CN1144694A - External-applied interferon medicine - Google Patents
External-applied interferon medicine Download PDFInfo
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- CN1144694A CN1144694A CN 95113741 CN95113741A CN1144694A CN 1144694 A CN1144694 A CN 1144694A CN 95113741 CN95113741 CN 95113741 CN 95113741 A CN95113741 A CN 95113741A CN 1144694 A CN1144694 A CN 1144694A
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- interferon
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Abstract
A kind of exterior-use interferon medicines of treating mucosa diseases and dermatosis related to virus, especially the cervical erosion with special curative effect include capsule prepared from interferon with 0.5-10 millions units of activity or the mixture of interferon and extract of Chinese medicinal materials, medicinal film prepared from interferon and antibiotic, and cream, tablet, or suppository prepared from interferon and other medicines.
Description
The present invention relates to a kind of medicine for external use made from interferon.
Interferon is the important cytokines of a class, and they have various biological activity such as broad-spectrum antiviral, anti-cell division, immunomodulating on allogenic cell, studies show that through 20 clinical application for many years it is a kind of important antiviral, antineoplaston medicine.Have more than 40 country to use interferon formulation at present, treat about more than 30 kinds of diseases, the disease kind of treatment is mainly cancer and disease of viral infection.Chinese scholar utilizes genetic engineering interferon that mucosa and the dermatosiss relevant with virus such as cervical erosion, verruca vulgaris, young flat wart, condyloma acuminatum, herpes have been carried out vast amount of clinical work, all obtained good and clinical curative effect, Therapeutic Method is that the method for tiing up is pasted in intramuscular injection, local injection, gauze, use inconvenience but these methods all exist, the not high and cost of focus local drug concentration is crossed high shortcoming.
The objective of the invention is interferon is made medicine for external use, topical treatment some with relevant mucosal disease, the dermatosiss of virus, aim to provide a kind of local topical medicine of easy to use, economical, raising curative effect.
Purpose of the present invention can reach by following measure: the interferon capsule, with activity is that the interferon of 50-1000 ten thousand active units mixes the back dress and makes capsule with Chinese herbal medicine extract, wherein Chinese herbal medicine can be to have heat-clearing and toxic substances removing, damp eliminating, parasite killing, remove the Chinese medicine of wind itching-relieving efficacies, as Cortex Dictamni: 12.5-13.8%, Borneolum Syntheticum: 3.1-4.2%, Radix Sophorae Flavescentis: 12.5-13.8%, Cortex Phellodendri: 9.2-16.7%, Fructus Cnidii: 9.2-16.7%, continuous careless moss: 20.7-27.8%, Herba Andrographis: 12.5-18.5%, Indigo Naturalis: 4.2-4.6%, said medicine is removed Borneolum Syntheticum, Indigo Naturalis grinds to form outside the fine powder together, all the other Chinese medicines water decoction secondary are together made extract powder, cold drying, the Borneolum Syntheticum of time spent and fine-powdered, Indigo Naturalis is mixed the back dress together and is made capsule with interferon.In addition, the antibiotics of also can in capsule, packing into, wherein antibiotics can be metronidazole, gentamycin, chloromycetin, nitrofural, boric acid etc.
Purpose of the present invention can also reach by following measure: interferon medicine film, with activity be the interferon of 50-1000 ten thousand active units with antibiotics, be mixed together pusher at film forming holder (as polyvinyl alcohol) and make film, make interferon medicine film.
Purpose of the present invention can also reach by following measure: as required interferon is made the medicine for external use of other dosage form with other medicines, as cream, tablet, suppository etc.
Advantage of the present invention is:
Treat some limitation diseases of viral infection with interferon local application, can make the diseased region interferon keep high level, virus infected cell can directly be subjected to the effect of high concentration interferon, and not only economy but also reduce toxic reaction and improve curative effect was easy to use.Can be used for treating mucosa and skin viral infection diseases such as cervical erosion, also can become the control good medicine of some gynecologic malignant tumor and certain property sexually transmitted disease (STD).
Below in conjunction with embodiment in detail the present invention is described in detail:
1. interferon capsule: Cortex Dictamni 9g, Borneolum Syntheticum 3g, Radix Sophorae Flavescentis 9g, Cortex Phellodendri 12g, Fructus Cnidii 12g, continuous careless moss 15g, Herba Andrographis 9g, Indigo Naturalis 3g grind to form fine powder with Borneolum Syntheticum with Indigo Naturalis; Other medicines boil secondary with decocting, make extract powder, and cold drying mixes with 3,000,000 active unit's interferon with the Borneolum Syntheticum that is ground into fine powder, Indigo Naturalis that the back is aseptic to be incapsulated again.
2. interferon medicine film adds 10 gram metronidazoles, interferon 3 * 10 after being cooled to room temperature with 22.5 gram polyvinyl alcohol dissolving sterilizations
8Active unit, mixing is the pushing film forming in sterilizing room, and airing cuts into 100 medicine films sterilized packing bag of packing into after 24 hours.
Claims (4)
1. external-applied interferon medicine, it is characterized in that with activity being that the interferon of 50-1000 ten thousand active units mixes the back dress and makes capsule with Chinese herbal medicine extract, wherein Chinese herbal medicine can be to have heat-clearing and toxic substances removing, damp eliminating, parasite killing, remove the Chinese medicine of wind itching-relieving efficacies, as Cortex Dictamni: 12.5-13.8%, Borneolum Syntheticum: 3.1-4.2%, Radix Sophorae Flavescentis: 12.5-13.8%, Cortex Phellodendri: 9.2-16.7%, Fructus Cnidii: 9.2-16.7%, continuous careless moss: 20.7-27.8%, Herba Andrographis: 12.5-18.5%, Indigo Naturalis: 4.2-4.6%, said medicine is removed Borneolum Syntheticum, Indigo Naturalis grinds to form outside the fine powder together, all the other Chinese medicines water together decoct secondary, make extract powder, mix, cold drying, the Borneolum Syntheticum of time spent and fine-powdered, Indigo Naturalis is mixed the back dress together and is made capsule with interferon.
2. external-applied interferon medicine according to claim 1, when its dosage form is capsule, the antibiotics of also can in capsule, packing into, wherein antibiotics can be metronidazole, gentamycin, chloromycetin, nitrofural, boric acid etc.
3. external-applied interferon medicine according to claim 1, it is characterized in that with activity be the interferon of 50-1000 ten thousand active units with antibiotics, be mixed together pusher at film forming holder (as polyvinyl alcohol) and make film, make interferon medicine film.
4. external-applied interferon medicine according to claim 1 and 2, it is characterized in that can be as required with interferon with other medicines make the medicine for external use of other dosage form, as cream, tablet, suppository etc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95113741 CN1144694A (en) | 1995-09-07 | 1995-09-07 | External-applied interferon medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95113741 CN1144694A (en) | 1995-09-07 | 1995-09-07 | External-applied interferon medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1144694A true CN1144694A (en) | 1997-03-12 |
Family
ID=5080061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 95113741 Pending CN1144694A (en) | 1995-09-07 | 1995-09-07 | External-applied interferon medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1144694A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113521156A (en) * | 2021-08-24 | 2021-10-22 | 苏州龙达生物科技有限公司 | Traditional Chinese medicine composition for resisting HPV infection and preparation method thereof |
-
1995
- 1995-09-07 CN CN 95113741 patent/CN1144694A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113521156A (en) * | 2021-08-24 | 2021-10-22 | 苏州龙达生物科技有限公司 | Traditional Chinese medicine composition for resisting HPV infection and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |