CN114431298A - Modified milk powder and preparation method thereof - Google Patents
Modified milk powder and preparation method thereof Download PDFInfo
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- CN114431298A CN114431298A CN202210196684.1A CN202210196684A CN114431298A CN 114431298 A CN114431298 A CN 114431298A CN 202210196684 A CN202210196684 A CN 202210196684A CN 114431298 A CN114431298 A CN 114431298A
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- 235000013336 milk Nutrition 0.000 title claims abstract description 77
- 239000008267 milk Substances 0.000 title claims abstract description 77
- 210000004080 milk Anatomy 0.000 title claims abstract description 77
- 239000000843 powder Substances 0.000 title claims abstract description 67
- 238000002360 preparation method Methods 0.000 title abstract description 57
- 235000015097 nutrients Nutrition 0.000 claims abstract description 49
- 150000001875 compounds Chemical class 0.000 claims abstract description 23
- 229940088594 vitamin Drugs 0.000 claims abstract description 22
- 229930003231 vitamin Natural products 0.000 claims abstract description 22
- 235000013343 vitamin Nutrition 0.000 claims abstract description 22
- 239000011782 vitamin Substances 0.000 claims abstract description 22
- 241000894006 Bacteria Species 0.000 claims abstract description 19
- 150000003839 salts Chemical class 0.000 claims abstract description 19
- 230000009286 beneficial effect Effects 0.000 claims abstract description 18
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract description 13
- 108010046377 Whey Proteins Proteins 0.000 claims abstract description 12
- 102000007544 Whey Proteins Human genes 0.000 claims abstract description 12
- 239000008101 lactose Substances 0.000 claims abstract description 12
- 239000005862 Whey Substances 0.000 claims abstract description 11
- 102100026189 Beta-galactosidase Human genes 0.000 claims abstract description 10
- 108010059881 Lactase Proteins 0.000 claims abstract description 10
- 108010005774 beta-Galactosidase Proteins 0.000 claims abstract description 10
- 229940116108 lactase Drugs 0.000 claims abstract description 10
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 32
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 26
- 235000020185 raw untreated milk Nutrition 0.000 claims description 24
- 238000003756 stirring Methods 0.000 claims description 21
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 claims description 16
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 claims description 16
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 claims description 16
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims description 16
- 229960001231 choline Drugs 0.000 claims description 16
- 229960003512 nicotinic acid Drugs 0.000 claims description 16
- 235000001968 nicotinic acid Nutrition 0.000 claims description 16
- 239000011664 nicotinic acid Substances 0.000 claims description 16
- 150000002337 glycosamines Chemical class 0.000 claims description 15
- 239000002773 nucleotide Substances 0.000 claims description 14
- 125000003729 nucleotide group Chemical group 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 13
- 229960003080 taurine Drugs 0.000 claims description 13
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 12
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- 238000005303 weighing Methods 0.000 claims description 10
- 235000020603 homogenised milk Nutrition 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 8
- 238000001694 spray drying Methods 0.000 claims description 8
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 7
- 241000901050 Bifidobacterium animalis subsp. lactis Species 0.000 claims description 7
- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 claims description 7
- 229940009289 bifidobacterium lactis Drugs 0.000 claims description 7
- 239000004227 calcium gluconate Substances 0.000 claims description 7
- 229960004494 calcium gluconate Drugs 0.000 claims description 7
- 235000013927 calcium gluconate Nutrition 0.000 claims description 7
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 7
- 235000013925 ferrous lactate Nutrition 0.000 claims description 7
- 239000004225 ferrous lactate Substances 0.000 claims description 7
- 229940037907 ferrous lactate Drugs 0.000 claims description 7
- 239000000787 lecithin Substances 0.000 claims description 7
- 229940067606 lecithin Drugs 0.000 claims description 7
- 235000010445 lecithin Nutrition 0.000 claims description 7
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 6
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 6
- 241000218588 Lactobacillus rhamnosus Species 0.000 claims description 6
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 6
- 229930003268 Vitamin C Natural products 0.000 claims description 6
- 229930003316 Vitamin D Natural products 0.000 claims description 6
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
- 229930003448 Vitamin K Natural products 0.000 claims description 6
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 6
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims description 6
