CN114533833A - Traditional Chinese medicine composition for warming viscera and application thereof - Google Patents
Traditional Chinese medicine composition for warming viscera and application thereof Download PDFInfo
- Publication number
- CN114533833A CN114533833A CN202210175688.1A CN202210175688A CN114533833A CN 114533833 A CN114533833 A CN 114533833A CN 202210175688 A CN202210175688 A CN 202210175688A CN 114533833 A CN114533833 A CN 114533833A
- Authority
- CN
- China
- Prior art keywords
- parts
- rhizoma
- traditional chinese
- chinese medicine
- viscera
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 47
- 239000000203 mixture Substances 0.000 title claims abstract description 42
- 210000001835 viscera Anatomy 0.000 title claims abstract description 38
- 238000010792 warming Methods 0.000 title claims abstract description 34
- 244000203593 Piper nigrum Species 0.000 claims abstract description 27
- 235000008184 Piper nigrum Nutrition 0.000 claims abstract description 27
- 208000004998 Abdominal Pain Diseases 0.000 claims abstract description 20
- 206010011469 Crying Diseases 0.000 claims abstract description 15
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 14
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 14
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 14
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 14
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 14
- 235000013614 black pepper Nutrition 0.000 claims abstract description 14
- 229940116229 borneol Drugs 0.000 claims abstract description 14
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000005300 cardamomo Nutrition 0.000 claims abstract description 14
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000001931 piper nigrum l. white Substances 0.000 claims abstract description 14
- 235000002566 Capsicum Nutrition 0.000 claims abstract description 13
- 241000007126 Codonopsis pilosula Species 0.000 claims abstract description 13
- 239000006002 Pepper Substances 0.000 claims abstract description 13
- 235000016761 Piper aduncum Nutrition 0.000 claims abstract description 13
- 235000017804 Piper guineense Nutrition 0.000 claims abstract description 13
- 206010019847 hepatosplenomegaly Diseases 0.000 claims abstract description 13
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 11
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 11
- 206010000060 Abdominal distension Diseases 0.000 claims abstract description 10
- 206010047700 Vomiting Diseases 0.000 claims abstract description 10
- 230000008673 vomiting Effects 0.000 claims abstract description 10
- 241000132012 Atractylodes Species 0.000 claims abstract description 8
- 206010012735 Diarrhoea Diseases 0.000 claims abstract description 8
- 240000004760 Pimpinella anisum Species 0.000 claims abstract description 6
- 235000012550 Pimpinella anisum Nutrition 0.000 claims abstract description 6
- 230000004064 dysfunction Effects 0.000 claims abstract description 5
- 240000002943 Elettaria cardamomum Species 0.000 claims abstract 4
- 241001127714 Amomum Species 0.000 claims description 14
- 238000002360 preparation method Methods 0.000 claims description 13
- 241001346334 Amomum tsao-ko Species 0.000 claims description 5
- 235000013399 edible fruits Nutrition 0.000 claims description 4
- 230000000422 nocturnal effect Effects 0.000 claims description 4
- 241000213006 Angelica dahurica Species 0.000 claims description 3
- 241000934856 Daphne Species 0.000 claims description 3
- 241001163443 Daphne giraldii Species 0.000 claims description 3
- 230000009278 visceral effect Effects 0.000 claims description 3
- 241000037740 Coptis chinensis Species 0.000 claims description 2
- 230000000699 topical effect Effects 0.000 claims 2
- 208000037911 visceral disease Diseases 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 11
- 208000024891 symptom Diseases 0.000 abstract description 9
- 201000010099 disease Diseases 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 11
- 239000000843 powder Substances 0.000 description 11
- 238000011084 recovery Methods 0.000 description 8
- 210000000952 spleen Anatomy 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 206010038743 Restlessness Diseases 0.000 description 5
- 208000001431 Psychomotor Agitation Diseases 0.000 description 4
- 206010037660 Pyrexia Diseases 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 241000316770 Deschampsia cespitosa var. alpina Species 0.000 description 3
- 235000007265 Myrrhis odorata Nutrition 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 210000002540 macrophage Anatomy 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 230000001314 paroxysmal effect Effects 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 241000046691 Daphne odora Species 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 206010039740 Screaming Diseases 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- 206010007027 Calculus urinary Diseases 0.000 description 1
