CN114732732B - System and process for preparing particles for treating cardiovascular and cerebrovascular diseases - Google Patents

System and process for preparing particles for treating cardiovascular and cerebrovascular diseases Download PDF

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Publication number
CN114732732B
CN114732732B CN202210546546.1A CN202210546546A CN114732732B CN 114732732 B CN114732732 B CN 114732732B CN 202210546546 A CN202210546546 A CN 202210546546A CN 114732732 B CN114732732 B CN 114732732B
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station
medicine
plate
boiling
primary
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CN114732732A (en
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张元坤
王志标
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Anhui Kangxin Pharmaceutical Co ltd
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Anhui Kangxin Pharmaceutical Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D11/00Solvent extraction
    • B01D11/02Solvent extraction of solids
    • B01D11/0215Solid material in other stationary receptacles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention relates to a preparation system of blood vessel particles for treating heart and brain, which is provided with a discharge plate, a transfer plate and a feed plate in sequence from left to right along the length direction of a frame, wherein a primary boiling station is arranged between the feed plate and the transfer plate, and a secondary boiling station is arranged between the transfer plate and the discharge plate; two groups of cleaning mechanisms with opposite directions are sequentially arranged between the frames from left to right, and the cleaning mechanisms are driven by the transmission unit to push medicinal materials on the feeding plate to the medicine storage mechanism of the primary boiling station in cooperation with the guide plate; according to the invention, the primary boiling station and the secondary boiling station are used for boiling simultaneously, so that the boiling time is reduced, and after boiling is finished, the liquid medicine boiled for the two times is timely mixed, so that the medicine property is prevented from being lost, the medicine effect is ensured, and the problems that the time is wasted when the liquid medicine boiled for the first time is mixed after the two times are boiled in sequence, and the medicine property is possibly lost along with time are solved.

Description

System and process for preparing particles for treating cardiovascular and cerebrovascular diseases
Technical Field
The invention relates to the technical field of medicine preparation, in particular to a preparation system and a preparation process of particles for treating cardiovascular and cerebrovascular diseases.
Background
Cardiovascular and cerebrovascular diseases are the first diseases causing death of human beings, and with the improvement of the social life level and the aging of population, the research of cardiovascular and cerebrovascular diseases has become a hot spot for drug development. Coronary atherosclerotic heart disease, abbreviated as coronary heart disease, is caused by the fact that some blood lipid substances such as cholesterol, triglyceride and the like which cannot permeate into the arterial wall are deposited on the inner membrane of an artery to form an 'atheromatous plaque', and then the original elastic artery is hardened due to the calcium deposition in the liquid, so that along with the increase of the atheromatous plaque on the inner membrane of the artery, the vascular cavity is narrowed and even blocked, and myocardial ischemia, hypoxia or necrosis are caused.
The patent document with the patent number of CN113694136B discloses a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and a preparation method thereof, wherein the traditional Chinese medicine comprises the following raw materials in parts by weight: 64-84 parts of astragalus membranaceus, 64-84 parts of radix salviae miltiorrhizae, 27-47 parts of codonopsis pilosula, 27-47 parts of dwarf lilyturf tuber, 49-69 parts of rhizoma alismatis, 27-47 parts of honey-fried licorice root, 27-47 parts of schisandra chinensis, 27-47 parts of prepared rehmannia root, 27-47 parts of Chinese angelica, 27-47 parts of safflower, 27-47 parts of cassia twig, 27-47 parts of red paeony root, 19-39 parts of szechuan lovage rhizome, 49-69 parts of hawthorn, 27-47 parts of poria cocos, 19-39 parts of coptis chinensis, 27-47 parts of immature bitter orange, 49-69 parts of dragon bone, 49-69 parts of oyster, 49-69 parts of cassia seed, 49-69 parts of gynostemma pentaphylla and 27-47 parts of plantain seed. The Chinese medicine can reduce blood viscosity in a short period, change the ischemic and anoxic state of myocardial tissue, and gradually recover heart function; hospitalization is avoided, and more than 80% of patients do not need a bracket or bypass.
However, in the actual use process, the inventor finds that when part of medicinal materials for treating cardiovascular and cerebrovascular diseases are boiled, the medicinal materials need to be boiled twice, and the medicinal liquids boiled twice are mixed, and the two boiled medicinal liquids are boiled sequentially and then mixed, so that the time is wasted, and the medicinal liquids boiled for the first time can possibly run off the medicinal properties with time.
Disclosure of Invention
The invention aims at overcoming the defects of the prior art, the medicine is stored through the medicine storage mechanism arranged in the medicine barrel, the medicine is boiled in the primary boiling station and the secondary boiling station at the same time, the boiling time is reduced, after boiling is finished, the two boiling medicines are timely mixed, and the medicine property loss is prevented, so that the medicine effect is ensured, the medicine on the medicine storage mechanism of the primary boiling station is pushed into the medicine storage mechanism of the secondary boiling station by the cooperation of the cleaning mechanism, the medicine on the secondary boiling station is pushed out to the waste box, the automatic medicine changing boiling function is achieved, the automaticity is high, and the problems that the medicine for treating cardiovascular and cerebrovascular diseases in the prior art needs to be boiled twice, the medicine for treating the cardiovascular and cerebrovascular diseases in the prior art is mixed, the time is wasted when the medicine for the two boiling is mixed, and the medicine for the primary boiling is likely to be lost in time are solved.
Aiming at the technical problems, the technical scheme is as follows: a preparation system for treating cardiovascular and cerebrovascular blood vessel particles, which is provided with a discharge plate, a transfer plate and a feed plate in sequence from left to right along the length direction of a frame, wherein a primary boiling station is arranged between the feed plate and the transfer plate, and a secondary boiling station is arranged between the transfer plate and the discharge plate;
the primary decoction station and the secondary decoction station are both provided with a medicine storage mechanism, the medicine storage mechanism moves right above the corresponding medicine barrel along the axis of the corresponding medicine barrel under the drive of the driving mechanism, and the medicine storage mechanism comprises a disc provided with a plurality of uniformly arranged filter holes, a connecting frame fixedly and symmetrically arranged above the disc, a gear unit fixedly connected with the connecting frame and a rack unit fixedly arranged on the frame and meshed with the gear unit;
the circular disc is provided with a groove, the joint of the circular disc and the groove is provided with a round angle, one side of the groove is provided with a blocking door through an elastic unit, and a first induction unit is arranged above the primary boiling station of the machine frame;
two sets of clearance mechanisms with opposite directions are arranged between the frames from left to right in sequence, the clearance mechanisms are matched with the guide plates under the driving of the transmission unit to push medicinal materials on the feeding plate to the medicine storage mechanism of the primary decoction station, the medicinal materials on the medicine storage mechanism of the primary decoction station are synchronously pushed to the medicine storage mechanism of the secondary decoction station through the middle rotating plate, and the clearance mechanisms comprise a first pushing component for clearing the medicine storage mechanism and a second pushing component for clearing the middle rotating plate and the discharging plate.
Preferably, the first pushing component comprises a first outer cavity a arranged on the transmission unit, a first outer cavity b arranged on the transmission unit and fixedly connected with the first outer cavity a, a first bamboo brush handle and a sliding rod which are respectively and slidably connected in the first outer cavity a and the first outer cavity b, and a first guide rod a and a first guide rod b which are respectively and fixedly connected on the first bamboo brush handle and the sliding rod and penetrate through the first outer cavity a and the first outer cavity b to the outside of the first outer cavity a;
the first outer cavity a and the first outer cavity b are respectively provided with a through groove matched with the first guide rod a and the first guide rod b.
Preferably, the second pushing component comprises a second outer cavity arranged on the transmission unit, a second bamboo brush handle which is connected in the second outer cavity in a sliding way, and a second guide rod which is fixedly connected with the second bamboo brush handle and penetrates through the second outer cavity to the outside of the second outer cavity;
the second outer cavity is provided with a through groove matched with the second guide rod;
the guide plates are symmetrically arranged at the bottom of the frame, and the guide plates are respectively provided with a first chute matched with the first guide rod a and the first guide rod b and a second chute matched with the second guide rod.
Preferably, the rack is rotationally connected with a rotary table which is overlapped with the axis of the medicine barrel on the primary boiling station, two groups of mixing barrels are symmetrically arranged along the circumferential direction of the rotary table, and the medicine barrel is connected with the rack through a supporting piece.
Preferably, the device also comprises a stirring mechanism arranged in the mixing barrel and used for stirring the liquid medicine in the mixing barrel, and a flushing mechanism arranged on the frame and used for cleaning the residual ointment in the mixing barrel below the stirring mechanism;
the stirring mechanism comprises a stirring shaft penetrating through the bottom of the mixing barrel, stirring blades arranged on the inner surface of the mixing barrel and positioned on the stirring shaft, and a rotating gear arranged on the bottom of the stirring shaft;
the bottom of the outer surface of the support piece positioned on the primary boiling station is provided with an outer gear ring which is matched with the rotating gear.
Preferably, a discharging pipe and a feeding pipe are respectively arranged on one side, close to the mixing barrel, of the medicine barrel, a discharging pipe is arranged at the bottom of the outer surface of the mixing barrel, control valves are arranged on the discharging pipe and the discharging pipe, and a magnetic connecting assembly is arranged between the discharging pipe and the feeding pipe;
the magnetic connecting assembly comprises a supporting plate connected with the discharging pipe, a hose arranged on the supporting plate and communicated with the discharging pipe, an electromagnetic plate connected with the supporting plate through a plurality of groups of elastic units and a magnetic plate arranged at one end of the feeding pipe.
Preferably, a storage bin is arranged above the frame, and a second induction unit is arranged between the first pushing component and the second pushing component, wherein the initial position of the first pushing component and the second pushing component is positioned above the secondary boiling station.
A preparation process of a preparation system of particles for treating cardiovascular and cerebrovascular diseases comprises the following steps:
step one, a medicinal material extracting procedure, namely, after medicinal materials are decocted, starting a driving mechanism, respectively lifting a medicine storage mechanism on a primary decoction station and a secondary decoction station upwards, discharging medicinal liquid through a filtering hole in the lifting process, namely, lifting the medicinal materials on the primary decoction station to the position below a feeding plate and the position above a middle rotating plate, lifting the medicinal materials on the secondary decoction station to the position below the middle rotating plate and the position above a discharging plate, and enabling a disc to deflect at a certain angle through a rack unit in the process of moving to the highest point;
step two, a medicinal material replacement procedure, when a medicine storage mechanism is lifted to the highest point, a first sensing unit detects and sends a signal to a control end, so that the control end commands a transmission unit to move for one circle, a cleaning mechanism on the transmission unit is transported, the latter group along the transmission direction of the cleaning mechanism can move to a primary boiling station, a medicinal material on the primary boiling station is pushed to a middle rotating plate by matching with a corresponding guide plate, the medicinal material on a feeding plate is pushed to a medicine storage mechanism on the primary boiling station, the other group of cleaning mechanism normally pushes the medicinal material on the secondary boiling station to a discharging plate by matching with the corresponding guide plate through the primary boiling station, and meanwhile, the medicinal material on the middle rotating plate is pushed to the medicine storage mechanism on the secondary boiling station, and then returns to an initial position to wait for the next operation;
and thirdly, a liquid medicine treatment procedure, when the medicine storage mechanism is lifted out by a certain height, a control valve on a medicine barrel discharging pipe is opened, liquid medicine in the medicine barrels on the primary boiling station and the secondary boiling station enters the interior of the mixing barrel through the discharging pipe and a feeding pipe communicated with the liquid medicine in the medicine barrel, after the liquid medicine enters the mixing barrel, the control valve is closed, a new water source is added into the medicine barrel, the mixing barrel is rotated 180 degrees to a heating station through a rotary table, the liquid medicine in the mixing barrel is stirred through a stirring mechanism in the transferring process, after the liquid medicine is transferred to the heating station, the other mixing barrel which is symmetrically arranged with the heating station just moves between the primary boiling station and the secondary boiling station and is communicated with the two medicine barrels again, at the moment, after the boiling is completed, the control valve of the liquid medicine discharging pipe of the mixing barrel on the heating station is opened, the liquid medicine in the mixing barrel is discharged, and the liquid medicine in the mixing barrel is rotated 180 degrees to return to the initial position, and the interior of the mixing barrel is cleaned through a flushing mechanism in the rotating process.
Preferably, the first group of plaster decocted in the first decoction station in the first step cannot enter the mixing barrel, can enter the temporary storage box through a separate conduit for collection, and enters the mixing barrel together with the plaster decocted in the last time in the second decoction station, so that the work in the third step is performed.
Preferably, in the first step, the medicinal materials include radix Puerariae, rhizoma Polygonati and Glycyrrhrizae radix.
The invention has the beneficial effects that:
(1) According to the invention, medicinal materials are stored through the medicine storage mechanism arranged in the medicine barrel, the medicinal materials of the same batch of materials are boiled in different groups on the primary boiling station and the secondary boiling station, the two groups are boiled simultaneously, so that the boiling time of the medicinal materials needing to be boiled twice is reduced, the medicinal materials needing to be boiled for the first time are required to be boiled for the second time when the medicinal materials are mixed, and after the boiling is finished, the medicinal materials needing to be boiled for the second time are timely mixed, the medicinal materials are prevented from losing, so that the medicinal materials are ensured, the medicinal materials on the medicine storage mechanism of the primary boiling station are pushed into the medicine storage mechanism of the secondary boiling station by the cooperation of the cleaning mechanism, each station is in a specific boiling environment, namely, different temperature conditions are required when the medicinal materials needing to be boiled for the first time and the second time, the medicinal materials needing to be boiled for the first time are only required to be transferred to the stations needing to be boiled for the second time, and on the other hand, the medicinal materials on the secondary boiling stations are simultaneously pushed out to the box, so that the automatic medicine changing and boiling functions are achieved;
(2) According to the invention, the mixed liquid medicine is stirred in time in the transferring process by arranging the stirring mechanism and the flushing mechanism, so that the liquid medicine for two times can be fully mixed, the liquid medicine is matched with temperature control in the mixing process to carry out final processing on the liquid medicine, the liquid medicine is timely output after processing, and the mixing barrel is flushed in time after the liquid medicine is discharged, so that the cleanliness of the next working process is improved, the influence of residual liquid medicine on the new mixed liquid medicine is prevented, the automatic circulation working effect is achieved, meanwhile, the whole switching time is not longer than the time of once boiling of the medicinal materials, multiple groups of working are synchronously carried out at the same time, the working efficiency is greatly improved, a worker can conveniently monitor the whole processing process of a group of liquid medicine in a real-time penetrating manner, and the plaster boiling quality is improved;
(3) According to the invention, the medicine barrel and the mixing barrel can be automatically connected through the magnetic connecting component, so that the situation that the medicine barrel and the mixing barrel are separated and transferred manually when transferring is avoided, the working efficiency is improved, and the automation strength of the whole equipment is improved.
In conclusion, the equipment has the advantages of high working efficiency, good quality and strong automation capacity, and is particularly suitable for the technical field of medicine preparation.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, it being obvious that the drawings described below are only some embodiments of the present invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of a system for preparing particles for treating cardiovascular and cerebrovascular diseases.
Fig. 2 is a schematic view showing a state in which the medicine storage mechanism is raised to the highest point.
Fig. 3 is a schematic structural view of the cleaning mechanism.
Fig. 4 is a schematic view of the movement state of the cleaning mechanism.
Fig. 5 is a partial enlarged view at a shown in fig. 2.
Fig. 6 is a schematic structural view of the front plate in the guide plate.
Fig. 7 is a schematic view of the structure of the rear plate in the guide plate.
Fig. 8 is a schematic structural view of the first pushing component.
Fig. 9 is a schematic structural view of a second pushing assembly.
Fig. 10 is a schematic structural diagram of a medicine barrel and a mixing barrel.
Fig. 11 is a schematic structural view of the magnetic connection assembly.
Fig. 12 is a schematic view of the movement state of the mixing tub.
Fig. 13 is a schematic structural view of the stirring mechanism.
FIG. 14 is a schematic diagram of the process flow of the present invention.
Fig. 15 is a schematic view of the structure of fig. 4 at another view angle.
Fig. 16 is a partial schematic view of the structure of fig. 15.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below with reference to the accompanying drawings.
Example 1
As shown in fig. 1-5 and fig. 15-16, a system for preparing particles for treating cardiovascular and cerebrovascular diseases is provided, wherein a discharging plate 200, a middle rotating plate 300 and a feeding plate 400 are sequentially installed along the length direction of a frame 100 from left to right, a primary boiling station is arranged between the feeding plate 400 and the middle rotating plate 300, and a secondary boiling station is arranged between the middle rotating plate 300 and the discharging plate 200;
the primary decoction station and the secondary decoction station are both provided with a medicine storage mechanism 1, the medicine storage mechanism 1 moves right above a corresponding medicine barrel 500 along the axis of the corresponding medicine barrel 500 under the drive of a driving mechanism 7, and the medicine storage mechanism 1 comprises a disc 11 provided with a plurality of evenly arranged filter holes, a connecting frame 12 fixedly and symmetrically arranged above the disc 11, a gear unit 13 fixedly connected with the connecting frame 12 and a rack unit 14 fixedly arranged on a frame 100 and meshed with the gear unit 13;
a groove 15 is formed in the disc 11, a connection part of the disc 11 and the groove 15 is provided with a round corner, one side of the groove 15 is provided with a baffle 16 through an elastic piece, and a first sensing unit 17 is arranged above the primary boiling station of the frame 100;
two groups of cleaning mechanisms 2 with opposite directions are sequentially arranged between the machine frames 100 from left to right, the cleaning mechanisms 2 are driven by the transmission unit 600 to be matched with the guide plates 3 to push medicinal materials on the feeding plate 400 to the medicine storage mechanism 1 of the primary decoction station, the medicinal materials on the medicine storage mechanism 1 of the primary decoction station are synchronously pushed to the medicine storage mechanism 1 of the secondary decoction station through the middle rotating plate 300, and the cleaning mechanisms 2 comprise a first pushing component 21 for cleaning the medicine storage mechanism 1 and a second pushing component 22 for cleaning the middle rotating plate 300 and the discharging plate 200.
Cardiovascular and cerebrovascular diseases are the general terms of cardiovascular and cerebrovascular diseases, and refer broadly to ischemic or hemorrhagic diseases of heart, brain and systemic tissues caused by hyperlipidemia, blood viscosity, atherosclerosis, hypertension, etc.
In this embodiment, when the medicinal material of partly treating cardiovascular and cerebrovascular diseases is in the boiling, need through twice boiling to mix the medicinal liquid of twice boiling, and deposit the medicinal material through setting up the medicine storage mechanism 1 in medicine barrel 500, decoct simultaneously on first time boiling station and second time boiling station, reduce the boiling time, and after the boiling finishes, timely mix the medicinal liquid of twice boiling, prevent the medicinal material loss, thereby guarantee the medicinal effect, and cooperate clearance mechanism 2 to push the medicinal material on the medicine storage mechanism 1 of first time boiling station to the medicine storage mechanism 1 on the second time boiling station, push out the medicinal material on the second time boiling station to the abandonment case, reach the function of automatic medicine changing and boiling, and automaticity is strong.
In detail, after the boiling is finished, the driving mechanism 7 is started to drive the disc 11 to lift upwards, and in the rising process, the gear unit 13 is matched with the rack unit 14, so that the gear unit 13 starts to rotate, that is, the disc 11 is deflected in angle through the connecting frame 12, when rising to the highest point, the first sensing unit 17 detects and sends a signal to the control end, so that the control end commands the transmission unit 600 to move for a circle, thereby transporting the cleaning mechanism 2 on the transmission unit 600, the latter group along the transmission direction moves to the primary boiling station, and cooperates with the corresponding guide plate 3 to open the baffle door 16 on the disc 11 on the primary boiling station, push the medicinal material in the groove 15 to the middle plate 300, and simultaneously push the medicinal material on the feeding plate 400 to the groove 15 on the primary boiling station, and the other group of cleaning mechanism 2 normally opens the baffle door 16 on the disc 11 on the secondary boiling station through the primary boiling station and cooperates with the corresponding guide plate 3, push the medicinal material in the groove 15 to the discharge plate 200, and simultaneously push the medicinal material on the disc 11 to the primary boiling station, and then the primary boiling station 1 is waited for a second time.
Further, as shown in fig. 1, 3, 6, 7 and 8, the first pushing assembly 21 includes a first outer cavity a211 installed on the transmission unit 600, a first outer cavity b212 installed on the transmission unit 600 and fixedly connected to the first outer cavity a211, a first bamboo brush handle 213 and a sliding rod 214 respectively slidably connected to the first outer cavity a211 and the first outer cavity b212, and a first guide rod a245 and a first guide rod b216 respectively fixedly connected to the first bamboo brush handle 213 and the sliding rod 214 and penetrating the first outer cavity a211 and the first outer cavity b212 to the outside thereof;
the first outer cavity a211 and the first outer cavity b212 are respectively provided with a through groove matched with the first guide rod a245 and the first guide rod b 216.
In this embodiment, the first outer cavity a211 and the first outer cavity b212 move along the conveying unit 600, when the first pushing component 21 moves to the position of the disc 11, the first guide rod a245 and the first guide rod b216 cooperate with the first chute 33, so that the first bamboo brush handle 213 and the slide bar 214 fall to be attached to the bottom surface of the groove 15 of the disc 11, and the slide bar 214 opens the shutter 16 on the disc 11 in the moving process, and then pushes the medicinal material in the groove 15 out through the first bamboo brush handle 213.
Further, as shown in fig. 1, 2 and 9, the second pushing assembly 22 includes a second outer cavity 221 installed on the conveying unit 600, a second bamboo brush handle 222 slidably connected to the inside of the second outer cavity 221, and a second guide rod 223 fixedly connected to the second bamboo brush handle 222 and penetrating the second outer cavity 221 to the outside thereof;
the second outer cavity 221 is provided with a through groove matched with the second guide rod 223;
the guide plate 3 includes a front plate 31 and a rear plate 32 symmetrically disposed at the bottom of the frame 100, and the front plate 31 and the rear plate 32 are respectively provided with a first chute 33 matched with the first guide rod a245 and the first guide rod b216 and a second chute 34 matched with the second guide rod 223.
In this embodiment, the second outer cavity 221 moves along the conveying unit 600, and when the second pushing component 22 moves to the discharging plate 200 and the transferring plate 300, the second guide rod 223 cooperates with the second chute 34 to make the second bamboo brush handle 222 descend to be respectively attached to the inner wall surfaces of the discharging plate 200 and the transferring plate 300, so as to push out the medicinal materials in the discharging plate 200 and the transferring plate 300.
Further, as shown in fig. 1, 2, 10, and 11 to 13, a turntable 700 is rotatably connected to the frame 100 and coincides with the axis of the medicine tank 500 at the primary decocting station, two sets of mixing tanks 800 are symmetrically arranged along the circumferential direction of the turntable 700, and the medicine tank 500 is connected to the frame 100 through a supporting member 900.
The device also comprises a stirring mechanism 4 which is arranged in the mixing barrel 800 and used for stirring the liquid medicine in the mixing barrel 800, and a flushing mechanism 5 which is arranged on the frame 100 and used for cleaning the residual ointment in the mixing barrel 800 below the stirring mechanism;
the stirring mechanism 4 comprises a stirring shaft 41 penetrating through the bottom of the mixing drum 800, stirring blades 42 arranged on the stirring shaft 41 and positioned on the inner surface of the mixing drum 800, and a rotating gear 43 arranged on the bottom of the stirring shaft 41;
an outer toothed ring 44 is mounted at the bottom of the outer surface of the support 900 at the primary boiling station, and the outer toothed ring 44 is matched with the rotating gear 43.
In this embodiment, the control valve on the discharging pipe 501 of the medicine barrel 500 is opened, the liquid medicine in the medicine barrel 500 on the primary boiling station and the liquid medicine in the medicine barrel 500 on the secondary boiling station enter the interior of the mixing barrel 800 through the discharging pipe 501 and the feeding pipe 801 communicated with the primary boiling station, after the liquid medicine enters the mixing barrel 800, the control valve is closed, a new water source is added into the medicine barrel 500, the mixing barrel 800 is rotated 180 degrees to the heating station through the rotary table 700, the liquid medicine in the mixing barrel 800 is stirred through the stirring mechanism 4 in the transferring process, after the liquid medicine is transferred to the heating station, the other mixing barrel 800 which is symmetrically arranged with the heating station just moves between the primary boiling station and the secondary boiling station and is communicated with the two medicine barrels 500 again, at the moment, after the boiling is completed, the liquid medicine in the mixing barrel 800 is discharged through the control valve on the heating station, and the liquid medicine in the mixing barrel 800 is rotated 180 degrees to the initial position, and the interior of the mixing barrel 800 is cleaned through the flushing mechanism 5 in the rotating process.
In detail, in the rotation process of the mixing tub 800, the rotation gear 43 is engaged with the external gear ring 44, so that the rotation gear 43 rotates, and the stirring blade 42 is driven to rotate by the stirring shaft 41, so as to stir the liquid medicine in the mixing tub 800 in the process.
Further, as shown in fig. 1, 2, 10, 11 and 12, a discharging pipe 501 and a feeding pipe 801 are respectively disposed on a side of the medicine barrel 500 close to the mixing barrel 800, a discharging pipe 802 is mounted at the bottom of the outer surface of the mixing barrel 800, control valves are mounted on the discharging pipe 501 and the discharging pipe 802, and a magnetic connecting assembly 6 is mounted between the discharging pipe 501 and the feeding pipe 801;
the magnetic connection assembly 6 comprises a support plate 61 connected with the discharge pipe 501, a hose 62 installed on the support plate 61 and communicated with the discharge pipe 501, an electromagnetic plate 63 connected with the support plate 61 through a plurality of groups of elastic units 64, and a magnetic plate 65 installed at one end of the feed pipe 801.
In this embodiment, when the mixing tub 800 rotates between the two medicine tubs 500, the electromagnetic plate 63 is energized to have magnetism so as to be attracted to the magnetic plate 65, thereby connecting the discharging pipe 501 and the feeding pipe 801 through the hose 62, and when the discharging pipe and the feeding pipe are separated from each other, the electromagnetic plate 63 is retracted through the elastic unit 64 so as to prevent the mixing tub 800 from being obstructed.
Further, as shown in fig. 1, 2, 3 and 12, a storage bin 81 is installed above the frame 100, and a second sensing unit is installed between the first pushing component 21 and the second pushing component 22, where the initial position is above the secondary decocting station.
In this embodiment, the medicine is stored by arranging the storage bin 81, and an electric control door is arranged below the storage bin 81, when the second induction unit passes through the storage bin 81, the electric control door can be opened to put the medicine stored in the storage bin 81 between the first pushing component 21 and the second pushing component 22, the initial positions of which are located above the secondary boiling station, namely, the medicine falls into the feeding plate 400 when the medicine rotates below the transmission unit 600, and then the medicine is pushed into the disc 11 on the primary boiling station through the second pushing component 22.
Example two
In this embodiment, the same or corresponding parts as those in the above embodiment are given the same reference numerals as those in the above embodiment, and only the points of distinction from the above embodiment will be described below for the sake of brevity. This embodiment differs from the above embodiment in that:
further, as shown in fig. 1-16, a preparation process of a preparation system of particles for treating cardiovascular and cerebrovascular diseases comprises the following steps:
step one, a medicinal material lifting procedure, namely, after medicinal materials are boiled, starting a driving mechanism 7, respectively lifting a medicinal material storage mechanism 1 on a primary boiling station and a secondary boiling station upwards, discharging medicinal liquid through a filtering hole in the lifting process, namely, lifting the medicinal materials on the primary boiling station to the position below a feeding plate 400 and the position above a transfer plate 300, lifting the medicinal materials on the secondary boiling station to the position below the transfer plate 300 and the position above a discharge plate 200, and enabling a disc 11 to deflect at a certain angle through a rack unit 14 in the process of moving to the highest point;
step two, in the medicine replacement procedure, when the medicine storage mechanism 1 is lifted to the highest point, the first sensing unit 17 detects and sends a signal to the control end, so that the control end commands the transmission unit 600 to move for one circle, the cleaning mechanism 2 on the transmission unit 600 is transported, the latter group along the transmission direction of the cleaning mechanism is moved to the primary decoction station, the medicine on the primary decoction station is pushed to the transfer plate 300 by matching with the corresponding guide plate 3, the medicine on the feeding plate 400 is pushed to the medicine storage mechanism 1 on the primary decoction station at the same time, the other group of cleaning mechanism 2 normally passes through the primary decoction station to the secondary decoction station, the medicine on the secondary decoction station is pushed to the discharge plate 200 by matching with the corresponding guide plate 3, and meanwhile, the medicine on the transfer plate 300 is pushed to the medicine storage mechanism 1 on the secondary decoction station, and then returns to the initial position to wait for the next work;
and thirdly, in the liquid medicine treatment process, when the medicine storage mechanism 1 is lifted out to a certain height, a control valve on a discharging pipe 501 of the medicine barrel 500 is opened, liquid medicine in the medicine barrel 500 on the primary boiling station and the liquid medicine in the medicine barrel 500 on the secondary boiling station are both fed into the mixing barrel 800 through the discharging pipe 501 and a feeding pipe 801 communicated with the liquid medicine on the primary boiling station, after the liquid medicine is fed into the mixing barrel 800, the control valve is closed, a new water source is added into the medicine barrel 500, the mixing barrel 800 is rotated 180 degrees to the heating station through a rotary table 700, the liquid medicine in the mixing barrel 800 is stirred through a stirring mechanism 4 in the transferring process, after the liquid medicine is transferred to the heating station, the other mixing barrel 800 which is symmetrically arranged with the heating station is just moved between the primary boiling station and the secondary boiling station and is communicated with the two medicine barrels 500 again, at the moment, after the heating station is finished, the control valve of the liquid medicine in the mixing barrel 800 on the heating station is opened to discharge the mixing barrel 800, the liquid medicine in the heating station is rotated 180 degrees, and the liquid medicine in the mixing barrel 800 is returned to the initial position 802, and the mixing barrel 800 is cleaned in the washing process through the rotating mechanism 5.
The first group of plaster decocted in the first decoction station in the first step cannot enter the mixing barrel 800, can enter the temporary storage box through a separate conduit for collection, and enters the mixing barrel 800 together with the plaster decocted in the last time in the second decoction station, so that the work in the third step is performed.
In the first step, the medicinal materials comprise radix puerariae, rhizoma polygonati and liquorice.
In this embodiment, the 2 nd decoction and the 1 st decoction are basically the same, but the time is different, the 2 nd general decoction is shorter, the decoction is put into the medicine barrel 500 on the primary decoction station according to a certain proportion among the radix puerariae, the rhizoma polygonati and the liquorice, the liquid medicine for the first decoction is transferred into the temporary storage box through the guide pipe, then the new medicinal material is put into the medicine barrel 500 on the primary decoction station through the first step and the second step, the medicinal material after the first decoction is transferred into the medicine barrel 500 on the secondary decoction station, so that the steps are repeated, the function of automatic production is achieved, and when the last group is reached, no new medicinal material is added, no liquid medicine is produced on the primary decoction station, the liquid medicine produced on the secondary decoction station and the liquid medicine for the first decoction stored in the temporary storage box are led into the mixing barrel 800, and the work in the third step is performed.
In addition, the existing twice decocting mode is that after the traditional Chinese medicine is decocted for the first time, the traditional Chinese medicine is decocted for 10-15 minutes with small fire after the decoction is boiled, after the time is up, the decocted liquid medicine is poured out, then the residue is left, some warm water is added, the residue left in the pot is soaked for 5 minutes, the decoction is decocted for 5 minutes with small fire after the soaking, then the liquid medicine is poured out, and the first liquid medicine and the second liquid medicine are mixed together;
in this embodiment, the medicine barrel 500 on the primary decoction station is firstly heated by small fire and then heated by big fire, the time ratio of the small fire to the big fire is 1:1.5, the decoction is carried out until the volume of the original juice is one third, the temperature is reduced, the mode of the secondary decoction station is consistent but the duration is reduced, the working time of the two groups of driving mechanisms 7 driving the medicine storage mechanism 1 to rise is consistent, but the lifting heights are different, and the medicine storage mechanism 1 on the primary decoction station is higher than the medicine storage mechanism 1 on the secondary decoction station.
In detail, kudzuvine root: raise yang and relieve muscle, promote eruption and stop diarrhea, relieve restlessness and stop warm. For treating typhoid fever, headache, dysphoria with smothery sensation, diabetes, diarrhea, dysentery, macula, hypertension, angina pectoris, deafness, and radix Puerariae flavone can increase cerebral and coronary blood flow. After the pueraria flavone is injected into the carotid artery of the anesthetized dog, the cerebral blood flow is increased, the vascular resistance is correspondingly reduced, and the effect is maintained for 2-20 minutes, for example, intravenous injection, the cerebral blood flow is slightly increased, the effect of epinephrine and norepinephrine on shrinking cerebral blood vessels cannot be relieved, but the cerebral circulation of patients with hypertension and arteriosclerosis can be improved, and the effect is mild. Pueraria flavone and Pueraria wine extract are injected into coronary artery and vein of dog to increase coronary blood flow and reduce vascular resistance. The method has the advantages that the rat abdominal cavity and the subcutaneous injection of the pueraria wine extract and the intraperitoneal injection of the pueraria decoction and the crystals proposed in the pueraria have the protection effect on heart ischemia reaction caused by posterior pituitrin, and the pueraria decoction has no obvious antihypertensive effect on hypertensive dogs after being orally taken;
rhizoma polygonati: tonify middle energizer and qi, moisten heart and lung, strengthen tendons and bones. The rhizoma polygonati has an inhibiting effect on acid bacteria in a test tube, and the decoction has obvious antibacterial effect on the administration of tubercle bacillus and the re-administration of lymphomegaly after infection of the guinea pigs with experimental tuberculosis, and can improve the health condition, and the curative effect is similar to that of isoniazid. Has only weak inhibition effect (the minimum antibacterial concentration is 500-1000 mg%) on typhoid bacillus, and has no inhibition effect (the minimum anti-seedling concentration) on staphylococcus aureus (1000 mg%);
licorice root: harmonizing middle energizer, relieving urgency, moistening lung, removing toxic substances, and harmonizing various drugs. Is used for treating weakness of spleen and stomach, anorexia, abdominal pain, loose stool, fatigue, fever, consumptive lung disease, cough, palpitation, and convulsion; can be used for treating sore throat, peptic ulcer, carbuncle, skin ulcer, toxic materials clearing away, food poisoning, and arrhythmia: the radix Glycyrrhizae Preparata extract (1 ml contains 1g of Chinese medicinal materials) is administered by intravenous injection at a ratio of 1g/kg after arrhythmia induced by aconitine for 2 min, and the control group is given with equal amount of physiological saline. The results show very significant differences for both ectopic and ventricular rhythms. Indicating that the honey-fried licorice root has obvious effect of resisting aconitine-induced arrhythmia. The prepared licorice decoction is infused into toad isolated from heart, so that the heart contraction amplitude can be obviously increased. Glycyrrhizin has exciting effect on isolated toad heart, and has obvious antagonism to acetylcholine, physostigmine, etc. and obvious synergistic effect to epinephrine.
In the description of the present invention, it should be understood that the directions or positional relationships indicated by the terms "front and rear", "left and right", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of description and simplification of the description, and do not indicate or imply that the apparatus or component in question must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as limiting the invention.
Of course, in this disclosure, those skilled in the art will understand that the term "a" or "an" is to be interpreted as "at least one" or "one or more," i.e., in one embodiment, the number of elements may be one, and in another embodiment, the number of elements may be multiple, and the term "a" is not to be construed as limiting the number.
The foregoing is merely a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions easily conceivable by those skilled in the art under the technical teaching of the present invention should be included in the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the protection scope of the claims.

Claims (5)

1. The preparation system for treating the cardiovascular and cerebrovascular blood vessel particles is characterized in that a discharging plate, a transfer plate and a feeding plate are sequentially arranged along the length direction of a frame from left to right, a primary decoction station is arranged between the feeding plate and the transfer plate, and a secondary decoction station is arranged between the transfer plate and the discharging plate;
the primary decoction station and the secondary decoction station are both provided with a medicine storage mechanism, the medicine storage mechanism corresponds to the position right above the medicine barrel and moves along the axis of the corresponding medicine barrel under the drive of the driving mechanism, and the medicine storage mechanism comprises a disc provided with a plurality of uniformly arranged filter holes, a connecting frame fixedly and symmetrically arranged above the disc, a gear unit fixedly connected with the connecting frame and a rack unit fixedly arranged on the frame and meshed with the gear unit;
the circular disc is provided with a groove, the joint of the circular disc and the groove is provided with a round corner, one side of the groove is provided with a baffle door through an elastic piece, and a first induction unit is arranged above the primary boiling station of the machine frame;
two groups of cleaning mechanisms with opposite directions are sequentially arranged between the frames from left to right, the cleaning mechanisms are driven by the transmission unit to match the guide plates to push medicinal materials on the feeding plate to the medicine storage mechanism of the primary decoction station, the medicinal materials on the medicine storage mechanism of the primary decoction station are synchronously pushed to the medicine storage mechanism of the secondary decoction station through the middle rotating plate, and the cleaning mechanisms comprise a first pushing component for cleaning the medicine storage mechanism and a second pushing component for cleaning the middle rotating plate and the discharging plate;
the first pushing assembly comprises a first outer cavity a arranged on the transmission unit, a first outer cavity b arranged on the transmission unit and fixedly connected with the first outer cavity a, a first bamboo brush handle and a sliding rod which are respectively and slidably connected in the first outer cavity a and the first outer cavity b, and a first guide rod a and a first guide rod b which are respectively and fixedly connected on the first bamboo brush handle and the sliding rod and penetrate through the first outer cavity a and the first outer cavity b to the outside of the first outer cavity a;
the first outer cavity a and the first outer cavity b are respectively provided with a through groove matched with the first guide rod a and the first guide rod b;
the second pushing assembly comprises a second outer cavity arranged on the transmission unit, a second bamboo brush handle which is connected inside the second outer cavity in a sliding manner, and a second guide rod which is fixedly connected with the second bamboo brush handle and penetrates through the second outer cavity to the outside of the second outer cavity;
the second outer cavity is provided with a through groove matched with the second guide rod;
the guide plate comprises a front plate and a rear plate which are symmetrically arranged at the bottom of the frame, and a first chute matched with the first guide rod a and the first guide rod b and a second chute matched with the second guide rod are respectively arranged on the front plate and the rear plate;
the machine frame is rotationally connected with a rotary table which is overlapped with the axis of the medicine barrel on the primary boiling station, two groups of mixing barrels are symmetrically arranged along the circumferential direction of the rotary table, and the medicine barrel is connected with the machine frame through a supporting piece;
the stirring mechanism is arranged in the mixing barrel and used for stirring the liquid medicine in the mixing barrel, and the flushing mechanism is arranged on the rack and used for cleaning the residual ointment in the mixing barrel below the stirring mechanism;
the stirring mechanism comprises a stirring shaft penetrating through the bottom of the mixing barrel, stirring blades arranged on the inner surface of the mixing barrel and positioned on the stirring shaft, and a rotating gear arranged on the bottom of the stirring shaft;
an outer gear ring is arranged at the bottom of the outer surface of the support piece positioned on the primary boiling station, and the outer gear ring is matched with the rotating gear;
a discharging pipe and a feeding pipe are respectively arranged on one side, close to the mixing barrel, of the medicine barrel, a discharging pipe is arranged at the bottom of the outer surface of the mixing barrel, control valves are arranged on the discharging pipe and the discharging pipe, and a magnetic connecting component is arranged between the discharging pipe and the feeding pipe;
the magnetic connecting assembly comprises a supporting plate connected with the discharging pipe, a hose arranged on the supporting plate and communicated with the discharging pipe, an electromagnetic plate connected with the supporting plate through a plurality of groups of elastic units and a magnetic plate arranged at one end of the feeding pipe.
2. The system for preparing particles for treating cardiovascular and cerebrovascular diseases according to claim 1, wherein the storage bin is arranged above the frame, and the second induction unit is arranged between the first pushing component and the second pushing component, the initial positions of which are above the secondary boiling station.
3. A preparation process of a preparation system of particles for treating cardiovascular and cerebrovascular diseases based on claim 2, which is characterized by comprising the following steps:
step one, a medicinal material extracting procedure, namely, after medicinal materials are decocted, starting a driving mechanism, respectively lifting a medicine storage mechanism on a primary decoction station and a secondary decoction station upwards, discharging medicinal liquid through a filtering hole in the lifting process, namely, lifting the medicinal materials on the primary decoction station to the position below a feeding plate and the position above a middle rotating plate, lifting the medicinal materials on the secondary decoction station to the position below the middle rotating plate and the position above a discharging plate, and enabling a disc to deflect at a certain angle through a rack unit in the process of moving to the highest point;
step two, a medicinal material replacement procedure, when a medicine storage mechanism is lifted to the highest point, a first sensing unit detects and sends a signal to a control end, so that the control end commands a transmission unit to move for one circle, a cleaning mechanism on the transmission unit is transported, the latter group along the transmission direction of the cleaning mechanism can move to a primary boiling station, a medicinal material on the primary boiling station is pushed to a middle rotating plate by matching with a corresponding guide plate, the medicinal material on a feeding plate is pushed to a medicine storage mechanism on the primary boiling station, the other group of cleaning mechanism normally pushes the medicinal material on the secondary boiling station to a discharging plate by matching with the corresponding guide plate through the primary boiling station, and meanwhile, the medicinal material on the middle rotating plate is pushed to the medicine storage mechanism on the secondary boiling station, and then returns to an initial position to wait for the next operation;
and thirdly, a liquid medicine treatment procedure, when the medicine storage mechanism is lifted out by a certain height, a control valve on a medicine barrel discharging pipe is opened, liquid medicine in the medicine barrels on the primary boiling station and the secondary boiling station enters the interior of the mixing barrel through the discharging pipe and a feeding pipe communicated with the liquid medicine in the medicine barrel, after the liquid medicine is completely filled, the control valve is closed, a new water source is added into the medicine barrel, the mixing barrel is rotated 180 degrees to a heating station through a rotary table, the liquid medicine in the mixing barrel is stirred through a stirring mechanism in the transferring process, after the liquid medicine is transferred to the heating station, the other mixing barrel which is symmetrically arranged with the heating station just moves between the primary boiling station and the secondary boiling station and is communicated with the two medicine barrels again, at the moment, after the boiling is completed, the upper control valve of the liquid medicine discharging pipe of the mixing barrel on the heating station is opened, the liquid medicine for mixed boiling is discharged, and then the liquid medicine is rotated 180 degrees to return to the initial position, and the interior of the mixing barrel is cleaned through a flushing mechanism in the rotating process.
4. The process of claim 3, wherein the first group of plaster decocted at the first decoction station in the first step is not introduced into the mixing tank, is introduced into the temporary storage tank through a separate conduit, and is introduced into the mixing tank together with the plaster decocted at the last time at the second decoction station, thereby performing the operation in the third step.
5. The process of claim 3, wherein in the first step, the medicinal materials include radix Puerariae, rhizoma Polygonati and Glycyrrhrizae radix.
CN202210546546.1A 2022-05-20 2022-05-20 System and process for preparing particles for treating cardiovascular and cerebrovascular diseases Active CN114732732B (en)

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