CN114377108A - Oral liquid, sea cucumber and cordyceps peptide - Google Patents
Oral liquid, sea cucumber and cordyceps peptide Download PDFInfo
- Publication number
- CN114377108A CN114377108A CN202210081746.4A CN202210081746A CN114377108A CN 114377108 A CN114377108 A CN 114377108A CN 202210081746 A CN202210081746 A CN 202210081746A CN 114377108 A CN114377108 A CN 114377108A
- Authority
- CN
- China
- Prior art keywords
- percent
- sea cucumber
- cordyceps
- oral liquid
- peptide
- Prior art date
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Abstract
The invention relates to the technical field of health care products and discloses an oral liquid sea cucumber cordyceps peptide which is prepared from the following raw materials in percentage by weight: the sea cucumber polypeptide preparation comprises 25-35% of sea cucumber, 7-13% of medlar, 3-7% of beef kidney, 3-7% of ginseng, 3-7% of radix ophiopogonis, 0.5-2% of dried orange peel, 0.1-0.5% of xylo-oligosaccharide, 0.15-0.05% of sodium carboxymethyl cellulose, 00.15-0.05% of potassium sorbate, 0.1-0.3% of cordyceps sinensis and 40-60% of pure water.
Description
Technical Field
The invention belongs to the technical field of health care products, and particularly relates to an oral liquid, namely sea cucumber cordyceps peptide.
Background
Essence is an essence formed by fusion of life substances of innate parents and acquired food essence, is the origin of human life, is all useful life substances in the human body, is the most basic substance for forming and maintaining human life activities, and is the essence by the biological peptide.
It is kept secret and kept secret, and is yin-nourishing compared with qi's movement. Essence has the important function of life reproduction, and also has the functions of nourishing, transforming blood, regulating qi, and refreshing mind. Essence can moisten and nourish the viscera, body constituents, sense organs and orifices of the human body. The innate essence and acquired essence are abundant, so that the zang-fu organs and kidneys are also abundant, so that the zang-fu organs, organs and orifices of the whole body are nourished and various physiological functions can be performed normally. If innate essence deficiency or acquired essence is obstructed, the essence deficiency of zang-fu organs will lose its nourishing effect, and the viscera tissues and orifices will not be nourished or supported by essence, and the function will fail to be performed normally, even decline. If kidney essence is damaged, growth and development are retarded or premature senility is observed.
The more enzymes in a human body are, the more complete the enzyme is, the healthier the life is, when no active enzyme exists in a human body, the life is finished, most of human diseases are related to enzyme deficiency or synthesis obstacle, the biological enzymolysis technology can enable a substance extract to be rich in active enzyme and promote metabolism of the human body, but the existing sea cucumber peptide is easy to extract and difficult to preserve activity, and therefore the oral liquid sea cucumber cordyceps peptide is provided.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides an oral liquid sea cucumber cordyceps peptide.
In order to achieve the purpose, the invention provides the following technical scheme:
an oral liquid sea cucumber cordyceps peptide is composed of the following raw materials in percentage by weight: comprises 25 to 35 percent of sea cucumber, 7 to 13 percent of medlar, 3 to 7 percent of cowberry kidney, 3 to 7 percent of ginseng, 3 to 7 percent of dwarf lilyturf tuber, 0.5 to 2 percent of dried orange peel, 0.1 to 0.5 percent of xylo-oligosaccharide, 0.15 to 0.05 percent of sodium carboxymethyl cellulose, 00.15 to 0.05 percent of potassium sorbate, 0.1 to 0.3 percent of cordyceps sinensis and 40 to 60 percent of pure water.
The production of the oral liquid, namely the sea cucumber cordyceps peptide comprises the following steps;
s1: preparing raw materials: selecting 25-35% of sea cucumber, 7-13% of medlar, 3-7% of beef kidney, 3-7% of ginseng, 3-7% of dwarf lilyturf tuber, 0.5-2% of dried orange peel, 0.1-0.5% of xylo-oligosaccharide, 0.1-0.5% of sodium carboxymethyl cellulose, 0.1-0.5% of potassium sorbate, 0.1-0.3% of cordyceps sinensis and 40-60% of pure water for prefabrication.
