CN114588238A - Traditional Chinese medicine composition for treating hypertension - Google Patents

Traditional Chinese medicine composition for treating hypertension Download PDF

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Publication number
CN114588238A
CN114588238A CN202210244635.0A CN202210244635A CN114588238A CN 114588238 A CN114588238 A CN 114588238A CN 202210244635 A CN202210244635 A CN 202210244635A CN 114588238 A CN114588238 A CN 114588238A
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China
Prior art keywords
parts
raw
radix
fructus
blood
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CN202210244635.0A
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Chinese (zh)
Inventor
潘玉杰
覃广源
黄磁钢
闫贇
孙田甜
陈华容
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Guizhou Bailing Enterprise Group Parmaceutial Co ltd
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Guizhou Bailing Enterprise Group Parmaceutial Co ltd
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Priority to CN202210244635.0A priority Critical patent/CN114588238A/en
Publication of CN114588238A publication Critical patent/CN114588238A/en
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Abstract

The invention discloses a traditional Chinese medicine composition for treating hypertension, which is prepared from raw materials of ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus membranaceus, dragon's blood, red peony root, ground beetle, perilla fruit, safflower, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin leaf, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, loranthus parasiticus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, red bean, radix rehmanniae, radix ophiopogonis, poria cocos, poria with hostwood, Chinese yam, cortex moutan, achyranthes bidentata, plantain herb, salvia miltiorrhiza, earthworm, peach red, rheum officinale, raw hawthorn, cassia seed, black bean, spina date seed, schisandra chinensis, raw dragon's blood and pseudo-ginseng. The invention has the characteristics of improving the treatment effect on hypertension and shortening the treatment time.

Description

Traditional Chinese medicine composition for treating hypertension
Technical Field
The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating hypertension.
Background
Hypertension refers to the condition that under the condition of no antihypertensive drug, the systolic pressure is more than or equal to 140mmHg and/or the diastolic pressure is more than or equal to 90mmHg, and the hypertension is divided into 1, 2 and 3 grades according to the blood pressure level. The simple systolic hypertension is obtained by the list that the systolic pressure is more than or equal to 140mmHg and the diastolic pressure is less than 90 mmHg. Hypertension is a common clinical disease and also the most main risk factor of cardiovascular and cerebrovascular diseases, and is one of the main diseases which endanger human health.
Hypertension, called as "wind dizziness" in traditional Chinese medicine, belongs to the categories of "dizziness", "headache", "apoplexy" and the like in traditional Chinese medicine. Because of imbalance of emotions, improper diet, chronic illness, overstrain and congenital deficiency, yin-yang imbalance, viscera qi-blood imbalance, clear orifices losing nourishment, dizziness, headache, neck and back rigidity, numbness of hands and feet, red face, rising fire, insomnia, memory deterioration and the like are caused. The western medicine considers that hypertension is an independent disease of the increase of the blood pressure of systemic circulation arteries and the damage of vascular nerves caused by the imbalance of arterial vascular resistance and blood flow, and is a common clinical syndrome. Can be divided into primary hypertension and secondary hypertension. Therefore, clinical medication is mainly aimed at dredging blood vessels or reducing blood flow.
The main clinical treatment for hypertension is western medicines, but the western medicines have side effects of dizziness, headache and the like. In view of the fact that traditional Chinese medicines have slow action, but have higher safety, better effectiveness and lasting drug effect compared with western medicines, screening and extracting effective antihypertensive components from natural traditional Chinese medicines becomes one of important ways for developing new antihypertensive medicines. However, the efficacy of the traditional Chinese medicine for treating hypertension still cannot reach an ideal degree, and the action time is too long.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating hypertension. The invention has the characteristics of improving the effect of treating hypertension and shortening the treatment time.
The technical scheme of the invention is as follows: a traditional Chinese medicine composition for treating hypertension is prepared from raw materials of ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beeltle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu vine, castor bean, raw abalone shell, eucommia bark, selfheal, folium harlejae praeparatum, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, parasitic loranthus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, phaseolus calcaratus, dried rehmannia root, radix ophiopogonis, poria cocos, poria with hostwood, Chinese yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria rhynchophylla, earthworm, peach red, rheum officinale, raw hawthorn, semen cassiae, black beans, spina date seeds, schisandra chinensis, raw black dragon's bones and pseudo-ginseng.
In the traditional Chinese medicine composition for treating hypertension, the ratio of the total dose of the ligusticum wallichii, the cassia twig, the fructus aurantii and the frankincense to the total dose of other raw materials is 1: 2-5.
In the traditional Chinese medicine composition for treating hypertension, the ratio of the total dose of the ligusticum wallichii, the cassia twig, the fructus aurantii and the frankincense to the total dose of other raw materials is 1: 3.
In the traditional Chinese medicine composition for treating hypertension, the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 15-25 parts of ligusticum wallichii, 10-20 parts of cassia twig, 10-25 parts of fructus aurantii, 5-20 parts of frankincense, 10-20 parts of astragalus membranaceus, 4-7 parts of dragon's blood, 3-8 parts of red peony root, 5-10 parts of ground beetle, 2-8 parts of perilla fruit, 2-10 parts of safflower, 3-6 parts of myrrh, 2-6 parts of herba lycopi, 3-5 parts of curcuma zedoary, 3-6 parts of rhizoma alismatis, 7-13 parts of kudzu vine, 4-6 parts of castor bean, 8-15 parts of raw abalone shell, 2-6 parts of eucommia bark, 2-4 parts of selfheal, 2-6 parts of clerodendron bungeanum leaf, 3-6 parts of setaria leaf, 5-10 parts of mulberry leaf, 3-5 parts of white mulberry root-bark, 3-5 parts of parasitic loranthus, 5-10 parts of wild chrysanthemum, 2-6 parts of semen raphani, 3-7 parts of Chinese yam, 3-6 parts of fructus viticis, 5-10 parts of radish seed, 5-10 parts of small red bean, 2-6 parts of rehmannia root, 3-5 parts of poria cocos, 6 parts of cortex moutan, 6 parts of cortex, 3-8 parts of cortex moutan, 3-5 parts of fructus lycii, 4-5 parts of poria, 4-6 parts of poria cocos, 4-6 parts of poria cocos, 4 parts of poria, 4-10 parts of achyranthes bidentata, 2-6 parts of plantain herb, 4-8 parts of salvia miltiorrhiza, 2-4 parts of uncaria, 2-8 parts of earthworm, 3-10 parts of peach blossom, 2-8 parts of rheum officinale, 4-10 parts of raw hawthorn, 5-8 parts of semen cassiae, 4-10 parts of black bean, 3-5 parts of spina date seed, 3-7 parts of schisandra chinensis, 2-5 parts of raw dragon's blood and 5-10 parts of pseudo-ginseng.
In the traditional Chinese medicine composition for treating hypertension, the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 20 parts of szechuan lovage rhizome, 17 parts of cassia twig, 25 parts of bitter orange, 15 parts of frankincense, 20 parts of astragalus root, 5 parts of dragon's blood, 6 parts of red paeony root, 8 parts of ground beeltle, 3 parts of perilla fruit, 2 parts of safflower, 5 parts of myrrh, 4 parts of hiraute shiny bugleweed herb, 4 parts of zedoary, 4 parts of oriental waterplantain rhizome, 10 parts of kudzu, 5 parts of castor bean, 14 parts of raw abalone shell, 3 parts of eucommia bark, 3 parts of common selfheal fruit-spike, 5 parts of harlequin leaf, 5 parts of herba siegesbeckiae, 8 parts of mulberry leaf, 4 parts of white mulberry root-bark and 4 parts of parasitic loranthus, 6 parts of wild chrysanthemum, 4 parts of radish seed, 5 parts of tribulus terrestris, 4 parts of fructus viticis, 8 parts of phaseolus calcaratus, 4 parts of radix rehmanniae, 4 parts of radix ophiopogonis, 6 parts of poria cocos, 3 parts of poria with hostwood, 6 parts of Chinese yam, 4 parts of cortex moutan, 4 parts of radix achyranthis bidentatae, 4 parts of plantain herb, 4 parts of salvia miltiorrhiza, 3 parts of uncaria, 4 parts of lumbricus, 4 parts of peach red, 3 parts of rheum officinale, 5 parts of raw hawthorn, 5 parts of semen cassiae, 5 parts of black bean, 3 parts of spina date seed, 3 parts of schisandra chinensis, 2 parts of raw dragon's blood and 6 parts of pseudo-ginseng.
A Chinese medicinal composition for treating hypertension is prepared from rhizoma Ligustici Chuanxiong, ramulus Cinnamomi, fructus Aurantii, Olibanum, radix astragali, sanguis Draxonis, radix Paeoniae Rubra, Eupolyphaga Seu Steleophaga, fructus Perillae, Carthami flos, Myrrha, herba Lycopi, Curcumae rhizoma, Alismatis rhizoma, radix Puerariae, semen Ricini, Concha Haliotidis, Eucommiae cortex, Prunellae Spica, folium et ramulus Clerodendri Trichotomi, Siegesbeckiae herba, folium Mori, cortex Mori, herba Taxilli, flos Chrysanthemi Indici, Raphani semen, fructus Tribuli, fructus Vitics Simplicifoliae, semen Phaseoli, radix rehmanniae, radix Ophiopogonis, Poria, rhizoma Dioscoreae, cortex moutan, Achyranthis radix, herba plantaginis, Saviae Miltiorrhizae radix, ramulus Uncariae cum uncis, Lumbricus, exocarpium Persicae, radix et rhizoma Rhei, fructus crataegi, semen Cassiae, semen Sojae Atricolor, semen Ziziphi Spinosae, fructus Schisandrae, Os Draconis and Notoginseng radix by mixing, pulverizing, and making into desired dosage form.
In the preparation method, the dosage forms include tablets, capsules, granules, powder, dropping pills, decoctions and teas.
In the preparation method, when the dosage form is tablet, capsule, granule, powder, drop pill or pill, the ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red peony root, ground beetle, perillaseed, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu vine, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, loranthus parasiticus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, red bean, dried rehmannia root, radix ophiopogonis, poria cocos, poria with hostwood, yam, cortex moutan, achyranthes bidentatae, plantain herb, salvia miltiorrhiza, uncaria, earthworm, peach red peach blossom, rheum officinale, raw hawthorn, cassia seed, black bean, spina date seed, schisandra chinensis, raw dragon's bone and pseudo-ginseng are mixed, crushed, water in an amount which is 4-8 times of the total weight of the total raw materials is added, the total weight of the mixture is heated, decocted and extracted for 2-3 times or the mixture is added with alcohol in an amount of the total weight of the mixture, extracted for 2-3 times of the reflux extraction for 2-3 times, filtering for 2-3 hours each time, combining the filtrates, concentrating under reduced pressure to obtain dry extract, pulverizing into powder, adding pharmaceutically conventional adjuvants, and making into desired dosage forms.
In the preparation method, when the formulation is decoction, the ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beeltle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu vine root, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, mulberry bark, parasitic loranthus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, phaseolus calcaratus, dried rehmannia root, radix ophiopogonis, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria, earthworm, peach red, rheum officinale, raw hawthorn, cassia seed, black bean, spina date seed, raw hemerocallis castanomala, and pseudo-ginseng are mixed in proportion, ground, added for decoction, and decocted for 1-3 hours, and the decoction is taken to prepare the decoction.
In the preparation method, when the preparation is a tea, the ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beeltle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu vine, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, Chinese taxillus twig, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, red bean, dried rehmannia root, radix ophiopogonis, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria, earthworm, peach red, rheum officinale, raw hawthorn, cassia seed, black bean, spina date seed, schisandra chinensis, raw dragon's blood and pseudo-ginseng are cleaned, dried at 30-60 ℃, mixed according to a proportion, crushed, sterilized and packaged into a tea bag for making tea to prepare the tea.
The action mechanism of various raw materials in the invention is as follows:
astragalus root, radix astragali, has effects of invigorating qi, consolidating superficial resistance, inducing diuresis, and removing toxic substances; dragon's blood, it has effects of removing blood stasis, relieving pain, stopping bleeding and promoting granulation; radix Paeoniae Rubra has effects in clearing away heat, cooling blood, removing blood stasis, and relieving pain; ground beetle has the functions of breaking blood and removing stasis, and reuniting tendons and bones; perilla seed, fructus Perillae, has effects of lowering qi, eliminating phlegm, relieving asthma, and moisturizing intestine; safflower, which has the functions of promoting blood circulation, stimulating the menstrual flow, removing blood stasis and relieving pain; olibanum with effects of promoting blood circulation, expelling pathogenic wind, relaxing muscles and tendons, and relieving pain; myrrh with the functions of dissipating blood stasis, relieving pain, eliminating swelling and promoting vital function; herba Lycopi has effects in promoting blood circulation, regulating menstruation, dispelling blood stasis, resolving carbuncle, inducing diuresis, and relieving swelling; zedoary has the functions of promoting qi circulation, removing blood stasis, removing food retention and relieving pain; fructus Aurantii has effects in regulating qi-flowing, relieving epigastric distention, activating stagnancy, and relieving flatulence; rhizoma alismatis has the effects of promoting diuresis, excreting dampness, clearing heat, eliminating turbid pathogen and reducing blood fat; pueraria lobata has refreshing, anti-hangover, blood pressure lowering, and weight reducing effects; semen Ricini has effects of purgation, eliminating stagnation, detumescence and removing toxic substance; concha Haliotidis has effects of suppressing hyperactive liver, subsiding yang, removing liver heat, and improving eyesight; eucommia bark, cortex eucommiae, has the functions of nourishing liver and kidney and strengthening tendons and bones; spica Prunellae has effects of clearing liver-fire, improving eyesight, resolving hard mass and relieving swelling; folium et ramulus Clerodendri Trichotomi, it has effects of dispelling rheumatism, lowering blood pressure, etc.; herba Siegesbeckiae has effects of dispelling pathogenic wind, removing dampness, benefiting articulation, and removing toxic substance; folium Mori has effects in dispelling pathogenic wind and heat, clearing lung-heat, moistening dryness, calming liver, improving eyesight, cooling blood, and stopping bleeding; cortex Mori with effects of purging lung, relieving asthma, inducing diuresis, and relieving swelling; herba Taxilli with effects of dispelling pathogenic wind and removing dampness, nourishing liver and kidney, and strengthening tendons and bones; flos Chrysanthemi Indici with heat and toxic materials clearing away effect; radish seed, which has the functions of promoting digestion, relieving flatulence, descending qi and eliminating phlegm; fructus Tribuli with blood pressure lowering and diuretic effects; fructus Vitics Simplicifoliae has effects of dispelling pathogenic wind and heat, and refreshing mind; semen Phaseoli has effects of inducing diuresis to alleviate edema, removing toxic substance and expelling pus; radix rehmanniae has effects of clearing heat, promoting fluid production and cooling blood; the radix ophiopogonis has the effects of nourishing yin, promoting the production of body fluid, moistening lung and clearing away heart-fire; poria has effects in promoting diuresis, eliminating dampness, invigorating spleen, and calming heart; poria with hostwood has effects of calming heart, tranquilizing mind and tranquilizing; the Chinese yam has the functions of tonifying spleen and nourishing stomach, and promoting the production of body fluid and benefiting lung; cortex moutan has effects in clearing away heat, cooling blood, promoting blood circulation, dispelling blood stasis, and lowering blood pressure; achyranthes bidentata has the functions of nourishing liver and kidney, strengthening bones and muscles, removing blood stasis and stimulating the menstrual flow; herba plantaginis has effects of clearing away heat and toxic materials, promoting urination, and nourishing lung; the salvia miltiorrhiza has the functions of removing blood stasis, relieving pain, activating blood and stimulating menstrual flow; rhizoma Ligustici Chuanxiong has effects of promoting blood circulation, activating qi-flowing, dispelling pathogenic wind and relieving pain; ramulus Uncariae cum uncis with tranquilizing and blood pressure lowering effects; lumbricus with effects of lowering blood pressure, dredging meridian passage; peach red has the functions of promoting blood circulation to disperse blood clots, dissipating blood stasis and relieving pain; the radix et rhizoma Rhei has effects of promoting intestinal peristalsis and resisting inflammation; ramulus Cinnamomi has effects of warming and dredging channels and collaterals, and promoting urination; fructus crataegi has effects of resolving food stagnation, invigorating stomach, promoting blood circulation, removing blood stasis, and lowering blood pressure; semen Cassiae has effects of lowering blood pressure and reducing blood lipid; the black bean has the effects of relieving exterior syndrome, clearing heat, and strengthening tendons and bones; semen Ziziphi Spinosae with effects of nourishing liver, lowering blood pressure, tranquilizing mind and calming heart; fructus Schisandrae has astringent, qi invigorating, salivation promoting, kidney invigorating, and heart calming effects; the raw dragon oyster has the functions of relieving convulsion, soothing the nerves, calming the liver and suppressing yang; notoginseng radix has effects of removing blood stasis, stopping bleeding, relieving swelling and relieving pain.
Compared with the prior art, the traditional Chinese medicine composition adopts various traditional Chinese medicinal materials with the functions of dredging blood vessels, removing stasis and dissipating stasis, adopts various traditional Chinese medicinal materials with the function of reducing blood pressure, is matched with the traditional Chinese medicinal materials with the function of inducing diuresis to reduce edema, can give consideration to other pathological links of hypertension, has the functions of improving microcirculation, protecting vascular endothelium, regulating vasoactive substances, protecting kidney-liver-blood vessels and other systems, improves the effect of treating hypertension, and shortens the treatment time of hypertension; the traditional Chinese medicine composition is matched with various medicinal materials for strengthening tendons and bones, so that the resistance of a human body is enhanced, the influence of various side effects on the human body is reduced, and the medicinal materials are compatible with one another, so that the traditional Chinese medicine composition is mild in effect and small in side effect.
