CN114555571B - 作为NLRP3调节剂的N-((1,2,3,5,6,7-六氢-s-引达省-4-基)氨甲酰基)-4,5,6,7-四氢苯并呋喃-2-磺酰胺衍生物 - Google Patents

作为NLRP3调节剂的N-((1,2,3,5,6,7-六氢-s-引达省-4-基)氨甲酰基)-4,5,6,7-四氢苯并呋喃-2-磺酰胺衍生物 Download PDF

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CN114555571B
CN114555571B CN202080064480.1A CN202080064480A CN114555571B CN 114555571 B CN114555571 B CN 114555571B CN 202080064480 A CN202080064480 A CN 202080064480A CN 114555571 B CN114555571 B CN 114555571B
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pharmaceutically acceptable
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CN114555571A (zh
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拉朱·莫汉
约翰·努斯
詹森·哈里斯
袁沈东
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Zumazhen Bioscience Co ltd
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CN202080064480.1A 2019-07-17 2020-07-16 作为NLRP3调节剂的N-((1,2,3,5,6,7-六氢-s-引达省-4-基)氨甲酰基)-4,5,6,7-四氢苯并呋喃-2-磺酰胺衍生物 Active CN114555571B (zh)

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US201962875402P 2019-07-17 2019-07-17
US62/875,402 2019-07-17
PCT/IB2020/000634 WO2021009566A1 (en) 2019-07-17 2020-07-16 N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,5,6,7-tetrahydrobenzofuran -2-sulfonamide derivatives and related compounds as nlpr3 modulators for the treatment of multiple sclerosis (ms)

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CN114555571B true CN114555571B (zh) 2024-08-27

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IL289885A (en) 2022-03-01
EP3999496B1 (en) 2024-12-18
CN114555571A (zh) 2022-05-27
WO2021009566A1 (en) 2021-01-21
US12466800B2 (en) 2025-11-11
AU2020312800A1 (en) 2022-02-24
BR112022000878A2 (pt) 2022-04-19
KR20220064364A (ko) 2022-05-18
CA3151865A1 (en) 2021-01-21
EP3999496A1 (en) 2022-05-25
MX2022000646A (es) 2022-05-20

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