S2: enzymolysis of sea cucumber peptide; soaking fresh sea cucumber in clear water for 12-24h, wherein the clear water needs to be replaced for 3-5 times in the sea cucumber soaking process, after the sea cucumber soaking process is finished, high-pressure cooking is carried out, the sea cucumber and pure water are placed in a high-pressure cooker, the temperature of the high-pressure cooker is 130-, adding 17% of active carbon of dry matter weight for removing odor after enzymolysis, adding NaOH to adjust pH to 6.0-7.0, heating, inactivating enzyme, sterilizing, cooling to 70-75 deg.C, standing for 4 hr, adding Cordyceps to obtain sea cucumber peptide, and freezing at ultralow temperature to break cell wall;
s3: processing medicinal materials, namely respectively placing the ox kidney, the dried orange peel, the ginseng and the dwarf lilyturf tuber in a crushing device for crushing, placing the human participation dwarf lilyturf tuber in an earthenware pot after crushing, soaking the ginseng and the dwarf lilyturf tuber in the earthenware pot for 10-20min, simultaneously placing the ox kidney in the earthenware pot after pre-rinsing, heating the earthenware pot after the ox kidney is immersed in water at the heating temperature of 100 ℃ and 120 ℃ for 0.5-1.5h, placing the Chinese wolfberry in the earthenware pot after heating to 0.5h, obtaining Chinese medicinal liquid after heating the ox kidney, the ginseng, the dwarf lilyturf tuber and the Chinese wolfberry to obtain Chinese medicinal liquid, placing the Chinese medicinal liquid in the earthenware pot in a distillation device, processing the Chinese medicinal liquid in the distillation device, collecting the Chinese medicinal liquid in the ware pot after distillation processing, placing the collected Chinese medicinal liquid in a pressure cooker for high-pressure extraction work, the concentration and the drug property of the traditional Chinese medicine liquid are improved;
s4: and (3) filling the oral liquid, namely filling the medicinal materials, namely putting the concentrated Chinese medicinal liquid in the S3, the xylo-oligosaccharide, the sodium carboxymethyl cellulose and the potassium sorbate in the S1, the sea cucumber peptide in the S2 and the concentrated Chinese medicinal liquid in the S3 into a filling machine, and mixing the raw materials through the mixing in the filling machine to finish the filling work of the raw materials to obtain the oral liquid.
Preferably, the sea cucumber in the S1 is fresh sea cucumber, and when the sea cucumber is used, the sea cucumber needs to spit sand in clear water, so that the quality and the drug property of the oral liquid are prevented from being influenced in the processing process.
Preferably, the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 33 percent of sea cucumber, 7 percent of medlar, 3 percent of ox kidney, 7 percent of ginseng, 3 percent of dwarf lilyturf tuber, 2 percent of tangerine peel, 0.5 percent of xylo-oligosaccharide, 0.05 percent of sodium carboxymethyl cellulose, 0.05 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 43.2 percent of pure water.
Preferably, the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 35% of sea cucumber, 7% of medlar, 3% of ox kidney, 3% of ginseng, 3% of dwarf lilyturf tuber, 2% of dried orange peel, 0.3% of xylo-oligosaccharide, 0.15% of sodium carboxymethyl cellulose, 0.15% of potassium sorbate, 0.2% of cordyceps sinensis and 46.2% of pure water.
Preferably, the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 30% of sea cucumber, 10% of medlar, 5% of ox kidney, 5% of ginseng, 5% of dwarf lilyturf tuber, 1% of dried orange peel, 0.3% of xylo-oligosaccharide, 0.1% of sodium carboxymethyl cellulose, 0.1% of potassium sorbate, 0.2% of cordyceps sinensis and 43.3% of pure water.
Preferably, the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 25 percent of sea cucumber, 13 percent of medlar, 6 percent of ox kidney, 7 percent of ginseng, 7 percent of dwarf lilyturf tuber, 0.5 percent of tangerine peel, 0.5 percent of xylo-oligosaccharide, 0.1 percent of sodium carboxymethyl cellulose, 0.1 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 40.6 percent of pure water.
Compared with the prior art, the invention provides the oral liquid sea cucumber cordyceps peptide, which has the following beneficial effects:
1. the traditional Chinese medicine formula of the invention has the effects of supplementing qi and nourishing yin, is supported by the traditional Chinese medicine liquid, can well preserve the activity of the sea cucumber peptide, can be absorbed within one minute on an empty stomach, can directly absorb the sea cucumber peptide without digestion, and can tonify the kidney, provide high-quality protein which is higher in quality and easier to absorb for a human body, and in order to more reasonably and effectively utilize the components of the medicinal materials, the sea cucumber peptide of the formula is processed and produced by adopting a biological enzymolysis technology, and other medicinal materials are processed and produced by adopting a multi-stage separation and high-pressure extraction technology, and according to different parts and properties of the related medicinal materials, three extraction processes of conventional decoction, distillation separation and high-pressure extraction are respectively adopted to obtain 4 kinds of extracts, and finally the extracts are synthesized;
2. the formula of the formula after compatibility is clear in major and minor, has a clean and reasonable structure, has the effects of tonifying kidney, replenishing vital essence and resisting aging by reusing the sea cucumber, the medlar and the ox kidney extract, and has the advantages of respective emphasis, so that the whole formula mainly replenishes essence, has the effects of nourishing yin and blood, and tonifying but not greasy, and is free of deficiency; the ginseng and the dwarf lilyturf tuber have the effects of supplementing qi and nourishing yin, and provide nutrient substances which are particularly urgently needed by a human body; the dried orange peel can regulate qi, invigorate spleen and govern spleen transportation and transformation, so that the formula essences are better absorbed, and the dried orange peel can quickly tonify kidney and replenish essence: the radix ophiopogonis can timely supplement water to the skin which is short of body fluid (commonly called water), and delay aging, and the formula is safe and effective and can be completely used as a daily health-care beverage;
3. the product has the core effects of tonifying qi and blood, tonifying kidney and replenishing essence, and is tried by more than 100 volunteers, one adverse reaction does not occur, the regular tracking and feedback after the product is taken, the sleep quality is improved, the immunity is enhanced, the complexion is ruddy and glossy, and the like.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
In the drawings:
FIG. 1 is a production flow chart of the oral liquid sea cucumber cordyceps peptide provided by the invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments; all other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
referring to fig. 1, an oral liquid of sea cucumber cordyceps peptide is composed of the following raw materials by weight: comprises 33 percent of sea cucumber, 7 percent of medlar, 3 percent of ox kidney, 7 percent of ginseng, 3 percent of dwarf lilyturf tuber, 2 percent of tangerine peel, 0.5 percent of xylo-oligosaccharide, 0.05 percent of sodium carboxymethyl cellulose, 0.05 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 43.4 percent of pure water.
The production of the oral liquid, namely the sea cucumber cordyceps peptide, comprises the following steps;
s1: preparing raw materials: selecting 33% of sea cucumber, 7% of medlar, 3% of ox kidney, 7% of ginseng, 3% of dwarf lilyturf tuber, 2% of dried orange peel, 0.5% of xylo-oligosaccharide, 0.05% of sodium carboxymethyl cellulose, 0.05% of potassium sorbate, 0.2% of cordyceps sinensis and 43.4% of pure water for prefabrication.
S2: enzymolysis of sea cucumber peptide; soaking fresh sea cucumbers in clean water for 12 hours, wherein the clean water needs to be replaced for 3 times in the sea cucumber soaking process, after the sea cucumbers are soaked, high-pressure cooking is carried out, the sea cucumbers and pure water are placed in a high-pressure pot, the temperature of the high-pressure pot is 1150 ℃, the cooking time of the high-pressure pot is 1.5 hours, the sea cucumber extracting solution is filtered and then placed in a cooling tank for cooling, after the sea cucumber cooling solution is cooled, soluble compound protease is added for enzymolysis, the enzymolysis condition is pH8.0, the temperature is 40 ℃, the time is 5 hours, after the enzymolysis is finished, active carbon with 17 percent of the weight of dry matter is added for deodorization, then NaOH is added for regulating the pH value to be 6.0, after the temperature is raised, the enzyme is inactivated and the sterilization is carried out, the temperature is reduced to 75 ℃, the standing is carried out for 4 hours, cordyceps sinensis is added to obtain sea cucumber peptides, and the cordyceps sinensis is subjected to wall breaking by using an ultralow temperature freezing technology;
s3: processing the raw materials, respectively placing ren bovis Seu Bubali, pericarpium Citri Tangerinae, Ginseng radix and radix Ophiopogonis in a pulverizing device, pulverizing, placing radix Ginseng and radix Ophiopogonis in a casserole, soaking Ginseng radix and radix Ophiopogonis in cold water for 20min, meanwhile, the ox kidney is placed in the earthen pot after being pre-watered, the ox kidney is heated after being watered, the heating temperature is 120 ℃, the heating time is 1h, the medlar is placed in the earthen pot after being heated to 0.5h, the ox kidney, the ginseng, the dwarf lilyturf tuber and the medlar are heated to obtain the traditional Chinese medicine liquid, the traditional Chinese medicine liquid in the earthen pot is placed in a distillation device, processing the Chinese medicinal liquid by distillation device, collecting the Chinese medicinal liquid in the casserole after distillation, placing the collected Chinese medicinal liquid in a pressure cooker, the traditional Chinese medicine liquid in the casserole is extracted under high pressure by a pressure cooker, so that the concentration and the drug property of the traditional Chinese medicine liquid are improved;
s4: and (3) filling the oral liquid, namely filling the medicinal materials, namely putting the concentrated Chinese medicinal liquid in the S3, the xylo-oligosaccharide, the sodium carboxymethyl cellulose and the potassium sorbate in the S1, the sea cucumber peptide in the S2 and the concentrated Chinese medicinal liquid in the S3 into a filling machine, and mixing the raw materials through the mixing in the filling machine to finish the filling work of the raw materials to obtain the oral liquid.
S1, the sea cucumber is fresh and needs to be spitted in clear water when in use, so that the quality and the drug property of the oral liquid are prevented from being influenced in the processing process.
Example 2:
referring to fig. 1, an oral liquid of sea cucumber cordyceps peptide is composed of the following raw materials by weight: 35% of sea cucumber, 7% of medlar, 3% of ox kidney, 3% of ginseng, 3% of dwarf lilyturf tuber, 2% of dried orange peel, 0.3% of xylo-oligosaccharide, 0.15% of sodium carboxymethyl cellulose, 0.15% of potassium sorbate, 0.2% of cordyceps sinensis and 46.4% of pure water.
The production of the oral liquid, namely the sea cucumber cordyceps peptide, comprises the following steps;
s1: preparing raw materials: the preparation method comprises the steps of selecting 35% of sea cucumber, 7% of medlar, 3% of beef kidney, 3% of ginseng, 3% of radix ophiopogonis, 2% of dried orange peel, 0.3% of xylo-oligosaccharide, 0.15% of sodium carboxymethyl cellulose, 0.15% of potassium sorbate, 0.2% of cordyceps sinensis and 46.4% of pure water for prefabrication.
