CN1142368A - External using medicine for pruritus genitalium - Google Patents
External using medicine for pruritus genitalium Download PDFInfo
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- CN1142368A CN1142368A CN 95109270 CN95109270A CN1142368A CN 1142368 A CN1142368 A CN 1142368A CN 95109270 CN95109270 CN 95109270 CN 95109270 A CN95109270 A CN 95109270A CN 1142368 A CN1142368 A CN 1142368A
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- fructus
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Abstract
An exterior-use medicine for treating pudendal itch with high cure rate, low recurrence rate, quick acting and short course of treatment is prepared through seeping flavescent sophora root with acetic acid to obtain seeped liquid, seeping broom cypress fruit and brucea fruit with alcohol to collect seeped liquid, decoction in water and alcohol deposition of cnidium fruit to take supernatant, immersing common fibraurea stem in sulfuric acid to extract fibraminine, then mixing them together, adding menthol and hibitane acetate or ethyl nipagin or benzoic acid, and mixing uniformly.
Description
The invention belongs to medicine for external use of a kind of women's of treatment pudendal pruritus and preparation method thereof
Pudendal pruritus is meant women's external genital or intravaginal pruritus, is common gynecological disease, frequently-occurring disease.Primary disease is many to be accumulate due to long-pending or the wind syndrome due to blood-deficiency dryness-transformation because of damp and hot, is often concurrent symptoms of patients such as modern medicine colpitis mycotica, trichomonal vaginitis, senile vaginitis, infantile vaginitis, leukoplakia vulvae.For this disease, how to treat clinically at present with the external treatment medicine, as fumigation and wash method, immersion, demibain, scouring etc., be that the course of treatment is long owing to use these medicines treatment majorities, relapse rate height after curing is cured the symptoms, not the disease, and on the high side, is difficult to be accepted by the patient.
The objective of the invention is according to Chinese medical theory, to suppress killing infusorian, mycete and staphylococcus aureus etc. is target, the good recipe for the treatment of women's pudendal pruritus is at all times analyzed, screened and provide a kind of instant effect, short treating period not only takes stopgap measures but also effect a permanent cure, the cure rate height, it is low to cure the back relapse rate, easy to use, low price is easy to a kind of medicine for external use for the treatment of pudendal pruritus of being accepted by the patient.
The present invention is achieved in that
Radix Sophorae Flavescentis is with 8～10 times of percolation of 0.5～5% acetic acid, and Radix Sophorae Flavescentis percolate yield is approximately 50～80% of former acetic acid weight;
The Fructus Kochiae, Fructus Bruceae half and half, with 8～10 times of percolation of 5～20% ethanol, Fructus Kochiae crow gallbladder mixing percolate yield is approximately 50～80% of former amount of alcohol;
Fructus Cnidii, decocting in water, it is 1.13～1.15 o'clock adding ethanol that water cooking liquid is concentrated to relative density, makes the ethanol content in the water cooking liquid reach 70～90%, carries out precipitate with ethanol then and gets its supernatant, Fructus Cnidii decocting in water alcohol deposit fluid yield is approximately 4～6% of crude drug;
Caulis Fibraureae is soaked for 6～8 times with 0.5% sulphuric acid and extracts, and saltouts, and the fibrauretin yield is about 1.3～1.6% of crude drug weight.
With aforesaid liquid and fibrauretin, Mentholum and with acetic acid Xian must Thailand or ethyl hydroxybenzoate or benzoic acid as antiseptic mix and mix spoon, packing gets final product, its mixed proportion:
Radix Sophorae Flavescentis percolate 40～800g
Fructus Kochiae Fructus Bruceae mixing percolate 60～800g
Fructus Cnidii decocting in water alcohol deposit fluid 0.4～6g
Fibrauretin 2～6g
Mentholum 0.3～1g
Acetic acid Xian must safe 0.5～5g
Enforcement of the present invention:
Take by weighing Radix Sophorae Flavescentis, with 9 times of percolation of 0.5～5% acetic acid, Radix Sophorae Flavescentis percolate yield is about 75% of former acetic acid weight; The Fructus Kochiae, Fructus Bruceae half and half, with 9 times of percolation of 5～20% ethanol, Fructus Kochiae Fructus Bruceae mixing percolate yield is about 75% of former amount of alcohol; It is 1.14 o'clock adding ethanol that Fructus Cnidii, decocting in water, water cooking liquid are concentrated to relative density, makes the ethanol content in the water cooking liquid reach 80%, carries out precipitate with ethanol then and gets its supernatant, and Fructus Cnidii decocting in water alcohol deposit fluid yield is about 5% of crude drug weight; Caulis Fibraureae is soaked for 7 times with 0.5% sulphuric acid and extracts, and saltouts, and the fibrauretin yield is about 1.5% of crude drug weight.With aforesaid liquid and fibrauretin, Mentholum and with acetic acid Xian must Thailand or ethyl hydroxybenzoate or benzoic acid as antiseptic mix and mix thoroughly, packing just obtains product of the present invention, below is the several embodiment that specifically prepare finished medicines:
(1) Radix Sophorae Flavescentis percolate 67.5g, Fructus Kochiae Fructus Bruceae mixing percolate 101g, Fructus Cnidii decocting in water alcohol deposit fluid 0.5g, fibrauretin 3g, Mentholum 0.3g, acetic acid Xian must safe 0.5g.