- 230000001954 sterilising effect Effects 0.000 claims description 6
- 235000019155 vitamin A Nutrition 0.000 claims description 6
- 239000011719 vitamin A Substances 0.000 claims description 6
- 239000011716 vitamin B2 Substances 0.000 claims description 6
- 239000011726 vitamin B6 Substances 0.000 claims description 6
- 235000019154 vitamin C Nutrition 0.000 claims description 6
- 239000011718 vitamin C Substances 0.000 claims description 6
- 235000019166 vitamin D Nutrition 0.000 claims description 6
- 239000011710 vitamin D Substances 0.000 claims description 6
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 6
- 235000019168 vitamin K Nutrition 0.000 claims description 6
- 239000011712 vitamin K Substances 0.000 claims description 6
- 150000003721 vitamin K derivatives Chemical class 0.000 claims description 6
- 229940045997 vitamin a Drugs 0.000 claims description 6
- 229940046008 vitamin d Drugs 0.000 claims description 6
- 229940046010 vitamin k Drugs 0.000 claims description 6
- 229930003427 Vitamin E Natural products 0.000 claims description 5
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 5
- 235000019165 vitamin E Nutrition 0.000 claims description 5
- 239000011709 vitamin E Substances 0.000 claims description 5
- 229940046009 vitamin E Drugs 0.000 claims description 5
- 229930003270 Vitamin B Natural products 0.000 claims description 3
- 238000004140 cleaning Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 238000000746 purification Methods 0.000 claims description 3
- 235000019156 vitamin B Nutrition 0.000 claims description 3
- 239000011720 vitamin B Substances 0.000 claims description 3
- 239000011691 vitamin B1 Substances 0.000 claims description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 2
- 229960001375 lactose Drugs 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 claims description 2
- 235000020122 reconstituted milk Nutrition 0.000 claims 1
- 238000011161 development Methods 0.000 abstract description 34
- 239000002994 raw material Substances 0.000 abstract description 28
- 230000001537 neural effect Effects 0.000 abstract description 8
- 230000001737 promoting effect Effects 0.000 abstract description 4
- 235000020247 cow milk Nutrition 0.000 abstract 1
- 235000013350 formula milk Nutrition 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 description 33
- 241000700159 Rattus Species 0.000 description 24
- 230000000052 comparative effect Effects 0.000 description 11
- 239000002131 composite material Substances 0.000 description 10
- 230000000694 effects Effects 0.000 description 10
- 210000001035 gastrointestinal tract Anatomy 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 241000699666 Mus <mouse, genus> Species 0.000 description 5
- 210000000653 nervous system Anatomy 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 239000006041 probiotic Substances 0.000 description 4
- 235000018291 probiotics Nutrition 0.000 description 4
- 150000003722 vitamin derivatives Chemical class 0.000 description 4
- 230000032823 cell division Effects 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 235000020248 camel milk Nutrition 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000011552 falling film Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000003988 neural development Effects 0.000 description 2
- 239000002858 neurotransmitter agent Substances 0.000 description 2
- 230000000529 probiotic effect Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 235000020244 animal milk Nutrition 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004958 brain cell Anatomy 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 235000014121 butter Nutrition 0.000 description 1
- 229960005069 calcium Drugs 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 230000025402 cranial nerve development Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 description 1
- 229940107187 fructooligosaccharide Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000030363 nerve development Effects 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000005979 thermal decomposition reaction Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1522—Inorganic additives, e.g. minerals, trace elements; Chlorination or fluoridation of milk; Organic salts or complexes of metals other than natrium or kalium; Calcium enrichment of milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1526—Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/158—Milk preparations; Milk powder or milk powder preparations containing additives containing vitamins or antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dairy Products (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The application relates to the technical field of milk powder, and particularly discloses modified milk powder and a preparation method thereof. The infant formula milk powder comprises raw materials of cow milk, desalted whey powder, lactose, organic salt, beneficial bacteria, vitamins, lactase and compound nutrients in parts by weight, and has the advantage of promoting the neural intelligence development of infants.
Description
Technical Field
The application relates to the technical field of milk powder, in particular to modified milk powder and a preparation method thereof.
Background
The milk powder is powder formed by removing water from milk or camel milk and drying the milk or camel milk, at present, in order to meet the requirements of clients of different ages and different types during the production of the milk powder, other nutrient elements are usually added into the concentrated animal milk powder, so that the functions of the milk powder are enriched, the consumption requirements of different consumers are met, the milk powder added with other nutrient elements is also called modified milk powder, and most of the milk powder on the market is modified milk powder at present.
The related Chinese application with publication number CN111184071A discloses a modified milk powder, which is prepared from the following raw materials in parts by weight: 20-30 parts of milk powder, 15-25 parts of butter powder, 5-10 parts of concentrated whey protein, 5-10 parts of maltodextrin, 5-8 parts of fructo-oligosaccharide, 3-5 parts of lactase and 3-5 parts of lactic acid bacteria.
In view of the above-mentioned related technologies, the inventors believe that when the modified milk powder is used for feeding infants, it is difficult to meet the requirements of the infants for growth and development, and further, the development of the infant's neural intelligence is not facilitated.
Disclosure of Invention
The application provides modified milk powder and a preparation method thereof in order to promote the development of neural intelligence of infants.
In a first aspect, the modified milk powder provided by the application adopts the following technical scheme:
preparing milk powder, wherein the preparation raw materials comprise, by weight, 400-520 parts of raw milk, 20-30 parts of desalted whey powder, 20-30 parts of lactose, 1-2 parts of organic salt, 0.02-0.05 part of beneficial bacteria, 0.03-0.06 part of vitamin, 1-2 parts of lactase and 2-4 parts of compound nutrient.
By adopting the technical scheme, the nutrient elements in the modified milk powder can fully meet the requirements of the growth and development of infants, and particularly can promote the development of the neural intelligence of the infants; the raw materials of the milk and the lactose can provide most energy for the infants so as to meet the energy consumption of the physiological activities of the infants, and the desalted whey is added to improve the content of the nutrient elements in the modified milk powder, reduce the content of salt in the modified milk powder and reduce the adverse effect on the growth and development of the infants; lactase can promote the decomposition of lactose and play a certain role in caring the delicate intestinal tracts of infants; after the probiotics are added, the probiotics can inhibit the propagation of harmful bacteria in the intestinal tract of the infant, are beneficial to maintaining the micro-ecological balance of the intestinal tract system and are convenient for fully absorbing nutrient substances; the addition of organic salt and vitamins is convenient for providing the infants with trace elements necessary for growth and development; the compound nutrient elements can provide necessary substances for the development of infant nerves, can promote the rapid development of infant nervous systems, and reduces the problem of slow development of infant neural intelligence.
Preferably, the compound nutrient comprises 1.2 parts of nicotinic acid, 12 parts of choline and 8 parts of taurine in parts by weight.
By adopting the technical scheme, after the infants absorb the nicotinic acid and the choline, the nicotinic acid and the choline have synergistic effect to promote the secretion of neurotransmitter so as to stimulate the development of a nervous system, and the taurine can promote the development of brain tissues of the infants and promote the division and proliferation of brain cells after being absorbed by the infants so as to be beneficial to the development of neural intelligence of the infants.
Preferably, the compound nutrient further comprises 16 parts of ribose, 10 parts of amino sugar and 20 parts of nucleotide by weight.
By adopting the technical scheme, the ribose and the nucleotide are indispensable substances during cell division, and the ribose, the nucleotide and the amino sugar are added into the prepared milk powder to effectively promote the cell division, so that the neural intelligence development of infants can be promoted.
Preferably, the organic salt comprises, by weight, 4 parts of calcium gluconate, 10 parts of lecithin and 7 parts of ferrous lactate.
By adopting the technical scheme, the calcium gluconate, the lecithin and the ferrous lactate can promote the growth and development of the infants, can provide necessary trace elements for the growth and development of the infants, and calcium, phosphorus and iron are added in an organic form, so that the absorption of intestinal tracts is facilitated.
Preferably, the beneficial bacteria comprise 6 parts of bifidobacterium lactis and 2 parts of lactobacillus rhamnosus in parts by weight.
By adopting the technical scheme, the bifidobacterium lactis and the rhamnose bacillus are matched, so that the flora in the intestinal tract of the infant can be adjusted, the pH balance in the intestinal tract can be adjusted, the development of the intestinal mucosa can be promoted, and the absorption of the nutrient elements by the infant can be facilitated.
Preferably, the vitamins comprise 100 parts of vitamin A, 4 parts of vitamin D, 5 parts of vitamin E, 1 part of vitamin K, 7 parts of vitamin C and 220 parts of vitamin B in parts by weight1310 portions of vitamin B2And 25 parts of vitamin B6。
By adopting the technical scheme, the basic requirements of the infant on the vitamins can be met by the proportion of the vitamins, and the vitamins can be fully absorbed by the infant by adopting the proportion.
In a second aspect, the present application provides a method for preparing a modified milk powder, which adopts the following technical scheme:
the preparation method of the modified milk powder comprises the following steps:
s1: checking and accepting raw milk;
s2: cleaning milk: filtering raw milk, and purifying to ensure that the impurity degree is less than or equal to 2 ppm;
s3: and (3) refrigerating: refrigerating the raw milk after milk purification, wherein the refrigerating temperature is less than or equal to 4 ℃, and stirring the raw milk during refrigerating;
s4: and (3) standardization: weighing desalted whey powder, lactose, calcium gluconate, lecithin, ferrous lactate, Bifidobacterium lactis, Lactobacillus rhamnosus, vitamin A, vitamin D, vitamin E, vitamin K, vitamin C and vitamin B according to a certain proportion1Vitamin B2Vitamin B6Lactase, nicotinic acid, choline, taurine, ribose, amino sugar and nucleotide, and adding the substances into the raw milk refrigerated in S3;
s5: homogenizing: adding the raw milk with the auxiliary materials added in the S4 into a high-pressure homogenizer, and homogenizing to obtain homogenized milk;
s6: sterilizing, namely sterilizing the homogenized milk;
s7: concentrating, namely concentrating the sterilized homogenized milk to obtain concentrated milk;
s8: spray drying, namely spray drying the concentrated milk to obtain milk powder;
s9: cooling, and cooling the coarse milk powder obtained in S8 to obtain a modified milk powder.
By adopting the technical scheme, the process for processing the prepared milk powder is simple and has high preparation efficiency.
Preferably, the maximum temperature is not higher than 175 ℃ when the concentrated milk is dried in S8.
By adopting the technical scheme, the drying temperature is controlled below 175 ℃, so that the problem of thermal decomposition of heat-sensitive substances can be reduced, and the nutrients are further reserved.
In summary, the present application has the following beneficial effects:
1. because the milk, the desalted whey powder, the lactose, the organic salt, the beneficial bacteria, the vitamins, the lactase and the compound nutrients are adopted as raw materials, the compound of all the elements has higher absorptivity, and necessary nutrient elements can be provided for the development of infants, the requirement of the development of the infant nervous system can be met, the rapid development of the infant nervous system can be further promoted, and the problem of the slow development of the infant neural intelligence is solved.
2. The compound nutrient contains nicotinic acid, choline, taurine, ribose, aminosugar and nucleotide, and nicotinic acid, choline, taurine, ribose, aminosugar and nucleotide can promote cell division and proliferation, and can improve neurotransmitter secretion, and then promote the development of nerve cells, consequently can further promote infant nervous system's rapid development.