S2: enzymolysis of sea cucumber peptide; soaking fresh sea cucumbers in clean water for 24 hours, wherein the clean water needs to be replaced for 5 times in the sea cucumber soaking process, after the sea cucumbers are soaked, high-pressure cooking is carried out, the sea cucumbers and pure water are placed in a pressure cooker, the temperature of the pressure cooker is 150 ℃, the cooking time of the pressure cooker is 2 hours, the sea cucumber extracting solution is filtered and then placed in a cooling tank for cooling, after the sea cucumber cooling liquid is cooled, soluble compound protease is added for enzymolysis, the enzymolysis condition is pH9.0, the temperature is 40 ℃, the time is 5 hours, after the enzymolysis is finished, active carbon accounting for 17 percent of the weight of dry matter is added for deodorization, then NaOH is added for regulating the pH value to-7.0, after the temperature is raised, enzyme is inactivated and sterilized, the temperature is reduced to 75 ℃, standing is carried out for 4 hours, cordyceps sinensis is added to obtain sea cucumber peptides, and the cordyceps sinensis uses an ultralow temperature freezing wall breaking technology;
s3: processing the raw materials, respectively placing ren bovis Seu Bubali, pericarpium Citri Tangerinae, Ginseng radix and radix Ophiopogonis in a pulverizing device, pulverizing, placing radix Ginseng and radix Ophiopogonis in a casserole, soaking Ginseng radix and radix Ophiopogonis in cold water for 15min, meanwhile, the ox kidney is placed in the earthen pot after being pre-watered, the ox kidney is heated after being watered, the heating temperature is 110 ℃, the heating time is 1.5h, the medlar is placed in the earthen pot after being heated to 0.5h, the ox kidney, the ginseng, the radix ophiopogonis and the medlar are heated to obtain the traditional Chinese medicine liquid, the traditional Chinese medicine liquid in the earthen pot is placed in a distillation device, processing the Chinese medicinal liquid by distillation device, collecting the Chinese medicinal liquid in the casserole after distillation, placing the collected Chinese medicinal liquid in a pressure cooker, the traditional Chinese medicine liquid in the casserole is extracted under high pressure by a pressure cooker, so that the concentration and the drug property of the traditional Chinese medicine liquid are improved;
s4: and (3) filling the oral liquid, namely filling the medicinal materials, namely putting the concentrated Chinese medicinal liquid in the S3, the xylo-oligosaccharide, the sodium carboxymethyl cellulose and the potassium sorbate in the S1, the sea cucumber peptide in the S2 and the concentrated Chinese medicinal liquid in the S3 into a filling machine, and mixing the raw materials through the mixing in the filling machine to finish the filling work of the raw materials to obtain the oral liquid.
S1, the sea cucumber is fresh and needs to be spitted in clear water when in use, so that the quality and the drug property of the oral liquid are prevented from being influenced in the processing process.
Example 3:
referring to fig. 1, an oral liquid of sea cucumber cordyceps peptide is composed of the following raw materials by weight: comprises 30 percent of sea cucumber, 10 percent of medlar, 5 percent of ox kidney, 5 percent of ginseng, 5 percent of dwarf lilyturf tuber, 1 percent of dried orange peel, 0.3 percent of xylo-oligosaccharide, 0.1 percent of sodium carboxymethyl cellulose, 0.1 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 43.5 percent of pure water.
The production of the oral liquid, namely the sea cucumber cordyceps peptide, comprises the following steps;
s1: preparing raw materials: 30 percent of sea cucumber, 10 percent of medlar, 5 percent of ox kidney, 5 percent of ginseng, 5 percent of dwarf lilyturf tuber, 1 percent of tangerine peel, 0.3 percent of xylo-oligosaccharide, 0.1 percent of sodium carboxymethyl cellulose, 0.1 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 43.5 percent of pure water are selected for prefabrication.
