CN114601032A - Additive with function of gastrointestinal anti-stress - Google Patents
Additive with function of gastrointestinal anti-stress Download PDFInfo
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- CN114601032A CN114601032A CN202210362800.2A CN202210362800A CN114601032A CN 114601032 A CN114601032 A CN 114601032A CN 202210362800 A CN202210362800 A CN 202210362800A CN 114601032 A CN114601032 A CN 114601032A
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/22—Compounds of alkali metals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/20—Animal feeding-stuffs from material of animal origin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Birds (AREA)
- Fodder In General (AREA)
Abstract
The invention discloses an additive with intestine and stomach stress prevention, which comprises the following raw materials in parts by weight: 2-8 parts of sodium bicarbonate, 0.55-0.65 part of bacitracin zinc, 4-9 parts of glucose, 0.55-0.65 part of fumaric acid, 0.5-1.5 parts of chromium yeast, 1-7 parts of whole cottonseed, 10-20 parts of rumen bypass fat, 1-5 parts of centipede, 1-5 parts of Chinese pine, 2-5 parts of cinnabar, 2-7 parts of daub, 8-25 parts of walnut, 2-4 parts of edible tulip, 3-6 parts of dried ginger, 2-6 parts of angelica, 2-4 parts of water chestnut and 1-3 parts of phoenix-tail fern. The invention has obvious improvement on blood pH and alkali storage, high temperature resistance effect, enzyme activity increase, feed intake increase, weight increment and the like, and has obvious reduction and reduction on gastrointestinal diarrhea rate, toxic metabolite reduction rate and the like, so that the gastrointestinal anti-stress effect in pet feeding is better, the effect is more comprehensive, and the production requirement of the existing pet feeding is greatly met.
Description
Technical Field
The invention relates to the technical field of additives, in particular to an additive with gastrointestinal anti-stress function.
Background
Stress is the sum of nonspecific responses of the body to various external or internal extraordinary stimuli, and is the response of an animal to stimuli or challenges inside and outside the body. The low immunity is a main factor causing stress, the stress harm is many, such as the reduction of production performance, the low immunity, the low fecundity, the reduction of animal product quality, the increase of demand and the lack of nutrition, and the most serious sudden death caused by stress brings great economic loss to farmers, so that the attention of the farmers is paid to how to resist the stress and prevent the sudden death.
The anti-stress agent is a feed additive capable of relieving and preventing stress syndrome caused by a stress source. At present, the anti-stress additives commonly used in livestock and poultry production comprise minerals, fats, sugars, vitamins and organic acids, antibiotics and the like. For example, CN106135639B, which is a prior art, discloses a Chinese herbal medicine feed additive for resisting swine heat stress, which contains active ingredients, wherein the active ingredients are prepared from raw gardenia, scutellaria, pueraria, isatis leaf, gypsum, anemarrhena, cortex lycii radicis, dandelion, bunge corydalis herb and yerbadetajo herb. The Chinese herbal medicine additive disclosed by the invention gives full play to the compatibility advantages of Chinese herbal medicines, can obviously increase the average daily gain and daily feed intake, obviously reduces the feed conversion ratio, and obviously improves the production performance of pigs. However, in the prior art, the gastrointestinal anti-stress effect in feeding some cats and dogs is not good, the effect is not comprehensive, and when some stress reactions occur, gastrointestinal diseases such as diarrhea are easy to occur, so that the production requirements of feeding pets such as the existing cats and dogs are difficult to meet; therefore, the invention provides an additive with gastrointestinal anti-stress function.
Disclosure of Invention
Based on the technical problems in the background art, the invention provides an additive with gastrointestinal anti-stress function.
The invention provides an additive with intestine and stomach stress prevention, which comprises the following raw materials in parts by weight:
2-8 parts of sodium bicarbonate, 0.55-0.65 part of bacitracin zinc, 4-9 parts of glucose, 0.55-0.65 part of fumaric acid, 0.5-1.5 parts of chromium yeast, 1-7 parts of whole cottonseed, 10-20 parts of rumen bypass fat, 1-5 parts of centipede, 1-5 parts of Chinese pine, 2-5 parts of cinnabar, 2-7 parts of daub, 8-25 parts of walnut, 2-4 parts of edible tulip, 3-6 parts of dried ginger, 2-6 parts of angelica, 2-4 parts of water chestnut and 1-3 parts of phoenix-tail fern;
the additive with intestine and stomach stress prevention can improve the heat stress symptom of the pet, simultaneously can obviously increase the daily feed intake and average daily gain of the pet, can promote growth and enhance resistance;
the preparation method of the additive with gastrointestinal anti-stress function comprises the following steps:
(1) sterilizing Scolopendra, herba Lycopodii, Cinnabaris, semen Setariae, semen Juglandis, Pseudobulbus Cremastrae seu pleiones, Zingiberis rhizoma, radix Angelicae sinensis, corm Eleocharitis, and herba Pteridis Multifidae;
(2) then, carrying out preliminary milling and crushing on centipede, Chinese pine, cinnabar, african amomum fruit, walnut, edible tulip, dried ginger, Chinese angelica, water chestnut and Chinese brake herb in each solid raw material, and then mixing and stirring each preliminary crushed raw material for 20-45 minutes;
(3) then adding the rest sodium bicarbonate, bacitracin zinc, glucose, fumaric acid, yeast chromium, whole cottonseed and rumen bypass fat into the mixture, and adding purified water to mix for 10-25 minutes until the mixture is uniformly mixed into paste;
(4) heating and drying the stirred pasty raw material at the temperature of 36-38 ℃ for 10-15 minutes;
(5) and crushing the dried mixed raw materials until the mixed raw materials pass through a 45-60-mesh sieve, weighing the mixed raw material powder, and subpackaging to obtain the finished product of the gastrointestinal anti-stress additive.
As a further preference, the weight ratio of the Chinese pine to the centipede is 1-1.5: 2-3.5.
As a further preference, the weight ratio of the whole cottonseed to the rumen bypass fat is 4.5-5.2: 1.3-1.5.
The composition further preferably comprises the following raw materials in parts by weight: 2-6 parts of sodium bicarbonate, 0.55-0.6 part of bacitracin zinc, 4-8 parts of glucose, 0.55-0.65 part of fumaric acid, 0.5-1.5 parts of chromium yeast, 1-7 parts of whole cottonseed, 10-18 parts of rumen bypass fat, 1-5 parts of centipede, 1-4 parts of Chinese pine, 2-5 parts of cinnabar, 2-5 parts of daub, 8-23 parts of walnut, 2-4 parts of edible tulip, 3-6 parts of dried ginger, 2-5 parts of angelica, 2-4 parts of water chestnut and 1-3 parts of phoenix-tail fern.
The composition further preferably comprises the following raw materials in parts by weight: 4 parts of sodium bicarbonate, 0.55 part of bacitracin zinc, 5 parts of glucose, 0.65 part of fumaric acid, 1.5 parts of yeast chromium, 5 parts of whole cottonseed, 18 parts of rumen bypass fat, 2 parts of centipede, 3 parts of Chinese pine, 5 parts of cinnabar, 2 parts of daub, 20 parts of walnut, 4 parts of edible tulip, 5 parts of dried ginger, 2 parts of angelica, 2 parts of water chestnut and 3 parts of Chinese brake herb.
Preferably, in the step (4), the stirred paste raw material is heated and dried at a temperature of 36-37.5 ℃ for 12-15 minutes.
More preferably, in the step (4), the stirred pasty raw material is heated and dried, wherein the drying temperature is 37.5 ℃, and the drying time is 12 minutes.
Preferably, in the step (5), the dried mixed raw materials are crushed again until the mixed raw materials pass through a 55-mesh sieve, and then the mixed raw material powder is weighed and subpackaged to obtain the finished product of the gastrointestinal anti-stress additive.
Preferably, the yeast chromium is added in an amount of 0.4 mg/kg per day in the feed, and can be supplemented with organic chromium, thereby improving the production performance and enhancing the immunity.
The additive with the function of preventing the gastrointestinal stress, provided by the invention, analyzes and demonstrates the medicine properties and pharmacological effects of the raw materials as follows:
sodium bicarbonate, which is an electrolyte additive and an acid-base modifier; the buffer capacity of the organism is ensured to be strong, and the pH value and the alkali storage of blood are improved, so that the endocrine system can work and operate normally when suffering from strong stress; can relieve heat stress, and can improve the milk fat rate and total solid content of cat and dog by adding daily sodium bicarbonate into daily ration of cat and dog, so as to improve milk yield.
The bacitracin zinc has a good application effect on relieving the heat stress of the pet; the action mechanism is that the composition can inhibit the formation of pathogenic bacteria cell walls, influence the synthesis of pathogenic bacteria protein, influence the functions of certain cell membranes and finally inhibit or kill pathogenic bacteria; can improve the structure of the intestinal wall, thin the intestinal wall and increase the absorption of nutrients; can also increase the activity of some enzymes and regulate the metabolism of the organism; the high temperature resistant effect is obvious; zinc bacitracin allows pets to use most of the energy for weight gain with reduced thermogenesis in the body.
Glucose can relieve the influence of heat stress on blood properties, improve heat dissipation, reduce toxic metabolites in blood, reduce death rate, and increase weight.
Fumaric acid, an acidifier, can regulate acid-base balance, and prevent blood pH increase caused by heat stress; fumaric acid has tranquilizing effect, and can inhibit central nerve, reduce body activity, and reduce heat production.
Chromium can influence the reaction of animals to stress by changing the secretion of cortical hormone and enhancing the utilization of glucose, has the function of slowing down stress, reduces the level of serum cortisol, improves daily gain and feed conversion rate, enhances the immune function and reduces the morbidity; the common organic chromium is chromium nicotinate, chromium picolinate, chromium yeast, chromium amino acid, chromium protein and the like, wherein the chromium picolinate and the chromium yeast have good use effect.
Whole cottonseed and rumen bypass fat can supplement energy loss caused by anorexia during heat stress; the influence of heat stress on the cats and dogs can be relieved by adding 10.3% of whole cotton seeds or 2.6% of rumen bypass fat or adding 5.2% of whole cotton seeds and 1.3% of rumen bypass fat into the daily ration of the cats and dogs, so that the dry matter feed intake and the milk yield are increased;
scolopendra and herba Lycopodii can resist convulsion; cinnabar, fructus Formosanae, etc. have sedative and hypnotic effects; herba plantaginis has effects in clearing away heat, relieving summer-heat, and cooling.
Walnut: has effects of benefiting qi, nourishing blood, warming lung, moisturizing intestine, and treating hernia pain.
And (3) edible tulip: has blood circulation promoting effect, contains abundant proteins, and has effects of promoting growth and enhancing resistance.
Dried ginger: has effects in warming spleen and stomach, dispelling cold, restoring yang, dredging collaterals, warming lung, and eliminating phlegm; especially has unique effects of warming stomach and dredging collaterals.
Chinese angelica root: pungent, warm and nontoxic, and has effects of invigorating qi and blood, moistening dryness, smoothing intestine, and improving immunity.
Water chestnut: has the effects of promoting fluid production, clearing heat, eliminating phlegm, clearing stomach fire, and purging kidney heat.
Pteris multifida: the Chinese medicinal composition has slightly bitter taste, enters liver, kidney and large intestine channels, has the effects of clearing heat, promoting diuresis, relieving swelling, detoxifying and the like, is used for treating dysentery and enteritis, is beneficial to reducing gastrointestinal diseases, and further has the effect of preventing gastrointestinal stress.
In conclusion, the beneficial effects of the invention are as follows:
1) compared with the conventional additive, the additive with the function of gastrointestinal anti-stress provided by the invention has the advantages that the blood pH and alkali storage, high temperature resistance, enzyme activity increase, feed intake increase, weight increment and the like are obviously improved, and meanwhile, the gastrointestinal diarrhea rate, the toxic metabolite reduction rate and the like are obviously reduced and reduced, so that the effect is more comprehensive.
