CN114558098A - Preparation method and application of far infrared physiotherapy patch - Google Patents
Preparation method and application of far infrared physiotherapy patch Download PDFInfo
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- CN114558098A CN114558098A CN202210284774.6A CN202210284774A CN114558098A CN 114558098 A CN114558098 A CN 114558098A CN 202210284774 A CN202210284774 A CN 202210284774A CN 114558098 A CN114558098 A CN 114558098A
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- infrared physiotherapy
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Abstract
The invention discloses a preparation method and application of a far infrared physiotherapy plaster. The invention is prepared by mixing 25-50% of traditional Chinese medicine powder, 10-30% of ceramic powder and 20-45% of acrylic pressure-sensitive adhesive, coating the mixture on non-woven fabric, drying, protecting adhesive surface with silicone paper, and cutting. The formula of the invention contains the traditional Chinese medicines with the functions of promoting blood circulation and resisting inflammation, can promote local blood circulation, strengthen the supply of local oxygen and nutrient substances, effectively eliminate local metabolites such as lactic acid, carbon dioxide and the like, relieve the stimulation of local inflammation pathogenic factors, and relieve the symptoms of muscle spasm, local pain and tight and hard neck, shoulder and joints. Through two-in-one external application therapies of perfect fusion of penetration repair such as far infrared thermotherapy, external application of Chinese herbal medicines and the like, the skin is penetrated to generate the effects of diminishing inflammation, relieving pain, promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals, inducing resuscitation and penetrating bones, dispelling wind and removing cold and the like. The far infrared physiotherapy plaster prepared by the invention has exact curative effect on adjuvant therapy of cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, osteoarthritis and soft tissue injury (non-acute stage).
Description
Technical Field
The invention relates to the field of preparation of physical therapy patches of medical instruments, in particular to a preparation method and application of a far infrared physical therapy patch.
Background
Along with the change of life style and the increase of life pressure of people, more and more people suffer from scapulohumeral periarthritis, cervical spondylosis, lumbar disc herniation and other diseases. The disease course is longer because scapulohumeral periarthritis, cervical spondylosis, lumbar disc herniation, osteoarthritis and soft tissue injury (non-acute stage) belong to chronic diseases. After surgery or acupuncture and moxibustion and other treatments, if auxiliary treatment is not performed, the disease condition is easy to repeat, and auxiliary treatment means of dredging the channels and collaterals, increasing local blood circulation and promoting blood circulation to remove blood stasis are needed after the surgery or acupuncture and moxibustion treatment.
The far infrared ceramic powder can absorb the self-radiated energy of a human body and directly emit far infrared light waves, when the frequency is consistent with the movement frequency of water molecules among cell molecules and atoms in the body, the resonance effect can be caused, the temperature of the deep part of subcutaneous tissue is raised, the generated heat effect activates the water molecules, the water molecules are in a high-energy state, the synthesis of biological enzymes required by the human body is accelerated, and meanwhile, the biological molecules such as protein and the like are activated, so that the immunity of the organism and the tissue regeneration capability of biological cells are enhanced, the characteristics of improving microcirculation, enhancing the activity of the organism cells and strengthening metabolism can effectively promote the blood circulation, thereby activating the cell tissues and improving the metabolism function, and the treatment purposes of rapidly relieving pain and preventing pain recurrence are achieved.
The traditional Chinese medicine has the advantage of small side effect in the treatment of osteoarthritis and various chronic joint diseases, and compared with a single traditional Chinese medicine, the traditional Chinese medicine formula can exert the effects of multiple ways and multiple targets. The medicine applied on body surface can stimulate nerve ending, dilate blood vessel, promote blood circulation, improve peripheral tissue nutrition, and achieve the purpose of detumescence, anti-inflammation and analgesia. Meanwhile, the medicine permeates to subcutaneous tissues at the affected part through skin and generates higher medicine concentration locally, thereby playing stronger pharmacological action.
The two-in-one external application therapy perfectly fusing the penetration and restoration, such as far infrared thermotherapy, external application of Chinese herbal medicines and the like, can penetrate through the skin to generate the effects of diminishing inflammation, relieving pain, promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals, inducing resuscitation and penetrating bones, dispelling wind and removing cold and the like. Therefore, the far infrared physiotherapy plaster added with the traditional Chinese medicines can be used as an ideal auxiliary means for scapulohumeral periarthritis, cervical spondylosis, lumbar disc herniation, osteoarthritis and soft tissue injury (in non-acute stage).
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a preparation method of a far infrared physiotherapy plaster.
The invention also aims to provide the application of the far infrared physiotherapy plaster in the adjuvant therapy of cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, osteoarthritis and soft tissue injury (non-acute stage).
In order to achieve the purpose, the invention is realized by the following technical scheme:
a preparation method of a far infrared physiotherapy patch comprises the following steps:
(1) adding the traditional Chinese medicine powder and the ceramic powder into the acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and can not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to obtain a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physiotherapy plaster.
Preferably, the preferred mass percentages of the traditional Chinese medicine powder, the ceramic powder and the acrylic pressure-sensitive adhesive are as follows: 25-50% of traditional Chinese medicine powder, 10-30% of ceramic powder and 20-45% of acrylic pressure-sensitive adhesive.
Preferably, the traditional Chinese medicine powder comprises the following components in percentage by mass: 15-30% of obscured homalomena rhizome, 10-30% of diverse wormwood herb, 10-20% of turmeric, 10-20% of Chinese starjasmine stem, 10-15% of garden balsam stem and 10-15% of catechu.
Preferably, the ceramic powder is far infrared ceramic powder with the fineness of more than 2000 meshes.
Preferably, the traditional Chinese medicine powder is sieved by a 100-mesh sieve.
An application of far infrared physiotherapy patch in adjuvant treatment of cervical spondylosis, scapulohumeral periarthritis, lumbar intervertebral disc prolapse, osteoarthritis, and soft tissue injury (non-acute stage).
Compared with the prior art, the invention has the following beneficial effects:
the far infrared paste adopts modern nanometer material-far infrared ceramic powder, which is a perfect combination of optics, thermotics and medical technology. When the skin absorbs heat energy, it can release 5-15 μm of far infrared light, which is in accordance with the vibration frequency of human cell atoms and water molecules, and can activate human tissue cells, rapidly penetrate skin, act on affected part, and block the synthesis of pain-relieving medium. Clinical cases prove that the patch can not only avoid toxic and side effects of internal medicine, but also overcome the difficulty of transdermal application of common external patches.
Qiannianjian recorded in Ben Cao gang mu Shi Yi (supplement to compendium of materia Medica), is bitter and pungent in flavor and warm in nature, so it is good for all ages. Has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles, activating collaterals, and strengthening tendons and bones, and can be used for treating waist and knee joint pain, difficulty in flexion and extension, traumatic injury, fracture and muscle injury, blood stasis and swelling pain or liver and kidney deficiency, foot atrophy and weakness, lower limb spasm and pain, and lower limb cold pain due to pathogenic wind-cold-dampness, and meridian obstruction. Pharmacological research shows that the compound has the functions of resisting inflammation, easing pain, resisting osteoporosis, resisting pathogenic microorganisms, resisting oxidation, resisting tumors and the like.
Herba Artemisiae Anomalae is prepared from herba Artemisiae Anomalae of Artemisia of Compositae by using whole plant of Strychnos as medicine. Also called as semen Panici Miliacei, June cream. Pungent and bitter in flavor and cool in nature, and is a good medicine for promoting blood circulation, removing blood stasis, relieving swelling and pain, clearing heat and removing dampness. It is pungent, bitter and purgative, cool, can clear heat, specially enter blood system, move and disperse, and has outstanding effect for treating blood-qi distention. Pharmacological research shows that diverse wormwood herb has the effects of resisting platelet aggregation, resisting thrombosis, resisting bacteria and resisting oxidation. In clinical application, it can be used for treating burn, scald, fracture, scleroderma, inflammation and shoulder injury.
Curcuma rhizome is dried rhizome of Curcuma of Zingiberaceae, is perennial herb, and can be used as both medicine and food. The Zhong Li in Tang Ben Cao records its pungent, bitter and warm nature as the middle ingredient. Has the functions of breaking blood and promoting qi circulation, and stimulating the menstrual flow and relieving pain. It is indicated for stabbing pain in chest and hypochondrium, amenorrhea, mass, pain in shoulder and arm due to wind-damp evils, swelling and pain due to traumatic injuries, etc. Curcuma rhizome has effects of reducing the expression and secretion of inflammatory cytokine, mediating various inflammatory signal pathways, and regulating inflammation-related cell function (such as macrophage), and has anti-inflammatory effect, and is suitable for scapulohumeral periarthritis, osteoarthritis, etc.
Trachelospermi caulis is recorded as the top grade product in Shen nong Ben Cao Jing, which has mild smell, bitter and warm property, has the effects of dispelling pathogenic wind, dredging collaterals, cooling blood and relieving swelling, and is mainly used for treating rheumatism, pyretic arthralgia, spasm of muscles and tendons, soreness of waist and knees, carbuncle and swelling and the like. Modern clinical application also widely applies to the treatment of rheumatoid arthritis, arthritis and other diseases with syndrome of wind-damp-heat. Modern pharmacological research considers that the effects of resisting inflammation, easing pain, inhibiting abnormal immunity and the like are the pharmacological basis of the traditional Chinese medicine for dispelling rheumatism.
Speranskia herb, recorded in Jiu Yao Ben Cao (materia Medica of saving wasteland), has the effects of dispelling wind and removing dampness, relaxing muscles and tendons, promoting blood circulation and relieving pain. Pharmacological research suggests that the traditional Chinese medicine has effects of resisting inflammation, resisting oxidation, inhibiting platelet aggregation, etc., and is mainly used for treating rheumatalgia, contracture of bones and muscles, cold-dampness beriberi and arthritis, etc.
Catechu, the main components catechin and epicatechin, produce anti-inflammatory effect by inhibiting COX and 5-LOX. Catechu is bitter and astringent in taste and slightly cold in nature, and has effects of promoting blood circulation, relieving pain, stopping bleeding, promoting granulation, astringing dampness, healing sore, clearing lung-heat and eliminating phlegm. Is mainly used for treating traumatic injury pain, traumatic hemorrhage, etc.
The far infrared physiotherapy plaster prepared by adding the traditional Chinese medicines has more remarkable effect than the physiotherapy plaster products on the market for auxiliary treatment of cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, osteoarthritis and soft tissue injury (in non-acute stage), has various components for promoting blood circulation and resisting inflammation, can relieve arthritis and pain degree of patients at multiple targets, and has the unique advantages of small side effect and easy transdermal absorption.
Drawings
FIG. 1 shows the VAS and CMS scores of different groups of scapulohumeral periarthritis
FIG. 2 VAS and CMS score comparison for different groups of cervical spondylosis and lumbar disc herniation
FIG. 3 is a comparison of VAS and Lequesne scores for osteoarthritis
FIG. 4 is a graph showing the comparison of the clinical effects of soft tissue injury (non-acute stage)
FIG. 5 is a comparison of the results of 20-minute writhing of mice
Detailed Description
The present invention is further described in detail below with reference to specific examples, which are provided for illustration only and are not intended to limit the scope of the present invention. The test methods used in the following examples are all conventional methods unless otherwise specified; the materials, reagents and the like used are, unless otherwise specified, commercially available reagents and materials.
Example 1
A preparation method of a far infrared physiotherapy patch comprises the following steps:
(1) adding 25% by mass of traditional Chinese medicine powder (the traditional Chinese medicine powder comprises 20% by mass of obscured homalomena rhizome, 20% by mass of diverse wormwood herb, 10% by mass of turmeric, 20% by mass of Chinese starjasmine stem, 15% by mass of garden balsam stem and 15% by mass of catechu) and 30% by mass of ceramic powder into 45% of acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and does not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to form a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physical therapy patch.
Example 2
A preparation method of a far infrared physiotherapy patch comprises the following steps:
(1) adding 30% by mass of traditional Chinese medicine powder (the traditional Chinese medicine powder comprises, by mass, 25% of obscured homalomena rhizome, 25% of diverse wormwood herb, 15% of turmeric, 15% of Chinese starjasmine stem, 10% of garden balsam stem and 10% of catechu) and 25% of ceramic powder into 45% of acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and does not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to form a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physical therapy patch.
Example 3
(1) Adding 35% by mass of traditional Chinese medicine powder (the traditional Chinese medicine powder comprises, by mass, 25% of obscured homalomena rhizome, 25% of diverse wormwood herb, 20% of turmeric, 10% of Chinese starjasmine stem, 10% of garden balsam stem and 10% of catechu) and 25% of ceramic powder into 40% of acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and does not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to form a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physical therapy patch.
Example 4
(1) Adding 40% by mass of traditional Chinese medicine powder (the traditional Chinese medicine powder comprises 20% by mass of obscured homalomena rhizome, 10% by mass of diverse wormwood herb, 20% by mass of turmeric, 20% by mass of Chinese starjasmine stem, 15% by mass of garden balsam stem and 15% by mass of catechu) and 25% by mass of ceramic powder into 35% of acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and can not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to form a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physical therapy patch.
