CN1047090C - Plaster for curing cough with dyspnea - Google Patents

Abstract

The present invention relates to a pure traditional Chinese medicine of a patch for curing coughs with dyspnea. The patch of the present invention can be prepared by selecting prescription components from the following traditional Chinese medicines: 10 to 15 portions of heartleaf houttuynia herb, 5 to 12 portions of Ephedra herb, 5 to 15 portions of tansymustard seed, 5 to 12 portions of cape jasmine fruit, 5 to 10 portions of Pinellia tuber, 5 to 10 portions of tangerine peel, 5 to 12 portions of bitter apricot seed, 5 to 10 portions of liquorice, 5 to 15 portions of perilla fruit, 5 to 12 portions of baical skullcap root, 5 to 10 portions of platycodon root, 5 to 13 portions of zedoary, 10 to 15 portions of red sage root and 5 to 10 portions of rhubarb. The dosage forms of the patch can be adhesive plasters or powder adhered to adhesive plasters used as carriers. When used, the patch is adhered to the shanzhong acupoint for curing trachitis and pneumonia. The present invention has the advantages of internal disease treatment from external, convenience and security.

Description

The Chinese herbs paste of treatment tracheitis, pneumonia

The present invention relates to a kind of new pharmaceutical preparation, particularly a kind of use " inner disease outer treat " method in patient's SHANZHONG acupoint, is used for the treatment of the Chinese herbs paste of tracheitis, pneumonia, asthma with medicament plaster---and cough with asthma pastes Liu.

Infantile asthma is one of common disease in children, be secondary to more the flu after or concurrent in other lysis.The four seasons all can take place, and see in winter, spring more, and baby below three years old, child Geng Yi take place.

Its pathogeny is that children's's internal organs is dirty tender and lovely, and shape gas does not fill, and resistance is poor, so being invaded by exogenous pathogen is invaded in lung, makes the lung qi impatency and expectorant heat takes place, and the air flue that is jammed must not be declared logically, thereby superinverse is closed symptom so heating, cough, asthma, a series of lungs of flaring of nares occur.A surname send out with respectful falling be the major physiological function of lung, the main pathological change of lung also be Xuan Fasu fall not normal, ascending or descending movement of vital Qi is lacked of proper care.Treatment should be that the contrary person of Yu Zhexuan falls.Therefore treating that pneumonia separates heat extraction, expectorant, breathes heavily is the key of clinical diagnosis and treatment, and disease controlling development in time often prevents that disease from growing thickly.A surname falls so treatment tracheitis, pneumonia, asthma adopt, heat clearing away, reduce phlegm, blood circulation promoting and blood stasis dispelling, catharsis method be as the be born major measure of reason function of the Xuan Fasu that recovers lung.The generation development of pneumonia is extremely complicated pathological process, use a certain method of treatment often to be difficult for getting a desired effect merely, thereby clinical use in conjunction can improve curative effect.

Its Therapeutic Method, doctor trained in Western medicine mainly are to use heavy dose of multiple broad ectrum antibiotic, though symptomatic treatment has certain curative effect, " uncharm merely.Ignore " setting upright ", often get half the result with twice the effort, thereby the common course of treatment is longer, expense is more expensive, and certain toxic and side effects is arranged inevitably.The Chinese medicine employing " treating both the principal and secondary aspects of a disease " of curing the disease is better consolidated toward living curative effect, still, traditional Chinese herbs decoction bitter in the mouth, the ball of Chinese patent medicine, the produce effects of loosing wait deficiency more slowly, especially to the baby of the above-mentioned all diseases of susceptible, child's administration difficulty, infant and family members are difficult for accepting.

Purpose of the present invention, be exactly according to traditional Chinese medical theory and experience, improve the deficiency of its dosage form again, traditional meridians effect is combined with drug influence, imitate the i.e. method of " inner disease outer treat " outward in inviting, be used for the treatment of tracheitis, pneumonia, asthma, and a kind of new Chinese medicine preparation-plaster for curing cough with dyspnea of development.Maximize favourable factors and minimize unfavourable ones, both brought into play Chinese medicine mark, this doublely controls, the strong point of the overall view overall situation, makes again that its produce effects is fast, short treating period, cost saving, the novel formulation of quick-acting, convenient, safe, the inexpensive and no pain that little infant is suitable for especially.