2) The additive with the intestine and stomach anti-stress function provided by the invention has a better effect on intestine and stomach anti-stress function particularly in the feeding of some cats and dogs, and the addition of the sodium bicarbonate is helpful for ensuring that an organism has strong buffering power and improving the pH value and alkali storage of blood, so that an endocrine system can work and operate normally when suffering from strong stress, the heat stress can be relieved, and the daily sodium bicarbonate is added into daily ration of the cats and dogs, so that the milk fat rate and the total solid content of the cats and dogs can be improved, and the milk yield is improved; by adding bacitracin zinc, the pet can use most of energy for weight gain, reduce heat generation in vivo, increase enzyme activity, regulate organism metabolism and have more obvious high temperature resistance effect; by adding glucose, the influence of heat stress on blood properties can be relieved, heat dissipation is improved, toxic metabolites in blood can be reduced, the death rate is reduced, and weight gain is improved; by adding fumaric acid, acid-base balance can be adjusted, blood pH increase caused by heat stress can be prevented, and the composition has tranquilizing effect and can reduce body activity, thereby reducing heat production; by adding the yeast chromium, the daily gain and the feed conversion rate are improved, the immune function is enhanced, and the morbidity is reduced; by adding whole cottonseed and rumen bypass fat, energy loss caused by anorexia can be supplemented during heat stress, and influence of heat stress on cat and dog can be relieved.
3) In addition, the centipede and the rhizoma pinelliae have the function of resisting convulsion; cinnabar, fructus intolerance and the like have the functions of calming and hypnosis; herba plantaginis has effects in clearing away heat, relieving summer-heat, and cooling; the edible tulip can promote growth and enhance resistance; the water chestnut has the effects of clearing stomach fire and purging kidney heat; the phoenix-tail fern is beneficial to reducing the occurrence of gastrointestinal diseases, and further has the effect of preventing gastrointestinal stress; finally, the intestine and stomach anti-stress effect in pet feeding is better, the effect is more comprehensive, and the production requirement of the existing pet feeding is greatly met.
Detailed Description
The present invention will be further illustrated with reference to the following specific examples.
Example 1
The invention provides an additive with gastrointestinal anti-stress function, which comprises the following raw materials in parts by weight:
2-8 parts of sodium bicarbonate, 0.55-0.65 part of bacitracin zinc, 4-9 parts of glucose, 0.55-0.65 part of fumaric acid, 0.5-1.5 parts of chromium yeast, 1-7 parts of whole cottonseed, 10-20 parts of rumen bypass fat, 1-5 parts of centipede, 1-5 parts of Chinese pine, 2-5 parts of cinnabar, 2-7 parts of daub, 8-25 parts of walnut, 2-4 parts of edible tulip, 3-6 parts of dried ginger, 2-6 parts of angelica, 2-4 parts of water chestnut and 1-3 parts of phoenix-tail fern;
the additive with intestine and stomach stress prevention can improve the heat stress symptom of the pet, simultaneously can obviously increase the daily feed intake and average daily gain of the pet, can promote growth and enhance resistance;
the preparation method of the additive with gastrointestinal anti-stress function comprises the following steps:
(1) sterilizing Scolopendra, herba Lycopodii Serrati, Cinnabaris, fructus Viticis Simplicifoliae, semen Juglandis, Pseudobulbus Cremastrae seu pleiones, Zingiberis rhizoma, radix Angelicae sinensis, corm Eleocharitis, and herba Pteridis Multifidae;
(2) then, carrying out preliminary milling and crushing on centipede, Chinese pine, cinnabar, african amomum fruit, walnut, edible tulip, dried ginger, Chinese angelica, water chestnut and Chinese brake herb in each solid raw material, and then mixing and stirring each preliminary crushed raw material for 20-45 minutes;
(3) then adding the rest sodium bicarbonate, bacitracin zinc, glucose, fumaric acid, yeast chromium, whole cottonseed and rumen bypass fat into the mixture, and adding purified water to mix for 10-25 minutes until the mixture is uniformly mixed into paste;
(4) heating and drying the stirred pasty raw material at the temperature of 36-38 ℃ for 10-15 minutes;
(5) and crushing the dried mixed raw materials until the mixed raw materials pass through a 45-60-mesh sieve, weighing the mixed raw material powder, and subpackaging to obtain the finished product of the gastrointestinal anti-stress additive.
In the example, the weight ratio of the Chinese pine to the centipede is 1-1.5: 2-3.5.
In this example, the weight ratio of whole cottonseed to rumen bypass fat is 4.5-5.2: 1.3-1.5.
