CN114642204B - 一种含昆虫生长调节剂类虫/螨剂的杀虫杀螨组合物 - Google Patents
一种含昆虫生长调节剂类虫/螨剂的杀虫杀螨组合物 Download PDFInfo
- Publication number
- CN114642204B CN114642204B CN202011492946.6A CN202011492946A CN114642204B CN 114642204 B CN114642204 B CN 114642204B CN 202011492946 A CN202011492946 A CN 202011492946A CN 114642204 B CN114642204 B CN 114642204B
- Authority
- CN
- China
- Prior art keywords
- active component
- insecticidal
- composition
- acaricidal
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 56
- 230000000895 acaricidal effect Effects 0.000 title claims abstract description 35
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 32
- 239000003795 chemical substances by application Substances 0.000 title claims abstract description 28
- 241000238631 Hexapoda Species 0.000 title claims abstract description 20
- 239000003630 growth substance Substances 0.000 title claims abstract description 10
- 150000001875 compounds Chemical class 0.000 claims abstract description 27
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 26
- 239000000642 acaricide Substances 0.000 claims abstract description 5
- 239000002917 insecticide Substances 0.000 claims abstract description 4
- 239000005937 Tebufenozide Chemical group 0.000 claims description 10
- QYPNKSZPJQQLRK-UHFFFAOYSA-N tebufenozide Chemical group C1=CC(CC)=CC=C1C(=O)NN(C(C)(C)C)C(=O)C1=CC(C)=CC(C)=C1 QYPNKSZPJQQLRK-UHFFFAOYSA-N 0.000 claims description 10
- 239000005900 Flonicamid Chemical group 0.000 claims description 9
- RLQJEEJISHYWON-UHFFFAOYSA-N flonicamid Chemical group FC(F)(F)C1=CC=NC=C1C(=O)NCC#N RLQJEEJISHYWON-UHFFFAOYSA-N 0.000 claims description 9
- RGNPBRKPHBKNKX-UHFFFAOYSA-N hexaflumuron Chemical group C1=C(Cl)C(OC(F)(F)C(F)F)=C(Cl)C=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F RGNPBRKPHBKNKX-UHFFFAOYSA-N 0.000 claims description 9
- 239000005912 Lufenuron Chemical group 0.000 claims description 8
- PWPJGUXAGUPAHP-UHFFFAOYSA-N lufenuron Chemical group C1=C(Cl)C(OC(F)(F)C(C(F)(F)F)F)=CC(Cl)=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F PWPJGUXAGUPAHP-UHFFFAOYSA-N 0.000 claims description 8
- 229960000521 lufenuron Drugs 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- 239000005942 Triflumuron Chemical group 0.000 claims description 6
- XAIPTRIXGHTTNT-UHFFFAOYSA-N triflumuron Chemical group C1=CC(OC(F)(F)F)=CC=C1NC(=O)NC(=O)C1=CC=CC=C1Cl XAIPTRIXGHTTNT-UHFFFAOYSA-N 0.000 claims description 6
- 239000004480 active ingredient Substances 0.000 claims description 5
- 230000001186 cumulative effect Effects 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims description 3
- 239000012752 auxiliary agent Substances 0.000 claims description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 10
- 241000344246 Tetranychus cinnabarinus Species 0.000 description 18
- 230000000694 effects Effects 0.000 description 16
- 238000012360 testing method Methods 0.000 description 14
- 230000001276 controlling effect Effects 0.000 description 10
- 239000003814 drug Substances 0.000 description 10
- 241000238876 Acari Species 0.000 description 9
- 239000007788 liquid Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 244000046052 Phaseolus vulgaris Species 0.000 description 5
- 230000001018 virulence Effects 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 238000005507 spraying Methods 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 238000005286 illumination Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 240000007124 Brassica oleracea Species 0.000 description 2
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 2
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 2
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 2
- 239000005944 Chlorpyrifos Chemical group 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- 241000255925 Diptera Species 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- 241000256602 Isoptera Species 0.000 description 2
- 239000005917 Methoxyfenozide Substances 0.000 description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 2
- -1 biphenyl compound Chemical class 0.000 description 2
- UISUNVFOGSJSKD-UHFFFAOYSA-N chlorfluazuron Chemical group FC1=CC=CC(F)=C1C(=O)NC(=O)NC(C=C1Cl)=CC(Cl)=C1OC1=NC=C(C(F)(F)F)C=C1Cl UISUNVFOGSJSKD-UHFFFAOYSA-N 0.000 description 2
- SBPBAQFWLVIOKP-UHFFFAOYSA-N chlorpyrifos Chemical group CCOP(=S)(OCC)OC1=NC(Cl)=C(Cl)C=C1Cl SBPBAQFWLVIOKP-UHFFFAOYSA-N 0.000 description 2
- 235000020971 citrus fruits Nutrition 0.000 description 2
- 229940125904 compound 1 Drugs 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000003912 environmental pollution Methods 0.000 description 2
- RYLHNOVXKPXDIP-UHFFFAOYSA-N flufenoxuron Chemical group C=1C=C(NC(=O)NC(=O)C=2C(=CC=CC=2F)F)C(F)=CC=1OC1=CC=C(C(F)(F)F)C=C1Cl RYLHNOVXKPXDIP-UHFFFAOYSA-N 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- QCAWEPFNJXQPAN-UHFFFAOYSA-N methoxyfenozide Chemical compound COC1=CC=CC(C(=O)NN(C(=O)C=2C=C(C)C=C(C)C=2)C(C)(C)C)=C1C QCAWEPFNJXQPAN-UHFFFAOYSA-N 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- CFRPSFYHXJZSBI-DHZHZOJOSA-N (E)-nitenpyram Chemical compound [O-][N+](=O)/C=C(\NC)N(CC)CC1=CC=C(Cl)N=C1 CFRPSFYHXJZSBI-DHZHZOJOSA-N 0.000 description 1
- NFGXHKASABOEEW-UHFFFAOYSA-N 1-methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate Chemical compound COC(C)(C)CCCC(C)CC=CC(C)=CC(=O)OC(C)C NFGXHKASABOEEW-UHFFFAOYSA-N 0.000 description 1
- 241000902876 Alticini Species 0.000 description 1
- 241001124076 Aphididae Species 0.000 description 1
- 241001048568 Apolygus lucorum Species 0.000 description 1
- 239000005874 Bifenthrin Chemical group 0.000 description 1
- 241001674044 Blattodea Species 0.000 description 1
- 235000011299 Brassica oleracea var botrytis Nutrition 0.000 description 1
- 240000003259 Brassica oleracea var. botrytis Species 0.000 description 1
- 239000005885 Buprofezin Substances 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 241000426497 Chilo suppressalis Species 0.000 description 1
- 239000005886 Chlorantraniliprole Substances 0.000 description 1
- 241001414720 Cicadellidae Species 0.000 description 1
- 241000008892 Cnaphalocrocis patnalis Species 0.000 description 1
- 241000254173 Coleoptera Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000289763 Dasygaster padockina Species 0.000 description 1
- 241001517923 Douglasiidae Species 0.000 description 1
- 239000005898 Fenoxycarb Substances 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- 241000255967 Helicoverpa zea Species 0.000 description 1
- 241000258937 Hemiptera Species 0.000 description 1
- 241000257303 Hymenoptera Species 0.000 description 1
- 241001531327 Hyphantria cunea Species 0.000 description 1
- 241000254022 Locusta migratoria Species 0.000 description 1
- 241000659518 Lozotaenia capensana Species 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 241000721696 Lymantria Species 0.000 description 1
- 244000141359 Malus pumila Species 0.000 description 1
- 241001477931 Mythimna unipuncta Species 0.000 description 1
- 244000183278 Nephelium litchi Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 241000346285 Ostrinia furnacalis Species 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 241000219998 Philenoptera violacea Species 0.000 description 1
- 241000255969 Pieris brassicae Species 0.000 description 1
- 241000758706 Piperaceae Species 0.000 description 1
- 241000500437 Plutella xylostella Species 0.000 description 1
- 239000005927 Pyriproxyfen Substances 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 241000256247 Spodoptera exigua Species 0.000 description 1
- 241001454293 Tetranychus urticae Species 0.000 description 1
- 241001414989 Thysanoptera Species 0.000 description 1
- 241000255993 Trichoplusia ni Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000000410 anti-febrile effect Effects 0.000 description 1
- 235000021016 apples Nutrition 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- OMFRMAHOUUJSGP-IRHGGOMRSA-N bifenthrin Chemical group C1=CC=C(C=2C=CC=CC=2)C(C)=C1COC(=O)[C@@H]1[C@H](\C=C(/Cl)C(F)(F)F)C1(C)C OMFRMAHOUUJSGP-IRHGGOMRSA-N 0.000 description 1
- 239000003139 biocide Substances 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 235000010290 biphenyl Nutrition 0.000 description 1
- 239000004305 biphenyl Substances 0.000 description 1
- PRLVTUNWOQKEAI-VKAVYKQESA-N buprofezin Chemical compound O=C1N(C(C)C)\C(=N\C(C)(C)C)SCN1C1=CC=CC=C1 PRLVTUNWOQKEAI-VKAVYKQESA-N 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- NDHXMRFNYMNBKO-PWSUYJOCSA-N chembl2227757 Chemical compound [O-][N+](=O)C([C@H]1CC[C@H](O1)N1CC2)=C1N2CC1=CC=C(Cl)N=C1 NDHXMRFNYMNBKO-PWSUYJOCSA-N 0.000 description 1
- PSOVNZZNOMJUBI-UHFFFAOYSA-N chlorantraniliprole Chemical compound CNC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl PSOVNZZNOMJUBI-UHFFFAOYSA-N 0.000 description 1
- CWFOCCVIPCEQCK-UHFFFAOYSA-N chlorfenapyr Chemical class BrC1=C(C(F)(F)F)N(COCC)C(C=2C=CC(Cl)=CC=2)=C1C#N CWFOCCVIPCEQCK-UHFFFAOYSA-N 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- HJUFTIJOISQSKQ-UHFFFAOYSA-N fenoxycarb Chemical compound C1=CC(OCCNC(=O)OCC)=CC=C1OC1=CC=CC=C1 HJUFTIJOISQSKQ-UHFFFAOYSA-N 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- FYQGBXGJFWXIPP-UHFFFAOYSA-N hydroprene Chemical compound CCOC(=O)C=C(C)C=CCC(C)CCCC(C)C FYQGBXGJFWXIPP-UHFFFAOYSA-N 0.000 description 1
- 229930000073 hydroprene Natural products 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 229930014550 juvenile hormone Chemical class 0.000 description 1
- 239000002949 juvenile hormone Chemical class 0.000 description 1
- 150000003633 juvenile hormone derivatives Chemical class 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229930002897 methoprene Natural products 0.000 description 1
- 229950003442 methoprene Drugs 0.000 description 1
- 229940079888 nitenpyram Drugs 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- NHDHVHZZCFYRSB-UHFFFAOYSA-N pyriproxyfen Chemical compound C=1C=CC=NC=1OC(C)COC(C=C1)=CC=C1OC1=CC=CC=C1 NHDHVHZZCFYRSB-UHFFFAOYSA-N 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- ZSDSQXJSNMTJDA-UHFFFAOYSA-N trifluralin Chemical compound CCCN(CCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O ZSDSQXJSNMTJDA-UHFFFAOYSA-N 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/14—Ethers
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/28—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof containing the group; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
本发明属于杀虫杀螨剂领域，涉及一种含昆虫生长调节剂类杀虫/螨剂的杀虫杀螨组合物。组合物含有活性组分A和活性组分B，活性组分A和活性组分B之间的重量份数比为1:99～99:1；活性组分A选自化合物Ⅰ，活性组分B选自昆虫生长调节剂类杀虫/螨剂；所述活性组分A结构如下，本发明的组合物具有增效明显、延缓抗性等优点，可用于防治多种害虫。
Description
技术领域
本发明属于杀虫杀螨剂领域，涉及一种含昆虫生长调节剂类虫/螨剂的杀虫杀螨组合物。
背景技术
杀虫杀螨剂在防治农林害虫或城市卫生害虫方面具有明显的作用。
中国发明专利CN105541682公开了一种联苯类化合物及其控制虫害和螨害的用途，其中化合物1(以下简称化合物Ⅰ)可用于防治多种害虫、害螨，尤其对害螨具有突出的防治效果。
含有单一活性组分的杀虫杀螨剂，在害虫防治上连续使用，容易使害虫产生抗药性。通过两种活性组分的杀虫杀螨剂按一定比例混配成混合组分，往往可以提高防效，减少有效成分的用量，节约成本，同时可以延缓害虫抗药性的产生。
尽管现有技术中泛泛公开记载了含化合物Ⅰ的杀虫杀螨剂组合物，但记载选用的另一组分间各不相同，进而获得的组合物在扩大杀虫谱上与其他组合物的侧重有所不同，并不能达到广谱性，同时其效果也不能相应的预期得到。
发明内容
本发明目的在于为了满足农林和城市卫生领域防治害虫方面对杀虫杀螨剂效果日渐提高和品种不断更新的需求，提供一种杀虫杀螨组合物。
为实现上述目的，本发明采用的技术方案为：
一种含昆虫生长调节剂类杀虫/螨剂的杀虫杀螨组合物，组合物为活性组分A和活性组分B，其中，活性组分A和活性组分B之间的重量份数比为1:99～99:1；活性组分A选自化合物Ⅰ，活性组分B选自昆虫生长调节剂类杀虫/螨剂；所述活性组分A化合物Ⅰ结构如下：
所述活性组分B选自氟铃脲、虱螨脲、除虫脲、氟环脲、双氟虫脲、氟啶脲、氟虫脲、氟酰脲、多氟脲、氟苯脲、杀铃脲、双三氟虫脲、氟幼脲、灭幼脲、啶蜱脲、虫酰肼、环虫酰肼、甲氧虫酰肼、氯虫酰肼、呋喃虫酰肼、抑食肼、氟啶虫酰胺、氯虫酰胺、环虫酰胺、甲氧虫酰胺、噻嗪酮、烯虫炔酯、烯虫酯、烯虫乙酯、三氟甲吡醚、吡丙醚、啶虫丙醚、苯氧威、灭蝇胺、灭虫隆或保幼激素类似物。
所述活性组分A为化合物Ⅰ，活性组分B选氟铃脲、虱螨脲、虫酰肼、氟啶虫酰胺或三氟甲吡醚；两种活性组分的重量份数比为50:1-1:50。
所述活性组分A为化合物Ⅰ，活性组分B选甲氟铃脲、虱螨脲、虫酰肼、氟啶虫酰胺或三氟甲吡醚；两种活性组分重量份数比为25:1-1:25。
所述活性组分A为化合物Ⅰ，活性组分B选氟铃脲、虱螨脲或虫酰肼；两种活性组分重量份数比为10:1-1:10。
所述活性组分A为化合物Ⅰ，活性组分B选氟啶虫酰胺或三氟甲吡醚；两种活性组分重量份数比为15:1-1:15。
一种含昆虫生长调节剂类杀虫/螨剂的杀虫杀螨组合物的应用，所述组合物在用于制备控制农业害虫或城市卫生害虫的杀虫杀螨剂中的应用。
以有效剂量计，将所述组合物施于需要控制的害虫或其生长的介质上。
本发明的组合物具体适合于防治多种重要的农业害虫如本发明还包括本发明组合物制备成杀虫杀螨制剂控制农林害虫或城市卫生害虫的用途。具体适合于防治多种重要的农业害虫如粘虫、甜菜夜蛾、棉铃虫、地老虎、甘蓝夜蛾、苹果卷叶蛾、稻纵卷叶螟、玉米螟、二化螟、小菜蛾、菜青虫、美国白蛾、天幕毛虫、舞毒蛾、东亚飞蝗、地下害虫、潜叶蛾、斑潜蝇、蚜虫、叶蝉、花卉介壳虫、马铃薯甲虫、跳甲、蓟马、盲蝽、朱砂叶螨、山楂叶螨、柑橘全爪螨、柑橘锈螨、苹果叶螨、二斑叶螨、瘿螨、粉螨等，城市害虫如白蚁、蜚蠊、蚂蚁、蝇类、蚊类等。用于果树如苹果、梨、柑桔、荔枝等，禾谷类如小麦、水稻等，豆类如大豆、菜豆等，棉花，蔬菜如甘蓝、花椰菜、白菜、油菜、番茄、辣椒以及花卉。用于防治城市害虫时，可以用于家庭、各种公共场所、办公场所，以及发生白蚁危害的树木、堤坝等。
进一步的说，一种含昆虫生长调节剂类杀虫/杀螨剂的杀虫杀螨组合物的使用方法，以有效剂量计，将制备的杀虫杀螨剂施于需要控制的害虫或其生长的介质上。通常选择的较为适宜有效剂量为每公顷10克到500克，优选有效剂量为每公顷15克到100克。
本发明的组合物可以所述组合物为活性成分与载体和任意一种助剂混合，制成制剂。
所述制剂中组合物的活性组分累积含量在0.5wt％-95wt％之间。优选，所述制剂中活性组分的累积含量在1％-85％之间。
本发明具有如下优点：
1.本发明的组合物在一定配比范围内对于杀虫杀螨表现出明显的增效作用，提高了组合物中各单一活性成分化合物对害虫的防治效果，两者互不相同作用形式的组合物按一定配比组合，实现协同效应。
2.本发明组合物在应用于杀虫杀螨中的使用剂量明显低于组合物中单一化合物的使用剂量，从而降低使用成本，减少环境污染。
3.本发明组合物中各有效成分在作用于杀虫和杀螨中的作用机理不同，不存在交互抗性的问题，用其防治害虫可以延缓害虫抗药性的发生，并且提高对抗性种群的防治效果。
4.本发明组合物相对于各单剂完善了广谱性，但增效效果并不是与单剂线性相关。
具体实施方式
以下具体实施例用于进一步详细说明本发明，但本发明绝非仅限于这些例子。实施例中各组分配比均以重量计。
下述活性组分A为中国发明专利CN105541682中记载的化合物1，其制备详见说明书中记载。
室内生物活性测定
实施例1含有化合物Ⅰ的组合物对朱砂叶螨的协同作用测定
供试对象：朱砂叶螨(Tetranychus cinnabarinus Boisduval)，成螨，室内饲养的敏感品系。
测试条件：温度：24～26℃，相对湿度：60％，光照：L:D＝14:10
药液配制：根据不同试验需要，用电子分析天平分别准确称取供试样品(本发明不同配比组合物和原药)，其中，原药以丙酮溶解，再用0.1％吐温80水按照试验设计剂量稀释成具一定浓度的药液。
