CN114469821A - Efficient repairing anti-aging skin care product and preparation method thereof - Google Patents
Efficient repairing anti-aging skin care product and preparation method thereof Download PDFInfo
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- CN114469821A CN114469821A CN202210333249.9A CN202210333249A CN114469821A CN 114469821 A CN114469821 A CN 114469821A CN 202210333249 A CN202210333249 A CN 202210333249A CN 114469821 A CN114469821 A CN 114469821A
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- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 238000004519 manufacturing process Methods 0.000 title description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 18
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 12
- 230000003020 moisturizing effect Effects 0.000 claims abstract description 8
- 241000220317 Rosa Species 0.000 claims abstract description 7
- 239000008169 grapeseed oil Substances 0.000 claims abstract description 7
- 239000006188 syrup Substances 0.000 claims abstract description 7
- 235000020357 syrup Nutrition 0.000 claims abstract description 7
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims abstract description 7
- 229960000401 tranexamic acid Drugs 0.000 claims abstract description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 6
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 6
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 6
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 6
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229960000458 allantoin Drugs 0.000 claims abstract description 6
- 229960001631 carbomer Drugs 0.000 claims abstract description 6
- 150000002500 ions Chemical class 0.000 claims abstract description 6
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 6
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 6
- 239000000126 substance Substances 0.000 claims description 20
- 238000010438 heat treatment Methods 0.000 claims description 15
- 239000003921 oil Substances 0.000 claims description 13
- 235000019198 oils Nutrition 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000000203 mixture Substances 0.000 claims description 12
- 230000001804 emulsifying effect Effects 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 4
- 108030001720 Bontoxilysin Proteins 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 229940053031 botulinum toxin Drugs 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010031318 Vitronectin Proteins 0.000 description 1
- 102100035140 Vitronectin Human genes 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005282 brightening Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- -1 hexapeptide Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses an efficient repairing anti-aging skin care product and a preparation method thereof, wherein the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass: 55-75 parts of anhydrous ions, 6-10 parts of glycerol, 1.5-3.2 parts of double-effect moisturizing factors, 0.82-0.86 part of tranexamic acid, 2-4 parts of rose syrup, 0.13-0.17 part of hexapeptide, 2-8 parts of grape seed oil, 0.6-0.8 part of vitriol, 0.11-0.13 part of acetylated hexapeptide, 0.1-0.3 part of allantoin, 0.08-0.12 part of carbomer, 0.16-0.20 part of sodium hyaluronate and 0.15-0.17 part of triethanolamine.
Description
Technical Field
The invention relates to an anti-aging skin care product, in particular to an efficient repairing anti-aging skin care product and a preparation method thereof, belonging to the technical field of skin care products.
Background
The growth process of people is a gradually changing process from young to old, and the skin of people is the same, and the skin of people is gradually aged with the age. For women, people want to keep their youth, and therefore some anti-aging ingredients are used to delay aging.
The anti-aging skin care products on the market also have a plurality of anti-aging effects of common skin, the anti-aging effect on the skin is increased by adding the botulinum toxin to a part of the skin care products, although the anti-aging effect is good, the botulinum toxin has toxicity and is only suitable for being used in a short time, and the skin can be oxidized after being used for a long time, so that the problems of depression on the surface of the skin, even fleck, pox and the like are caused.
Disclosure of Invention
The invention aims to provide an efficient repairing anti-aging skin care product and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
as a preferred technical scheme, the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
as a preferred technical scheme, the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
as a preferred technical scheme, the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
as a preferred technical scheme, the preparation method of the efficient repairing anti-aging skin care product comprises the following steps:
the method comprises the following steps: firstly, 55-75 parts of anhydrous ions, 6-10 parts of glycerol, 1.5-3.2 parts of double-effect moisturizing factors, 0.82-0.86 part of tranexamic acid, 2-4 parts of rose syrup, 0.13-0.17 part of hexapeptide, 2-8 parts of grape seed oil, 0.6-0.8 part of vitriol, 0.11-0.13 part of acetylated hexapeptide, 0.1-0.3 part of allantoin, 0.08-0.12 part of carbomer, 0.16-0.20 part of sodium hyaluronate and 0.15-0.17 part of triethanolamine are carried out according to the mass parts of the following raw material formula;
step two: respectively placing the oil phase substance and the water phase substance in the step one in two crucibles for dissolving, respectively stirring the two crucibles by a stirrer, synchronously heating the two crucibles by a heater from the outside, wherein the heating temperature of the oil phase substance crucible is 80-90 ℃, and the heating temperature of the water phase substance crucible is 70-85 ℃;
step three: and (5) putting the water phase mixture and the oil phase mixture in the step two into a vacuum emulsifying machine, emulsifying for 30-40 min, and detecting and filling after cooling to room temperature.
Compared with the prior art, the invention has the beneficial effects that: the invention relates to an efficient repairing anti-aging skin care product and a preparation method thereof, wherein double-effect moisturizing factors, tranexamic acid, rose syrup, hexapeptide, grape seed oil, vitronectin and acetylated hexapeptide are used, particularly the hexapeptide and the acetylated hexapeptide are compounds formed by amino acids, so that the product has small molecules, is easy to absorb by skin, has quick anti-aging effect, has the main effects of moisturizing, promoting the generation and secretion of collagen, promoting the metabolism of the skin, lightening melanin, brightening and whitening the skin, has small irritation and wide application range, and can delay skin aging in multiple dimensions.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides an efficient repairing anti-aging skin care product and a preparation method thereof, wherein the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
the first embodiment is as follows: the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
the preparation method of the efficient repairing anti-aging skin care product comprises the following steps:
the method comprises the following steps: firstly, 55 parts of anhydrous ions, 6 parts of glycerol, 1.5 parts of double-effect moisturizing factors, 0.82 part of tranexamic acid, 2 parts of rose syrup, 0.13 part of hexapeptide, 2 parts of grape seed oil, 0.6 part of vitreochrome, 0.11 part of acetylated hexapeptide, 0.1 part of allantoin, 0.08 part of carbomer, 0.16 part of sodium hyaluronate and 0.15 part of triethanolamine are carried out according to the mass parts of the following raw material formula;
step two: respectively placing the oil phase substance and the water phase substance in the step one in two crucibles for dissolving, respectively stirring the two crucibles by a stirrer, synchronously heating the two crucibles by a heater from the outside, wherein the heating temperature of the oil phase substance crucible is 80-90 ℃, and the heating temperature of the water phase substance crucible is 70-85 ℃;
step three: and (3) putting the water phase mixture and the oil phase mixture in the step two into a vacuum emulsifying machine, emulsifying for 30-40 min, and detecting and filling the mixture in the embodiment two after cooling to room temperature: the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
the preparation method of the efficient repairing anti-aging skin care product comprises the following steps:
the method comprises the following steps: firstly, according to the mass parts, 65 parts of anhydrous ions, 8 parts of glycerol, 2.6 parts of double-effect moisturizing factors, 0.84 part of tranexamic acid, 3 parts of rose syrup, 0.15 part of hexapeptide, 6 parts of grape seed oil, 0.7 part of vitriol, 0.12 part of acetylated hexapeptide, 0.2 part of allantoin, 0.1 part of carbomer, 0.18 part of sodium hyaluronate and 0.16 part of triethanolamine are carried out on the following raw material formulas;
step two: respectively placing the oil phase substance and the water phase substance in the step one in two crucibles for dissolving, respectively stirring the two crucibles by a stirrer, synchronously heating the two crucibles by a heater from the outside, wherein the heating temperature of the oil phase substance crucible is 80-90 ℃, and the heating temperature of the water phase substance crucible is 70-85 ℃;
step three: and (3) putting the water phase mixture and the oil phase mixture in the step (II) into a vacuum emulsifying machine for emulsifying, wherein the emulsifying time is 30-40 min, and the detection and filling can be completed after the mixture is cooled to room temperature: the efficient repairing anti-aging skin care product is prepared from the following raw materials in parts by mass:
the preparation method of the efficient repairing anti-aging skin care product comprises the following steps:
the method comprises the following steps: firstly, 75 parts of anhydrous ions, 10 parts of glycerol, 3.2 parts of double-effect moisturizing factors, 0.86 part of tranexamic acid, 4 parts of rose syrup, 0.17 part of hexapeptide, 8 parts of grape seed oil, 0.8 part of vitreochrome, 0.13 part of acetylated hexapeptide, 0.3 part of allantoin, 0.12 part of carbomer, 0.20 part of sodium hyaluronate and 0.17 part of triethanolamine are carried out according to the mass parts of the following raw material formula;
step two: respectively placing the oil-phase substance and the water-phase substance in the first step into two crucibles for dissolving, respectively stirring the two crucibles by a stirrer, synchronously heating the two crucibles by a heater from the outside, wherein the heating temperature of the oil-phase substance crucible is 80-90 ℃, and the heating temperature of the water-phase substance crucible is 70-85 ℃;
step three: and (5) putting the water phase mixture and the oil phase mixture in the step two into a vacuum emulsifying machine, emulsifying for 30-40 min, and detecting and filling after cooling to room temperature.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
5. the efficient repairing anti-aging skin care product and the preparation method thereof according to claim 1 are characterized in that: the preparation method of the efficient repairing anti-aging skin care product comprises the following steps:
the method comprises the following steps: firstly, 55-75 parts of anhydrous ions, 6-10 parts of glycerol, 1.5-3.2 parts of double-effect moisturizing factors, 0.82-0.86 part of tranexamic acid, 2-4 parts of rose syrup, 0.13-0.17 part of hexapeptide, 2-8 parts of grape seed oil, 0.6-0.8 part of vitriol, 0.11-0.13 part of acetylated hexapeptide, 0.1-0.3 part of allantoin, 0.08-0.12 part of carbomer, 0.16-0.20 part of sodium hyaluronate and 0.15-0.17 part of triethanolamine are carried out according to the mass parts of the following raw material formula;
step two: respectively placing the oil phase substance and the water phase substance in the step one in two crucibles for dissolving, respectively stirring the two crucibles by a stirrer, synchronously heating the two crucibles by a heater from the outside, wherein the heating temperature of the oil phase substance crucible is 80-90 ℃, and the heating temperature of the water phase substance crucible is 70-85 ℃;
step three: and (5) putting the water phase mixture and the oil phase mixture in the step two into a vacuum emulsifying machine, emulsifying for 30-40 min, and detecting and filling after cooling to room temperature.
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Application publication date: 20220513 |