Detailed Description
The present application will be described in further detail with reference to examples.
The raw materials used in the preparation examples and the examples are all commercially available products which accord with the food sanitation law of the people's republic of China.
Preparation example
Examples of preparation of organic salts
Weighing 4 kg of calcium gluconate, 10 kg of lecithin and 7 kg of ferrous lactate, adding the calcium gluconate, the lecithin and the ferrous lactate into a mixer, starting the mixer to mix the raw materials, wherein the stirring speed is 80r/min, the stirring time is 20min, and after the stirring is finished, closing the mixer to obtain the organic salt serving as the mixed substance.
Preparation of beneficial bacteria
Weighing 6 kg of bifidobacterium lactis and 2 kg of lactobacillus rhamnosus, adding the bifidobacterium lactis and the lactobacillus rhamnosus into a mixer, starting the mixer to mix the raw materials, wherein the stirring speed is 50r/min, the stirring time is 30min, and after stirring is finished, closing the mixer to obtain a mixed substance which is beneficial bacteria.
Vitamin preparation example
Weighing 100 kg of vitaminsComprises 4 kg of vitamin A, 5 kg of vitamin D, 1 kg of vitamin K, 7 kg of vitamin C and 220 kg of vitamin B1310 kg of vitamin B2And 25 kg of vitamin B6Mixing vitamin A, vitamin D, vitamin E, vitamin K, vitamin C, and vitamin B1Vitamin B2And vitamin B6Adding into a mixer, starting the mixer to mix the raw materials, wherein the stirring speed is 100r/min, the stirring time is 15min, and after the stirring is finished, closing the mixer to obtain a mixed substance, namely the vitamin.
Preparation of Complex Nutrients
Preparation of Complex Nutrients example 1
Weighing 1.2 kg of nicotinic acid, 12 kg of choline and 8 kg of taurine, adding the nicotinic acid, the choline and the taurine into a mixer, starting the mixer to mix the raw materials, wherein the stirring speed is 500r/min, the stirring time is 40min, and after the stirring is finished, closing the mixer to obtain a mixed substance which is the composite nutrient.
Preparation of Complex Nutrients example 2
Weighing 16 kg of ribose, 10 kg of amino sugar and 20 kg of nucleotide, adding the ribose, the amino sugar and the nucleotide into a mixer, starting the mixer to mix the raw materials, wherein the stirring speed is 500r/min, the stirring time is 40min, and after the stirring is finished, closing the mixer to obtain a mixed substance, namely the composite nutrient.
Preparation of Complex Nutrients example 3
Weighing 1.2 kg of nicotinic acid, 12 kg of choline, 8 kg of taurine, 16 kg of ribose, 10 kg of aminosugar and 20 kg of nucleotide, adding the nicotinic acid, the choline, the taurine, the ribose, the aminosugar and the nucleotide into a mixer, starting the mixer to mix the raw materials, wherein the stirring speed is 500r/min, the stirring time is 40min, and after the stirring is finished, closing the mixer to obtain the mixed substance, namely the composite nutrient.
Preparation of Complex Nutrients example 4
The preparation example is different from the compound nutrient preparation example 1 in that the raw materials do not contain nicotinic acid and choline, and the formula and the process parameters of the rest raw materials are the same as those of the compound nutrient preparation example 1.
Preparation of Complex Nutrients example 5
The difference between the preparation example and the compound nutrient preparation example 2 is that the raw materials do not contain ribose and amino sugar, and the formula and the process parameters of the rest raw materials are the same as those of the compound nutrient preparation example 2.