S2: enzymolysis of sea cucumber peptide; soaking fresh sea cucumbers in clear water for 18 hours, wherein the clear water needs to be replaced 4 times in the sea cucumber soaking process, after the sea cucumbers are soaked, high-pressure cooking is carried out, the sea cucumbers and pure water are placed in a high-pressure pot, the temperature of the high-pressure pot is 140 ℃, the cooking time of the high-pressure pot is 2 hours, the sea cucumber extracting solution is filtered and then placed in a cooling tank for cooling, after the sea cucumber cooling liquid is cooled, soluble compound protease is added for enzymolysis, the enzymolysis condition is pH8.5, the temperature is 35 ℃, the time is 4 hours, after the enzymolysis is finished, active carbon accounting for 17 percent of the weight of dry matter is added for deodorization, then NaOH is added for regulating the pH to be 6.5, after the temperature is raised, enzyme is inactivated and sterilized, the temperature is reduced to 75 ℃, standing is carried out for 4 hours, cordyceps sinensis is added to obtain sea cucumber peptides, and the cordyceps sinensis uses an ultralow temperature freezing wall breaking technology;
s3: processing the raw materials, respectively placing ren bovis Seu Bubali, pericarpium Citri Tangerinae, Ginseng radix and radix Ophiopogonis in a pulverizing device, pulverizing, placing radix Ginseng and radix Ophiopogonis in a casserole, soaking Ginseng radix and radix Ophiopogonis in cold water for 15min, meanwhile, the ox kidney is placed in the earthen pot after being pre-watered, the ox kidney is heated after being watered, the heating temperature is 110 ℃, the heating time is 1.5h, the medlar is placed in the earthen pot after being heated to 0.5h, the ox kidney, the ginseng, the radix ophiopogonis and the medlar are heated to obtain the traditional Chinese medicine liquid, the traditional Chinese medicine liquid in the earthen pot is placed in a distillation device, processing the Chinese medicinal liquid by distillation device, collecting the Chinese medicinal liquid in the casserole after distillation, placing the collected Chinese medicinal liquid in a pressure cooker, the traditional Chinese medicine liquid in the casserole is extracted under high pressure by a pressure cooker, so that the concentration and the drug property of the traditional Chinese medicine liquid are improved;
s4: and (3) filling the oral liquid, namely filling the medicinal materials, namely putting the concentrated Chinese medicinal liquid in the S3, the xylo-oligosaccharide, the sodium carboxymethyl cellulose and the potassium sorbate in the S1, the sea cucumber peptide in the S2 and the concentrated Chinese medicinal liquid in the S3 into a filling machine, and mixing the raw materials through the mixing in the filling machine to finish the filling work of the raw materials to obtain the oral liquid.
S1, the sea cucumber is fresh and needs to be spitted in clear water when in use, so that the quality and the drug property of the oral liquid are prevented from being influenced in the processing process.
Example 4:
referring to fig. 1, an oral liquid of sea cucumber cordyceps peptide is composed of the following raw materials by weight: 25 percent of sea cucumber, 13 percent of medlar, 6 percent of ox kidney, 7 percent of ginseng, 7 percent of dwarf lilyturf tuber, 0.5 percent of tangerine peel, 0.5 percent of xylo-oligosaccharide, 0.1 percent of sodium carboxymethyl cellulose, 0.1 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 40.8 percent of pure water.
The production of the oral liquid, namely the sea cucumber cordyceps peptide, comprises the following steps;
s1: preparing raw materials: 25 percent of sea cucumber, 13 percent of medlar, 6 percent of ox kidney, 7 percent of ginseng, 7 percent of dwarf lilyturf tuber, 0.5 percent of tangerine peel, 0.5 percent of xylo-oligosaccharide, 0.1 percent of sodium carboxymethyl cellulose, 0.1 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 40.8 percent of pure water are selected for prefabrication.
S2: enzymolysis of sea cucumber peptide; soaking fresh sea cucumbers in clear water for 4 hours, wherein the clear water needs to be replaced for 5 times in the sea cucumber soaking process, after the sea cucumbers are soaked, high-pressure cooking is carried out, the sea cucumbers and pure water are placed in a pressure cooker, the temperature of the pressure cooker is 150 ℃, the cooking time of the pressure cooker is 2.5 hours, the sea cucumber extracting solution is filtered and then placed in a cooling tank for cooling, after the sea cucumber cooling solution is cooled, soluble compound protease is added for enzymolysis, the enzymolysis condition is pH8.7, the temperature is 34 ℃, the time is 3 hours, after the enzymolysis is finished, active carbon accounting for 17 percent of the weight of dry matter is added for deodorization, then NaOH is added for regulating the pH to be 6.7, after the temperature is raised, enzyme is inactivated and sterilized, the temperature is reduced to 72 ℃, standing is carried out for 4 hours, cordyceps sinensis is added to obtain sea cucumber peptides, and the cordyceps sinensis is subjected to wall breaking by using an ultralow temperature freezing technology;
s3: processing the raw materials, respectively placing ren bovis Seu Bubali, pericarpium Citri Tangerinae, Ginseng radix and radix Ophiopogonis in a pulverizing device, pulverizing, placing radix Ginseng and radix Ophiopogonis in a casserole, soaking Ginseng radix and radix Ophiopogonis in cold water for 15min, meanwhile, the ox kidney is placed in the earthen pot after being pre-watered, the ox kidney is heated after being watered, the heating temperature is 110 ℃, the heating time is 1.2h, the medlar is placed in the earthen pot after being heated to 0.5h, the ox kidney, the ginseng, the radix ophiopogonis and the medlar are heated to obtain the traditional Chinese medicine liquid, the traditional Chinese medicine liquid in the earthen pot is placed in a distillation device, processing the Chinese medicinal liquid by distillation device, collecting the Chinese medicinal liquid in the casserole after distillation, placing the collected Chinese medicinal liquid in a pressure cooker, the traditional Chinese medicine liquid in the casserole is extracted under high pressure by a pressure cooker, so that the concentration and the drug property of the traditional Chinese medicine liquid are improved;
s4: and (3) filling the oral liquid, namely filling the medicinal materials, namely putting the concentrated Chinese medicinal liquid in the S3, the xylo-oligosaccharide, the sodium carboxymethyl cellulose and the potassium sorbate in the S1, the sea cucumber peptide in the S2 and the concentrated Chinese medicinal liquid in the S3 into a filling machine, and mixing the raw materials through the mixing in the filling machine to finish the filling work of the raw materials to obtain the oral liquid.
S1, the sea cucumber is fresh and needs to be spitted in clear water when in use, so that the quality and the drug property of the oral liquid are prevented from being influenced in the processing process.
Clinical effects and observations
In four groups of embodiments of the invention, the oral liquid produced in the embodiment 3 has the highest quality, the drug effect is most suitable for users, the core effects of the formula product are tonifying qi and enriching blood, tonifying kidney and replenishing essence, the formula product is tried by more than 100 volunteers, no adverse reaction occurs, regular tracking feedback is carried out after taking, the sleep quality is improved, the immunity is enhanced, the complexion is ruddy and glossy, and the like.
Suitable for people and application
The peptide is an important substance for forming all cells and tissues of a human body, is warm, moist, nourishing and nutrient-supplementing from inside to outside, and is suitable for various crowds:
1. middle aged and elderly people group
2. People with weak body
3. Working group with high pressure and tired
4. Postoperative physical weakness
5. Pregnant and postpartum recovery population
6. Brain population for students at school
7. Children growth crowd
8. People with gastrointestinal discomfort
9. Sub-health office worker
The use method comprises the following steps: heating for 5min (water temperature can not exceed 70 deg.C), taking orally with open web, 15-25 ml each time, 1-3 times per day, and can be absorbed within one minute without digestion, and can directly absorb blood and kidney without digestion, thereby providing high quality protein with high quality and easy absorption for human body.
In order to more reasonably and effectively utilize the components of the medicinal materials, the sea cucumber peptide of the formula is processed and produced by adopting a biological enzymolysis technology and adopting a multi-stage separation and high-pressure extraction technology for other medicinal materials, three extraction processes of conventional decoction, distillation separation and high-pressure extraction are respectively adopted according to different parts and properties of the related medicinal materials to obtain 4 kinds of extracts, and finally the extracts are synthesized,
the biological enzymolysis technology is characterized in that a corresponding enzyme (usually hydrolase) is selected to decompose biomacromolecules in a polymer form into micromolecular proteins or polypeptides by utilizing the characteristic of high specificity of enzymatic reaction catalyzed by the biological enzyme, the biological enzymolysis technology has the advantages that substances are decomposed by the catalysis of the enzyme, the capability of enzymatic chemical reaction is called enzyme activity (or called enzyme activity), the enzyme activity can be regulated and controlled by various factors, so that an organism can adapt to the change of external conditions to maintain the life activity, the characteristics of different active ingredients of the substances are mastered by utilizing different catalysis of different enzymes, the active substances of the substances can be extracted, the traditional substance extraction adopts high-temperature continuous decomposition or low-temperature quick freezing, so that most of the active substances of the substances are destroyed, the activity of an extract is lost, the exertion of the efficacy is influenced, and the organism is composed of cells, each cell shows various life activities due to the existence of enzyme, the metabolism in vivo can be carried out, the enzyme is a catalyst of the metabolism in the human body, various biochemical reactions can be carried out in the human body only when the enzyme exists, the more the enzyme exists in the human body, the more complete the enzyme exists, the healthier the life is, when the active enzyme does not exist in the human body, the life is ended, and most of human diseases are related to enzyme deficiency or synthesis obstacle.
Sea cucumber is the first acknowledged 'eight delicacies in sea', is a big dish pressed on a high-grade banquet, is also an important tonic for health preservation and nourishing in traditional Chinese medicine, is a seafood which is rarely high in protein, low in fat and free of cholesterol on the earth, contains high-quality protein, rich vitamins and minerals and more than 60 nutrient substances needed by a human body, contains more than 50 and can be named as a natural nutrition treasure house, and the most precious part of the sea cucumber is a special non-nutrient substance-rare active substance contained in other bodies besides rich nutrition.
1. Sea cucumber autolytic enzyme
The sea cucumber autolytic enzyme is named as 'sea gold', and is an extremely precious substance which is not possessed by any other organisms. Practice proves that the sea cucumber autolytic enzyme can prevent and inhibit the formation of human thrombus, has obvious effect on the recovery of patients with coronary heart disease, myocardial infarction and cerebral thrombosis, and prevents and reduces the occurrence of cardiovascular and cerebrovascular diseases.
2. Sea cucumber acidic mucopolysaccharide
The sea cucumber acidic mucopolysaccharide is called 'gold in sea', is a high-efficiency immunomodulator, has a broad-spectrum anticancer effect, and is proved by medical researches: the sea cucumber acidic mucopolysaccharide has obvious curative effect on diabetic patients, can effectively reduce blood sugar and urine sugar, and can effectively inhibit the occurrence of diabetic complications.
3. Sea cucumber saponins
The sea cucumber contains a large amount of holothurin toxins in the viscera, body wall and glands, the toxins are also called holothurin, have obvious functions of promoting blood circulation and removing blood stasis, can reduce platelet coagulation, prevent the formation of venous embolism, and have obvious improvement effects on cerebral thrombosis, myocardial infarction recovery period and ischemic heart disease.
4. Chondroitin sulfate
Chondroitin sulfate is a substance required by construction and repair of human cartilage tissues, has a good promoting effect on generation of bones, ligaments and joint fluid, has a function of reconstructing damaged and aged soft tissues, can prevent cartilage abrasion, and has an obvious improving effect on senile arthritis and joint rheumatism.
5. Chitosan
Is the only animal cellulose with positive charges, positive ions and weak alkalinity in the universe. Regulating acid-base balance of human body, has strong functions of activating, repairing and regenerating cells, and can carry harmful substances and heavy metals away; improving the absorption of inorganic salts such as calcium, and improving the immunity of the organism.
6. Collagen protein
Is an important component in extracellular matrix, and the stichopus japonicus collagen can be compared with donkey-hide gelatin, tortoise-plastron glue, antler glue and the like in the traditional Chinese medicine on the components and the effects. Has good effects of promoting hematogenesis, nourishing blood and promoting calcium absorption; resisting tumor, eliminating inflammation, and improving immunity; maintaining beauty, keeping young, and restoring and enhancing skin elasticity.
SOD (superoxide dismutase)
Is an active substance originated from life, and can eliminate harmful substances generated in the metabolism process of human body; eliminating excessive free radicals, regulating immunity, delaying aging, regulating female physiological cycle, and postponing climacteric period.
8. Xanthophyll
Is a flavonoid substance, and is orange red. The vitamin can not be synthesized by human body like some essential vitamins, can effectively remove and inhibit eye free radicals, and has good effects of protecting eyes and restoring vision.
9. Specific amino acids
Taurine: taurine is a special amino acid essential for human body, and has effects of promoting the development of important organs such as brain (especially the development of infant brain), protecting liver and promoting bile flow.
(ii) arginine: also belongs to conditionally essential amino acids, the sea cucumber contains very rich arginine, called arginine "radix Rubi Parvifolii", which is the main raw material of spermatid and has important effects on repairing tissue injury and stress!
Wolfberry fruit: sweet, flat, boxthorn leaf: bitter and sweet, cool in nature, and functional: wolfberry fruit: nourishing liver, nourishing kidney, moistening lung, tonifying deficiency, replenishing vital essence, clearing heat and improving eyesight.
The beef kidney: has the effects of tonifying kidney, replenishing vital essence, strengthening waist and knee joints and relieving arthralgia, and is commonly used for consumptive disease and kidney deficiency, impotence, qi deficiency, soreness and weakness of waist and knees and damp arthralgia.
Ginseng: sweet and slightly bitter in taste, warm and mild in nature. It enters spleen, lung and heart meridians. Invigorating qi, relieving depletion, promoting fluid production, tranquilizing mind, improving intelligence, invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, and tranquilizing mind.
Radix ophiopogonis: nourish yin and generate fluid, moisten lung and relieve cough, it is indicated for scanty fluid and thirst due to yin deficiency of lung and stomach, cough and hemoptysis, palpitation due to heart yin deficiency, easy fright and body fluid impairment due to heat in later stage of fever, etc., and it is combined with Sha Shen and Chuan Bei to treat dryness due to lung yin deficiency.
And (3) xylo-oligosaccharide: the health-care product has the advantages of reducing the production of toxic fermentation products and harmful bacterial enzymes, inhibiting pathogenic bacteria and diarrhea, preventing constipation, protecting liver function, reducing serum cholesterol, reducing blood pressure, enhancing immunity of the organism, resisting cancer, having good compatibility, promoting the organism to generate various nutrient substances including vitamin B1, B2, B6, B12, nicotinic acid and folic acid, preventing and protecting dental caries and inhibiting the breeding of oral bacteria.
Sodium carboxymethyl cellulose: the cellulose derivative has a glucose polymerization degree of 100-2000, a relative molecular mass of 242.16, and is white fibrous or granular powder, odorless, tasteless, hygroscopic, and insoluble in organic solvents.
The potassium sorbate is colorless to white scale-shaped crystal or crystalline powder, has no smell or slight smell, is mainly used as a food preservative with a molecular structure, belongs to an acid preservative matched with organic acid to improve the preservative reaction effect, and is prepared by taking potassium carbonate or potassium hydroxide and sorbic acid as raw materials.
Pure water: the method refers to that water subjected to distillation and condensation operations is distilled twice, namely redistilled water, and is distilled three times, so that new impurities are not introduced.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (7)
1. An oral liquid sea cucumber cordyceps peptide is characterized in that: the oral liquid sea cucumber cordyceps peptide is prepared from the following raw materials in percentage by weight: comprises 25 to 35 percent of sea cucumber, 7 to 13 percent of medlar, 3 to 7 percent of cowberry kidney, 3 to 7 percent of ginseng, 3 to 7 percent of dwarf lilyturf tuber, 0.5 to 2 percent of dried orange peel, 0.1 to 0.5 percent of xylo-oligosaccharide, 0.15 to 0.05 percent of sodium carboxymethyl cellulose, 00.15 to 0.05 percent of potassium sorbate, 0.1 to 0.3 percent of cordyceps sinensis and 40 to 60 percent of pure water.