试验方法：采用盆栽幼苗喷雾法测定对朱砂叶螨成螨的活性大小。首先将40-60头大小一致的朱砂叶螨成螨接到处于第一对真叶平展期的菜豆幼苗(留一片真叶)上，待成螨稳定后计数基数；然后采用Airbrush法用药液处理试材，每株1.5mL，设空白对照。
自然阴干后，将处理后的试材置于观察室内，观察室温度、湿度、光照按需可调节，72h后调查活螨数，计算死亡率。评价采用Bliss法，该方法是评价混剂作用的经典方法之一。Bliss根据其提出的独立联合作用概念认为，杀虫杀螨剂混用时的理论死亡率P可用下式来计算：
P＝Pm+Pn(1-Pm)
Pm为第一活性组分在浓度为m时靶标的死亡率(％)；Pn为第二活性组分使用浓度为n时靶标的死亡率(％)。
如果两种活性组分在以一定浓度混合后靶标的实际死亡率大于理论死亡率P，则判定两种活性组分在设定浓度下混合使用具有增效作用，反之则为拮抗作用。
结果见表1。
表1化合物Ⅰ与氟铃脲等3个药剂混合使用对朱砂叶螨成螨的协同作用测定
表2化合物Ⅰ与氟啶虫酰胺和三氟甲吡醚混合使用对朱砂叶螨成螨的协同作用测定
实施例2含有化合物Ⅰ的组合物对朱砂叶螨的室内活性测定
由上述协同作用测定效果数据可见本发明化合物Ⅰ与氟铃脲等5个药剂混合的组合物对朱砂叶螨成螨具有明显的增效效果，进一步以化合物Ⅰ和虫酰肼以供试5:1-1:5组成的组合物再用孙云沛(Sun y-p)法进行室内活性测定。
供试靶标：朱砂叶螨(Tetranychus cinnabarinus Boisduval)成螨，室内饲养的敏感品系。
药液配制：根据不同试验需要，用电子分析天平分别准确称取供试样品，其中，原药以丙酮溶解，再用0.1％吐温80水按照试验设计剂量稀释成具一定浓度梯度的系列药液。
试验方法：采用盆栽幼苗喷雾法测定对朱砂叶螨成螨的活性大小。首先将大小一致的朱砂叶螨成螨接到处于第一对真叶平展期的菜豆幼苗(留一片真叶)上，待成螨稳定后计数基数；然后将药液采用Airbrush喷雾法按试验设计从低剂量到高剂量的顺序均匀喷雾，每株1.5mL，每处理4次重复，另设空白对照。
将处理后的试材置于观察室内，观察室的温度、湿度、光照按需可调节。72小时后调查死、活螨数。用abbott公式计算校正死亡率，用DPS数据处理软件进行统计分析，求出各供试单剂及各不同配比混用的毒力回归方程式、LC50值及95％置信限，再用孙云沛(Sun y-p)法计算各配比的共毒系数，评价混用效果。
混剂的共毒系数(CTC值)按下列公式计算：
式中：ATI-混剂实测毒力指数；S-标准药剂的LC50值；M-混剂的LC50值。
TTI＝TIA×PA+TIB×PB
式中：TTI-混剂理论毒力指数；TIA-A药剂毒力指数；PA-A药剂在混剂中的百分含量；TIB-B药剂毒力指数；PB-B药剂在混剂中的百分含量。
式中：CTC-共毒系数；ATI-混剂实测毒力指数；TTI-混剂理论毒力指数。
复配剂的共毒系数(CTC)：CTC≥120表现为增效作用；CTC≤80表现为拮抗作用；80<CTC<120表现为相加作用。
且，组合物的LC50值小于其中一个或两个单剂的LC50值，则意味着在达到相同效果(死亡率为50％)时，组合物的使用剂量小于其中一个或两个单剂的使用剂量。
以试验结果见表2。
表2：化合物Ⅰ·虫酰肼对朱砂叶螨室内联合毒力测定结果
由上述数据可见化合物Ⅰ·虫酰肼配比1对朱砂叶螨LC50值为0.47mg/L，单剂LC50值分别为0.51mg/L和2.96mg/L，则意味着在达到相同效果(死亡率为50％)时，组合物的使用剂量(0.43mg/L)小于其中一个或两个单剂的使用剂量(0.51mg/L和2.96mg/L)；另，从共毒系数的定义看，组合物的防治效果也不同程度的高于两种单剂的理论效果；由于田间使用剂量和室内LC50值正相关，因此组合物田间使用剂量会相应降低，从而降低使用成本，减少环境污染。
Claims (9)
1.一种含昆虫生长调节剂类杀虫/螨剂的杀虫杀螨组合物，其特征在于：组合物为活性组分A和活性组分B，其中，活性组分A和活性组分B之间的重量份数比为1:99~99:1；活性组分A选自化合物Ⅰ，活性组分B选自氟铃脲、虱螨脲、虫酰肼、氟啶虫酰胺或三氟甲吡醚；所述活性组分A化合物Ⅰ结构如下：
化合物Ⅰ。
2.按照权利要求1所述的组合物，其特征在于：所述活性组分A为化合物Ⅰ，活性组分B选自氟铃脲、虱螨脲、虫酰肼、氟啶虫酰胺或三氟甲吡醚；两种活性组分的重量份数比为50:1-1:50。
3.按照权利要求2所述的组合物，其特征在于：所述活性组分A为化合物Ⅰ，活性组分B选自氟铃脲、虱螨脲、虫酰肼、氟啶虫酰胺或三氟甲吡醚；两种活性组分的重量份数比为25:1-1:25。
4.按照权利要求3所述的组合物，其特征在于：所述活性组分A为化合物Ⅰ，活性组分B选自氟铃脲、虱螨脲或虫酰肼；两种活性组分重量份数比为10:1-1:10。
5.按照权利要求3所述的组合物，其特征在于：所述活性组分A为化合物Ⅰ，活性组分B选自氟啶虫酰胺或三氟甲吡醚；两种活性组分重量份数比为15:1-1:15。
6.一种按照权利要求1所述的含昆虫生长调节剂类杀虫/螨剂的杀虫杀螨组合物的应用，其特征在于：所述组合物在用于制备控制农业害虫或城市卫生害虫的杀虫杀螨剂中的应用。
7.按照权利要求6所述的含昆虫生长调节剂类杀虫/螨剂的杀虫杀螨组合物的应用，其特征在于：以有效剂量计，将所述组合物施于需要控制的害虫或其生长的介质上。
8.一种杀虫杀螨制剂，其特征在于：以权利要求1所述组合物为活性成分与载体和任意一种助剂混合，制成制剂。
9.按照权利要求8所述的杀虫杀螨制剂，其特征在于：所述制剂中组合物的活性组分累积含量在0.5 wt %-95wt%之间。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011492946.6A CN114642204B (zh) | 2020-12-17 | 2020-12-17 | 一种含昆虫生长调节剂类虫/螨剂的杀虫杀螨组合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011492946.6A CN114642204B (zh) | 2020-12-17 | 2020-12-17 | 一种含昆虫生长调节剂类虫/螨剂的杀虫杀螨组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114642204A CN114642204A (zh) | 2022-06-21 |
| CN114642204B true CN114642204B (zh) | 2023-06-13 |
Family
ID=81989972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011492946.6A Active CN114642204B (zh) | 2020-12-17 | 2020-12-17 | 一种含昆虫生长调节剂类虫/螨剂的杀虫杀螨组合物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114642204B (zh) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013060420A (ja) * | 2011-08-23 | 2013-04-04 | Ishihara Sangyo Kaisha Ltd | 有害生物防除剤 |
| CN110037021A (zh) * | 2019-05-22 | 2019-07-23 | 侨昌现代农业有限公司 | 一种含联苯类增效型杀螨剂的杀螨组合物 |
| CN110367255A (zh) * | 2019-06-27 | 2019-10-25 | 山东康乔生物科技有限公司 | 包含螺甲螨酯和三氟乙基硫化物类杀虫剂的协同杀虫组合物及其应用 |
| CN111226945A (zh) * | 2018-11-29 | 2020-06-05 | 沈阳中化农药化工研发有限公司 | 一种协同杀虫杀螨组合物 |
-
2020
- 2020-12-17 CN CN202011492946.6A patent/CN114642204B/zh active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013060420A (ja) * | 2011-08-23 | 2013-04-04 | Ishihara Sangyo Kaisha Ltd | 有害生物防除剤 |
| CN111226945A (zh) * | 2018-11-29 | 2020-06-05 | 沈阳中化农药化工研发有限公司 | 一种协同杀虫杀螨组合物 |
| CN110037021A (zh) * | 2019-05-22 | 2019-07-23 | 侨昌现代农业有限公司 | 一种含联苯类增效型杀螨剂的杀螨组合物 |
| CN110367255A (zh) * | 2019-06-27 | 2019-10-25 | 山东康乔生物科技有限公司 | 包含螺甲螨酯和三氟乙基硫化物类杀虫剂的协同杀虫组合物及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114642204A (zh) | 2022-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111226955B (zh) | 一种含大环内酯类虫/螨剂的杀虫杀螨组合物 | |
| CN111226927B (zh) | 一种含有螨生长抑制剂类杀螨剂的杀虫杀螨组合物 | |
| CN111657280B (zh) | 杀虫杀螨组合物 | |
| CN101669478A (zh) | 农药组合物 | |
| CN111226945B (zh) | 一种协同杀虫杀螨组合物 | |
| CN110973153A (zh) | 含甲氰菊酯和高效氯氟氰菊酯的复合杀虫杀螨纳米水剂及其用途 | |
| CN111657281B (zh) | 一种杀虫、杀螨组合物 | |
| CN111657282B (zh) | 一种杀虫杀螨组合物 | |
| CN112244037A (zh) | 含吡虫啉和氟氯氰菊酯组合物在防治小麦金针虫中的应用 | |
| CN112704070B (zh) | 一种含拟除虫菊酯类虫/螨剂的杀虫杀螨组合物 | |
| CN114642204B (zh) | 一种含昆虫生长调节剂类虫/螨剂的杀虫杀螨组合物 | |
| CN115530170B (zh) | 一种杀虫杀螨组合物 | |
| CN113812407B (zh) | 一种含有溴虫氟苯双酰胺和四唑虫酰胺的杀虫组合物及其应用 | |
| CN111374148A (zh) | 一种含烯虫酯的杀虫组合物 | |
| CN115251062B (zh) | 一种协同杀虫杀螨组合物 | |
| WO2021078236A1 (zh) | 一种协同杀虫杀螨组合物 | |
| CN107156169A (zh) | 一种阿维菌素和高效氯氰菊酯复配乳油及其制备方法 | |
| CN113951272B (zh) | 一种含有溴虫氟苯双酰胺和氰氟虫腙的杀虫组合物及其应用 | |
| CN113519534B (zh) | 一种含溴虫氟苯双酰胺和氟啶虫酰胺的杀虫组合物及其应用 | |
| CN114642203B (zh) | 一种杀虫杀螨组合物 | |
| CN109744252B (zh) | 一种防治柑橘螨虫的增效组合物 | |
| CN108157371B (zh) | 一种用于种子包衣剂的农药组合物 | |
| CN1053084C (zh) | 氰戊菊酯、仲丁威、马拉硫磷的杀虫组合物乳油制作方法 | |
| CN107318862A (zh) | 一种杀虫组合物 | |
| CN110352966A (zh) | 一种含有戊吡虫胍的农药组合物及其用途 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |