CN114609401A - Urine sample detects and examines after-treatment system - Google Patents

Urine sample detects and examines after-treatment system Download PDF

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Publication number
CN114609401A
CN114609401A CN202210274615.8A CN202210274615A CN114609401A CN 114609401 A CN114609401 A CN 114609401A CN 202210274615 A CN202210274615 A CN 202210274615A CN 114609401 A CN114609401 A CN 114609401A
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sample
detection
equipment
treatment
test tube
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王朝亮
李云龙
郭一铭
毕天祥
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First Affiliated Hospital of Zhengzhou University
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First Affiliated Hospital of Zhengzhou University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L11/00Methods specially adapted for refuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04Heat
    • A61L2/06Hot gas
    • A61L2/07Steam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/10Ultraviolet radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26Accessories or devices or components used for biocidal treatment
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0437Cleaning cuvettes or reaction vessels

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Abstract

The invention relates to a urine sample detection and post-detection processing system, which comprises a urine detection system and a post-detection processing system; the urine detection system comprises test strip sorting equipment, sample pretreatment equipment and urine sample detection equipment which are connected in sequence; the post-detection treatment system comprises a liquid waste treatment system and a solid waste treatment system, wherein the liquid waste treatment system comprises a urine sample post-detection treatment device, and the solid waste treatment system comprises a test strip post-detection treatment device and a test strip post-detection treatment device; the automatic urine monitoring system and the post-detection treatment system are organically combined together, so that various solid and liquid wastes in urine detection can be treated in time while the urine sample detection can be efficiently treated in batches, the leakage risk caused by untimely or improper treatment of harmful substances is avoided, and the detection environment and detection personnel are protected.

Description

Urine sample detects and examines after-treatment system
Technical Field
The invention belongs to the field of medical detection equipment, and particularly relates to a urine sample detection and post-detection processing system.
Background
Urine is mainly treated by the functions of blood filtration, reabsorption and the like through the kidney, and is finally excreted through the urethra to form a metabolite; urine examination is a common medical detection mode, and comprises conventional urine analysis, detection of visible components in urine, quantitative determination of urine protein components, and urease determination; since the discharge of urine has important value for the balance of water, acid, alkali and electrolyte of human body and has inseparable relation with blood circulation, organ function and tissue stability, the analysis of the quantity, property and composition of urine has important value for clinical diagnosis, judgment of curative effect and prognosis effect, etc., and the urine of patients is often examined and measured in clinic, and a large amount of urine samples are required to be detected and processed in hospitals every day.
The traditional urine test methods can be mainly divided into three types: visual, microscopic, and chemical inspections; with the development of science and technology, the urine chemical analyzer gradually replaces the traditional inspection method, and is becoming one of the main tools in the urine inspection field due to higher inspection efficiency and higher detection accuracy; however, the urine detection by the urine chemical analyzer has the problems that more consumables are difficult to process, the waste urine sample accumulation is easy to cause the problem that the waste urine sample cannot be processed in time due to non-personnel real-time operation, and the like; how to design a set of new urine sample detecting system, make it can be when the high-efficient urine sample that detects automatically carry out timely innocent treatment with the abandonment consumptive material and the abandonment sample etc. that produce in detecting, be the key problem of maintaining the testing environment, protection measurement personnel and instrument and equipment health safety.
Disclosure of Invention
The invention aims to provide a urine sample detection and post-detection treatment system which can perform harmless treatment on waste generated in detection in time.
Based on the purpose, the invention adopts the following technical scheme:
a urine sample detection and post-detection processing system comprises a urine detection system and a post-detection processing system which are sequentially connected; the urine detection system comprises sample pretreatment equipment, and test strip sorting equipment is arranged in a manner of being matched with the sample pretreatment equipment; the sample pretreatment equipment is connected with urine sample detection equipment, and the urine sample detection equipment comprises a urine sample analyzer and an optical analyzer; the post-detection treatment system comprises a liquid waste treatment system and a solid waste treatment system, wherein the liquid waste treatment system comprises urine sample post-detection treatment equipment, and the solid waste treatment system comprises test strip post-detection treatment equipment and test strip post-detection treatment equipment; the post-treatment equipment for urine sample detection and the post-treatment equipment for test tube detection are both connected with the sample pretreatment equipment, and the post-treatment equipment for test strip detection is connected with the urine sample detection equipment.
Preferably, the sample pretreatment equipment comprises a sample table and a treatment bin, wherein the sample table is arranged in front of the treatment bin; a transfer groove is arranged on the sample table and is a closed rotary groove in a shape of a Chinese character kou; a transfer driving mechanism matched with the transfer groove is arranged in the sample table, and a sample transfer mechanism matched with the transfer groove is arranged on the processing bin; the sample transfer mechanism comprises a sampling needle, and the sampling needle is arranged on the sampler; the sampler is connected with a sample separating mechanism through a pipeline, and a test paper strip conveying mechanism is arranged in a way of matching with the sample separating mechanism; still be provided with the test tube arm on handling the storehouse, the test tube arm sets up on the test tube translator.
