CN114617936A - Medicinal and edible five-refined-pressure-tablet candy capable of expelling toxoplasma gondii and preparation method thereof - Google Patents

Medicinal and edible five-refined-pressure-tablet candy capable of expelling toxoplasma gondii and preparation method thereof Download PDF

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CN114617936A
CN114617936A CN202210287626.XA CN202210287626A CN114617936A CN 114617936 A CN114617936 A CN 114617936A CN 202210287626 A CN202210287626 A CN 202210287626A CN 114617936 A CN114617936 A CN 114617936A
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toxoplasma gondii
medicinal
expelling
edible
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高海东
高翼
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Jilin Deqiantang Toxoplasma Institute
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Jilin Deqiantang Toxoplasma Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/42Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
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    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
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Abstract

The invention relates to a medicinal and edible five-essence pressed candy for expelling toxoplasma and a preparation method thereof, and the medicinal and edible five-essence pressed candy is characterized by being prepared from the following raw materials in parts by weight: 30-40 parts of fructo-oligosaccharide, 18-20 parts of rhizoma polygonati, 3-5 parts of ginseng, 10-12 parts of boxthorn leaves, 6-8 parts of Chinese yam, 3-5 parts of dendrobe, 3-5 parts of honeysuckle, 3-5 parts of dandelion, 3-5 parts of liquorice, 3-5 parts of purslane, 3-5 parts of black garlic, 3-5 parts of angelica dahurica and 3-5 parts of platycodon grandiflorum; the invention has the advantages that: after the tablet candy for inhibiting and expelling toxoplasma gondii and toxoplasma gondii capsules is taken, the propagation activity of the toxoplasma gondii can be effectively inhibited, the toxoplasma gondii can be killed from a human body, and the toxoplasma gondii can be prevented from propagating in the human body.

Description

Medicinal and edible five-refined-pressure-tablet candy capable of expelling toxoplasma gondii and preparation method thereof
Technical Field
The invention relates to the technical field of functional food addition, in particular to medicinal and edible five-essence pressed candy capable of expelling toxoplasma and a preparation method thereof.
Background
Toxoplasma Gondii (Toxoplasma Gondii) is called as three-corpse worm in traditional Chinese medicine, is an animal-derived parasite spread disease, and intracellular parasites flow along with blood and reach all parts of the body to damage the brain, the heart and the eyeground, so that the immunity of people is reduced and various diseases are suffered. Mammals are main infectious sources, are closely contacted with animals, can be infected by using raw meat, raw milk, lettuce and the like, women in gestation period are very easy to be infected, most of infected women have no obvious symptoms, and part of infected women can have mild symptoms of atypical cold, such as fever, fatigue, muscular soreness and the like, and infected women can pass through a placenta to be transmitted to a fetus to cause abortion, dead fetus or malformation, and for example, children and adults also have the risk of myocarditis, encephalitis and brain softening.
It is an obligate intracellular parasite of the order coccidioideae, isosporozoa, genus toxoplasma. Its existence has been confirmed by scholars and professional organizations at home and abroad. Human and animal toxoplasma infections are widely distributed around the world, with adult infection rates of about 16-40 parts by weight, and some up to 70 parts by weight, in English and American surveys, 50-80 parts by weight, and up to 90 parts by weight for French people in continental Europe and Latin America.
The Toxoplasma gondii is infected by 25-50 weight parts, Chinese positive infection rate is 5-20 weight parts, and partial area is as high as 30 weight parts. With the increase of domestic pets, the positive infection rate is increasing dramatically. The infection of the human body has great influence and hidden danger on the health of the human body. According to the modern medical research, the anti-toxoplasma antibody detection is carried out in five items of prenatal examination before marriage, but the traditional medicine in the aspect of clinical treatment at present is the combined application of pyrimethamine and sulfadiazine, the treatment mechanism mainly comprises the inhibition of trophozoite and the control of clinical symptoms, but the traditional medicine has no effect on the cyst of toxoplasma, is easy to relapse, has long treatment period and has great side effect; antibiotic medicines such as spiramycin, clindamycin and azithromycin can be used for treatment, but the medicines have certain toxic and side effects, are required to be treated according to medical advice, are not suitable in life, and cannot solve toxoplasma infection in most of human bodies. Based on its characteristics (extremely high and extremely low temperature below can kill), there is no way to effectively kill toxoplasma gondii living bodies in the human body.
