CN114668793A - Medicine for treating traumatic injury and preparation method, application method and application thereof - Google Patents

Medicine for treating traumatic injury and preparation method, application method and application thereof Download PDF

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CN114668793A
CN114668793A CN202210338269.5A CN202210338269A CN114668793A CN 114668793 A CN114668793 A CN 114668793A CN 202210338269 A CN202210338269 A CN 202210338269A CN 114668793 A CN114668793 A CN 114668793A
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traumatic injury
treating
treating traumatic
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向俊霖
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
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Abstract

The invention relates to the technical field of medicaments, in particular to a medicament for treating traumatic injury, a preparation method, a use method and application thereof, wherein the medicament comprises the following components in percentage by mol: 5-10% of litsea cubeba, 5-10% of clove, 5-20% of holly, 30-40% of menthol, 5-10% of camphor, 15-20% of sesame oil, 5-10% of peppermint oil, 5-10% of eucalyptus leaf and 5-10% of fennel, and all the medicinal materials used in the formula are safe and reliable, and all the medicinal materials are combined with each other, so that the traditional Chinese medicine composition has the characteristics of quick response, high cure rate, difficult recurrence, low cost, simple preparation and no side effect for treating traumatic injury, rheumatic arthritis, scapulohumeral periarthritis, numbness and psychroalgia and cervical vertebra swelling and pain.

