CN114402080B - 人巨细胞病毒的ul18对t细胞应答的调节 - Google Patents

人巨细胞病毒的ul18对t细胞应答的调节 Download PDF

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CN114402080B
CN114402080B CN202080064753.2A CN202080064753A CN114402080B CN 114402080 B CN114402080 B CN 114402080B CN 202080064753 A CN202080064753 A CN 202080064753A CN 114402080 B CN114402080 B CN 114402080B
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mhc
cells
seq
vector
recombinant hcmv
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CN114402080A (zh
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克劳斯·J·弗吕
斯克特·G·汉森
丹尼尔·马卢利
路易斯·J·皮克
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Oregon Health & Science University
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • C12N2710/16141—Use of virus, viral particle or viral elements as a vector
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CN202080064753.2A 2019-08-20 2020-08-19 人巨细胞病毒的ul18对t细胞应答的调节 Active CN114402080B (zh)

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US201962889310P 2019-08-20 2019-08-20
US62/889,310 2019-08-20
PCT/US2020/047050 WO2021034964A1 (en) 2019-08-20 2020-08-19 Modulation of t cell responses by ul18 of human cytomegalovirus

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US20240384296A1 (en) * 2021-08-31 2024-11-21 Vir Biotechnology, Inc. Recombinant hcmv vectors and uses thereof
WO2024059635A2 (en) * 2022-09-13 2024-03-21 Oregon Health And Science University Universal t cell-based, cmv-vectored vaccine for influenza

Citations (1)

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CN110036112A (zh) * 2016-10-18 2019-07-19 俄勒冈健康与科学大学 引发受主要组织相容性复合体e分子限制的t细胞的巨细胞病毒载体

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US1410314A (en) 1920-11-04 1922-03-21 Edgar B Hyatt Garage-door control
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US20020069244A1 (en) 1999-11-24 2002-06-06 John Blair Message delivery system billing method and apparatus
CA2437201C (en) * 2001-02-02 2008-11-18 Chemocentryx, Inc. Methods and compositions useful for stimulating an immune response
EP2074747B1 (en) 2006-09-28 2015-08-05 PacketFront Network Products AB Method for automatically providing a customer equipment with the correct service
DE112013006773T5 (de) 2013-03-06 2015-12-10 SiEVA Vorrichtung für high-side Transistor-Brückentreiber
US10752902B2 (en) * 2014-09-23 2020-08-25 Board Of Trustees Of Michigan State University Compositions comprising fusion proteins useful for modulating an immune response
EA201791806A1 (ru) * 2015-02-10 2017-12-29 Орегон Хелс Энд Сайенс Юниверсити Способы и композиции, полезные при генерировании неканонических cd8+ т-клеточных ответов
US10688164B2 (en) 2015-11-20 2020-06-23 Oregon Health & Science University CMV vectors comprising microRNA recognition elements
AU2017280065B2 (en) * 2016-06-22 2021-07-01 International Aids Vaccine Initiative, Inc. Recombinant cytomegalovirus vectors as vaccines for tuberculosis

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN110036112A (zh) * 2016-10-18 2019-07-19 俄勒冈健康与科学大学 引发受主要组织相容性复合体e分子限制的t细胞的巨细胞病毒载体

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CA3148642A1 (en) 2021-02-25
AU2020334061A1 (en) 2022-03-10
AU2020334061B2 (en) 2026-06-11
MX2022002154A (es) 2022-03-17
KR20220047619A (ko) 2022-04-18
CO2022002922A2 (es) 2022-04-19
WO2021034964A1 (en) 2021-02-25
JP2025131719A (ja) 2025-09-09
EP4017985A1 (en) 2022-06-29
EP4017985A4 (en) 2023-09-27
PH12022550439A1 (en) 2023-03-13
JP2022544704A (ja) 2022-10-20
BR112022003159A2 (pt) 2022-05-17
US20220307054A1 (en) 2022-09-29
IL290748A (en) 2022-04-01
CR20220093A (es) 2022-06-15
NZ785288A (en) 2025-09-26
MY210519A (en) 2025-09-29
JP7693651B2 (ja) 2025-06-17
ECSP22013145A (es) 2022-04-29
CN114402080A (zh) 2022-04-26
CL2022000398A1 (es) 2023-03-17
PE20220648A1 (es) 2022-04-28
DOP2022000041A (es) 2022-08-15

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