Example 5
(1) Adding 45% by mass of traditional Chinese medicine powder (the traditional Chinese medicine powder comprises, by mass, 10% of obscured homalomena rhizome, 20% of diverse wormwood herb, 20% of turmeric, 20% of Chinese starjasmine stem, 15% of garden balsam stem and 15% of catechu) and 25% by mass of ceramic powder into 30% of acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and can not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to form a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physical therapy patch.
Example 6
(1) Adding 50% by mass of Chinese medicinal powder (comprising 30% of rhizoma homalomenae, 30% of herba Artemisiae Anomalae, 10% of Curcuma rhizome, 10% of caulis Trachelospermi, 10% of caulis et folium Gaultheriae Yunnanensis, and 10% of Catechu) and 25% of ceramic powder into 25% of acrylic pressure sensitive adhesive, and stirring to obtain viscous mixture with certain fluidity, so that the viscous mixture can be coated without flowing in backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to form a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physical therapy patch.
Example 7
(1) Adding 50% by mass of traditional Chinese medicine powder (the traditional Chinese medicine powder comprises 30% by mass of obscured homalomena rhizome, 25% by mass of diverse wormwood herb, 15% by mass of turmeric, 10% by mass of Chinese starjasmine stem, 10% by mass of garden balsam stem and 10% by mass of catechu) and 30% by mass of ceramic powder into 20% of acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and can not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to obtain a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physiotherapy plaster.
In order to confirm that the far infrared physiotherapy patch of the present invention has an exact therapeutic effect on adjuvant therapy of cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, osteoarthritis, and soft tissue injury (non-acute stage), the following clinical trials were performed using the far infrared physiotherapy patch prepared by the method of example 4:
test one: clinical efficacy test for scapulohumeral periarthritis
1. Experimental method
50 patients with scapulohumeral periarthritis were selected. 25 of the male patients and 25 of the female patients; age 45-57 years, mean 50.9 years; the course of the disease is 6-8 months, and the average (7 +/-0.8) month; the two groups have no significant difference (P >0.05) in disease conditions, age, disease course and the like, and have comparability.
Test groups: the far infrared physiotherapy patch prepared in example 3 is applied to the affected shoulder, and is replaced for 1 time in 12 hours, wherein 10 days are 1 treatment course, and three treatment courses are total. Control group: the Qizheng Xiaotong plaster is applied to the affected shoulder, and is replaced for 1 time in 12 hours, 10 days are 1 treatment course, and three treatment courses are total. Blank group: no treatment is carried out, and three treatment courses are carried out.
2. Observation index
(1) Degree of shoulder pain. The pain in the shoulder joints of patients in the blank group, the test group and the control group after three treatment courses were scored by VAS (visual analogue scoring). The pain degree is quantified to be 0-10 points, and the higher the score is, the stronger the pain degree is.
(2) Shoulder joint function. After three treatment courses, patients in the blank group, the test group and the control group are scored according to a shoulder joint Constant-Murley scoring scale (CMS) from 4 aspects of pain, muscle strength, joint function and joint activity, wherein the higher the score is, the better the joint function is represented.
3. Statistical analysis
SPSS21.0 statistical software is adopted for data processing, the measurement data is expressed by mean plus or minus standard deviation (x plus or minus s), t test is carried out, and P <0.05 is difference, which has statistical significance.
4. Therapeutic results
Three groups of patients were treated for three courses of treatment, and the statistical results of the visits were as follows:
TABLE 1 VAS, CMS score comparison (x + -s, points) for different groups of scapulohumeral periarthritis
Note: p <0.05 compared to blank group
Figure 1 shows the VAS and CMS score comparison results of different scapulohumeral periarthritis groups
And (2) test II: clinical efficacy test for lumbar disc herniation and cervical spondylosis
1. Experimental methods
50 patients with lumbar disc herniation and 50 patients with cervical spondylosis were selected. 25 cases of male patients and 25 cases of female patients respectively; age 45-57 years, mean 50.9 years; the course of the disease is 6-8 months, and the average (7 +/-0.8) month; the two groups have no significant difference (P >0.05) in disease conditions, age, disease course and the like, and have comparability.
Test groups: the far infrared physiotherapy patch prepared in the embodiment 3 is applied to an affected part, and is replaced for 1 time in 12 hours, 10 days are 1 treatment course, and three treatment courses are total. Control group: the QIZHENGXIAOTONG plaster is applied to affected part, and changed for 12 hr for 1 time, and 10 days is 1 treatment course, and three treatment courses are total. Blank group: three courses of treatment were performed without any treatment.