Examples
Example 1
The preparation method of the modified milk powder comprises the following steps:
s1: checking and accepting the raw milk, and purchasing after the raw milk is detected to be qualified according to GB 19301-2010;
s2: cleaning milk: filtering raw milk, and purifying to ensure that the impurity degree is less than or equal to 2 ppm;
s3: and (3) refrigerating: refrigerating the raw milk after milk purification, wherein the refrigerating temperature is less than or equal to 4 ℃, and stirring the raw milk during refrigerating;
s4: and (3) standardization: weighing 20 kg of desalted whey powder, 20 kg of lactose, 1 kg of organic salt, 0.02 kg of beneficial bacteria, 0.03 kg of vitamins obtained in the vitamin preparation example, 1 kg of lactase and 2 kg of compound nutrients obtained in the compound nutrient preparation example 1, weighing 400 kg of raw milk, and adding the desalted whey powder, the lactose, the organic salt, the beneficial bacteria, the vitamins, the lactase and the compound nutrients into the raw milk;
s5: homogenizing: adding the raw milk with the auxiliary materials added in the S4 into a high-pressure homogenizer at the homogenizing pressure of 12MPa, and carrying out homogenizing treatment to obtain homogenized milk;
s6: sterilizing, namely sterilizing the homogenized milk by adopting a triple-effect falling film evaporator at the temperature of 88 +/-3 ℃ for 24 seconds;
s7: concentrating, namely concentrating the sterilized homogenized milk by adopting a triple-effect falling film evaporator at the temperature of 65-75 ℃ in a first effect, 55-65 ℃ in a second effect and 45-55 ℃ in a third effect respectively to obtain concentrated milk;
s8: spray drying, namely spray drying the concentrated milk by adopting a vertical pressure spray drying tower, controlling the air inlet temperature of the drying tower at 160 ℃, exhausting air at 75 ℃, keeping the negative pressure in the tower at-4-0 Pa and the temperature in the tower at 80 ℃ to obtain milk powder after spray drying;
s9: and (4) cooling, namely cooling the coarse milk powder obtained in the step (S8), performing cooling operation by adopting a three-stage fluidized bed, and obtaining the prepared milk powder after cooling.
Example 2
This example differs from example 1 in that 25 kg of demineralized whey powder, 25 kg of lactose, 1.5 kg of organic salts obtained in the preparation of organic salts, 0.03 kg of probiotic bacteria obtained in the preparation of probiotic bacteria, 0.04 kg of vitamins obtained in the preparation of vitamins, 1.5 kg of lactase, 3 kg of composite nutrient obtained in preparation example 1 and 470 kg of raw milk were weighed and the remaining preparation steps and process parameters were the same as in example 1.
Example 3
This example differs from example 1 in that 30 kg of desalted whey powder, 30 kg of lactose, 2 kg of organic salts obtained from the preparation of organic salts, 0.05 kg of beneficial bacteria obtained from the preparation of beneficial bacteria, 0.06 kg of vitamins obtained from the preparation of vitamins, 2 kg of lactase, 4 kg of composite nutrients obtained from preparation example 1 and 520 kg of raw milk were weighed and the rest of the preparation steps were the same as in example 1.
Example 4
The difference between this example and example 1 is that 2 kg of the composite nutrient obtained in preparation example 2 was weighed, and the rest of raw material ratio, preparation steps and process parameters were the same as those in example 1.
Example 5
The difference between this example and example 1 is that 2 kg of the composite nutrient obtained in preparation example 3 were weighed, and the rest of raw material ratio, preparation steps and process parameters were the same as those in example 1.
Example 6
The difference between this example and example 1 is that 2 kg of the composite nutrient obtained in preparation example 4 was weighed, and the rest of raw material ratio, preparation steps and process parameters were the same as those in example 1.
Example 7
The difference between this example and example 1 is that 2 kg of the composite nutrient obtained in preparation example 5 were weighed, and the rest of raw material ratio, preparation steps and process parameters were the same as those in example 1.
Comparative example
Comparative example 1
The difference between the comparative example and the example 1 is that the raw materials do not contain compound nutrients, and the proportion of the rest raw materials, the preparation steps and the process parameters are the same as those of the example 1.
Comparative example 2
The difference between the comparative example and the example 1 is that the raw materials do not contain organic salt, and the ratio of the rest raw materials, the preparation steps and the process parameters are the same as those of the example 1.