The objective of the invention is to implement by the following technical programs:

A kind of plaster for curing cough with dyspnea of development and design, it

(1) be pure Chinese medicinal preparation,

(2) used medical material can be selected from following kind:

Herba Houttuyniae, Herba Ephedrae, Semen Lepidii (Semen Descurainiae), Fructus Gardeniae, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Semen Armeniacae Amarum, Radix Glycyrrhizae, Fructus Perillae, Radix Scutellariae, Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Radix Platycodonis and Radix Et Rhizoma Rhei.

(3) quantity of used each medical material can be selected in following share:

10～15 parts of Herba Houttuyniae, 5～12 parts in Herba Ephedrae, 5～15 parts of Semen Lepidii (Semen Descurainiae)s, 5～12 parts of Fructus Gardeniaes, 5～10 parts of the Rhizoma Pinelliaes, 5～10 parts of Pericarpium Citri Reticulataes, 5～12 parts in Semen Armeniacae Amarum, 5～10 parts in Radix Glycyrrhizae, 5～15 parts of Fructus Perillaes, 5～12 parts of Radix Scutellariaes, 5～10 parts of Radix Platycodoniss, 5～13 parts of Rhizoma Curcumae, 10～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Radix Et Rhizoma Rhei.

Above-mentioned Adhesive plaster capable of detoxicating and resolving a mass, its dosage form can be the powder that rubber-emplastrum or use rubber plaster are applied ointment or plaster as carrier.

Above-mentioned Adhesive plaster capable of detoxicating and resolving a mass, its application site is a SHANZHONG acupoint.

The preparation of the following medical material of a kind of usefulness is as the application of the Chinese herbs paste of treatment tracheitis, pneumonia, asthma, it is characterized in that the kind of used each medical material and quantity can select in following share:

10～15 parts of Herba Houttuyniae, 5～12 parts in Herba Ephedrae, 5～15 parts of Semen Lepidii (Semen Descurainiae)s, 5～12 parts of Fructus Gardeniaes, 5～10 parts of the Rhizoma Pinelliaes, 5～10 parts of Pericarpium Citri Reticulataes, 5～12 parts in Semen Armeniacae Amarum, 5～10 parts in Radix Glycyrrhizae, 5～15 parts of Fructus Perillaes, 5～12 parts of Radix Scutellariaes, 5～10 parts of Radix Platycodoniss, 5～13 parts of Rhizoma Curcumae, 10～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Radix Et Rhizoma Rhei.

After above-mentioned each Chinese crude drug pressed the preliminary election of Chinese Pharmacopoeia prescriptive procedure, roguing respectively, former medicated powder is broken, sieve or through extracting, remove slag, concentrate, making extractum behind the precipitate with ethanol, compatibility is concocted by the powder of Chinese Pharmacopoeia rules of preparations regulation or the requirement of rubber-emplastrum respectively to scale.

The extraction of each above-mentioned Chinese crude drug, its solvent can be water or medicinal alcohol; Its extracting method can be to reflux or decoction.

Modern pharmacology shows that lung qi dispersing is main Herba Ephedrae, the little hardship of its acrid in the mouth warm in nature, and the wide determined curative effect of effect by diaphoresis, analgesic, antiviral, is removed bronchospasm, antiinflammatory, and antiallergic reduces the swelling of bronchial mucosa, reaches depressed lung-energy dispersing.Herba Houttuyniae has stronger inhibitory action to staphylococcus aureus, contains quercimentin and potassium salt simultaneously, diuresis and blood vessel dilating.Rhizoma Curcumae treatment infantile pneumonia has good effect, and blood circulation promoting and blood stasis dispelling is antibiotic, respiratory syncytial virus, influenza virus is had suppress and deactivation, has no side effect.Radix Salviae Miltiorrhizae has the Absorption that quickens the alleviation of severe pneumonia cardinal symptom and promote pulmonary rale, can make accumulative erythrocyte depolymerization, quickens microcirculatory circulation, and improves the ability of tissue picked-up oxygen from microcirculation.The Semen Lepidii (Semen Descurainiae) eliminating the pathogens from the lung is reduced phlegm, and it is respectful that lung qi is declared, and expectorant is stopped up in pulmonary cough breathed heavily effectively.Rhizoma Pinelliae energy stomach function regulating preventing or arresting vomiting, removing dampness and eliminating phlegm, mass dissipating and swelling eliminating.The Pericarpium Citri Reticulatae invigorating the stomach and resolving phlegm is joined the Rhizoma Pinelliae and can be strengthened the effect that drying dampness to eliminate phlegm is relievingd asthma.The animal experiment prompting, Radix Et Rhizoma Rhei can make skin capillary vascular expansion, and heat radiation increases, and reduces nervus centralis media-prostaglandin level, and this is the mechanism of the analgesic cooling of Radix Et Rhizoma Rhei.Radix Et Rhizoma Rhei also has antibacterial, antiviral, antiinflammatory, calmness and promotes the function of immunity.Bringing down a fever of Radix Et Rhizoma Rhei may be to cause the whole body conditioned reaction by local excitation.

Radix Et Rhizoma Rhei, Radix Scutellariae, Fructus Gardeniae, Herba Houttuyniae, Radix Salviae Miltiorrhizae, all medicine heat-clearing and toxic substances removing of Rhizoma Curcumae, it is logical to invigorate blood circulation.According to the research of modern medicine, this class medicine phase 5, not only the may command pulmonary infection improves the microcirculation of lung, and can promote the discharge to lung microcirculation harmful toxins.One a surname one falls and impels lung qi unobstructed, is the key of we's composition.All medicines share depressed lung-energy dispersing, antiinflammatory, and spasmolytic, antiallergic is eliminated the phlegm, and antitussive is improved pulmonary's microcirculation, promotes inflammation to absorb.

SHANZHONG acupoint is the centrostigma of the intensive opening of microcirculation.Adopt " inner disease outer treat " to treat above-mentioned disease herein in the plaster for curing cough with dyspnea of the present invention's development of applying ointment or plaster, be the theory that embodies " calentura is the interior person; the air pocket of getting its meeting also " of the traditional Chinese medical science, the effective biological activity and the meridians Yu cave itself that make full use of Chinese medicine have quick property and enlarge-effect outward.

Clinical pneumonia 1200 examples, the total effective rate 95% of being used for the treatment of.

The some cases broad ectrum antibiotic is the contrast medication, and the result is as follows:

A plaster for curing cough with dyspnea group B broad ectrum antibiotic group

Heating retreated to normal time 1～2 day 4～7 days

Cough with asthma is alleviated medication 4h and is taken a turn for the better

Obviously alleviate 7～10 days about two days

About 5 days clinical cure time about 15 days

" B " group that " A " group obviously is better than contrasting.Viral pneumonia particularly, B group effect is poorer.

Facts have proved with plaster for curing cough with dyspnea of the present invention to be applied to patient's SHANZHONG acupoint that treatment tracheitis, pneumonia have the following advantages:

1. quick-acting

Bring down a fever, instant effect is breathed heavily in cough-relieving, general medication 4h left and right sides onset, and three days left and right sides produce effects, total effective rate reaches 95%.

2. convenient

Inner disease outer treat is applied to patient's SHANZHONG acupoint with plaster for curing cough with dyspnea, need not to take medicine and has an injection, and no pain saves time and produce effects.

3. safety

Belong to pure Chinese medicinal preparation, do not find toxic and side effects through clinical verification for many years.

4. inexpensive

For treatment tracheitis, pneumonia, generally only cost with about 40 yuan, and conventional doctor trained in Western medicine hospitalization needs about 300 yuan approximately, expense saves 80～90%.

5. market prospect is wide

According to the retrieval, not seeing has so quick-acting, convenient, the safe drugs of the above-mentioned disease of treatment, is specially adapted to have an injection, the take medicine inconvenient wide rural area patient and the infant of administration difficulty.

Social benefit and remarkable in economical benefits have reached intended purposes of the present invention preferably.

The present invention is further elaborated below in conjunction with embodiment:

[embodiment one] preparation cough with asthma powder, in following ratio compatibility:

Concrete principal agent is:

Herba Ephedrae 12g, Semen Lepidii (Semen Descurainiae) 15g, Rhizoma Pinelliae 10g, Semen Armeniacae Amarum 12g, Radix Glycyrrhizae 5g, Radix Scutellariae 12g, Radix Platycodonis 5g, Rhizoma Curcumae 13g, Radix Et Rhizoma Rhei 10g, Pericarpium Citri Reticulatae 5g.

Technical process:

The above-mentioned batch of all medical material of dosage, conventional drying are to moisture content≤5%, and fusion also is crushed to fine powder, cross 100 mesh sieves, low temperature sterilization, and packing is divided two kinds, and it is a bag that children's packs every 0.3g: the every 0.6g of adult's packing is a bag.

Check projects such as the uniformity, moisture content, content uniformity qualified by the pharmacopeia requirement after, warehouse-in.

Usage, consumption

Be used for the treatment of infantile asthma, once measure children's and pack 1 bag; Be used for the treatment of adult's cough with asthma, once amount adult packing 1 bag.All be to stick in SHANZHONG acupoint with adhesive plaster, 24h changes dressings once.

[embodiment two] preparation cough with asthma rubber-emplastrum, in following ratio compatibility:

Concrete principal agent is:

Herba Houttuyniae 15g, Herba Ephedrae 12g, Rhizoma Pinelliae 10g, Pericarpium Citri Reticulatae 10g, Semen Armeniacae Amarum 12g, Radix Glycyrrhizae 10g, Radix Salviae Miltiorrhizae 15g, Radix Et Rhizoma Rhei 5g.

Technical process:

1. Chinese crude drug is made fine powder or medicinal extractum with example one;

2. use substrate, softening agent, thickening agent and the filler of pharmacopeia regulation:

3. be coated with " mixing " operation adding drug extract of exhibition method, substrate, softening agent, thickening agent and the filler etc. of pharmacopeia regulation in hot pressing, press conventional method refine, gluing, the section of pharmacopeia regulation:

4. by projects such as pharmacopeia requirement check outward appearance, paste containing amount, heat resistant tests;

5. qualified back packing.

Usage, consumption

Be used for the treatment of tracheitis, pneumonia, asthma, more than two years old, once pack 1 (being equivalent to principal agent 35mg) with children's, packed half sheet with children's to one-year-old person in 6 months at every turn, 12h changes dressings once; Be used for the treatment of adult's tracheitis, pneumonia, once pack 1 (being equivalent to principal agent 40mg) with the adult, 12h changes dressings once, all is to stick in SHANZHONG acupoint.

[embodiment three] preparation cough with asthma powder, in following ratio compatibility:

Concrete principal agent is:

Herba Houttuyniae 15g, Herba Ephedrae 12g, Semen Lepidii (Semen Descurainiae) 15g, Semen Armeniacae Amarum 5g, Fructus Perillae 15g, Radix Scutellariae 12g, Rhizoma Curcumae 13g.

Technology, condition, usage, consumption etc. are all with embodiment one.

[embodiment four] preparation cough with asthma rubber-emplastrum, in following ratio compatibility:

Principal agent is:

Herba Ephedrae 12, Semen Lepidii (Semen Descurainiae) 15g, Fructus Gardeniae 5g, Rhizoma Pinelliae 5g, Semen Armeniacae Amarum 12g, Radix Glycyrrhizae 10g, Radix Scutellariae 12g, Radix Platycodonis 5g, Rhizoma Curcumae 5g, Radix Salviae Miltiorrhizae 15g.

Technology, condition, usage, consumption etc. are all with embodiment two.

[embodiment five] preparation detoxicating and resolving stagnation of pathogens rubber-emplastrum, in following ratio compatibility:

Concrete principal agent is:

Herba Houttuyniae 10g, Herba Ephedrae 5g, Fructus Gardeniae 12g, Semen Lepidii (Semen Descurainiae) 50g, Pericarpium Citri Reticulatae 10g, Semen Armeniacae Amarum 12g, Radix Glycyrrhizae 5g, Fructus Perillae 5g, Radix Scutellariae 5g, Radix Platycodonis 10g, Radix Salviae Miltiorrhizae 10g.

Technology, condition, usage, consumption etc. are all with embodiment two.

Claims (1)

1. Chinese herbs paste for the treatment of tracheitis, pneumonia is characterized in that: it is that component with following consumption is that raw material is made:

Herba Ephedrae 12g, Semen Lepidii (Semen Descurainiae) 15g, Rhizoma Pinelliae 10g, Semen Armeniacae Amarum 12g, Radix Glycyrrhizae 5g, Radix Scutellariae 12g, Radix Platycodonis 5g, Rhizoma Curcumae 13g, Radix Et Rhizoma Rhei 10g, Pericarpium Citri Reticulatae 5g.