- 241001649187 Campsis radicans Species 0.000 description 1
- 240000004160 Capsicum annuum Species 0.000 description 1
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 206010015137 Eructation Diseases 0.000 description 1
- 235000004204 Foeniculum vulgare Nutrition 0.000 description 1
- 240000006927 Foeniculum vulgare Species 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 206010027924 Mononucleosis syndrome Diseases 0.000 description 1
- 208000032140 Sleepiness Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 208000009911 Urinary Calculi Diseases 0.000 description 1
- 208000012876 acute enteritis Diseases 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 201000009361 ascariasis Diseases 0.000 description 1
- 210000003719 b-lymphocyte Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000013 bile duct Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 239000012636 effector Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000005713 exacerbation Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000007124 immune defense Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 208000003243 intestinal obstruction Diseases 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 206010034674 peritonitis Diseases 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 210000004180 plasmocyte Anatomy 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 210000003689 pubic bone Anatomy 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000037321 sleepiness Effects 0.000 description 1
- 210000001562 sternum Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 210000001113 umbilicus Anatomy 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/235—Foeniculum (fennel)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine composition for warming viscera, which comprises the following components in parts by mass: 8-25 parts of rhizoma atractylodis, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of radix coptidis, 1-10 parts of rhizoma coptidis, 5-17 parts of aniseed, 1-10 parts of xiaoxiang, 1-10 parts of cassia bark, 1-8 parts of pepper, 5-16 parts of rhizoma kaempferiae, 5-15 parts of radix angelicae, 1-8 parts of fructus amomi, 1-8 parts of cardamom, 5-15 parts of amom tsaoko, 8-22 parts of folium artemisiae argyi, 0.5-5 parts of white pepper, 1-8 parts of codonopsis pilosula, 0.5-5 parts of Chinese yam and 0.1-1 part of borneol. The traditional Chinese medicine composition for warming and nourishing viscera provided by the invention can effectively improve symptoms of night cry, crying, angry, abdominal distension, vomiting, diarrhea and the like of a newborn caused by viscera dysfunction in a certain proportion range, and has an obvious treatment effect on abdominal pain and hepatosplenomegaly of school-age children.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compounding, and relates to a traditional Chinese medicine composition for warming viscera and application thereof.
Background
The nocturnal fretfulness of infants is a phenomenon that infants normally behave in the daytime and cry seriously and ceaselessly at night. After suffering from this disease, the duration is few days, and more days, it is a menstruation. The expression is as follows: infants cry constantly at night and are normal in the day. Or cry in a burst, or the trumpet creeper can still sleep after crying; or red face and lips, paroxysmal abdominal pain, abdominal distension and vomiting, or panic and hoarseness. Traditional Chinese medicine considers that nocturnal fretfulness in infants is often caused by spleen cold, heart heat, fright and indigestion. (1) Deficiency-cold of spleen and stomach, manifested by pale complexion, lack of warmth in limbs, preference for lying on the back, cold abdomen, stooping, crying, poor appetite, thin stool, and clear and long urine in children. The tongue is pale with white coating, the pulse is thready and slow, and the fingerprint is pale red. For treatment, it should warm the middle energizer and invigorate the spleen. (2) The symptoms of the heart-heat are fright, red lips and red lips, dysphoria, mouth and nose with fever, night sleep restlessness, a fright with a first glance, warm body and abdomen, constipation and scanty and brownish urine. A red tongue tip with yellow coating and a slippery and rapid pulse. For heat-clearing and tranquilization. (3) Fear in fright, manifested as night crying, reddened or bluish face, restlessness, easy waking up during sleep, crying in dream, and a terrific and dreaded sound, which is felt tightly by the mother and the pulse like lip and tongue is almost unchanged. For it is good at relieving convulsion and tranquilizing mind. (4) Food retention in the breast is manifested as night crying, anorexia, vomiting of milk, eructation with rotten acid and acid, abdominal pain and fullness, sleepiness, restlessness, acid and foul stools, thick and greasy tongue coating, and purple-stagnation of finger-prints.
Abdominal pain is one of the common symptoms in pediatrics, and pain occurring in the areas under the sternum, on both sides of the umbilicus and above the pubic bone are collectively called abdominal pain. The causes of the abdominal pain of children with different ages are different. Paroxysmal abdominal pain, often seen as intestinal obstruction or urinary calculus. Those with extremely irregular outbreaks are usually the internal diseases, such as intestinal ascariasis and acute enteritis. Persistent abdominal pain, aggravated when the body position is changed, and abdominal pain with tenderness, is often the manifestation of localized or diffuse peritonitis. Fever occurs immediately after onset, indicating an inflammatory disease. If the disease does not have fever at the beginning, the patient will have fever later, and the secondary infection is usually seen. When the infant suffers from abdominal pain, the infant often has crying, restlessness and expression pain, and when the paroxysmal exacerbation occurs, the infant cryes with loud voice, is restless in sitting or lying, or is reduced or relieved in abdominal pain after rolling on a bed, pressing the abdomen tightly or hot compressing, and may be spasm of tubular organs such as intestinal canal, bile duct and the like.
Viral diseases are common diseases in humans. Statistically, 3/4 is caused by viruses, and children are often susceptible to viral diseases. Because the immune defense system and the functions of various organs of children are not completely developed and mature, the children are more easily invaded by viruses than adults, and hepatosplenomegaly is more easily caused in the virus infection process. The spleen is the largest peripheral immune organ and has direct relation with immune function, T cells and B cells enrich the spleen, when an organism is stimulated by antigen, lymph tissues are proliferated, lymphocytes, plasma cells and macrophages are proliferated and carry out immune response, and the spleen is enlarged due to the production of antibodies and a large amount of T effector cells. The liver is rich in macrophages, and the antigens stimulate the proliferation of the macrophages to cause the enlargement of the liver. In addition, some metabolites are deposited or abnormally infiltrated with cells, and clinically, signs of hepatosplenomegaly may also be present.
The newborn cry at night, anger, abdominal distension, vomiting and diarrhea, abdominal pain of school-age children and hepatosplenomegaly belong to common symptoms in pediatrics, and no good western medicine preparation for treating related diseases is available at present. The traditional Chinese medicine can regulate the functions of viscera on the whole, is a method for eliminating related diseases to a great extent by improving the immunity of human bodies, has stable effects of reducing enzyme, removing jaundice, resisting virus and improving symptoms and small side effect, and is a treatment method worthy of research.
Disclosure of Invention
The invention aims to provide a composition for effectively treating visceral dysfunction diseases.
In view of the above, the present application addresses this need in the art by providing a Chinese medicinal composition for warming viscera and its use, which is effective for warming viscera and treating visceral dysfunction, and has excellent effects in treating nocturnal fretting and crying of newborns, flatulence, abdominal distension, vomiting, diarrhea, abdominal pain in school-age children, hepatosplenomegaly, and the like.
On one hand, the invention relates to a traditional Chinese medicine composition for warming viscera, which comprises the following components in parts by mass: 8-25 parts of rhizoma atractylodis, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of radix coptidis, 1-10 parts of rhizoma coptidis, 5-17 parts of aniseed, 1-10 parts of xiaoxiang, 1-10 parts of cassia bark, 1-8 parts of pepper, 5-16 parts of rhizoma kaempferiae, 5-15 parts of radix angelicae, 1-8 parts of fructus amomi, 1-8 parts of cardamom, 5-15 parts of amom tsaoko, 8-22 parts of folium artemisiae argyi, 0.5-5 parts of white pepper, 1-8 parts of codonopsis pilosula, 0.5-5 parts of Chinese yam and 0.1-1 part of borneol.
Preferably, the traditional Chinese medicine composition for warming and nourishing viscera provided by the invention comprises the following components in parts by mass: 10-18 parts of rhizoma atractylodis, 7-12 parts of bighead atractylodes rhizome, 7-12 parts of rhizoma coptidis, 3-6 parts of rhizoma polygonati, 7-12 parts of daphne giraldii, 3-6 parts of xiaoxiang, 3-6 parts of cassia bark, 3-6 parts of pepper, 7-12 parts of rhizoma kaempferiae, 7-12 parts of radix angelicae, 3-6 parts of fructus amomi, 3-6 parts of cardamom, 7-12 parts of amomum tsao-ko, 10-18 parts of folium artemisiae argyi, 1-3 parts of white pepper, 3-6 parts of codonopsis pilosula, 1-3 parts of Chinese yam and 0.3-0.5 part of borneol.
Preferably, the traditional Chinese medicine composition for warming and nourishing viscera provided by the invention comprises the following components in parts by mass: 12 parts of rhizoma atractylodis, 8 parts of bighead atractylodes rhizome, 8 parts of radix coptidis, 4.5 parts of coptis chinensis, 8 parts of daphne aromatica, 4.5 parts of xiaoxiang, 3.7 parts of cassia bark, 3.7 parts of pepper, 8 parts of rhizoma kaempferiae, 3.7 parts of angelica dahurica, 3.7 parts of fructus amomi, 3.5 parts of cardamom, 7 parts of tsaoko amomum fruit, 8 parts of folium artemisiae argyi, 1.5 parts of white pepper, 3.5 parts of codonopsis pilosula, 2 parts of Chinese yam and 0.4 part of borneol.
Further, the invention also provides a preparation method of the traditional Chinese medicine composition for warming and nourishing viscera, which comprises the following steps:
taking rhizoma atractylodis, bighead atractylodes rhizome, rhizoma coptidis, daphne odora, fennel, cassia bark, pepper, rhizoma kaempferiae, angelica dahurica, fructus amomi, cardamom, amomum tsao-ko, folium artemisiae argyi, white pepper, codonopsis pilosula, Chinese yam and borneol in parts by weight, respectively pounding the raw materials into fine powder or paste, and mixing the fine powder or paste to obtain the traditional Chinese medicine preparation of the traditional Chinese medicine composition for warming and nourishing viscera.
Compared with the prior art, the invention has the following beneficial effects or advantages:
compared with the prior art, the main contribution of the invention is to provide a traditional Chinese medicine composition for warming and nourishing viscera, which comprises rhizoma atractylodis, rhizoma atractylodis macrocephalae, radix coptidis, daphne fragrans, fructus cinnamomi, cortex cinnamomi japonici, pericarpium zanthoxyli, rhizoma kaempferiae, radix angelicae, fructus amomi, cardamom, fructus amomi, cardamomi, amomum tsao-ko, folium artemisiae argyi, white pepper, codonopsis pilosula, Chinese yam and borneol. The inventor of the patent conducts pharmacodynamic tests on the traditional Chinese medicine composition, and finds that the composition shows excellent effects on warming and nourishing viscera and treating viscera dysfunction diseases by external application within a certain proportion range, and is particularly suitable for external application for treating pediatric diseases in the aspects of night cry and crying of newborns, anger and abdominal distension, vomiting and diarrhea, abdominal pain of school-age children, hepatosplenomegaly and the like.
Detailed Description
The following examples are given to illustrate the technical aspects of the present invention, but the present invention is not limited to the following examples.
Example 1
This example provides a process for preparing a Chinese medicinal composition for warming and nourishing the viscera.
The traditional Chinese medicine preparation of the traditional Chinese medicine composition for warming and nourishing the internal organs is prepared by smashing 8 parts of rhizoma atractylodis, 5 parts of rhizoma atractylodis macrocephalae, 5 parts of rhizoma coptidis, 5 parts of daphne giraldii, 1 part of cortex cinnamomi japonici, 1 part of pepper, 5 parts of rhizoma kaempferiae, 5 parts of radix angelicae, 1 part of fructus amomi, 1 part of cardamom, 1 part of hassock, 5 parts of fructus tsaoko, 8 parts of folium artemisiae argyi, 0.5 part of white pepper, 1 part of codonopsis pilosula, 0.5 part of Chinese yam and 0.1 part of borneol into fine powder or paste respectively by mass parts and mixing the fine powder or the paste.
Example 2
This example provides a process for preparing a Chinese medicinal composition for warming and nourishing the viscera.
Taking 10 parts of rhizoma atractylodis, 7 parts of rhizoma atractylodis macrocephalae, 7 parts of rhizoma coptidis, 3 parts of rhizoma atractylodis macrocephalae, 7 parts of radix angelicae, 7 parts of daphne odora, 3 parts of fructus cinnamomi, 3 parts of pepper, 7 parts of rhizoma kaempferiae, 7 parts of radix angelicae, 3 parts of fructus amomi, 3 parts of cardamom, 3 parts of hassock, 7 parts of fructus tsaoko, 10 parts of folium artemisiae argyi, 1 part of white pepper, 3 parts of radix codonopsis pilosulae, 1 part of Chinese yam and 0.3 part of borneol, respectively pounding the raw materials into fine powder or paste, and mixing the fine powder or the paste to obtain the traditional Chinese medicine preparation of the traditional Chinese medicine composition for warming and nourishing viscera.
Example 3
This example provides a process for preparing a Chinese medicinal composition for warming and nourishing the viscera.
Taking 12 parts of rhizoma atractylodis, 8 parts of rhizoma atractylodis macrocephalae, 8 parts of rhizoma coptidis, 4.5 parts of rhizoma coptidis, 8 parts of anise, 4.5 parts of xiaoxiang, 3.7 parts of cassia bark, 3.7 parts of pepper, 8 parts of rhizoma kaempferiae, 3.7 parts of radix angelicae, 3.7 parts of fructus amomi, 3.5 parts of cardamom, 3.5 parts of amomum tsao-ko, 7 parts of fructus tsaoko, 8 parts of folium artemisiae argyi, 1.5 parts of white pepper, 3.5 parts of codonopsis pilosula, 2 parts of Chinese yam and 0.4 part of borneol by mass, respectively pounding into fine powder or paste, and mixing to obtain the traditional Chinese medicine preparation of the traditional Chinese medicine composition for warming viscera.
Example 4
This example provides a process for preparing a Chinese medicinal composition for warming and nourishing the viscera.
The traditional Chinese medicine preparation of the traditional Chinese medicine composition for warming and nourishing the internal organs is prepared by respectively pounding 18 parts of rhizoma atractylodis, 12 parts of rhizoma atractylodis macrocephalae, 12 parts of rhizoma coptidis, 12 parts of anise, 6 parts of pimento, 6 parts of cassia bark, 6 parts of pepper, 12 parts of rhizoma kaempferiae, 12 parts of radix angelicae, 6 parts of fructus amomi, 6 parts of cardamom, 12 parts of amom tsaoko amomum fruit, 18 parts of folium artemisiae argyi, 3 parts of white pepper, 6 parts of codonopsis pilosula, 3 parts of Chinese yam and 0.5 part of borneol into fine powder or paste and mixing the fine powder or the paste.
Example 5
This example provides a process for preparing a Chinese medicinal composition for warming and nourishing the viscera.
The traditional Chinese medicine preparation of the traditional Chinese medicine composition for warming and nourishing the internal organs is prepared by smashing 25 parts of rhizoma atractylodis, 15 parts of rhizoma atractylodis macrocephalae, 15 parts of rhizoma coptidis, 10 parts of rhizoma atractylodis, 17 parts of anise, 10 parts of xiaoxiang, 10 parts of cassia bark, 8 parts of pepper, 16 parts of rhizoma kaempferiae, 15 parts of radix angelicae, 8 parts of fructus amomi, 8 parts of cardamom, 8 parts of hassock, 15 parts of tsaoko amomum fruit, 22 parts of folium artemisiae argyi, 5 parts of white pepper, 8 parts of codonopsis pilosula, 5 parts of Chinese yam and 1 part of borneol into fine powder or paste respectively and mixing the fine powder or the paste.
Example 6
The embodiment provides an application effect test of a traditional Chinese medicine composition for warming and nourishing viscera in treating night crying and crying of newborns, angry and abdominal distension, vomiting and diarrhea.
250 infants are screened in various hospitals, and all the selected patients have the symptoms of night cry, crying and screaming, angry qi and abdominal distension, vomiting and diarrhea, wherein 125 girls and 125 boys have the age distribution of the patients in 1-10 months. Patients were randomized into groups of 200 in the experimental group and 50 in the control group. The experimental components were 5 groups, and 40 patients in each group were each administered with the Chinese medicinal preparations obtained in examples 1 to 5, as shown in Table 1. The external application method comprises applying the Chinese medicinal preparation on the surface of a patient, fixing the medicine with bellyband to completely cover the navel of the patient, wherein the covering area is greater than 1/2, the application time is greater than 8 hours every night for 1 time, the medicine is removed the next morning, and the medicine is continuously applied for 5 days. The control group is conventional medicine control group, wherein the conventional medicine is infantile night cry granule, and the administration method is described in the specification. The criteria for determining the therapeutic effect are as follows: ineffectiveness-after treatment, malaise symptoms did not change or recur; effective-after treatment, discomfort symptoms are alleviated; recovery-after treatment, the malaise symptoms disappear and no recurrence occurs. The statistical treatment was performed on days 1, 3 and 5 of treatment, and the specific results are shown in table 1.
TABLE 1 therapeutic effect of a Chinese medicinal composition for warming viscera for treating newborn
As can be seen from Table 1, the maximum recovery rate in the test group of a Chinese medicinal composition for warm-nourishing viscera was 77.5%, while the recovery rate in the case of taking conventional drugs was 44.0%. In addition, the traditional Chinese medicine composition for warming and nourishing viscera provided in the external application example 3 has better performance effect, especially on the aspect of recovery rate, compared with other examples. Therefore, the traditional Chinese medicine composition for warming and nourishing viscera provided by the invention has excellent effects on treating night crying and screaming of newborn, anger and abdominal distension, vomiting and diarrhea.
Example 7
The embodiment provides an application effect test of a traditional Chinese medicine composition for warming and nourishing viscera in treating abdominal pain and hepatosplenomegaly of school-age children.
100 school-age children (6-12 years old) are screened in various hospitals, and the patients complain of abdominal pain and diagnosed as mononucleosis syndrome, serum liver enzyme is slightly increased, hepatosplenomegaly is 20-25%, and jaundice is about 3%. Patients were randomized into groups of 150 in the experimental group and 50 in the control group. Both patients received general treatment measures, wherein the experimental components are 5 groups, 30 patients in each group are respectively externally applied with the traditional Chinese medicine preparation (the raw material dosage is 10g) obtained in the examples 1-5 every day, and the placebo with equal dosage is externally applied to the control group. The external application method comprises applying 10g of the Chinese medicinal preparation on navel, wrapping with gauze, fixing with medical adhesive tape, applying for 22:00 each night to 8:00 the next morning, and revisiting to examine the hepatosplenomegaly of patients after continuous external application for 15 days, and counting. The criteria for determining the therapeutic effect are as follows: ineffectiveness-after treatment, there was no change in hepatosplenomegaly or recurrent abdominal pain; effective-following treatment, hepatosplenomegaly is reduced; after recovery, the liver and spleen are recovered to be normal without relapse and abdominal pain. Specific results are shown in table 2.
TABLE 2 therapeutic effect of a Chinese medicinal composition for warming viscera in school-age children
| Test group | Null (%) | Effective (%) | Healing recovery (%) |
| Example 1 | 16.7 | 13.3 | 70.0 |
| Example 2 | 10.0 | 10.0 | 80.0 |
| Example 3 | 3.3 | 10.0 | 86.7 |
| Example 4 | 6.7 | 10.0 | 83.3 |
| Example 5 | 13.3 | 3.3 | 83.3 |
| Control group | 18.0 | 20.0 | 62.0 |
As can be seen from Table 2, the maximum recovery rate of the test group of the externally applied traditional Chinese medicine composition for warming viscera was 86.7%, while the recovery rate of the control group was 62.0%, and the test group and the control group had significant differences. In addition, the traditional Chinese medicine composition for warming and nourishing viscera provided in example 3 has better performance effect, especially in the aspect of recovery rate, compared with other examples. Therefore, the traditional Chinese medicine composition for warming and nourishing viscera provided by the invention has excellent effects in treating abdominal pain and hepatosplenomegaly of school-age children.
As described above, the present invention can be preferably implemented, and the above-mentioned embodiments only describe the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various changes and modifications of the technical solution of the present invention made by those skilled in the art without departing from the design spirit of the present invention shall fall within the protection scope defined by the present invention.
Claims (7)
1. The traditional Chinese medicine composition for warming and nourishing viscera is characterized by comprising the following components in parts by mass: 8-25 parts of rhizoma atractylodis, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of radix coptidis, 1-10 parts of rhizoma coptidis, 5-17 parts of aniseed, 1-10 parts of xiaoxiang, 1-10 parts of cassia bark, 1-8 parts of pepper, 5-16 parts of rhizoma kaempferiae, 5-15 parts of radix angelicae, 1-8 parts of fructus amomi, 1-8 parts of cardamom, 5-15 parts of amom tsaoko, 8-22 parts of folium artemisiae argyi, 0.5-5 parts of white pepper, 1-8 parts of codonopsis pilosula, 0.5-5 parts of Chinese yam and 0.1-1 part of borneol.
2. The traditional Chinese medicine composition according to claim 1, wherein the composition comprises, in parts by mass: 10-18 parts of rhizoma atractylodis, 7-12 parts of bighead atractylodes rhizome, 7-12 parts of rhizoma coptidis, 3-6 parts of rhizoma polygonati, 7-12 parts of daphne giraldii, 3-6 parts of xiaoxiang, 3-6 parts of cassia bark, 3-6 parts of pepper, 7-12 parts of rhizoma kaempferiae, 7-12 parts of radix angelicae, 3-6 parts of fructus amomi, 3-6 parts of cardamom, 7-12 parts of amomum tsao-ko, 10-18 parts of folium artemisiae argyi, 1-3 parts of white pepper, 3-6 parts of codonopsis pilosula, 1-3 parts of Chinese yam and 0.3-0.5 part of borneol.
3. The traditional Chinese medicine composition according to claim 1, wherein the composition comprises, in parts by mass: 12 parts of rhizoma atractylodis, 8 parts of bighead atractylodes rhizome, 8 parts of radix coptidis, 4.5 parts of coptis chinensis, 8 parts of daphne aromatica, 4.5 parts of xiaoxiang, 3.7 parts of cassia bark, 3.7 parts of pepper, 8 parts of rhizoma kaempferiae, 3.7 parts of angelica dahurica, 3.7 parts of fructus amomi, 3.5 parts of cardamom, 7 parts of tsaoko amomum fruit, 8 parts of folium artemisiae argyi, 1.5 parts of white pepper, 3.5 parts of codonopsis pilosula, 2 parts of Chinese yam and 0.4 part of borneol.
4. A Chinese medicinal external preparation, comprising the Chinese medicinal composition of claim 1.
5. An external medicine for treating visceral dysfunction, which comprises the Chinese medicinal composition of claim 1.
6. The topical medicament of claim 5, wherein the visceral disorders comprise nocturnal crying and crying, anger and abdominal distension, vomiting and diarrhea in newborn infants.
7. The topical medicament of claim 5, wherein the visceral disorders comprise abdominal pain and hepatosplenomegaly in school-age children.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210175688.1A CN114533833A (en) | 2022-02-25 | 2022-02-25 | Traditional Chinese medicine composition for warming viscera and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210175688.1A CN114533833A (en) | 2022-02-25 | 2022-02-25 | Traditional Chinese medicine composition for warming viscera and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114533833A true CN114533833A (en) | 2022-05-27 |
Family
ID=81679474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210175688.1A Pending CN114533833A (en) | 2022-02-25 | 2022-02-25 | Traditional Chinese medicine composition for warming viscera and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114533833A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1119949A (en) * | 1994-12-26 | 1996-04-10 | 王天成 | Fragrant medicine bag |
| CN1125528A (en) * | 1994-12-30 | 1996-07-03 | 段克儒 | Flavouring liquid and its manufacture method |
| CN111419933A (en) * | 2020-05-28 | 2020-07-17 | 程亚伟 | Traditional Chinese medicine composition for tonifying spleen and promoting appetite and external preparation and application thereof |
-
2022
- 2022-02-25 CN CN202210175688.1A patent/CN114533833A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1119949A (en) * | 1994-12-26 | 1996-04-10 | 王天成 | Fragrant medicine bag |
| CN1125528A (en) * | 1994-12-30 | 1996-07-03 | 段克儒 | Flavouring liquid and its manufacture method |
| CN111419933A (en) * | 2020-05-28 | 2020-07-17 | 程亚伟 | Traditional Chinese medicine composition for tonifying spleen and promoting appetite and external preparation and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 邢建生: "小儿兜肚治疗小儿泄泻112例", 《陕西中医》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103520572B (en) | A kind of Chinese medicine composition being used for the treatment of atopic dermatitis and preparation method thereof | |
| CN104740583A (en) | Traditional Chinese medicine preparation for relieving Crohn's disease and preparation method for traditional Chinese medicine preparation | |
| CN114533833A (en) | Traditional Chinese medicine composition for warming viscera and application thereof | |
| CN103301353B (en) | Pharmaceutical composition for treating atrophic vaginitis | |
| CN105770669A (en) | Medicinal preparation for treating colour spots and application thereof | |
| CN103285284B (en) | Medical composition for treating senile vaginitis | |
| CN102430013A (en) | Chinese medicine for treating vitiligo | |
| CN112891485B (en) | Traditional Chinese medicine composition for treating neocoronary pneumonia | |
| TWI693939B (en) | Composition for invigorating kidney and strengthening yang, preparation method and application thereof | |
| CN103191399A (en) | Traditional Chinese medicine composition for treating bronchial asthma in acute-outbreak period | |
| CN103330867B (en) | Preparation method of powder for treating senile vaginitis | |
| CN102319355B (en) | Chinese medicinal formula for treating hyperactivity and preparation method for pills thereof | |
| CN100571725C (en) | A kind of Chinese medicine preparation for the treatment of sciatica | |
| CN102228576B (en) | Chinese patent medicine for treating discoid lupus erythematosus | |
| CN116549595B (en) | Pharmaceutical composition for treating functional dyspepsia of children, preparation and application thereof | |
| CN101108210B (en) | Medicine for treating cervical vertebra disease | |
| CN103735798B (en) | A kind of Chinese medicine composition for the treatment of insufficiency of the spleen damp-heat type recurrent oral ulceration | |
| CN118078935B (en) | Lung tonifying formula for infantile pneumonia recovery period and preparation and application thereof | |
| CN108743850A (en) | A kind of Chinese medicine preparation for nursing period acute mastitis | |
| CN103431277B (en) | Mixed-grain total-nutrition formulation food for traumatic or surgical patients | |
| CN103301374B (en) | Pharmaceutical composition for treating postpartum non-specificity vaginitis | |
| CN106421534A (en) | Traditional Chinese medicinal composition for treating rheumatoid arthritis and preparation method thereof | |
| CN103330896B (en) | Preparation method of powder for treating postpartum nonspecific vaginitis | |
| CN106266985A (en) | A kind of can the pill medicine effectively treating hepatitis B and preparation method thereof | |
| CN105878934A (en) | Brain-invigorating and intelligence-benefiting prescription and brain-invigorating and intelligence-benefiting pillow prepared from prescription |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220527 |
|
| RJ01 | Rejection of invention patent application after publication |