CN114601890A - Traditional Chinese medicine composition for children intestinal obstruction, patch and preparation method of patch - Google Patents
Traditional Chinese medicine composition for children intestinal obstruction, patch and preparation method of patch Download PDFInfo
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- CN114601890A CN114601890A CN202210197003.3A CN202210197003A CN114601890A CN 114601890 A CN114601890 A CN 114601890A CN 202210197003 A CN202210197003 A CN 202210197003A CN 114601890 A CN114601890 A CN 114601890A
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Abstract
The invention provides a traditional Chinese medicine composition for children intestinal obstruction, a patch and a preparation method of the patch, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 2-3 parts of cooked rhubarb or 2-3 parts of mirabilite; 2-3 parts of cortex magnoliae officinalis, or 2-3 parts of rhizoma atractylodis stir-fried with bran; 2-3 parts of bran-fried immature bitter orange or 1-3 parts of selfheal; 2-3 parts of vinegar-processed rhizoma cyperi or 2-3 parts of costustoot; 3-5 parts of white peony root or 2-4 parts of corydalis tuber; 3-4 parts of dandelion or 3-4 parts of Chinese violet; 3-5 parts of trichosanthes root or 3-4 parts of gynura bicolor seed; 2-5 parts of patrinia or 2-3 parts of sargentgloryvine stem; 3-4 parts of charred medicated leaven or 3-5 parts of fried radish seed; 2-3 parts of snakegourd peel or 2-3 parts of green tangerine peel, and the traditional Chinese medicine composition can be prepared into traditional Chinese medicine decoction pieces or granules for oral administration and can also be prepared into patches for external application. The beneficial effects of the invention are as follows: carbuncle and stagnation eliminating, qi circulation promoting, stagnation removing and pain relieving, intestinal obstruction can be effectively treated, and the patch can avoid conflict psychology of children in the treatment process.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for children intestinal obstruction, a patch and a preparation method of the patch.
Background
Intestinal obstruction is a general term for the passage of intestinal contents of any cause. It is one of the common surgical emergencies. Sometimes, acute intestinal obstruction is difficult to diagnose and the condition of the patient is fast to develop, so that the patient usually dies and the balance of water, electrolyte and acid-base is disordered. At present, the effective treatment means for the intestinal obstruction mainly adopts surgical operation.
In patent CN113197965A, an oral Chinese patent medicine for treating intestinal obstruction and a decocting method thereof are disclosed, wherein the intestinal obstruction can be effectively treated by decocting a Chinese medicinal mixture consisting of radix asparagi, rehmannia root, ginseng, astragalus root, plantain herb, rhubarb, immature bitter orange and dried orange peel into decoction for administration.
For the treatment of children intestinal obstruction, the comfort of the treatment of children is reduced by performing operations and directly taking the traditional Chinese medicine preparation orally, and meanwhile, the children can easily delay the treatment by conflicting psychology for taking the traditional Chinese medicine preparation, so that a method for conveniently and effectively treating the intestinal obstruction of the children is needed.
Disclosure of Invention
In order to solve the technical problems, the invention discloses a traditional Chinese medicine composition, a patch and a preparation method of the patch for children ileus, wherein the traditional Chinese medicine composition, the patch and the preparation method of the patch can be used for quickly and effectively treating ileus and preventing children from resisting treatment, and the technical scheme of the invention is implemented as follows:
a traditional Chinese medicine composition for treating children intestinal obstruction comprises the following raw materials in parts by weight: 2-3 parts of cooked rhubarb or 2-3 parts of mirabilite; 2-3 parts of cortex magnoliae officinalis, or 2-3 parts of rhizoma atractylodis stir-fried with bran; 2-3 parts of bran-fried immature bitter orange or 1-3 parts of selfheal; 2-3 parts of vinegar-processed rhizoma cyperi or 2-3 parts of costustoot; 3-5 parts of white peony root or 2-4 parts of corydalis tuber; 3-4 parts of dandelion or 3-4 parts of Chinese violet; 3-5 parts of trichosanthes root or 3-4 parts of gynura bicolor seed; 2-5 parts of patrinia or 2-3 parts of sargentgloryvine stem; 3-4 parts of charred medicated leaven or 3-5 parts of fried radish seed; 2-3 parts of snakegourd peel or 2-3 parts of green tangerine peel.
The cooked rhubarb in the invention has the effects of purging heat, promoting bowel movement, cooling blood, removing toxicity, removing blood stasis and dredging channels; natrii sulfas has effects of relaxing bowels with purgative, moistening dryness, softening hard masses, clearing pathogenic fire and relieving swelling; the cortex Magnolia officinalis has effects in promoting qi circulation, eliminating dampness, resolving food stagnation, and relieving flatulence; rhizoma Atractylodis parched with bran has effects of eliminating dampness, invigorating spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight; the fructus Aurantii Immaturus parched with bran has effects of resolving qi stagnation, eliminating phlegm and relieving oppression; spica Prunellae has effects of removing liver heat, purging pathogenic fire, improving eyesight, resolving hard mass, and relieving swelling; vinegar rhizoma Cyperi has effects of dispersing stagnated liver qi for relieving qi stagnation, regulating qi-flowing for relieving epigastric distention, regulating menstruation and relieving pain; radix aucklandiae has effects of activating qi-flowing, relieving pain, invigorating spleen and resolving food stagnation; radix Paeoniae alba has effects of nourishing blood, regulating menstruation, astringing yin, arresting sweating, softening liver, relieving pain, and suppressing liver yang; rhizoma corydalis has effects of promoting blood circulation, activating qi-flowing, and relieving pain; the herba Taraxaci has effects of clearing away heat and toxic materials, relieving swelling, resolving hard mass, inducing diuresis and treating stranguria; the herba Violae has effects of clearing pathogenic fire, removing toxic substances, eliminating phlegm, and resolving masses; radix Trichosanthis has effects of clearing heat, promoting fluid production, relieving swelling and expelling pus; the gynura bicolor has the effects of clearing heat and removing toxicity, and reducing swelling and dissipating stagnation; herba Patriniae has effects of clearing away heat and toxic materials, eliminating carbuncle, expelling pus, removing blood stasis, and relieving pain; caulis Sargentodoxae has effects of clearing away heat and toxic materials, promoting blood circulation, dispelling pathogenic wind, and relieving pain; the charred Massa Medicata Fermentata has effects of invigorating spleen and stomach, resolving food stagnation, and regulating middle warmer; the parched Raphani semen has effects of resolving food stagnation, relieving flatulence, descending qi and eliminating phlegm; the pericarpium Trichosanthis has effects of clearing heat, eliminating phlegm, relieving chest stuffiness, resolving hard mass, and moisturizing intestine; pericarpium Citri Reticulatae viride has effects of dispersing stagnated liver qi, relieving qi stagnation, and resolving food stagnation.
The traditional Chinese medicine composition for treating children intestinal obstruction can be prepared into decoction pieces or granules for oral administration and granules for grinding for external application.
A patch for children intestinal obstruction comprises an anti-seepage plaster cloth, a pressure-sensitive adhesive layer and a medicine storage layer, wherein the pressure-sensitive adhesive layer and the medicine storage layer are arranged on the same side of the anti-seepage plaster cloth, and the medicine storage layer comprises the traditional Chinese medicine composition for children intestinal obstruction.
The preparation method of the patch for children intestinal obstruction specifically comprises the following steps: s1: grinding into powder using a traditional Chinese medicine composition for treating children's intestinal obstruction of claim 1; s2: preparing a cake-shaped, paste-shaped or pasty medicine-containing mixture by using pharmaceutically acceptable auxiliary materials; s3: and filling the medicine-containing mixture obtained in the step S2 into the anti-seepage plaster cloth containing the pressure-sensitive adhesive layer.
The preparation method of the patch for children intestinal obstruction is characterized by comprising the following steps: in S2, the pharmaceutically acceptable excipients include: yellow wine and glycerol.
By implementing the technical scheme of the invention, the technical problems that the comfort of children is reduced and the conflict psychology that children resist treatment is increased in the treatment of children intestinal obstruction in the prior art can be solved; by adopting the technical scheme of the invention, the traditional Chinese medicine composition is prepared into decoction pieces, granules or patches, so that the technical effect of quickly and effectively treating intestinal obstruction and effectively avoiding the psychological conflict generated by children in the treatment process by adopting the patches and other modes can be realized.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only one embodiment of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
In which like parts are designated by like reference numerals. It should be noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, and the terms "bottom" and "top," "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.
FIG. 1 is a schematic diagram of a patch for pediatric ileus;
fig. 2 is a schematic diagram of the patch preparation process for children intestinal obstruction.
In the above drawings, the reference numerals denote:
1 seepage-proofing plaster cloth
2 pressure-sensitive adhesive layer
3 medicine reservoir layer
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
In a specific embodiment 1, a traditional Chinese medicine composition for treating children intestinal obstruction comprises the following raw materials in parts by weight: 2-3 parts of cooked rhubarb or 2-3 parts of mirabilite; 2-3 parts of cortex magnoliae officinalis, or 2-3 parts of rhizoma atractylodis stir-fried with bran; 2-3 parts of bran-fried immature bitter orange or 1-3 parts of selfheal; 2-3 parts of vinegar-processed rhizoma cyperi or 2-3 parts of costustoot; 3-5 parts of white peony root or 2-4 parts of corydalis tuber; 3-4 parts of dandelion or 3-4 parts of Chinese violet; 3-5 parts of trichosanthes root or 3-4 parts of gynura bicolor seed; 2-5 parts of patrinia or 2-3 parts of sargentgloryvine stem; 3-4 parts of charred medicated leaven or 3-5 parts of fried radish seed; 2-3 parts of snakegourd peel or 2-3 parts of green tangerine peel. The Chinese medicinal composition is decocted with water for twice a day, and the dosage for oral administration is specifically adjusted according to patients of different age groups, and the dosage can refer to: 1-3 years old: 30-50 ml each time; 4-6 years old: 60-80 ml each time; 7-9 years old: 90-120 ml each time; age 10 to 12 years: 150 ml each time; over 13 years old: 200 ml each time. The traditional Chinese medicine composition can be directly decocted with water for oral administration, can be prepared into granules, is brewed with boiled water for twice daily oral administration, and can be adjusted according to different age groups of patients, and the dosage can refer to: 1-3 years old: 30-50 ml each time; 4-6 years old: 60-80 ml each time; 7-9 years old: 90-120 ml each time; age 10 to 12 years: 150 ml each time; over 13 years old: 200 ml each time.
Example 2
Patient 1, complaint symptoms: abdominal pain, abdominal distension, nausea, 2 days after the acute suppurative appendicitis operation; physical examination of body signs: red tongue with yellow, greasy and thick coating, thready pulse, and tenderness when pressing abdomen, abdominal hardness and abdominal distension; b ultrasonic and abdominal plain examination: indicating ileus. And (3) Western diagnosis: ileus; traditional Chinese medicine diagnosis: and (4) accumulation of symptoms.
Administration: 2 parts of cooked rhubarb, 2 parts of mirabilite, 2 parts of cortex magnoliae officinalis, 2 parts of bran-fried immature bitter orange, 2 parts of vinegar rhizoma cyperi, 3 parts of radix paeoniae alba, 3 parts of dandelion, 4 parts of trichosanthes root, 3 parts of herba patriniae, 3 parts of charred medicated leaven and 3 parts of pericarpium trichosanthis.
The use method comprises the following steps: grinding the above Chinese medicinal materials into powder, concocting with yellow wine to obtain cake, and applying to Tianshu acupoint and Dazhuang acupoint for 2 times a day for 1 hr each time.
The curative effect is as follows: the patients are retested after taking the medicine for 2 days, the symptoms of abdominal pain, abdominal distension, nausea and the like of the patient 1 are obviously improved, and B ultrasonic examination and abdominal plain film examination are as follows: prompting the intestinal obstruction to be improved; the patient 1 has no symptoms such as abdominal pain, abdominal distension and nausea after the treatment of the compound preparation for 5 days, and the B ultrasonic examination and the abdominal plain film examination: no intestinal obstruction was noted.
Example 3
Patient 2, complaint symptoms: 4 days after acute abdominal trauma small intestine section excision, abdominal pain, abdominal distension and nausea; physical examination of body signs: red tongue with white, greasy and thick coating, thready pulse, tenderness when pressing abdominal hardness and abdominal distension; b ultrasonic and abdominal plain examination: indicating ileus. And (3) Western diagnosis: ileus; traditional Chinese medicine diagnosis: and (4) accumulation of symptoms.
Administration: 3 parts of cooked rhubarb, 2 parts of mirabilite, 3 parts of cortex magnoliae officinalis, 3 parts of bran-fried immature bitter orange, 3 parts of vinegar-fried rhizoma cyperi, 3 parts of elecampane, 4 parts of radix paeoniae alba, 4 parts of rhizoma corydalis, 4 parts of dandelion, 4 parts of Chinese violet, 4 parts of radix trichosanthis, 3 parts of herba patriniae, 3 parts of sargentgloryvine stem, 4 parts of charred medicated leaven and 3 parts of pericarpium trichosanthis.
The use method comprises the following steps: (1) grinding the above Chinese medicinal materials into powder, concocting with yellow wine to obtain cake, and applying to Tianshu acupoint and Dazhuang acupoint for 2 times a day for 1 hr each time. (2) Preparing the traditional Chinese medicines into granules: the medicine is taken with boiled water 2 times a day, 100 ml each time.
The curative effect is as follows: the patients are retested after taking the medicine for 2 days, the symptoms of abdominal pain, abdominal distension, nausea and the like are improved, B-mode ultrasonography and abdominal plain film examination are carried out: prompting the intestinal obstruction to be improved; the patients are retested after taking the medicine for 5 days, the patients have no symptoms such as abdominal pain, abdominal distension, nausea and the like, B-mode ultrasonography and abdominal plain film examination: no intestinal obstruction was noted.
Example 4
The method comprises the following steps of (1) administration: 2 parts of cooked rhubarb, 2 parts of officinal magnolia bark, 2 parts of rhizoma atractylodis fried with bran, 2 parts of immature bitter orange fried with bran, 2 parts of rhizoma cyperi with vinegar, 2 parts of elecampane, 2 parts of corydalis tuber, 3 parts of dandelion, 3 parts of trichosanthes root, 2 parts of dahurian patrinia herb, 3 parts of medicated leaven and 2 parts of snakegourd peel.
The use method comprises the following steps: grinding the above Chinese medicinal materials into powder, concocting with yellow wine to obtain cake, and applying to Tianshu acupoint and Dazhuang acupoint for 2 times a day for 1 hr each time.
The curative effect is as follows: the patients are subjected to a re-diagnosis after 1 day of administration, the symptoms of abdominal pain, abdominal distension, nausea and the like of the patients are improved, B-mode ultrasonography and abdominal plain film examination: prompting the intestinal obstruction to be improved; the patient is retested after taking the medicine for 3 days, the symptoms such as abdominal pain, abdominal distension, nausea and the like of the patient are obviously improved, and B ultrasonic examination and abdominal plain examination are as follows: prompting that intestinal obstruction is obviously improved; the patient 3 has no symptoms such as abdominal pain, abdominal distension and nausea after the treatment of the compound preparation for 5 days, and the B ultrasonic examination and the abdominal plain film examination: no intestinal obstruction was noted.
Example 5
Patient 4, complaint symptoms: abdominal pain, abdominal distension, nausea and vomiting after the abdominal exploration for adhesive ileus 5 days after bone marrow transplantation for aplastic anemia; physical examination of body signs: red tongue with yellow, greasy and thick coating and light finger print, and tenderness due to abdominal hardness and abdominal distension during pressing; b ultrasonic and abdominal plain examination: indicating ileus. And (3) Western diagnosis: ileus; traditional Chinese medicine diagnosis: and (4) accumulation of symptoms.
Administration: 2 parts of mirabilite, 2 parts of cortex magnoliae officinalis, 2 parts of rhizoma atractylodis stir-fried with bran, 2 parts of prunella vulgaris, 2 parts of elecampane, 2 parts of rhizoma corydalis, 3 parts of Chinese violet, 3 parts of gynura bicolor seed, 2 parts of sargentgloryvine stem, 3 parts of fried radish seed and 2 parts of pericarpium citri reticulatae viride.
The use method comprises the following steps: grinding the above Chinese medicinal materials into powder, concocting with yellow wine to obtain cake, and applying to Tianshu acupoint and Dazhuang acupoint for 2 times a day for 1 hr each time.
The curative effect is as follows: the patients are retested after taking the medicine for 2 days, the symptoms of 4 patients such as abdominal pain, abdominal distension, nausea and the like are obviously improved, B ultrasonic examination and abdominal plain film examination are as follows: prompting the intestinal obstruction to be improved; the patients are re-diagnosed after 5 days of medication, the patients 4 have no symptoms such as abdominal pain, abdominal distension and nausea, B-ultrasonic examination and abdominal plain film examination: no intestinal obstruction was noted.
Example 6
Patient 5, complaint symptoms: acute suppurative appendicitis with abdominal pain, abdominal distention, nausea after 2 days of perforation; physical examination of body signs: red tongue with yellow, greasy and thick coating, thready pulse, and tenderness when pressing abdomen, abdominal hardness and abdominal distension; b ultrasonic and abdominal plain examination: indicating ileus. And (3) Western diagnosis: ileus; traditional Chinese medicine diagnosis: and (4) accumulation of symptoms.
Administration: 2 parts of cooked rhubarb, 2 parts of mirabilite, 2 parts of cortex magnoliae officinalis, 2 parts of bran-fried immature bitter orange, 2 parts of vinegar rhizoma cyperi, 3 parts of radix paeoniae alba, 3 parts of dandelion, 3 parts of trichosanthes root, 2 parts of herba patriniae, 3 parts of charred medicated leaven and 2 parts of pericarpium trichosanthis.
The use method comprises the following steps: grinding the above Chinese medicinal materials into powder, concocting with yellow wine to obtain cake, and applying to Tianshu acupoint and Dazhuang acupoint for 2 times a day for 1 hr each time.
The curative effect is as follows: the compound treatment is carried out after 2 days of administration, the symptoms of abdominal pain, abdominal distension, nausea and the like of a patient 5 are obviously improved, and B ultrasonic examination and abdominal plain film examination are as follows: prompting the intestinal obstruction to be improved; the patients are subjected to the double-diagnosis after 5 days of administration, and 5 patients have no symptoms such as abdominal pain, abdominal distension, nausea and the like, and are examined by B ultrasonic and abdominal plain films: no intestinal obstruction was noted.
Example 7
A patch for children intestinal obstruction is shown in figure 1 and comprises an anti-seepage plaster cloth 1, a pressure-sensitive adhesive layer 2 and a medicine storage layer 3, wherein the pressure-sensitive adhesive layer 2 and the medicine storage layer 3 are arranged on the same side of the anti-seepage plaster cloth 1, the anti-seepage plaster cloth 1 prevents medicines in the medicine storage layer 3 from leaking and further influences the medicine effect, the pressure-sensitive adhesive layer 2 prevents the patch from falling off, and the materials of the anti-seepage plaster cloth 1 and the pressure-sensitive adhesive layer 2 can be selected by the existing common prior art as long as the related functions are realized. The drug reservoir layer 1 comprises the traditional Chinese medicine composition for treating children intestinal obstruction in example 1, and the traditional Chinese medicine composition in example 1 is ground into powder and then treated to form the drug reservoir layer 3. The patch can be applied to Tianshu acupoint and Dazhuang acupoint according to different symptoms of patients, 2 times per day, and 1 hour each time for effectively treating intestinal obstruction. In addition, the shape of the patch can adopt different designs, and the shape of a small animal or a small plant or the design of different colors can effectively avoid the conflict psychology of children in the treatment process and increase the child interest, thereby being convenient for treating diseases.
Example 8
A preparation method of a patch for children intestinal obstruction is shown in figure 2, and specifically comprises the following steps: s1: grinding the traditional Chinese medicine composition for treating children intestinal obstruction, which is described in example 1, into powder; s2: mixing pharmaceutically acceptable adjuvants with the obtained Chinese medicinal composition to obtain cake, paste or pasty mixture containing medicine, wherein the pharmaceutically acceptable adjuvants include yellow wine or glycerol; s3: the patch for childhood intestinal obstruction of example 7 was obtained by filling the drug-containing mixture obtained in S2 into the patch for prevention of leakage plaster 1 containing the pressure-sensitive adhesive layer 2 to form the reservoir layer 3.
It should be understood that the above-described embodiments are merely exemplary of the present invention, and are not intended to limit the present invention, and that any modification, equivalent replacement, or improvement made without departing from the spirit and principle of the present invention shall fall within the protection scope of the present invention.
Claims (4)
1. A traditional Chinese medicine composition for treating children intestinal obstruction is characterized in that: comprises the following raw materials in parts by weight: 2-3 parts of cooked rhubarb or 2-3 parts of mirabilite; 2-3 parts of cortex magnoliae officinalis, or 2-3 parts of rhizoma atractylodis stir-fried with bran; 2-3 parts of bran-fried immature bitter orange or 1-3 parts of selfheal; 2-3 parts of vinegar-processed rhizoma cyperi or 2-3 parts of costustoot; 3-5 parts of white peony root or 2-4 parts of corydalis tuber; 3-4 parts of dandelion or 3-4 parts of Chinese violet; 3-5 parts of trichosanthes root or 3-4 parts of gynura bicolor seed; 2-5 parts of patrinia or 2-3 parts of sargentgloryvine stem; 3-4 parts of charred medicated leaven or 3-5 parts of fried radish seed; 2-3 parts of snakegourd peel or 2-3 parts of green tangerine peel.
2. The utility model provides a patch for children's ileus, includes prevention of seepage cream medicated cloth, pressure-sensitive adhesive layer and medicine storehouse layer, wherein pressure-sensitive adhesive layer with the medicine storehouse layer sets up the homonymy of prevention of seepage cream medicated cloth, its characterized in that: the drug reservoir layer comprises the traditional Chinese medicine composition for treating children intestinal obstruction in claim 1.
3. A method for preparing a patch for ileus of children according to claim 2, which comprises the following steps: s1: grinding into powder using a traditional Chinese medicine composition for treating children's intestinal obstruction of claim 1; s2: preparing a cake-shaped, paste-shaped or pasty medicine-containing mixture by using pharmaceutically acceptable auxiliary materials; s3: and filling the medicine-containing mixture obtained in the step S2 into the anti-seepage plaster cloth containing the pressure-sensitive adhesive layer.
4. A method of preparing a patch for ileus in children according to claim 3, characterized in that: in S2, the pharmaceutically acceptable excipients include: yellow wine and glycerol.
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