Disclosure of Invention
In view of the above problems, the present invention aims to provide a medicinal and edible five-essential oil tablet candy for expelling toxoplasma gondii and a preparation method thereof, wherein the medicinal and edible five-essential oil tablet candy is used for preparing food with a medicinal and edible food additive formula, and the activity of toxoplasma gondii is reduced by inhibiting trophozoite, so that toxoplasma gondii is expelled from cells, and then the toxoplasma gondii is expelled from human bodies in a way of being discharged from the human bodies through the own metabolic functions of the human bodies, thereby solving various problems caused by the infection of toxoplasma gondii in general people and overcoming the defects of the prior art.
The invention provides a medicinal and edible five-essence tabletted candy for expelling toxoplasma gondii, which is prepared from the following raw materials in parts by weight: 30 parts of fructo-oligosaccharide, 18-20 parts of sealwort (essence of glossy ganoderma), 3-5 parts of ginseng, 10-12 parts of boxthorn leaf (Chinese wolfberry herb), 6-8 parts of Chinese yam (essence of soil), 3-5 parts of dendrobium (mountain essence), 3-5 parts of honeysuckle, 3-5 parts of dandelion, 3-5 parts of liquorice, 3-5 parts of purslane, 3-5 parts of black garlic, 3-5 parts of angelica dahurica and 3-5 parts of platycodon grandiflorum.
The invention is preferably prepared from the following raw materials in parts by weight: 31 parts of fructo-oligosaccharide, 19 parts of rhizoma polygonati (essence of glossy ganoderma), 4 parts of ginseng, 11 parts of boxthorn leaves (Tianjing grass), 7 parts of Chinese yam (essence of soil), 4 parts of dendrobium (mountain essence), 4 parts of honeysuckle, 4 parts of dandelion, 4 parts of liquorice, 4 parts of purslane, 4 parts of black garlic, 4 parts of angelica dahurica and 4 parts of platycodon grandiflorum.
The invention also aims to provide a preparation method of the medicinal and edible five-essence tabletted candy for expelling toxoplasma gondii, which specifically comprises the following steps:
step S1: selecting raw materials, namely selecting rhizoma polygonati, ginseng, boxthorn leaves, Chinese yam, dendrobium, honeysuckle, dandelion, liquorice, purslane, black garlic, angelica dahurica and platycodon grandiflorum for preparing the five-essence tablet candy; wherein rhizoma Polygonati, Lycii folium, rhizoma Dioscoreae, herba Dendrobii, flos Lonicerae, herba Taraxaci, Glycyrrhrizae radix, herba Portulacae, black Bulbus Allii, radix Angelicae Dahuricae, and radix Platycodi are all refined decoction pieces, and are processed in the same year and strictly according to decoction piece standard, and Ginseng radix is artificially planted for more than five years;
step S2: ultrasonic cell wall breaking, ultrasonic cell crusher utilizes the dispersion effect of ultrasonic wave in liquid, makes liquid produce the effect of cavitation to make solid particle or cell tissue in the liquid break. Putting the cleaned Chinese medicinal herb refined decoction pieces into an ultrasonic cell pulverizer with power of 40KHZ of 1200W, and adding water 2; breaking cell wall at 40 deg.C for 4 min according to the proportion of medicine 1;
step S3: supercritical extraction, namely putting the raw materials prepared in the step S2 into SEF production equipment, taking CO2 as an extracting agent, producing the raw materials in an environment at the temperature lower than 25 ℃, fully dissolving the traditional Chinese medicinal materials by utilizing the relation between the dissolving capacity and the density of a supercritical fluid, and controlling the pressure range to obtain a mixed solution with the optimal proportion; then, the extracted substances are completely or basically precipitated by methods such as decompression and the like, impurities and ineffective components are removed in the process, and a high-concentration mixed solution is generated;
step S4: granulating, namely boiling and granulating the high-concentration mixed solution obtained in the step S3 by using fructo-oligosaccharide as a base material;
step S5: and (6) tabletting and forming.
The invention mainly solves the problems that:
1 at present, the effective rate of all medicinal and edible toxoplasma gondii repellents is mostly about 40 parts by weight, and the effective rate can be doubled by combining the ginseng of the invention with the boxthorn leaves and the black garlic, thereby fundamentally solving the difficult problem of repelling insects.
