CN114469770B - Disposable nursing agent for pets - Google Patents
Disposable nursing agent for pets Download PDFInfo
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- CN114469770B CN114469770B CN202111455144.2A CN202111455144A CN114469770B CN 114469770 B CN114469770 B CN 114469770B CN 202111455144 A CN202111455144 A CN 202111455144A CN 114469770 B CN114469770 B CN 114469770B
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- polyquaternium
- polydimethylsiloxane
- deodorant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a washing-free nursing agent for pets, which comprises an insect repellent, a deodorant and a hair conditioner; the insect repellent is a pesticide
Description
Technical Field
The invention belongs to the technical field of pet nursing, and particularly relates to a washing-free nursing agent for pets.
Background
Nowadays, pets are commonly kept as companion animals by people who are members of the family, and who are in close contact with the pet and even sleep together with the bed. However, most of the pets have dense hair and like to roll over in the grass mud, so that the pets are easy to carry and breed pathogens such as mosquitoes, lice, fleas, mites and the like, and are easy to be infected with various bacteria due to the body taste of the pets. Furthermore, the frequency of pet cleaning is relatively low, typically once a month or even longer. Therefore, in daily care, there is a desire for a pet leave-on care product that performs the functions of sterilization, deodorization, and insect repellent.
However, most of the conventional washing-free care products for pets only have the effects of softening hair or covering smell, and the main components are generally hair conditioning agents or essence, and the effects are single, so that the product cannot meet the expectations of people on multiple effects of degerming, deodorizing, expelling parasites, softening hair and the like. In addition, various corresponding functional raw materials such as a compound insect repellent, a deodorant and a bacteriostatic agent are generally added to realize the effects of expelling insects, removing odor and inhibiting bacteria for the cleaning or nursing products of pets at present. However, compounding various functional raw materials in the product brings great requirements on the compatibility and stability of the product system, and increases the cost of the product. Therefore, the multi-effect integrated pet disposable care product is rarely available in the market at present.
In addition, as the smell of the pet is sensitive, the odor can be removed by adopting a conventional essence masking mode, and the pet is influenced to a certain extent, so that the disposable care product for the pet is more suitable for removing the odor by adopting a chemical method. The existing chemical deodorant comprises zinc ricinoleate and soybean ethyl sulfuric acid ethylmorpholine, wherein the zinc ricinoleate has poor compounding performance with a formula, is not compatible with a cationic surfactant, has an unsaturated structure in the soybean ethyl sulfuric acid ethylmorpholine, and can turn yellow under illumination. Also, pets have the habit of licking their hair, and therefore, the products for pets must be products that achieve a practical non-toxic level.
Disclosure of Invention
The invention aims to provide a washing-free nursing agent for pets, which has good effects of expelling parasites, removing smell, inhibiting bacteria and softening hair, has the property of low irritation, and is safe for pets.
The aim of the invention is achieved by the following technical scheme:
a washing-free caring agent for pets comprises insect repellent, deodorant, and hair conditioner; the insect repellent is a pesticideAn alkane-3, 8-diol;the deodorant has the following structure:
wherein R is 1 Is C14, C16, C18 or C20 alkyl, R 2 Is methyl, ethyl or propyl, R 3 Is methylene, ethylene or propylene.
The invention aims to obtain the pet washing-free nursing agent with effective insect expelling, smell removing, bacteriostasis and low irritation:
firstly, adopting the combination of insect repellent and deodorant to achieve the purposes of expelling insects and removing peculiar smell; wherein, toThe alkane-3, 8-diol (CAS number 42822-86-6) can be used as insect repellent, and can act on lice, flea, mosquito, nasal discharge insect, and Qianchou insect, etc., with long effective time. The deodorant is sulfuric acid ester or phosphoric acid ester with a specific structure, the property of the deodorant is stable, quaternary ammonium salt cationic groups in the structure have positive charges, and nitrogen or sulfur atoms in odor molecules contain lone pair electrons, so that the deodorant can attract odor molecules and combine with the odor molecules to achieve the effect of rapid and stable deodorization; the inventor experiment finds that the deodorant has a certain antibacterial effect.
Meanwhile, through continuous researches of the inventor, the insect repellent and the deodorant are matched and applied to a formula system of the pet washing-free nursing agent, so that the insect repellent and the deodorant have the effects of removing peculiar smell and expelling insects, and can have a synergistic effect, and unexpected antibacterial effect can be achieved when the insect repellent and the deodorant are matched and used, and the peculiar smell and expelling insects of the formula are further improved.
Through the research of the inventor, the reasons why the insect repellent and the deodorant can synergistically improve the deodorizing, insect repellent and antibacterial effects of the pet wash-free care agent are presumed to be as follows: 1. the deodorant is characterized in that the negatively charged sulfate group or phosphate group exists, and is opposite toThe hydroxyl of the alkane-3, 8-diol acts to form a larger molecular structure, and the macromolecular structure has stronger cell membrane penetrating capacity to bacteria and reactivity to odor molecules than any component alone, so that better antibacterial effect and odor removal effect are generated; 2. the deodorant reacts with odor molecules on the surface of the pet, so that the odor of the pet is lightened, and the pet is curedThe alkane-3, 8-diol can more effectively exert the repellent effect of the smell on insects.
Therefore, the pet washing-free nursing agent prepared by compounding the insect repellent, the deodorant and the hair conditioner has good effects of expelling insects, removing smell, inhibiting bacteria and softening hair.
Furthermore, the inventor strictly controls the irritation of the formula from the aspect of the design of the whole formula; the PMD which has the same insect repellent effect as the mosquito repellent amine and is only one sixth of the mosquito repellent amine in toxicity is selected, and is a non-pesticide component, so that the PMD is the only natural active component of the insect repellent allowed to be used in the United states and European Union, and is safe and reliable; the deodorant disclosed by the invention is nontoxic, has the characteristics of stable illumination performance, difficult yellowing, strong compounding capability and the like compared with the existing deodorant, and can be applied to an anionic surfactant system, a cationic surfactant system and a nonionic surfactant system.
The hair conditioner is preferably one or more of polyquaternium, cationic quaternium, water-soluble silicone oil and water-soluble grease.
As a recommended scheme, the additive amount of each component of the pet leave-on nursing agent is 0.5-5% of hair conditioning agent, 0.05-0.2% of insect repellent and 0.1-0.5% of deodorant according to mass percent.
The polyquaternary ammonium salt is one or more of polyquaternary ammonium salt-7, polyquaternary ammonium salt-10, polyquaternary ammonium salt-47, polyquaternary ammonium salt-53 and polyquaternary ammonium salt-39.
The cationic quaternary ammonium salt is one or more of cetyl trimethyl ammonium chloride, lauryl dimethyl ammonium hydroxypropyl hydrolyzed wheat protein, coco dimethyl ammonium hydroxypropyl hydrolyzed silk, dimer oleamide propyl PG-dimethyl ammonium chloride phosphate and distearyl dimethyl ammonium chloride.
The water-soluble silicone oil is one or more of PEG-12 polydimethylsiloxane, PEG/PPG-12/16 polydimethylsiloxane, PEG-14 polydimethylsiloxane, bis-PEG-12 polydimethylsiloxane, PEG-10 polydimethylsiloxane and PEG/PPG-12/18 polydimethylsiloxane.
The water-soluble oil is one or more of water-soluble olive oil, PEG-7 olive oil acid ester, PEG-7 cocoyl glyceride, PEG-6 caprylic/capric glyceride, jojoba wax PEG-120 ester, PEG-75 lanolin, polyglycerol-10 oil acid ester, polyglycerol ether-10 caprylic/capric ester.
Compared with the prior art, the invention has the following beneficial effects:
the pet washing-free nursing agent of the invention is compounded with deodorant and pair with specific structuresThe alkane-3, 8-diol not only can rapidly and stably remove peculiar smell and effectively expel insects, but also can achieve unexpected excellent antibacterial effect without adding any antibacterial agent, and further improves the deodorizing and insect expelling effects of the system; namely, the invention adopts two specific deodorant and insect repellent to achieve the effects of expelling insects, removing smell and inhibiting bacteria.
The no-wash care agent for pets has low irritation, no irritation to eyes, safety to pets and stable formula system.
The pet washing-free nursing agent disclosed by the invention adopts fewer raw materials to obtain good effects of expelling parasites, removing smell, inhibiting bacteria and softening hair, and effectively reduces the product cost.
Detailed Description
The invention is further illustrated by the following specific examples.
The pet leave-in care agents of examples 1 to 10 and comparative examples 1 to 12 were prepared according to the formulations of tables 1 to 4, and the specific preparation method was:
(1) Adding enough water according to the formula, starting stirring, and then adding citric acid and sodium citrate on the basis of the formulas of the examples and the comparative examples to adjust the pH value to 5.0-5.5;
(2) Adding a hair conditioner, stirring and heating, heating to 50-60 ℃, preserving heat, and stirring until the hair conditioner is completely dissolved;
(3) Continuing to keep warm, sequentially adding insect repellent and deodorant, and stirring until the mixture is uniformly mixed;
(4) Cooling to below 45deg.C, and adding appropriate amount of essence; and continuously cooling to normal temperature to obtain the washing-free nursing agent for pets.
The pet leave-in care agents of examples 1 to 6 and comparative examples 1 to 12 were tested for antibacterial effect, deodorizing effect, mosquito repellent effect, and then compared.
For the purpose of illustrating the scheme of the present invention, the 6 kinds of deodorants specifically adopted in the examples and comparative examples have the following structures:
TABLE 1
TABLE 2
TABLE 3 Table 3
TABLE 4 Table 4
The test method of the antibacterial effect, the deodorizing effect and the mosquito repelling effect comprises the following steps:
1. and (3) antibacterial effect test:
the testing method comprises the following steps: the test is carried out according to the 7.3 suspension quantitative method in QB/T2738-2012 evaluation of antibacterial and bacteriostatic effects of daily chemical products, the test concentration of the sample is stock solution, and the action time is 10 minutes.
2. And (3) deodorizing effect test:
the testing method comprises the following steps: the deodorizing performance of the soaked fabric is tested by taking ammonia gas as odor, the fabric material is selected from rabbit hair or wool, the soaking method is to soak the fabric material in the stock solution for 10 minutes, the fabric material is not soaked in water and is dried at room temperature, and the soaking solution adopts the formula shown in the embodiment. The fabric was cut into a round shape with a diameter of 4cm, 0.1mL of ammonia water was sucked up on a glass dish, the glass dish was placed at the bottom of the dryer, the fabric was placed on a tray of the dryer, ammonia was sucked up for 14 hours, and after the ammonia suction was completed, 100.0mL of distilled water was used for extraction at 40℃for 2 hours. The ammonia content in the extract is measured by adopting HJ 534-2009 'determination of environmental air ammonia sodium hypochlorite-salicylic acid spectrophotometry', and the deodorizing rate of the soaked fabric is indirectly obtained by dividing the difference value of the total ammonia amount and the difference value of the adsorption ammonia of the soaked fabric by the difference value of the adsorption ammonia of the non-soaked fabric.
Deodorization ratio = (ammonia adsorbed on fabric after soaking-ammonia adsorbed by non-soaked fabric)/(total ammonia amount-ammonia adsorbed by non-soaked fabric) ×100%
3. Mosquito repelling rate test
Reference standard GB/T13917.9-2009 "pesticide registration hygienic pesticide indoor efficacy test and evaluation part 9: repellent(s);
test insects: aedes albopictus (Aedes albopictus), female adults that did not take blood 4-7 days after eclosion;
test conditions: the temperature is 25+/-2 ℃ and the relative humidity is 60-70%;
the test method comprises the following steps: selecting 4 qualified testers, and coiling skin area of 50mm×50mm on each face of the back of each hand, wherein the application amount of stock solution of one hand sample is 1.5 μL/cm 2 Is applied to expose 40mm x 40mm skin, closely cover the rest, and the other hand is blank. And immediately after the application, carrying out a repellent rate test. Each tester firstly puts the control hand into the mosquito cage, immediately counts time, records the stopping number of mosquitoes and tests for 5 minutes. Then the tester puts the hand smeared with the sample into a mosquito cage, tests the hand and records the stopping number of the mosquitoes in the same way. The repellency was calculated from the repeated test data as follows:
P＝(N-K)/N×100％
wherein P is the repellent rate,%; n is the total stopping number of the control hand mosquitoes, and the unit is 'only'; k is the total number of hand and mosquito stopping after sample washing, and the unit is "only".
It should be noted that the above-mentioned embodiments are merely for further explanation of the present invention and are not intended to limit the present invention, and any modifications or variations within the meaning and scope of the technical solutions of the present invention, which are considered to be included in the scope of the present invention by those skilled in the art.
Claims (6)
1. The pet washing-free nursing agent is characterized by comprising 0.05-0.2% of insect repellent, 0.1-0.5% of deodorant and 0.5-5% of hair conditioner by mass percent; the insect repellent is a pesticideAn alkane-3, 8-diol; the deodorant has the following structure:
wherein R is 1 Is C14, C16, C18 or C20 alkyl, R 2 Is methyl, ethyl or propyl, R 3 Is methylene, ethylene or propylene.
2. The leave-in pet care formulation of claim 1, wherein the hair conditioning agent is one or more of a polyquaternium, a cationic quaternium, a water soluble silicone oil, and a water soluble grease.
3. The leave-in pet care agent according to claim 2, wherein the polyquaternium is one or more of polyquaternium-7, polyquaternium-10, polyquaternium-47, polyquaternium-53, and polyquaternium-39.
4. The leave-in pet care formulation of claim 2, wherein the cationic quaternary ammonium salt is one or more of cetyl trimethylammonium chloride, lauryl dimethylammonium hydroxypropyl hydrolyzed wheat protein, coco dimethylammonium hydroxypropyl hydrolyzed silk, dimer oleamide propyl PG-dimethylammonium phosphate, distearyl dimethylammonium chloride.
5. The leave-in pet care formulation of claim 2, wherein the water-soluble silicone oil is one or more of PEG-12 polydimethylsiloxane, PEG/PPG-12/16 polydimethylsiloxane, PEG-14 polydimethylsiloxane, bis-PEG-12 polydimethylsiloxane, PEG-10 polydimethylsiloxane, PEG/PPG-12/18 polydimethylsiloxane.
6. The leave-in pet care formulation of claim 2, wherein the water-soluble oil is one or more of water-soluble olive oil, PEG-7 olive oleate, PEG-7 cocoyl glyceride, PEG-6 caprylic/capric glyceride, jojoba wax PEG-120 ester, PEG-75 lanolin, polyglycerol-10 oleate, polyglycerol ether-10 caprylic/capric ester.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111455144.2A CN114469770B (en) | 2021-11-30 | 2021-11-30 | Disposable nursing agent for pets |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111455144.2A CN114469770B (en) | 2021-11-30 | 2021-11-30 | Disposable nursing agent for pets |
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| CN114469770A CN114469770A (en) | 2022-05-13 |
| CN114469770B true CN114469770B (en) | 2023-08-29 |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115645303B (en) * | 2022-11-16 | 2023-04-07 | 南京天纵易康生物科技股份有限公司 | Water-in-oil composition with high water phase content and containing saccharides or acids, salts thereof or amino acids, and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10146349A (en) * | 1996-11-15 | 1998-06-02 | Nippon Doubutsu Yakuhin Kk | Deodorant for animal |
| CN105726423A (en) * | 2016-05-11 | 2016-07-06 | 于文 | Multifunctional concentrated cleaner for pets and preparation method thereof |
| CN106619309A (en) * | 2017-01-09 | 2017-05-10 | 杭州科润生物科技有限公司 | Pet nursing agent and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2626230T3 (en) * | 2008-11-20 | 2017-07-24 | The Procter & Gamble Company | Compositions for personal hygiene that provide an improved cooling sensation |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10146349A (en) * | 1996-11-15 | 1998-06-02 | Nippon Doubutsu Yakuhin Kk | Deodorant for animal |
| CN105726423A (en) * | 2016-05-11 | 2016-07-06 | 于文 | Multifunctional concentrated cleaner for pets and preparation method thereof |
| CN106619309A (en) * | 2017-01-09 | 2017-05-10 | 杭州科润生物科技有限公司 | Pet nursing agent and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| Repellent Activities of Stereoisomers of p-Menthane-3,8-diols Against Anopheles gambiae (Diptera: Culicidae);STEPHEN S. BARASA等;《J. Med. Entomol》;第39卷(第5期);736-741 * |
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