CN114364313B - 电极基板及其制造方法以及使用了这种电极基板的生物传感器 - Google Patents

电极基板及其制造方法以及使用了这种电极基板的生物传感器 Download PDF

Info

Publication number
CN114364313B
CN114364313B CN202080063678.8A CN202080063678A CN114364313B CN 114364313 B CN114364313 B CN 114364313B CN 202080063678 A CN202080063678 A CN 202080063678A CN 114364313 B CN114364313 B CN 114364313B
Authority
CN
China
Prior art keywords
region
insulating substrate
uneven structure
fine uneven
fine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202080063678.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN114364313A (zh
Inventor
白井彰人
畑山健
角谷和哉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Puhexi Holdings
Original Assignee
Puhexi Holdings
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Puhexi Holdings filed Critical Puhexi Holdings
Publication of CN114364313A publication Critical patent/CN114364313A/zh
Application granted granted Critical
Publication of CN114364313B publication Critical patent/CN114364313B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/685—Microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/12—Manufacturing methods specially adapted for producing sensors for in-vivo measurements
    • A61B2562/125—Manufacturing methods specially adapted for producing sensors for in-vivo measurements characterised by the manufacture of electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Non-Insulated Conductors (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202080063678.8A 2019-09-18 2020-08-28 电极基板及其制造方法以及使用了这种电极基板的生物传感器 Active CN114364313B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019-169161 2019-09-18
JP2019169161 2019-09-18
PCT/JP2020/032501 WO2021054081A1 (ja) 2019-09-18 2020-08-28 電極基板およびその製造方法、ならびに、そのような電極基板を用いたバイオセンサ

Publications (2)

Publication Number Publication Date
CN114364313A CN114364313A (zh) 2022-04-15
CN114364313B true CN114364313B (zh) 2024-11-29

Family

ID=74883479

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080063678.8A Active CN114364313B (zh) 2019-09-18 2020-08-28 电极基板及其制造方法以及使用了这种电极基板的生物传感器

Country Status (5)

Country Link
US (1) US12222309B2 (https=)
EP (1) EP4033234A4 (https=)
JP (1) JPWO2021054081A1 (https=)
CN (1) CN114364313B (https=)
WO (1) WO2021054081A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102703210B1 (ko) * 2022-01-26 2024-09-04 성균관대학교산학협력단 발수성 생체부착형 점착 패치 및 이의 제조방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6091078A (en) * 1998-04-15 2000-07-18 Tdk Corporation Organic EL display device having separating groove structures between adjacent elements
CN1941384A (zh) * 2005-09-27 2007-04-04 中华映管股份有限公司 有机电致发光显示器及其薄膜晶体管阵列基板的制造方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006011545B4 (de) * 2006-03-14 2016-03-17 Robert Bosch Gmbh Mikromechanisches Kombi-Bauelement und entsprechendes Herstellungsverfahren
US9549746B2 (en) * 2007-09-28 2017-01-24 The Queen's University Of Belfast Delivery device and method
WO2011078265A1 (ja) 2009-12-24 2011-06-30 三菱レイヨン株式会社 有機系離型剤の性能評価方法、モールドの製造方法および微細凹凸構造を表面に有する透明フィルムの製造方法
JP5770055B2 (ja) 2010-09-29 2015-08-26 富士フイルム株式会社 針状アレイ経皮吸収シートの製造方法
JP2014533523A (ja) * 2011-09-02 2014-12-15 ザ レジェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア バイオセンシングおよび薬剤供給のためのマイクロ針アレイ
CN203038965U (zh) * 2012-07-02 2013-07-03 刘艳 发光元件
US10820860B2 (en) 2013-03-14 2020-11-03 One Drop Biosensor Technologies, Llc On-body microsensor for biomonitoring
GB201412696D0 (en) 2014-07-17 2014-09-03 Imp Innovations Ltd Multi-probe microstructed arrays
CN104238816A (zh) * 2014-09-04 2014-12-24 京东方科技集团股份有限公司 一种触控面板及其制作方法
US10172558B2 (en) 2015-09-10 2019-01-08 University Of Utah Research Foundation Structure and methodology for a shadow mask having hollow high aspect ratio projections
CN105607332A (zh) * 2016-01-04 2016-05-25 京东方科技集团股份有限公司 彩膜基板、显示面板和显示装置
EP3449827B1 (en) * 2016-04-27 2020-05-13 PHC Holdings Corporation Sensor insertion device
JP6319368B2 (ja) 2016-06-16 2018-05-09 凸版印刷株式会社 反射型フォトマスクおよびその製造方法
US11512384B2 (en) * 2017-05-11 2022-11-29 Medtronic Minimed, Inc. Analyte sensors and methods for fabricating analyte sensors
US11077475B2 (en) 2017-05-23 2021-08-03 International Business Machines Corporation Neuro-chemical sensor with inhibition of fouling on nano-electrode
US10504737B2 (en) * 2017-05-30 2019-12-10 Taiwan Semiconductor Manufacturing Co., Ltd. Methods of enhancing surface topography on a substrate for inspection
EP3494875A1 (en) 2017-12-11 2019-06-12 ETH Zurich Sensor device for detecting an electrical signal
EP3747364A4 (en) * 2018-01-29 2021-11-10 PHC Holdings Corporation PROTECTIVE FILM MATERIAL FOR BIOCAPTER PROBE
WO2019243902A1 (en) * 2018-06-17 2019-12-26 Abdolahad Mohammad Electrochemical biosensor and method to monitor biological cells behavior in acidic conditions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6091078A (en) * 1998-04-15 2000-07-18 Tdk Corporation Organic EL display device having separating groove structures between adjacent elements
CN1941384A (zh) * 2005-09-27 2007-04-04 中华映管股份有限公司 有机电致发光显示器及其薄膜晶体管阵列基板的制造方法

Also Published As

Publication number Publication date
CN114364313A (zh) 2022-04-15
US20220334076A1 (en) 2022-10-20
JPWO2021054081A1 (https=) 2021-03-25
EP4033234A1 (en) 2022-07-27
EP4033234A4 (en) 2022-11-16
US12222309B2 (en) 2025-02-11
WO2021054081A1 (ja) 2021-03-25

Similar Documents

Publication Publication Date Title
KR100874630B1 (ko) 바이오센서 및 관련된 응용분야를 참고한 그 제조방법
EP1218732B1 (en) Patterned laminates and electrodes with laser defined features
EP1302545B1 (en) Enzyme Biosensor
US7465597B2 (en) Method of manufacturing a diagnostic test strip
TWI454245B (zh) 用於多井生物感測器之化學圖案的系統與方法
AU778920B2 (en) Embedded metallic deposits
WO2008021758A1 (en) Methods for fabricating a biosensor with a surface texture
US10172558B2 (en) Structure and methodology for a shadow mask having hollow high aspect ratio projections
US20230263432A1 (en) Needles for measurement of body fluid analytes such as glucose
JP6603554B2 (ja) 導電性フィルム
CN111272850A (zh) 葡萄糖传感器的工作电极
CN114364313B (zh) 电极基板及其制造方法以及使用了这种电极基板的生物传感器
WO2016065190A1 (en) Electrodes having at least one sensing structure and methods for making and using the same
AU2023246959A1 (en) Optically transparent microelectrode arrays for electrochemical and electrophysiological measurements or stimulation
JP2013154010A (ja) 電気化学センサの製造方法、及び電気化学センサ
JP6149470B2 (ja) バイオセンサ
JP2014215247A (ja) バイオセンサ用電極、バイオセンサおよびバイオセンサ用電極の製造方法
CN102556931B (zh) 电极点间距可超过微加工精度的微电极阵列及其制备方法
Srikantharajah Development, characterization, and application of compliant intracortical implants
JP2015045608A (ja) バイオセンサ用カバーの製造方法、バイオセンサの製造方法、およびバイオセンサ用カバー
CN115175613A (zh) 传感器及其制造方法
CN110935495A (zh) Gaba和电生理微纳同步传感检测芯片及其制备方法
KR20220170585A (ko) 저잡음 신경 전극 및 이의 제조방법
JP6191203B2 (ja) バイオセンサ用電極およびバイオセンサ
HK40111866A (zh) 分析物传感器及其制造方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant