MX2022002154A - Modulacion de las respuestas de celulas t por ul18 del citomegalovirus humano. - Google Patents

Modulacion de las respuestas de celulas t por ul18 del citomegalovirus humano.

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Publication number
MX2022002154A
MX2022002154A MX2022002154A MX2022002154A MX2022002154A MX 2022002154 A MX2022002154 A MX 2022002154A MX 2022002154 A MX2022002154 A MX 2022002154A MX 2022002154 A MX2022002154 A MX 2022002154A MX 2022002154 A MX2022002154 A MX 2022002154A
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MX
Mexico
Prior art keywords
cell responses
human cytomegalovirus
modulation
mhc
methods
Prior art date
Application number
MX2022002154A
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English (en)
Inventor
Scott G Hansen
Daniel Malouli
Klaus J Frueh
Louis J Picker
Original Assignee
Univ Oregon Health & Science
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Publication date
Application filed by Univ Oregon Health & Science filed Critical Univ Oregon Health & Science
Publication of MX2022002154A publication Critical patent/MX2022002154A/es

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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Abstract

La revelación se refiere a métodos de modulación de respuestas de células T por UL18 de citomegalovirus humano. La revelación también se refiere a métodos para generar células T CD8+ restringidas por MHC-Ia, MHC-II y/o MHC-E.
MX2022002154A 2019-08-20 2020-08-19 Modulacion de las respuestas de celulas t por ul18 del citomegalovirus humano. MX2022002154A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962889310P 2019-08-20 2019-08-20
PCT/US2020/047050 WO2021034964A1 (en) 2019-08-20 2020-08-19 Modulation of t cell responses by ul18 of human cytomegalovirus

Publications (1)

Publication Number Publication Date
MX2022002154A true MX2022002154A (es) 2022-03-17

Family

ID=74660048

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MX2022002154A MX2022002154A (es) 2019-08-20 2020-08-19 Modulacion de las respuestas de celulas t por ul18 del citomegalovirus humano.

Country Status (17)

Country Link
US (1) US20220307054A1 (es)
EP (1) EP4017985A4 (es)
JP (1) JP2022544704A (es)
KR (1) KR20220047619A (es)
CN (1) CN114402080A (es)
AU (1) AU2020334061A1 (es)
BR (1) BR112022003159A2 (es)
CA (1) CA3148642A1 (es)
CL (1) CL2022000398A1 (es)
CO (1) CO2022002922A2 (es)
CR (1) CR20220093A (es)
DO (1) DOP2022000041A (es)
EC (1) ECSP22013145A (es)
IL (1) IL290748A (es)
MX (1) MX2022002154A (es)
PE (1) PE20220648A1 (es)
WO (1) WO2021034964A1 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023034801A1 (en) * 2021-08-31 2023-03-09 Vir Biotechnology, Inc. Recombinant hcmv vectors and uses thereof
WO2024059635A2 (en) * 2022-09-13 2024-03-21 Oregon Health And Science University Universal t cell-based, cmv-vectored vaccine for influenza

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1410314A (en) 1920-11-04 1922-03-21 Edgar B Hyatt Garage-door control
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US20020069244A1 (en) 1999-11-24 2002-06-06 John Blair Message delivery system billing method and apparatus
EP1364037A4 (en) * 2001-02-02 2005-08-03 Chemocentryx Inc METHODS AND COMPOSITIONS USEFUL IN STIMULATING AN IMMUNE RESPONSE
US8289976B2 (en) 2006-09-28 2012-10-16 Packetfront Network Products Ab Method for automatically providing a customer equipment with the correct service
DE112013006773T5 (de) 2013-03-06 2015-12-10 SiEVA Vorrichtung für high-side Transistor-Brückentreiber
WO2016049022A1 (en) * 2014-09-23 2016-03-31 Board Of Trustees Of Michigan State University Compositions and methods for modulating an immune response
EP3256595A4 (en) * 2015-02-10 2018-09-26 Oregon Health & Science University Methods and compositions useful in generating non canonical cd8+ t cell responses
CN116926128A (zh) 2015-11-20 2023-10-24 俄勒冈健康与科学大学 包含微小rna识别元件的cmv载体
WO2017223146A1 (en) * 2016-06-22 2017-12-28 Aeras Recombinant cytomegalovirus vectors as vaccines for tuberculosis
BR112019007982A2 (pt) 2016-10-18 2019-07-02 Univ Oregon Health & Science vetores de citomegalovírus elicitando células t restringidas por moléculas do complexo de histocompatibilidade e principal

Also Published As

Publication number Publication date
CO2022002922A2 (es) 2022-04-19
CA3148642A1 (en) 2021-02-25
EP4017985A4 (en) 2023-09-27
DOP2022000041A (es) 2022-08-15
PE20220648A1 (es) 2022-04-28
WO2021034964A1 (en) 2021-02-25
JP2022544704A (ja) 2022-10-20
IL290748A (en) 2022-04-01
CN114402080A (zh) 2022-04-26
CL2022000398A1 (es) 2023-03-17
KR20220047619A (ko) 2022-04-18
CR20220093A (es) 2022-06-15
US20220307054A1 (en) 2022-09-29
BR112022003159A2 (pt) 2022-05-17
ECSP22013145A (es) 2022-04-29
AU2020334061A1 (en) 2022-03-10
EP4017985A1 (en) 2022-06-29

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