CN114588055B - Stable bicontinuous phase cleansing oil and preparation method and application thereof - Google Patents
Stable bicontinuous phase cleansing oil and preparation method and application thereof Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 150000001875 compounds Chemical class 0.000 claims abstract description 42
- 239000004094 surface-active agent Substances 0.000 claims abstract description 17
- 229920005862 polyol Polymers 0.000 claims abstract description 14
- 150000003077 polyols Chemical class 0.000 claims abstract description 14
- 239000008139 complexing agent Substances 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 239000002904 solvent Substances 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 6
- 230000008569 process Effects 0.000 claims abstract description 5
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 claims description 20
- 239000002736 nonionic surfactant Substances 0.000 claims description 20
- 239000003945 anionic surfactant Substances 0.000 claims description 19
- -1 cetyl alcohol ethylhexyl ester Chemical class 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical group CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 claims description 12
- JDRSMPFHFNXQRB-CMTNHCDUSA-N Decyl beta-D-threo-hexopyranoside Chemical compound CCCCCCCCCCO[C@@H]1O[C@H](CO)C(O)[C@H](O)C1O JDRSMPFHFNXQRB-CMTNHCDUSA-N 0.000 claims description 12
- 229940073499 decyl glucoside Drugs 0.000 claims description 12
- ASKIVFGGGGIGKH-UHFFFAOYSA-N isostearic acid monoglyceride Natural products CC(C)CCCCCCCCCCCCCCC(=O)OCC(O)CO ASKIVFGGGGIGKH-UHFFFAOYSA-N 0.000 claims description 12
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 claims description 10
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 10
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 10
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 10
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 claims description 10
- 239000000600 sorbitol Substances 0.000 claims description 10
- 229960000541 cetyl alcohol Drugs 0.000 claims description 8
- BXWNKGSJHAJOGX-UHFFFAOYSA-N n-hexadecyl alcohol Natural products CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 8
- RRQYJINTUHWNHW-UHFFFAOYSA-N 1-ethoxy-2-(2-ethoxyethoxy)ethane Chemical compound CCOCCOCCOCC RRQYJINTUHWNHW-UHFFFAOYSA-N 0.000 claims description 6
- 229940019778 diethylene glycol diethyl ether Drugs 0.000 claims description 6
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical group OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 5
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 claims description 5
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical group [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 229960005323 phenoxyethanol Drugs 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000004902 Softening Agent Substances 0.000 claims description 4
- 239000000022 bacteriostatic agent Substances 0.000 claims description 4
- 150000003384 small molecules Chemical class 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 15
- 230000008021 deposition Effects 0.000 abstract description 3
- 230000006866 deterioration Effects 0.000 abstract description 2
- 230000003020 moisturizing effect Effects 0.000 abstract description 2
- 230000001953 sensory effect Effects 0.000 abstract description 2
- 230000000638 stimulation Effects 0.000 abstract description 2
- 239000003599 detergent Substances 0.000 abstract 1
- 239000003921 oil Substances 0.000 description 34
- 235000019198 oils Nutrition 0.000 description 34
- 239000012071 phase Substances 0.000 description 25
- 238000012360 testing method Methods 0.000 description 12
- 238000004140 cleaning Methods 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 8
- 239000002537 cosmetic Substances 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- FKIQSOGFDBALHA-UHFFFAOYSA-L aluminum trimagnesium potassium dioxido(oxo)silane oxygen(2-) difluoride Chemical compound [O--].[F-].[F-].[Mg++].[Mg++].[Mg++].[Al+3].[K+].[O-][Si]([O-])=O.[O-][Si]([O-])=O.[O-][Si]([O-])=O FKIQSOGFDBALHA-UHFFFAOYSA-L 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- 239000003974 emollient agent Substances 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 229940049918 linoleate Drugs 0.000 description 2
- 239000010445 mica Substances 0.000 description 2
- 229910052618 mica group Inorganic materials 0.000 description 2
- 238000011056 performance test Methods 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- QHZLMUACJMDIAE-UHFFFAOYSA-N 1-monopalmitoylglycerol Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(O)CO QHZLMUACJMDIAE-UHFFFAOYSA-N 0.000 description 1
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 1
- WAYINTBTZWQNSN-UHFFFAOYSA-N 11-methyldodecyl 3,5,5-trimethylhexanoate Chemical compound CC(C)CCCCCCCCCCOC(=O)CC(C)CC(C)(C)C WAYINTBTZWQNSN-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-M 9-cis,12-cis-Octadecadienoate Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O OYHQOLUKZRVURQ-HZJYTTRNSA-M 0.000 description 1
- 208000007848 Alcoholism Diseases 0.000 description 1
- 235000015655 Crocus sativus Nutrition 0.000 description 1
- 244000124209 Crocus sativus Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920001214 Polysorbate 60 Polymers 0.000 description 1
- 208000028017 Psychotic disease Diseases 0.000 description 1
- 239000004147 Sorbitan trioleate Substances 0.000 description 1
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 201000007930 alcohol dependence Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- PXGZQGDTEZPERC-UHFFFAOYSA-L cyclohexane-1,4-dicarboxylate Chemical compound [O-]C(=O)C1CCC(C([O-])=O)CC1 PXGZQGDTEZPERC-UHFFFAOYSA-L 0.000 description 1
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 1
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- ARIWANIATODDMH-UHFFFAOYSA-N rac-1-monolauroylglycerol Chemical compound CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 description 1
- DCBSHORRWZKAKO-UHFFFAOYSA-N rac-1-monomyristoylglycerol Chemical compound CCCCCCCCCCCCCC(=O)OCC(O)CO DCBSHORRWZKAKO-UHFFFAOYSA-N 0.000 description 1
- 229940066675 ricinoleate Drugs 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 235000019337 sorbitan trioleate Nutrition 0.000 description 1
- 229960000391 sorbitan trioleate Drugs 0.000 description 1
- 150000003871 sulfonates Chemical class 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- XOLBLPGZBRYERU-UHFFFAOYSA-N tin dioxide Chemical compound O=[Sn]=O XOLBLPGZBRYERU-UHFFFAOYSA-N 0.000 description 1
- 229910001887 tin oxide Inorganic materials 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/14—Preparations for removing make-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the field of IPC A61K8/00, in particular to stable bicontinuous phase cleansing oil and a preparation method and application thereof. The raw materials comprise, by weight: 10-36 parts of surfactant, 20-48 parts of softener, 20-32 parts of polyol, 0.01-0.2 part of complexing agent, 0.1-5 parts of amphiphilic compound, 0.1-5 parts of bacteriostat and 0-60 parts of solvent. The invention has the following advantages: the cleansing agent can prevent secondary deposition of makeup, quickly dissolve various makeup products, and has stronger cleansing power and remarkable makeup removal effect compared with the traditional makeup removal oil products; the temperature resistance of the cleansing oil is improved, layering and deterioration phenomena are not easy to occur, and the cleansing oil can be stored for a long time; the skin care product has the advantages of fresh and cool texture, no greasiness, mild and clean skin, obvious moisturizing and nourishing effects on the skin, no stimulation to the skin in the use process, moist and tender skin after use, no dryness, tightness and comfortable sensory experience.
Description
Technical Field
The invention relates to the field of IPC A61K8/00, in particular to stable bicontinuous phase cleansing oil and a preparation method and application thereof.
Background
Bicontinuous systems are generally composed of oils, polyols, water, and nonionic surfactants. Compared with the common cleansing oil product, the double continuous phase cleansing oil product has more fresh use feeling, can be used by wet hands, has low greasy feeling after cleaning, and does not need to use a cleansing product for secondary cleaning after use. However, the oil content is lower than that of the makeup removing oil product, so that the double continuous phase makeup removing product is easy to be deposited on the skin for the second time after the makeup is dissolved and dispersed when the W/0 type cosmetics are removed, and cannot remove the clean phenomenon, so that the makeup removing force is weaker than that of the makeup removing oil product, and no makeup removing oil product is popular in the market.
Chinese patent CN202011157624.6 discloses a bicontinuous phase cleansing oil and its preparation method, 75-95% of cosmetic matrix and 5-25% of surfactant are mixed, and by means of the combined action of natural vegetable oil and alkane, ester and ether grease, good cleansing effect is obtained; however, the natural vegetable oil is unstable, is easy to delaminate and change color, and is difficult to store for a long time. Chinese patent CN202110158516.9 discloses a formula and a preparation method of makeup removing essence, wherein polyacrylate crosslinked polymer-6 composition, PEG-glyceride substance, mica composition, and crocus sativus extract composition are adopted to act, so that water-based makeup removing essence with strong permeability is obtained; however, the synthetic fluorophlogopite, CI 77891, tin oxide and mica composition adopted by the synthetic fluorophlogopite and the synthetic fluorophlogopite have extremely high separation tendency from a liquid phase system, and the synthetic fluorophlogopite cannot be stored for a long time.