2. The toxoplasma gondii is used for improving immunity, and the utilization rate of all existing toxoplasma gondii products does not exceed 30 parts by weight of the absorption rate, so that the expected effect of improving immunity and further realizing toxoplasma gondii expelling cannot be achieved.
The invention utilizes continuous supplement and supplementation of homology of medicine and food to form bidirectional synchronous dynamic balance, and realizes good effect of expelling toxoplasma gondii.
The invention has the advantages and positive effects that:
1. after the tablet candy for inhibiting and expelling toxoplasma gondii and toxoplasma gondii capsules is taken, the propagation activity of the toxoplasma gondii can be effectively inhibited, the toxoplasma gondii can be killed from a human body, and the toxoplasma gondii can be prevented from propagating in the human body.
2. The invention selects pure traditional Chinese medicines as raw materials, selects proper proportion, realizes balanced collocation of the medicinal materials and has no side effect; the preparation method of the invention improves the effectiveness of the medicine under the condition of keeping the medicinal materials as far as possible from being damaged.
3. By eating the food added with the formula, the nutrition body and the cyst are removed effectively, the function of a human body is improved, the immune system damaged by the toxoplasma infection is repaired, and finally, the diseases caused by the toxoplasma infection are got rid of through the self regulation of the human body.
Detailed Description
In the following description, for purposes of explanation, numerous specific details are set forth in order to provide a thorough understanding of one or more embodiments. It may be evident, however, that such embodiment(s) may be practiced without these specific details. In other instances, well-known structures and devices are shown in block diagram form in order to facilitate describing one or more embodiments.
Example 1
The medicinal and edible five-essence tabletted candy for expelling toxoplasma gondii provided by the embodiment is prepared from the following raw materials in parts by weight: 31 parts of fructo-oligosaccharide, 19 parts of rhizoma polygonati (essence of glossy ganoderma), 4 parts of ginseng, 11 parts of boxthorn leaves (Tianjing grass), 7 parts of Chinese yam (essence of soil), 4 parts of dendrobium (mountain essence), 4 parts of honeysuckle, 4 parts of dandelion, 4 parts of liquorice, 4 parts of purslane, 4 parts of black garlic, 4 parts of angelica dahurica and 4 parts of platycodon grandiflorum.
Example 2
The medicinal and edible five-essence tabletted candy for expelling toxoplasma gondii provided by the embodiment is prepared from the following raw materials in parts by weight: 30 parts of fructo-oligosaccharide, 20 parts of sealwort (essence of glossy ganoderma), 3 parts of ginseng, 12 parts of boxthorn leaves (Tianjing grass), 8 parts of Chinese yam (essence of soil), 3 parts of dendrobium (mountain essence), 3 parts of honeysuckle, 5 parts of dandelion, 5 parts of liquorice, 3 parts of purslane, 5 parts of black garlic, 3 parts of angelica dahurica and 5 parts of platycodon grandiflorum.
Example 3
The medicinal and edible five-essence tabletted candy for expelling toxoplasma gondii provided by the embodiment is prepared from the following raw materials in parts by weight: 30 parts of fructo-oligosaccharide, 18 parts of rhizoma polygonati (essence of glossy ganoderma), 5 parts of ginseng, 10 parts of boxthorn leaves (Tianjing grass), 8 parts of Chinese yam (essence of soil), 4 parts of dendrobe (mountain essence), 5 parts of honeysuckle, 4 parts of dandelion, 4 parts of liquorice, 4 parts of purslane, 3 parts of black garlic, 5 parts of angelica dahurica and 3 parts of platycodon grandiflorum.
The application mainly aims at the problems that the toxoplasma gondii is treated by western medicines at present, has large toxic and side effects, is always treated due to side effects in the treatment process, influences the treatment effect and simultaneously generates drug resistance. These drugs can inhibit toxoplasma trophozoite, have no effect on cyst, and if used for a long time, generate drug toxicity, thus failing to achieve the purpose of curing toxoplasma. Through the formulation and research of the traditional prescription, the medicinal and edible food additive formula for expelling the toxoplasma is provided, the food with the medicinal and edible food additive formula prepared by the method is independently eaten, the activity of the toxoplasma is reduced by inhibiting a trophosome by utilizing the habit of the toxoplasma, the toxoplasma is expelled from cells, and then the toxoplasma is expelled from human bodies in a way of discharging the toxoplasma from the human bodies through the metabolic function of the human bodies, so that various problems caused by the infection of the toxoplasma by general people are solved, and the actual use requirement is met.
