CN114341341A - 细胞制造装置及其制造方法 - Google Patents

细胞制造装置及其制造方法 Download PDF

Info

Publication number
CN114341341A
CN114341341A CN202080062103.4A CN202080062103A CN114341341A CN 114341341 A CN114341341 A CN 114341341A CN 202080062103 A CN202080062103 A CN 202080062103A CN 114341341 A CN114341341 A CN 114341341A
Authority
CN
China
Prior art keywords
cell
fluid
fluid circuit
manufacturing apparatus
unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080062103.4A
Other languages
English (en)
Chinese (zh)
Inventor
伴一训
木下聪
田边刚士
平出亮二
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aipaisi Co
Fanuc Corp
Original Assignee
Aipaisi Co
Fanuc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aipaisi Co, Fanuc Corp filed Critical Aipaisi Co
Publication of CN114341341A publication Critical patent/CN114341341A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/04—Flat or tray type, drawers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/10—Petri dish
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/22—Transparent or translucent parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Computer Hardware Design (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202080062103.4A 2019-08-29 2020-05-28 细胞制造装置及其制造方法 Pending CN114341341A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962893605P 2019-08-29 2019-08-29
US62/893,605 2019-08-29
PCT/JP2020/021240 WO2021038996A1 (ja) 2019-08-29 2020-05-28 細胞製造装置及びその製造方法

Publications (1)

Publication Number Publication Date
CN114341341A true CN114341341A (zh) 2022-04-12

Family

ID=74683626

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080062103.4A Pending CN114341341A (zh) 2019-08-29 2020-05-28 细胞制造装置及其制造方法

Country Status (5)

Country Link
US (1) US20230038829A1 (https=)
EP (1) EP4023741A4 (https=)
JP (1) JP7391339B2 (https=)
CN (1) CN114341341A (https=)
WO (1) WO2021038996A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12258546B2 (en) 2021-12-23 2025-03-25 Industrial Technology Research Institute Cell and tissue sheet forming package and cell injection equipment
TWI796893B (zh) * 2021-12-23 2023-03-21 財團法人工業技術研究院 細胞與組織層片成型包裝與細胞灌注設備
US20240359174A1 (en) * 2022-05-19 2024-10-31 Boe Technology Group Co., Ltd. Gene detection substrate, gene detection chip and method for preparing gene detection sample

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817505A (en) * 1993-05-07 1998-10-06 Bioscot Limited Particle settler for use in cell culture
US6645432B1 (en) * 2000-05-25 2003-11-11 President & Fellows Of Harvard College Microfluidic systems including three-dimensionally arrayed channel networks
JP2005287425A (ja) * 2004-03-31 2005-10-20 Koojin Bio Kk 培地バッグ付き培養バッグ
WO2006043642A1 (ja) * 2004-10-20 2006-04-27 Ebara Corporation 流体反応装置
JP2007136322A (ja) * 2005-11-17 2007-06-07 Konica Minolta Medical & Graphic Inc 反応物質同士の拡散および反応を効率化したマイクロリアクタ、およびそれを用いた反応方法
WO2013175580A1 (ja) * 2012-05-23 2013-11-28 株式会社日立製作所 培養容器及び自動培養装置
CN103667054A (zh) * 2013-09-18 2014-03-26 中国航天员科研训练中心 一种集成化微流控细胞培养芯片及其制备方法
JP2014064475A (ja) * 2012-09-24 2014-04-17 Terumo Corp 膜状組織の保存輸送容器および保存輸送方法
JP2017046592A (ja) * 2014-01-09 2017-03-09 東京エレクトロン株式会社 細胞培養容器および細胞継代培養システム並びに細胞継代培養方法
CN107849505A (zh) * 2015-04-22 2018-03-27 伯克利之光生命科技公司 微流体细胞培养
CN108138113A (zh) * 2015-08-31 2018-06-08 爱平世股份有限公司 多能性干细胞制造系统
CN108779421A (zh) * 2016-03-08 2018-11-09 国立研究开发法人产业技术综合研究所 细胞培养装置以及细胞培养方法
CN109153959A (zh) * 2016-05-02 2019-01-04 整合培育株式会社 生长诱导系统、生长诱导控制装置、生长诱导控制方法和生长诱导控制程序
WO2019043130A1 (en) * 2017-08-31 2019-03-07 Philip Morris Products S.A. CELL CULTURE PLATE, IN VITRO EXPOSURE DEVICES AND METHODS

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808836D0 (en) 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
WO2003087292A2 (en) * 2002-04-08 2003-10-23 Millenium Biologix Inc. Automated tissue engineering system
JP4294425B2 (ja) 2003-09-10 2009-07-15 独立行政法人農業・食品産業技術総合研究機構 細胞培養プレート
US7588671B2 (en) 2003-11-21 2009-09-15 Ebara Corporation Microfluidic treatment method and device
KR20080072022A (ko) 2005-11-01 2008-08-05 가부시키가이샤 메디넷 세포배양장치, 세포배양방법, 세포배양프로그램, 및세포배양시스템
US8048999B2 (en) 2005-12-13 2011-11-01 Kyoto University Nuclear reprogramming factor
JP5722329B2 (ja) 2010-08-12 2015-05-20 株式会社日立製作所 自動培養装置
EP4151716A1 (en) * 2011-05-06 2023-03-22 EMD Millipore Corporation Automatic aseptic sampling valve for sampling from enclosed containers
WO2014049701A1 (ja) 2012-09-26 2014-04-03 株式会社日立製作所 細胞培養容器およびそれを用いた細胞培養装置
JP6366226B2 (ja) 2013-05-24 2018-08-01 株式会社島津製作所 マイクロチップ反応装置
EP3233280B1 (en) * 2014-12-18 2021-03-17 Global Life Sciences Solutions Operations UK Ltd Devices, methods and systems for collecting waste from a bioreactor
SG11201708429WA (en) 2015-04-22 2017-11-29 Berkeley Lights Inc Microfluidic cell culture
US11225638B2 (en) * 2016-04-04 2022-01-18 CyteQuest, Inc. System, device and method for electroporation of cells
US11408812B2 (en) * 2016-04-22 2022-08-09 Becton, Dickinson And Company High density deposition for array production
JP6202505B1 (ja) 2016-06-17 2017-09-27 株式会社アイカムス・ラボ 細胞培養装置
US11259520B2 (en) 2016-08-04 2022-03-01 Fanuc Corporation Stem cell manufacturing system, stem cell information management system, cell transport apparatus, and stem cell frozen storage apparatus
CA3053891C (en) 2017-02-27 2023-05-23 I Peace, Inc. Somatic cell production system
US20190185805A1 (en) * 2017-12-19 2019-06-20 Infinitesimal Llc Automated electroporation of single cells in micro-well plates
GB2585302B (en) * 2018-02-23 2023-03-22 Emulate Inc Organs-on-chips as a platform for epigenetics discovery
EP3842526A4 (en) * 2018-08-20 2022-05-25 I Peace, Inc. Method for cultivating or inducing cells
EP3842513A4 (en) * 2018-08-20 2022-06-29 I Peace, Inc. Cell incubator

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817505A (en) * 1993-05-07 1998-10-06 Bioscot Limited Particle settler for use in cell culture
US6645432B1 (en) * 2000-05-25 2003-11-11 President & Fellows Of Harvard College Microfluidic systems including three-dimensionally arrayed channel networks
JP2005287425A (ja) * 2004-03-31 2005-10-20 Koojin Bio Kk 培地バッグ付き培養バッグ
WO2006043642A1 (ja) * 2004-10-20 2006-04-27 Ebara Corporation 流体反応装置
JP2007136322A (ja) * 2005-11-17 2007-06-07 Konica Minolta Medical & Graphic Inc 反応物質同士の拡散および反応を効率化したマイクロリアクタ、およびそれを用いた反応方法
WO2013175580A1 (ja) * 2012-05-23 2013-11-28 株式会社日立製作所 培養容器及び自動培養装置
JP2014064475A (ja) * 2012-09-24 2014-04-17 Terumo Corp 膜状組織の保存輸送容器および保存輸送方法
CN103667054A (zh) * 2013-09-18 2014-03-26 中国航天员科研训练中心 一种集成化微流控细胞培养芯片及其制备方法
JP2017046592A (ja) * 2014-01-09 2017-03-09 東京エレクトロン株式会社 細胞培養容器および細胞継代培養システム並びに細胞継代培養方法
CN107849505A (zh) * 2015-04-22 2018-03-27 伯克利之光生命科技公司 微流体细胞培养
CN108138113A (zh) * 2015-08-31 2018-06-08 爱平世股份有限公司 多能性干细胞制造系统
CN108779421A (zh) * 2016-03-08 2018-11-09 国立研究开发法人产业技术综合研究所 细胞培养装置以及细胞培养方法
CN109153959A (zh) * 2016-05-02 2019-01-04 整合培育株式会社 生长诱导系统、生长诱导控制装置、生长诱导控制方法和生长诱导控制程序
WO2019043130A1 (en) * 2017-08-31 2019-03-07 Philip Morris Products S.A. CELL CULTURE PLATE, IN VITRO EXPOSURE DEVICES AND METHODS

Also Published As

Publication number Publication date
EP4023741A1 (en) 2022-07-06
EP4023741A4 (en) 2023-11-08
WO2021038996A1 (ja) 2021-03-04
US20230038829A1 (en) 2023-02-09
JP7391339B2 (ja) 2023-12-05
JPWO2021038996A1 (https=) 2021-03-04

Similar Documents

Publication Publication Date Title
ES2761938T3 (es) Método y sistema para la producción de células
KR102383028B1 (ko) 일회용 용기 내 업스트리임 및 다운스트리임 처리
EP3307864B1 (en) Cell culture incubator and cell culture method
CN107904170B (zh) 细胞培养模块及细胞培养系统
CN114341341A (zh) 细胞制造装置及其制造方法
CN113165374B (zh) 用于3d生物打印机的打印头组件
JP2023501142A (ja) 細胞含有流体のエレクトロポレーションのためのシステム、方法、及びデバイス
CN101835886A (zh) 用于灌注的中等尺寸生物反应器平台
EP2245453A2 (en) Cell culture array system for automated assays and methods of operation and manufacture thereof
CN104053764A (zh) 生物工程和医疗模块化系统
US12486485B2 (en) Cell treatment device, suspension culture vessel, and stem cell induction method
US20220306981A1 (en) Erythrocyte removal device, mononuclear cell collector, cell culture device, cell culture system, cell culture method, and method for collecting mononuclear cells
JP7297272B2 (ja) 細胞製造装置
EP4023747A1 (en) Cell production device and system therefor
HK40070124A (en) Cell production device and cell production method
JP7041325B2 (ja) 細胞培養器及び細胞培養装置
HK40070127A (en) Cell production device and system therefor
HK40070126A (en) Cell production device
EP4481029A1 (en) Method for controlling fluid displacement and gas(es) composition and/or ph in a cell culture device and corresponding cell culture system
HK40118839A (en) Method for controlling fluid displacement and gas(es) composition and/or ph in a cell culture device and corresponding cell culture system
US20250101354A1 (en) Bioreactor for producing a biological medicament, and support for such a bioreactor
US12454681B2 (en) Erythrocyte removal device, mononuclear cell collector, cell culture device, cell culture system, cell culture method, and mononuclear cell collection method
WO2023192899A2 (en) Microwell-based multi-tissue platform
HK40057644B (zh) 红细胞除去装置、单核细胞回收器、细胞培养装置、细胞培养系统
HK40056621B (zh) 细胞培养装置的应用

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40070124

Country of ref document: HK