Detailed Description
The present invention is further illustrated by the following examples, which are not to be construed as limiting the invention.
Example 1: a traditional Chinese medicine composition for treating hypertension comprises the following raw material medicines in parts by weight: 25 parts of szechuan lovage rhizome, 20 parts of cassia twig, 25 parts of bitter orange, 20 parts of frankincense, 10 parts of astragalus root, 7 parts of dragon's blood, 8 parts of red paeony root, 10 parts of ground beeltle, 8 parts of perilla fruit, 8 parts of safflower, 6 parts of myrrh, 6 parts of hiraute shiny bugleweed herb, 5 parts of zedoary, 6 parts of oriental waterplantain rhizome, 13 parts of kudzu vine root, 6 parts of castor bean, 15 parts of raw abalone shell, 6 parts of eucommia bark, 4 parts of common selfheal fruit-spike, 6 parts of harlequin leaf, 6 parts of herba siegesbeckiae, 10 parts of mulberry leaf, 5 parts of white mulberry root-bark and 5 parts of Chinese taxillus twig, 10 parts of wild chrysanthemum flower, 6 parts of radish seed, 7 parts of tribulus terrestris, 6 parts of fructus viticis, 10 parts of phaseolus calcaratus, 6 parts of radix rehmanniae, 5 parts of radix ophiopogonis, 8 parts of poria cocos, 5 parts of poria with hostwood, 8 parts of Chinese yam, 6 parts of cortex moutan, 10 parts of radix achyranthis bidentatae, 6 parts of plantain herb, 8 parts of salvia miltiorrhiza, 4 parts of uncaria, 8 parts of earthworm, 10 parts of peach red, 8 parts of rheum officinale, 10 parts of raw hawthorn, 8 parts of semen cassiae, 8 parts of black bean, 5 parts of spina date seed, 7 parts of schisandra chinensis, 5 parts of raw oyster shell and 10 parts of pseudo-ginseng.
Mixing rhizoma ligustici wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beeltle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu vine root, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, parasitic loranthus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, red bean, dried rehmannia root, radix ophiopogonis, poria cocos, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, red sage root, uncaria, earthworm, peach red, rheum officinale, raw hawthorn fruit, cassia seed, black bean, spina date seed, schisandra chinensis, raw dragon's blood and pseudo-ginseng, crushing, adding water in an amount which is 4-8 times of the weight of the total raw materials, heating and decocting for 2-3 times or adding alcohol in an amount which is 4-8 times of the total weight of the total raw materials, refluxing and extracting for 2-3 times, each time, filtering, combining filtrates, concentrating under reduced pressure to obtain dry paste, crushing the powder, adding pharmaceutically conventional adjuvants, and making into desired dosage form. The required dosage forms are tablets, capsules, granules, powder, dripping pills or pills and other pharmacologically reasonable dosage forms.
The dosage of the invention depends on the specific dosage form, the age, the weight, the health condition and other factors of the patient. As a guide, the medicine is taken 1-3 times a day, 5-10 g each time and 1h after meal.
Example 2: a traditional Chinese medicine composition for treating hypertension comprises the following raw material medicines in parts by weight: 15 parts of szechuan lovage rhizome, 10 parts of cassia twig, 10 parts of bitter orange, 5 parts of frankincense, 20 parts of astragalus root, 4 parts of dragon's blood, 3 parts of red paeony root, 5 parts of ground beeltle, 2 parts of perilla fruit, 2 parts of safflower, 3 parts of myrrh, 2 parts of hiraute shiny bugleweed herb, 3 parts of zedoary, 3 parts of oriental waterplantain rhizome, 7 parts of kudzu, 4 parts of castor bean, 8 parts of raw abalone shell, 2 parts of eucommia bark, 2 parts of common selfheal fruit-spike, 2 parts of harlequin leaf, 3 parts of herba siegesbeckiae, 5 parts of mulberry leaf, 3 parts of white mulberry root-bark and 3 parts of parasitic loranthus, 5 parts of wild chrysanthemum, 2 parts of radish seed, 3 parts of tribulus terrestris, 3 parts of fructus viticis, 5 parts of phaseolus calcaratus, 2 parts of radix rehmanniae, 3 parts of radix ophiopogonis, 6 parts of poria cocos, 3 parts of poria with hostwood, 4 parts of Chinese yam, 4 parts of cortex moutan, 4 parts of radix achyranthis bidentatae, 2 parts of plantain herb, 4 parts of salvia miltiorrhiza, 2 parts of uncaria, 2 parts of earthworm, 3 parts of peach red, 2 parts of rheum officinale, 4 parts of raw hawthorn, 5 parts of semen cassiae, 4 parts of black bean, 3 parts of spina date seed, 3 parts of schisandra chinensis, 2 parts of raw Japanese oyster and 5 parts of pseudo-ginseng.
Mixing rhizoma ligustici wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beeltle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu vine root, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, parasitic loranthus, wild chrysanthemum, radish seed, tribulus terrestris, fructus viticis, red bean, radix rehmanniae, radix ophiopogonis, poria cocos, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria, earthworm, peach red, rheum officinale, raw hawthorn, semen cassiae, black bean, spina date seed, schisandra chinensis, raw dragon's blood and pseudo-ginseng in proportion, crushing, adding and decocting for 1-3 hours, and taking decoction to prepare decoction.
The dosage of the invention depends on the specific dosage form, the age, the weight, the health condition and other factors of the patient. As a guide, the medicine is taken for 2 times a day, wherein 100-200 ml is taken each time and is taken 1h after meals.
Example 3: a traditional Chinese medicine composition for treating hypertension comprises the following raw material medicines in parts by weight: 20 parts of szechuan lovage rhizome, 17 parts of cassia twig, 25 parts of bitter orange, 15 parts of frankincense, 20 parts of astragalus root, 5 parts of dragon's blood, 6 parts of red paeony root, 8 parts of ground beeltle, 3 parts of perilla fruit, 2 parts of safflower, 5 parts of myrrh, 4 parts of hiraute shiny bugleweed herb, 4 parts of zedoary, 4 parts of oriental waterplantain rhizome, 10 parts of kudzu, 5 parts of castor bean, 14 parts of raw abalone shell, 3 parts of eucommia bark, 3 parts of common selfheal fruit-spike, 5 parts of harlequin leaf, 5 parts of herba siegesbeckiae, 8 parts of mulberry leaf, 4 parts of white mulberry root-bark and 4 parts of parasitic loranthus, 6 parts of wild chrysanthemum, 4 parts of radish seed, 5 parts of tribulus terrestris, 4 parts of fructus viticis, 8 parts of phaseolus calcaratus, 4 parts of radix rehmanniae, 4 parts of radix ophiopogonis, 6 parts of poria cocos, 3 parts of poria with hostwood, 6 parts of Chinese yam, 4 parts of cortex moutan, 4 parts of radix achyranthis bidentatae, 4 parts of plantain herb, 4 parts of salvia miltiorrhiza, 3 parts of uncaria, 4 parts of lumbricus, 4 parts of peach red, 3 parts of rheum officinale, 5 parts of raw hawthorn, 5 parts of semen cassiae, 5 parts of black bean, 3 parts of spina date seed, 3 parts of schisandra chinensis, 2 parts of raw dragon's blood and 6 parts of pseudo-ginseng.
Cleaning rhizoma ligustici wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, radix paeoniae rubra, ground beeltle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu, castor bean, raw concha haliotidis, eucommia ulmoides, selfheal, harlequin leaf, herba siegesbeckiae, folium mori, cortex mori radicis, parasitic loranthus, wild chrysanthemum, radish seed, tribulus terrestris, fructus viticis, red bean, dried rehmannia root, radix ophiopogonis, poria with hostwood, Chinese yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria, earthworm, peach red, rheum officinale, raw hawthorn, semen cassiae, black bean, spina date seed, schisandra chinensis, raw dragon oyster and pseudo-ginseng, drying at 30-60 ℃, mixing according to a certain proportion, crushing, sterilizing, filling into tea bags for tea making to prepare tea, wherein each tea bag contains 10-15 g of medicament.
The traditional Chinese medicine composition can be used as tea drink for daily use, has the effects of preventing and treating hypertension, has no toxic or side effect, is convenient to drink, and can be brewed repeatedly.

Claims (10)

1. A traditional Chinese medicine composition for treating hypertension is characterized in that: the raw materials of the traditional Chinese medicine composition comprise ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beetle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, loranthus parasiticus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, phaseolus calcaratus, radix rehmanniae, radix ophiopogonis, poria cocos, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, earthworm, peach blossom, rheum officinale, raw hawthorn, semen cassiae, black soya bean, spina date seed, schisandra chinensis, raw black dragon's bone and pseudo-ginseng.
2. The traditional Chinese medicine composition for treating hypertension according to claim 1, which is characterized in that: wherein the ratio of the total dose of the ligusticum wallichii, the cassia twig, the fructus aurantii and the frankincense to the total dose of other raw materials is 1: 2-5.
3. The traditional Chinese medicine composition for treating hypertension according to claim 2, which is characterized in that: wherein the ratio of the total dose of the ligusticum wallichii, the cassia twig, the fructus aurantii and the frankincense to the total dose of other raw materials is 1: 3.
4. The traditional Chinese medicine composition for treating hypertension according to claim 1, which is characterized in that: the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 15-25 parts of ligusticum wallichii, 10-20 parts of cassia twig, 10-25 parts of fructus aurantii, 5-20 parts of frankincense, 10-20 parts of astragalus membranaceus, 4-7 parts of dragon's blood, 3-8 parts of red peony root, 5-10 parts of ground beetle, 2-8 parts of perilla fruit, 2-10 parts of safflower, 3-6 parts of myrrh, 2-6 parts of herba lycopi, 3-5 parts of curcuma zedoary, 3-6 parts of rhizoma alismatis, 7-13 parts of kudzu vine, 4-6 parts of castor bean, 8-15 parts of raw abalone shell, 2-6 parts of eucommia bark, 2-4 parts of selfheal, 2-6 parts of harlequin glorybower leaf, 3-6 parts of viscus elegans, 5-10 parts of folium mori, 3-5 parts of cortex mori, 3-5 parts of parasitic loranthus, 5-10 parts of wild chrysanthemum flower, 2-6 parts of semen raphani, 3-7 parts of tribulus terrestris, 3-6 parts of fructus viticis, 5-10 parts of red bean, 2-6 parts of radix rehmanniae, 3-5 parts of poria cocos, 6 parts of poria cocos, 3-5 parts of poria cocos, 4 parts of rhizoma dioscoreae, 4 parts of poria cocos, 3-6 parts of poria cocos, 4-10 parts of achyranthes bidentata, 2-6 parts of plantain herb, 4-8 parts of salvia miltiorrhiza, 2-4 parts of uncaria, 2-8 parts of earthworm, 3-10 parts of peach blossom, 2-8 parts of rheum officinale, 4-10 parts of raw hawthorn, 5-8 parts of semen cassiae, 4-10 parts of black bean, 3-5 parts of spina date seed, 3-7 parts of schisandra chinensis, 2-5 parts of raw dragon's blood and 5-10 parts of pseudo-ginseng.
5. The traditional Chinese medicine composition for treating hypertension according to claim 4, which is characterized in that: the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 20 parts of szechuan lovage rhizome, 17 parts of cassia twig, 25 parts of bitter orange, 15 parts of frankincense, 20 parts of astragalus root, 5 parts of dragon's blood, 6 parts of red paeony root, 8 parts of ground beeltle, 3 parts of perilla fruit, 2 parts of safflower, 5 parts of myrrh, 4 parts of hiraute shiny bugleweed herb, 4 parts of zedoary, 4 parts of oriental waterplantain rhizome, 10 parts of kudzu, 5 parts of castor bean, 14 parts of raw abalone shell, 3 parts of eucommia bark, 3 parts of common selfheal fruit-spike, 5 parts of harlequin leaf, 5 parts of herba siegesbeckiae, 8 parts of mulberry leaf, 4 parts of white mulberry root-bark and 4 parts of parasitic loranthus, 6 parts of wild chrysanthemum, 4 parts of radish seed, 5 parts of tribulus terrestris, 4 parts of fructus viticis, 8 parts of phaseolus calcaratus, 4 parts of radix rehmanniae, 4 parts of radix ophiopogonis, 6 parts of poria cocos, 3 parts of poria with hostwood, 6 parts of Chinese yam, 4 parts of cortex moutan, 4 parts of radix achyranthis bidentatae, 4 parts of plantain herb, 4 parts of salvia miltiorrhiza, 3 parts of uncaria, 4 parts of lumbricus, 4 parts of peach red, 3 parts of rheum officinale, 5 parts of raw hawthorn, 5 parts of semen cassiae, 5 parts of black bean, 3 parts of spina date seed, 3 parts of schisandra chinensis, 2 parts of raw dragon's blood and 6 parts of pseudo-ginseng.
6. The preparation method of the traditional Chinese medicine composition for treating hypertension according to claim 1, which is characterized by comprising the following steps: comprises mixing rhizoma Ligustici Chuanxiong, ramulus Cinnamomi, fructus Aurantii, Olibanum, radix astragali, sanguis Draxonis, radix Paeoniae Rubra, Eupolyphaga Seu Steleophaga, fructus Perillae, Carthami flos, Myrrha, herba Lycopi, Curcumae rhizoma, Alismatis rhizoma, radix Puerariae, semen Ricini, Concha Haliotidis, Eucommiae cortex, Prunellae Spica, folium et ramulus Clerodendri Trichotomi, Siegesbeckiae herba, folium Mori, cortex Mori, herba Taxilli, flos Chrysanthemi Indici, Raphani semen, fructus Tribuli, fructus Vitics Simplicifoliae, semen Phaseoli, radix rehmanniae, radix Ophiopogonis, Poria, rhizoma Dioscoreae, cortex moutan, Achyranthis radix, herba plantaginis, Saviae Miltiorrhizae radix, ramulus Uncariae cum uncis, Lumbricus, exocarpium Persicae, radix et rhizoma Rhei, fructus crataegi, semen Cassiae, semen Sojae Atricolor, semen Ziziphi Spinosae, fructus Schisandrae chinensis, radix Concha Ostreae and Notoginseng radix in proportion, pulverizing, and making into desired dosage form.
7. The method of claim 4, wherein: the dosage forms include tablet, capsule, granule, powder, dripping pill, decoction and medicated tea.
8. The method of claim 7, wherein: when the preparation is tablets, capsules, granules, powder, dropping pills or pills, ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beeltle, perilla fruit, safflower, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, mulberry bark, loranthus parasiticus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, red bean, radix rehmanniae, radix ophiopogonis, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria, earthworm, peach red, rheum officinale, raw hawthorn, semen cassiae, black bean, spina date seed, schisandra chinensis, raw hemsleya japonica and pseudo-ginseng are mixed, crushed, added with water in an amount of 4-8 times of the weight of the total raw materials, heated and extracted for 2-3 times or added with alcohol in an amount of 4-8 times of the total weight of the total materials, extracted by reflux for 2-3 times, each time for 2-3 hours, filtering, mixing filtrates, concentrating under reduced pressure to obtain dry extract, pulverizing into powder, adding pharmaceutically conventional adjuvants, and making into desired dosage form.
9. The method of claim 7, wherein: when the preparation is a decoction, the ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus mongholicus, dragon's blood, red paeony root, ground beetle, perilla fruit, safflower carthamus, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, white mulberry root-bark, loranthus parasiticus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, phaseolus calcaratus, dried rehmannia root, radix ophiopogonis, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria, peach red, rheum officinale, raw hawthorn, semen cassiae, black soya bean, spina date seed, schisandra chinensis, raw oyster and pseudo-ginseng are mixed in proportion, crushed, added for decoction for 1-3 hours, and decoction liquid is taken to prepare the decoction.
10. The method of claim 7, wherein: when the preparation is a tea, ligusticum wallichii, cassia twig, fructus aurantii, frankincense, astragalus, dragon's blood, red paeony root, ground beetle, perilla fruit, safflower, myrrh, herba lycopi, curcuma zedoary, rhizoma alismatis, kudzu, castor bean, raw abalone shell, eucommia bark, selfheal, harlequin glorybower leaf, herba siegesbeckiae, mulberry leaf, white mulberry root bark, loranthus parasiticus, wild chrysanthemum flower, radish seed, tribulus terrestris, fructus viticis, phaseolus calcaratus, dried rehmannia root, radix ophiopogonis, poria with hostwood, yam, cortex moutan, radix achyranthis bidentatae, plantain herb, salvia miltiorrhiza, uncaria, earthworm, peach red, rheum officinale, raw hawthorn, cassia seed, black bean, spina date seed, schisandra chinensis, raw oyster shell and pseudo-ginseng are cleaned, dried at 30-60 ℃, mixed according to a proportion, crushed, sterilized and disinfected, and packed into a tea bag for making tea.
CN202210244635.0A 2022-03-14 2022-03-14 Traditional Chinese medicine composition for treating hypertension Withdrawn CN114588238A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125632A (en) * 2010-10-18 2011-07-20 吴肖慧 Chinese medicinal healthy tea for preventing and treating hypertension
CN106138514A (en) * 2016-08-02 2016-11-23 山东中医药大学附属医院 A kind of Chinese medicine composition treating intermingled phlegm and blood stasis type hypertension and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125632A (en) * 2010-10-18 2011-07-20 吴肖慧 Chinese medicinal healthy tea for preventing and treating hypertension
CN106138514A (en) * 2016-08-02 2016-11-23 山东中医药大学附属医院 A kind of Chinese medicine composition treating intermingled phlegm and blood stasis type hypertension and preparation method thereof

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张仁德: "治高血压病30方", 《致富之友》 *

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