Under the background, the double continuous phase cleansing oil with strong cleansing effect, wide application range and strong stability is explored and becomes a problem to be solved in the field.
Disclosure of Invention
The stable bicontinuous phase cleansing oil solves the problems that in the prior art, cleansing products are incomplete in cleansing, skin is easy to tighten and dry after use, and the product stability is poor, and the bicontinuous phase cleansing oil is strong in cleansing effect, wide in application range and strong in stability.
The invention provides stable bicontinuous phase cleansing oil, which comprises the following raw materials in parts by weight: 10-36 parts of surfactant, 20-48 parts of softener, 20-32 parts of polyol, 0.01-0.2 part of complexing agent, 0.1-5 parts of amphiphilic compound, 0.1-5 parts of bacteriostat and 0-60 parts of solvent.
Further preferably, the raw materials comprise, in parts by weight: 25-32 parts of surfactant, 30-40 parts of softener, 25-30 parts of polyol, 0.05-0.12 part of complexing agent, 0.5-3 parts of amphiphilic compound, 0.1-1 part of bacteriostat and 2-20 parts of solvent.
In one placeIn some preferred embodiments, the amphiphilic compound has a molecular weight of 100 to 440, and the amphiphilic compound has a molecular structure of at least 1A unit.
In some preferred embodiments, the surfactant comprises at least 2 of a nonionic surfactant, an anionic surfactant, and a zwitterionic surfactant.
Further preferably, the surfactant includes a nonionic surfactant and an anionic surfactant; the weight ratio of the nonionic surfactant to the anionic surfactant is (15-32): (1-3); preferably 28.5:1.5.
the invention discovers that the amphiphilic compound with a specific structure is applied to a bicontinuous phase system in a certain proportion, so that the secondary deposition of makeup can be prevented, and the obtained bicontinuous phase makeup removing oil has stronger makeup removing force than the traditional makeup removing oil product. The synergistic effect can be exerted by adopting the combined action of a specific amount of nonionic surfactant and anionic surfactant, and the marks of the make-up can be effectively removed. However, the addition of the surfactant has the disadvantage of being sensitive to temperature change, turbidity easily occurs after the temperature is raised, and stable cleaning capability is difficult to maintain.
In some preferred embodiments, the nonionic surfactant comprises one or more of PEG glycerol isostearate, decyl glucoside, 2, 3-dihydroxypropyl stearate, 2, 3-dihydroxypropyl ricinoleate, 2, 3-dihydroxypropyl palmitate, 2, 3-dihydroxypropyl laurate, 2, 3-dihydroxypropyl myristate, 2, 3-hydroxypropyl linoleate, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan monostearate, distearyl dimerized linoleate, isotridecyl isononanoate, decyl polyoxyethylene ether.
In some preferred embodiments, the anionic surfactant is a combination of one or more of branched fatty acids, sulfonates, sulfate salts.
Further preferably, the nonionic surfactant is PEG-8 glycerol isostearate and decyl glucoside, and the weight ratio of PEG-8 glycerol isostearate to decyl glucoside is (40-65): 1, a step of; preferably 56:1.
further preferably, the anionic surfactant is isostearic acid.
The invention further discovers that PEG-8 glycerol isostearate and decyl glucoside are adopted as nonionic surfactants, isostearic acid is adopted as an anionic surfactant, and the mixture is compounded in a specific weight ratio, so that a stable phase stable structure can be formed with amphiphilic compounds, emollients and the like, and the temperature resistance of the bicontinuous phase cleansing oil is greatly improved.
In some preferred embodiments, the emollient comprises a combination of one or more of fatty acid esters, fatty alcohols, C10-20 saturated alkanes, triglycerides and derivatives thereof, animal fats and oils.
Further preferably, the emollient is cetyl ethylhexyl ester and isohexadecane, the weight ratio of cetyl ethylhexyl ester and isohexadecane being (4-8): 1, a step of; preferably 6:1.
examples of complexing agents include, but are not limited to, EDTA 2Na.
In some preferred embodiments, the polyol comprises one or more of sorbitol, dipropylene glycol, glycerol, butylene glycol, polyethylene glycol.
Further preferably, the polyol comprises sorbitol and dipropylene glycol in a weight ratio of (3-6.4): (7-12), preferably 5:9.
in some preferred embodiments, the amphiphilic compound comprises a macromolecular amphiphilic compound and a small molecular amphiphilic compound in a weight ratio of (1-5): 1, a step of; preferably 3:1.
preferably, the molecular weight of the macromolecular amphiphilic compound is 300-440, and bis-diethoxydiglycol cyclohexane 1, 4-dicarboxylate is exemplified, and the molecular weight is 405.
Preferably, the molecular weight of the small molecule amphiphilic compound is 100-240, which can be exemplified by diethylene glycol diethyl ether, and the molecular weight is 134; ethylhexyl glycerol, molecular weight 204.
The invention further discovers that various oil-soluble substances can be rapidly dissolved by adopting the combined action of the macromolecular amphiphilic compound and the micromolecular amphiphilic compound, O/W type and W/0 type makeup removing products can be effectively removed by adopting the double-continuous microemulsified system makeup removing oil, the makeup removing effect is obvious (as shown in figures 1 and 2), meanwhile, the texture of the double-continuous phase makeup removing oil is fresh and not greasy, the skin is mild and not stimulated in the use process, the skin is not uncomfortable such as tight, dry and astringent after the use, and the cleansing and nourishing are integrated.
Examples of complexing agents include, but are not limited to, phenoxyethanol.
The solvent is water, more preferably deionized water.
In some preferred embodiments, the weight ratio of surfactant, emollient and amphiphilic compound is (12-16): (15-20): 1.
the invention provides a preparation method of stable bicontinuous phase cleansing oil, which comprises the steps of mixing raw materials according to formula amount, heating to 35-45 ℃, and stirring for 20-60 min.
In a third aspect, the present invention provides the use of a stable bicontinuous phase cleansing oil suitable for the removal of lipsticks, eyeliners, mascaras.
The beneficial effects are that:
the invention provides stable bicontinuous phase cleansing oil, which has the following advantages:
(1) The amphipathic compound with a specific structure is compounded in a bicontinuous phase system, so that secondary deposition of makeup can be prevented, various makeup products can be quickly dissolved, and compared with the traditional makeup removal oil products, the cleansing effect is stronger, and the makeup removal effect is obvious;
(2) The stability of the cleansing oil is improved by matching with a specific surfactant, the temperature resistance of the cleansing oil is improved, layering and deterioration phenomena are not easy to occur, and the cleansing oil can be stored for a long time;
(3) The invention has fresh and cool texture, is not greasy, can gently clean skin, has obvious moisturizing and nourishing effects on the skin, has no stimulation on the skin in the use process, and has the advantages of moist and tender skin, no dryness, tightness and comfortable sensory experience after the use.
Drawings
FIG. 1A is a comparative view of makeup removal effect of test person A using example 1;
FIG. 2 is a comparative view of makeup removal effect of test person B using example 2;
FIG. 3 is a comparative graph of makeup removal effect of the test person C using comparative example 1;
note that: in the drawings, the left side is before makeup removal, and the right side is after makeup removal; the makeup applied from top to bottom is a makeup product 1,3,2.
Detailed Description
Example 1.
The embodiment provides stable bicontinuous phase cleansing oil which comprises the following raw materials in parts by weight: 30 parts of surfactant, 35 parts of softener, 28 parts of polyol, 0.1 part of complexing agent, 2 parts of amphiphilic compound, 0.5 part of bacteriostat and 4.4 parts of solvent.
The surfactant includes nonionic surfactant and anionic surfactant; the weight ratio of nonionic surfactant to anionic surfactant was 28.5:1.5.
the nonionic surfactant is PEG-8 glycerol isostearate and decyl glucoside, and the weight ratio of the PEG-8 glycerol isostearate to the decyl glucoside is 56:1.
the anionic surfactant is isostearic acid.
The softening agent is cetyl alcohol ethylhexyl ester and isohexadecane, and the weight ratio of the cetyl alcohol ethylhexyl ester to the isohexadecane is 6:1.
the complexing agent is EDTA 2Na.
The polyol comprises sorbitol and dipropylene glycol, wherein the weight ratio of the sorbitol to the dipropylene glycol is 5:9.
the amphiphilic compound comprises a macromolecular amphiphilic compound and a small-molecular amphiphilic compound, wherein the weight ratio of the macromolecular amphiphilic compound to the small-molecular amphiphilic compound is 3:1.
the macromolecular amphiphilic compound is specifically bis-diethoxydiglycol cyclohexane 1, 4-dicarboxylic acid ester, the molecular weight is 405, and the CAS number is 922165-31-9.