2. The oral liquid sea cucumber cordyceps peptide according to claim 1, which is characterized in that: the production of the oral liquid, namely the sea cucumber cordyceps peptide comprises the following steps; 0.2 percent of cordyceps sinensis,
s1: preparing raw materials: selecting 25-35% of sea cucumber, 7-13% of medlar, 3-7% of beef kidney, 3-7% of ginseng, 3-7% of dwarf lilyturf tuber, 0.5-2% of dried orange peel, 0.1-0.5% of xylo-oligosaccharide, 0.1-0.5% of sodium carboxymethyl cellulose, 0.1-0.5% of potassium sorbate, 0.1-0.3% of cordyceps sinensis and 40-60% of pure water for prefabrication.
S2: enzymolysis of sea cucumber peptide; soaking fresh sea cucumber in clear water for 12-24h, wherein the clear water needs to be replaced for 3-5 times in the sea cucumber soaking process, after the sea cucumber soaking process is finished, high-pressure cooking is carried out, the sea cucumber and pure water are placed in a high-pressure cooker, the temperature of the high-pressure cooker is 130-, adding 17% of active carbon of dry matter weight for removing odor after enzymolysis, adding NaOH to adjust pH to 6.0-7.0, heating, inactivating enzyme, sterilizing, cooling to 70-75 deg.C, standing for 4 hr, adding Cordyceps to obtain sea cucumber peptide, and freezing at ultralow temperature to break cell wall;
s3: processing medicinal materials, namely respectively placing the ox kidney, the dried orange peel, the ginseng and the dwarf lilyturf tuber in a crushing device for crushing, placing the human participation dwarf lilyturf tuber in an earthenware pot after crushing, soaking the ginseng and the dwarf lilyturf tuber in the earthenware pot for 10-20min, simultaneously placing the ox kidney in the earthenware pot after pre-rinsing, heating the earthenware pot after the ox kidney is immersed in water at the heating temperature of 100 ℃ and 120 ℃ for 0.5-1.5h, placing the Chinese wolfberry in the earthenware pot after heating to 0.5h, obtaining Chinese medicinal liquid after heating the ox kidney, the ginseng, the dwarf lilyturf tuber and the Chinese wolfberry to obtain Chinese medicinal liquid, placing the Chinese medicinal liquid in the earthenware pot in a distillation device, processing the Chinese medicinal liquid in the distillation device, collecting the Chinese medicinal liquid in the ware pot after distillation processing, placing the collected Chinese medicinal liquid in a pressure cooker for high-pressure extraction work, the concentration and the drug property of the traditional Chinese medicine liquid are improved;
s4: and (3) filling the oral liquid, namely filling the medicinal materials, namely putting the concentrated Chinese medicinal liquid in the S3, the xylo-oligosaccharide, the sodium carboxymethyl cellulose and the potassium sorbate in the S1, the sea cucumber peptide in the S2 and the concentrated Chinese medicinal liquid in the S3 into a filling machine, and mixing the raw materials through the mixing in the filling machine to finish the filling work of the raw materials to obtain the oral liquid.
3. The oral liquid sea cucumber cordyceps peptide according to claim 1, which is characterized in that: s1, the sea cucumber is fresh and needs to be spitted in clear water when in use, so that the quality and the drug property of the oral liquid are prevented from being influenced in the processing process.
4. The oral liquid sea cucumber cordyceps peptide according to claim 1, which is characterized in that: the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 33 percent of sea cucumber, 7 percent of medlar, 3 percent of ox kidney, 7 percent of ginseng, 3 percent of dwarf lilyturf tuber, 2 percent of tangerine peel, 0.5 percent of xylo-oligosaccharide, 0.05 percent of sodium carboxymethyl cellulose, 0.05 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 43.2 percent of pure water.
5. The oral liquid sea cucumber cordyceps peptide according to claim 1, which is characterized in that: the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 35% of sea cucumber, 7% of medlar, 3% of ox kidney, 3% of ginseng, 3% of dwarf lilyturf tuber, 2% of dried orange peel, 0.3% of xylo-oligosaccharide, 0.15% of sodium carboxymethyl cellulose, 0.15% of potassium sorbate, 0.2% of cordyceps sinensis and 46.2% of pure water.
6. The oral liquid sea cucumber cordyceps peptide according to claim 1, which is characterized in that: the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 30% of sea cucumber, 10% of medlar, 5% of ox kidney, 5% of ginseng, 5% of dwarf lilyturf tuber, 1% of dried orange peel, 0.3% of xylo-oligosaccharide, 0.1% of sodium carboxymethyl cellulose, 0.1% of potassium sorbate, 0.2% of cordyceps sinensis and 43.3% of pure water.
7. The oral liquid sea cucumber cordyceps peptide according to claim 1, which is characterized in that: the oral liquid sea cucumber cordyceps peptide consists of the following components in percentage by weight: 25 percent of sea cucumber, 13 percent of medlar, 6 percent of ox kidney, 7 percent of ginseng, 7 percent of dwarf lilyturf tuber, 0.5 percent of tangerine peel, 0.5 percent of xylo-oligosaccharide, 0.1 percent of sodium carboxymethyl cellulose, 0.1 percent of potassium sorbate, 0.2 percent of cordyceps sinensis and 40.6 percent of pure water.
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