In the example, the following raw materials are included in parts by weight: 4 parts of sodium bicarbonate, 0.55 part of bacitracin zinc, 5 parts of glucose, 0.65 part of fumaric acid, 1.5 parts of yeast chromium, 5 parts of whole cottonseed, 18 parts of rumen bypass fat, 2 parts of centipede, 3 parts of Chinese pine, 5 parts of cinnabar, 2 parts of daub, 20 parts of walnut, 4 parts of edible tulip, 5 parts of dried ginger, 2 parts of angelica, 2 parts of water chestnut and 3 parts of Chinese brake herb.
In the present example, in the step (4), the stirred paste raw material is heated and dried, the drying temperature is 37.5 ℃, and the drying time is 12 minutes.
In the example, in the step (5), the dried mixed raw materials are crushed again until the mixed raw materials pass through a 55-mesh sieve, and then the mixed raw material powder is weighed and subpackaged to obtain the finished product of the gastrointestinal anti-stress additive.
In this example, the yeast chromium is added in an amount of 0.4 mg/kg per day in the feed, and can be supplemented with organic chromium, thereby improving productivity and enhancing immunity.
Example 2
The differences in this example 2 from example 1 are as follows:
the additive with the function of preventing gastrointestinal stress comprises the following raw materials in parts by weight:
5 parts of sodium bicarbonate, 0.6 part of bacitracin zinc, 4 parts of glucose, 0.55 part of fumaric acid, 1.5 parts of yeast chromium, 4 parts of all-cotton seeds, 12 parts of rumen bypass fat, 1 part of centipede, 1.5 parts of Chinese pine, 3 parts of cinnabar, 5 parts of daunomus seed, 25 parts of walnut, 4 parts of Indian iphigenia bulb, 6 parts of dried ginger, 2 parts of angelica, 2 parts of water chestnut and 2 parts of Chinese brake herb;
the preparation method of the additive with gastrointestinal anti-stress function comprises the following steps:
(1) sterilizing Scolopendra, herba Lycopodii Serrati, Cinnabaris, fructus Viticis Simplicifoliae, semen Juglandis, Pseudobulbus Cremastrae seu pleiones, Zingiberis rhizoma, radix Angelicae sinensis, corm Eleocharitis, and herba Pteridis Multifidae;
(2) then, carrying out preliminary milling and crushing on centipede, Chinese pine, cinnabar, african amomum fruit, walnut, edible tulip, dried ginger, Chinese angelica, water chestnut and Chinese brake herb in each solid raw material, and then mixing and stirring each preliminarily crushed raw material for 30 minutes;
(3) then adding the rest sodium bicarbonate, bacitracin zinc, glucose, fumaric acid, yeast chromium, whole cottonseed and rumen bypass fat into the mixture, and adding purified water to mix for 18 minutes until the mixture is uniformly mixed into paste;
(4) heating and drying the stirred pasty raw material at 36-38 ℃ for 10 minutes;
(5) and crushing the dried mixed raw materials until the mixed raw materials pass through a 60-mesh sieve, weighing the mixed raw material powder, and subpackaging to obtain the finished product of the gastrointestinal anti-stress additive.
In the example, the weight ratio of the Chinese pine to the centipede is 1-1.2: 2-3.3.
In this example, the weight ratio of whole cottonseed to rumen bypass fat is 4.5-5.1: 1.3-1.4.
Example 3
The differences in this example 3 from example 1 are as follows:
the additive with the function of gastrointestinal anti-stress comprises the following raw materials in parts by weight:
8 parts of sodium bicarbonate, 0.65 part of bacitracin zinc, 9 parts of glucose, 0.65 part of fumaric acid, 1.5 parts of yeast chromium, 3 parts of all-cotton seeds, 10 parts of rumen bypass fat, 2 parts of centipedes, 5 parts of Chinese pine, 2 parts of cinnabar, 2 parts of daunomus seed, 20 parts of walnut, 2 parts of Indian iphigenia bulb, 3 parts of dried ginger, 2 parts of angelica, 2 parts of water chestnut and 1 part of Chinese brake herb;
the preparation method of the additive with gastrointestinal anti-stress function comprises the following steps:
(1) sterilizing Scolopendra, herba Lycopodii Serrati, Cinnabaris, fructus Viticis Simplicifoliae, semen Juglandis, Pseudobulbus Cremastrae seu pleiones, Zingiberis rhizoma, radix Angelicae sinensis, corm Eleocharitis, and herba Pteridis Multifidae;
(2) then, carrying out preliminary milling and crushing on centipede, Chinese pine, cinnabar, african amomum fruit, walnut, Indian iphigenia bulb, dried ginger, Chinese angelica, water chestnut and Chinese brake herb in each solid raw material, and then mixing and stirring each preliminarily crushed raw material for 40 minutes;
(3) then adding the rest sodium bicarbonate, bacitracin zinc, glucose, fumaric acid, yeast chromium, whole cottonseed and rumen bypass fat into the mixture, and adding purified water to mix for 15 minutes until the mixture is uniformly mixed into paste;
(4) heating and drying the stirred pasty raw material at 36-38 ℃ for 13 minutes;
(5) and crushing the dried mixed raw materials until the mixed raw materials pass through a 55-mesh sieve, weighing the mixed raw material powder, and subpackaging to obtain the finished product of the gastrointestinal anti-stress additive.
The raw materials in the invention have the following medicinal properties and pharmacology:
sodium bicarbonate, sodium bicarbonate (i.e., baking soda) is an electrolyte additive and acid-base modifier; the buffer capacity of the organism is ensured to be strong, and the pH value and the alkali storage of blood are improved, so that the endocrine system can work and operate normally when suffering from strong stress; can relieve heat stress, and can improve the milk fat rate and total solid content of cat and dog by adding daily sodium bicarbonate into daily ration of cat and dog, so as to improve milk yield.
The bacitracin zinc has a good application effect on relieving heat stress of pets; the action mechanism is that the composition can inhibit the formation of pathogenic bacteria cell walls, influence the synthesis of pathogenic bacteria protein, influence the functions of certain cell membranes and finally inhibit or kill pathogenic bacteria; can improve the structure of the intestinal wall, thin the intestinal wall and increase the absorption of nutrients; can also increase the activity of some enzymes and regulate the metabolism of the organism; the high temperature resistant effect is obvious; the zinc bacitracin allows pets to use most of their energy for weight gain and to reduce thermogenesis in the body.
Glucose, heat stress can increase blood viscosity and reduce blood osmotic pressure, so that heat dissipation in livestock and poultry bodies is affected; and the glucose is added into the drinking water, so that the influence of heat stress on the blood property can be relieved, the heat dissipation is improved, toxic metabolites in the blood can be reduced, the death rate is reduced, and the weight gain is improved.
Fumaric acid, an acidifier, can regulate acid-base balance, and prevent blood pH increase caused by heat stress; fumaric acid has tranquilizing effect, and can inhibit central nerve, reduce body activity, and reduce thermogenesis.
Chromium can influence the reaction of animals to stress by changing the secretion of cortical hormone and enhancing the utilization of glucose, has the function of slowing down stress, reduces the level of serum cortisol, improves daily gain and feed conversion rate, enhances the immune function and reduces the morbidity; the common organic chromium is chromium nicotinate, chromium picolinate, chromium yeast, chromium amino acid, chromium protein and the like, wherein the chromium picolinate and chromium yeast have good use effects.
Whole cottonseed and rumen bypass fat can supplement energy loss caused by anorexia during heat stress; the influence of heat stress on cats and dogs can be relieved by adding 10.3% of whole cottonseed or adding 2.6% of rumen bypass fat or adding 5.2% of whole cottonseed and 1.3% of rumen bypass fat into the daily ration of cats and dogs, so that the dry matter feed intake and the milk production are increased;
scolopendra and herba Lycopodii can resist convulsion; cinnabar, fructus Formosanae, etc. have sedative and hypnotic effects; herba plantaginis has effects in clearing away heat, relieving summer-heat, and cooling.
Walnut: has effects of benefiting qi, nourishing blood, warming lung, moisturizing intestine, and treating hernia pain. And (3) edible tulip: has blood circulation promoting effect, contains abundant proteins, and has effects of promoting growth and enhancing resistance. Dried ginger: has effects in warming spleen and stomach, dispelling cold, restoring yang, dredging collaterals, warming lung, and eliminating phlegm; especially has unique effects of warming stomach and dredging collaterals. Chinese angelica: pungent, warm and nontoxic, and has effects of invigorating qi, regulating blood, moistening dryness, smoothing intestine, and enhancing immunity. Water chestnut: has effects in promoting salivation, clearing away heat, eliminating phlegm, clearing away stomach fire, and purging kidney heat. Herba Pteridis Multifidae: the Chinese medicinal composition has slightly bitter taste, enters liver, kidney and large intestine channels, has the effects of clearing heat, promoting diuresis, relieving swelling, detoxifying and the like, is used for treating dysentery and enteritis, is beneficial to reducing gastrointestinal diseases, and further has the effect of preventing gastrointestinal stress.
The average values of the 30-day cycle growth in the different experimental groups for the additives prepared in examples 1 to 3, compared to the conventional additives, are shown in the following table:
as can be seen from the table, compared with the conventional additive, the additive with the function of gastrointestinal anti-stress provided by the invention has the advantages that the pH value and alkali storage of blood, the high temperature resistant effect, the activity increase of enzyme, the feed intake increase, the weight gain and the like are obviously improved, and meanwhile, the diarrhea rate of intestines and stomach, the reduction rate of toxic metabolites and the like are obviously reduced; and example 3 is the most preferred example.
The additive with the function of preventing the stomach from being stressed, which is provided by the invention, has a better effect on preventing the stomach from being stressed particularly in the feeding of some cats and dogs, is beneficial to ensuring that an organism has strong buffering capacity and improving the pH value and alkali storage of blood by adding the sodium bicarbonate, so that an endocrine system can normally work and operate when suffering from strong stress, the heat stress can be relieved, the daily sodium bicarbonate is added into daily ration of the cats and dogs, the milk fat rate and the total solid content of the cats and dogs can be improved, and the milk yield is improved; by adding bacitracin zinc, the pet can use most of energy for weight gain, so that the heat generation in vivo is reduced, the activity of enzyme can be increased, the metabolism of an organism is regulated, and the high temperature resistant effect is more obvious; by adding glucose, the influence of heat stress on blood properties can be relieved, heat dissipation is improved, toxic metabolites in blood can be reduced, the death rate is reduced, and weight gain is improved; by adding fumaric acid, acid-base balance can be adjusted, blood pH increase caused by heat stress can be prevented, tranquilizing effect can be achieved, and organism activity can be reduced, thereby reducing heat production; by adding the yeast chromium, the daily gain and the feed conversion rate are improved, the immune function is enhanced, and the morbidity is reduced; by adding the whole cottonseed and rumen bypass fat, energy loss caused by appetite loss can be supplemented during heat stress, and the influence of heat stress on cats and dogs can be relieved; in addition, Scolopendra and herba Lycopodii can resist convulsion; cinnabar, fructus Formosanae, etc. have sedative and hypnotic effects; herba plantaginis has effects in clearing away heat, relieving summer-heat, and cooling; the edible tulip can promote growth and enhance resistance; the water chestnut has the functions of clearing stomach fire and purging kidney heat; and through the addition of phoenix-tail fern, help reducing the emergence of stomach disease, further played the effect that the stomach was prevented stress, finally, can make the stomach in the pet feeding prevent stress the effect better, and the effect is more comprehensive, has satisfied the production demand that current pet was raised greatly.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (9)
1. The additive with the function of preventing gastrointestinal stress is characterized by comprising the following raw materials in parts by weight:
2-8 parts of sodium bicarbonate, 0.55-0.65 part of bacitracin zinc, 4-9 parts of glucose, 0.55-0.65 part of fumaric acid, 0.5-1.5 parts of chromium yeast, 1-7 parts of whole cottonseed, 10-20 parts of rumen bypass fat, 1-5 parts of centipede, 1-5 parts of Chinese pine, 2-5 parts of cinnabar, 2-7 parts of daub, 8-25 parts of walnut, 2-4 parts of edible tulip, 3-6 parts of dried ginger, 2-6 parts of angelica, 2-4 parts of water chestnut and 1-3 parts of phoenix-tail fern;
the additive with intestine and stomach stress prevention can improve the heat stress symptom of the pet, simultaneously can obviously increase the daily feed intake and average daily gain of the pet, can promote growth and enhance resistance;
the preparation method of the additive with gastrointestinal anti-stress function comprises the following steps:
(1) sterilizing Scolopendra, herba Lycopodii Serrati, Cinnabaris, fructus Viticis Simplicifoliae, semen Juglandis, Pseudobulbus Cremastrae seu pleiones, Zingiberis rhizoma, radix Angelicae sinensis, corm Eleocharitis, and herba Pteridis Multifidae;
(2) then, carrying out preliminary milling and crushing on centipede, Chinese pine, cinnabar, african amomum fruit, walnut, edible tulip, dried ginger, Chinese angelica, water chestnut and Chinese brake herb in each solid raw material, and then mixing and stirring each preliminary crushed raw material for 20-45 minutes;
(3) then adding the rest sodium bicarbonate, bacitracin zinc, glucose, fumaric acid, yeast chromium, whole cottonseed and rumen bypass fat into the mixture, and adding purified water to mix for 10-25 minutes until the mixture is uniformly mixed into paste;
(4) heating and drying the stirred pasty raw material at the temperature of 36-38 ℃ for 10-15 minutes;
(5) and crushing the dried mixed raw materials until the mixed raw materials pass through a 45-60-mesh sieve, weighing the mixed raw material powder, and subpackaging to obtain the finished product of the gastrointestinal anti-stress additive.