The coordination and complementarity among the components of the invention are as follows: the five-essence tablet candy is formed by mutually coordinating and complementing rhizoma polygonati, ginseng, boxthorn leaves, Chinese yam, dendrobium, honeysuckle, dandelion, liquorice, purslane, black garlic, angelica dahurica and platycodon grandiflorum and matching with fructo oligosaccharide.
The pharmacological drug properties of the medicinal materials are as follows:
sealwort (essence of sesame): sweet in flavor and neutral in nature. It enters spleen, lung and kidney meridians. Has effects in invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney. Can be used for treating deficiency of spleen-stomach qi, asthenia, stomach yin deficiency, xerostomia, cough with little appetite, lung deficiency, cough with excessive consumption, hemoptysis, essence and blood deficiency, soreness of waist and knees, premature gray hair, and internal heat with thirst quenching effect.
Ginseng: warm in nature, sweet, slightly bitter and slightly warm in taste. It enters spleen and lung meridians. 1. Tonifying primordial qi is suitable for collapse of primordial qi. a. Exhaustion due to qi deficiency, marked by pale complexion, palpitation, restlessness, profuse sweating, and faint pulse. b. Qi collapse and exhaustion of yang, the upper symptoms are cold sweats and cold sweats, and the limbs are not warm. It is often combined with Fu Zi. 2, tonifying spleen and lung, it can treat spleen and lung qi deficiency. a. Weakness of the spleen and stomach, poor appetite, loose stool, lassitude, weakness, vomiting, diarrhea, pale tongue and slow pulse. b. Lung qi deficiency, cough and dyspnea with debilitation, movement with debilitation, spontaneous sweating with deficient pulse, and susceptibility to wind-cold. 3, produce fluid to quench thirst, it is indicated for thirst due to body fluid consumption and diabetes. a. It is often combined with Shi Gao and Zhi mu in treating thirst due to consumption of body fluid, qi and yin deficiency due to heat, polydipsia due to fever, sweating, fatigue, and large and weak pulse. b. Internal heat, diabetes, polydipsia, rapid pulse and weakness, which is caused by internal heat and deficiency of qi and yin. It is often combined with yin-nourishing and heat-clearing herbs. 4, tranquilizing mind and improving intelligence, it is indicated for restlessness, insomnia and amnesia caused by deficiency of qi and blood, and often combined with heart-nourishing and tranquilizing herbs. In addition, it is indicated for impotence due to blood deficiency and exuberance of healthy qi due to qi-hyperactivity and blood generation, self-strengthening of qi-hyperactivity and yang-qi, and strengthening healthy qi to eliminate pathogens.
Boxthorn leaf (chinese wolfberry herb): tonify liver and kidney, promote the production of body fluid to quench thirst, dispel wind and remove dampness, activate blood and resolve stasis. It is indicated for fever due to asthenia, polydipsia, conjunctival congestion, blurred vision, pain, nebula nyctalopia, metrorrhagia, leukorrhagia, sores and swelling due to heat-toxin.
Chinese yam (essence of soil): sweet, warm, mild and nontoxic. Mainly treats the diseases of impairment, deficiency, shortness of breath, cold and heat, evil qi removal, middle warmer tonifying, qi and strength benefiting, muscle growth and yin strengthening. It can be taken for a long time, and has effects of improving hearing and eyesight, reducing weight, and prolonging life. This meridian. Mainly treating head and face wandering wind, head wind and eye glare, descending qi, stopping lumbago, treating asthenia, marasmus, filling five internal organs, and removing dysphoria. And (6) recording. Tonify five strains and seven injuries, remove cold wind, calm heart spirit, tranquilize mind, tonify heart-qi deficiency, and open up heart holes for recording. And (6) screening. Strengthen tendons and bones, direct excretion of essence and amnesia. Daming. Replenishing kidney qi, strengthening spleen and stomach, stopping diarrhea, resolving phlegm and moistening skin and hair. Shizhen. The swelling and toxicity of raw pounded plaster can be dissipated. The process is Shaheng.
