CN114469769A - Bath oil for infants and children and preparation method thereof - Google Patents

Bath oil for infants and children and preparation method thereof Download PDF

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CN114469769A
CN114469769A CN202210280149.4A CN202210280149A CN114469769A CN 114469769 A CN114469769 A CN 114469769A CN 202210280149 A CN202210280149 A CN 202210280149A CN 114469769 A CN114469769 A CN 114469769A
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infants
bath oil
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史学东
吴明城
吴秋荣
欧海浩
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Guangzhou Deva Biological Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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Abstract

The invention discloses bath oil for infants and children and a preparation method thereof, and belongs to the technical field of daily chemicals. The bath oil for infants and children comprises active effective components consisting of arginine, glycolipid and jojoba seed oil; the active functional components account for 3.5-12% of the bath oil by mass. The bath oil disclosed by the invention is stable and lasting in foam, high in safety, mild and non-irritating to skin, and capable of removing redness and inhibiting skin inflammatory reaction; according to the invention, through screening the types and contents of the components, the bath oil has fresh, moist and non-fake skin feeling; the bath oil disclosed by the invention has better moisturizing and skin inflammation inhibiting effects through the synergistic effect of arginine, glycolipid and jojoba seed oil.

Description

Bath oil for infants and children and preparation method thereof
Technical Field
The invention relates to bath oil for infants and children and a preparation method thereof, and belongs to the technical field of daily chemicals.
Background
Research shows that the average thickness of the horny layer of the infant is 5.3 +/-1.4 microns, which is about 1-3 microns thinner than that of an adult, and meanwhile, the skin of the infant and children in east Asia is more easily affected by factors such as air pollution, extreme weather and the like because the horny layer is thinner. The skin care difficulty of Chinese infants is that the skin cuticle of the infants is thinner, the water locking capacity is weaker, and the infants are more easily stimulated by the external environment, so that the skin problems of eczema, saliva rash, apple faces and the like are caused. The ratio of skin area to body weight of infants and children is much larger than that of adults; the skin of the infants is thin (the epidermis of the adults is about 5-15 layers, the epidermis of the infants is only a single layer, and the collagen fiber in the dermis is few and lacks elasticity), so the infants are easy to damage due to friction; the skin of infants has poor acid and alkali control capability; the skin pigment layer is thin; the sweat glands and blood vessels are not completely developed, the skin temperature regulating capability is weak, and miliaria can be easily caused; the immune system is not developed completely, the skin resistance is poor, and allergy is easy to occur; the lacrimal gland is incompletely developed, the winks are few, and the eyes are easily stimulated; the skin of the baby is thin and tender, rich in blood vessels, strong in absorption and permeability and strong in osmosis.
Patent application number CN2019113329274 discloses a bubble bath oil and a preparation method thereof, which comprises the following components in percentage by weight: sweet almond oil: 30-55%, cocamide DEA: 1-4%, laureth sulfate TIPA salt: 15-25%, propylene glycol: 3-8%, laureth-4: 20-35%, PEG-7 glyceryl cocoate: 1-4% and auxiliary components: 0.5 to 1 percent, and 15 to 25 percent of laureth sulfate TIPA salt contained in the formula of the invention has higher addition amount, which can bring stimulation to the skin of babies. Patent application No. CN2020108700322 discloses bath oil with foamability and moisturizing property and a preparation method thereof, wherein the bath oil comprises the following raw materials in parts by weight: 25-35 parts of ethylhexyl palmitate, 22-25 parts of propylene glycol, 19-23 parts of sodium laureth sulfate, 7-11 parts of water, 305-7 parts of laureth, 3-5 parts of white chinlon oil, 0.4-0.6 part of tocopherol nicotinate, 2-4 parts of cocamide, 0.8-1.2 parts of sodium lauroyl oat amino acid, 0.8-1.2 parts of PEG-6 caprylic/capric glyceride, 0.8-1.2 parts of sodium cocoyl malate and 0.08-0.12 part of essence, wherein the formula contains the sodium laureth sulfate with a higher addition amount of 19-23 parts, is relatively irritant to the skin of infants and is not suitable for the infants. At present, no bath oil specially aiming at the skin of infants and children is available in the market.
Disclosure of Invention
The invention aims to provide bath oil for infants and children and a preparation method thereof.
In order to achieve the purpose, the invention adopts the technical scheme that:
a bath oil for infants and children comprises active functional components consisting of arginine, glycolipid and jojoba seed oil; the active functional components account for 3.5-12% of the bath oil by mass.
The research shows that the arginine belongs to basic amino acid and has the effects of keeping skin moisture, smoothing skin and reducing the peeling of scurf. Glycolipid is a latest generation humectant developed in recent years, is a water-soluble lipid substance, has a structure similar to that of a substance constituting the horny layer of the skin, can quickly permeate into the skin, and is combined with water in the horny layer to form a network structure to lock water. Jojoba seed oil is also called jojoba oil and jojoba oil, and is grease which is obtained by further processing and refining jojoba seeds after being squeezed, the jojoba seed oil has good compatibility with skin, is easy to be absorbed by the skin, has a skin moistening effect, is not greasy, and has strong oxidation resistance; the jojoba seed oil is similar to grease secreted by human bodies, can be well mixed with sebum, forms a layer of breathable film on the surface layer of skin, cannot block skin respiration and moisture permeation, can prevent moisture evaporation, and cannot block pores, so that the jojoba seed oil cannot be braised and cause acne; the jojoba seed oil can also dissolve dirt and aged keratinocytes, and the jojoba seed oil can keep skin moist and fine. Through a large number of experiments, the inventor discovers that the combination of arginine, glycolipid and jojoba seed oil has good synergistic effect in the aspects of moisturizing and inhibiting skin inflammation.
As a preferable embodiment of the bath oil for babies, the active functional ingredient accounts for 6-8.5% of the mass of the bath oil. At this content, arginine, glycolipid and jojoba oil exert better moisturizing and skin inflammation inhibiting effects.
As a preferred embodiment of the bath oil for infants and children, the mass ratio of arginine, glycolipid and jojoba seed oil in the active functional ingredients is arginine: glycolipid: jojoba seed oil (2-3), (2.5-3), (1.5-2.5). Through a large number of experiments, the inventor finds that under the condition, the arginine, the glycolipid and the jojoba seed oil have stronger synergistic effect and better moisturizing and skin inflammation inhibiting effects.
As a preferred embodiment of the bath oil for infants and children, the glycolipid is a biological glycolipid. The glycolipid is selected from biological glycolipid Bio-201, is prepared by fermenting natural plants, is 100 percent biodegradable based on renewable raw materials, can reduce the damage of waste water to natural water and water ecology in the washing process, is safe and non-toxic, has high-efficiency and excellent cleaning function and solubilization property, can reduce the irritation of other surfactants to skin, and has the effects of sterilizing, removing red, inhibiting skin inflammatory reaction and regulating immunity.
As a preferred embodiment of the bath oil for babies according to the present invention, the bath oil further comprises a fat, a surfactant and an emulsifier; the grease comprises caprylic capric triglyceride and PEG-7 glyceryl cocoate; the surfactants include cocamide methyl MEA and lauryl hydroxy sulfobetaine; the emulsifier comprises laureth-6 carboxylic acid and polyglycerol-10 laurate.
In a preferred embodiment of the bath oil for babies, the bath oil comprises, by mass, 35-55% of caprylic/capric triglyceride, 0.1-0.8% of PEG-7 glyceryl cocoate, 30-35% of cocamide methyl MEA, 0.4-2% of lauryl hydroxy sulfobetaine, 5-8% of laureth-6 carboxylic acid and 1-4% of polyglycerol-10 laurate. The caprylic capric triglyceride is high-definition odorless oil, is a derivative of palm oil or coconut oil, can be compatible with human skin, and has non-greasy texture. Cocamide methyl MEA is a white waxy substance with foaming cleansing ability and excellent moisturizing and conditioning ability. Lauryl hydroxy sulfobetaine is a zwitterionic surfactant, has excellent stability under both acidic and alkaline conditions, and has the characteristics of more foams and strong detergency. The polyglycerol-10 laurate has the functions of emulsification, dispersion, stabilization, conditioning and viscosity control, is green and safe, has no stimulation to skin, and has good water solubility. The inventor screens the types and the contents of all components in the bath oil for the infants and the children, so that the bath oil for the infants and the children is fresh and clean and is not pseudo-smooth, and the greasy skin feeling brought by a full-oil system is improved.
In a preferred embodiment of the bath oil for babies, the bath oil comprises, by mass, 40-50% of caprylic/capric triglyceride, 0.2-0.5% of PEG-7 glyceryl cocoate, 31-34% of cocamide methyl MEA, 0.5-1.5% of lauryl hydroxy sulfobetaine, 6-7% of laureth-6 carboxylic acid and 2-3% of polyglycerol-10 laurate. Under the condition, the bath oil for infants and children not only has fresh skin feel, but also has better mildness and moisture retention.
As a preferred embodiment of the bath oil for babies and children of the present invention, the bath oil for babies and children further comprises a solvent; the solvent is water. The bath oil of the invention adopts water as a solvent, so that the bath oil is more mild and non-irritant.
In a preferred embodiment of the bath oil for infants and children, the water accounts for 2-6% of the mass of the bath oil.
The invention also provides a preparation method of the bath oil for infants and children, which comprises the following steps:
(1) uniformly mixing laureth-6-carboxylic acid, cocamide methyl MEA, water and arginine, homogenizing at the conditions of 30-40 rpm, 75-80 ℃ and-0.05-0.04 MPa, keeping the temperature unchanged, and homogenizing until the material body is transparent to obtain a feed liquid A;
(2) adding polyglycerol-10 laurate into the feed liquid A, cooling, adding glycolipid, lauryl hydroxy sulfobetaine and PEG-7 glycerol cocoate, and stirring to obtain feed liquid B;
(3) and adding caprylic/capric triglyceride and jojoba seed oil into the material liquid B, uniformly stirring, cooling, discharging and standing to obtain the bath oil for infants.
Compared with the prior art, the invention has the beneficial effects that: the bath oil for infants and children provided by the invention has the advantages of stable and lasting foam, high safety, mildness, no skin irritation, capability of removing redness and inhibiting skin inflammatory reaction; according to the invention, through screening the types and contents of the components, the bath oil has fresh, moist and non-fake skin feeling; the bath oil disclosed by the invention has better moisturizing and skin inflammation inhibiting effects through the synergistic effect of arginine, glycolipid and jojoba seed oil.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Examples 1 to 7
A bath oil for infants and children comprises components and contents shown in Table 1.
TABLE 1 weight percent/% of each component in the bath oils for infants and children of examples 1 to 7
Figure BDA0003557539440000041
Figure BDA0003557539440000051
The preparation method of the bath oil for infants and children in embodiments 1 to 7 comprises the following steps:
(1) uniformly mixing laureth-6-carboxylic acid, cocamide methyl MEA, water and arginine, homogenizing at 35rpm, 78 deg.C and-0.05 MPa for 3min, keeping temperature unchanged, homogenizing every 5min for 2min until the material body is in a casting state, and obtaining feed liquid A;
(2) adding polyglycerol 10 laurate into the feed liquid A, cooling to 45 ℃, adding glycolipid, lauryl hydroxy sulfobetaine and PEG-7 glyceryl cocoate, and stirring for 5min to obtain feed liquid B;
(3) adding caprylic/capric triglyceride and jojoba seed oil into the material liquid B, stirring for 5min, cooling to below 40 deg.C, discharging, and standing to obtain the bath oil for infants.
Comparative examples 1 to 9
A bath oil for infants and children comprises components and contents shown in Table 2.
TABLE 2 weight percent/% of each component in the bath oil for infants and children of comparative examples 1 to 9
Figure BDA0003557539440000061
The preparation method of the bath oil for infants and children in the comparative examples 1 to 9 is the same as that of the example 1.
Examples of effects
1. Evaluation of safety
Product safety evaluation: the tested population is children, 70 people and the age is between 1 and 12 years. The skin of the subject is healthy, has no allergic history of the skin disease, and meets the voluntary entry standard of the subject. Randomly grouped into 7 groups of 10 people each.
The test method is a human body patch test. Selecting a qualified spot tester, placing 0.020-0.025g of a tested object in the spot tester, sticking the spot tester with the tested object on the back or the bent side of the forearm of the tested object by using a non-irritating adhesive tape, and lightly pressing with a palm to uniformly stick the spot tester on the skin for 24 hours. And (5) removing the tested spot tester for 30min, and observing skin reaction after the indentation disappears. If the result is negative, the test is observed once more at 24h and 48h after the patch test. The results were recorded according to the reference standards of "standards for hygiene of cosmetics" in 2007 and "standards for safety of cosmetics" in 2015.
Evaluation criteria: level 0: negative reaction; level 1: suspicious reactions, only weak erythema; and 2, stage: weak positive reaction, erythema, infiltration, edema, and possibly pimple; and 3, level: strong positive reaction, erythema, infiltration, edema, pimple and reaction beyond the tested area; 4, level: very strong positive reaction, obvious erythema, severe infiltration, edema, herpes fusiformis and reaction beyond the tested area.
The patch test result of the human skin shows that: the skin reactions of the subjects were observed 24h and 48h after the test by the spot-sticking test of the bath oil for infants and children of examples 1 to 7, and all the subjects had negative skin reactions, which indicates that the bath oil for infants and children prepared by the invention is safe to use.
2. Test of moisturizing Effect
(1) The test method comprises the following steps: 160 children aged 1-12 are selected as trial objects and divided into 16 groups of 10 persons, and one sample of examples 1-7 and comparative examples 1-9 is tried on each group. Each group of test persons respectively tried the bath oil for infants and children in examples 1-7 and comparative examples 1-9 to bath, then the moisture content of the left forearm is measured in a constant temperature and humidity environment (the temperature is 25 ℃, the humidity is 60%), and the skin moisture content 1 hour and 2 hours after bath is respectively measured by a moisture meter and is respectively recorded as H1、H2
(2) The test results are shown in table 3.
TABLE 3
Figure BDA0003557539440000071
Figure BDA0003557539440000081
As can be seen from table 3, as the content of the active functional ingredient in the bath oil increases, the moisturizing effect of the bath oil also increases, but when the content of the active functional ingredient exceeds 7.1%, the moisturizing effect is not remarkably improved, and the moisturizing effect tends to be saturated; compared with comparative examples 5 to 7, the bath oil of examples 1 to 7 has better moisturizing effect, which shows that arginine, glycolipid and jojoba seed oil in the active functional components have better moisturizing effect through synergistic effect.
3. Appearance and stability testing
The appearance, smell and stability of the bath oils for infants and children of examples 1 to 7 and comparative examples 1 to 9 were evaluated according to GB/T34857-2017 and GB/T29680-2013, and the results are shown in Table 4. Wherein the heat resistance is as follows: keeping the bath oil at 38-45 ℃ for 24 hours, and observing the appearance change of the bath oil after the bath oil is recovered to room temperature; the cold resistance is as follows: and (3) keeping the bath oil at the temperature of-7-3 ℃ for 24 hours, and observing the appearance change of the bath oil after the bath oil is recovered to the room temperature.
TABLE 4
Figure BDA0003557539440000091
Figure BDA0003557539440000101
As is clear from Table 4, the bath oils of examples 1 to 7 are excellent in appearance, odor, heat resistance and cold resistance.
4. Skin feel verification test
The test method comprises the following steps: selecting 30 children aged 1-12 years as trial objects, and respectively trying the samples of examples 1-7 and comparative examples 1-9. The test subjects respectively tried the bath oil for babies and children of examples 1 to 7 and comparative examples 1 to 9 to perform bath, and the effect evaluation was performed on the cleanliness of washing, whether the babies and children had a pseudo-slip state, and the skin feeling after washing, and the test results are shown in table 5. A in Table 5, the degree of rinsing is easy to rinse; b is not easy to wash clean; whether the false slipping is caused or not in the table 5 is that the false slipping is not caused after washing; b, false slipping after washing; in Table 5, A for the skin feel after washing is water-wet after washing; b is neither water nor dry after washing; and C, washing and drying.
TABLE 5
Figure BDA0003557539440000111
As can be seen from table 5, compared to comparative examples 1 to 2, the evaluation of the skin feel after washing of the bath oil of example 1 was higher, which indicates that the content of the active functional ingredient has a great influence on the skin feel after washing of the bath oil, and the higher the content of the active functional ingredient is, the better the content is not; compared with comparative examples 5-7, the skin feel of the bath oil in examples 1-7 after washing is better, and the arginine, the glycolipid and the jojoba seed oil in the active functional components have better moisturizing and moistening effects through the synergistic effect.
5. Test for efficacy in reducing skin redness and inflammatory response
The test method comprises the following steps: 160 children of 1-12 years old with obvious red miliaria on skin are selected as trial objects and divided into 14 groups, 10 persons in each group are selected, and one sample of examples 1-7 and comparative examples 1-9 is tried on each group. Each group of test persons respectively try out the bath oil for the infants and children in the examples 1-7 and the comparative examples 1-9 to bath for one week continuously and once a day. And (3) a one-week later scoring mode (0-10 points, the higher the score is, the better the representative effect is), and the final score of each sample is the average value of the scores of the corresponding group of subjects. The scoring results are shown in table 6.
TABLE 6
Figure BDA0003557539440000121
Figure BDA0003557539440000131
As can be seen from Table 6, the bath oils of examples 1 to 7 had excellent effects of reducing skin redness and inflammatory reaction, of which example 3 had the best effect; compared with comparative examples 5-7, the bath oil in example 3 has better effects on removing skin redness, eliminating miliaria, inhibiting skin itching and stinging and the like, and shows that arginine, glycolipid and jojoba seed oil in active functional components have better moisturizing and moistening effects through synergistic effect.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (10)

1. A bath oil for infants and children, which is characterized in that the bath oil comprises active functional components consisting of arginine, glycolipid and jojoba seed oil; the active functional components account for 3.5-12% of the bath oil by mass.
2. The bath oil for infants and children as claimed in claim 1, wherein the active functional ingredients account for 6-8.5% of the mass of the bath oil.
3. The body wash oil for infants and children according to claim 1, wherein the mass ratio of arginine, glycolipid and jojoba seed oil in the active effective components is arginine: glycolipid: jojoba seed oil (2-3), (2.5-3), (1.5-2.5).
4. A body wash oil for infants and young children according to claim 1, wherein said glycolipid is a biological glycolipid.
5. The body wash oil for infants and young children according to claim 1, further comprising a fat, a surfactant and an emulsifier; the grease comprises caprylic capric triglyceride and PEG-7 glyceryl cocoate; the surfactants include cocamide methyl MEA and lauryl hydroxy sulfobetaine; the emulsifier comprises laureth-6 carboxylic acid and polyglycerol-10 laurate.
6. The bath oil for babies as claimed in claim 5, wherein the bath oil comprises, by mass, 35-55% of caprylic/capric triglyceride, 0.1-0.8% of PEG-7 glyceryl cocoate, 30-35% of cocamide methyl MEA, 0.4-2% of lauryl hydroxy sulfobetaine, 5-8% of laureth-6 carboxylic acid and 1-4% of polyglycerol-10 laurate.
7. The bath oil for infants according to claim 6, wherein the bath oil comprises, by mass, 40-50% of caprylic capric triglyceride, 0.2-0.5% of PEG-7 glyceryl cocoate, 31-34% of cocamide methyl MEA, 0.5-1.5% of lauryl hydroxy sulfobetaine, 6-7% of laureth-6 carboxylic acid and 2-3% of polyglycerol-10 laurate.
8. The body wash oil for infants and children according to claim 1, further comprising a solvent; the solvent is water.
9. The body wash oil for infants and children according to claim 8, wherein the water accounts for 2-6% of the mass of the body wash oil.
10. A method of preparing a body wash oil for infants and children as claimed in any one of claims 1 to 9, comprising the steps of:
(1) uniformly mixing laureth-6-carboxylic acid, cocamide methyl MEA, water and arginine, homogenizing at the conditions of 30-40 rpm, 75-80 ℃ and-0.05-0.04 MPa, keeping the temperature unchanged, and homogenizing until the material body is transparent to obtain a feed liquid A;
(2) adding polyglycerol-10 laurate into the feed liquid A, cooling, adding glycolipid, lauryl hydroxy sulfobetaine and PEG-7 glycerol cocoate, and stirring to obtain feed liquid B;
(3) and adding caprylic/capric triglyceride and jojoba seed oil into the material liquid B, uniformly stirring, cooling, discharging and standing to obtain the bath oil for infants.
CN202210280149.4A 2022-03-22 2022-03-22 Bath oil for infants and children and preparation method thereof Pending CN114469769A (en)

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CN114983843A (en) * 2022-05-27 2022-09-02 广州天玺生物科技有限公司 Infant amino acid cleansing bubble with desensitizing and skin care effects
CN115737499A (en) * 2022-11-18 2023-03-07 杭州心悦化妆品有限公司 Self-heating type moistening and moisturizing bath oil and preparation method thereof
CN116421504A (en) * 2023-05-08 2023-07-14 珠海博御中医药研究有限公司 Bath oil with high foam and high moisture content and dermatitis relieving function and preparation method thereof

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CN110090182A (en) * 2019-04-18 2019-08-06 保利沃利科技(武汉)有限公司 A kind of mild bath oil and preparation method thereof
CN111437219A (en) * 2019-10-31 2020-07-24 上海新如生物科技有限公司 Weakly acidic body wash and preparation method thereof
CN111529429A (en) * 2020-06-16 2020-08-14 上海江笙生物科技有限公司 Bath oil and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114983843A (en) * 2022-05-27 2022-09-02 广州天玺生物科技有限公司 Infant amino acid cleansing bubble with desensitizing and skin care effects
CN115737499A (en) * 2022-11-18 2023-03-07 杭州心悦化妆品有限公司 Self-heating type moistening and moisturizing bath oil and preparation method thereof
CN116421504A (en) * 2023-05-08 2023-07-14 珠海博御中医药研究有限公司 Bath oil with high foam and high moisture content and dermatitis relieving function and preparation method thereof

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Application publication date: 20220513