Preferably, the sample separating mechanism comprises a sample separating dropper, and the sample separating dropper is connected with the sampler through a pipeline; a sample pre-treatment device is internally provided with a sample separation cavity, the top of the sample separation cavity is provided with a sliding sample separation seat, and a sample separation dropper is arranged at the bottom of the sliding sample separation seat; a telescopic table is arranged on the sliding sample separating seat, and a peristaltic pump is arranged in the sliding sample separating seat; the bottom of the sample separation cavity is provided with a test strip conveying mechanism, the test strip conveying mechanism comprises a test strip conveying belt, the starting end of the test strip conveying belt is connected with test strip sorting equipment, and the terminal end of the test strip conveying belt is connected with urine sample detection equipment.
Preferably, the test tube manipulator comprises a telescopic electric cylinder, and a test tube clamping frame is arranged at the bottom end of the telescopic electric cylinder; the test tube mechanical arm is arranged at the bottom of the test tube shifter, and a shifting driving mechanism is arranged on the test tube shifter and comprises a shifting motor and a shifting wheel set; be provided with in the sample pretreatment equipment with shift wheelset complex shift the groove, shift the inboard terminal below in groove and be provided with the test tube conveyer belt coordinately, the terminal point end and the test tube of test tube conveyer belt examine the post-processing equipment and be connected.
Preferably, the urine sample analyzer comprises a test strip positioning mechanism, and the test strip positioning mechanism is connected with the test strip conveyor belt in a matching way; the test strip positioning mechanism comprises a positioning conveyor belt, and a plurality of test strip positioning points are arranged on the positioning conveyor belt; a fixed-track urine sample analysis probe is arranged in the urine sample analyzer, is arranged above the test strip positioning mechanism and is matched with the test strip positioning point; the optical analyzer is arranged at the tail end of the test strip positioning mechanism and comprises an optical analysis lens, and the optical analysis lens is matched with the test strip positioning point on the positioning conveyor belt.
Preferably, the post-processing equipment for urine sample detection comprises high-temperature ultraviolet processing equipment, wherein a processing cavity is arranged in the high-temperature ultraviolet processing equipment, and an ultraviolet generator and a heater are arranged in the processing cavity; the sample pretreatment equipment is internally provided with a shunt pump, the shunt pump is arranged on a pipeline connecting the sampler and the sample separation mechanism, and the shunt pump is connected to the treatment cavity through a liquid discharge pipeline.
Preferably, the post-processing equipment for urine sample examination comprises a high-temperature high-pressure steam bin, wherein a high-pressure steam generator is arranged at the bottom of the high-temperature high-pressure steam bin, and the top of the high-pressure steam generator is connected with a processing bin; the treatment bin is provided with liquid inlet, leakage fluid dram and gas vent, and the liquid inlet is connected to high temperature ultraviolet ray treatment facility through flowing back pipeline, and the leakage fluid dram is connected to sewer pipe, and the gas vent is connected to exhaust gas purification equipment.
Preferably, the tail end of a positioning conveyor belt in the urine sample detection device is connected with a test strip transfer conveyor belt, and the test strip transfer conveyor belt is connected to the high-temperature ultraviolet treatment device; a test strip treatment cavity is arranged in the high-temperature ultraviolet treatment equipment, and an ultraviolet generator and a heater are arranged in the test strip treatment cavity; a leakage-proof closed pipeline is arranged between the urine sample detection equipment and the high-temperature ultraviolet treatment equipment, and the test strip transfer conveyor belt is arranged in the leakage-proof closed pipeline; the test strip treatment cavity in the high-temperature ultraviolet treatment equipment is connected to the waste test strip collecting area through a waste conveying belt.
Preferably, the post-test tube treatment device comprises a test tube washing machine, and the test tube washing machine is arranged on the test tube conveying belt; the test tube washing machine is connected to high-temperature ultraviolet treatment equipment through a test tube conveyor belt, a test tube treatment cavity is arranged in the high-temperature ultraviolet treatment equipment, and an ultraviolet generator and a heater are arranged in the test tube treatment cavity; the tube treatment chamber in the high temperature ultraviolet treatment device is connected to the waste tube collection zone by a waste conveyor belt.
Preferably, the sample preprocessing equipment is provided with an operation table, and the operation table comprises a touch control screen; the touch control operation screen controls the urine sample detection equipment in a signal connection mode, and the urine sample detection equipment is connected with a data processing terminal in the signal connection mode.
The invention has the following beneficial effects:
the invention relates to a comprehensive urine sample detection and post-detection treatment system, which can intelligently and automatically treat urine samples, drop the urine samples on urine detection test strips in a classified manner, and send the urine samples into urine sample detection equipment for automatic detection; the whole process of the detection process is tracked, the detection result is automatically sorted and can be output through a data processing terminal; various waste consumables such as used test strips and test tubes generated in the detection process, remaining urine samples and the like which are not completely used can be subjected to harmless treatment in time during the detection process; the whole process is closed without leakage in the treatment process, and the risk of leakage of harmful substances in the transfer process is avoided.