Dendrobe (mountain extract): mainly used for reinforcing stomach and promoting fluid production, nourishing yin and clearing heat. Can be used for treating yin deficiency and fluid deficiency, dry mouth, polydipsia, anorexia, retching, asthenic fever after disease, and dim and unclear vision.
Honeysuckle flower: sweet and cold in nature, entering lung and stomach meridians, and clearing away heat and toxic materials. It can be used for treating fever due to affection of exogenous wind-heat or epidemic febrile disease, heatstroke, toxic heat, dysentery, carbuncle, furuncle, pharyngitis, and various infectious diseases.
Dandelion: bitter and sweet, cold in nature, entering liver and stomach meridians, clearing away heat and toxic material, inducing diuresis and dissipating nodulation. It can be used for treating acute mastitis, lymphadenitis, lymphoid tuberculosis, furunculosis, acute conjunctivitis, common cold with fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, and urinary tract infection.
Licorice root: sweet in taste and neutral in nature, and has the effects of invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the medicines.
Purslane: sour and cold, entering liver and large intestine meridians, clearing away heat and toxic material, cooling blood and stopping bleeding, and stopping dysentery.
Black garlic: the powerful antioxidant effect of black garlic is the key reason for the good practical effect of black garlic on more symptoms. Enhancing the efficacy of the immune system and adjusting the blood sugar level with super-strong force.
Radix angelicae: pungent and warm in flavor, warm in nature, entering lung, spleen and stomach channels, relieving exterior syndrome and dispelling cold, dispelling pathogenic wind and relieving pain, dredging nasal orifice, eliminating dampness and stopping leukorrhagia, relieving swelling and pus, dispelling pathogenic wind and relieving itching.
Balloon flower: bitter and pungent in flavor, neutral in nature, entering lung meridian, dispersing lung qi, relieving sore throat, eliminating phlegm, and expelling pus.
The first, second and third formulas of the above embodiments have the same operation steps, and comprise the following steps:
step S1: selecting raw materials, namely selecting rhizoma polygonati, ginseng, boxthorn leaves, Chinese yam, dendrobium, honeysuckle, dandelion, liquorice, purslane, black garlic, angelica dahurica and platycodon grandiflorum for preparing the five-essence tablet candy; wherein rhizoma Polygonati, Lycii folium, rhizoma Dioscoreae, herba Dendrobii, flos Lonicerae, herba Taraxaci, Glycyrrhrizae radix, herba Portulacae, black Bulbus Allii, radix Angelicae Dahuricae, and radix Platycodi are refined decoction pieces, and processed according to the decoction piece standard in the same year, and Ginseng radix is artificially planted to obtain Ginseng radix with more than five years old;
step S2: ultrasonic cell wall breaking, ultrasonic cell crusher utilizes the dispersion effect of ultrasonic wave in liquid, makes liquid produce the effect of cavitation to make solid particle or cell tissue in the liquid break. Putting the cleaned Chinese medicinal herb refined decoction pieces into an ultrasonic cell pulverizer with power of 40KHZ of 1200W, and adding water 2; breaking cell wall at 40 deg.C for 4 min according to the proportion of medicine 1;
step S3: supercritical extraction, namely putting the raw materials prepared in the step S2 into SEF production equipment, taking CO2 as an extracting agent, producing the raw materials in an environment at the temperature lower than 25 ℃, fully dissolving the traditional Chinese medicinal materials by utilizing the relation between the dissolving capacity and the density of a supercritical fluid, and controlling the pressure range to obtain a mixed solution with the optimal proportion; then, the extracted substances are completely or basically precipitated by methods such as decompression and the like, impurities and ineffective components are removed in the process, and a high-concentration mixed solution is generated;
step S4: granulating, namely boiling and granulating the high-concentration mixed solution obtained in the step S3 by using fructo-oligosaccharide as a base material;
step S5: and (6) tabletting and forming.
The clinical effect comparison test report of the invention:
first, diagnosis standard
According to the modern medicine, natural medicine and nutriology:
people carrying toxoplasma gondii have fatigue and low immune function;
people with serious infection and human bodies have cough, fever, dizziness, headache and abdominal pain.
II, bringing into clinic:
all the above symptoms can be clinically treated.
Thirdly, taking method and dosage:
the administration method comprises the following steps: can be taken orally or chewed
Taking: twice daily: one in the morning and evening, 1000-2000 mg each time (1-2 tablets)
Fourthly, efficacy standard:
the method has the following advantages: the infection symptom is improved after taking a course of treatment.
The effect is shown: after taking the medicine for two courses of treatment, the infection symptoms are obviously improved.
And (3) healing: after taking for 2-3 courses of treatment, the joint is powerful, the immunity is enhanced, and the fatigue is resisted.
And (4) invalidation: taking for 1-2 treatment courses, and no symptom relief or improvement.
Fifth, statistics of clinical results:
the infected person: 12 persons; slight discomfort; wherein: cure 9 patients and show 3 patients.
31 severely infected persons; cough, fever, dizziness, headache, abdominal pain: 16 persons; after 3 courses of treatment, 12 patients can be cured, and 4 patients can be treated obviously.
Cough: 11 persons; after 3 courses of treatment, 5 patients are cured, and 6 patients are treated.
Fever is caused: 4 persons; all healed in 3 courses of treatment and can move freely.
Clinical statistics were as follows: the effective rate is as follows: 100 parts by weight; the display efficiency is as follows: 30 parts by weight; the cure rate is as follows: 70 parts by weight; inefficiency: and no display.
The invention is utilized to carry out experiments on animals infected with toxoplasma gondii, and the measured comparative data further proves that the medicinal and edible five-essence tablet candy has special efficacy and function.
The following list of typical cases further demonstrates the efficacy of the present invention:
medical record 1: male, 49 years old
The main points are as follows: dizziness, headache, and weakness of feet, and people feel well tired when feeling dry, and the people who see the hospital have a little time to eat more and better, strengthen nutrition and do not check out any problem.
Physical examination: blood staining test, detection of lgg antibody, indirect hemagglutination test: the following are found: infection with Toxoplasma gondii.
Treatment: after taking the product of the invention in the example 1, the examination was repeated 40 days after 1 tablet (1000mg) in the morning and 2 tablets (2000mg) in the evening (before sleeping).
And (4) rechecking after 40 days: no dizziness and headache, powerful walking, full spirit, blood staining test, lgg antibody detection, indirect blood coagulation test, recovery and recovery.
Medical record 2: a woman, age 53
The main complaints are: cough and abdominal pain often occur, and no disease can be detected in hospitals.
Physical examination: blood staining test, detection of lgg antibody, indirect hemagglutination test. Diagnosis: toxoplasma gondii infection.
Treatment: after taking the product of the invention in the example 2, 1 tablet (1000mg) in the morning and 2 tablets (2000mg) before sleeping at night, the examination is repeated after two months.
After 3 treatment courses, reexamination is carried out:
cough and abdominal pain are completely improved, walking is forceful, and the patient can be cured after taking the medicine for 2 courses.
And (4) proposing: the dosage for health promotion is 1 tablet in the morning and evening respectively.
Medical record 3: 65 years old for a male
The main complaints are: frequent dizziness and headache are caused, and when a doctor visits a hospital, the disease is a blood disease, the patient takes the medicine for three years, and the medicine is old and easy to have fever and hypodynamia.
Physical examination: blood staining test, detection of lgg antibody, indirect hemagglutination test.
Diagnosis: severe toxoplasma infection.
Treatment: after taking the product of the invention in example 3, 2 tablets (1000mg X2) are taken in the morning and 2 tablets (1000mg X2) are taken before the night sleep for 80 days
And (4 treatment courses).
And (4) rechecking: the toxoplasma gondii infection is absent and basically normal.
Fever, dizziness and headache are completely relieved.
The patients are recovered after 5 courses of treatment and follow-up service.
The tablet for inhibiting and expelling toxoplasma gondii and toxoplasma gondii capsule bodies, which is continuously used by the invention, can effectively inhibit the propagation activity of the toxoplasma gondii, thereby killing the toxoplasma gondii in a human body, preventing the toxoplasma gondii from propagating in the human body, preventing the infection between people and reducing the diseases brought by the toxoplasma gondii.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (3)

1. The medicinal and edible five-essence tabletted candy for expelling toxoplasma gondii is characterized by being prepared from the following raw materials in parts by weight: 30-40 parts of fructo-oligosaccharide, 18-20 parts of rhizoma polygonati, 3-5 parts of ginseng, 10-12 parts of boxthorn leaves, 6-8 parts of Chinese yam, 3-5 parts of dendrobe, 3-5 parts of honeysuckle, 3-5 parts of dandelion, 3-5 parts of liquorice, 3-5 parts of purslane, 3-5 parts of black garlic, 3-5 parts of angelica dahurica and 3-5 parts of platycodon grandiflorum.