(2) Radix Sophorae Flavescentis percolate 337.5g, Fructus Kochiae Fructus Bruceae mixing percolate 337.5g, Fructus Cnidii decocting in water alcohol deposit fluid 2.5g, fibrauretin 4.5g, Mentholum 0.6g, ethyl hydroxybenzoate 2.5g.
(3) Radix Sophorae Flavescentis percolate 675g, Fructus Kochiae Fructus Bruceae mixing percolate 675g, Fructus Cnidii decocting in water alcohol deposit fluid 5g, fibrauretin 5g, Mentholum 1g, benzoic acid 5g.
Product of the present invention is done the clinical observation test through The People's Hospital, Guangxi Zhuang Autonomous Region, No.1 Hospital Attached to Guangxi Medical Univ., first Affiliated Hospital of Colleges Of Traditional Chinese Medicine Of Guangxi, pudendal pruritus cure rate due to mycotic, infusorian property, the gonococcal vaginitis is reached more than 85%, and effective percentage reaches more than 95%.
Claims (1)
1. medicine for external use that is used for the treatment of pudendal pruritus is characterized in that Radix Sophorae Flavescentis with 8～10 times of percolation of 0.5～5% acetic acid, and Radix Sophorae Flavescentis percolate yield is approximately 50～80% of former acetic acid amount; The Fructus Kochiae, 8～10 times of percolation of Fructus Bruceae half and half usefulness, 5～20% ethanol, Fructus Kochiae Fructus Bruceae mixing percolate yield is approximately 50～80% of former amount of alcohol; Fructus Cnidii, decocting in water, it is 1.13～1.15 o'clock adding ethanol that water cooking liquid is concentrated to relative density, makes the ethanol content in the water cooking liquid reach 70～90%, carries out precipitate with ethanol and gets its supernatant, Fructus Cnidii decocting in water alcohol deposit fluid yield is approximately 4～6% of crude drug weight; Caulis Fibraureae is soaked for 6～8 times with 0.5% sulphuric acid and extracts, and saltouts, and the fibrauretin yield is approximately 1.3～1.6% of crude drug weight; Merge aforesaid liquid, add fibrauretin, Mentholum and with acetic acid Xian must Thailand or ethyl hydroxybenzoate or benzoic acid as antiseptic mix and mix spoon, packing gets final product, its mixed proportion:
Radix Sophorae Flavescentis percolate 40～800g
Fructus Kochiae Fructus Bruceae mixing percolate 60～800g
Fructus Cnidii decocting in water alcohol deposit fluid 0.4～6g
Fibrauretin 2～6g
Mentholum 0.3～1g
Acetic acid Xian must safe 0.5～5g
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95109270 CN1142368A (en) | 1995-08-05 | 1995-08-05 | External using medicine for pruritus genitalium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95109270 CN1142368A (en) | 1995-08-05 | 1995-08-05 | External using medicine for pruritus genitalium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1142368A true CN1142368A (en) | 1997-02-12 |
Family
ID=5077107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 95109270 Pending CN1142368A (en) | 1995-08-05 | 1995-08-05 | External using medicine for pruritus genitalium |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1142368A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330326C (en) * | 2004-07-21 | 2007-08-08 | 周婕 | Antibicrobial and bacteria inhibiting external use medicine for gynecopathy |
| CN103520593A (en) * | 2013-10-03 | 2014-01-22 | 侯萍 | Chinese herba preparation for treating trichomonas vaginitis and preparation method thereof |
-
1995
- 1995-08-05 CN CN 95109270 patent/CN1142368A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330326C (en) * | 2004-07-21 | 2007-08-08 | 周婕 | Antibicrobial and bacteria inhibiting external use medicine for gynecopathy |
| CN103520593A (en) * | 2013-10-03 | 2014-01-22 | 侯萍 | Chinese herba preparation for treating trichomonas vaginitis and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |