living standard, people pay more and more attention to external image, and the white and flawless skin is not only healthy performance, but also pleasant and increases confidence. However, with various environmental problems such as strong radiation of electronic products, environmental pollution, aging of population, global temperature rise, etc., more and more people have skin pigment dysregulation diseases. According to investigation, 80% of Asian women seek fair and crystal skin; 70% of european women use whitening products to reduce and eliminate chloasma. Therefore, whitening cosmetics have a large market share.

Tyrosinase is in melanin corpuscles in melanocytes, and when stimulated by factors such as ultraviolet rays, emotion and pressure, the tyrosinase can activate and catalyze tyrosine in blood to generate oxidation reaction to generate gray DOPA (DOPA), and then generate black gray Dopaquinone (DQ), wherein the dopaquinone is polymerized to form melanin granules, and the melanin granules are transferred to the skin surface layer under the action of cell metabolism. The whole process is influenced by various enzymes such as tyrosinase, dopa tautomerase, DHICA oxidase, etc., and the transfer of melanin is also influenced by the morphology of black pigment cells. Therefore, there are several approaches to whitening: 1. inhibiting proliferation of melanocytes; 2. inhibiting the activity of the relevant enzyme to reduce the level of melanin synthesis; 3. preventing the transfer of melanin granules to horn cells; 4. the metabolism speed of melanin is accelerated; 5. reduce the acceleration of melanin formation caused by external stimuli such as oxygen free radicals and ultraviolet rays.

The emphasis in cosmetic research today is on finding safer, more effective skin whitening additives. At present, the main whitening additives on the market achieve the effect of whitening skin mainly through the following ways, namely inhibiting tyrosinase activity, such as bearberry bitter and kojic acid; secondly, the amount of tyrosinase, such as placental peptide, is reduced; third, antioxidant effect, such as vitamin C and its derivatives; fourthly, the activity of tyrosine lightening enzyme, such as vitamin E, is inhibited.

Acne inflammation is associated with the induction of an acne immune response by Propionibacterium acnes (p. Among them, inflammatory factors such as interleukin (IL-1 beta), tumor necrosis factor (TNF-alpha) and the like play an important role in the acne inflammatory reaction, and the content of the inflammatory factors is related to the severity of acne inflammation.

The acne-removing cosmetic takes the pathogenesis of acne as a basis, and inhibits the factors of acne origin to achieve the aim of removing acne. The first type is antimicrobial and anti-inflammatory, and the commonly used antibacterial components include zinc salt (zinc sulfate, zinc gluconate, zinc glycyrrhetate, zinc pyrithione), sulfur, azelaic acid, clove essential oil, rosemary essential oil, tea tree essential oil, propolis, capsaicin, antibacterial peptide, etc. The second type is sebum secretion inhibitor, such as sulfur, vitamin B3, nicotinamide, soybean isoflavone, etc.

However, most of common whitening and acne removing formulas adopt chemical synthetic preparations, so that the effect is limited, and the chemical synthetic preparations are easy to generate adverse side effects. Therefore, it is urgent to find whitening additives with better effect, safety, abundant resources and simple acquisition. At present, the Chinese herbal medicine plant components used as whitening agents and acne removing agents are a new trend of future cosmetic development, and products containing the Chinese herbal medicine components have environment-friendly, green and efficient whitening and acne removing effects.

The action mechanism of the facial mask comprises two aspects, on one hand, the facial mask can isolate outside air and pollution, improve skin temperature, expand skin pores, promote secretion and metabolism of sweat glands, discharge products of epidermal cell metabolism and accumulated grease, and enable functional components in the facial mask to permeate into horny layers, thereby achieving the purposes of cleaning, moisturizing, whitening, resisting wrinkles, removing acnes and the like. Another aspect is the removal of dirt, cellular metabolites and excess oil from the skin when the mask is peeled off after drying. Traditional Chinese medicine components with different effects are added into the mask, so that the effects of moisturizing, whitening, removing freckles, removing acnes and the like can be achieved. Although some natural traditional Chinese medicine facial mask products mainly having the effects of whitening and removing acnes appear in the current facial mask market, the traditional Chinese medicine facial masks have the defects of slow effect taking and limited effects of whitening and removing acnes, and still have wide market prospects.

Disclosure of Invention

The invention aims to provide a traditional Chinese medicine mask capable of effectively whitening and removing acnes.

In order to achieve the purpose, the invention adopts the following technical scheme:

the first aspect of the invention provides a traditional Chinese medicine mask for whitening skin and removing acne, which is prepared from radix angelicae, rose, semen cuscutae, concha haliotidis, poria cocos, semen coicis, rhizoma typhonii, bletilla striata, radix ampelopsis, radix puerariae, edible tulip and radix bupleuri.

Preferably, the traditional Chinese medicine mask is prepared from 1-30 parts by weight of radix angelicae, 1-30 parts by weight of rose, 5-30 parts by weight of semen cuscutae, 1-30 parts by weight of concha haliotidis, 5-40 parts by weight of poria cocos, 10-50 parts by weight of semen coicis, 1-30 parts by weight of rhizoma typhonii, 1-30 parts by weight of bletilla striata, 5-30 parts by weight of radix ampelopsis, 5-40 parts by weight of radix puerariae, 5-30 parts by weight of edible tulip and 1-30 parts by weight of radix bupleuri.

More preferably, the traditional Chinese medicine facial mask is prepared from 5-20 parts by weight of radix angelicae, 5-20 parts by weight of rose, 10-20 parts by weight of semen cuscutae, 5-20 parts by weight of concha haliotidis, 10-30 parts by weight of poria cocos, 20-40 parts by weight of semen coicis, 5-20 parts by weight of rhizoma typhonii, 5-20 parts by weight of bletilla striata, 10-20 parts by weight of radix ampelopsis, 10-30 parts by weight of radix puerariae, 10-20 parts by weight of edible tulip and 5-20 parts by weight of radix bupleuri.

Most preferably, the traditional Chinese medicine mask is prepared from 10 parts by weight of radix angelicae, 10 parts by weight of rose, 15 parts by weight of semen cuscutae, 10 parts by weight of concha haliotidis, 20 parts by weight of poria cocos, 30 parts by weight of semen coicis, 10 parts by weight of rhizoma typhonii, 10 parts by weight of bletilla striata, 15 parts by weight of radix ampelopsis, 20 parts by weight of radix puerariae, 15 parts by weight of edible tulip and 10 parts by weight of radix bupleuri.

Preferably, the traditional Chinese medicine mask further comprises honey.

The second aspect of the invention provides a preparation method of the traditional Chinese medicine mask, which comprises the following steps:

(1) weighing the angelica dahurica, rose, dodder, abalone shell, tuckahoe, coix seed, giant typhonium rhizome, bletilla striata, ampelopsis japonica, kudzu root, Indian iphigenia bulb and bupleurum root according to the prescription amount, mixing, grinding into fine powder by a machine, and sieving with a sieve of 300 meshes and 500 meshes;

(2) adding boiling water into the medicinal powder, blending into paste, cooling, adding appropriate amount of Mel, and mixing.

Preferably, the ultrafine powder in step (1) of the method is sieved by a 400-mesh sieve.

Preferably, honey is added in the step (2) of the method according to the amount of 1ml/5g of the medicinal powder.

The third aspect of the invention provides application of the traditional Chinese medicine mask in preparing cosmetics with whitening efficacy.

The fourth aspect of the invention provides application of the traditional Chinese medicine mask in preparation of cosmetics with acne removing efficacy.

The fifth aspect of the invention provides application of the traditional Chinese medicine mask in preparation of cosmetics for reducing IL-1 beta and/or TNF-alpha levels in serum.

The sixth aspect of the invention provides an application of the traditional Chinese medicine facial mask in preparing cosmetics for reducing the proliferation rate of melanoma cells and/or the total melanin synthesis amount in the melanoma cells.

Preferably, the melanoma cell is a B16 melanoma cell.

The common pharmacological effects of the traditional Chinese medicine raw materials selected by the invention in the field are as follows:

dahurian angelica root, radix Angelicae Dahuricae is warm in nature and pungent in flavor, and enters lung, spleen and stomach meridians. Radix Angelicae Dahuricae has effects of relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, relieving leukorrhagia, relieving swelling, expelling pus, dispelling pathogenic wind and relieving itching, and can be used for treating wind-cold type common cold, headache, toothache, rheumatalgia, nasosinusitis, leukorrhagia, skin sore, carbuncle and toxic swelling.

Rose flower, warm in nature, sweet and slightly bitter in taste, enters liver and spleen meridians. Flos Rosae Rugosae has effects of activating qi-flowing, resolving stagnation, regulating blood, and relieving pain, and can be used for treating liver and stomach qi pain, anorexia, emesis, menoxenia, and traumatic injury pain.

Tu Si Zi is neutral in nature, pungent and sweet in flavor, and enters liver, kidney and spleen meridians. Semen Cuscutae has effects of invigorating liver and kidney, stopping nocturnal emission, reducing urination, preventing miscarriage, improving eyesight, relieving diarrhea, dispelling pathogenic wind, and resolving macula, and can be used for treating nocturnal emission, dysuresia, enuresis, pollakisuria, vitiligo, etc.

Shi Jue Ming enters liver meridian because of its cold nature and salty taste. Concha Haliotidis has effects of suppressing hyperactive liver and subsiding yang, clearing liver and improving eyesight, and can be used for treating headache, giddiness, conjunctival congestion, nebula, blurred vision, and night blindness.

Poria, neutral in nature, sweet and bland in flavor, enters heart, lung, spleen and kidney meridians. Poria has effects in promoting diuresis, eliminating dampness, invigorating spleen, and calming heart, and can be used for treating edema, oliguria, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.

Coix seed, semen Coicis, with a cool nature, sweet and bland taste, enters spleen, stomach and lung meridians. Coicis semen has effects in promoting diuresis, eliminating dampness, invigorating spleen, relieving diarrhea, relieving arthralgia, expelling pus, removing toxic substance, and resolving hard mass, and can be used for treating edema, loempe, dysuresia, spleen deficiency diarrhea, damp arthralgia, contracture, pulmonary abscess, and intestinal abscess; wart, cancerous protuberance.

Baifuzi is warm in nature and pungent in flavor, and enters stomach meridian and liver meridian. Rhizoma Typhonii has effects of dispelling pathogenic wind phlegm, arresting convulsion, removing toxic substance, resolving hard mass, and relieving pain, and can be used for treating apoplexy phlegm stagnation, facial distortion, language handicap, phlegm syncope, headache, migraine, laryngopharyngitis, pharyngalgia, tetanus; it is used for external treatment of scrofula, subcutaneous nodule, and venomous snake bite.

Bletilla striata, also known as bletilla striata, is slightly cold in nature, bitter, sweet and astringent in flavor, and enters lung, liver and stomach meridians. Rhizoma Bletillae has effects of astringing for hemostasis, detumescence and promoting granulation, and can be used for treating traumatic hemorrhage, pyocutaneous disease, toxic swelling, and chapped skin.

Ampelopsis root, radix Ampelopsis, slightly cold in nature, bitter in taste. They enter heart and stomach meridians. Radix Ampelopsis has effects of clearing heat and detoxicating, resolving carbuncle and resolving hard mass, and can be used for treating carbuncle, cellulitis, furuncle, scrofula, scald due to water and fire, etc.

Kudzuvine root, neutral in nature, sweet and pungent in flavor, enters spleen and stomach meridians. Radix Puerariae has effects of relieving exterior syndrome, promoting eruption, promoting fluid production, and relieving diarrhea, and can be used for treating common cold, fever, aversion to cold, anhidrosis, and neck stiffness.

Pseudobulbus Cremastrae seu pleiones, with cold nature, sweet taste and slight pungent flavor, enters liver and spleen meridians. Pseudobulbus Cremastrae Seu pleiones has effects of clearing heat and toxic substances, eliminating phlegm and resolving hard mass, and can be used for treating carbuncle, furunculosis, lymphoid tuberculosis, and snake and insect bite.

Bupleurum root, radix bupleuri, with slightly cold nature, pungent and bitter taste, enters liver, gallbladder and lung meridians. Bupleuri radix, radix bupleuri, radix bupleuri, radix bupleuri, radix bupleuri, radix bupleuri, radix bupleuri, radix bupleuri, radix bupleuri, radix.

The invention has the positive and beneficial effects that:

1. the traditional Chinese medicine mask disclosed by the invention adopts natural traditional Chinese medicine raw materials, and is simple in preparation method, wide in raw material medicine source, low in cost and free of toxic and side effects.

2. The traditional Chinese medicine mask disclosed by the invention is scientific and reasonable in compatibility and formula, the raw medicinal materials are different in function and supplement each other, and the traditional Chinese medicine mask has remarkable curative effects of whitening, fading spots, tendering skin, eliminating acne and acne marks, and is less in adverse reaction during medication.

Detailed Description

The present invention will be further described with reference to the following examples, but the embodiments of the present invention are not limited thereto. The experimental procedures used in the following examples are all conventional procedures unless otherwise specified.

Example 1

Weighing 10g of angelica dahurica, 10g of rose, 15g of semen cuscutae, 10g of abalone shell, 20g of poria cocos, 30g of semen coicis, 10g of rhizoma typhonii, 10g of bletilla striata, 15g of ampelopsis japonica, 20g of radix puerariae, 15g of edible tulip and 10g of radix bupleuri, mixing, grinding into superfine powder by a machine, sieving by a 300-plus 500-mesh sieve, blending into paste by boiled water, cooling, adding 35ml of honey, and mixing uniformly to obtain the traditional Chinese medicine mask 1.

Example 2

Weighing 20g of angelica dahurica, 20g of rose, 15g of semen cuscutae, 10g of abalone shell, 20g of poria cocos, 10g of semen coicis, 10g of rhizoma typhonii, 10g of bletilla striata, 15g of radix ampelopsis, 20g of radix puerariae, 15g of edible tulip and 10g of radix bupleuri, mixing, grinding into superfine powder by a machine, sieving with a 300-mesh sieve and a 500-mesh sieve, blending into paste by using boiled water, cooling, adding 35ml of honey, and mixing uniformly to obtain the traditional Chinese medicine mask 2.

Example 3

Weighing 10g of radix angelicae, 10g of rose, 15g of semen cuscutae, 10g of abalone shell, 20g of poria cocos, 10g of semen coicis, 20g of rhizoma typhonii, 20g of bletilla striata, 15g of radix ampelopsis, 20g of radix puerariae, 15g of edible tulip and 10g of radix bupleuri, mixing, grinding into superfine powder by a machine, sieving with a 300-mesh sieve and a 500-mesh sieve, blending into paste by using boiled water, cooling, adding 35ml of honey, and mixing uniformly to obtain the traditional Chinese medicine mask 3.

Example 4

Weighing 10g of angelica dahurica, 10g of rose, 15g of semen cuscutae, 10g of abalone shell, 20g of poria cocos, 30g of semen coicis, 10g of rhizoma typhonii, 10g of bletilla striata, 25g of ampelopsis japonica, 10g of radix puerariae, 15g of edible tulip and 10g of radix bupleuri, mixing, grinding into superfine powder by a machine, sieving by a 300-plus 500-mesh sieve, blending into paste by boiled water, cooling, adding 35ml of honey, and mixing uniformly to obtain the traditional Chinese medicine mask 4.

Example 5

Weighing 20g of angelica dahurica, 10g of rose, 15g of semen cuscutae, 10g of abalone shell, 20g of poria cocos, 30g of semen coicis, 10g of rhizoma typhonii, 10g of bletilla striata, 15g of radix ampelopsis, 10g of radix puerariae, 15g of edible tulip and 10g of radix bupleuri, mixing, grinding into superfine powder by a machine, sieving with a 300-mesh sieve and a 500-mesh sieve, blending into paste by using boiled water, cooling, adding 35ml of honey, and mixing uniformly to obtain the traditional Chinese medicine mask 5.

The mask of embodiments 1-5 of the invention is used as follows: applying the traditional Chinese medicine facial mask on face, covering with preservative film on outer layer for moisturizing, scraping with scraping substrate after 20 min, and cleaning with warm water; the frequency of use is once a week.

Test example 1 treatment of p.acnes-induced ear inflammation in mice with the inventive drug

1. Test method

1.1 preparation of P.acnes suspension

Selecting P.acnes strain, culturing in brain heart infusion culture medium, inoculating, activating, proliferating, collecting bacterial colony, filtering, and adjusting bacterial concentration to 5 × 10¹²CFU/L. And preparing a P.acnes suspension for establishing an ear inflammation model of the P.acnes intradermal injection mouse.

1.2 preparation of decoction of Chinese medicinal materials

Respectively taking 175g of the traditional Chinese medicine composition of the embodiments 1-5 of the invention, mixing, grinding into superfine powder by a machine, sieving with a 300-mesh sieve and a 500-mesh sieve, adding 2 times of distilled water for decoction, filtering, and concentrating the filtrate into 1g/mL of traditional Chinese medicine decoction 1-5 for later use.

1.3 dosing regimens

70 healthy mice were selected and randomly divided into 7 groups (i.e., control group, model group, inventive example 1-5 groups), each of which was 10. Wherein, the control group is injected with 20 mu L of PBS solution in the middle of the bilateral auricle of the mouse intradermally, and the model group is injected with 20 mu L of P.acnes suspension in the middle of the bilateral auricle of the mouse intradermally; the modeling method of the embodiment groups 1 to 5 is the same as that of the model group, after 5 days of modeling, the embodiment groups smear Chinese medicine decoction 1 to 5 at the position of mouse pinna, 2 times a day with 0.1mL each time, continuously administer for 14d, kill the mouse 24h after the last administration, collect mouse serum, perform corresponding operation according to the instruction of the kit by an ELISA method, and detect the levels of IL-1 beta and TNF-alpha.

2. Test results

The contents of IL-1. beta. and TNF-alpha. in the serum of mice treated with the Chinese medicines of the experimental groups of the present invention are shown in Table 1 below.

TABLE 1 Effect of Chinese herbs in each test group of the present invention on IL-1. beta. and TNF-alpha. levels in mouse serum

Group of	IL-1β(ng/L)	TNF-ɑ(ng/L)
			Control group	42.82±5.87	15.31±2.69
Model set	147.27±11.03	57.32±4.73
			EXAMPLE 1 group	62.56±5.02	24.09±2.34
EXAMPLE 2 group	88.40±6.25	37.29±2.94
			EXAMPLE 3 group	84.56±8.21	38.95±2.76
EXAMPLE 4 group	92.42±7.98	42.41±3.98
			EXAMPLE 5 group	102.34±8.37	40.02±4.56

As can be seen from table 1 above, compared with the control group, the levels of IL-1 β and TNF-a in the serum of the model group mouse are significantly increased, confirming that the ear inflammation model of the p.acnes intradermal injection mouse is successfully constructed. Compared with a model group of mice, the groups 1 to 5 of the traditional Chinese medicine mask can reduce the IL-1 beta and TNF-alpha levels in the serum of the mice to different degrees, and the difference has statistical significance (P <0.05), so that the effective components of the traditional Chinese medicine mask have a definite anti-inflammatory effect on the ear inflammation of the mice induced by P.acnes, and the traditional Chinese medicine mask can be clinically used for treating acne and has the effect of removing acne. It is to be noted that the group of example 1 of the present invention most significantly reduced the levels of IL-1 β and TNF-a in the serum of mice, indicating that the composition of the present invention can produce excellent anti-inflammatory and acne-treating effects.

Test example 2 biological Effect of the present invention on melanoma cells of B16 mouse

1. Test method

1.1 preparation of decoction of Chinese medicinal materials

Respectively taking 175g of the traditional Chinese medicine composition of the embodiments 1-5 of the invention, mixing, grinding into superfine powder by a machine, sieving with a 300-mesh sieve and a 500-mesh sieve, adding 2 times of distilled water for decoction, filtering, and concentrating the filtrate into 1g/mL of traditional Chinese medicine decoction 1-5 for later use. It was diluted to 1mg/mL with distilled water before use.

1.2, B16 melanoma cell culture

Inoculating B16 melanoma cell into RPMI-1640 culture medium containing 10% fetal calf serum under aseptic condition, and culturing at 37 deg.C in carbon dioxide incubator with 5% CO₂Culturing in saturated humidity environmentThe liquid is changed every day. When the cells grow to reach 80% -90% of confluence, the cells are digested and passaged by 0.25% trypsin, and the cells are continuously cultured. Each experiment was performed on the same passaged cells at an initial inoculum cell concentration of 10 cells per ml of culture medium⁵About one cell.

1.3 detection of cell proliferation Rate by MTT colorimetric method

Taking B16 melanoma cells in exponential growth phase, digesting and dispersing to prepare single cell suspension, adjusting cell density to 1 × 10 per well⁴The cell density of each cell is inoculated in a 96-well plate, a new culture medium is replaced after the cells are cultured for 12 hours to be completely attached to the wall, 1-5 Chinese medicinal decoction with the concentration of 1mg/mL is added into each hole of each group in the examples 1-5, 10 holes are repeated for each test group, fresh culture solution is added into a control group to replace the Chinese medicinal decoction, 50 muL of MTT solution with the concentration of 1mg/mL is added into each hole after 48 hours of culture, the culture box is incubated for 4 hours, the culture medium and the MTT are discarded, 150 muL of DMSO is added into each hole to dissolve the residual MTT-formazan crystals, and the light absorption value of each hole under 570nm is measured by an enzyme labeling instrument after uniform mixing.

The cell proliferation rate was calculated according to the following formula: the cell proliferation rate is (experimental well OD value-blank well OD value)/(control well OD value-blank well OD value) × 100%.

1.4 Effect of the invention on the amount of melanin synthesized

Cell culture and experimental treatments were as in section 1.3. Culturing for 48h, allowing the cells to grow to 80% -90% and fuse, discarding the supernatant, washing with PBS for 2 times, digesting, collecting cells, adding 2mL in a centrifuge tube, diluting 20 μ L, centrifuging at 1500r/min for 10min, and discarding the supernatant. Adding 2mL of PBS for resuspension, adding 500 μ L of ethanol-ether mixture with volume ratio of 1:1, standing at room temperature for 30min, centrifuging at 3000r/min for 5min, discarding supernatant, adding 1mL of 1mol/L NaOH solution containing 10% DMSO, water bathing at 80 deg.C for 45min, and measuring absorbance at 405 nm.

The total melanin synthesis amount is the OD value of the experimental group/OD value of the control group × 100%.

2. Test results

The effect of the traditional Chinese medicine on the proliferation rate of B16 melanoma cells and the total melanin synthesis amount in each test group is shown in the following table 2.

TABLE 2 Effect of the inventive drugs on the proliferation rate of B16 melanoma cells and the total amount of melanin synthesis

Group of	Cell proliferation Rate (%)	Total amount of Melanin Synthesis (%)
			EXAMPLE 1 group	28.37±3.88	16.24±2.67
EXAMPLE 2 group	43.29±5.02	30.92±3.08
			EXAMPLE 3 group	48.01±5.28	32.46±2.90
EXAMPLE 4 group	50.42±4.91	40.57±3.89
			EXAMPLE 5 group	49.26±5.90	36.25±3.47

The results in table 2 show that the active ingredients of the traditional Chinese medicines in examples 1 to 5 of the present invention can significantly inhibit the growth of B12 melanocytes and significantly inhibit the synthesis of the total amount of melanin in B12 cells, and the inhibition effect of the group in example 1 on the total amount of cell proliferation and melanin synthesis is significantly stronger than that of the groups in examples 2 to 5. In conclusion, the active ingredients of the traditional Chinese medicine mask can simultaneously inhibit the generation of melanin from two aspects of reducing melanin synthesis places (namely inhibiting cell proliferation) and reducing the synthesis amount of melanin in cells, and the traditional Chinese medicine mask has the whitening effect clinically.

It is to be understood that the above-described embodiments of the present invention are merely illustrative of or explaining the principles of the invention and are not to be construed as limiting the invention. Therefore, any modification, equivalent replacement, improvement and the like made without departing from the spirit and scope of the present invention should be included in the protection scope of the present invention.

Claims

1. The traditional Chinese medicine mask for whitening and removing acnes is characterized by being prepared from radix angelicae, rose, semen cuscutae, concha haliotidis, poria cocos, semen coicis, rhizoma typhonii, bletilla striata, radix ampelopsis, radix puerariae, edible tulip and radix bupleuri.

2. The traditional Chinese medicine mask as claimed in claim 1, which is prepared from 1-30 parts by weight of radix angelicae, 1-30 parts by weight of rose, 5-30 parts by weight of semen cuscutae, 1-30 parts by weight of concha haliotidis, 5-40 parts by weight of poria cocos, 10-50 parts by weight of semen coicis, 1-30 parts by weight of rhizoma typhonii, 1-30 parts by weight of bletilla striata, 5-30 parts by weight of radix ampelopsis, 5-40 parts by weight of radix puerariae, 5-30 parts by weight of edible tulip and 1-30 parts by weight of radix bupleuri.

3. The traditional Chinese medicine mask as claimed in claim 2, which is prepared from 5-20 parts by weight of radix angelicae, 5-20 parts by weight of rose, 10-20 parts by weight of semen cuscutae, 5-20 parts by weight of concha haliotidis, 10-30 parts by weight of poria cocos, 20-40 parts by weight of semen coicis, 5-20 parts by weight of rhizoma typhonii, 5-20 parts by weight of bletilla striata, 10-20 parts by weight of radix ampelopsis, 10-30 parts by weight of radix puerariae, 10-20 parts by weight of edible tulip and 5-20 parts by weight of radix bupleuri.

4. The traditional Chinese medicine mask as claimed in claim 3, which is prepared from 10 parts by weight of radix angelicae, 10 parts by weight of rose, 15 parts by weight of semen cuscutae, 10 parts by weight of concha haliotidis, 20 parts by weight of poria cocos, 30 parts by weight of semen coicis, 10 parts by weight of rhizoma typhonii, 10 parts by weight of bletilla striata, 15 parts by weight of radix ampelopsis, 20 parts by weight of radix puerariae, 15 parts by weight of edible tulip and 10 parts by weight of radix bupleuri.

5. The traditional Chinese medicine mask as claimed in any one of claims 1 to 4, wherein the traditional Chinese medicine mask further comprises honey.

6. The method for preparing the traditional Chinese medicine mask as claimed in any one of claims 1 to 5, which comprises the following steps:

7. The preparation method of the traditional Chinese medicine mask as claimed in claim 6, wherein the ultrafine powder in the step (1) is sieved by a 400-mesh sieve.

8. The method for preparing the traditional Chinese medicine mask as claimed in claim 6, wherein honey is added in the step (2) in an amount of 1ml/5g of the powder.

9. Use of the traditional Chinese medicine mask as set forth in any one of claims 1 to 5 for preparing a cosmetic having whitening effect.

10. Use of the traditional Chinese medicine mask as set forth in any one of claims 1 to 5 in the preparation of cosmetics with acne-removing efficacy.