CN114533622A - Blue light prevention repairing agent and blue light prevention repairing aerosol - Google Patents
Blue light prevention repairing agent and blue light prevention repairing aerosol Download PDFInfo
- Publication number
- CN114533622A CN114533622A CN202210061570.6A CN202210061570A CN114533622A CN 114533622 A CN114533622 A CN 114533622A CN 202210061570 A CN202210061570 A CN 202210061570A CN 114533622 A CN114533622 A CN 114533622A
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- extract
- blue light
- blue
- valve
- shower nozzle
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Abstract
The application relates to a blue light-proof repairing agent and a blue light-proof repairing aerosol, and firstly discloses a blue light-proof repairing agent, which specifically comprises the following raw materials in parts by mass: 80-90 parts of water; 2-10 parts of a humectant; 0.1-0.5 part of antibacterial agent; 2.5-8.5 parts of a photorepair component; the photorepair component at least comprises camellia extract, clover extract and calendula extract. The application further discloses prevent blue light repair aerosol, including the bottle, set up in the shower nozzle of bottle with fill in effective component in the bottle, the effective component is aforementioned prevent blue light repairing agent. The application has the effect of low sensitization on the basis of good blue light prevention restoration performance.
Description
Technical Field
The application relates to the field of skin care products, in particular to a blue light prevention repairing agent and a blue light prevention repairing aerosol.
Background
It is known that exposure to sunlight for a long time causes photodamage to the skin, and it is generally known that ultraviolet rays are most harmful to the skin, and therefore, although sunscreen products on the market are complicated at present, the products are mostly harmful to the skin in ultraviolet bands such as UVA and UVB.
In fact, the blue region in visible light is actually very damaging to the skin. Blue light is the wavelength with the shortest wavelength and the highest energy in the visible spectrum, and the penetrating power of the blue light is even higher than that of ultraviolet rays, so that the blue light can also generate damage similar to the ultraviolet rays on skin. Current research shows that blue light can penetrate skin tissue and has phototoxicity, and can affect growth, metabolism, DNA damage of epithelial cells and even cause cell dysfunction and induce apoptosis. It has also been found that blue light exposure has a relationship with photoaging of the skin, age-related diseases and tumorigenesis.
In addition, compared to sunlight, most consumers now have access to various artificial light sources and display devices, such as LED lamps, computer monitors, mobile phones, etc., which can generate a large amount of blue light, causing severe damage to the skin. At present, for part of the consumer population, the effect of blue light on skin is even much greater than that of ultraviolet light because of less exposure to sunlight over a long period of time to various types of electronic devices that produce blue light.
With the understanding of people about the blue light hazard, the protection requirement for blue light is inevitably increased explosively, and on the basis, blue light resistant cosmetics are also inevitably another hot point of light protection cosmetics. At present, most of the main active ingredients of the blue light resistant products are chemically synthesized, and although the chemically synthesized active ingredients have good blue light resistant performance, the chemically synthesized active ingredients often have certain sensitization and are not suitable for sensitive skin.
Disclosure of Invention
In order to improve the problem that the sensitization of the existing common blue-light-proof cosmetics is stronger, the application provides a blue-light-proof repairing agent and a blue-light-proof repairing aerosol.
The application provides a prevent blue light repairing agent and prevent blue light repair aerosol adopts following technical scheme:
in a first aspect, the application provides a blue light-proof repairing agent, which adopts the following technical scheme:
the blue-light-proof repairing agent comprises the following raw materials in parts by mass:
the photorepair component at least comprises camellia extract, clover extract and calendula extract.
By adopting the technical scheme, the alfalfa flower extract has specific absorption under the blue light wavelength of 400 nm and 500nm, and can prevent the irradiation of the blue light in sunlight, display equipment, LED lamps and the like to the skin. The alfalfa flower extract has good antioxidation, and free radicals are eliminated through an ROS signal channel, so that skin injury is repaired.
The main active ingredients in the calendula extract are carotenoid compounds, polysaccharides, flavonol and terpenoids and the like, wherein the flavonol can quench free radicals and filter harmful blue light, so that the damage of the blue light to the skin is reduced.
The camellia extract has anti-allergic and anti-inflammatory effects, and can repair the damage that skin receives the blue light, therefore, the camellia extract is synergistic with alfalfa flower extract, calendula extract, reduces the damage of blue light to skin through straining the blue light on the one hand, repairs the damage that skin received the blue light on the one hand, thereby reduces the damage of blue light to skin.
Because the photorepair components are all plant-derived extracts, the sensitization is lower, and for example, the camellia extract has even further anti-sensitization and anti-inflammation and skin repair effects, so that the sensitization of some inevitable additives in the system can be reduced.
Optionally, the humectant is one or more of 1, 3-butanediol, glycerol, betaine, hyaluronic acid, and collagen.
By adopting the technical scheme, the moisture content of the skin has great influence on the state of the skin, and a large amount of moisture is needed no matter the damage of the blue light to the skin is prevented or the damage of the skin after the blue light irradiation is repaired, so that the reasonable compounding of the humectant has important influence on the blue light prevention effect of the system.
Optionally, the humectant is 1, 3-butanediol, glycerin, betaine and hyaluronic acid according to a mass ratio of (1-5): (1-5): (1-3): (1-3).
By adopting the technical scheme, the 1, 3-butanediol, the glycerol and the betaine are common moisturizing components in cosmetics, and the hyaluronic acid is further added because the hyaluronic acid is an important component of the skin and the skin has a good absorption effect on the hyaluronic acid, so that the absorption rate of the whole moisturizing agent can be improved and the moisturizing effect of the skin can be improved. However, the addition amount of hyaluronic acid is not too large, and the viscosity of hyaluronic acid is high, so that the viscosity of the whole system is too high after the hyaluronic acid is excessively added, and the hyaluronic acid cannot be prepared into a spray formulation. And the inventor finds that the mixture with specific composition and proportion can obtain obviously better moisturizing effect as the moisturizing agent.
Optionally, the antibacterial agent is one or more of coconut oil, panthenol, a herba lysimachiae extract and a honeysuckle extract.
By adopting the technical scheme, compared with the common antibacterial preservatives such as butyl p-hydroxybenzoate, sorbic acid, benzoic acid, p-hydroxybenzoate and the like, the coconut oil extract, the desmodium extract and the honeysuckle extract are plant source components, so that the components are safer, and the allergenicity is lower.
Coconut oil is rich in active substances such as lauric acid, palmitic acid, caprylic acid and the like. Caprylic acid, lauric acid and the like have certain antibacterial properties, wherein the lauric acid is a safe and efficient broad-spectrum bactericide and can inhibit HIV (human immunodeficiency virus), cytomegalovirus, herpes virus, cold virus and a large number of bacteria and protozoa. The antibacterial effect is not affected by pH, and compared with sorbic acid, benzoic acid and p-hydroxybenzoate, the antibacterial effect is better and safer. However, lauric acid easily breaks the sebum membrane and lowers the moisture-retaining and water-retaining ability of the skin, and therefore, the amount of coconut oil added needs to be strictly controlled.
Panthenol, also known as previtamin B5, can stimulate epidermal cells, promote growth, and permeate skin stratum corneum, has the effect of protecting skin barrier, and can resist external stimulation after being combined with amino acids, thereby greatly reducing skin sensitivity. In addition, panthenol can promote wound healing, and has anti-inflammatory and antibacterial effects.
The herba lysimachiae extract has a wider antibacterial spectrum and a better antibacterial effect, and the minimum antibacterial concentration of the herba lysimachiae extract is smaller, which indicates that the herba lysimachiae extract can obtain a better antibacterial effect under a smaller concentration.
The flos Lonicerae extract contains chlorogenic acid and ketone compounds, such as isochlorogenic acid, neochlorogenic acid, and flavonoids. Chlorogenic acid and flavonoids have been proved to have remarkable bacteriostatic action, and the honeysuckle extract is used as an antibacterial agent, so that the sensitization is low and the safety is higher.
Optionally, the antibacterial agent is coconut oil, panthenol and a lysimachia christinae hance extract according to a mass ratio of 1: (0.5-1): (2-3).
By adopting the technical scheme, the inventor finds that the types and the proportion of the antibacterial agents need to be strictly controlled, and antagonism exists even among some plant-derived antibacterial agents, for example, if the elsholtzia extract and the lysimachia christinae hance extract are used in a compounding way, the synergistic interaction effect cannot be achieved, and the minimum antibacterial concentration is even improved, which shows that the antibacterial effects of the elsholtzia extract and the lysimachia christinae hance extract have antagonism.
Specifically, the inventors found that, compared to the use of coconut oil, panthenol or herba lysimachiae extract alone as the antibacterial agent, the ratio of coconut oil, panthenol and herba lysimachiae extract in terms of mass ratio is 1: (0.5-1): when the mixture in the step (2-3) is used as an antibacterial agent, the antibacterial effect of the system is obviously improved, which shows that the coconut oil and the lysimachia christinae hance have a synergistic antibacterial effect under a specific compounding ratio.
In addition, even if the addition amount of coconut oil is strictly controlled, the addition of coconut oil can damage the sebum membrane of the skin, thereby reducing the moisture retention and water locking capacity of the skin. After the coconut oil and the panthenol are compounded for use, the panthenol can protect the skin barrier and reduce the influence of the coconut oil on the skin, so that the sensitization of the skin is reduced on the basis that the system has a good antibacterial effect.
Optionally, the photorepair component further comprises one or more of p-xylylene dicamphor sulfonic acid, rutin, tetrandra root extract, purslane extract, gentian extract, chamomile extract, opuntia ficus-indica stem extract, dandelion extract, dendrobium nobile extract, peach resin extract, oat kernel oil, sage extract, kava root extract, and gardenia flower extract.
By adopting the technical scheme, the inventor finds that the display parts of various electronic equipment can emit ultraviolet rays which are divided into UVA, UVB and UVC, wherein the UVA with the longest wavelength easily penetrates deep into the skin deep layer to damage the dermis layer of the skin, so that the skin is aged, and therefore, in order to reduce the damage of the ultraviolet rays to the skin, various plant extracts can be compounded to improve the photoprotective effect of the system.
Generally, the photorepair component can be selected according to actual production requirements, however, the inventors have unexpectedly found that when the photorepair component comprises p-xylylene dicamphor sulfonic acid, the overall effect of the system is better.
Firstly, p-xylylene dicamphor sulfonic acid, also called Maifanin filtering ring, is one of the most effective UVA sunscreen components at present, and the maximum protective wave band can reach 344nm, so that the protective film has good protective effect on the UVA wave band with the greatest damage to the skin in ultraviolet rays.
And secondly, the antibacterial and anticorrosive performance of the blue light-proof repairing agent is obviously improved, probably because glycerin in the system reacts with lauric acid in coconut oil to generate an esterified substance under the catalysis of p-xylylene dicamphor sulfonic acid, and the antibacterial performance of the esterified substance is superior to that of the lauric acid, so that the finally obtained blue light-proof repairing agent has remarkably better antibacterial and anticorrosive performance.
Furthermore, the dispersibility and the dispersion stability of the blue light prevention repairing agent are also obviously improved, probably because the p-xylylene dicamphor sulfonic acid can also catalyze the reaction of 1, 3-butanediol in a system and caprylic acid in coconut oil to form 1, 3-butanediol caprylate, and the ester compound has good dissolving capacity and dispersing capacity for common UV (ultraviolet) sun-screening agents, so that the dispersion stability of each component in the system can be greatly improved, and the ester compound has a difficult sensitive effect on sensitive muscles, and is particularly suitable for products such as sun-screening, photo-repairing and the like.
In a second aspect, the present application provides a blue light prevention repair aerosol, which adopts the following technical scheme:
the anti-blue-light repair aerosol comprises a bottle body, a spray head arranged on the bottle body and effective components filled in the bottle body, wherein the effective components are the anti-blue-light repair agent.
By adopting the technical scheme, the anti-blue-light repairing agent is prepared into an aerosol dosage form, so that the anti-blue-light repairing agent is convenient to use, and various plant source extracts in the anti-blue-light repairing agent are not easy to oxidize and deteriorate due to the isolation of the anti-blue-light repairing agent from the outside, and the possibility of skin sensitization reaction caused by spraying rotten and deteriorated substances on the skin is further reduced.
Optionally, be equipped with on the shower nozzle be used for with active ingredient atomizing spun nozzle, the roof of shower nozzle is established to the inclined plane, be equipped with the piece of keeping in on the shower nozzle, the piece of keeping in is including keeping in box and the flexible pipe of elasticity, the box of keeping in fix set up in the roof of shower nozzle, seted up on the shower nozzle be used for with the inside runner of shower nozzle with the through-hole that the box of keeping in is linked together, the through-hole is located the shower nozzle is kept away from one side of nozzle, seted up on the shower nozzle be used for with the inside runner of shower nozzle with the infusion passageway that the box of keeping in is linked together, the infusion passageway is located the shower nozzle is close to one side of nozzle, flexible pipe one end opening of elasticity just flexible pipe's open end fixed connection in the roof of the box of keeping in, flexible pipe with the box of keeping in is linked together.
By adopting the technical scheme, the high-pressure driving gas is arranged in both the unitary aerosol and the binary aerosol, so that the principle of the aerosol product determines that the pressure of the effective components in the flow passage of the spray head is still greater than the external atmospheric pressure after the effective components in the spray head are sprayed out by pressing the spray head. Therefore, after the aerosol product is used, a small amount of effective components often overflow from a nozzle of a spray head, so that the bottle body is easily polluted, more importantly, the effective components overflowing from the nozzle are easily oxidized and deteriorated, and after the oxidized and deteriorated effective components are sprayed on the skin, the allergic reaction of the skin is easily caused.
Specifically, set up the piece of keeping in on the shower nozzle, use the aerosol after, thereby the flexible pipe of elasticity can resume deformation and extract the air in the box of keeping in, consequently form the negative pressure in the box of keeping in and extract the effective component in the shower nozzle runner through-hole and infusion passageway to store the effective component of extraction in the box of keeping in. When the aerosol is reused, the air in the elastic telescopic pipe can be pressed into the temporary storage box by pressing the elastic telescopic pipe, so that the effective components in the temporary storage box are pumped into the flow channel of the spray head again by compressed air. Through keeping in the active ingredient to in the shower nozzle runner, can greatly reduced the use back active ingredient spill over and rotten possibility of rotting.
In addition, the through hole and the infusion channel are specially arranged, so that the effective components in the flow channel of the spray head, particularly the effective components close to the nozzle, can be extracted and temporarily stored; when the effective components in the temporary storage box are pumped, the top wall of the spray head is obliquely arranged, so that the effective components are only pumped into the flow channel of the side, far away from the spray nozzle, of the spray head through the through hole to discharge air in the flow channel of the side, near the spray nozzle, of the spray head, the possibility of overflow after the effective components are pumped into the flow channel of the side, near the spray nozzle, of the spray head can be reduced, and the possibly rotten and deteriorated effective components temporarily reserved at the spray nozzle can be blown down through the discharged air.
Optionally, a pressing assembly is further arranged on the spray head, the pressing assembly comprises a connecting elastic sheet and a pressing plate, the connecting elastic sheet is fixedly connected to one side, close to the spray nozzle, of the spray head, one end of the pressing plate is connected with the connecting elastic sheet, and the other end of the pressing plate is connected with the elastic telescopic pipe.
Through adopting above-mentioned technical scheme, the clamp plate can shield the flexible pipe of elasticity that is easy to damage, and connects the shell fragment and can restore to the throne through the flexible pipe of clamp plate help elasticity to the active ingredient in the better extraction shower nozzle runner.
Optionally, a first check valve is arranged in the infusion channel, a second check valve is arranged in the through hole, the first check valve includes a first valve ring, a first elastic member and a first valve plate, the first valve ring and the first elastic member are both fixedly connected to the inner wall of the infusion channel, the first elastic member is located on one side of the first valve ring close to the temporary storage box, the first valve plate is arranged between the first valve ring and the first elastic member, and the first valve plate is pushed by the first elastic member to abut against the first valve ring; the second one-way valve comprises a second valve ring, a second elastic piece and a second valve piece, the second valve ring and the second elastic piece are fixedly connected to the inner wall of the through hole, the second elastic piece is located on one side, away from the temporary storage box, of the second valve ring, the second valve piece is arranged between the second valve ring and the second elastic piece, and the second valve piece is pushed by the second elastic piece to be tightly abutted to the second valve ring.
Through adopting above-mentioned technical scheme, further set up first check valve in infusion passageway, set up the second check valve in the through-hole, can keep apart the effectual and outside air of effective component in the box of keeping in. When the inside of the temporary storage box is negative pressure, a first check valve in the transfusion channel is opened to extract effective components of a flow passage at the position of the spray head, which is close to the nozzle, into the temporary storage box; when the air pressure in the temporary storage box is higher, the second check valve in the through hole is opened so as to pump the effective components in the temporary storage box into the flow channel of the spray head far away from the spray nozzle.
In summary, the present application includes at least one of the following beneficial technical effects:
1. the plant extract is compounded and used as a light repairing component, so that the damage of blue light to skin can be greatly reduced, and on the basis, the plant extract is low in sensitization and suitable for sensitive muscle consumers;
2. by specially compounding the components and the proportion of the humectant, a better transdermal absorption effect can be obtained, so that a good moisturizing effect is obtained, and the blue light prevention effect is further improved;
3. by specific limitation on the composition and the proportion of the antibacterial agent, an obvious synergistic antibacterial effect can be obtained, and compared with the existing common chemically synthesized antibacterial preservative, the antibacterial agent used in the application has low allergenicity;
4. by specially limiting the components and the proportion of the photorepair, the composition can generate synergistic antibacterial and stable dispersing capacity with the components in the antibacterial agent on the basis of further obtaining better photorepair capacity.
Drawings
Fig. 1 is a schematic structural diagram of an overall blue light-proof repair aerosol according to an embodiment of the present application.
Fig. 2 is a cross-sectional view of the overall structure of the blue-light-proof repair aerosol according to the embodiment of the application.
Fig. 3 is a cross-sectional view of a spray head in a blue-light-blocking repair aerosol of an embodiment of the present application.
Fig. 4 is a partially enlarged schematic view of a portion a of fig. 3.
Fig. 5 is a partially enlarged schematic view of a portion B in fig. 3.
Description of reference numerals: 1. a bottle body; 11. a spray head; 12. a nozzle; 2. a temporary storage member; 21. a temporary storage box; 22. an elastic telescopic pipe; 23. a fluid infusion channel; 24. a through hole; 3. a first check valve; 31. a first valve ring; 32. a first elastic member; 33. a flow passage hole; 34. a first valve plate; 4. a second one-way valve; 41. a second valve ring; 42. a second elastic member; 43. a second valve plate; 5. a guide post; 6. a seal ring; 7. a pressing assembly; 71. connecting the elastic sheets; 72. and (7) pressing a plate.
Detailed Description
The present application will be described in further detail with reference to examples, comparative examples and FIGS. 1 to 5.
The sources and performance parameters of the raw materials used in the examples and comparative examples of the present application are given in the following table:
raw material | Performance parameters/brands | Source |
Hyaluronic acid | 40kDa | Jiangsu Baiyao Biotechnology Ltd |
Collagen protein | 1000Da | Hubei Zhenmi Biotechnology Ltd |
Except for the raw materials in the above tables, the raw materials in the embodiments of the present application are all conventionally commercially available unless otherwise specified.
The embodiment of the application discloses a blue light-proof repairing agent and a blue light-proof repairing aerosol.
Example 1
The embodiment of the application firstly discloses a blue light prevention repairing agent, and each compounded blue light prevention repairing agent comprises the following raw materials in parts by mass:
wherein the content of the first and second substances,
the humectant is a mixture of 1, 3-butanediol, glycerol and betaine in equal mass ratio;
the antibacterial agent is butyl p-hydroxybenzoate;
the photorepair component is a mixture of camellia extract, alfalfa flower extract and calendula extract in equal mass ratio.
The embodiment of the application further discloses a blue light prevention repair aerosol, and because the structures of the blue light prevention repair aerosol in the embodiments are completely the same, the structure of the blue light prevention repair aerosol is explained by taking the embodiment 1 as an example.
Referring to fig. 1, the blue light-proof repair aerosol comprises a bottle body 1, active ingredients filled in the bottle body 1, and a spray head 11 installed on the bottle body 1, wherein a nozzle 12 is arranged on the spray head 11 to seal the bottle body 1 and atomize and spray the active ingredients in the bottle body 1, and the active ingredients are the blue light-proof repair agent.
Referring to fig. 1, since various plant extracts in the blue light-proof repairing agent are easily oxidized, deteriorated or decayed, the blue light-proof repairing agent remaining in the nozzle 11 is easily sensitized after being sprayed on the skin after being deteriorated, and therefore, the temporary storage member 2 for isolating and temporarily storing the effective components in the flow channel of the nozzle 11 is arranged on the nozzle 11.
Referring to fig. 1 and 2, the top wall of the head 11 is formed as an inclined surface, and the inclined surface is inclined downward from the nozzles 12 near the head 11 to the nozzles 12 far from the head 11, and the inclined surface forms an inclined platform on the top wall of the head 11, and the temporary storage 2 is mounted on the inclined surface of the head 11.
Referring to fig. 2 and 3, the temporary storage member 2 includes a temporary storage box 21 and an elastic telescopic tube 22, the temporary storage box 21 is fixedly installed on the inclined surface of the spraying head 11, and the top wall of the temporary storage box 21 is horizontally arranged. One end of the elastic extension tube 22 is open, the open end of the elastic extension tube 22 is connected to the top wall of the temporary storage box 21, the elastic extension tube 22 is located at one end of the temporary storage box 21 far away from the nozzle 12, and the elastic extension tube 22 is communicated with the cavity of the temporary storage box 21. By controlling the expansion and contraction of the elastic expansion tube 22, the air pressure in the temporary storage box 21 can be controlled.
Referring to fig. 2 and 3, a liquid feeding channel 23 is formed at one end of the spray head 11 close to the nozzle 12, the liquid feeding channel 23 is used for communicating a flow channel of the spray head 11 close to the nozzle 12 with an internal cavity of the temporary storage box 21, a through hole 24 is formed at one end of the spray head 11 far from the nozzle 12, and the through hole 24 is used for communicating the flow channel of the spray head 11 far from the nozzle 12 with the internal cavity of the temporary storage box 21.
Referring to fig. 3 and 4, a first check valve 3 is arranged in the infusion channel 23, the first check valve 3 includes a first valve ring 31, a first elastic member 32 and a first valve plate 34, the first valve ring 31 and the first elastic member 32 are both fixedly connected to the inner wall of the infusion channel 23, the first valve ring 31 and the first elastic member 32 are both located at one end of the infusion channel 23 close to the temporary storage box 21, the first valve ring 31 and the first elastic member 32 are arranged at intervals along the axial direction of the infusion channel 23, and the first elastic member 32 is located at one side of the first valve ring 31 close to the temporary storage box 21. The first valve plate 34 is in sliding fit with the liquid conveying channel 23 and is located between the first elastic member 32 and the first valve ring 31, and the first valve plate 34 is pressed against the first valve ring 31 under the pushing of the first elastic member 32.
Referring to fig. 3 and 5, a second check valve 4 is disposed in the through hole 24, the second check valve 4 includes a second valve ring 41, a second elastic member 42 and a second valve plate 43, the second valve ring 41 and the second elastic member 42 are both fixedly connected to an inner wall of the through hole 24, the second valve ring 41 and the second elastic member 42 are both located at an end of the through hole 24 away from the temporary storage box 21, the second valve ring 41 and the second elastic member 42 are arranged at intervals in an axial direction of the through hole 24, and the second elastic member 42 is located at a side of the second valve ring 41 away from the temporary storage box 21. The second valve plate 43 is in sliding fit with the through hole 24 and is located between the second elastic member 42 and the second valve ring 41, and the second valve plate 43 is pressed against the second valve ring 41 under the pushing of the second elastic member 42.
Referring to fig. 3, 4 and 5, the guide posts 5 are fixedly arranged on both the side of the first valve plate 34 away from the first valve ring 31 and the side of the second valve plate 43 away from the second valve ring 41, and the guide posts 5 on the first valve plate 34 slidably penetrate through the first elastic member 32 to guide the movement of the first valve plate 34; the guide post 5 of the second valve plate 43 slides through the second elastic member 42 to guide the movement of the second valve plate 43.
Referring to fig. 3, 4 and 5, the first elastic member 32 and the second elastic member 42 are both elastic pieces, the elastic pieces are circular and connected to the peripheral wall of the infusion channel 23 or the through hole 24, three flow channel holes 33 are formed in the elastic pieces, and the three flow channel holes 33 are arranged at equal intervals along the circumferential direction of the elastic pieces.
Referring to fig. 3, 4 and 5, the first valve plate 34 and the second valve plate 43 are circumferentially provided with a seal ring 6 on both sides close to the first valve ring 31 and the second valve ring 41.
When the elastic extension tube 22 is compressed, air in the elastic extension tube 22 is pumped into the temporary storage box 21, the air pressure in the temporary storage box 21 is high, and the second valve plate 43 in the second one-way valve 4 can be pushed, so that a gap is formed between the second valve plate 43 and the second valve ring 41. The effective components temporarily stored in the temporary storage box 21 are pumped into the flow channel of the side of the spray head 11 far away from the spray nozzle 12 through the through hole 24, and air and a small amount of residual effective components in the flow channel of the side of the spray head 11 close to the spray nozzle 12 are discharged.
When the elastic extension tube 22 recovers deformation, the elastic extension tube 22 extracts air in the temporary storage box 21 to form negative pressure in the temporary storage box 21, the negative pressure pushes the first valve plate 34 in the first check valve 3, so that a gap is formed between the first valve plate 34 and the first valve ring 31, and effective components in a flow passage at one side of the spray head 11 close to the spray nozzle 12 are extracted into the temporary storage box 21 through the liquid conveying passage 23, and the effective components flow and are temporarily stored along the inclined surface of the spray head 11.
Referring to fig. 1 and 2, a pressing assembly 7 for pushing the elastic extension tube 22 to deform is disposed on the spray head 11, the pressing assembly 7 includes a connecting elastic piece 71 and a pressing plate 72, the connecting elastic piece 71 is fixedly connected to a top wall of the spray head 11, the connecting elastic piece 71 is located at one end of the spray head 11 close to the nozzle 12, one end of the pressing plate 72 is connected to one end of the connecting elastic piece 71 far away from the spray head 11, and the other end of the pressing plate 72 is connected to one end of the elastic extension tube 22 far away from the spray head 11. The pressing plate 72 is used for pressing the elastic extension tube 22 to deform, and the connecting elastic piece 71 drives the elastic extension tube 22 to recover deformation through the pressing plate 72.
Examples 2 to 3
The difference between the examples 2-3 and the example 1 is that each compounded part of the blue-light-proof repairing agent comprises different raw materials in parts by mass, and the raw materials are represented as the following table:
examples 4 to 8
Examples 4 to 8 are different from example 1 in that the humectant has different compositions and ratios, and the compositions and ratios of the respective materials in the humectant are shown in the following table:
examples 9 to 13
Examples 9-13 differ from example 8 in the composition and proportions of the antimicrobial agent, which are given in the following table:
examples 14 to 16
Examples 14-16 differ from example 13 in the composition and proportions of the photorepair component, and the compositions and proportions of the materials in the photorepair component are given in the following table:
example 17
Example 17 differs from example 14 in that coconut oil is replaced in the antibacterial agent with an equal mass of honeysuckle extract.
Example 18
Example 18 differs from example 14 in that the glycerin is replaced in the humectant by an equal mass of betaine.
Example 19
Example 18 differs from example 14 in that the humectant replaces 1, 3-butanediol with an equal mass of betaine.
Comparative example
Comparative example 1
Comparative example 1 differs from example 1 in that the photorepair component is Merck, Germany Balance Blue。
Performance detection method and detection data
First, prevent the blue light effect
Although blue light is generally considered as high-energy visible light with the wavelength of 400-500nm, it is found that blue light harmful to skin is blue-violet light with the wavelength of about 400-450nm, and the most representative wavelength of blue-violet light is 440nm, so that only the absorption effect of blue-violet light with the harmful wavelength of 440nm is detected in the present application, and the specific detection method is as follows:
taking the blue-light-proof repairing agent obtained by compounding in each embodiment or comparative example, and preparing a 20 wt% solution with deionized water to obtain a test sample. The absorbance of the sample at 450nm is tested by using an ultraviolet-visible spectrophotometer, and the higher the absorbance is, the better the absorption effect of the sample on the 440nm blue-violet light is, and the better the blue light prevention effect is.
Second, sensitization
The sensitization test was carried out using the blue-light-blocking repair agent prepared in each example or comparative example as a sample, and was carried out in accordance with regulations in the technical specifications for cosmetic safety (2015), hereinafter referred to as "specifications", and related specifications of skin irritation/corrosion tests. The experimental animals are guinea pigs weighing about 350g to 450g, and each group of experimental animals is 10 animals with male and female halves. The specific operation steps are carried out according to relevant regulations in the Standard 5.3 acute skin irritation test step, specifically, the samples are removed from the experimental animals after being coated for 4 hours, skin reactions are observed for 1, 24, 48 and 72 hours after the samples are removed, skin irritation intensity grading is carried out according to skin states and skin irritation reactions and according to integral, and grading rules and skin irritation intensity judgment standards refer to relevant records in the result evaluation of the Standard 5.4.3.
III, stability
Taking the blue-light-proof repairing agent compounded in each embodiment or comparative example as a sample, putting the sample into a sterilized container with a rubber plug, and dispersing for 4min by microwave oscillation with the microwave power of 60W to obtain the sample. And then putting the sample into an oven at 45 ℃ for heat preservation and storage for 30d, then putting the sample into a refrigerator at 0 ℃ for heat preservation and storage for 30d, then taking the sample out of the oven at 25 ℃ for overnight recovery, observing the change condition of the properties of the sample and grading, wherein the higher the stability grade is, the better the stability is.
IV, antibacterial property
Since no effective preservative and antibacterial efficacy test method is described in technical specifications for cosmetic safety (2015), the application refers to ISO 11930:2019, evaluation of cosmetic microbiology and preservative performance, issued by international organization for standardization, for testing preservative and antibacterial performance.
Staphylococcus aureus (Staphylococcus aureus) [ CMCC (B)26003]Escherichia coli (CMCC (B)44102]Pseudomonas aeruginosa [ CMCC (B)10104]Candida albicans (CMCC (F)) 98001]And Aspergillus niger (CMCC (F)98003]The strains in 5 were used as test strains, and the preparation of the suspensions was carried out according to the protocol ISO 11930:2019, and the number of bacteria contained in the suspensions was about 1X 108CFU/mL。
Taking the blue-light-proof repairing agent compounded in each embodiment or comparative example as a sample, putting the sample into a sterilization container, adding bacterial suspension with the volume fraction of 1%, storing the sample at 25 ℃ in a dark place for 24 hours, taking 1mL of mixed solution, diluting the mixed solution, culturing the diluted mixed solution in an agar culture medium for 48 hours, and measuring the total number of bacterial colonies at the culture temperature of 36 ℃ to calculate the sterilization rate.
The above performance test data are shown as the following table:
conclusion
By comparing the data of example 1 and comparative example 1, it can be shown that compared with the conventional commercially available photorepair component on the market at present, the plant source extract in the application is compounded and used as the photorepair agent, so that the allergenicity of the system can be reduced on the basis of ensuring the blue light prevention repairing effect. The allergen in example 1 should be the antimicrobial agent butyl paraben, which is a highly irritating compound, although it has good antimicrobial preservative effect.
Comparing the data of examples 1 and 4 to 8, it can be concluded that the specific use of a mixture of 1, 3-butanediol, glycerol, betaine, and hyaluronic acid in a certain mass ratio as a humectant can significantly reduce the sensitization of the system, probably because the specific humectant can achieve a better moisturizing effect, thereby enabling the anti-blueing and photorepair effects of the system to take a better effect.
It can be concluded from the comparison of the data of examples 8-10 that even if butyl paraben is replaced by a mixture of extracts of plant origin as an antibacterial agent, the sensitization of the system is still high, probably because, although the amount of added coconut oil in the system has been strictly controlled, the nature of coconut oil itself determines that coconut oil destroys the sebum membrane on the skin surface, thereby causing a decrease in the ability of the skin to moisturize and lock water, etc., and the skin tends to become more sensitive.
It can be seen from the comparison of the data of examples 8 and 11 to 13 that the sensitization of the system can be greatly reduced by further adding panthenol to coconut oil, probably because panthenol can play a role in repairing the skin and can also permeate the horny layer of the skin and combine with amino acid to resist external stimulation, thereby greatly improving the anti-sensitization of the skin itself. Therefore, when coconut oil is added to the system, a certain amount of panthenol is added simultaneously, so that the sensitization of the system can be reduced.
It can be seen from comparing the data of examples 13-16 that the blue light protection effect of the system is not greatly affected by the addition of p-xylylene dicamphor sulfonic acid to the photorepair component (the anti-uv effect of the system is not detected because the protective effect of p-xylylene dicamphor sulfonic acid to UVA is known), and that the sensitization to p-xylylene dicamphor sulfonic acid is also low. But after the p-xylylene dicamphor sulfonic acid is added, the stability and the antibacterial and antiseptic properties of the system are obviously improved. This demonstrates the synergistic antimicrobial and stability enhancing effect of p-xylylene dicamphor sulfonic acid with certain materials in the system.
Comparing the effects of example 14 and example 17, it can be seen that, based on the addition of p-xylylene dicamphor sulfonic acid to the photorepair component, the antimicrobial and antiseptic effects and stability of the system are significantly reduced if coconut oil is not added to the antimicrobial agent. This demonstrates the synergistic antibacterial and stability enhancing effect between terephthalylidenedicamphor sulfonic acid and coconut oil.
Comparing the effects of example 14 and example 18, it can be seen that, on the basis of adding p-xylylene dicamphor sulfonic acid to the photo-repair component and adding coconut oil to the antimicrobial agent, if glycerin is not added to the system, the stability of the system is not changed significantly, but the antimicrobial and antiseptic properties of the system are reduced significantly. This is probably due to the synergistic antimicrobial preservative effect between para-xylylene dicamphor sulfonic acid coco and glycerin.
Comparing the effects of example 14 and example 19, it can be seen that, on the basis of adding p-xylylene dicamphor sulfonic acid to the photo-repair component and adding coconut oil to the antimicrobial agent, if 1, 3-butanediol is not added to the system, the antimicrobial and antiseptic properties of the system are not changed significantly, but the stability of the system is significantly reduced. This is probably due to the synergistic stability-enhancing effect between coco p-xylylenedicamphor sulfonate and 1, 3-butanediol.
The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.
Claims (10)
2. The blue-light preventing repair agent according to claim 1, wherein: the humectant is one or more of 1, 3-butanediol, glycerol, betaine, hyaluronic acid and collagen.
3. The blue-light preventing repair agent according to claim 1, wherein: the humectant is prepared from 1, 3-butanediol, glycerol, betaine and hyaluronic acid according to the mass ratio of (1-5): (1-5):
(1-3): (1-3).
4. The blue-light preventing repair agent according to claim 1, wherein: the antibacterial agent is one or more of coconut oil, panthenol, herba Lysimachiae Christinae extract and flos Lonicerae extract.
5. The blue-light preventing repair agent according to claim 1, wherein: the antibacterial agent is coconut oil, panthenol and a lysimachia christinae hance extract according to a mass ratio of 1: (0.5-1): (2-3).
6. The blue-light preventing repair agent according to claim 1, wherein: the photorepair component also comprises one or more of p-xylylene dicamphor sulfonic acid, rutin, radix Stephaniae Japonicae extract, herba Portulacae extract, radix Gentianae extract, flos Chrysanthemi extract, caulis Opuntiae Dillenii stem extract, herba Taraxaci extract, herba Dendrobii extract, peach resin extract, oat kernel oil, herba Salvia officinalis extract, radix Piper methysticum extract, and Gardenia jasminoides extract.
7. A blue light prevention repair aerosol is characterized in that: comprises a bottle body (1), a spray head (11) arranged on the bottle body (1) and an effective component filled in the bottle body (1), wherein the effective component is the blue-light-proof repairing agent as defined in any one of claims 1-6.
8. The anti-blue-light repair aerosol as claimed in claim 7, wherein: be equipped with on shower nozzle (11) be used for with active ingredient atomizing spun nozzle (12), the roof of shower nozzle (11) is established to the inclined plane, be equipped with on shower nozzle (11) and keep in piece (2), keep in piece (2) including keeping in box (21) and flexible pipe of elasticity (22), keep in box (21) fixed set up in the roof of shower nozzle (11), offer on shower nozzle (11) be used for with through-hole (24) that the inside runner of shower nozzle (11) and box (21) are linked together keep in, through-hole (24) are located one side that nozzle (12) were kept away from to shower nozzle (11), offer on shower nozzle (11) be used for with the inside runner of shower nozzle (11) with the infusion passageway (23) that box (21) are linked together keep in, infusion passageway (23) are located shower nozzle (11) are close to one side of nozzle (12), one end of the elastic telescopic pipe (22) is opened, the opening end of the elastic telescopic pipe (22) is fixedly connected to the top wall of the temporary storage box (21), and the elastic telescopic pipe (22) is communicated with the temporary storage box (21).
9. The anti-blue light repair aerosol of claim 8, wherein: the spray head (11) is further provided with a pressing assembly (7), the pressing assembly (7) comprises a connecting elastic sheet (71) and a pressing plate (72), the connecting elastic sheet (71) is fixedly connected to one side, close to the spray nozzle (12), of the spray head (11), one end of the pressing plate (72) is connected with the connecting elastic sheet (71), and the other end of the pressing plate (72) is connected with the elastic extension tube (22).
10. The anti-blue-light repair aerosol as claimed in claim 9, wherein: a first one-way valve (3) is arranged in the infusion channel (23), a second one-way valve (4) is arranged in the through hole (24), the first one-way valve (3) comprises a first valve ring (31), a first elastic piece (32) and a first valve plate (34), the first valve ring (31) and the first elastic piece (32) are fixedly connected to the inner wall of the infusion channel (23), the first elastic piece (32) is located on one side, close to the temporary storage box (21), of the first valve ring (31), the first valve plate (34) is arranged between the first valve ring (31) and the first elastic piece (32), and the first valve plate (34) is tightly abutted to the first valve ring (31) under the pushing of the first elastic piece (32); the second one-way valve (4) comprises a second valve ring (41), a second elastic piece (42) and a second valve plate (43), the second valve ring (41) and the second elastic piece (42) are fixedly connected to the inner wall of the through hole (24), the second elastic piece (42) is located on one side, away from the temporary storage box (21), of the second valve ring (41), the second valve plate (43) is arranged between the second valve ring (41) and the second elastic piece (42), and the second valve plate (43) is pressed against the second valve ring (41) under the pushing of the second elastic piece (42).
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116672296A (en) * | 2023-08-01 | 2023-09-01 | 珠海远大美业生物科技有限公司 | Compound plant extract with soothing and repairing effects, and preparation method and application thereof |
Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060165644A1 (en) * | 2002-08-14 | 2006-07-27 | Fancl Corporation | Cosmetics |
US20130195925A1 (en) * | 2011-11-03 | 2013-08-01 | Vaskin, Llc | Anti aging application and method for treating aging |
CN110236965A (en) * | 2019-07-23 | 2019-09-17 | 广州市科能化妆品科研有限公司 | Blue light resistant skin care cosmetic and preparation method thereof |
CN110368338A (en) * | 2019-08-23 | 2019-10-25 | 三门华迈化工产品有限公司 | Aerosol with epidermis repair function |
CN110575410A (en) * | 2019-09-16 | 2019-12-17 | 安婕妤化妆品科技股份有限公司 | Cosmetic containing blue light-shielding component |
CN111494261A (en) * | 2020-04-24 | 2020-08-07 | 上海珈凯生物科技有限公司 | Application of medicago sativa extract in product with blue light protection effect and preparation method of medicago sativa extract |
CN111557875A (en) * | 2020-06-02 | 2020-08-21 | 华熙生物科技股份有限公司 | Skin care composition for resisting light pollution and light injury and preparation method and application thereof |
CN111631969A (en) * | 2020-07-08 | 2020-09-08 | 华南农业大学 | Repair liquid with blue light resisting effect and cosmetic thereof |
CN111686069A (en) * | 2020-06-30 | 2020-09-22 | 上海林清轩生物科技有限公司 | Blue-light-resistant repair composition containing camellia extract and application thereof |
CN112076119A (en) * | 2020-08-27 | 2020-12-15 | 诺德睿行(广州)电子商务有限公司 | Camellia flower water emulsion with moisturizing and oxidation resisting functions |
CN112294667A (en) * | 2020-11-09 | 2021-02-02 | 西安润玉医疗科技有限公司 | Composition with broad-spectrum light protection effect and application thereof |
CN112515981A (en) * | 2020-11-24 | 2021-03-19 | 湖南御家化妆品制造有限公司 | Light absorption core-shell structure particle and preparation method and application thereof |
CN112870122A (en) * | 2021-01-29 | 2021-06-01 | 科丝美诗(中国)化妆品有限公司 | High-stability nano emulsion with light protection effect and preparation method thereof |
US20210161788A1 (en) * | 2019-11-29 | 2021-06-03 | Taiwan Ac Scientific Inc. | Anti-Blue Light Dermal Topical Composition and Applications Thereof |
WO2021218039A1 (en) * | 2020-04-29 | 2021-11-04 | 上海林清轩生物科技有限公司 | Biomimetic and camellia extract-containing skin barrier repair composition and application thereof |
CN217228675U (en) * | 2022-01-19 | 2022-08-19 | 艾依诺科技有限公司 | Blue light prevention spray |
-
2022
- 2022-01-19 CN CN202210061570.6A patent/CN114533622B/en active Active
Patent Citations (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060165644A1 (en) * | 2002-08-14 | 2006-07-27 | Fancl Corporation | Cosmetics |
US20130195925A1 (en) * | 2011-11-03 | 2013-08-01 | Vaskin, Llc | Anti aging application and method for treating aging |
CN110236965A (en) * | 2019-07-23 | 2019-09-17 | 广州市科能化妆品科研有限公司 | Blue light resistant skin care cosmetic and preparation method thereof |
CN110368338A (en) * | 2019-08-23 | 2019-10-25 | 三门华迈化工产品有限公司 | Aerosol with epidermis repair function |
CN110575410A (en) * | 2019-09-16 | 2019-12-17 | 安婕妤化妆品科技股份有限公司 | Cosmetic containing blue light-shielding component |
US20210161788A1 (en) * | 2019-11-29 | 2021-06-03 | Taiwan Ac Scientific Inc. | Anti-Blue Light Dermal Topical Composition and Applications Thereof |
CN111494261A (en) * | 2020-04-24 | 2020-08-07 | 上海珈凯生物科技有限公司 | Application of medicago sativa extract in product with blue light protection effect and preparation method of medicago sativa extract |
WO2021218039A1 (en) * | 2020-04-29 | 2021-11-04 | 上海林清轩生物科技有限公司 | Biomimetic and camellia extract-containing skin barrier repair composition and application thereof |
CN111557875A (en) * | 2020-06-02 | 2020-08-21 | 华熙生物科技股份有限公司 | Skin care composition for resisting light pollution and light injury and preparation method and application thereof |
CN111686069A (en) * | 2020-06-30 | 2020-09-22 | 上海林清轩生物科技有限公司 | Blue-light-resistant repair composition containing camellia extract and application thereof |
CN111631969A (en) * | 2020-07-08 | 2020-09-08 | 华南农业大学 | Repair liquid with blue light resisting effect and cosmetic thereof |
CN112076119A (en) * | 2020-08-27 | 2020-12-15 | 诺德睿行(广州)电子商务有限公司 | Camellia flower water emulsion with moisturizing and oxidation resisting functions |
CN112294667A (en) * | 2020-11-09 | 2021-02-02 | 西安润玉医疗科技有限公司 | Composition with broad-spectrum light protection effect and application thereof |
CN112515981A (en) * | 2020-11-24 | 2021-03-19 | 湖南御家化妆品制造有限公司 | Light absorption core-shell structure particle and preparation method and application thereof |
CN112870122A (en) * | 2021-01-29 | 2021-06-01 | 科丝美诗(中国)化妆品有限公司 | High-stability nano emulsion with light protection effect and preparation method thereof |
CN217228675U (en) * | 2022-01-19 | 2022-08-19 | 艾依诺科技有限公司 | Blue light prevention spray |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116672296A (en) * | 2023-08-01 | 2023-09-01 | 珠海远大美业生物科技有限公司 | Compound plant extract with soothing and repairing effects, and preparation method and application thereof |
CN116672296B (en) * | 2023-08-01 | 2023-11-03 | 珠海远大美业生物科技有限公司 | Compound plant extract with soothing and repairing effects, and preparation method and application thereof |
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