Description

Medicine for treating traumatic injury and preparation method, application method and application thereof
Technical Field
The invention relates to the technical field of medicines, in particular to a medicine for treating traumatic injury and a preparation method, a using method and application thereof.
Background
Traumatic injury generally refers to soft tissue injury caused by falling, hitting, bumping, knocking and the like, mainly manifested by swelling and pain, and has a history of thousands of years in the treatment of traumatic injury in traditional Chinese medicine, and is called as traumatic injury in ancient times as a general theory of injuries, and is mostly caused by external force or over-force under the condition of incorrect posture. In traditional Chinese medicine, injuries of bones and muscles, swelling and pain due to blood stasis, disharmony between qi and blood, meridian obstruction and organ damage caused by external force acting on human body are collectively called traumatic injury.
At present, pseudo-ginseng for promoting blood circulation and removing blood stasis, radix zanthoxyli for detoxifying, promoting blood circulation, relieving pain and dispelling wind, scandent schefflera stem and leaf for relieving swelling and pain and the like are mostly adopted as the medicaments for treating the traumatic injury, but the existing medicaments have the defects of slow effect taking, high cost, certain side effect and the like.
Disclosure of Invention
The invention aims to provide a medicine for treating traumatic injury, a preparation method, a use method and application thereof, which at least can be used for realizing the technical effects of quick response, low cost and no side effect when treating the traumatic injury.
The invention is realized by the following technical scheme:
a medicine for treating traumatic injury comprises the following components in percentage by mol: 5-10% of litsea cubeba, 5-10% of clove, 5-20% of wintergreen, 30-40% of menthol, 5-10% of camphor, 15-20% of optimized oil, 5-10% of peppermint oil, 5-10% of eucalyptus leaf and 5-10% of fennel.
The medicines in the formula can be prepared into pharmaceutically acceptable external preparations, such as powder, paste, medicinal liquor and the like, by adopting a conventional preparation method.
Preferably, the preparation method of the medicine comprises the steps of mashing and mixing the formula according to the proportion, and soaking the mixture in pure sorghum liquor with the temperature of 40-70 ℃ for 1-3 months, wherein the mass ratio of the formula to the pure sorghum liquor is 1: 7 to 10, filtering and removing slag to obtain the finished product.
The application method comprises the steps of directly applying the medicine prepared by the invention to the affected part, wherein the dosage of the medicine is determined according to the area size of the affected part and the severity of the disease condition, dipping the medicine with absorbent cotton and lightly applying the medicine to the affected part three times a day for more than ten minutes each time for more than two days, and adding the medicine while lightly kneading the affected part, so that the curative effect is better.
The medicine prepared by the technical scheme has quick response, low cost, simple preparation and no side effect in treating traumatic injury.
In order to better implement the invention, the additive further comprises the following components in percentage by mole: 5-8% of litsea cubeba, 5-8% of clove, 5-8% of wintergreen, 35-40% of menthol, 5-8% of camphor, 16-18% of excellent oil, 5-8% of peppermint oil, 5-8% of eucalyptus leaf and 5-8% of fennel.
Through the technical scheme, the medicine prepared from the raw materials according to the scheme has more obvious and stable effect through multiple practical experiences.
The medicine for treating traumatic injury prepared by the scheme can also be used as a medicine for treating rheumatoid arthritis, and when the medicine is used for preparing the medicine for treating rheumatoid arthritis, the preparation method and the using method are the same, the medicine has quick response to the rheumatoid arthritis after being used,
high cure rate, difficult recurrence, low cost, simple preparation and no side effect.
The medicine prepared by the scheme can also be used as a medicine for treating scapulohumeral periarthritis, and when the medicine is used for preparing the medicine for treating scapulohumeral periarthritis, the preparation method and the use method are the same, and the medicine has the advantages of quick effect on the scapulohumeral periarthritis, high cure rate, difficult recurrence, low cost, simple preparation and no side effect.
The medicine for treating traumatic injury prepared by the scheme can also be used as a medicine for treating cold pain caused by numbness and swelling and pain of cervical vertebra, and has the advantages of obvious effect, quick response and no side effect after use.
Litsea cubeba, school name: dried mature fruit of litsea plant of cinnamomum genus of lauraceae family, nature and taste: warm in nature, pungent, slightly bitter, fragrant in flavor, nontoxic, entering liver, stomach and intestine channels, and has the following effects: expelling wind and cold, promoting blood circulation and regulating qi, killing parasites and removing toxic substances.
Clove, another name: baijie, qingke, lilac, seed clove, zhijiuxiang, male clove and cloves. It can warm the middle energizer, warm the kidney and descend the adverse flow of qi. Lowering the adverse flow of qi in the middle-warmer; the functions of warming kidney and tonifying yang are mainly indicated: it is indicated for hiccup, vomiting, regurgitation, dysentery, psychroalgia, bubo, hernia, and tinea.
Holly, also called frozen green, white wood skin, with veins like toothed fluorene, its leaf can stain red, leaf like toon, son red like bunge cherry, slightly acidic hot, nature and flavor: sweet, bitter, cool and nontoxic. The efficacy is as follows: soaking in wine, dispelling pathogenic wind, tonifying skin, invigorating liver and kidney, nourishing liver, strengthening tendons and bones.
Menthol, drug name: menthol has the function of mainly stimulating skin mucosa, has cool feeling on the part while relieving itching, diminishing inflammation and relieving pain, is clinically used for pain, inflammation and swelling, and can also be orally taken for treating headache, rhinitis, pharyngitis and laryngitis.
Camphor, another name: the main components of the camphor, the tidal brain, the naphtha and the tree brain are pure d-camphor which is a camphene compound and has the following properties: pungent, hot, non-toxic, efficacy: unblocking orifices, promoting qi stagnation, treating middle-jiao evil and evil qi, cholera and cardialgia, scabies, tinea, wind pruritus, dental caries, and killing parasites and repelling moth. In shoes.
High-quality oil, also known as turpentine, molecular formula: C10H16, is an essential oil, is extracted from Colophonium of Pinaceae by distillation or other method, and contains terpene as main ingredient, transparent colorless liquid with fragrance, and has effects of: promoting blood circulation, sterilizing, and resisting rheumatic arthritis, bacteria, influenza virus, and bronchitis.
The peppermint oil is colorless or light yellow clear liquid, has special cool fragrance, and has pungent taste and cool aftertaste. The color becomes dark gradually after long-term storage, and the efficacy is as follows: aromatic, flavoring and carminative agents, which are used to produce a cooling sensation on the skin or mucous membranes to alleviate discomfort, mainly pain, are preferred in the present invention to be a class a peppermint oil.
Eucalyptus leaves, namely eucalyptus leaves, eucalyptus globulus leaves, Chinese wildrye leaves and ash willows, and have the following properties: bitter and pungent, cool, efficacy: it can be used for treating common cold, influenza, dysentery, enteritis, arthralgia, cystitis, scald, scabies, erysipelas, neurodermatitis, eczema, carbuncle, sore, and toxic swelling.