2. The medicinal and edible five-essential tabletted candy for expelling toxoplasma according to claim 1, which is characterized by being prepared from the following raw materials in parts by weight: 31 parts of fructo-oligosaccharide, 19 parts of rhizoma polygonati, 4 parts of ginseng, 11 parts of boxthorn leaves, 7 parts of Chinese yam, 4 parts of dendrobium, 4 parts of honeysuckle, 4 parts of dandelion, 4 parts of liquorice, 4 parts of purslane, 4 parts of black garlic, 4 parts of angelica dahurica and 4 parts of platycodon grandiflorum.
3. A preparation method of medicinal and edible five-essence tabletted candy for expelling toxoplasma gondii is characterized by comprising the following steps:
step S1: selecting raw materials, namely selecting rhizoma polygonati, ginseng, boxthorn leaves, Chinese yam, dendrobium, honeysuckle, dandelion, liquorice, purslane, black garlic, angelica dahurica and platycodon grandiflorum for preparing the five-essence tablet candy; wherein rhizoma Polygonati, Lycii folium, rhizoma Dioscoreae, herba Dendrobii, flos Lonicerae, herba Taraxaci, Glycyrrhrizae radix, herba Portulacae, black Bulbus Allii, radix Angelicae Dahuricae, and radix Platycodi are all refined decoction pieces which are produced in the same year, and processed strictly according to decoction piece standard, and Ginseng radix is artificially planted for more than five years;
step S2: ultrasonic cell wall breaking, ultrasonic cell crusher utilizes the dispersion effect of ultrasonic wave in liquid, makes liquid produce the effect of cavitation to make solid particle or cell tissue in the liquid break. Putting the cleaned Chinese medicinal herb refined decoction pieces into an ultrasonic cell pulverizer with power of 40KHZ of 1200W, and adding water 2; breaking cell wall at 40 deg.C for 4 min according to the proportion of medicine 1;
step S3: supercritical extraction, namely putting the raw materials prepared in the step S2 into SEF production equipment, taking CO2 as an extracting agent, producing the raw materials in an environment at the temperature lower than 25 ℃, fully dissolving the traditional Chinese medicinal materials by utilizing the relation between the dissolving capacity and the density of a supercritical fluid, and controlling the pressure range to obtain a mixed solution with the optimal proportion; then, the extracted substances are completely or basically precipitated by methods such as decompression and the like, impurities and ineffective components are removed in the process, and a high-concentration mixed solution is generated;
step S4: granulating, namely boiling and granulating the high-concentration mixed solution obtained in the step S3 by using fructo-oligosaccharide as a base material;
step S5: and (6) tabletting and forming.
CN202210287626.XA 2022-03-23 2022-03-23 Medicinal and edible five-refined-pressure-tablet candy capable of expelling toxoplasma gondii and preparation method thereof Pending CN114617936A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498699A (en) * 2018-06-20 2018-09-07 北京刚地源弓形虫病医学研究院 A kind of formula wine and preparation method thereof for driving away toxoplasma
CN108902968A (en) * 2018-06-20 2018-11-30 北京刚地源弓形虫病医学研究院 A kind of integration of drinking and medicinal herbs food addition formula and preparation method thereof for driving away toxoplasma
CN109646571A (en) * 2017-10-12 2019-04-19 王广民 Public English gold oral solution and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109646571A (en) * 2017-10-12 2019-04-19 王广民 Public English gold oral solution and preparation method thereof
CN108498699A (en) * 2018-06-20 2018-09-07 北京刚地源弓形虫病医学研究院 A kind of formula wine and preparation method thereof for driving away toxoplasma
CN108902968A (en) * 2018-06-20 2018-11-30 北京刚地源弓形虫病医学研究院 A kind of integration of drinking and medicinal herbs food addition formula and preparation method thereof for driving away toxoplasma

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