According to the invention, a mode of high-temperature disinfection and ultraviolet irradiation disinfection is adopted in the post-inspection treatment step, and high-temperature ultraviolet treatment equipment is arranged, so that no extra consumable material is used in the treatment process, and no secondary waste is generated; after the high-temperature ultraviolet treatment equipment, a step of high-temperature high-pressure steam treatment is also set for the urine sample, and harmful bacteria, viruses and the like possibly existing in the urine sample are further sterilized, so that toxic and harmful substances contained in the urine sample can be thoroughly removed; the urine sample is cooled and separated from liquid and gas after being sterilized twice, and is continuously led into subsequent waste gas and waste liquid treatment equipment, a sewer pipeline can be introduced into the further treatment equipment or the further treatment equipment can be discharged into the atmosphere, and harmless treatment of the urine sample is really realized.
According to the invention, urine sample detection and post-detection treatment equipment are organically combined in the same system, so that harmless treatment of waste to be treated can be ensured at the first time; the whole treatment process keeps a totally-enclosed structure, so that leakage pollution possibly occurring in the treatment process is avoided; according to the invention, the self-cleaning structure is arranged in the sample pretreatment equipment, so that the internal pipeline can be automatically cleaned after sampling and sample division are completed each time, the cleanness of the sampler and the pipeline during sampling each time is ensured, and the problem of inaccurate detection result caused by pollution of samples in multiple times of sampling is avoided.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a top view of the present invention;
FIG. 3 is a schematic view of the overall structure of embodiment 1 of the present invention;
FIG. 4 is a schematic structural view of a test tube rack in example 1 of the present invention;
FIG. 5 is a schematic view of the bottom structure of a test tube rack in example 1 of the present invention;
FIG. 6 is a schematic view of an internal structure of a sample pretreatment apparatus in embodiment 1 of the present invention;
FIG. 7 is a schematic view showing the internal structure of a high-temperature ultraviolet ray treatment apparatus in embodiment 2 of the present invention;
FIG. 8 is a schematic structural diagram of a connection between a sample pre-processing apparatus and a post-detection processing system according to embodiment 3 of the present invention;
FIG. 9 is a flow chart of the present invention.
In the figure: a sample pre-treatment apparatus 1; a liquid storage tank 11; a touch screen 12; a sampling needle 13; a test tube robot arm 14; a rotary slide groove 15; a sampling needle motor 16; a sliding sample separating seat 17; a sample separation dropper 171; a waste liquid collector 18; a liquid delivery pipe 19; the test strip sorting equipment 2; a test strip conveyor belt 21; a urine sample detection device 3; a high-temperature ultraviolet treatment apparatus 4; a urine treatment chamber 41; a strip processing chamber 42; a cuvette processing chamber 43; an ultraviolet lamp tube 44; a heater 45; a conveyor belt 46; an outlet 47; a urinary chamber heating layer 48; a connecting pipe 49; a high-temperature high-pressure steam bin 5; a waste liquid pipe 51; a data processing terminal 6; a test tube 7; a test tube rack 71; a drive projection 72; the closed conveyor belt 8; a test tube washing machine 81; and (6) a test strip 9.
Detailed Description
Example 1
As shown in fig. 1, the present embodiment is a urine sample detection-level post-detection processing system, which specifically includes two parts, namely a urine detection system and a post-detection processing system; the urine detection system comprises a test strip sorting device 2, a sample pretreatment device 1 and a urine sample detection device 3 which are connected in sequence; the post-detection treatment system comprises a high-temperature ultraviolet treatment device 4 respectively connected with the sample pre-treatment device 1 and the urine sample detection device 3, and a high-temperature high-pressure steam bin 5 connected with the high-temperature ultraviolet treatment device 4 through a connecting pipeline 49; the urine detection system is also provided with a data processing terminal 6 which is connected with each device in the urine detection system and used for processing each data detected in the urine detection device.
As shown in fig. 3, the test strip sorting device 2 is used for collecting test strips 9, and arranging the test strips 9 at certain intervals and in sequence; the test strips 9 are put in through a throwing-in opening at the top of the test strip sorting equipment 2 and are arranged and stacked in the test strip sorting equipment 2, so that the test strips 9 are arranged in order in a transverse arrangement mode on the test strip conveyor belt 21; each test strip 9 has a certain interval distance and is conveyed to the sample pretreatment device 1 in batches in a certain number in a group form through the test strip conveyor belt 21; in this embodiment, the test tube rack 71 is a quintuplet test tube structure, and the sample pretreatment device 1 also adopts a corresponding internal structure, so the test strip sorting device 2 should arrange the test strips 9 in a five-in-one manner.
As shown in fig. 3, an opening is provided at the bottom of the side surface of the sample pretreatment apparatus 1, and the opening is matched with the test strip conveyor belt 21, so that the test strip conveyor belt 21 can enter the sample pretreatment apparatus 1 from the opening; a sample dividing cavity is arranged in the sample pretreatment equipment 1, the sample dividing cavity penetrates through the left end and the right end of the sample pretreatment equipment 1 and is connected with the opening, and the test strip conveyor belt 21 passes through the sample pretreatment equipment 1 in a left-right transverse mode through the sample dividing cavity; the sample separating mechanism for dropping the urine sample in each detection area on the test paper strip 9 is arranged in the sample separating cavity in the sample preprocessing device 1, so that the test paper strip 9 placed on the test paper strip conveyor belt 21 can receive the urine sample to be detected through the sample separating mechanism when passing through the sample separating cavity, and further continuously transmits the urine sample to the urine sample detection device 3 through the test paper strip conveyor belt 21 for detection.
The sample pretreatment device 1 comprises two parts, namely a sample table for bearing a sample and a test tube, and a treatment bin containing a sample pretreatment mechanism, wherein the sample table is arranged in front of the treatment bin, as shown in fig. 3; a rotary sliding groove 15 is formed in the top of the sample table, and a plurality of test tube racks 71 can be placed on the rotary sliding groove 15; in this embodiment, five test tubes 7 may be placed in the test tube rack 71, and each test tube 7 is placed in the test tube rack 71 in parallel side by side, as shown in fig. 4; since the size of the test tube rack 71 is matched with the size of the rotary sliding groove 15, the test tube rack 71 can be placed in the rotary sliding groove 15 and slide along the track of the rotary sliding groove 15; the test tube rack 71 can slide in a rotary sliding groove 15 in a rotary manner, and when the test tube rack slides to the outside, the test tube rack 7 can be used for placing a new sample test tube; when sliding to the inner side, the urine sample pretreatment device can be matched with a sampling needle 13 arranged at the top of the treatment bin, so that the urine sample can be conveniently separated and pretreated in the sample pretreatment device 1 sucked by the sampling needle 13; after the sampling needle 13 finishes sampling, the test tube rack 71 continues to slide forward, and the test tube 7 can be taken out of the test tube rack 71 through the test tube mechanical arm 14 and sent to a test tube conveyor belt in the sample pretreatment device 1, and then enters a subsequent test tube cleaning step through the test tube conveyor belt.
A transfer driving mechanism is arranged in the sample table and comprises a transfer driving motor set and a driving wheel set; the driving wheel set is arranged at the bottom side of the inner part of the rotary sliding groove 15 and is matched with the bottom of the test tube rack 71; the bottom of the test tube rack 71 is provided with a transmission protrusion 72, the transmission protrusion 72 comprises a plurality of groups of protrusion strips which are horizontally and vertically arranged, and the horizontal protrusions and the vertical protrusions are arranged in a staggered manner, as shown in fig. 5; the transmission protrusion 72 at the bottom of the test tube rack 71 is matched with a driving wheel set in the transfer driving mechanism, and a transmission gear structure matched with the transmission protrusion 72 is arranged on the driving wheel set, so that the test tube rack 71 can automatically slide under the driving of the driving wheel set; the driving direction of the driving wheel set is related to the position in the rotary sliding groove 15 where the driving wheel set is located, and the driving directions of all the driving wheel sets are the same along the sliding direction of the rotary sliding groove 15, namely, the driving wheel sets are arranged in the counterclockwise direction in the embodiment; when the driving directions of all the driving wheel sets can be connected with each other to form a closed loop, the test tube rack 71 can be driven to perform anticlockwise transfer sliding around the corresponding directions; at the corner, the test tube rack 71 is firstly sent to the corner of the rotary sliding groove 15 by the driving wheel set at the previous section, and after the driving is stopped, the test tube rack 71 is pulled out from the corner by the driving wheel set at the next section; since the horizontal and vertical transmission protrusions 72 are staggered, the driving in two directions can be respectively received without interference, and the locking is not caused.
The urine sample treatment part of the sample pretreatment apparatus 1 in this embodiment is shown in FIG. 6; the processing bin is provided with an outward protruding part at the positions of the test tube rack 71 on the sample table and the top of the test tube 7 for drinking, and the bottom of the position is provided with a sampling needle 13; the sampling needle 13 is arranged at the bottom of the sampler, and the sampler is driven by a sampling needle motor 16 and can be lifted up and down; in this embodiment, the sampling needles are arranged side by side in groups of five, and the arrangement intervals of the sampling needles are matched with the intervals of the test tubes on the test tube rack 71, so that the sampling needles 13 can simultaneously sample five test tubes in one test tube rack 71 when sampling is performed below; the tail part of each sampling needle 13 is connected to a peristaltic pump in the sliding sample dividing seat 17 through a pipeline, and the peristaltic pump is driven through the pipeline to provide suction force for sucking the urine sample for each sampling needle 13.
A sample dropping tube 171 is arranged at the bottom of the sliding sample separating seat 17; the sample separation dropper 171 is connected with a peristaltic pump, and the peristaltic pump can pump the urine sample into the sample separation dropper 171 through a pipeline; the bottom end of the sample dividing dropper 171 extends into the sample dividing cavity and is matched with the test strip conveyor belt 21 in the sample dividing cavity, so that the sample dividing dropper 171 can be matched with the test strip 9 on the test strip conveyor belt 21 to drop the urine sample into each area on the test strip 9; the sliding sample separating seat is of a slidable structure, and a sample separating dropper 171 connected with the bottom of the sliding sample separating seat can slide along with the sliding sample separating seat; the sample dropping tube 171 can move back and forth along the width direction of the test strip conveyor belt 21 to drop the urine sample to each area on the test strip 9; a waste liquid collector 18 is arranged at the bottommost part and the outermost part of the sample separation cavity; the aliquot dropper 171 can drain excess urine sample into the waste collector 18 and through the transfer line 19 to a subsequent post-examination treatment system.
The top of the sample pretreatment equipment 1 is provided with a liquid storage tank 11, the liquid storage tank 11 can be linked with a water source to provide a clean water source for self-cleaning of the equipment, and meanwhile, a cleaning agent bin is also arranged in the liquid storage tank 11 and can store cleaning agent so as to facilitate automatic use during self-cleaning; the liquid storage tank 11 is connected to a peristaltic pump in the sliding sample separation seat 17 through a pipeline, as shown in FIG. 6; the peristaltic pump can pump a clean water source or a cleaning agent in the liquid storage tank 11 into an internal pipeline of the sample pretreatment device 1, and the pipeline, the sampling needle 13 and the sample dividing dropper 171 are cleaned; waste water generated in the self-cleaning can also be discharged into the waste liquid collector 18 through the pipette 171 and discharged through the liquid conveying pipe 19.
After the sample separation is finished, the test strip 9 for obtaining the urine sample is continuously conveyed forwards under the driving of the test strip conveyor belt 21; after leaving the sample pretreatment device 1, the sample enters a closed conveyor belt 8 enclosed by a housing; the closed conveyor belt 8 is relatively isolated from the outside air, so that urine sample components on the test strip 9 can be prevented from leaking, and the cleanness and sanitation of the outside environment can be kept; the test strip 9 is conveyed into the urine sample detection device 3 through the closed conveyor belt 8; the urine sample detection device 3 comprises a urine sample analyzer which comprises a test paper strip positioning mechanism; the test strip positioning mechanism comprises a positioning conveyor belt, and a plurality of test strip positioning points are arranged on the positioning conveyor belt; a plurality of side-by-side orbit determination urine sample analysis probes are arranged above the positioning conveyor belt, and can move along the length direction of the test strip 9 to respectively detect and analyze a plurality of detection areas on the test strip 9; after the probe detection is finished, the test strip 9 is driven by the positioning conveyor belt to move into the optical analyzer, and an optical analysis lens matched with the positioning conveyor belt is arranged in the optical analyzer, so that the optical analysis area on the test strip 9 can be shot and automatically analyzed; after the analysis step is completed, the test strip 9 passes through the closed conveyor belt 8 again and is sent to a subsequent post-detection treatment system for post-detection harmless treatment.
The embodiment is also provided with a data processing terminal 6 for collecting and processing various data appearing in the detection; the touch screen 12 is arranged on the top of the front side of the sample preprocessing equipment 1, so that information of each sample can be input while sampling is carried out, and an input result can establish a detection file for the sample at the data processing terminal 6; in the detection process, each generated detection data is recorded along with a detection file to which the sample belongs and is stored in the data processing terminal 6 for detection personnel to search, browse, export, print and the like; the data processing terminal 6 is connected to the urine sample detection device 3 by signal connection, and can collect the detection results including data results and image information from the urine sample detection device 3 in time; for optically analyzed image information, the data processing terminal 6 can algorithmically calculate the assay, complete the detection of the sample image, and generate a report.
The detection personnel can carry out direct control to each equipment through the touch screen 12 that sets up in sample preprocessing equipment 1 department, including setting for detection data and instruction, establish the detection data archives to can in time collect the behavior of each equipment through data processing terminal 6, assign the instruction to entire system, control system's behavior for this basis.
In this example, the flow of steps that are passed when performing the urine sample detection operation is shown in FIG. 9: before detection, a urine sample and a test strip 9 for detection need to be prepared; the test strip is put into the test strip sorting equipment 2, and the test strip sorting equipment can orderly input the test strip 9 into the sample pretreatment equipment 1 through the test strip conveyor belt 21 according to a specified rule; the urine sample is loaded in the test tube 7, and the examiner places the test tube 7 in the test tube rack 71 of the sample preprocessing apparatus 1 and can start the examination.
Firstly, numbering test tubes 7 where samples are located sequentially through a touch screen 12, and inputting detection information, wherein the input detection information can establish and store files in a data processing terminal 6; after the data entry is completed, the detection work can be started; firstly, the test tube rack 71 is moved to a sampling position through the matching action of a transfer driving mechanism in the rotary sliding groove 15 and a transmission protrusion 72 at the bottom of the test tube rack 71; after reaching the preset position, stopping moving, and putting down the sampling needle 13 through the work of the sampling needle motor 16 so that the tip of the sampling needle 13 reaches the bottom of the test tube 7; then the urine sample in the test tube 7 is sucked into the sample pretreatment device 1 under the action of a peristaltic pump; after the sample enters the sample pretreatment device 1, the sample is respectively dripped into each detection area on the corresponding test strip 9 through a sample dripping pipe 171 arranged at the bottom of a sliding sample base 17; the excess urine sample is discharged into the waste liquid collector 18 through the dispensing dropper 171 and is discharged through the liquid feeding tube 19.
The test paper strip 9 with the urine sample is continuously transmitted to the urine sample detection device 3 through the conveyor belt and is respectively detected through the urine sample analyzer and the optical analyzer, the detection data is transmitted to the data processing terminal 6 in real time, and the record is stored according to the previously established archive; after all the tests are completed, the test process of the urine sample is finished once, and the test paper strip 9, the test tube 7 and other wastes can be conveyed into a post-test treatment system for treatment.
Example 2
The technical solution used in this embodiment is not different from the above embodiments, and the main difference is as follows: the present embodiment is intended to further explain and explain the post-detection processing system mentioned in the above embodiments.
As shown in fig. 3, a test tube robot 14 is provided in the sample pretreatment apparatus 1; the test tube mechanical arm 14 comprises a test tube clamping frame, and five clamping holes matched with the test tube rack 71 are formed in the test tube clamping frame; when the test tube clamping frame moves to a position where the test tube clamping frame is matched with the test tube in the test tube rack 71, the clamping holes can be contracted to clamp the test tube in the clamping holes; the test tube clamping frame is connected to the bottom of the test tube transfer device through a telescopic electric cylinder, and the test tube transfer device is arranged in a bottom sliding groove of a protruding part at the top of the processing bin; the test tube transfer device is provided with a transfer driving mechanism which comprises a transfer motor and a transfer wheel set and can be matched with the sliding groove to slide in the sliding groove; the front surface of the processing bin is provided with a groove matched with the test tube 9, and the bottom side in the groove is provided with a test tube conveyor belt for transmitting the test tube 9 to be processed to the post-detection processing system; after the test tube 9 finishes sampling and the urine sample inside is taken out, the test tube is clamped by the test tube clamping frame on the test tube mechanical arm 14 and is unloaded from the test tube rack 71; the test tube 9 is also brought into the sample preprocessing device 1 along with the inward movement of the test tube manipulator, and is placed in the test tube conveyer belt and sent into the post-inspection processing system for post-inspection processing.
The post-detection treatment system comprises a high-temperature ultraviolet treatment device 4, wherein the high-temperature ultraviolet treatment device 4 is respectively connected with a treatment bin of the sample pre-treatment device 1 through a liquid conveying pipeline 19 and connected with a urine sample detection device 3 and a test tube conveyor belt of the sample pre-treatment device through a closed conveyor belt 8, as shown in figure 2; the high-temperature ultraviolet treatment equipment 4 is also divided into three layers, namely a urine treatment cavity 41, a test strip treatment cavity 42 and a test tube treatment cavity 43 from low to high; respectively connected with the transfusion pipe 19, the closed conveyor belt 8 from the urine sample detection device 3 and the closed conveyor belt 8 from the sample processing device 1.
As shown in fig. 7, a urine pipe is provided in the lowermost urine treatment chamber 41, and an ultraviolet lamp 44 for emitting ultraviolet rays for sterilization is provided in the urine pipe; the outer layer of the urine pipeline is provided with a urine cavity heating layer 48 which can heat and sterilize the urine sample in the urine pipeline and can more effectively finish sterilization and disinfection work by matching with ultraviolet rays; the tail end of the urine pipeline is connected with a connecting pipeline 49, and the connecting pipeline 49 is connected to the high-temperature high-pressure steam bin 5, as shown in fig. 2; an electromagnetic valve is further arranged at the inlet of the connecting pipeline and used for controlling the opening and closing of the pipeline so as to ensure that the urine is sterilized and disinfected in the urine treatment cavity 41 for a long time.
The test strip processing cavity 42 and the test tube processing cavity 43 are both internally provided with an ultraviolet lamp tube 44 and a heater 45; the ultraviolet lamp tube is used for applying ultraviolet sterilization and disinfection to the cavity, and the heater 45 is used for heating, sterilizing and disinfecting the test strip 9 and the test tube 7 in the cavity; the test strip processing cavity 42 and the test tube processing cavity 43 are also internally provided with conveying belts 46 which are respectively matched and connected with the two closed conveying belts 8 and can receive the test strips 9 and the test tubes 7 transmitted by the closed conveying belts 8; outlets 47 are also arranged in the test strip processing cavity 42 and the test tube processing cavity 43 and are respectively connected with another two closed conveyor belts 8; two closed conveyer belts 8 of connecting the export are connected to abandonment test paper strip collecting region and abandonment test tube collecting region respectively for collect the test paper strip 9 and the test tube of having accomplished high temperature ultraviolet disinfection, with the follow-up processing of treating.
Further disinfection is required as the remaining liquid urine sample contains more contaminants and is more difficult to dispose of; the tail end of the connecting pipeline 49 is connected with a high-temperature high-pressure steam bin 5, so that the urine sample which is subjected to preliminary disinfection can be introduced into the high-temperature high-pressure steam bin 5 for further treatment; the bottom of the high-temperature high-pressure steam bin 5 is provided with a high-pressure steam generator which can output high-pressure high-temperature steam; the top of the urine collecting device is provided with a processing bin, urine to be processed can be temporarily stored in the processing bin, and high-temperature and high-pressure steam is introduced; the urine sample can be subjected to high-temperature and high-pressure steam treatment in the treatment bin, so that viruses, bacteria and the like in the urine sample can be killed; the treatment bin is provided with a liquid outlet, and the waste urine sample after treatment is basically harmless and can be directly discharged into a sewer pipeline; the waste gas generated in the process can be discharged into a subsequent gas treatment device through the exhaust port for further harmless treatment; or directly into the atmosphere.
In this embodiment, after completing a sample pretreatment in the sample pretreatment apparatus 1, the sample pretreatment apparatus 1 may be cleaned; the redundant urine samples are collected and discharged through the waste liquid collector 18, and at the moment, clear water, cleaning agent and the like in the liquid storage tank 11 can be pumped into the pipeline through the peristaltic pump, so that the pipeline which is in contact with the urine samples is cleaned in time, and the influence on the subsequent detection result is avoided; for the sampling needle 13, the cleaning liquid can be reversely discharged to the test tube 7 through the sampling needle 13 and then sucked back again to clean the test tube, and the test tube is cleaned preliminarily; the waste liquid generated by the self-cleaning process is also collected and discharged by the waste liquid collector 18.
After the self-cleaning is completed, the test tube 7 is driven by the test tube rack 71 to move forward continuously and reach the bottom of the test tube mechanical arm 14; the test tube mechanical arm 14 descends under the action of the servo electric cylinder, grabs the test tube 7 and lifts the test tube away from the test tube rack 71; the test tube rack 71 continues to move forwards and rotate, and can continue to receive new test tubes 7 when reaching the front half section of the rotating sliding groove 15; the test tube 7 to be processed can enter a transfer groove in the sample pretreatment device 1 under the driving of the test tube mechanical arm 14, is placed on a test tube conveying belt in the transfer groove, and is conveyed to the high-temperature ultraviolet treatment device 4.
After the test paper strip 9 completes all tests, the test paper strip can be conveyed into the high-temperature ultraviolet treatment equipment 4 through the closed conveyor belt 8 for post-test treatment; the high-temperature ultraviolet treatment equipment 4 comprises three layers and can respectively carry out high-temperature compound ultraviolet double sterilization and disinfection treatment on the liquid waste from the sample pretreatment equipment 1, the test tube and the test strip from the urine sample detection equipment 3; the test strip 9 and the test tube 7 after being processed are respectively transferred into a collection area through a conveyor belt to be collected for subsequent processing; the liquid waste is further transmitted into the high-temperature high-pressure steam bin 5 through a connecting pipeline 49 for high-temperature high-pressure steam treatment so as to further sterilize; after completion, the waste water is safely discharged to a sewer through the waste water pipe 51.
Example 3
The technical solution used in this embodiment is not substantially different from the above embodiments, and other main points are as follows: in the embodiment, the sample pretreatment device 1 and the high-temperature ultraviolet treatment device 4 are connected, and a test tube washing machine 81 is additionally arranged on the closed conveying belt 8 for conveying the test tubes 7; as shown in fig. 8.
The test tube washing machine 81 is arranged on a closed conveying belt 8 which connects the sample pretreatment device 1 and the high-temperature ultraviolet treatment device 4; the closed conveyor belt 8 is used for conveying test tubes 7 to be subjected to post-treatment, and a test tube washing machine 81 is arranged at the position and can be used for washing and disinfecting the test tubes 7 for one time before the test tubes 7 are subjected to high-temperature ultraviolet treatment; the test tube washing machine 81 is connected with the liquid storage tank 11 arranged at the top of the sample pretreatment device 1 through a liquid inlet pipeline, and clear water, detergent and the like required to be used for washing can be obtained from the liquid storage tank 11; the test tube washing machine 81 is sleeved outside the closed conveying belt 8, is internally provided with a multi-angle spray head, can carry out spray washing on the test tubes on the test tube conveying belt, and can completely wash out the residual urine which is not completely absorbed in the test tubes; the sewage after washing is merged into the transfusion pipeline 19 through the pipeline, enters the high-temperature ultraviolet treatment equipment 4 together with the residual urine sample, is subjected to post-detection treatment, and is safely discharged after the treatment is finished.

Claims (10)

1. The utility model provides a urine sample detects and examines after-treatment system, includes the urine detecting system who connects gradually and examines after-treatment system, its characterized in that: the urine detection system comprises sample pretreatment equipment, and test strip sorting equipment is arranged in a manner of being matched with the sample pretreatment equipment; the sample pretreatment equipment is connected with urine sample detection equipment, and the urine sample detection equipment comprises a urine sample analyzer and an optical analyzer; the post-examination treatment system comprises a liquid waste treatment system and a solid waste treatment system, wherein the liquid waste treatment system comprises a urine sample post-examination treatment device, and the solid waste treatment system comprises a test strip post-examination treatment device and a test strip post-examination treatment device; the post-treatment equipment for urine sample detection and the post-treatment equipment for test tube detection are both connected with the sample pretreatment equipment, and the post-treatment equipment for test strip detection is connected with the urine sample detection equipment.
2. The urine sample testing and post-test processing system according to claim 1, wherein: the sample pretreatment equipment comprises a sample table and a treatment bin, wherein the sample table is arranged in front of the treatment bin; a transfer groove is formed in the sample table and is a closed rotary groove in a shape like a Chinese character 'kou'; a transfer driving mechanism matched with the transfer groove is arranged in the sample table, and a sample transfer mechanism matched with the transfer groove is arranged on the processing bin; the sample transfer mechanism comprises a sampling needle, and the sampling needle is arranged on the sampler; the sampler is connected with a sample separating mechanism through a pipeline, and a test strip conveying mechanism is arranged in a manner of being matched with the sample separating mechanism; still be provided with the test tube arm on handling the storehouse, the test tube arm sets up on the test tube translator.
3. The urine sample detection and post-detection processing system according to claim 2, wherein: the sample separating mechanism comprises a sample separating dropper, and the sample separating dropper is connected with the sampler through a pipeline; a sample dividing cavity is arranged in the sample pretreatment equipment, a sliding sample dividing seat is arranged at the top of the sample dividing cavity, and the sample dividing dropper is arranged at the bottom of the sliding sample dividing seat; a telescopic table is arranged on the sliding sample separating seat, and a peristaltic pump is arranged in the sliding sample separating seat; the bottom of the sample separating cavity is provided with a test strip conveying mechanism, the test strip conveying mechanism comprises a test strip conveying belt, the starting end of the test strip conveying belt is connected with the test strip sorting equipment, and the terminal end of the test strip conveying belt is connected with the urine sample detection equipment.
4. The urine sample detection and post-detection processing system according to claim 3, wherein: the test tube mechanical arm comprises a telescopic electric cylinder, and a test tube clamping frame is arranged at the bottom end of the telescopic electric cylinder; the test tube mechanical arm is arranged at the bottom of the test tube transfer device, a transfer driving mechanism is arranged on the test tube transfer device, and the transfer driving mechanism comprises a transfer motor and a transfer wheel set; the sample pretreatment equipment is internally provided with a transfer groove matched with the transfer wheel set, a test tube conveyor belt is arranged below the inner side end of the transfer groove in a matched mode, and the end point end of the test tube conveyor belt is connected with the test tube post-detection treatment equipment.
5. The urine sample detection and post-detection processing system according to claim 4, wherein: the urine sample analyzer comprises a test strip positioning mechanism, and the test strip positioning mechanism is connected with the test strip conveying belt in a matching way; the test strip positioning mechanism comprises a positioning conveyor belt, and a plurality of test strip positioning points are arranged on the positioning conveyor belt; a fixed-track urine sample analysis probe is arranged in the urine sample analyzer, is arranged above the test strip positioning mechanism and is matched with the test strip positioning point; the optical analyzer is arranged at the tail end of the test strip positioning mechanism and comprises an optical analysis lens, and the optical analysis lens is matched with the test strip positioning point on the positioning conveyor belt.
6. The urine sample testing and post-test processing system according to claim 2, wherein: the post-processing equipment for the urine sample detection comprises high-temperature ultraviolet processing equipment, wherein a processing cavity is arranged in the high-temperature ultraviolet processing equipment, and an ultraviolet generator and a heater are arranged in the processing cavity; the sample pretreatment device is internally provided with a shunt pump, the shunt pump is arranged on a pipeline connecting the sampler and the sample separation mechanism, and the shunt pump is connected to the treatment cavity through a liquid discharge pipeline.
7. The urine sample detection and post-detection processing system according to claim 6, wherein: the post-processing equipment for the urine sample examination comprises a high-temperature high-pressure steam bin, wherein a high-pressure steam generator is arranged at the bottom of the high-temperature high-pressure steam bin, and the top of the high-pressure steam generator is connected with a processing bin; the treatment bin is provided with a liquid inlet, a liquid outlet and an air outlet, the liquid inlet is connected to the high-temperature ultraviolet treatment equipment through a liquid drainage pipeline, the liquid outlet is connected to a sewer pipeline, and the air outlet is connected to waste gas purification equipment.
8. The urine sample testing and post-test processing system according to claim 7, wherein: the tail end of a positioning conveyor belt in the urine sample detection equipment is connected with a test strip transfer conveyor belt, and the test strip transfer conveyor belt is connected with high-temperature ultraviolet treatment equipment; a test strip treatment cavity is arranged in the high-temperature ultraviolet treatment equipment, and an ultraviolet generator and a heater are arranged in the test strip treatment cavity; a leakage-proof closed pipeline is arranged between the urine sample detection equipment and the high-temperature ultraviolet treatment equipment, and the test strip transfer conveyor belt is arranged in the leakage-proof closed pipeline; the test strip treatment cavity in the high-temperature ultraviolet treatment equipment is connected to the waste test strip collection area through a waste conveyor belt.
9. The urine sample testing and post-test processing system according to claim 8, wherein: the test tube post-inspection processing equipment comprises a test tube washing machine, and the test tube washing machine is arranged on the test tube conveying belt; the test tube flushing machine is connected to high-temperature ultraviolet treatment equipment through a test tube conveyor belt, a test tube treatment cavity is arranged in the high-temperature ultraviolet treatment equipment, and an ultraviolet generator and a heater are arranged in the test tube treatment cavity; the test tube treatment cavity in the high-temperature ultraviolet treatment equipment is connected to the waste test tube collecting area through a waste conveying belt.
10. The urine sample testing and post-test processing system according to claim 1, wherein: an operation table is arranged on the sample preprocessing equipment and comprises a touch control screen; the touch control operation screen controls the urine sample detection equipment in a signal connection mode, and the urine sample detection equipment is connected with a data processing terminal in the signal connection mode.
CN202210274615.8A 2022-03-21 2022-03-21 Urine sample detects and examines after-treatment system Withdrawn CN114609401A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115184094A (en) * 2022-07-11 2022-10-14 苏州大学附属儿童医院 Urine container and matched exocrine urine examination analysis and processing system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115184094A (en) * 2022-07-11 2022-10-14 苏州大学附属儿童医院 Urine container and matched exocrine urine examination analysis and processing system

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Application publication date: 20220610