2. Observation index
Patients in the blank group, the test group and the control group are scored for cervical spondylosis and lumbar disc herniation pain after three treatment courses of treatment by adopting a VAS (visual analogue scoring) method. The pain degree is quantified to be 0-10 points, and the higher the score is, the stronger the pain degree is. The severity of the disease was assessed using the JOA (japan orthopedics association assessment treatment score) score: the score was 29 points full, the lower the score, the more obvious the dysfunction.
3. Statistical analysis
SPSS21.0 statistical software is adopted for data processing, the measurement data is expressed by mean plus or minus standard deviation (x plus or minus s), t test is carried out, and P <0.05 is difference, which has statistical significance.
4. Therapeutic results
After three courses of treatment, the follow-up statistics were as follows:
TABLE 2 VAS and JOA Scoring comparison for different groups of cervical spondylosis and prolapse of lumbar intervertebral disc (x + -s, points)
Note: p <0.05 compared to blank group
The VAS and CMS score comparison results of different groups of cervical spondylosis and lumbar disc herniation are shown in the figure 2, test III: clinical efficacy test for osteoarthritis
1. Test method
50 patients with osteoarthritis were selected. 25 of the male patients and 25 of the female patients; age 45-57 years, mean 50.9 years; the disease course is 6-8 months, and the average (7 +/-0.8) month; the two groups have no significant difference (P >0.05) in disease conditions, age, course and the like, and have comparability.
Test groups: the far infrared physiotherapy patch prepared in the embodiment 3 is applied to an affected part, and is replaced for 1 time in 12 hours, 10 days are 1 treatment course, and three treatment courses are total. Control group: the QIZHENGXIAOTONG plaster is applied to affected part, and is changed for 12h for 1 time, 10 days is 1 treatment course, and three treatment courses are total. Blank group: no treatment is carried out, and three treatment courses are carried out.
2. Observation index
Patients in the blank group, the test group and the control group are scored for cervical spondylosis and lumbar disc herniation pain after three treatment courses of treatment by adopting a VAS (visual analogue scoring) method. The pain degree is quantified to be 0-10 points, and the higher the score is, the stronger the pain degree is. Joint function in patients is assessed using a Lequesne score (the index of the evolution of the function of the quison), with lower scores indicating less symptoms.
3. Statistical analysis
SPSS21.0 statistical software is adopted for data processing, the measurement data is expressed by mean plus or minus standard deviation (x plus or minus s), t test is carried out, and P <0.05 is difference, which has statistical significance.
4. Therapeutic results
Three groups of patients were treated for three courses of treatment, and the statistical results of the visits were as follows:
TABLE 3 comparison of the VAS and Lequesne scores for osteoarthritis (x. + -. s, points)
P <0.05 x compared to blank group
The VAS and Lequesne scores of osteoarthritis are compared, and the result is shown in FIG. 3
And (4) testing: clinical efficacy in soft tissue injury (non-acute phase)
1. Experimental methods
50 patients with soft tissue injury (non-acute phase) were selected. 25 of the male patients and 25 of the female patients; age 45-57 years, mean 50.9 years; the course of the disease is 6-8 months, and the average (7 +/-0.8) month; the two groups have no significant difference (P >0.05) in disease conditions, age, course and the like, and have comparability.
Test groups: the far infrared physiotherapy patch prepared in the embodiment 3 is applied to an affected part, and is replaced for 1 time in 12 hours, 10 days are 1 treatment course, and three treatment courses are total. Control group: the Qizheng Xiaotong plaster is applied to the affected shoulder, and is replaced for 1 time in 12 hours, 10 days are 1 treatment course, and three treatment courses are total.
2. Evaluation index
Clinical effects of two groups of patients were compared, and the recovery criteria were: the clinical condition of the patient completely disappears and the function of the patient is recovered. The effective standard is as follows: the patient had significantly reduced cardinal symptoms; invalidation criteria: the patient's primary symptoms did not improve, or even worsen.
3. Statistical analysis
SPSS21.0 statistical software is adopted for data processing, the measurement data is expressed by mean plus or minus standard deviation (x plus or minus s), t test is carried out, and P <0.05 is difference, which has statistical significance.