Fennel, another name: shipping fennel, star anise, nature and taste: pungent, sweet and warm, efficacy: warming yang, dispelling cold, regulating qi-flowing, and treating middle-cold vomiting, cold hernia with abdominal pain, kidney deficiency with lumbago, dry and wet beriberi.
Use contraindications: the medicine is forbidden in menstrual period and pregnant woman, forbidden in skin ulceration and infection, forbidden in allergic skin, and forbidden for children under adult monitoring or doctor instruction.
The invention has the beneficial effects that:
the medicine prepared by the invention is a hereditary secret formula, is obtained by carrying out treatment practice of generations through continuous improvement, is safe and reliable for all medicinal materials used in the formula, is combined with each other, and has the characteristics of quick response, high cure rate, difficult recurrence, low cost, simple preparation and no side effect for treating traumatic injury, rheumatic arthritis, scapulohumeral periarthritis, numbness cold pain and cervical vertebra swelling and pain.
Detailed Description
The medicine for treating traumatic injury, rheumatoid arthritis, scapulohumeral periarthritis, numbness and psychroalgia and cervical vertebra swelling and pain of the invention is further explained by combining with specific examples, and all the raw medicinal materials used in the invention can be purchased in the medicinal material market.
Example 1
A medicine for treating traumatic injury comprises the following components in percentage by mol: 5% of litsea cubeba, 5% of clove, 10% of wintergreen, 40% of menthol, 5% of camphor, 20% of excellent oil, 5% of peppermint oil, 5% of eucalyptus leaf and 5% of fennel.
Example 2
A medicine for treating traumatic injury comprises the following components in percentage by mol: 7% of litsea cubeba, 7% of clove, 7% of wintergreen, 35% of menthol, 7% of camphor, 18% of excellent oil, 6% of peppermint oil, 7% of eucalyptus leaf and 6% of fennel.
Example 3
A medicine for treating traumatic injury comprises the following components in percentage by mol: 10% of litsea cubeba, 10% of clove, 5% of wintergreen, 30% of menthol, 10% of camphor, 15% of excellent oil, 10% of peppermint oil, 5% of eucalyptus leaf and 5% of fennel.
Example 4
The medicine for treating traumatic injury is characterized by comprising the following components in percentage by mol: 5% of litsea cubeba, 5% of clove, 20% of wintergreen, 30% of menthol, 5% of camphor, 15% of excellent oil, 5% of peppermint oil, 5% of eucalyptus leaf and 10% of fennel.
Example 5
The medicine for treating traumatic injury is characterized by comprising the following components in percentage by mol: 5% of litsea cubeba, 5% of clove, 5% of wintergreen, 35% of menthol, 10% of camphor, 15% of excellent oil, 5% of peppermint oil, 10% of eucalyptus leaf and 10% of fennel.
Example 6
The medicine for treating scapulohumeral periarthritis comprises the following components in percentage by mole: 7% of litsea cubeba, 7% of clove, 7% of wintergreen, 35% of menthol, 7% of camphor, 18% of excellent oil, 6% of peppermint oil, 7% of eucalyptus leaf and 6% of fennel.
Example 7
The medicine for treating the rheumatoid arthritis consists of the following components in percentage by mol: 7% of litsea cubeba, 7% of clove, 7% of wintergreen, 35% of menthol, 7% of camphor, 18% of excellent oil, 6% of peppermint oil, 7% of eucalyptus leaf and 6% of fennel.
The preparation method of the medicine is preferably that the formula is mashed and mixed according to the proportion, then the mixture is soaked in pure sorghum liquor with the temperature of 40-70 ℃ for 1-3 months, the mass ratio of the formula to the pure sorghum liquor is 1: 7-10, and the medicine is obtained by filtering and removing the residues.
The application method of the medicine is that the medicine prepared by the invention is directly applied to the affected part, the dosage of the medicine is determined according to the area size of the affected part and the severity of the illness state, the medicine cotton is dipped in the medicine and lightly applied to the affected part three times a day for more than ten minutes each time for more than two days, and the medicine is added while lightly kneading the affected part, so that the curative effect is better.
The effect of the present invention is illustrated below by several representative cases:
case 1
The medicine is applied to the affected part after being smeared on gauze, is changed and applied for three times every day, the pain is obviously relieved in the next day, the patient can normally walk, can fully recover after being continuously used for four days, can normally use the force for dry and active, and has no other diseases.
Case 2
When a patient is stretched, the waist is twisted and difficult to stand up when the patient plays basketball 12 month and 28 days 2021 year by 23 year old, the medicine is uniformly applied to the waist and is rubbed three times a day, the waist is not sore and painful after the patient uses the medicine for the next day, the patient can normally move, and the patient can continue playing basketball on the third day without other diseases.
Case 3
Patients who are critically ill, male, 68 years old, 8 months and 13 days in 2021 year fall down when going down stairs, waist injury and arm dislocation and gall are caused, after the medicine is applied for three times every day in the first two days and twice every day from the third day to the fifth day, the pain of the arms and the waist disappears, after the medicine is continuously applied for two days, normal activities are recovered, and the injured part does not feel pain any more and has no other diseases.
Case 4
The patient suffers from rheumatic arthralgia, right and left foot muscle soreness and discomfort, fatigue, irregular fever and hyperhidrosis for a long time in 5 months and 8 days in 2021 years in a certain age of male and 51 years old, and the medicine is coated for three times every day, and after two days, the pain of both feet disappears, the bone joints are not painful any more, the irregular fever does not appear any more, the whole person becomes energetic, and no other diseases are generated when the patient does not relapse.
Case 5
Patients have a certain Liu, female, age 57, 2021, 4 months and 4 days, shoulder joints are painful, do not move conveniently, and are afraid of cold when going to hospitals to diagnose as scapulohumeral periarthritis.
Case 6
The patient is zheng, woman, 41 years old, 2021 year 2 month 5 days, seven eight years of heel numbness, right thigh anterolateral numbness and cold pain, two hands and upper arm numbness, shoes, trousers and long-sleeve clothes with heel are worn at home all the year round, the whole body is wrapped up with thin clothes in summer, the left thigh is covered with thin quilt for a little long time after sitting, the medicine is smeared on the parts for three times every day, symptoms of numbness and pain disappear after three consecutive days, and the disease is completely cured, and no other diseases recur exist until now.
Case 7
The medicine is applied to an affected part three times a day, the cervical vertebra swelling and pain feel disappears after two days of application, the lumbar and ischiadic nerves are also improved, and the patient is healed after being continuously applied for three days, so far, no relapse or other diseases exist.
The results of the clinical cases show that the medicine of the invention can treat various diseases, has quick curative effect, difficult relapse, simple and convenient use and no side effect, and is especially suitable for traumatic injury, rheumatoid arthritis, scapulohumeral periarthritis, numbness and cold pain, and cervical vertebra swelling and pain.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (6)