2. The additive with gastrointestinal anti-stress function as claimed in claim 1, wherein the weight ratio of the pine to the centipede is 1-1.5: 2-3.5.
3. The additive for preventing gastrointestinal stress according to claim 1, wherein the weight ratio of whole cottonseed to rumen bypass fat is 4.5-5.2: 1.3-1.5.
4. The additive with gastrointestinal anti-stress function according to claim 1 is characterized by comprising the following raw materials in parts by weight: 2-6 parts of sodium bicarbonate, 0.55-0.6 part of bacitracin zinc, 4-8 parts of glucose, 0.55-0.65 part of fumaric acid, 0.5-1.5 parts of chromium yeast, 1-7 parts of whole cottonseed, 10-18 parts of rumen bypass fat, 1-5 parts of centipede, 1-4 parts of Chinese pine, 2-5 parts of cinnabar, 2-5 parts of daub, 8-23 parts of walnut, 2-4 parts of edible tulip, 3-6 parts of dried ginger, 2-5 parts of angelica, 2-4 parts of water chestnut and 1-3 parts of phoenix-tail fern.
5. The additive with gastrointestinal anti-stress function according to claim 4, which is characterized by comprising the following raw materials in parts by weight: 4 parts of sodium bicarbonate, 0.55 part of bacitracin zinc, 5 parts of glucose, 0.65 part of fumaric acid, 1.5 parts of yeast chromium, 5 parts of whole cottonseed, 18 parts of rumen bypass fat, 2 parts of centipede, 3 parts of Chinese pine, 5 parts of cinnabar, 2 parts of daub, 20 parts of walnut, 4 parts of edible tulip, 5 parts of dried ginger, 2 parts of angelica, 2 parts of water chestnut and 3 parts of Chinese brake herb.
6. The additive for preventing gastrointestinal stress according to claim 1, wherein in the step (4), the stirred pasty raw material is heated and dried at a temperature of 36-37.5 ℃ for 12-15 minutes.
7. The additive for preventing gastrointestinal stress as claimed in claim 6, wherein in the step (4), the stirred pasty raw material is heated and dried at 37.5 ℃ for 12 minutes.
8. The additive for preventing gastrointestinal stress according to claim 1, wherein in the step (5), the dried mixed raw materials are crushed again until the mixed raw materials pass through a 55-mesh sieve, and then the mixed raw material powder is weighed and subpackaged to obtain a finished product of the additive for preventing gastrointestinal stress.
9. The additive with gastrointestinal anti-stress function as claimed in claim 1, wherein the yeast chromium is added in an amount of 0.4 mg/kg in the feed per day, so that organic chromium can be supplemented, the production performance is improved, and the immunity is enhanced.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108338277A (en) * | 2018-01-31 | 2018-07-31 | 上海普缇康生物技术有限公司 | A kind of pet stomach is good for the preparation method of additive for microbe feedstuff |
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| CN108338277A (en) * | 2018-01-31 | 2018-07-31 | 上海普缇康生物技术有限公司 | A kind of pet stomach is good for the preparation method of additive for microbe feedstuff |
| CN113273639A (en) * | 2021-04-28 | 2021-08-20 | 广州双图生物科技有限公司 | Preparation method of probiotic-containing fresh-keeping insects |
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