CN102058777A - Traditional Chinese medicine and western medicine-combined formula for radically treating chloasma and preparation process thereof - Google Patents
Traditional Chinese medicine and western medicine-combined formula for radically treating chloasma and preparation process thereof Download PDFInfo
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- CN102058777A CN102058777A CN2009101914875A CN200910191487A CN102058777A CN 102058777 A CN102058777 A CN 102058777A CN 2009101914875 A CN2009101914875 A CN 2009101914875A CN 200910191487 A CN200910191487 A CN 200910191487A CN 102058777 A CN102058777 A CN 102058777A
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Abstract
The invention discloses a traditional Chinese medicine and western medicine-combined formula for removing chloasma at one time and a preparation process thereof. A product prepared according to the formula comprises a liquid medicine A and an ointment B, which are used respectively. The liquid medicine A is prepared from 10 to 50g of white silkworm, 10 to 50g of white poria, 10 to 50g of angelica dahurica, 10 to 50g of thunberg fritillary bulb, 10 to 20ml of bletilla, 10 to 50g of largehead atractylodes rhizome and a proper amount of 75 percent ethanol, and the liquid medicine A is prepared by the following steps of: crushing the white silkworm, the white poria, the angelica dahurica, the thunberg fritillary bulb, the bletilla and the largehead atractylodes rhizome, adding the proper amount of 75 percent ethanol, soaking for 3 to 10 days, removing dregs, and adding the 75 percent ethanol until the total volume is 1,000ml so as to obtain the liquid medicine A; and the ointment B is prepared from 0.03 to 0.1 mg of neomycin, 0.3 to 1 mg of clobetasol propionate, 5 to 15 mg of ketoconazole, a proper amount of glycerol and a proper amount of cream base, and the ointment B is prepared by the following steps of: adding the proper amount of the glycerol into the neomycin, the clobetasol propionate and the ketoconazole and grinding into paste, adding the proper amount of the cream base, and uniformly grinding to prepare the ointment B. The chloasma removing technology is that: the liquid medicine A is applied to an affected part until the chloasma basically disappears, the ointment B is applied to the affected part, and the chloasma can be cured within 20 to 50 days. The invention has a good chloasma removing effect, and ensures no recurrence and no side effect.
Description
Technical field:
The present invention relates to a kind of pharmaceutical formulation and preparation technology and speckle dispelling technology of disposable eliminating chloasma.
Background technology:
The appearance that chloasma influences the people is attractive in appearance, and everybody has a love of beauty, and eliminating chloasma is the pursuit of most of patients.Yet prior art and medicine dispel that the cycle is long, and expense is expensive, and cure rate is low, easily recurrence, and it is not satisfactory to dispel effect, and what have also has side effect, patient's misery.
Summary of the invention:
The technical problem to be solved in the present invention is at the deficiency that prior art exists, to propose a kind of medicine and technology of disposable eliminating chloasma.Effectively eliminating chloasma does not recur.
One of technical scheme of the present invention is: the medicine of described eliminating chloasma is formed and is divided two kinds, medicinal liquid A and ointment B.
(1). the preparation of medicinal liquid A: Bombyx Batryticatus 10-50g Poria 10-50g Radix Angelicae Dahuricae 10-50g Bulbus Fritillariae Thunbergii 10-50g Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20g Rhizoma Atractylodis Macrocephalae 10-50g75% ethanol is an amount of.Get Bombyx Batryticatus, Poria, the Radix Angelicae Dahuricae, Bulbus Fritillariae Thunbergii, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Atractylodis Macrocephalae by above weight portion and pulverize, it is an amount of to add 75% alcohol, soaks 3-10 days, removes medicinal residues, and 75% ethanol gets medicinal liquid A to 1000ml.
(2). the preparation of ointment B: an amount of emulsifiable paste matrix of neomycin 0.03-0.1mg clobetasol propionate 0.3-1mg ketoconazole 5-15mg glycerol is an amount of.Get neomycin, clobetasol propionate, ketoconazole glycerol adding by above weight portion and be ground into pasty state in right amount, add emulsifiable paste matrix grind well in right amount the back ointment B.
(3). the preparation of emulsifiable paste matrix: oil phase: octadecanol 70g stearic acid 130g liquid Paraffin 100g water: glycerol 50g sodium lauryl sulphate 10g methyl p-hydroxybenzoate 0.5g propyl p-hydroxybenzoate 0.5g water is an amount of.Full dose 1000g.Get oil phase and water heats 80 ℃ respectively by above weight portion, when suitable, water adds oil phase to temperature, and the limit edged stirs, and to condensation, promptly gets emulsifiable paste matrix.
Two of technical scheme of the present invention is: the step of described eliminating chloasma is:
(1). use medicinal liquid A earlier: medicinal liquid A is smeared affected part to chloasma disappear substantially.
(2). reuse ointment B: B smears the affected part with ointment.Can cure after 20-50 days.
The medicine for removing speckle of described composition of the present invention can disposable complete eliminating chloasma, leaves no trace.And can keep the microecological balance of skin of face, make it not recur.
As known from the above, the present invention is the medicine and the technology of disposable eliminating chloasma, can effectively dispel the chloasma of human body face.And freckle effect is good, does not recur, and is total effective 97%, do not have any adverse side effect.
The specific embodiment:
Embodiment 1: the medicine of described eliminating chloasma is formed and is divided two kinds, medicinal liquid A and ointment B.
(1). the preparation of medicinal liquid A: Bombyx Batryticatus 10-50g Poria 10-50g Radix Angelicae Dahuricae 10-50g Bulbus Fritillariae Thunbergii 10-50g Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20g Rhizoma Atractylodis Macrocephalae 10-50g75% ethanol is an amount of.Get Bombyx Batryticatus, Poria, the Radix Angelicae Dahuricae, Bulbus Fritillariae Thunbergii, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Atractylodis Macrocephalae by above weight portion and pulverize, it is an amount of to add 75% ethanol, soaks 3-10 days, removes medicinal residues, adds 75% ethanol and gets medicinal liquid A to 1000ml.
(2). the preparation of ointment B: an amount of emulsifiable paste matrix of neomycin 0.03-0.1mg clobetasol propionate 0.3-1mg ketoconazole 5-15mg glycerol is an amount of.Get neomycin, clobetasol propionate, ketoconazole glycerol adding by above weight portion and be ground into pasty state in right amount, add emulsifiable paste matrix grind well in right amount the back ointment B.
(3). the preparation of emulsifiable paste matrix: oil phase: octadecanol 70g stearic acid 130g liquid Paraffin 100g water: glycerol 50g sodium lauryl sulphate 10g methyl p-hydroxybenzoate 0.5g propyl p-hydroxybenzoate 0.5g water is an amount of.Full dose 1000g.Get oil phase and water heats 80 ℃ respectively by above weight portion, when suitable, water adds oil phase to temperature, and the limit edged stirs, and to condensation, promptly gets emulsifiable paste matrix.
Embodiment 2: the step of described eliminating chloasma technology:
(1). use medicinal liquid A earlier: medicinal liquid A is smeared affected part to chloasma disappear substantially.
(2). reuse ointment B: B smears the affected part with ointment.Can cure after 20-50 days.
Claims (2)
1. a Chinese medicine and western medicine is in conjunction with the prescription that effects a radical cure chloasma, and it is characterized in that: it is made up of medicinal liquid A and ointment B.
(1). the preparation of medicinal liquid A: Bombyx Batryticatus 10-50g Poria 10-50g Radix Angelicae Dahuricae 10-50g Bulbus Fritillariae Thunbergii 10-50g Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20ml Rhizoma Atractylodis Macrocephalae 10-50g75% ethanol is an amount of.Get Bombyx Batryticatus, Poria, the Radix Angelicae Dahuricae, Bulbus Fritillariae Thunbergii, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Atractylodis Macrocephalae by above weight portion and pulverize, it is an amount of to add 75% ethanol, soaks 3-10 days, removes medicinal residues, adds 75% ethanol and gets medicinal liquid A to 1000ml.
(2). the preparation of ointment B: an amount of emulsifiable paste matrix of neomycin 0.03-0.1mg clobetasol propionate 0.3-1mg ketoconazole 5-15mg glycerol is an amount of.Get neomycin, clobetasol propionate, ketoconazole glycerol adding by above weight portion and be ground into pasty state in right amount, add emulsifiable paste matrix grind well in right amount the back ointment B.
(3). the preparation of emulsifiable paste matrix: oil phase: octadecanol 70g stearic acid 130g liquid Paraffin 100g water: glycerol 50g sodium lauryl sulphate 10g methyl p-hydroxybenzoate 0.5g propyl p-hydroxybenzoate 0.5g water is an amount of.Full dose 1000g.Get oil phase and water heats 80 ℃ respectively by above weight portion, when suitable, water adds oil phase to temperature, and the limit edged stirs, and to condensation, promptly gets emulsifiable paste matrix.
2. the technology of an eliminating chloasma, it is characterized in that: its step is:
(1). use medicinal liquid A earlier: medicinal liquid A is smeared affected part to chloasma disappear substantially.
(2). reuse ointment B: B smears the affected part with ointment.Can cure after 20-50 days.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101914875A CN102058777A (en) | 2009-11-17 | 2009-11-17 | Traditional Chinese medicine and western medicine-combined formula for radically treating chloasma and preparation process thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101914875A CN102058777A (en) | 2009-11-17 | 2009-11-17 | Traditional Chinese medicine and western medicine-combined formula for radically treating chloasma and preparation process thereof |
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| CN102058777A true CN102058777A (en) | 2011-05-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2009101914875A Pending CN102058777A (en) | 2009-11-17 | 2009-11-17 | Traditional Chinese medicine and western medicine-combined formula for radically treating chloasma and preparation process thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417557A (en) * | 2013-08-14 | 2013-12-04 | 天津药业集团新郑股份有限公司 | Compound ketoconazole cream |
| CN103432148A (en) * | 2013-08-14 | 2013-12-11 | 天津药业集团新郑股份有限公司 | Method for preparing compound ketoconazole cream |
-
2009
- 2009-11-17 CN CN2009101914875A patent/CN102058777A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417557A (en) * | 2013-08-14 | 2013-12-04 | 天津药业集团新郑股份有限公司 | Compound ketoconazole cream |
| CN103432148A (en) * | 2013-08-14 | 2013-12-11 | 天津药业集团新郑股份有限公司 | Method for preparing compound ketoconazole cream |
| CN103432148B (en) * | 2013-08-14 | 2016-03-02 | 遂成药业股份有限公司 | A kind of preparation method of Compound Ketoconazole Cream |
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| PB01 | Publication | ||
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110518 |