CN114317258B - Combination pipe, combination pipe belt and detection device - Google Patents
Combination pipe, combination pipe belt and detection device Download PDFInfo
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- CN114317258B CN114317258B CN202210213617.6A CN202210213617A CN114317258B CN 114317258 B CN114317258 B CN 114317258B CN 202210213617 A CN202210213617 A CN 202210213617A CN 114317258 B CN114317258 B CN 114317258B
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Abstract
The invention provides a combined pipe, which relates to the technical field of microbial detection and comprises the following components: the device comprises a plurality of first liquid guide pipes, a plurality of reaction pipes, an exhaust pipe and at least one liquid inlet pipe, wherein the first liquid guide pipes and the reaction pipes are the same in quantity and are arranged in a one-to-one correspondence manner, one end of one reaction pipe is detachably connected and communicated with one end of one first liquid guide pipe, the other end of the reaction pipe is communicated with one end of the exhaust pipe, the other end of the first liquid guide pipe is communicated with one end of the liquid inlet pipe, one end of the exhaust pipe, which is not connected with the reaction pipe, is communicated with an exhaust opening of a vacuum pump, one end of the liquid inlet pipe, which is not connected with the first liquid guide pipe, is used for being placed in a sample bottle to suck a fluid sample, and the types of reaction reagents embedded in the plurality of reaction pipes are not completely the same; the combined tube, the combined tube belt and the detection device are convenient for embedding a reaction reagent and simultaneously performing multiple detections on a sample to be detected.
Description
Technical Field
The invention relates to the technical field of microorganism detection, in particular to a combined tube, a combined tube belt and a detection device.
Background
Microfluidics is also called as microfluidic chip technology, and can integrate basic operation units of sample preparation, reaction, separation, detection and the like in biological, chemical and medical analysis processes on a chip which is divided into a plurality of equal parts, so that controllable fluid can penetrate through the whole system to replace various functions of a conventional chemical or biological laboratory. Currently, microfluidics is widely used in the field of detection.
When one chip of the existing microfluidic chip has a plurality of reaction chambers at the same time, the sample to be detected generally needs to be repeatedly added with sample or centrifuged, so that the sample to be detected enters different reaction chambers, the operation is complicated, the consumed time is long, and the detection progress is influenced; meanwhile, different detection reagents are embedded in different reaction chambers of the same chip, so that the difficulty is high, and the simultaneous multiple detection of a sample to be detected is not facilitated.
Disclosure of Invention
The invention aims to provide a combined tube, a combined tube strip and a detection device, which are used for solving the problems in the prior art, so that a reaction reagent can be embedded conveniently and a sample to be detected can be detected conveniently and simultaneously.
In order to achieve the purpose, the invention provides the following scheme:
the present invention provides a composite tube comprising: the device comprises a plurality of first liquid guide pipes, a plurality of reaction pipes, an exhaust pipe and at least one liquid inlet pipe, wherein the first liquid guide pipes and the reaction pipes are the same in quantity, the first liquid guide pipes and the reaction pipes are arranged in a one-to-one correspondence mode, one end of one reaction pipe is detachably connected and communicated with one end of one first liquid guide pipe, the other end of each reaction pipe is communicated with one end of the corresponding exhaust pipe, the other end of each first liquid guide pipe is communicated with one end of the corresponding liquid inlet pipe, one end, which is not connected with the corresponding reaction pipe, of the corresponding exhaust pipe is communicated with an exhaust opening of a vacuum pump, one end, which is not connected with the corresponding first liquid guide pipe, of the corresponding liquid inlet pipe is used for being placed in a sample bottle to suck a fluid sample, a reaction reagent is embedded in each reaction pipe, and the types of primers embedded in the reaction pipes are not completely the same.
Preferably, the reaction device further comprises a first buffer chamber, a plurality of the first liquid guide pipes are arranged side by side, a plurality of the reaction pipes are also arranged side by side, the length of the first buffer chamber is not less than the total width of the plurality of the first liquid guide pipes, the plurality of the first liquid guide pipes are sequentially arranged along the length direction of the first buffer chamber, one end of the first liquid guide pipe, which is not communicated with the reaction pipe, is directly communicated with one side of the first buffer chamber, and the middle part of the other side of the first buffer chamber is communicated with one end of the liquid inlet pipe.
Preferably, the reaction device further comprises a second buffer chamber and a plurality of second liquid guide pipes, the number of the second liquid guide pipes is the same as that of the reaction pipes, the second liquid guide pipes are arranged on one side, far away from the first liquid guide pipe, of the reaction pipes side by side, one ends of the second liquid guide pipes are detachably connected and communicated with one ends, not connected with the first liquid guide pipe, of the reaction pipes, the length of the second buffer chamber is not smaller than the total width of the plurality of second liquid guide pipes, the plurality of second liquid guide pipes are sequentially arranged and distributed along the length direction of the second buffer chamber, one ends, not communicated with the reaction pipes, of the second liquid guide pipes are directly communicated with one side of the second buffer chamber, and the middle part of the other side of the second buffer chamber is communicated with one end of the exhaust pipe.
Preferably, the inner diameters of the second liquid guide tube and the first liquid guide tube are smaller than the inner diameter of the reaction tube, the corresponding second liquid guide tube, the corresponding reaction tube and the corresponding first liquid guide tube are coaxially arranged, the inner wall of the second liquid guide tube is a hydrophobic surface, the inner wall of the reaction tube is a hydrophilic surface, and the second liquid guide tube and the corresponding first liquid guide tube are respectively inserted at two ends of the reaction tube.
The invention also provides a combined pipe belt, which comprises a plurality of combined pipes, wherein the combined pipes are sequentially connected in series to form the combined pipe belt in a belt shape, the liquid inlet pipe in the combined pipe at the head end of the combined pipe belt is used for being placed in a sample bottle to suck a fluid sample, and the air exhaust pipe in the combined pipe at the tail end of the combined pipe belt is used for being communicated with the air exhaust port of the vacuum pump;
the air suction pipes in the other combined pipes except the combined pipe at the tail end are connected and communicated with the liquid inlet pipe in the other combined pipe, and the liquid inlet pipes in the other combined pipes except the combined pipe at the head end are connected and communicated with the air suction pipes in the other combined pipe.
The invention also provides a detection device, which comprises a roller, a detection platform and the combined pipe belt; the exhaust tube with the feed liquor pipe is the flexible hose that can deform, the combination pipe area is around locating on the gyro wheel, the gyro wheel can free rotation, the combination pipe of combination pipe area head end is used for laying in carry out test on the testing platform.
Preferably, the detection platform is provided with a limit groove, the shape and size of the limit groove are matched with those of the combined pipe, and the combined pipe can be embedded and fixed in the limit groove.
Preferably, the detection platform is further provided with two pressing plates, the two pressing plates can respectively fix the liquid inlet pipe at the head end of the combined pipe in the combined pipe and the liquid inlet pipe connected with the head end of the combined pipe in the combined pipe on the detection platform, one end of each pressing plate is hinged to the detection platform, and the other end of each pressing plate can be clamped on the detection platform through a clamping structure.
Preferably, the combined pipe belt is provided with two adjacent combined pipes, the exhaust pipe and the liquid inlet pipe are integrally formed, and the detection platform is further provided with a temperature control plate which is used for heating the reaction pipe.
Preferably, the detection platform is further provided with a cutting plate, and the cutting plate is used for cutting the combined pipe at the head end from the liquid inlet pipe on the combined pipe connected with the combined pipe at the head end.
Compared with the prior art, the invention achieves the following technical effects:
the combined tube provided by the invention comprises a plurality of reaction tubes, wherein reaction reagents are embedded in the reaction tubes, the types of the reaction reagents embedded in the reaction tubes are not completely the same, so that a sample to be detected can be detected in multiple ways, and the reaction tubes are detachably connected with the first liquid guide tube, so that a worker can add the reaction reagents into the reaction tubes through the connecting ports of the reaction tubes and the first liquid guide tube.
Furthermore, one end of the reaction tube, which is not connected with the first liquid guide tube, can also be detachably connected and communicated with the second liquid guide tube, so that the reaction tubes can be embedded with reaction reagents in batches before the combination tube is formed and then combined into the combination tube, and the convenience for manufacturing the combination tube is improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments will be briefly described below.
FIG. 1 is a schematic structural diagram of a combined pipe belt according to a second embodiment;
fig. 2 is a schematic structural diagram of a detection apparatus according to a third embodiment;
FIG. 3 is a schematic view of a combination tube resting on an inspection platform;
FIG. 4 is a schematic view of the combined pipe belt wound around the roller and the internal structure of the roller;
FIG. 5 is a schematic structural diagram of a composite pipe according to an embodiment;
FIG. 6 is a schematic view of an internal structure of a composite pipe according to an embodiment;
in the figure: 1-combined tube, 2-roller, 3-detection platform, 4-pressing plate, 5-cutting plate, 6-limiting groove, 7-sample bottle, 8-combined tube belt, 9-supporting structure, 10-buckle structure, 11-air exhaust tube, 12-liquid inlet tube, 13-reaction tube, 14-first buffer chamber, 15-first liquid guide tube, 16-second liquid guide tube and 17-second buffer chamber.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention aims to provide a combined tube, a combined tube strip and a detection device, which are used for solving the problems in the prior art, so that a reaction reagent can be embedded conveniently and a sample to be detected can be detected conveniently and simultaneously.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Example one
The present embodiment provides a composite pipe 1 including: the device comprises a plurality of first liquid guide tubes 15, a plurality of reaction tubes 13, an exhaust tube 11 and at least one liquid inlet tube 12, wherein the first liquid guide tubes 15 and the reaction tubes 13 are the same in quantity, the first liquid guide tubes 15 and the reaction tubes 13 are arranged in a one-to-one correspondence manner, one end of one reaction tube 13 can be detachably connected and communicated with one end of one first liquid guide tube 15, the other end of the reaction tube 13 is communicated with one end of the exhaust tube 11, the other end of the first liquid guide tube 15 is communicated with one end of the liquid inlet tube 12, one end of the exhaust tube 11, which is not connected with the reaction tubes 13, is communicated with an exhaust port of a vacuum pump, one end of the liquid inlet tube 12, which is not connected with the first liquid guide tube 15, is used for being placed in a sample bottle 7 to suck a fluid sample, a reaction reagent is embedded in each of the plurality of reaction tubes 13, and the types of the reaction reagents embedded in the plurality of reaction tubes 13 are not completely the same. During the use, the reaction intracavity embedding in the different reaction tube 13 has different reaction reagent, then opens the vacuum pump, and the vacuum pump takes out the gas in a plurality of reaction chambeies through exhaust tube 11, and the reaction chamber inhales the sample in sample bottle 7 to the reaction chamber under the state of vacuum negative pressure and carries out the testing, and a plurality of reaction chambers are the parallel relation, and a plurality of reaction chambers inhale the sample simultaneously, and it can to close the vacuum pump after inhaling the sufficient sample in the reaction chamber.
The combination pipe 1 that this embodiment provided includes a plurality of reaction tubes 13, all embed reagent in a plurality of reaction tubes 13, the embedded reagent kind is not identical in a plurality of reaction tubes 13, so that do multiple detection to the sample that awaits measuring simultaneously, and reaction tubes 13 can dismantle with first catheter 15 and be connected, so that the staff adds reagent through reaction tubes 13 and first catheter 15's connector in to reaction tubes 13, consequently, the scheme that this embodiment provided is convenient for carry out the embedding to reagent and is convenient for do multiple detection to the sample that awaits measuring simultaneously.
Further, the combination tube 1 further includes a first buffer chamber 14, the plurality of first liquid guide tubes 15 are arranged side by side, the plurality of reaction tubes 13 are also arranged side by side, the length of the first buffer chamber 14 is not less than the total width of the plurality of first liquid guide tubes 15, the plurality of first liquid guide tubes 15 are sequentially arranged and distributed along the length direction of the first buffer chamber 14, one end of the first liquid guide tube 15, which is not communicated with the reaction tubes 13, is directly communicated with one side of the first buffer chamber 14, the middle part of the other side of the first buffer chamber 14 is communicated with one end of the liquid inlet tube 12, the first buffer chamber 14 buffers the fluid sample flowing from the liquid inlet tube 12 and then flows into each first liquid guide tube 15, and the first buffer chamber 14 is arranged to improve the consistency of the amount of the sample sucked in each reaction chamber.
Furthermore, the combination tube 1 further comprises a second buffer chamber 17 and a plurality of second liquid guide tubes 16, the number of the second liquid guide tubes 16 is the same as that of the reaction tubes 13, the second liquid guide tubes 16 are all arranged at one side of the reaction tubes 13 far away from the first liquid guide tube 15 side by side, one end of each second liquid guide tube 16 is detachably connected and communicated with one end of the reaction tube 13 which is not connected with the first liquid guide tube 15, the length of the second buffer chamber 17 is not less than the total width of the plurality of second liquid guide tubes 16, the plurality of second liquid guide tubes 16 are sequentially arranged along the length direction of the second buffer chamber 17, one end of each second liquid guide tube 16 which is not connected with the reaction tube 13 is directly communicated with one side of the second buffer chamber 17, the middle part of the other side of the second buffer chamber 17 is communicated with one end of the extraction tube 11, the second buffer chamber 17 is arranged for uniformly extracting air from each reaction chamber, and the inner diameters of the second liquid guide tubes 16 and the first liquid guide tubes 15 are both less than the inner diameter of the reaction tubes 13, and the corresponding second liquid guide tube 16, the reaction tube 13 and the first liquid guide tube 15 are coaxially arranged, the inner wall of the second liquid guide tube 16 is a hydrophobic surface, the inner wall of the reaction tube 13 is a hydrophilic surface, so that a sample is not easy to flow out of the reaction tube 13, and the second liquid guide tube 16 and the first liquid guide tube 15 are respectively inserted at two ends of the reaction tube 13, so that the three tubes are combined.
Furthermore, the liquid inlet pipe 12 and the first liquid guide pipe 15 can be set as capillary tubes, so that micro-sampling can be conveniently carried out, and the sampling precision is higher.
During production, different primers and reaction reagents can be embedded into the reaction tubes 13 in batches respectively, and then the reaction tubes 13 embedded with the different primers and the reaction reagents are combined on the liquid guide tube of the same combined tube 1, so that the mass production and assembly are facilitated, and various detections can be performed on a sample to be detected simultaneously.
Example two
The embodiment provides a combined pipe belt, which comprises a plurality of combined pipes 1 described in the first embodiment, wherein the combined pipes 1 are sequentially connected in series to form a belt-shaped combined pipe belt 8, a liquid inlet pipe 12 in the combined pipe 1 at the head end of the combined pipe belt 8 is used for being placed in a sample bottle 7 to suck a fluid sample, and an air exhaust pipe 11 in the combined pipe 1 at the tail end of the combined pipe belt 8 is used for being communicated with an air exhaust port of a vacuum pump;
except the tail combined pipe 1, the air exhaust pipes 11 in the other combined pipes 1 are connected and communicated with the liquid inlet pipe 12 in the other combined pipe 1, and except the head combined pipe 1, the liquid inlet pipes 12 in the other combined pipes 1 are connected and communicated with the air exhaust pipes 11 in the other combined pipe 1.
When the combined pipe belt 8 is used, the exhaust pipe 11 in the tail combined pipe 1 is connected to a vacuum pump and then can be used from the combined pipe 1 at the head end, after one combined pipe 1 is used up, the waste combined pipe 1 can be cut off and discarded or placed beside for subsequent observation, the scheme does not need to repeatedly disassemble and assemble the exhaust pipe 11 and the vacuum pump frequently, and the detection efficiency is further accelerated.
EXAMPLE III
The embodiment provides a detection device, which comprises a roller 2, a detection platform 3 and a combined pipe belt 8 in the second embodiment; exhaust tube 11 and feed liquor pipe 12 are the flexible hose, and combination pipe area 8 is around locating on gyro wheel 2, and this setting has reduced the shared space of combination pipe area 8, and is convenient for accomodate, and gyro wheel 2 can the free rotation, and the combination pipe 1 of combination pipe area 8 head end is used for shelving and carries out the testing on detection platform 3.
When the combined pipe belt is used, the combined pipe 1 at the head end of the combined pipe belt 8 is placed on the detection platform 3 for detection test, after the combined pipe belt is used, the combined pipe 1 is manually removed, and the next combined pipe 1 is pulled to be placed on the detection platform 3 for detection test.
Furthermore, a limit groove 6 is formed in the detection platform 3, the shape and the size of the limit groove 6 are matched with those of the combined pipe 1, and the combined pipe 1 is embedded and fixed in the limit groove 6, so that the combined pipe 1 is prevented from moving to influence a test result when a detection test is carried out.
Further, still be equipped with two clamp plates 4 on testing platform 3, two clamp plates 4 are located two 4 storehouses of clamp plate respectively, two clamp plates 4 can compress tightly on being fixed in testing platform 3 with feed liquor pipe 12 in the combination pipe 1 of 8 head ends of combination pipe racks and the feed liquor pipe 12 in the combination pipe 1 that is connected with the combination pipe 1 of head end respectively, 4 one ends of clamp plate are articulated to be connected on testing platform 3, the other end can pass through buckle structure 10 joint on testing platform 3 to fix combination pipe 1.
Further, the exhaust tube 11 and the liquid inlet tube integrated into one piece between two adjacent combination pipes 1 of combination pipe belt 8 are provided with a temperature control plate on the detection platform 3, and the temperature control plate is used for heating the reaction tube 13.
Further, a cutting plate 5 is further arranged on the detection platform 3, and the cutting plate 5 is used for cutting the combined pipe 1 at the head end down from a liquid inlet pipe 12 on the combined pipe 1 connected with the combined pipe 1 at the head end.
Further, one side of testing platform 3 can set up a garbage bin, is used for holding discarded combination pipe 1 in the garbage bin, and sample bottle 7 can be placed on the garbage bin bung lid, improves the liquid level of sample in the sample bottle 7 to the sample flow direction reaction chamber.
Further, the roller 2 is of a hollow structure, a supporting structure 9 is fixedly arranged on the roller 2, a gas flow passage is arranged in the supporting structure 9, a gas inlet of the gas flow passage is communicated with a gas exhaust pipe 11 at the tail end of the combined pipe belt 8, and a gas outlet of the gas flow passage is communicated with a gas exhaust port of the vacuum pump.
The use steps are as follows:
1. pulling the combined pipe belt 8 on the roller 2, placing one combined pipe 1 on the detection platform 3, and fixing the combined pipe 1 in the limiting groove 6 on the detection platform 3;
2. connecting a vacuum pump with an air outlet of an air flow channel on the roller 2, and extending the tail end of an liquid inlet pipe 12 of the combined pipe 1 on the detection platform 3 into a sample bottle 7 of a sample to be detected;
3. starting a vacuum pump, and sucking a sample to be detected into a reaction tube 13 on the detection platform 3; because each combined tube 1 in the combined tube strip 8 is in closed connection, after the vacuum pump is started, negative pressure is formed in the combined tube 1, so that a sample to be detected can be sucked into a reaction cavity of the combined tube 1;
4. the vacuum pump is closed, the sample bottle 7 is removed, and the pressure plate 4 is used for clamping the air exhaust pipe 11 and/or the liquid inlet pipe 12;
5. the temperature control plate starts heating, and the reaction tube 13 carries out detection reaction;
6. after the reaction is finished, the combined pipe 1 at the head end is cut off from the whole combined pipe belt 8 by using the cutting plate 5, so that the combined pipe 1 after the reaction is finished is separated from other combined pipes 1;
7. the pressing plate 4 and the cutting plate 5 are lifted, and the combined tube 1 after the reaction is finished is taken down from the detection platform 3 and discarded.
In the working flow, the reaction result can be observed directly by naked eyes after the reaction is finished according to different reaction reagents, and the reaction tube 13 can be taken out from the detection platform and placed in a suitable detector for observation after the reaction is finished.
The principle and the implementation mode of the invention are explained by applying a specific example, and the description of the embodiment is only used for helping to understand the method and the core idea of the invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the above, the present disclosure should not be construed as limiting the invention.
Claims (9)
1. A combination pipe strap which characterized in that: comprises a plurality of combined pipes, wherein the combined pipes comprise a plurality of first liquid guide pipes, a plurality of reaction pipes, an air exhaust pipe and at least one liquid inlet pipe, the first liquid guide pipes and the reaction pipes are in the same number, the first liquid guide pipes and the reaction pipes are arranged in a one-to-one correspondence manner, one end of one reaction pipe is detachably connected and communicated with one end of one first liquid guide pipe, the other end of the reaction tube is communicated with one end of the exhaust tube, the other end of the first liquid guide tube is communicated with one end of the liquid inlet tube, one end of the exhaust pipe, which is not connected with the reaction pipes, is communicated with an exhaust port of a vacuum pump, one end of the liquid inlet pipe, which is not connected with the first liquid guide pipe, is used for being placed in a sample bottle to absorb a fluid sample, reaction reagents are embedded in the reaction pipes, and the types of the reaction reagents embedded in the reaction pipes are not completely the same;
the combined pipes are sequentially connected in series to form a belt-shaped combined pipe belt, the liquid inlet pipe in the combined pipe at the head end of the combined pipe belt is used for being placed in a sample bottle to suck a fluid sample, and the air exhaust pipe in the combined pipe at the tail end of the combined pipe belt is used for being communicated with an air exhaust port of a vacuum pump;
the air suction pipes in the other combined pipes except the combined pipe at the tail end are connected and communicated with the liquid inlet pipe in the other combined pipe, and the liquid inlet pipes in the other combined pipes except the combined pipe at the head end are connected and communicated with the air suction pipes in the other combined pipe.
2. The modular tube strip of claim 1, wherein: the combined pipe further comprises a first buffer chamber, a plurality of first liquid guide pipes are arranged side by side, a plurality of reaction pipes are also arranged side by side, the length of the first buffer chamber is not smaller than the total width of the plurality of first liquid guide pipes, the plurality of first liquid guide pipes are sequentially arranged along the length direction of the first buffer chamber, the first liquid guide pipes are not communicated with one ends of the reaction pipes and are directly communicated with one side of the first buffer chamber, and the middle part of the other side of the first buffer chamber is communicated with one end of the liquid inlet pipe.
3. The modular tube strip of claim 1, wherein: the combined pipe further comprises a second buffer chamber and a plurality of second liquid guide pipes, the number of the second liquid guide pipes is the same as that of the reaction pipes, the second liquid guide pipes are arranged on one side, far away from the first liquid guide pipe, of the reaction pipes side by side, one ends of the second liquid guide pipes are detachably connected and communicated with one ends, not connected with the first liquid guide pipe, of the reaction pipes, the length of the second buffer chamber is not smaller than the total width of the plurality of second liquid guide pipes, the plurality of second liquid guide pipes are sequentially arranged in the length direction of the second buffer chamber, one ends, not communicated with the reaction pipes, of the second liquid guide pipes are directly communicated with one side of the second buffer chamber, and the middle of the other side of the second buffer chamber is communicated with one end of the exhaust pipe.
4. The modular tube strip of claim 3, wherein: the inner diameters of the second liquid guide pipe and the first liquid guide pipe are smaller than the inner diameter of the reaction pipe, the second liquid guide pipe, the reaction pipe and the first liquid guide pipe are arranged coaxially, the inner wall of the second liquid guide pipe is a hydrophobic surface, the inner wall of the reaction pipe is a hydrophilic surface, and the second liquid guide pipe and the first liquid guide pipe are respectively inserted at two ends of the reaction pipe in a cuttage mode.
5. A detection device, characterized by: the combined pipe belt comprises rollers, a detection platform and the combined pipe belt according to any one of claims 1 to 4; the exhaust tube with the feed liquor pipe is the flexible hose that can deform, the combination pipe area is around locating on the gyro wheel, the gyro wheel can free rotation, the combination pipe of combination pipe area head end is used for laying in carry out test on the testing platform.
6. The detection device according to claim 5, wherein: the detection platform is provided with a limiting groove, the shape and the size of the limiting groove are matched with those of the combined pipe, and the combined pipe can be embedded and fixed in the limiting groove.
7. The detection device according to claim 5, wherein: the detection platform is further provided with two pressing plates, the two pressing plates can respectively fix the liquid inlet pipe at the head end of the combined pipe in the combined pipe and the liquid inlet pipe connected with the head end of the combined pipe in the combined pipe on the detection platform, one end of each pressing plate is hinged to the detection platform, and the other end of each pressing plate can be clamped on the detection platform through a clamping structure.
8. The detection device according to claim 7, wherein: the gas extraction pipe and the liquid inlet pipe between two adjacent combined pipes of the combined pipe belts are integrally formed; the detection platform is also provided with a temperature control plate, and the temperature control plate is used for heating the reaction tube.
9. The detection device according to claim 7, wherein: the detection platform is further provided with a cutting plate, and the cutting plate is used for cutting the combined pipe at the head end down from the liquid inlet pipe on the combined pipe connected with the combined pipe at the head end.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210213617.6A CN114317258B (en) | 2022-03-07 | 2022-03-07 | Combination pipe, combination pipe belt and detection device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210213617.6A CN114317258B (en) | 2022-03-07 | 2022-03-07 | Combination pipe, combination pipe belt and detection device |
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| CN114317258A CN114317258A (en) | 2022-04-12 |
| CN114317258B true CN114317258B (en) | 2022-08-02 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB2077914A (en) * | 1978-05-25 | 1981-12-23 | Dynatech Ag | A miniature reaction container and a method and apparatus for introducing micro volumes of liquid to such a container |
| US7138254B2 (en) * | 1999-08-02 | 2006-11-21 | Ge Healthcare (Sv) Corp. | Methods and apparatus for performing submicroliter reactions with nucleic acids or proteins |
| WO2016031705A1 (en) * | 2014-08-26 | 2016-03-03 | ユニバーサル・バイオ・リサーチ株式会社 | Magnetic particle reaction control apparatus utilizing variable-pitch dispensing apparatus and reaction control method therefor |
| CN211463116U (en) * | 2019-12-13 | 2020-09-11 | 常州那央生物科技有限公司 | Premixing device and tubular micro-reactor with same |
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