Comparative example 3
The difference between the comparative example and the example 1 is that the raw materials do not contain beneficial bacteria, and the proportion of the rest raw materials, the preparation steps and the process parameters are the same as those of the example 1.
Comparative example 4
The difference between the comparative example and the example 1 is that the raw materials do not contain vitamins, and the proportion of the other raw materials, the preparation steps and the process parameters are the same as those of the example 1.
Application effect testing
Test samples: the modified milk powders 1 to 7 obtained in examples 1 to 7 were used as test samples, and the modified milk powders 1 to 4 obtained in comparative examples 1 to 4 were used as control samples.
The test method comprises the following steps: selecting a plurality of rat dams, enabling the rat dams to be pregnant on the same day, dissecting young rats from the bodies of the rat dams when the pregnancy period of the rat is 16 days, selecting 120 young rats from the young rats as test objects, dividing 10 young rats into 12 groups, feeding 1-7 groups with milk brewed from a prepared milk powder 1-7 test sample, feeding 8-11 groups with milk brewed from a prepared milk powder 1-3 control sample, feeding 12 groups with the milk of the rat dams, extruding the milk of the rat dams, feeding the milk of the rat dams to the young rats of the 12 groups to ensure that the daily feeding amount and the feeding frequency of each young rat in the 12 groups are the same, carrying out head MRI detection on the young rats after feeding for 5 days, 10 days and 15 days, recording the development condition of cranial nerves, and taking the average growth condition of the young rats of the 12 groups as a standard growth and development condition after each detection, in each group of young mice, 1 point is added to the group of young mice with the growth development condition superior to that of the 12 th group, 0 point is added close to the average growth development condition of the 12 th group, and 1 point is added to the group of young mice with the growth development condition inferior to that of the 12 th group of young mice, and the measurement results are calculated and recorded to obtain table 1.
TABLE 1 evaluation chart of cranial nerve development of young mouse
And (3) analyzing test results:
1. as can be seen from the combination of example 1 and table 1, after the compound nutrient prepared in preparation example 1 is added to the prepared milk powder, it can be seen from the experimental data that the brain nerve development of the young mouse fed with the compound nutrient in example 1 is better than that of the young mouse fed with the milk of the mother mouse after 5 days, which indicates that the compound nutrient prepared in preparation example 1 has a strong promoting effect on the growth and development of the young mouse;
2. as can be seen by combining examples 1 to 3 with Table 1, the effects of regulating the amounts of the respective nutrients within a certain range on the promotion of the neural development of rat pups are substantially the same;
3. as can be seen by combining examples 1 and 4 and table 1, the composite nutrients in the modified milk powder, which contain nicotinic acid, choline and taurine, and ribose, amino sugar and nucleotide, have substantially the same promoting effect on rats;
4. as can be seen from example 5 in combination with table 1, example 5 is the most preferable example, and thus it can be demonstrated that the promotion effect on the neural development of rat pups is the strongest when nicotinic acid, choline, taurine, ribose, amino sugar and nucleotide are contained in the complex nutrient;
5. as can be seen by combining examples 5-7 with Table 1, the growth-promoting effect on rat pups is poor when nicotinic acid and choline or ribose and amino sugar are absent in the complex nutrients, thus illustrating the synergistic effect of the substances of claims 2 and 3 on the development of rat pups nerves;
6. when the compound nutrient is not contained in the prepared milk powder, the promotion effect on the growth and development of the young rat is poor, and the growth and development of the rat and the young rat can be delayed to a certain extent;
7. as can be seen by combining example 1 and comparative examples 2 to 4 with Table 1, the effect of promoting the growth and development of rat pups was significantly inferior to that of example 1 when the formulated milk powder did not contain organic salts, beneficial bacteria and vitamins, indicating the essential ingredients in the formulation of milk powder containing organic salts, beneficial bacteria and vitamins.
The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.
Claims (8)
1. The modified milk powder is characterized by comprising, by weight, 520 parts of raw milk 400, 30 parts of desalted whey powder 20, 30 parts of lactose, 1-2 parts of organic salt, 0.02-0.05 part of beneficial bacteria, 0.03-0.06 part of vitamins, 1-2 parts of lactase and 2-4 parts of compound nutrients.
2. The modified milk powder of claim 1, wherein: the compound nutrient comprises 1.2 parts of nicotinic acid, 12 parts of choline and 8 parts of taurine in parts by weight.
3. The modified milk powder of claim 2, wherein: the compound nutrient further comprises 16 parts of ribose, 10 parts of amino sugar and 20 parts of nucleotide by weight.
4. The modified milk powder of claim 1, wherein: the organic salt comprises, by weight, 4 parts of calcium gluconate, 10 parts of lecithin and 7 parts of ferrous lactate.
5. The modified milk powder of claim 1, wherein: the beneficial bacteria comprise 6 parts of bifidobacterium lactis and 2 parts of lactobacillus rhamnosus in parts by weight.
6. The modified milk powder of claim 1, wherein: the vitamins comprise, by weight, 100 parts of vitamin A, 4 parts of vitamin D, 5 parts of vitamin E, 1 part of vitamin K, 7 parts of vitamin C and 220 parts of vitamin B1310 portions of vitamin B2And 25 parts of vitamin B6。
7. The method for preparing a reconstituted milk powder according to any one of claims 1 to 6, characterized in that: the method comprises the following steps:
s1: checking and accepting raw milk;
s2: cleaning milk: filtering raw milk, and purifying to ensure that the impurity degree is less than or equal to 2 ppm;
s3: and (3) refrigerating: refrigerating the raw milk after milk purification, wherein the refrigerating temperature is less than or equal to 4 ℃, and stirring the raw milk during refrigerating;
s4: and (3) standardization: weighing desalted whey powder, lactose, calcium gluconate, lecithin, ferrous lactate, Bifidobacterium lactis, Lactobacillus rhamnosus, vitamin A, vitamin D, vitamin E, vitamin K, vitamin C and vitamin B according to a certain proportion1Vitamin B2Vitamin B6Lactase, nicotinic acid, choline, taurine, ribose, amino sugar and nucleotide, and adding the substances into the raw milk refrigerated in S3;
s5: homogenizing: adding the raw milk with the auxiliary materials added in the S4 into a high-pressure homogenizer, and homogenizing to obtain homogenized milk;
s6: sterilizing, namely sterilizing the homogenized milk;
s7: concentrating, namely concentrating the sterilized homogenized milk to obtain concentrated milk;
s8: spray drying, namely spray drying the concentrated milk to obtain milk powder;
s9: cooling, and cooling the coarse milk powder obtained in S8 to obtain a modified milk powder.
8. The method for producing a modified milk powder according to claim 7, characterized in that: when the concentrated milk was dried in S8, the maximum temperature was not higher than 175 ℃.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101263840A (en) * | 2008-04-28 | 2008-09-17 | 内蒙古伊利实业集团股份有限公司 | Milk powder containing ribose and preparation thereof |
| CN104206539A (en) * | 2014-08-14 | 2014-12-17 | 澳优乳业（中国）有限公司 | Probiotic-containing infant milk powder |
| CN107897381A (en) * | 2017-12-28 | 2018-04-13 | 澳优乳业（中国）有限公司 | A kind of modulation milk powder of adjustment function of intestinal canal containing lactase and preparation method thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101263840A (en) * | 2008-04-28 | 2008-09-17 | 内蒙古伊利实业集团股份有限公司 | Milk powder containing ribose and preparation thereof |
| CN104206539A (en) * | 2014-08-14 | 2014-12-17 | 澳优乳业（中国）有限公司 | Probiotic-containing infant milk powder |
| CN107897381A (en) * | 2017-12-28 | 2018-04-13 | 澳优乳业（中国）有限公司 | A kind of modulation milk powder of adjustment function of intestinal canal containing lactase and preparation method thereof |
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