The small molecule amphiphilic compound is specifically diethylene glycol diethyl ether, and the molecular weight is 134.
The bacteriostatic agent is phenoxyethanol.
The solvent is water, in particular deionized water.
The preparation method of the bicontinuous phase cleansing oil comprises the steps of mixing raw materials according to the formula amount, heating to 40 ℃, and stirring for 30 min.
Example 2.
The embodiment provides stable bicontinuous phase cleansing oil which comprises the following raw materials in parts by weight: 30 parts of surfactant, 35 parts of softener, 28 parts of polyol, 0.1 part of complexing agent, 3 parts of amphiphilic compound, 0.5 part of bacteriostat and 3.4 parts of solvent.
The surfactant includes nonionic surfactant and anionic surfactant; the weight ratio of nonionic surfactant to anionic surfactant was 28.5:1.5.
the nonionic surfactant is PEG-8 glycerol isostearate and decyl glucoside, and the weight ratio of the PEG-8 glycerol isostearate to the decyl glucoside is 56:1.
the anionic surfactant is isostearic acid.
The softening agent is cetyl alcohol ethylhexyl ester and isohexadecane, and the weight ratio of the cetyl alcohol ethylhexyl ester to the isohexadecane is 6:1.
the complexing agent is EDTA 2Na.
The polyol comprises sorbitol and dipropylene glycol, wherein the weight ratio of the sorbitol to the dipropylene glycol is 5:9.
the amphiphilic compound comprises a macromolecular amphiphilic compound and a small-molecular amphiphilic compound, wherein the weight ratio of the macromolecular amphiphilic compound to the small-molecular amphiphilic compound is 4:3.
the macromolecular amphiphilic compound is specifically bis-diethoxydiglycol cyclohexane 1, 4-dicarboxylic acid ester, and the molecular weight is 405.
The small molecule amphiphilic compound is specifically diethylene glycol diethyl ether and ethylhexyl glycerol, and the molecular weight of the diethylene glycol diethyl ether is 134; the molecular weight of ethylhexyl glycerol is 204.
The bacteriostatic agent is phenoxyethanol.
The solvent is water, in particular deionized water.
The preparation method of the bicontinuous phase cleansing oil comprises the steps of mixing raw materials according to the formula amount, heating to 40 ℃, and stirring for 30 min.
Comparative example 1.
The comparative example provides a stable bicontinuous phase cleansing oil, which comprises the following raw materials in parts by weight: 30 parts of surfactant, 35 parts of softener, 28 parts of polyol, 0.1 part of complexing agent, 0.5 part of bacteriostat and 6.4 parts of solvent.
The surfactant includes nonionic surfactant and anionic surfactant; the weight ratio of nonionic surfactant to anionic surfactant was 28.5:1.5.
the nonionic surfactant is PEG-8 glycerol isostearate and decyl glucoside, and the weight ratio of the PEG-8 glycerol isostearate to the decyl glucoside is 56:1.
the anionic surfactant is isostearic acid.
The softening agent is cetyl alcohol ethylhexyl ester and isohexadecane, and the weight ratio of the cetyl alcohol ethylhexyl ester to the isohexadecane is 6:1.
the complexing agent is EDTA 2Na.
The polyol comprises sorbitol and dipropylene glycol, wherein the weight ratio of the sorbitol to the dipropylene glycol is 5:9.
the bacteriostatic agent is phenoxyethanol.
The solvent is water, in particular deionized water.
The preparation method of the bicontinuous phase cleansing oil comprises the steps of mixing raw materials according to the formula amount, heating to 40 ℃, and stirring for 30 min.
Performance test method
1. Cleansing effect
3 female testers (A, B, C) were screened and the makeup removal effect test was performed on examples 1, 2 and comparative example 1, respectively. The test method is specifically that,
(1) Firstly, cleaning the arm by a tester, and drawing 3 circular areas with the diameter of 3cm on the arm after the arm is wiped dry, wherein the numbers are A1-A3, B1-B3 and C1-C3; measuring L (brightness), a (red/green value) and b (blue/Huang Zhi) of each area of skin before applying the makeup product by using a spectrophotometer, and calculating delta E (before applying);
(2) Applying make-up product 1 (eyeliner) to A1, B1, C1; make-up product 2 (lipstick) is applied on A2, B2, C2, make-up product 3 (mascara) is applied on A3, B3, C3 (application amount is 1mL/9 cm) 2 Massaging for one minute after painting); standing for 30min to shape the color cosmetics, testing the L, a and b values of each area of the skin after the color cosmetics are applied, and calculating delta E (after the color cosmetics are applied);
(3) Respectively taking 1mL of examples 1 and 2, coating comparative example 1 on the test areas on arms A, B and C, then washing cleanly with clear water, lightly wiping water with paper towels, testing the L, a and B values of each area of skin after makeup removal and cleaning, and calculating delta E (after cleaning);
the calculation formula of deltae and cleaning force C is as follows:
the female tester satisfied the following conditions: (1) non-pregnant or lactating women; (2) non-psychotic, alcoholism, drug addicts; (3) patients without systemic disease or severe skin disease; (4) History of severe allergy (including cosmetics and others)
Test equipment: the testing temperature of the alice 64-spectrophotometer and the CK moisture testing probe is 20+/-2 ℃; the test humidity is 45+/-5%; the effect is recorded by simultaneous photographing during the test, see fig. 1-3.
Remarks: the makeup applied from top to bottom is a makeup product 1 (eyeliner) Qishimei superfine waterproof eyeliner, a makeup product 3 (mascara) Qishimei third generation waterproof mascara, and a makeup product 2 (lipstick) perfect diary hazy dream matte lip glaze.
2. Stability of
The samples of examples 1 and 2 were placed at-18℃and 5℃for 12 weeks, respectively, and the samples were taken out without defects such as delamination, discoloration, and precipitation.
Performance test data
Table 1.
As can be seen from table 1 and fig. 1-3, the bicontinuous cleansing oil added with the specific amphiphilic compound has a strong cleansing ability, and is effective in removing marks on the skin of eyeliners, mascaras, and particularly lipsticks. Therefore, the amphiphilic compound with matched molecular weight is added into the bicontinuous phase makeup removing system, so that the secondary adhesion of makeup on skin in the makeup removing process is reduced, and the cleaning force is obviously improved.
Claims (3)
1. The stable bicontinuous phase cleansing oil is characterized by comprising the following raw materials in parts by weight: 30 parts of surfactant, 35 parts of softener, 28 parts of polyol, 0.1 part of complexing agent, 3 parts of amphiphilic compound, 0.5 part of bacteriostat and 3.4 parts of solvent;
the surfactant includes nonionic surfactant and anionic surfactant; the weight ratio of nonionic surfactant to anionic surfactant was 28.5:1.5;
the nonionic surfactant is PEG-8 glycerol isostearate and decyl glucoside, and the weight ratio of the PEG-8 glycerol isostearate to the decyl glucoside is 56:1, a step of;
the anionic surfactant is isostearic acid;
the softening agent is cetyl alcohol ethylhexyl ester and isohexadecane, and the weight ratio of the cetyl alcohol ethylhexyl ester to the isohexadecane is 6:1, a step of;
the complexing agent is EDTA 2Na;
the polyol comprises sorbitol and dipropylene glycol, wherein the weight ratio of the sorbitol to the dipropylene glycol is 5:9, a step of performing the process;
the amphiphilic compound comprises a macromolecular amphiphilic compound and a small-molecular amphiphilic compound, wherein the weight ratio of the macromolecular amphiphilic compound to the small-molecular amphiphilic compound is 4:3, a step of;
the macromolecular amphiphilic compound is specifically bis-diethoxy diglycol cyclohexane 1, 4-dicarboxylic acid ester, and the molecular weight is 405;
the small molecule amphiphilic compound is specifically diethylene glycol diethyl ether and ethylhexyl glycerol, and the molecular weight of the diethylene glycol diethyl ether is 134; the molecular weight of the ethylhexyl glycerol is 204;
the bacteriostatic agent is phenoxyethanol;
the solvent is water.
2. The preparation method of the stable bicontinuous phase cleansing oil according to claim 1, which is characterized in that the bicontinuous phase cleansing oil is prepared by mixing raw materials according to formula amount, heating to 40 ℃, and stirring for 30 min.
3. Use of a stable bicontinuous phase makeup remover according to any of claims 1-2, characterized in that it is applied to the removal of lipsticks, eyeliners, mascaras.
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