4. Therapeutic results
Three groups of patients were treated for three courses of treatment, and the statistical results of the visits were as follows:
TABLE 4 comparison of the clinical treatment effects of Soft tissue injury (non-acute phase)
P <0.05 x compared to control group
A graph of the results of comparing the clinical treatment effects of soft tissue injury (non-acute phase) is shown in FIG. 4
And (5) testing: analgesia experiment of far infrared physiotherapy plaster
1. Experimental methods
30 mice, the abdomens of which were shaved, were randomly divided into a blank group, a control group and a test group, each group consisting of 10 mice, each half of which was male and female. The far infrared physiotherapy plaster is respectively pasted on the abdomen of the mouse in the model group, and the control group comprises: the Qizheng Xiaotong plaster is applied to the abdomen of the mouse, and the plaster prepared by the blank group without medicine matrix is applied for 6 hours. Mice were injected with 0.1ml/10g of 1% acetic acid (v/v).
2. Statistical analysis
The frequency of 20-minute writhing of the mice injected with acetic acid is recorded, SPSS21.0 statistical software is adopted for data processing, the measurement data is expressed by mean number plus or minus standard deviation (x plus or minus s), t test is carried out, and the difference is statistically significant when P is less than 0.05.
3. Therapeutic results
TABLE 5 comparison of results of 20 minute writhing in mice
P <0.05 x compared to control group
Results of the frequency of 20 min writhing in mice are compared with the results in figure 5
Compared with the physiotherapy patch products on the market, the far infrared physiotherapy patch prepared by the invention has more remarkable effects of assisting in treating cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, osteoarthritis and soft tissue injury (in a non-acute stage) and relieving pain.
Claims (6)
1. A preparation method and application of a far infrared physiotherapy patch are characterized by comprising the following steps:
(1) adding the traditional Chinese medicine powder and the ceramic powder into the acrylic pressure-sensitive adhesive, and stirring to form a viscous mixture with certain fluidity, so that the viscous mixture can be coated and can not flow in a backing material;
(2) uniformly coating the sticky mixture obtained in the step (1) on non-woven fabric to obtain a sheet;
(3) and (3) drying the sheet obtained in the step (2) by using an oven to obtain a continuous, flat and smooth sheet, protecting the sticky surface by using silicone oil paper to form a sticky sheet, and cutting the sticky sheet into a fixed shape to obtain the far infrared physical therapy patch.
2. The preparation method and the application of the far infrared physiotherapy plaster according to claim 1, wherein the preferable mass percentages of the traditional Chinese medicine powder, the ceramic powder and the acrylic acid pressure-sensitive adhesive in the step (1) are as follows: 25-50% of traditional Chinese medicine powder, 10-30% of ceramic powder and 20-45% of acrylic pressure-sensitive adhesive.
3. The preparation method and the application of the far infrared physiotherapy plaster according to claim 1, wherein the traditional Chinese medicine powder in the step (1) comprises the following components in percentage by mass: 15-30% of obscured homalomena rhizome, 10-30% of diverse wormwood herb, 10-20% of turmeric, 10-20% of Chinese starjasmine stem, 10-15% of garden balsam stem and 10-15% of catechu.
4. The preparation method and the application of the far infrared physiotherapy plaster as claimed in claim 1, wherein the ceramic powder in the step (1) is far infrared ceramic powder with fineness of more than 2000 meshes.
5. The preparation method and application of the far infrared physiotherapy plaster as claimed in claim 1, wherein the traditional Chinese medicine powder in step (1) is sieved with 100 mesh sieve.
6. The preparation method of claim 1, wherein the far infrared physiotherapy patch is used for adjuvant treatment of cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, osteoarthritis and soft tissue injury (non-acute stage).
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106729400A (en) * | 2016-12-23 | 2017-05-31 | 李云科 | A kind of exterior-applied medical wine for the treatment of of arthritis |
| CN108567766A (en) * | 2018-06-05 | 2018-09-25 | 史锐 | A kind of ventilation patch and preparation method thereof |
| CN113577043A (en) * | 2021-07-21 | 2021-11-02 | 江苏达胜伦比亚生物科技有限公司 | Preparation process of far infrared physiotherapy plaster |
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- 2022-03-25 CN CN202210284774.6A patent/CN114558098A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106729400A (en) * | 2016-12-23 | 2017-05-31 | 李云科 | A kind of exterior-applied medical wine for the treatment of of arthritis |
| CN108567766A (en) * | 2018-06-05 | 2018-09-25 | 史锐 | A kind of ventilation patch and preparation method thereof |
| CN113577043A (en) * | 2021-07-21 | 2021-11-02 | 江苏达胜伦比亚生物科技有限公司 | Preparation process of far infrared physiotherapy plaster |
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