1. The medicine for treating traumatic injury is characterized by comprising the following components in percentage by mol: 5-10% of litsea cubeba, 5-10% of clove, 5-20% of wintergreen, 30-40% of menthol, 5-10% of camphor, 15-20% of optimized oil, 5-10% of peppermint oil, 5-10% of eucalyptus leaf and 5-10% of fennel.
2. The medicine for treating traumatic injury according to claim 1, which is prepared from the following components in percentage by mole: 5-8% of litsea cubeba, 5-8% of clove, 5-8% of wintergreen, 35-40% of menthol, 5-8% of camphor, 16-18% of excellent oil, 5-8% of peppermint oil, 5-8% of eucalyptus leaf and 5-8% of fennel.
3. The preparation method of the medicine for treating traumatic injury according to claim 1 or 2, wherein the medicine is prepared by mashing and mixing the above formula according to the above proportion, soaking the mixture in pure kaoliang spirit with the temperature of 40-70 ℃ for 1-3 months, and filtering the mixture to remove residues, wherein the mass ratio of the formula to the pure kaoliang spirit is 1: 7-10.
4. The use method of a medicine for treating traumatic injury according to claim 1 or 2, characterized in that the prepared medicine is directly applied to the affected part and lightly applied to the affected part three times a day, ten minutes each time, and continuously for more than two days, and the medicine is added while lightly kneading the affected part to ensure the medicine permeation.
5. Use of the medicament for treating traumatic injury according to claim 1 or 2 in the preparation of a medicament for treating rheumatoid arthritis.
6. The use of the medicament for treating traumatic injury according to claim 1 or 2 in the preparation of a medicament for treating scapulohumeral periarthritis.
CN202210338269.5A 2022-04-01 2022-04-01 Medicine for treating traumatic injury and preparation method, application method and application thereof Pending CN114668793A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2093171C1 (en) * 1994-03-01 1997-10-20 Товарищество с ограниченной ответственностью предприятие "БИОМ" Medicinal agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2093171C1 (en) * 1994-03-01 1997-10-20 Товарищество с ограниченной ответственностью предприятие "БИОМ" Medicinal agent

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李艳秋,等: ""狮马龙"活络油抗炎作用的药效学研究", 《辽宁中医药大学学报》 *
梅全喜: "《广东地产药材研究》", 31 May 2011, 广东科技出版社 *

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